Podcasts about Indian Journal

Play Episode Listen Later Mar 17, 2023 61:00

Lecture 2: 'Exploring Nexus' A series of three lectures by Dr. B.S.Chimni, Distinguished Professor of International Law, O.P. Jindal Global University. Previously, he was for over three decades Professor of International Law, School of International Studies, Jawaharlal Nehru University. Between 2004-2006 he was the Vice Chancellor of the W.B. National University of Juridical Sciences, Kolkata. He has been a Visiting Professor at Brown and Tokyo universities, the Graduate Institute, Geneva and the American University of Cairo, and has been visiting fellow at Harvard, Minnesota, and York (Canada) universities and the Institute of Advanced Studies, Nantes. He is an associate member of Institut de Droit International, and Member, Academic Council, Institute for Global Law and Policy (IGLP), Harvard Law School. He is former Vice-President Asian Society of International law and at present Member of its Advisory Council. He is a member of the editorial board of American Journal of International Law and also the former Editor-in-Chief of the Indian Journal of International Law. In 2022 he was honored by the American Society of International Law with its Honorary Membership. The University of London has instituted a scholarship in his name for the MA in Refugee Protection and Forced Migration Studies by distance-learning. He has also received an honorary doctorate from the University of Gothenburg, Sweden. He is the author of International Law and World Order: A Critique of Contemporary Approaches. He is closely associated with the Third World Approaches to International Law (TWAIL) movement.

Hersch Lauterpacht Memorial Lecture 2023: 'Capitalism and the Doctrines of International Law' - Lecture 1: 'Mapping the Terrain' - Dr B S Chimni, Jindal Global University

Play Episode Listen Later Mar 17, 2023 61:00

Lecture 1: 'Mapping the Terrain' A series of three lectures by Dr. B.S.Chimni, Distinguished Professor of International Law, O.P. Jindal Global University. Previously, he was for over three decades Professor of International Law, School of International Studies, Jawaharlal Nehru University. Between 2004-2006 he was the Vice Chancellor of the W.B. National University of Juridical Sciences, Kolkata. He has been a Visiting Professor at Brown and Tokyo universities, the Graduate Institute, Geneva and the American University of Cairo, and has been visiting fellow at Harvard, Minnesota, and York (Canada) universities and the Institute of Advanced Studies, Nantes. He is an associate member of Institut de Droit International, and Member, Academic Council, Institute for Global Law and Policy (IGLP), Harvard Law School. He is former Vice-President Asian Society of International law and at present Member of its Advisory Council. He is a member of the editorial board of American Journal of International Law and also the former Editor-in-Chief of the Indian Journal of International Law. In 2022 he was honored by the American Society of International Law with its Honorary Membership. The University of London has instituted a scholarship in his name for the MA in Refugee Protection and Forced Migration Studies by distance-learning. He has also received an honorary doctorate from the University of Gothenburg, Sweden. He is the author of International Law and World Order: A Critique of Contemporary Approaches. He is closely associated with the Third World Approaches to International Law (TWAIL) movement.

Hersch Lauterpacht Memorial Lecture 2023: 'Capitalism and the Doctrines of International Law' - Lecture 1: 'Mapping the Terrain' - Dr B S Chimni, Jindal Global University

Play Episode Listen Later Mar 17, 2023 61:32

Lecture 1: 'Mapping the Terrain'A series of three lectures by Dr. B.S.Chimni, Distinguished Professor of International Law, O.P. Jindal Global University. Previously, he was for over three decades Professor of International Law, School of International Studies, Jawaharlal Nehru University. Between 2004-2006 he was the Vice Chancellor of the W.B. National University of Juridical Sciences, Kolkata. He has been a Visiting Professor at Brown and Tokyo universities, the Graduate Institute, Geneva and the American University of Cairo, and has been visiting fellow at Harvard, Minnesota, and York (Canada) universities and the Institute of Advanced Studies, Nantes. He is an associate member of Institut de Droit International, and Member, Academic Council, Institute for Global Law and Policy (IGLP), Harvard Law School. He is former Vice-President Asian Society of International law and at present Member of its Advisory Council. He is a member of the editorial board of American Journal of International Law and also the former Editor-in-Chief of the Indian Journal of International Law. In 2022 he was honored by the American Society of International Law with its Honorary Membership. The University of London has instituted a scholarship in his name for the MA in Refugee Protection and Forced Migration Studies by distance-learning. He has also received an honorary doctorate from the University of Gothenburg, Sweden. He is the author of International Law and World Order: A Critique of Contemporary Approaches. He is closely associated with the Third World Approaches to International Law (TWAIL) movement.

Hersch Lauterpacht Memorial Lecture 2023: 'Capitalism and the Doctrines of International Law' - Lecture 2: 'Exploring Nexus' - Dr B S Chimni, Jindal Global University

Play Episode Listen Later Mar 17, 2023 61:48

Lecture 2: 'Exploring Nexus'A series of three lectures by Dr. B.S.Chimni, Distinguished Professor of International Law, O.P. Jindal Global University. Previously, he was for over three decades Professor of International Law, School of International Studies, Jawaharlal Nehru University. Between 2004-2006 he was the Vice Chancellor of the W.B. National University of Juridical Sciences, Kolkata. He has been a Visiting Professor at Brown and Tokyo universities, the Graduate Institute, Geneva and the American University of Cairo, and has been visiting fellow at Harvard, Minnesota, and York (Canada) universities and the Institute of Advanced Studies, Nantes. He is an associate member of Institut de Droit International, and Member, Academic Council, Institute for Global Law and Policy (IGLP), Harvard Law School. He is former Vice-President Asian Society of International law and at present Member of its Advisory Council. He is a member of the editorial board of American Journal of International Law and also the former Editor-in-Chief of the Indian Journal of International Law. In 2022 he was honored by the American Society of International Law with its Honorary Membership. The University of London has instituted a scholarship in his name for the MA in Refugee Protection and Forced Migration Studies by distance-learning. He has also received an honorary doctorate from the University of Gothenburg, Sweden. He is the author of International Law and World Order: A Critique of Contemporary Approaches. He is closely associated with the Third World Approaches to International Law (TWAIL) movement.

Hersch Lauterpacht Memorial Lecture 2023: 'Capitalism and the Doctrines of International Law' - Lecture 3: 'Reframing Doctrines' - Dr B S Chimni, Jindal Global University

Cambridge Law: Public Lectures from the Faculty of Law

Play Episode Listen Later Mar 17, 2023 58:19

Lecture 3: 'Reframing Doctrines'A series of three lectures by Dr. B.S.Chimni, Distinguished Professor of International Law, O.P. Jindal Global University. Previously, he was for over three decades Professor of International Law, School of International Studies, Jawaharlal Nehru University. Between 2004-2006 he was the Vice Chancellor of the W.B. National University of Juridical Sciences, Kolkata. He has been a Visiting Professor at Brown and Tokyo universities, the Graduate Institute, Geneva and the American University of Cairo, and has been visiting fellow at Harvard, Minnesota, and York (Canada) universities and the Institute of Advanced Studies, Nantes. He is an associate member of Institut de Droit International, and Member, Academic Council, Institute for Global Law and Policy (IGLP), Harvard Law School. He is former Vice-President Asian Society of International law and at present Member of its Advisory Council. He is a member of the editorial board of American Journal of International Law and also the former Editor-in-Chief of the Indian Journal of International Law. In 2022 he was honored by the American Society of International Law with its Honorary Membership. The University of London has instituted a scholarship in his name for the MA in Refugee Protection and Forced Migration Studies by distance-learning. He has also received an honorary doctorate from the University of Gothenburg, Sweden. He is the author of International Law and World Order: A Critique of Contemporary Approaches. He is closely associated with the Third World Approaches to International Law (TWAIL) movement.

Hersch Lauterpacht Memorial Lecture 2023: 'Capitalism and the Doctrines of International Law' - Lecture 2: 'Exploring Nexus' - Dr B S Chimni, Jindal Global University

Play Episode Listen Later Mar 17, 2023 61:48

Lecture 2: 'Exploring Nexus'A series of three lectures by Dr. B.S.Chimni, Distinguished Professor of International Law, O.P. Jindal Global University. Previously, he was for over three decades Professor of International Law, School of International Studies, Jawaharlal Nehru University. Between 2004-2006 he was the Vice Chancellor of the W.B. National University of Juridical Sciences, Kolkata. He has been a Visiting Professor at Brown and Tokyo universities, the Graduate Institute, Geneva and the American University of Cairo, and has been visiting fellow at Harvard, Minnesota, and York (Canada) universities and the Institute of Advanced Studies, Nantes. He is an associate member of Institut de Droit International, and Member, Academic Council, Institute for Global Law and Policy (IGLP), Harvard Law School. He is former Vice-President Asian Society of International law and at present Member of its Advisory Council. He is a member of the editorial board of American Journal of International Law and also the former Editor-in-Chief of the Indian Journal of International Law. In 2022 he was honored by the American Society of International Law with its Honorary Membership. The University of London has instituted a scholarship in his name for the MA in Refugee Protection and Forced Migration Studies by distance-learning. He has also received an honorary doctorate from the University of Gothenburg, Sweden. He is the author of International Law and World Order: A Critique of Contemporary Approaches. He is closely associated with the Third World Approaches to International Law (TWAIL) movement.

Hersch Lauterpacht Memorial Lecture 2023: 'Capitalism and the Doctrines of International Law' - Lecture 1: 'Mapping the Terrain' - Dr B S Chimni, Jindal Global University

Cambridge Law: Public Lectures from the Faculty of Law

Play Episode Listen Later Mar 17, 2023 61:32

Lecture 1: 'Mapping the Terrain'A series of three lectures by Dr. B.S.Chimni, Distinguished Professor of International Law, O.P. Jindal Global University. Previously, he was for over three decades Professor of International Law, School of International Studies, Jawaharlal Nehru University. Between 2004-2006 he was the Vice Chancellor of the W.B. National University of Juridical Sciences, Kolkata. He has been a Visiting Professor at Brown and Tokyo universities, the Graduate Institute, Geneva and the American University of Cairo, and has been visiting fellow at Harvard, Minnesota, and York (Canada) universities and the Institute of Advanced Studies, Nantes. He is an associate member of Institut de Droit International, and Member, Academic Council, Institute for Global Law and Policy (IGLP), Harvard Law School. He is former Vice-President Asian Society of International law and at present Member of its Advisory Council. He is a member of the editorial board of American Journal of International Law and also the former Editor-in-Chief of the Indian Journal of International Law. In 2022 he was honored by the American Society of International Law with its Honorary Membership. The University of London has instituted a scholarship in his name for the MA in Refugee Protection and Forced Migration Studies by distance-learning. He has also received an honorary doctorate from the University of Gothenburg, Sweden. He is the author of International Law and World Order: A Critique of Contemporary Approaches. He is closely associated with the Third World Approaches to International Law (TWAIL) movement.

Hersch Lauterpacht Memorial Lecture 2023: 'Capitalism and the Doctrines of International Law' - Lecture 3: 'Reframing Doctrines' - Dr B S Chimni, Jindal Global University

Cambridge Law: Public Lectures from the Faculty of Law

Play Episode Listen Later Mar 17, 2023 58:19

Lecture 3: 'Reframing Doctrines'A series of three lectures by Dr. B.S.Chimni, Distinguished Professor of International Law, O.P. Jindal Global University. Previously, he was for over three decades Professor of International Law, School of International Studies, Jawaharlal Nehru University. Between 2004-2006 he was the Vice Chancellor of the W.B. National University of Juridical Sciences, Kolkata. He has been a Visiting Professor at Brown and Tokyo universities, the Graduate Institute, Geneva and the American University of Cairo, and has been visiting fellow at Harvard, Minnesota, and York (Canada) universities and the Institute of Advanced Studies, Nantes. He is an associate member of Institut de Droit International, and Member, Academic Council, Institute for Global Law and Policy (IGLP), Harvard Law School. He is former Vice-President Asian Society of International law and at present Member of its Advisory Council. He is a member of the editorial board of American Journal of International Law and also the former Editor-in-Chief of the Indian Journal of International Law. In 2022 he was honored by the American Society of International Law with its Honorary Membership. The University of London has instituted a scholarship in his name for the MA in Refugee Protection and Forced Migration Studies by distance-learning. He has also received an honorary doctorate from the University of Gothenburg, Sweden. He is the author of International Law and World Order: A Critique of Contemporary Approaches. He is closely associated with the Third World Approaches to International Law (TWAIL) movement.

Hersch Lauterpacht Memorial Lecture 2023: 'Capitalism and the Doctrines of International Law' - Lecture 1: 'Mapping the Terrain' - Dr B S Chimni, Jindal Global University

Cambridge Law: Public Lectures from the Faculty of Law

Play Episode Listen Later Mar 17, 2023 61:32

Lecture 1: 'Mapping the Terrain'A series of three lectures by Dr. B.S.Chimni, Distinguished Professor of International Law, O.P. Jindal Global University. Previously, he was for over three decades Professor of International Law, School of International Studies, Jawaharlal Nehru University. Between 2004-2006 he was the Vice Chancellor of the W.B. National University of Juridical Sciences, Kolkata. He has been a Visiting Professor at Brown and Tokyo universities, the Graduate Institute, Geneva and the American University of Cairo, and has been visiting fellow at Harvard, Minnesota, and York (Canada) universities and the Institute of Advanced Studies, Nantes. He is an associate member of Institut de Droit International, and Member, Academic Council, Institute for Global Law and Policy (IGLP), Harvard Law School. He is former Vice-President Asian Society of International law and at present Member of its Advisory Council. He is a member of the editorial board of American Journal of International Law and also the former Editor-in-Chief of the Indian Journal of International Law. In 2022 he was honored by the American Society of International Law with its Honorary Membership. The University of London has instituted a scholarship in his name for the MA in Refugee Protection and Forced Migration Studies by distance-learning. He has also received an honorary doctorate from the University of Gothenburg, Sweden. He is the author of International Law and World Order: A Critique of Contemporary Approaches. He is closely associated with the Third World Approaches to International Law (TWAIL) movement.

Hersch Lauterpacht Memorial Lecture 2023: 'Capitalism and the Doctrines of International Law' - Lecture 3: 'Reframing Doctrines' - Dr B S Chimni, Jindal Global University

Cambridge Law: Public Lectures from the Faculty of Law

Play Episode Listen Later Mar 17, 2023 58:19

Lecture 3: 'Reframing Doctrines'A series of three lectures by Dr. B.S.Chimni, Distinguished Professor of International Law, O.P. Jindal Global University. Previously, he was for over three decades Professor of International Law, School of International Studies, Jawaharlal Nehru University. Between 2004-2006 he was the Vice Chancellor of the W.B. National University of Juridical Sciences, Kolkata. He has been a Visiting Professor at Brown and Tokyo universities, the Graduate Institute, Geneva and the American University of Cairo, and has been visiting fellow at Harvard, Minnesota, and York (Canada) universities and the Institute of Advanced Studies, Nantes. He is an associate member of Institut de Droit International, and Member, Academic Council, Institute for Global Law and Policy (IGLP), Harvard Law School. He is former Vice-President Asian Society of International law and at present Member of its Advisory Council. He is a member of the editorial board of American Journal of International Law and also the former Editor-in-Chief of the Indian Journal of International Law. In 2022 he was honored by the American Society of International Law with its Honorary Membership. The University of London has instituted a scholarship in his name for the MA in Refugee Protection and Forced Migration Studies by distance-learning. He has also received an honorary doctorate from the University of Gothenburg, Sweden. He is the author of International Law and World Order: A Critique of Contemporary Approaches. He is closely associated with the Third World Approaches to International Law (TWAIL) movement.

Hersch Lauterpacht Memorial Lecture 2023: 'Capitalism and the Doctrines of International Law' - Lecture 2: 'Exploring Nexus' - Dr B S Chimni, Jindal Global University

Cambridge Law: Public Lectures from the Faculty of Law

Play Episode Listen Later Mar 17, 2023 61:48

Lecture 2: 'Exploring Nexus'A series of three lectures by Dr. B.S.Chimni, Distinguished Professor of International Law, O.P. Jindal Global University. Previously, he was for over three decades Professor of International Law, School of International Studies, Jawaharlal Nehru University. Between 2004-2006 he was the Vice Chancellor of the W.B. National University of Juridical Sciences, Kolkata. He has been a Visiting Professor at Brown and Tokyo universities, the Graduate Institute, Geneva and the American University of Cairo, and has been visiting fellow at Harvard, Minnesota, and York (Canada) universities and the Institute of Advanced Studies, Nantes. He is an associate member of Institut de Droit International, and Member, Academic Council, Institute for Global Law and Policy (IGLP), Harvard Law School. He is former Vice-President Asian Society of International law and at present Member of its Advisory Council. He is a member of the editorial board of American Journal of International Law and also the former Editor-in-Chief of the Indian Journal of International Law. In 2022 he was honored by the American Society of International Law with its Honorary Membership. The University of London has instituted a scholarship in his name for the MA in Refugee Protection and Forced Migration Studies by distance-learning. He has also received an honorary doctorate from the University of Gothenburg, Sweden. He is the author of International Law and World Order: A Critique of Contemporary Approaches. He is closely associated with the Third World Approaches to International Law (TWAIL) movement.

Hersch Lauterpacht Memorial Lecture 2023: 'Capitalism and the Doctrines of International Law' - Lecture 3: 'Reframing Doctrines' - Dr B S Chimni, Jindal Global University

A Tale of Two Hygienists Podcast

Play Episode Listen Later Mar 16, 2023 58:19

Lecture 3: 'Reframing Doctrines' A series of three lectures by Dr. B.S.Chimni, Distinguished Professor of International Law, O.P. Jindal Global University. Previously, he was for over three decades Professor of International Law, School of International Studies, Jawaharlal Nehru University. Between 2004-2006 he was the Vice Chancellor of the W.B. National University of Juridical Sciences, Kolkata. He has been a Visiting Professor at Brown and Tokyo universities, the Graduate Institute, Geneva and the American University of Cairo, and has been visiting fellow at Harvard, Minnesota, and York (Canada) universities and the Institute of Advanced Studies, Nantes. He is an associate member of Institut de Droit International, and Member, Academic Council, Institute for Global Law and Policy (IGLP), Harvard Law School. He is former Vice-President Asian Society of International law and at present Member of its Advisory Council. He is a member of the editorial board of American Journal of International Law and also the former Editor-in-Chief of the Indian Journal of International Law. In 2022 he was honored by the American Society of International Law with its Honorary Membership. The University of London has instituted a scholarship in his name for the MA in Refugee Protection and Forced Migration Studies by distance-learning. He has also received an honorary doctorate from the University of Gothenburg, Sweden. He is the author of International Law and World Order: A Critique of Contemporary Approaches. He is closely associated with the Third World Approaches to International Law (TWAIL) movement.

RRR

Did That Really Happen?

Play Episode Listen Later Jan 23, 2023 70:52

We're back with our first episode of 2023, and we're talking about RRR! Join us as we learn about the Gymkhana Club, riot gear, Lala Lajpat Rai, flogging in the British Raj, and more! Sources: Hansard's Parliamentary Debates, Volume 281 (6 July 1883): https://hansard.parliament.uk/Lords/1883-07-06/debates/53f4430d-fcb5-43e2-b9e1-e478f12fb23d/India-CriminalLaw%E2%80%94PunishmentOfFlogging Sean Lang, "John Nicholson: The Sadistic British Officer Who Was Worshipped As a Living God in India," The Conversation, available at https://theconversation.com/john-nicholson-the-sadistic-british-officer-who-was-worshipped-as-a-living-god-in-india-99889 David Skuy, "Macauley and the Indian Penal Code of 1862: The Myth of the Inherent Superiority and Modernity of the English Legal System Compared to India's Legal System in the 19th Century," Modern Asian Studies 32, 3 (1998) Whipping Act of 1909, Full Text Available at https://www.indiacode.nic.in/repealed-act/repealed_act_documents/A1909-4.pdf Radhika Singha, "The Rare Infliction: The Abolition of Floggin in the Indian Army, circa 1835-1920," Law and History Review 34, 3 (2016) "Discrimination Still Alive and Well in India's Clubs," Irish Times, available at https://www.irishtimes.com/news/discrimination-still-alive-and-well-in-india-s-exclusive-clubs-1.1209302 Amrit Dhillon, "No Dogs or Indians: Colonial Britain Still Rules at India's Private Clubs," Sydney Morning Herald, available at https://www.smh.com.au/world/no-dogs-or-indians-colonial-britain-still-rules-at-indias-private-clubs-20170630-gx1vtk.html "Report of the Committee Appointed in the Government of India to Investigate the Disturbances in the Punjab," 1920, available at https://www.google.com/books/edition/Report_of_the_Committee_Appointed_in_the/u9INAAAAIAAJ?hl=en&gbpv=1&dq=delhi+gymkhana+club&pg=PA2&printsec=frontcover Vinay Lal, "Hinduism," in The Oxford Encyclopedia of the Modern World edited by Peter N. Stearns (Oxford University Press, 2008). C.V. Mathew, "Arya Samaj," in The Oxford Encyclopaedia of South Asian Christianity edited by Roger E. Hedlund, Jesudas M. Athyal, Joshua Kalapati, and Jessica Richard (Oxford University Press, 2011). "Hindu Nationalism," in The Oxford International Encyclopedia of Legal History edited by Stanley N. Katz (Oxford University Press, 2009). "Hindu nationalism," in A Concise Oxford Dictionary of Politics and International Relations edited by Garrett W. Brown, Iain McLean, and Alistair McMillan (Oxford University Press, 2018). Christophe Jaffrelot, "Madan Mohan Malaviya and Lala Lajpat Rai," in Hindu Nationalism: A Reader (Princeton University Press, 2007). https://www.jstor.org/stable/j.ctt7s415.9 D.P. Singh, "Lala Lajpat Rai: His Life, Times and Contributions to Indian Polity," The Indian Journal of Political Science 52, no.1 (1991): 125-36. https://www.jstor.org/stable/41855539 Vanya Bhargav, "Lala Lajpat Rai's Ideas on Caste: Conservative or Radical?" Studies in Indian Politics 6, no.1 (2018): 15-26. J.S. Bains, "Lala Lajpat Rai's Idealism and Indian National Movement," The Indian Journal of Political Science 46, no. 4 (1985): 401-20. S.R. Bhakshi and S.R. Bhakshl, "Simon Commission and Lajpat Rai: An Assessment," Porceedings of the Indian History Congress 50 (1989): 507-18. Saṅgīt Mahābhāratī, "Vandé Mātaram," in The Oxford Encyclopedia of the Music of India (Oxford University Press, 2011). Martin Thomas, "'Poying the Butcher's Bill': Policing British Colonial Protest after 1918," Crime, History & Societies 15, no.2 (2011): 55-76. https://www.jstor.org/stable/42708833 Aftab Nabi, "Consolidating the British Empire: The Structure, Orientation, and Role of Policing in Colonial Africa and Asia," Pakistan Horizon 69, no.2 (2016): 47-77. https://www.jstor.org/stable/44988203 David Arnold, "The Police and Colonial Control in South India," Social Scientist, 4, no. 12 (1976): 3-16. https://www.jstor.org/stable/3516332 Simeon Shoul, "Soldiers, Riot Control and Aid to the Civil Power in India, Egypt and Palestine, 1919-39," Journal of the Society for Army Historical Research 86, no. 346 (2008): 120-39. https://www.jstor.org/stable/44231576 Prashant Kidambi, "'The ultimate masters of the city': police, public order and the poor in colonial Bombay, c. 1893-1914," Crime, History & Societies 8, no.1 (2004): 27-47. https://www.jstor.org/stable/42708561 John Powers, "If you haven't been back to the movies yet, Indian epic 'RRR' is the reason to go," NPR (11 October 2022). https://www.npr.org/2022/10/11/1127995338/rrr-review--rajamouli-indian-epic-cult-following Steve Rose, "Best movies of 2022 in the US: No 5 - RRR" The Guardian (19 December 2022). https://www.theguardian.com/film/2022/dec/19/best-movies-of-2022-in-the-us-no-5-rrr Glen Weldon et al, "'RRR' is an inteRRRnational phenomenon," Pop Culture Happy Hour, NPR (11 July 2022). https://www.npr.org/2022/06/24/1107301440/rrr-is-an-interrrnational-phenomenon Nitish Pahwa, "A Wild Indian Blockbuster is Ravishing Movie Fans, but They're Missing Its Troubling Subtext," Slate (8 June 2022). https://slate.com/culture/2022/06/rrr-review-indian-blockbuster-netflix-hindu-nationalism.html Rotten Tomatoes, https://www.rottentomatoes.com/m/rrr

music conversations politics law society government ideas police crime indian journal myth npr studies soldiers radical palestine lords political science clubs slate singh butcher hindu policing international relations rotten tomatoes living god investigate modern world aid hinduism orientation contributions bombay modernity punjab disturbances sydney morning herald rrr legal system irish times mah bains idealism south india consolidating indian army david arnold social scientists us no legal history macauley pop culture happy hour british raj indian politics hindu nationalism john powers martin thomas indian journal glen weldon indian penal code colonial africa oxford encyclopedia christophe jaffrelot history review steve rose riot control nitish pahwa iain mclean

Pumpkin, Patients, and Periodontitis! OH MY! "Fast Facts: Perio Edition"

Play Episode Listen Later Nov 14, 2022 4:37

This week we are loving up on Thanksgiving once again, this time talking about a favorite dessert, and that is of course pumpkin pie. Who doesn't love it when your waistband is so stretched out from that fabulous Thanksgiving dinner and yet you still find a little bit more room for a tiny little slice of pumpkin pie? Today we discuss pumpkin, and the effects of pumpkin on the periodontium. Quotes: “In fact, pumpkin is extremely dense in vitamin A. We know that vitamin A plays a critical role in being able to create sustainability in health in the oral cavity. In fact, vitamin A plays a key role in the maintenance of our oral epithelium.” “We actually found conclusively in this study that pumpkin seed oil is a potent anti-inflammatory agent that can be used topically for the treatment of gingivitis without any subsequent side effects.” Resources: DentistRX: https://www.dentistrx.com More Fast Facts: https://www.ataleoftwohygienists.com/fast-facts/ Katrina Sanders Website: https://www.katrinasanders.com Katrina Sanders Instagram: https://www.instagram.com/thedentalwinegenist/ Moynihan, P., & RPHNutr, S. R. D. (2008). Update on nutrition and periodontal disease. inflammation, 6,7.Othman, A. A., Saleh, M. F., & Saleh, T. M. (2019). The Anti Inflammatory Effect of Pumpkin Seeds Oil in Treatment of Gingivitis; Clinical Study. Indian Journal of Public Health Research & Development,10(10).

thanksgiving patients treatments pumpkin saleh moynihan othman fast facts gingivitis indian journal periodontitis

Pumpkin, Patients, and Periodontitis! OH MY! "Fast Facts: Perio Edition"

A Tale of Two Hygienists Podcast

Play Episode Listen Later Nov 14, 2022 4:37

This week we are loving up on Thanksgiving once again, this time talking about a favorite dessert, and that is of course pumpkin pie. Who doesn't love it when your waistband is so stretched out from that fabulous Thanksgiving dinner and yet you still find a little bit more room for a tiny little slice of pumpkin pie? Today we discuss pumpkin, and the effects of pumpkin on the periodontium. Quotes: “In fact, pumpkin is extremely dense in vitamin A. We know that vitamin A plays a critical role in being able to create sustainability in health in the oral cavity. In fact, vitamin A plays a key role in the maintenance of our oral epithelium.” “We actually found conclusively in this study that pumpkin seed oil is a potent anti-inflammatory agent that can be used topically for the treatment of gingivitis without any subsequent side effects.” Resources: DentistRX: https://www.dentistrx.com More Fast Facts: https://www.ataleoftwohygienists.com/fast-facts/ Katrina Sanders Website: https://www.katrinasanders.com Katrina Sanders Instagram: https://www.instagram.com/thedentalwinegenist/ Moynihan, P., & RPHNutr, S. R. D. (2008). Update on nutrition and periodontal disease. inflammation, 6,7.Othman, A. A., Saleh, M. F., & Saleh, T. M. (2019). The Anti Inflammatory Effect of Pumpkin Seeds Oil in Treatment of Gingivitis; Clinical Study. Indian Journal of Public Health Research & Development,10(10).

thanksgiving patients treatments pumpkin saleh moynihan othman fast facts gingivitis indian journal periodontitis

162 Cellulite

The Body Nerd Show

Play Episode Listen Later May 5, 2022 23:40

I don't know about you, but I'm very familiar with how media, fashion, advertising, and the fitness industry makes us feel crappy about our capable, amazing bodies. Enter cellulite. And you'd think that for as much money is spent on the treatment of cellulite, there would be more research on it. Yet the literature, including peer-reviewed research, is a little wild to wade through - and there is more information on treatment than there is on the cause. Cellulite isn't an issue to be solved - it's a totally normal tissue layer in your body. And understanding how fascial health is related to its appearance may help you better understand what's going on and how to take excellent care of it. So if you're concerned about cellulite, today's episode is for you! You'll learn: The science of cellulite and what it is Latest cellulite research And what your fascial health has to do with the appearance of cellulite All the links: Cybil's Website - csolyn.com Cybil is @skinfitnessexpert on IG Circadia Professional Firming and Shaping Gel The Body Nerd Show Episode 17: What's Fascia Got to Do With It? The Anatomical Basis of Cellulite Dimple Formation: An Ultrasound-Based Examination Anatomical study of superficial fascia and localized fat deposits of abdomen (Indian Journal of Plastic Surgery) Cellulite isn't Real. This is How it was Invented. (Refinery 29) Scientific American - Is Cellulite Forever? **** Treatment for Cellulite (International Journal of Women's Dermatology) 30 days to more strength + flexibility with the Mobility Mastery Toolkit Movement Mavens has the tools and strategy to support you on your path to enjoying life without pain - www.aewellness.com/mavens www.aewellness.com/podcast - Show notes, links and more. Join the free Body Nerds FB community: https://www.facebook.com/groups/aewbodynerds/ Come hang out with me on Instagram @hollaformala : https://instagram.com/hollaformala/ TikTok @ aewellness Bodywork Starter Guide - learn the 6 places you need to roll right now for quick relief, plus the reason why what you've tried so far has only given you a temporary fix. Download the guide for free now at www.aewellness.com/bodywork 818-396-6501 is the Body Nerd Hotline - how do you build consistency and/or where are you getting stuck? Drop me a line and let me know your body nerd hacks - you might just hear your voice on a future episode! Today's episode is brought to you by AE Wellness Mobility Assessments. Not sure what you should be doing for mobility? Instead of trying a bazillion things and spending hours a day, get strategic coaching with a Mobility Assessment... with me! You'll get your personalized mobility workout plan with the best mobilizations and activations for you, plus all the videos organized in custom playlists to keep things simple. Save $50 off your Mobility Assessment when you use code BODYNERD at www.aewellness.com/mobility/

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Law Schools, Writing and More with Mr. Aradhya Sethia | Cambridge International Scholar

THE ONE TAKE SHOW: Law, Logic and Life with Kaustubh

Play Episode Listen Later Apr 20, 2022 50:19

The One Take Show is honoured to host Mr Aradhya Sethia. Aradhya Sethia is a PhD Candidate and Cambridge International Scholar at the University of Cambridge, where he is studying the role and regulation of political parties and party systems in modern constitutional states. Aradhya is a supervisor in constitutional law and Human Rights Law at Cambridge and an Executive Director of the Cambridge Pro Bono Project. He has previously taught at the National Law School of India University, Bangalore. Before joining Cambridge, Aradhya was a Bonavero Institute Summer Fellow at the British Institute of International and Comparative Law and read for MPhil at the University of Oxford. In 2018, Aradhya completed LL.M. at Yale Law School as an Inlaks Scholar served as a resident fellow at Yale Information Society Project, an articles editor of the Yale Journal of International Law, and a member of the Lowenstein International Human Rights Project. Subsequently, he was a visiting scholar and Yale Fox International Fellow at the Centre for Comparative Constitutional Studies, Melbourne Law School. He received the 2019 Indian Law Review Best Article Prize for his article 'Where's the Party?: Towards a Constitutional Biography of Political Parties'. He has previously assisted Justice D.Y. Chandrachud (the Supreme Court of India), Justice S. Ravindra Bhat (High Court of Delhi), and the Attorney General for India. He has also assisted with the drafting of the Law Commission of India reports on electoral reforms. He received his BA LLB from the National Law School of India University, India (NLSIU) as the Best Outgoing Student (2017), and won three gold medals including H.M. Seervai Medal in Constitutional Law. At NLSIU, Aradhya served as the Joint Convener of the Legal Services Clinic, editor-in-chief of the Indian Journal of Law and Technology, and editor of the National Law School of India Review. Aradhya has authored columns for Dainik Bhaskar, Dainik Jagaran, Indian Express, and The Hindu, and has appeared on various public forums to discuss his research and insights on political and constitutional developments in India. The One Take Show Podcast, Law, Logic and life, where we discuss the various developments in the field of Law and Policy, discuss the success stories and mentorship, take career advice, talk logic and ethics, discuss cinema and art, and have a lot of fun!

The invisible influence of sexism on science

The Sleep Whisperer Podcast

Play Episode Listen Later Mar 31, 2022 29:20

March 8 is International Women’s day. We have two episodes this month on how gendered understanding of science affects the way research is conducted. The first episode describes the protests led by feminist organisations on the unethical trials on contraceptive injections starting from the 80s till more recently. Conversely, we also discuss how there are very few women and almost no transgender persons enrolled in clinical trials which gives a very limited understanding of the impact of new drugs. In this episode, Suno India’s Menaka Rao speaks to Dr Vineeta Bal, Dr Sunita Bandewar and Sayantan Datta. Dr Bal is an immunologist who worked at the National Institute of Immunology and is now a visiting faculty at Indian Institute of Science, Education and Research, Pune. Dr Bandewar is one of the working editors of Indian Journal of Medical Ethics and independent researcher in the area of bioethics and global health. Sayantan Datta, a queer-trans science journalist and communicator who writes for feminist multimedia science collective, Life of Science. They also teach writing and communication at Krea University, in Andhra Pradesh. The show is hosted by Menaka Rao and Padmapriya DVL. See sunoindia.in/privacy-policy for privacy information.

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110 - Sleep & Endocrine Health With Dr Anurag Bajpai, MD

Play Episode Listen Later Feb 22, 2022 50:13

Dr. Anurag Bajpai underwent postgraduate training from All India Institute of Medical Sciences, New Delhi. He was awarded Fellowship in endocrinology by the Royal College of Physicians (FRACP). He has authored over fifty indexed papers, thirty text-book chapters and two books related to paediatric endocrinology. Dr. Anurag Bajpai is the section editor for endocrinology in Indian Journal of Pediatrics, reviewer for Pediatrics, Indian Pediatrics, Journal of Pediatrics and Journal of Paediatric Endocrinology and Metabolism. His area of research includes the role of estrogen in peripubertal males, neuroprotective effects of insulin like growth factor I, growth hormone deficiency, pubertal disorders, obesity, rickets, congenital adrenal hyperplasia and type 1 diabetes mellitus. He has authored Practical Paediatric Endocrinology and Children with Diabetes. Dr. Anurag Bajpai has taken active interest in spreading awareness about paediatric endocrinology and has set up Grow India, a non governmental initiative to improve care of children with growth disorders. Why is sleep important for the endocrine system? What happens to the hormones when we sleep? What are the effects of lack of sleep on hormones? What are the effects of sleep disorders on growth, metabolism, obesity, reproduction and glucose metabolism? How do different circadian rhythms affect the endocrine system? What is the connection between medication effect and circadian rhythm in hypothyroidism? What would be the ideal sleep regimen for optimal endocrine function? For more on Dr Anurag Bajpai you can follow him: Website: http://dranuragbajpai.com Paediatric Endocrine Learning: https://learning.growsociety.in Youtube: https://www.youtube.com/channel/UCRM4NL33J33YErh3939cJLA Facebook: https://www.facebook.com/growindia.org/ Online appointment: https://www.practo.com/kanpur/doctor/anurag-bajpai-pediatrician Related Episodes: 103 - Detoxification, Women's Hormones & Sleep With Dr Wendie Trubow 100 - Women's Health, Hormones & Essential Oils For Sleep With Mama Z 097 - Living A Circadian Life With Bastion Groiss 075 - Light & Circadian Rhythm Masterclass With Roudy Nassif 027 - Insulin Resistance & Sleep with Dr Benjamin Bikman -For more on Deepa: Deepa is an Allied Functional Medicine Practitioner, Author and a Yogini at Phytothrive. Having a son with a rare adrenal disorder gave her insight into the working of the adrenals. Her articles have been shared by Dr Mark Hyman, MD, a 14 times NY Times Bestselling Author. She also gave the opening speech on Health Hacks at Amazon Web Services & YourStory HeathTech 2019 to heads of healthcare start-ups in India. She is in the YourStory100 Digital Influencers Of 2020. Her book on sleep with HarperCollins releases in 2022. She has been featured on the award winning podcast 15-Minute Matrix discussing sleep. Weekly Newsletter:

The Gary Null Show - 02.18.22

The Gary Null Show

Play Episode Listen Later Feb 18, 2022 61:06

Mortality lower during five-year period among adults who supplemented with calcium plus vitamin D Thirumalai Mission Hospital (India), February 16 2022. A study published in the Indian Journal of Endocrinology and Metabolism found a decrease in fractures and mortality during a 5-year average follow-up period among individuals who regularly supplemented with calcium and vitamin D. The study involved participants in a community-based osteoporosis detection program that included women aged 50 and older who had been postmenopausal for five years and men over the age of 55. Osteoporosis and osteopenia were detected among 2,882 participants, who were subsequently advised to consume 500 mg calcium and 250 IU of vitamin D3 per day. These participants were additionally offered annual injections of 600,000 IU vitamin D3. The current analysis was limited to 2,113 participants among this group who were not treated with prescription drug therapy for severe osteoporosis and who were followed for at least two years. Among those who supplemented regularly, the risks of experiencing a fracture or death were respectively 73% and 47% lower during the 5-year average follow-up compared to those who failed to adhere to the regimen. (NEXT) Black walnuts found to suppress appetite and oxidative degradation of lipids University of Georgia, February 3, 2022 Researchers have found that adding black walnuts (Juglans nigra) to your breakfast not only helps you feel fuller, but also protects your cells from oxidative damage. In their report, which was published in the journal Nutrition Research, the team explored the benefits of using black walnuts as a butter substitute. In their report, the team noted that most studies on the health benefits of walnuts use English walnuts, which have a different nutritional profile than black walnuts. While walnuts are nutrient-dense, they argued that black walnuts have more protein than the more popular English walnuts. Black walnuts, they proposed, can improve satiety and even regulate postprandial increases in lipid peroxidation better than English walnuts. A total of 30 healthy adults participated in the randomized, double-blind control crossover study. At each testing visit, the participants were asked to eat a breakfast meal that had either butter (which served as the control) or a butter substitute (black walnut or English walnut). After three testing visits, the team noted that participants who ate black walnuts reported feeling fuller than those who had English walnut and butter. In addition, they had greater suppression of lipid peroxidation after eating. “Substituting butter in a breakfast meal with [black walnuts] or [English walnuts] increased fullness; however, the [black walnut] meal was superior for suppressing overall appetite while also lowering postprandial lipid peroxidation,” the team wrote in their report. (NEXT) Human brain doesn't slow down until after 60 Heidelberg University's Institute of Psychology, February 17, 2022 You used to be able to make snap judgments in your 20s, but now it feels like you take a lot longer to react to questions, decisions and challenges put before you. Don't fret, it's not that you're losing brain power. Your response time does tend to slow down as you age, but a new study argues that's not because your brain's processing speed is deteriorating. Your brain remains as nimble as ever until you hit your 60s, according to a report published Feb. 17 in the journal Nature Human Behaviour. "Our research now shows that this slowing is not due to a reduction in cognitive processing speed," von Krause said. "Until older adulthood, the speed of information processing in the task we studied barely changes." (NEXT) Study shows exercise can help older adults retain their memories We all know exercise is good for us, but that still leaves plenty of questions. How much exercise? Who benefits the most? And when in our lives? New research led by University of Pittsburgh psychologists found that it seems like exercising about three times a week for at least four months is how much you need to reap the benefits in episodic memory." Episodic memory is the kind that deals with events that happened to you in the past. It's also one of the first to decline with age. "I usually like to talk about the first time you got behind the wheel of a car," said Aghjayan. "So you might remember where you were, how old you were, who was in the passenger seat explaining things to you, that feeling of excitement." Seeking clarity in the muddy waters of the scientific literature, the team pored over 1,279 studies, eventually narrowing them down to just 36 that met specific criteria. The researchers found that pooling together those 36 studies was enough to show that for older adults, exercise can indeed benefit their memory. (NEXT) Prevention Against Gallstones - Eat More Foods With Vitamin E University of Kiel (Germany), February 16, 2022 More than 90 percent of the population does not meet their recommended daily allowance of vitamin E. Researchers in Germany led by the University of Kiel found that subjects with gallstone disease had lower blood levels of vitamin E than those who did not have gallstones. Vitamin E does everything from ease exercise soreness, treating menstrual pain, preventing cancer and playing a central role in neurological and cardiovascular function. Adequate levels of vitamin E, an essential micronutrient, are especially critical for the very young. The scientists also found that those with gallstone disease also had a lower alpha-tocopherol/cholesterol ratio than healthy individuals. A similar association was found with gamma-tocopherol levels. However, with the gamma form, the results were not statistically significant. (OTHER NEWS) How Medicare is quietly being privatized By Abdul El-Sayed, M.D. Detroit Metro Times, February 9, 2022 Healthcare is big business — literally one of the most lucrative corporate endeavors in the country, accounting for one-fifth of our total economy. And the way that the business of healthcare interferes with actually providing Americans with appropriate, accessible, and affordable healthcare has been a frequent subject of my writing in these pages. From hospital consolidation to drug pricing, rising premiums to healthcare inequities, the fact that our healthcare system is designed to maximize profit for a few large corporations is the root, if not all, of the problem. The fattest slice of that very, very large pie is healthcare for seniors — the Americans who most often need care. American seniors are insured through Medicare, a government health insurance program that's supposed to offer them affordable, comprehensive healthcare. But as this is the American healthcare system we're talking about, the knives are constantly out for Medicare — looking for just another bite. Late last year, I wrote about the Medicare (dis)Advantage program, a frontal assault on Medicare, which cajoles beneficiaries into selecting privately managed Medicare plans. The private health insurance corporations that administer these plans get to keep the money they don't spend on healthcare as profit, putting $27 billion of taxpayer moneyinto the pockets of health insurance corporations in 2018 alone. As bad as Medicare Advantage is, a new plan hatched under the Trump administration — and being allowed to proceed under the Biden administration — is even worse. But unlike Medicare Advantage, most seniors haven't even heard about it. It's called Direct Contracting. Designed by the Trump administration, it's a sop to the health insurance corporations and private equity firms that have been such a persistent force in Republican healthcare circles. They agree on a simple goal: privatize everything. Instead of cajoling seniors to hand over their Medicare dollars, large corporations, called Direct Contracting Entities, target doctors. When a doctor signs up, all of the Medicare beneficiaries they see are signed up too — without their knowledge or consent. The Direct Contracting Entity acts as a middleman between the physician and Medicare — and like Medicare Advantage, they profit off of the Medicare dollars that aren't spent on beneficiaries. In exchange for signing up, the doctors earn a kickback from the Direct Contracting Entity. But Direct Contracting isn't a matter of law; Congress never voted on this. It's just a pilot program designed by the Trump administration … that the Biden administration is now carrying forward. They could kill Direct Contracting in its tracks if they wanted to! The fact that it's not should be extremely worrying to seniors, consumer rights advocates, and anyone who pays taxes to the U.S. government. The irony here is that President Biden ran on a public option — which doesn't look to be coming anytime soon. Instead of that promise, his administration is allowing a backdoor private buyout of Medicare.

Why forcing people to take vaccines doesn't work

Microsoft Research India Podcast

Play Episode Listen Later Jan 24, 2022 18:30

Only about 65% of the eligible Indian population above the age of 18 has completed both doses of the COVID-19 vaccination. With the third wave setting in, many governments announced different kinds of punitive measures for not having completed vaccines. In Kerala, the state will not provide free treatment for those not vaccinated fully. Some states such as Delhi and Maharashtra have made it compulsory for government employees to be vaccinated. In Haryana entry into banks, malls, and other public places is not allowed if you are not fully vaccinated. In the past, we have had local governments announce stopping of ration, or other social security measures. Do such measures work? The question becomes even more important as the government announced vaccination for teenagers between the age of 15-18 and an additional protective dose for health workers and senior citizens. Suno India's Menaka Rao spoke to Dr Sunita Sheel Bandewar and Dr Prabir Chatterjee. Sunita is one of the working editors of the Indian Journal of Medical Ethics and an independent researcher in the area of bioethics and global health. Dr Chatterjee is a senior public health professional and was director of State Health Resource Centre, a technical support institute for the state's health ministry. Show notes Press briefing on the actions taken, preparedness and updates on COVID-19, Dated: 05.01.2022 No free Covid treatment to unvaccinated, says Kerala CM Pinarayi Vijayan | Thiruvananthapuram News – Times of India Data | India falls short of December 31 vaccination target – The Hindu AEFI Reports | Ministry of Health and Family Welfare | GOI See sunoindia.in/privacy-policy for privacy information.

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Collaborating to Develop a Low-cost Keratoconus Diagnostic Solution. With Dr. Kaushik Murali and Dr. Mohit Jain

Play Episode Listen Later Jan 17, 2022 27:44

Episode 011 | January 18, 2022Keratoconus is a severe eye disease that affects the cornea, causing it to become weak and develop a conical bulge. Keratoconus, if undiagnosed and entreated, can lead to partial or complete blindness in people affected by it. However, the equipment needed to diagnose keratoconus is expensive and non-portable, which makes early detection of keratoconus inaccessible to large populations in low and middle income countries. This makes it a leading cause for partial or complete blindness amongst such populations. Doctors from Sankara Eye Hospital, Bengaluru and researchers from Microsoft Research India have been working together to develop SmartKC, a low-cost and portable diagnostic system that can enable early detection and mitigation of keratoconus. Join us as we speak to Dr. Kaushik Murali from Sankara Eye Hospital and Dr. Mohit Jain from Microsoft Research India.Dr. Kaushik Murali, President Medical Administration, Quality & Education, Sankara Eye Foundation India (Sri Kanchi Kamakoti Medical Trust) which is among the largest structured community eye hospital network in India, (www.sankaraeye.com) with an objective of providing world class eye care with a social impact. A paediatric ophthalmologist, Dr. Kaushik has completed a General Management Programme and is an alumnus of Insead. He has done a course on Strategic Management of Non Profits at the Harvard Business School. He has been certified in infection control, risk management for health care and digital disruption. He is a member of Scalabl, a global community promoting entrepreneurship. Dr. Kaushik is a member of the Scientific Committee of Vision 2020, the Right to Sight India. He is currently involved in collaborative research projects among others with the University of Bonn & Microsoft.Dr. Kaushik has received many recognitions, key among them being the Bernadotte Foundation for Children's Eyecare Travel Grant, Mother Teresa Social Leadership Scholarship ,International Eye Health Hero, All India Ophthalmological Society best research, International Association for Prevention of Blindness (IAPB) Eye Health Hero, Indian Journal of Ophthalmology Certificate of Merit. Beyond the medical world, he is part of the National Management Team of Young Indians – Confederation of Indian Industry (CII). He represented India at G20 Young Entrepreneur Alliance 2018 at Argentina and led the Indian delegation for the Inaugural India- Israel Young Leaders Forum in 2019. More recently, he led the first citizen's cohort for a workshop on Strategic Leadership at LBSNAA (Lal Bahadur Shastri National Academy of Administration). Mohit Jain is a Senior Researcher in the Technology and Empowerment (TEM) group at Microsoft Research India. His research interests lie at the intersection of Human Computer Interaction and Artificial Intelligence. Currently, he focuses on developing end-to-end systems providing low-cost smartphone-based patient diagnostic solutions for critical diseases. Over the past decade, he has worked on technological solutions for the developing regions focusing on health, accessibility, education, sustainability, and agriculture.He received his Ph.D. in Computer Science & Engineering from the University of Washington, focusing on extending interactivity, accessibility and security of conversational systems. While pursuing his Ph.D., he also worked as a Senior Research Engineer in the Cognitive IoT team at IBM Research India. Prior to that, he graduated with a Masters in Computer Science from the University of Toronto, and a Bachelors in Information and Communication Technology from DA-IICT.For more information about the SmartKC project, and for project related code, click here.For more information about the Microsoft Research India click here.RelatedMicrosoft Research India Podcast: More podcasts from MSR IndiaiTunes: Subscribe and listen to new podcasts on iTunesAndroidRSS FeedSpotifyGoogle PodcastsEmailTranscript Dr. Murali Kaushik: Sitting in an eye hospital, often we have ideas, but we have no clue whom to ask. But honestly, now we know that there is a team at MSR that we can reach out to saying that hey, here is a problem, we think this warrants attention. Do you think you guys can solve it? And we found that works really well. So, this kind of a collaboration is, I think, a phenomenal impact that this project has brought together, and we hope that together we will be able to come up with few more solutions that can align with our founders' dream of eliminating needless blindness from India. [Music]Sridhar Vedantham: Welcome to the Microsoft Research India podcast, where we explore cutting-edge research that's impacting technology and society. I'm your host, Sridhar Vedantham.[Music]Sridhar Vedantham: Keratoconus is a severe eye disease that affects the cornea, causing it to become weak and develop a conical bulge. Keratoconus, if undiagnosed and entreated, can lead to partial or complete blindness in people affected by it. However, the equipment needed to diagnose keratoconus is expensive and non-portable, which makes early detection of keratoconus inaccessible to large populations in low and middle income countries. This makes it a leading cause for partial or complete blindness amongst such populations. Doctors from Sankara Eye Hospital, Bengaluru and researchers from Microsoft Research India have been working together to develop SmartKC, a low-cost and portable diagnostic system that can enable early detection and mitigation of keratoconus. Join us as we speak to Dr. Kaushik Murali from Sankara Eye Hospital and Dr. Mohit Jain from Microsoft Research India. [Music] Sridhar Vedantham: So, Dr. Kaushik and Mohit, welcome to the podcast. Mohit Jain: Hi, Sridhar. Dr. Kaushik Murali: Hi Sridhar, pleasure to be here. Sridhar Vedantham: It's our pleasure to host you, Doctor Kaushik, and for me this is going to be a really interesting podcast for a couple of reasons. One is that the topic itself is kind of so far afield from what I normally here at Microsoft Research and the second is I think you're the first guest we are having on the podcast who's actually not part of MSR, so basically a collaborator. So, this is really exciting for me. So let me jump right into this. We're going to be talking about something called keratoconus, so could you educate us a little bit as to what keratoconus actually is and what its impact is? Dr. Kaushik Murali: So, imagine that you were a 14-year-old who was essentially near sighted. You wore glasses and you were able to see. But with passing time, your vision became more distorted rather than being blurred, which is what you would have expected if just your minus power kept increasing, especially for distance. And to add to your misery, you started seeing more glare and more halos at nighttime. Words that you started to read had shadows around them or even started to look doubled. This essentially is the world of a person with Keratoconus. Literally it means cone shaped. Keratoconus is a condition of the cornea, which is the transparent front part of the eye, similar to your watch glass, where instead of it normally retaining its dome shape, it is characterized by progressive thinning and weakening of the central part, what we call as a stroma, and this makes the cornea take on a conical shape. In a few, this can actually even progress beyond what I describe, where the central cornea overtime becomes scarred and the person could no longer be corrected, with just optical devices like a glass or a contact lens but may actually end up requiring a corneal transplant. Sridhar Vedantham: I see, and what are the causes for this? Dr. Kaushik Murali: So there have been very many causes that have been attributed, so it's thought to be multifactorial. So, this again makes it a little tricky in terms of us not being able to prevent the condition, so to speak. But multiple risk factors are known. Ultraviolet exposure, chronic allergies; habitual eye rubber is thought to be more prone for this. Essentially, you end up seeing it more during the pubertal age group, and more in men. Sridhar Vedantham: I see. And how widespread is this problem, really? Because frankly, I'm of course as lay a person as you can get, and I hadn't really heard of eye disease called keratoconus until I spoke to Mohit at some point and then of course after reading papers and so on. But what is the extent of the issue and is it really that widespread a problem? Dr. Kaushik Murali: So, unlike most other conditions, there is no real population-based survey where we have screened every household to arrive at numbers. But largely, we base our estimation on small surveys that have been done across different parts of the world. Based on this, we estimate that it is approximately affecting about one in 2000 individuals. So, in the US, for example, it is thought to affect almost about 55 people in about 100,000, who had been diagnosed with keratoconus. But in countries like India, it is thought to be more widespread. So there was actually a survey in central India where they found almost 2300 people out of 100,000 people being affected with keratoconus. So, the numbers are quite large. And again, all of this could be underestimated simply because we don't have enough ability to screen. And what makes this number even scarier is this is a disease that typically affects people between the age group of 10 and 25. So, once they're affected and they're progressively going to have their vision come down, they're going to spend most of their protective years not being able to see clearly. Sridhar Vedantham: OK, that is kind of scary. Mohit Jain: I would just like to add to that is that there is actually a combination of demographics, genetic and weather condition which makes India a really good host for this disease. So, apparently Indian population tend to have a thinner and steeper cornea to begin with and moreover the hot and humid climate of India actually contribute towards keratoconus because it causes irritation which leads to frequent rubbing of the eye and that can actually start the process of distortion of the cornea. Sridhar Vedantham: OK, so that just made the problem sound a little scarier because there are these conditions that cannot be altered, right? I mean climate and stuff like that we can't really change. Uh, OK, doctor, so, this is basically a well-established and recognized disease, right? So, what are the barriers and hurdles actually to effective diagnosis and treatment of this disease? Dr. Kaushik Murali: So, in any health intervention the barriers typically are availability, accessibility and affordability. And when you look at a condition like keratoconus, all these barriers actually again come into play. So, the clinical gold standard for diagnosing keratoconus essentially entails us being able to map the curvature of the corneal surface using a technique known as corneal topography. So, here we either use something called as a Placido base, where you project a disc kind of structure onto the cornea and capture an image using tomographers, or you use certain other technology to map out the surface of the cornea, both the anterior and the posterior surface. But all these devices, by and large are non-portable and are expensive. And these are typically available again at secondary or tertiary eye hospitals. India is a land of diversity. We have some of the best health care in cities like Bangalore where we are sitting and doing this recording while you move about 150 to 200 kilometers away, it's a completely different world out there. The cost of each of these tests again, makes this diagnosis very inaccessible to large sections of population, not only in India but in similar middle and low income countries. And to add to this, you have the bogey of the pandemic. So, with COVID-19 in play the last two years with restrictions on travel, it has become very difficult for young children to actually undergo annual eye exams where we could have even proactively tried to pick up some of these conditions. Sridhar Vedantham: OK, alright, Mohit, let me bring you in here. I'm curious as to what Microsoft Research is doing as part of this particular research collaboration, right? Because keratoconus sounds very, very far afield from Microsoft Research's typical computer science focus. Mohit Jain: So, I think one of the key pillars of MSR India is societal impact. So, if we can develop a diagnostic tool which can save even a handful of children getting blind, we think it has huge societal impact and Microsoft Research India completely, I think, supports such kind of technological solutions. With respect to the computer science research lab, we have developed a solution which actually uses cutting edge AI, especially in the field of image processing and then also we have developed a full end to end system. So hence there are like enough computer science research problem, really hard ones, that we actually solve as part of this research collaboration. Sridhar Vedantham: OK, so that's a good lead into me to ask you to talk a little bit about the solution that's been developed here. Mohit Jain: So, I think the solution has actually 3 core components. So the first component is actually a Placido disc like what Dr. Kaushik said that like there has to be something which projects concentric rings over the cornea. So, we actually 3D printed a Placido disc. So, we actually attach that Placido to the back of a smartphone camera and then capture an image of the cornea with the Placido projected over the cornea of a human. And the second component we have is actually a smart phone app which has inbuilt AI in it. So, in real time it actually helps the person who is capturing the image to actually get a perfect image because I think one of the core design principles that we had while working on this was to make sure that anyone can use this app to actually diagnose. We don't want like medical technician to be only be able to use it. So, there is some kind of AI assistance to help capture perfect image of the eye. And the third then we have like an image processing pipeline which takes this captured image as input and converts that into corneal topography heat maps. So, basically it gives a curvature heat map, which tells you like what is the curvature at each point of the cornea, and that is the kind of output that you also get from a medical grade corneal topographer. Sridhar Vedantham: So, the way you explain it sounds very simple, but I'm sure there were a bunch of challenges, while you know, both Sankara and MSR was doing the research. Can you give me a sense of what kind of challenges you faced? Mohit Jain: Yes, yes, I think the most trickiest part of this project was to actually do it in a portable setting. So right now the corneal topographer, that is like a $10,000 device which is there in Sankara hospital. There is actually a headrest and a chin rest. So, basically your whole face like the patient face is very very stable and hence the image capture process is fairly easy. Apart from that the topographer has a lot of specific hardware. For example, it has a specific hardware to determine how far is the eye from the camera, so which is actually called as a working distance, and getting that parameter right is very crucial. Like even a few millimeters of actually predicting that value wrong can completely change the generated heat map. So, we have to actually design a very innovative solution to figure out this working distance directly just from the captured image and the second part was that, like we actually did a lot of iteration on the Placido disc and also on the AI assistance which was actually running on the smart phone to actually help capture the best image, even without any kind of a support system in place, like without any headrest or chin rest. Sridhar Vedantham: Dr. Kaushik was there anything you wanted to add to that in terms of challenges from a medical point of view? Dr. Kaushik Murali: So, from the medical point of view, we are people of habit. When I say that, there is certain things that we are comfortable about and certain things that puts us off. So, one of the key challenges we gave to the MSR team was saying that the interface and reports had to be similar to what we were used to seeing. So, I think the challenge also came to the team in terms of ensuring that the heat maps were similar to the heat maps that we were used to seeing using a regular topographer and how we actually were able to match with it. So, the minute we were able to get that kind of familiarity built in, we found our doctors also being able to accept it much better. And once that was done then automatically the learning curve that came in in terms of using the device or interpreting the images came down very very fast. So, we were able to adapt to this much faster. We were even able to get some of our colleagues from other units to read these heat maps that we generated, just to validate it. Because we were also concerned saying that when you are putting it out as a screening device you should end up overestimating the disease. Because there is an indirect cost to a person and imagine the psychological impact to a parent if you tell him your young child may have a possible problem. So we didn't want to do that, so we were very finicky about the validation. So, it went through multiple iterations almost to the effect that Mohit and his team could have lunch on a Thursday, only after they finished a call with us. (Laughs) Mohit Jain: To add to that, this is actually a very crucial point. Initially what we were thinking, so there are like these two values called as sensitivity and specificity. So just to give you some context here, sensitivity is actually if the person has keratoconus, are we able to diagnose it as keratoconus. So that's the sensitivity. Specificity is that if the person does not have Keratoconus are we actually even diagnosing that correctly? So, we were thinking that we need to get really high sensitivity. We cannot leave anyone who has keratoconus undiagnosed. But we can have low specificity that even someone who does not have keratoconus, we can say that he or she has keratoconus and still it's OK because then he or she will actually go to a doctor and get checked up, maybe for a second time and then it will be diagnosed that he or she does not have keratoconus. But Dr. Kaushik specifically was really against that. OK, so he actually made our problem statement harder, saying that we want both sensitivity and specificity to be above 92%, OK. Because he does not want like parents to be unnecessarily worrying that their kid who is like in his teens right now and he has like this very serious eye condition. So hence we actually have to like, as what Dr. Kaushik said, like you have to go through multiple iteration to even like get the specificity right. And right now, I think we are at a stage where we have like both the numbers which are above 94% for a small trial that we did with Sankara, with more than 100 patients, and in future we plan to actually extend that trial and like do it in many more patients. [Music] Sridhar Vedantham: A question for both you, Mohit, as well as Doctor Kaushik, so, whoever wants to answer it. You know, you just put out some numbers there in terms of percentages, right, to say that this solution works well, but typically these need to be tagged against some kind of industry benchmark or some kind of medical benchmark given the established machines and equipment already that are already being used, right? So how does this SmartKC stack up against those? Dr. Kaushik Murali: So once the MSR team had come up with a complete solution and they had tested in their lab the reliability of the solution, so to speak, with the images that they had with them, we then apply to our Ethics Committee for a prospective study. So, we enrolled subjects coming to our hospital, and we had them get their cornea image with the SmartKC as well as with the Placido based topography system that we have in our hospital that we would typically have used in any case. One index that the device that we use in the hospital uses to identify keratoconus, is an index called as the percentage probability of keratoconus, or the PPK value. This if it is more than 45% is supposed to indicate the presence of keratoconus. So, what we found was with the SmartKC, the sensitivity of PPK value was 94.1% and the specificity was 100%, which was pretty comparable to what we had with our other device which stood at about 94.1% sensitivity and 95.5% specificity. More importantly, whenever you use any device as a screening tool is how repeatable is it, and how is the inter-rater agreement. If two different people use the same device on the same person, are they actually reading it out the same. So again, in this we found those indices to be really, really high. So, there's something called as the Cohen's Kappa value. This was about 0.94 for our tool, which compared to 0.96 for the device that we have in the hospital. This essentially indicates a fair agreement between two experts diagnosing keratoconus based on the images that we are generating using the SmartKC. Sridhar Vedantham: Wow, that's impressive. Uh, I had another question. You know, whenever I went into an eye hospital, there always seemed to be somebody who is well trained as a technician operating various machines. How does it work with this? I mean do you need any specific training on SmartKC? How intensive is that and are there any particular type of people you look for or some kind of skill level in people who can operate a SmartKC unit? Dr. Kaushik Murali: So, currently most of the data that was collected has been done by our optometry interns at the Sankara College of Optometry, so the skill set that was required was not very high. Like Mohit mentioned earlier, there is some assistant in terms of even how you can capture an image. So, the eventual endpoint for us would be this being used at a peripheral vision center or at some Primary Health Center as a part of a school screening program where a lay person can pick up this device and actually capture an image and at least be able to counsel the person about them having to have a further examination. So, the training that would probably be required is largely in terms of what the condition that they are screening for and what the next action needs to be. it's more counseling skill I would say rather than anything really technical. The machine does at all. It gives them a heat map, it tells them what the value is, it kind of literally puts up a red flag saying “Boss, be careful, there is a problem here”. Sridhar Vedantham: So, I'm guessing that's all part of the technology that's been built into it, say you know various guardrails to ensure that whoever is operating it is doing it in the right way, Mohit? Mohit Jain: Yes, yes Sridhar. So, basically in the latest version of the app, what we have done is that like the operator, whoever is actually capturing the image, he or she doesn't even have to click the capture button. So, you just have to place the SmartKC on a patient eye and it automatically tries to align it appropriately with the eye and once the alignment is right, once the image does not have any kind of a blur and the focus is appropriate, the light is fine, it automatically captures three images. So, that actually makes the process really easy for the operator. And he or she needs to go through very minimal training to get up and running with the device. Sridhar Vedantham: Nice. And you know we have referred earlier to the cost of current machines that are there that are used in eye hospitals and so on, right? And one of the guiding principles behind developing SmartKC was for something to be portable, inexpensive and easy to use in the field. One thing that I don't think we've spoken about yet is actually how inexpensive SmartKC is, and I'm also curious to find out whether the equipment that you use needs to be high end. For example, do you need a high-end mobile phone to do it and how does the whole system work? Mohit Jain: Yes, so currently for developing our research prototype, we actually end up spending like almost like $33 is the amount that we are end up spending making the device, apart from the smartphone. The smartphone that we are using is a slightly high end one, so it is around like a $400 device that we have used for the current prototype. But moving ahead we are actually for the next round of data collection with Sankar Hospital, we are actually trying out with like three different devices and starting from like $100 device, $200 device and the $300 device, so that we can actually see that with whether it works on all the devices. However, based on our current work, we hypothesize that, actually, it can work on any standard smartphone. It just needs a decent camera. By the way, nowadays even the $100 device have like a 20-megapixel camera. So, I think that's already taken care by the by the most of the latest smartphone. So, I think yeah, it should ideally work in all of them, but we will only know for sure once we have the second round of testing. Sridhar Vedantham: Cool. Uh, so you know, given that you've put in so much work and you've come up with something that sounds like a fantastic solution, what kind of impact do you think a SmartKC can have or what kind of impact do you hope SmartKC will have? Mohit Jain: So right now, actually, we have discussed a few use cases with Dr. Kaushik, and I think the most interesting use case is what Dr. Kaushik initially referred to is the teacher use case. The biggest impact SmartKC could have is that, let's say, all the teachers in India, even the rural one, urban one, semi urban or even like low-income community even in urban India they have access to SmartKC. And every year maybe twice a year or thrice a year they screen every children in their school for keratoconus. And because the numbers are really high, the numbers are like two to three children out of everyone hundred children will have keratoconus, so with that in mind, we should be able to get like a few cases from every school. So, if these are diagnosed very early on, then there is a very very high likelihood that they could have been treated just by simple glasses or contact lens, and they don't have to go through surgery or corneal transplant or blindness, which is the worst-case situation. By the way, I think earlier when we are talking about corneal transplant, so globally 27% of the corneal transplant happens to actually fix keratoconus. So it is, it is a very deadly disease. Dr. Kaushik Murali: So, I'm going to take off on a tangent. I'm actually going to look beyond just this particular solution. So, although I am here representing Sankara at this podcast, a couple of my colleagues actually did a deep dive into this entire solution. Dr. Anand and Dr. Pallavi were there, as well as some of our faculty from the College of Optometry. What this project has actually impacted us is to think of how we can actually leverage technology. Sitting in an eye hospital, often we have ideas, but we have no clue whom to ask. But honestly, now we know that there is a team at MSR that we can reach out to saying that hey, here is a problem, we think this warrants attention. Do you think you guys can solve it? And we found that works really well. So, this ability to collaborate between complete extremes of people, one end you have medical specialists have no clue about what engineering is. Today I think Mohit knows more optometry than even I do. (Laughs) So they actually borrowed textbooks from us to read. So, this kind of a collaboration is, I think, a phenomenal impact that this project has brought together, and we hope that together we will be able to come up with few more solutions that can align with our founders' dream of eliminating needless blindness from India. Sridhar Vedantham: Nice, congratulations Mohit. Mohit Jain: Thank you. (Laughs). Sridhar Vedantham: I'll come to you for my next eye test. Dr. Kaushik Murali: You will soon start referring to him as Doctor Mohit. (Laughs) Sridhar Vedantham: All right. I think I've got all the information that I really wanted. But one thing is, you know, if people want to adopt SmartKC and they want to take it out there in the field, what do they need to do? And are there any particular requirements or criteria that they need to fulfil, etc? I mean, how do people get hold of this? Mohit Jain: So right now, we have actually made everything open source. So, even the 3D print for the Placido disc, the STL file of that is open source. So, anyone can download it and just like you take a printout, you can actually go to a makerspace and get a 3D print of that. Even the app which is actually AI assisted app which is running on the smartphone, we have only written it for an Android phone, so you can actually download it and you can install it on your Android phone and connect that SmartKC Placido attachment and can click an image of eye. The image processing pipelines code is also completely open source, so the selected image you can then run on it to actually generate corneal topography heat map. So, that is that is the current state. Going ahead we are actually putting everything on the cloud so that once you have the Placido disc and you capture an image, it automatically goes to the cloud and gives you the final output. Sridhar Vedantham: Excellent. So I will add links to various things onto the podcast page once we're done with this. Dr. Kaushik, any final thoughts before we close this podcast? Dr. Kaushik Murali: So quite often we look at challenges as challenges, but I think essentially this collaboration has looked at an opportunity and how we can actually work on it. All it required was to put some method to the madness and what came up as one discussion is today, I think, churned out into three different projects that are currently underway. So, this is something that is a potential. It would be lovely if similar technology companies can collaborate with medical institutions across India. We don't have to look elsewhere for solutions. It's all here. It's up to us to figure it out and run with it. Sridhar Vedantham: That's a great note to end the podcast on. So, once again thank you so much, Dr. Kaushik and Dr. Mohit. Thank you so much. (Laughs) Mohit Jain: Thank you, Sridhar. [Music ends]

Episode 3: The Incredible, Unbelievable Story of Phineas Gage

Neuroscience: Amateur Hour

Play Episode Listen Later Jan 6, 2022 19:43

This legend took a metal bar through the brain that took out 4% of his cerebral cortex and still retained the ability to move, speak, and live his life. The behavioral changes that occurred after his accident have fascinated neuroscientists for centuries and still remain a fascinating insight into the function of the prefrontal cortex today. If you have any comments, questions, concerns, queries, or complaints, please email me at NeuroscienceAmateurHour@gmail.com or DM me at @NeuroscienceAmateurHour on Instagram. Citations and relevant papers below: O'Driscoll, K., Leach, J., “‘No longer Gage': an iron bar through the head, early observations of personality change after injury to the prefrontal cortex, BMJ (1998). doi: 10.1136/bmj.317.7174.1673aSiddiqui, S., Chatterjee, U., Kumar, D., Siddiqui, A., Goyal, N., Neuropsychology of prefrontal cortex, Indian Journal of Psychiatry, Volume 50, Issue 3 (2008). doi: 10.4103/0019-5545.43634Harlow, JM, Passage of an iron rod through the head. Boston Med Surg Journal. (1848)Harlow JM, Recovery from the passage of an iron bar through the head, Publ Mass Med Soc, (1868). Hamilton, J., Why Brain Scientists are Still Obsessed with the Curious Case of Phineas Gage, NPR, Weekend Edition Sunday (2017). Demnasio, H., Grabowski, T., Frank, R., Galaburda, AM., Damasio, AR., The Return of Phineas Gage: Clues about the Brain from the Skull of a Famous Patient, Science, Vol. 264, Issue 5162 (May 20, 1994). Van Horn, JD., Irimia, A., Torgerson, C., Chambers, M., Kikinis, R., Toga, A., Mapping Connectivity Damage in the Case of Phineas Gage, PLoS ONE, Volume 7, Issue 5 (2012). https://doi.org/10.1371/journal.pone.0037454Support the show (https://www.patreon.com/neuroscienceamateurhour)

Episode 2: Neuroscience of Sexy Times

Neuroscience: Amateur Hour

Play Episode Listen Later Dec 30, 2021 14:14

Sex is a complex but inescapable part of our lives. Lots of people do it every day, it affects our advertisements, our clothing, even our interactions with other people. But have you ever wondered what's happening in your brain during sex? Tune in to learn a little bit about the brain regions, circuits, and neurotransmitters at play during sexy times. If you have any comments, questions, concerns, queries, or complaints, please email me at NeuroscienceAmateurHour@gmail.com or DM me at @NeuroscienceAmateurHour on Instagram. Citations and relevant papers below: Hellier et al., Female Sexual Behavior in Mice Controlled by Kisspeptin Neurons, Nature Communications (2018). Seok, J., Sohn, J., Neural Substrates of Sexual Desire in Individuals with Problematic Hypersexual Disorder, Frontiers in Behavioral Neuroscience (2015). Stahl, S., Illustrating the circuits of sexual desire, Journal of Clinical Psychiatry (2010). Yang, L., Comninos, A., Dhillo, W., Intrinsic links among sex, emotion, and reproduction, Cellular and Molecular Life Sciences (2018). Leuner, B., Glasper, E., Gould, E., Sexual Experience Promotes Adult Neurogenesis in the Hippocampus Despite an Initial Elevation in Stress Hormones, PloS One (2010). Baird, A., Sex and the Single Amygdala, Part 2 of your Sexiest Brain Bits, Psychology Today (2019). Micevych, P., Meisel, R., Integrating Neural Circuits Controlling Female Sexual Behavior, Frontiers in Systems Neuroscience (2017). https://doi.org/10.3389/fnsys.2017.00042Jennings, K., De Lecea, L., Neural and Hormonal Control of Sexual Behavior, Endocrinology, Volume 161, Issue 10 (2020). https://doi.org/10.1210/endocr/bqaa150Baird, A. et al., Neurological Control of human sexual behavior: insight from new lesion studies. Journal of Neurology, Neurosurgery, and Psychiatry, Volume 78, Issue 10, (2006). https://jnnp.bmj.com/content/78/10/1042Oei, N., Rombouts, S., Soeter, R., van Gerven, J., Both, S., Dopamine modulates reward system activity during subconscious processing of sexual stimuli, Neuropsychopharmacology, Volume 37 (2012). https://www.nature.com/articles/npp201219Magon, N., Kalra, S., The orgasmic history of oxytocin, love, lust and labor, Indian Journal of Endocrinology and Metabolism, (2011). 10.4103/2230-8210.84851Algoe, S., Kurtz, L., Grewen, K., Oxytocin and Social Bonds: The Role of Oxytocin in Perceptions of Romantic Partners' Bonding Behaviors, Psychological Science, Volume 28, Issue 12 (2017).Support the show (https://www.patreon.com/neuroscienceamateurhour)

Episode 9 - COVID-19 Series: Part 3 - Current Treatment Options

Network Five Emergency Medicine Journal Club

Play Episode Listen Later Oct 5, 2021 61:59

Theme: COVID-19. Participants: Dr Matthew O'Sullivan (infectious diseases specialist), Prof. Sanjay Swaminathan (immunologist), Dr George Zhou (intensivist), Ali Sayeed (ICU registrar), Dr James Tadros (ED consultant), Dr Pramod Chandru (ED consultant), Harry Hong, Samoda Wilegoda Mudalige, Shreyas Iyer, Kit Rowe, and Caroline Tyers.Discussion:Ansems, K., Grundeis, F., Dahms, K., Mikolajewska, A., Thieme, V., & Piechotta, V. et al. (2021). Remdesivir for the treatment of COVID-19. Cochrane Database Of Systematic Reviews, 2021(8). https://doi.org/10.1002/14651858.cd014962.Presenter - Ali Sayeed, ICU Registrar at Westmead Hospital.Summary: Remdesivir is a small molecule pro-drug that inhibits viral replication via its inhibition of RNA polymerase - In Australia, it has been provisionally approved by the TGA for its use in COVID-19. The theory behind using Remdesivir is really in the early stages of COVID-19 pneumonitis (by reducing the viral load and thereby preventing the augmentation of the inflammatory response). This was a systematic review with included meta-analyses looking at the use of Remdesivir in COVID-19 compared with placebo or standard care. It included only randomised control trials, with the primary outcomes being all-cause mortality, changes in clinical status (such as time to liberation from mechanical intervention) and adverse events. The 5 studies analysed for this review were: the Beigel study (ACTT-1 trial) which enrolled 1,000 patients, the Spinner trial which had 600 patients, the Wang trial with 230 patients, the Mahajan trial with 82 patients, and the WHO Solidarity trial with over 5,000 patients. Remdesivir was found to have little to no impact on all-cause mortality at 28 days. The duration to liberation from non-invasive and invasive mechanical ventilation was found to be 17 days in the Remdesivir group compared with 20 days in the control group in the Beigel study, and 7 days in the Remdesivir group compared with 15 days in the control group in the Wang study, although neither of these results were statistically significant. The Beigel study demonstrated a difference in time to recovery in the Remdesivir group compared with the placebo group, with a median difference of 5 days (however it is unclear whether this result was statistically significant). The significant heterogeneity in study protocols, methodology, subgroups and settings made it very difficult to compare these studies statistically. Take-Home Points: Remdesivir likely has very limited or no effect on hard outcomes in COVID-19 (in particular on mortality). The benefit of Remdesivir is not constant across disease severities; if there is a benefit it is likely to be a subset of patients (which appears to be those on low-flow oxygen). It does not appear to affect hospital length of stay (there is not sufficient evidence to suggest it does). All outcomes were based on low certainty evidence, and it is unlikely that there will be further evidence on Remdesivir alone to come, as most patients will be receiving combination therapy in ongoing studies. Of all the treatment modalities that we have for COVID-19, Remdesivir appears to be the one that has the least impact, but it was the one that was available first, and has very few side effects. At present in NSW, COVID-19 patients requiring oxygen are being treated with a combination of Dexamethasone, Remdesivir and Baracitinib (or Tocilizumab). References: Beigel JH, Tomashek KM, Dodd LE, Mehta AK, Zingman BS, Kalil AC, et al. Remdesivir for the treatment of COVID-19 – final report. New England Journal of Medicine 2020;383:1813-26.[DOI: 10.1056/NEJMoa2007764]. Spinner CD, Gottlieb RL, Criner GJ, Arribas Lopez JR, Cattelan AM, Soriano Viladomiu A, et al. Effect of remdesivirvs standard care on clinical status at 11 days in patientswith moderate COVID-19: a randomised clinical trial. JAMA2020;324(11):1048-57. [DOI: 10.1001/jama.2020.16349] [PMID:32821939]. Wang Y, Zhang D, Du G, Du R, Zhao J, Jin Y, et al. Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial. The Lancet2020;395(10236):1569-78. [CLINICALTRIALS.GOV: NCT04257656][DOI: 10.1016/s0140-6736(20)31022-9]. Mahajan L, Singh AP, GiSy. Clinical outcomes of using Remdesivir in patients with moderate to severe COVID-19: a prospective randomised study. Indian Journal of Anaesthesia2021;65:41-6. [DOI: 10.4103/ija.IJA_149_21]. WHO Solidarity Trial Consortium. Repurposed antiviral drugs for COVID-19 - interim WHO solidarity trial results. New England Journal of Medicine 2021;384(8):497-511. [CLINICALTRIALS.GOV:NCT04315948] [DOI: 10.1056/NEJMoa2023184] [EUCTR:EUCTR2020-001366-11] [ISRCTN: ISRCTN83971151]. Living Guidelines [Internet]. Caring for people with COVID-19. 2021 [cited 16 September 2021]. Available from: https://covid19evidence.net.au/#living-guidelines. The RECOVERY Collaborative Group. Dexamethasone in Hospitalized Patients with Covid-19. New England Journal of Medicine [Internet]. 2021 [cited 16 September 2021];384(8):693-704. Available from: https://www.nejm.org/doi/full/10.1056/NEJMoa2021436. Kalil AC, Patterson TF, Mehta AK, Tomashek KM, et al. Baricitinib plus Remdesivir for Hospitalized Adults with COVID-19. N Engl J Med 2021; 384:795-807. Gupta A, Gonzalez-Rojas Y, Juarez E, Crespo Casal M, Moya J, Falci DR, Sarkis E, Solis J, Zheng H, Scott N, Cathcart AL, Hebner CM, Sager J, Mogalian E, Tipple C, Peppercorn A, Alexander E, Pang PS, Free A, Brinson C, Aldinger M, Shapiro AE. Early COVID-19 Treatment with SARS-CoV-2 Neutralizing Antibody Sotrovimab [Internet]. medRxiv; May 2021 [cited 16 September 2021]. Available from: https://www.medrxiv.org/content/10.1101/2021.05.27.21257096v1. Tomazini B, Maia I, Cavalcanti A, Berwanger O, Rosa R, Veiga V et al. Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19. JAMA [Internet]. 2020 [cited 16 September 2021];324(13):1307. Available from: https://jamanetwork.com/journals/jama/fullarticle/2770277. Hasan MJ, Rabbani R, Anam AM, Huq SMR, Polash MMI, Nessa SST, Bachar SC. Impact of high dose Baracitinib in severe COVID-19 pneumonia: a prospective cohort study in Bangladesh. BMC Infect Dis. May 2021; 21(1): 427. Available from: https://pubmed.ncbi.nlm.nih.gov/33962573/. Kit's Corner Signbank [Internet]. Auslan.org.au. 2021 [cited 01 October 2021]. Available from: https://www.auslan.org.au/dictionary/words/COVID-19-1.html. Credits:This episode was produced by the Emergency Medicine Training Network 5 with the assistance of Dr Kavita Varshney and, Deepa Dasgupta. Music/Sound Effects Angel by Ikson | https://youtube.com/ikson, Music promoted by https://www.free-stock-music.com. Blue Sweater by RYYZN | https://soundcloud.com/ryyzn, Music promoted by https://www.free-stock-music.com, Creative Commons Attribution 3.0 Unported License, https://creativecommons.org/licenses/by/3.0/deed.en_US. Nightswim by Scandinavianz | https://soundcloud.com/scandinavianz, Music promoted by https://www.free-stock-music.com, Creative Commons Attribution 3.0 Unported License, https://creativecommons.org/licenses/by/3.0/deed.en_US. Misfits (Instrumental) by RYYZN | https://soundcloud.com/ryyzn, Music promoted by https://www.free-stock-music.com, Creative Commons Attribution 3.0 Unported License, https://creativecommons.org/licenses/by/3.0/deed.en_US. Sound effects from https://www.free-stock-music.com. Thank you for listening!Please send us an email to let us know what you thought.You can contact us at westmeadedjournalclub@gmail.com.You can also follow us on Facebook, Instagram, and Twitter!See you next time,Caroline, Kit, Pramod, Samoda, and Shreyas.~

Vaccinating against COVID-19 How did we get so many vaccines so fast

covid-19 indian vaccines bioscience medical ethics vaccinating ashoka university indian journal

Play Episode Listen Later Sep 30, 2021 16:39

The Indian government is gearing up for mass COVID-19 vaccinations. The question foremost on everyone’s minds are how were they developed so fast. The first episode of this two-part series for the Suno India Show gives a step-by-step explanation on vaccine development and what is different this time round. For this show we feature the expert voices of Dr Shaheed Jameel, currently the director of the Trivedi School of Biosciences at Ashoka University, and Dr Amar Jesani, an expert bioethicist and teacher who has founded the prestigious journal, Indian Journal of Medical Ethics. Also Listen “Vaccinating against COVID-19: Has the vaccine development been a fair and transparent process?“See sunoindia.in/privacy-policy for privacy information.

Vaccinating against COVID-19 Has the vaccine development been a fair and transparent process

Play Episode Listen Later Sep 30, 2021 27:10

This is the second episode in the two-part series on developing COVID-19 vaccines for the Suno India show. In the first episode of the series, we discussed the different stages of clinical trials and how the vaccines were developed so fast. In the second part, we are addressing key concerns about the cynicism around vaccine development. What are the legal processes involved in clearing the vaccines for mass vaccination in India? Were the vaccine trials fair and ethical? Is all the relevant information related to the vaccine development shared with the public? For this episode, Menaka Rao spoke to Dr Amar Jesani, an expert bioethicist and teacher who has founded the prestigious journal, Indian Journal of Medical Ethics and advocate Murali Neelakantan, an expert in healthcare laws and drug development in India. Also listen “Vaccinating against COVID-19: How did we get so many vaccines so fast?"See sunoindia.in/privacy-policy for privacy information.

covid-19 vaccines transparent medical ethics vaccinating vaccine development indian journal suno india

Why are most of the medicines being approved for COVID-19 so expensive

covid-19 families expensive approved rs medicines cancer patients medical ethics indian journal

Play Episode Listen Later Sep 25, 2021 28:26

There is an urgent need to find a cure for COVID-19. Old drugs that have been developed and approved for one disease are now being evaluated to see if they can be used to reduce the severity and to bring down mortality of this new disease. Some drugs have been proven to be effective. Some have been found to have limited impact. Yet others have not been proven effective but are widely used anyway. All but one of these drugs is priced in the tens of thousands of rupees per course of treatment out of reach of most patients of COVID-19. Add the charges for other drugs and for the hospital. Families of patients are looking at bills of lakhs and lakhs of rupees. The bulk of people falling ill with COVID-19 are the poor and most vulnerable to infection because of their cramped living conditions, or because their work requires interaction with the public, such as frontline healthcare workers, bus conductors, shopkeepers, street vendors. But their doctors have told them that these drugs work. So they are among those standing in long lines outside pharmacies, for medicines which cost Rs 30,000 upwards. In this episode, Sandhya Srinivasan, consulting editor of the Indian Journal of Medical Ethics talks to Advocate Veena Johari who has worked for decades on legal action and has recently written a letter on behalf of the Cancer Patients’ Aid Association to revoke a patent on Remdesivir. Download – TranscriptSee sunoindia.in/privacy-policy for privacy information.

The need for evidence-based medicine in treating COVID-19

covid-19 treating medical science medical ethics evidence based medicine treating covid indian journal

Play Episode Listen Later Sep 25, 2021 48:14

A number of old drugs approved for other diseases are being “repurposed” and tested for their safety and efficacy in COVID-19, in systematic clinical trials. They have emergency approval for use in COVID-19, but most are not yet proven for this use. Some drugs have received approval without adequate testing. Other drugs are being used without getting approval for use in COVID-19. All these drugs are being prescribed widely by doctors, outside of clinical trials. In this episode, Sandhya Srinivasan, consulting editor for the Indian Journal of Medical Ethics spoke with Dr SP Kalantri, director professor of medicine at the Mahatma Gandhi Institute of Medical Sciences, Sewagram, and medical superintendent of the Kasturba Hospital there. One focus of his work has been the epidemiology of chronic diseases at the primary and secondary levels.See sunoindia.in/privacy-policy for privacy information.

Year in Infection Control - papers selected by Prof Andreas Voss at ICPIC 2021

Infection Control Matters

Play Episode Listen Later Sep 21, 2021 22:50

In this final episode at ICPIC 2021 (Geneva), Martin Kiernan talks to Professor Andreas Voss from the Radboud University Medical Centre (Radboudumc) and Canisus-Wilhelmina Ziekenhuis in the Netherlands. Andreas is always a sought after speaker for his engaging style whilst getting to the heart of the matter. To get the most from this podcast, you might need to look at the papers we mention below. Endoscopes Benowitz I, Moulton-Meissner HA, Epstein L, Arduino MJ. Gastrointestinal Flexible Endoscopes: Infection Control Risks, Lessons Learned from Outbreaks, and Centers for Disease Control and Prevention Guidance. Gastrointestinal Endoscopy Clinics of North America. 2020;30(4):723-33 https://www.sciencedirect.com/science/article/abs/pii/S1052515720300702?via%3Dihub Sinks De Geyter D, Blommaert L, Verbraeken N, Sevenois M, Huyghens L, Martini H, et al. The sink as a potential source of transmission of carbapenemase-producing Enterobacteriaceae in the intensive care unit. Antimicrob Resist Infect Control. 2017;6:24. https://www.ncbi.nlm.nih.gov/pubmed/34111433 Decreased other infections (STD and Norovirus) Nelson B. The positive effects of covid-19. BMJ. 2020;369:m1785. http://www.bmj.com/content/369/bmj.m1785.abstract Bruggink LD, Garcia-Clapes A, Tran T, Druce JD, Thorley BR. Decreased incidence of enterovirus and norovirus infections during the COVID-19 pandemic, Victoria, Australia, 2020. Commun Dis Intell (2018). 2021 Jan 29;45. doi: 10.33321/cdi.2021.45.5. PMID: 33573536. Impact on ocular health Bahkir, Fayiqa Ahamed; Grandee, Srinivasan Subramanian Impact of the COVID-19 lockdown on digital device-related ocular health, Indian Journal of Ophthalmology: November 2020 - Volume 68 - Issue 11 - p 2378-2383 doi: 10.4103/ijo.IJO_2306_20 Dog-assisted therapy Edner A, Lindstrom-Nilsson M, Melhus A. Low risk of transmission of pathogenic bacteria between children and the assistance dog during animal-assisted therapy if strict rules are followed. J Hosp Infect. 2021;115:5-9. https://www.journalofhospitalinfection.com/article/S0195-6701(21)00178-X/fulltext Lace up masks Wang X, Lin F, Wang Z, Hu J, Li X, Zhu B, et al. The defects of lace-up surgical masks and related solutions in operating rooms. J Hosp Infect. 2021;115:64-70. https://www.journalofhospitalinfection.com/article/S0195-6701(21)00237-1/fulltext#relatedArticles Migrane and mask wearing Bharatendu C, Ong JJY, Goh Y, Tan BYQ, Chan ACY, Tang JZY, et al. Powered Air Purifying Respirator (PAPR) restores the N95 face mask induced cerebral hemodynamic alterations among Healthcare Workers during COVID-19 Outbreak. J Neurol Sci. 2020;417:117078. https://www.jns-journal.com/action/showPdf?pii=S0022-510X%2820%2930415-9 A nose for pneumonia Chen, C.-Y., Lin, W.-C. & Yang, H.-Y. Diagnosis of ventilator-associated pneumonia using electronic nose sensor array signals: solutions to improve the application of machine learning in respiratory research. Respir Res 2020;21:45 (2020). https://doi.org/10.1186/s12931-020-1285-6 Social media for epidemiologists Hammer CC, Boender TS, Thomas DR. Social media for field epidemiologists (#SoMe4epi): How to use Twitter during the #COVID19 pandemic. Int J Infect Dis. 2021. https://linkinghub.elsevier.com/retrieve/pii/S1201-9712(21)00437-9 Use of Emoji in communication Lotfinejad, N., Assadi, R., Aelami, M. H. & Pittet, D. Emojis in public health and how they might be used for hand hygiene and infection prevention and control. Antimicrob Resist Infect Control 2020;9:27. https://doi.org/10.1186/s13756-020-0692-2 On Call IPC Services Humphreys H. Infection prevention and control advice out-of-hours. J Hosp Infect. 2020;105(4):795-6. https://www.journalofhospitalinfection.com/article/S0195-6701(20)30262-0/fulltext Handshake/Fist Bump Sklansky M, Nadkarni N, Ramirez-Avila L. Banning the handshake from the health care setting. JAMA. 2014;311(24):2477-8. https://jamanetwork.com/journals/jama/article-abstract/1873637 Mela S, Whitworth DE. The fist bump: a more hygienic alternative to the handshake. Am J Infect Control. 2014;42(8):916-7. http://www.ncbi.nlm.nih.gov/pubmed/25087144 Elbow or hand Liu H, Gao L, Sun C. Elbow instead of hand: is it more helpful or harmful? J Public Health (Oxf). 2020. https://www.ncbi.nlm.nih.gov/pubmed/32529204

Year in Infection Control - papers selected by Prof Andreas Voss at ICPIC 2021

Infection Control Matters

Play Episode Listen Later Sep 21, 2021 22:50

In this final episode at ICPIC 2021 (Geneva), Martin Kiernan talks to Professor Andreas Voss from the Radboud University Medical Centre (Radboudumc) and Canisus-Wilhelmina Ziekenhuis in the Netherlands. Andreas is always a sought after speaker for his engaging style whilst getting to the heart of the matter. To get the most from this podcast, you might need to look at the papers we mention below. Endoscopes Benowitz I, Moulton-Meissner HA, Epstein L, Arduino MJ. Gastrointestinal Flexible Endoscopes: Infection Control Risks, Lessons Learned from Outbreaks, and Centers for Disease Control and Prevention Guidance. Gastrointestinal Endoscopy Clinics of North America. 2020;30(4):723-33 https://www.sciencedirect.com/science/article/abs/pii/S1052515720300702?via%3Dihub Sinks De Geyter D, Blommaert L, Verbraeken N, Sevenois M, Huyghens L, Martini H, et al. The sink as a potential source of transmission of carbapenemase-producing Enterobacteriaceae in the intensive care unit. Antimicrob Resist Infect Control. 2017;6:24. https://www.ncbi.nlm.nih.gov/pubmed/34111433 Decreased other infections (STD and Norovirus) Nelson B. The positive effects of covid-19. BMJ. 2020;369:m1785. http://www.bmj.com/content/369/bmj.m1785.abstract Bruggink LD, Garcia-Clapes A, Tran T, Druce JD, Thorley BR. Decreased incidence of enterovirus and norovirus infections during the COVID-19 pandemic, Victoria, Australia, 2020. Commun Dis Intell (2018). 2021 Jan 29;45. doi: 10.33321/cdi.2021.45.5. PMID: 33573536. Impact on ocular health Bahkir, Fayiqa Ahamed; Grandee, Srinivasan Subramanian Impact of the COVID-19 lockdown on digital device-related ocular health, Indian Journal of Ophthalmology: November 2020 - Volume 68 - Issue 11 - p 2378-2383 doi: 10.4103/ijo.IJO_2306_20 Dog-assisted therapy Edner A, Lindstrom-Nilsson M, Melhus A. Low risk of transmission of pathogenic bacteria between children and the assistance dog during animal-assisted therapy if strict rules are followed. J Hosp Infect. 2021;115:5-9. https://www.journalofhospitalinfection.com/article/S0195-6701(21)00178-X/fulltext Lace up masks Wang X, Lin F, Wang Z, Hu J, Li X, Zhu B, et al. The defects of lace-up surgical masks and related solutions in operating rooms. J Hosp Infect. 2021;115:64-70. https://www.journalofhospitalinfection.com/article/S0195-6701(21)00237-1/fulltext#relatedArticles Migrane and mask wearing Bharatendu C, Ong JJY, Goh Y, Tan BYQ, Chan ACY, Tang JZY, et al. Powered Air Purifying Respirator (PAPR) restores the N95 face mask induced cerebral hemodynamic alterations among Healthcare Workers during COVID-19 Outbreak. J Neurol Sci. 2020;417:117078. https://www.jns-journal.com/action/showPdf?pii=S0022-510X%2820%2930415-9 A nose for pneumonia Chen, C.-Y., Lin, W.-C. & Yang, H.-Y. Diagnosis of ventilator-associated pneumonia using electronic nose sensor array signals: solutions to improve the application of machine learning in respiratory research. Respir Res 2020;21:45 (2020). https://doi.org/10.1186/s12931-020-1285-6 Social media for epidemiologists Hammer CC, Boender TS, Thomas DR. Social media for field epidemiologists (#SoMe4epi): How to use Twitter during the #COVID19 pandemic. Int J Infect Dis. 2021. https://linkinghub.elsevier.com/retrieve/pii/S1201-9712(21)00437-9 Use of Emoji in communication Lotfinejad, N., Assadi, R., Aelami, M. H. & Pittet, D. Emojis in public health and how they might be used for hand hygiene and infection prevention and control. Antimicrob Resist Infect Control 2020;9:27. https://doi.org/10.1186/s13756-020-0692-2 On Call IPC Services Humphreys H. Infection prevention and control advice out-of-hours. J Hosp Infect. 2020;105(4):795-6. https://www.journalofhospitalinfection.com/article/S0195-6701(20)30262-0/fulltext Handshake/Fist Bump Sklansky M, Nadkarni N, Ramirez-Avila L. Banning the handshake from the health care setting. JAMA. 2014;311(24):2477-8. https://jamanetwork.com/journals/jama/article-abstract/1873637 Mela S, Whitworth DE. The fist bump: a more hygienic alternative to the handshake. Am J Infect Control. 2014;42(8):916-7. http://www.ncbi.nlm.nih.gov/pubmed/25087144 Elbow or hand Liu H, Gao L, Sun C. Elbow instead of hand: is it more helpful or harmful? J Public Health (Oxf). 2020. https://www.ncbi.nlm.nih.gov/pubmed/32529204

Episode 7: Laser vs IPL - Hair Removal

TY Skin

Play Episode Listen Later Jul 20, 2021 54:36

Welcome to Episode 7 of TY Skin, where Tonaya and Yianni go LIVE on Stereo! They discuss their current thoughts on the Melbourne Lockdown 5.0, what a laser and IPL machine is and how they treat hair on a cellular level and on a naked eye level. Misconceptions on laser hair removal are demistified, and what someone can expect to see after a treatment is discussed. Make sure to follow us to stay up to date on our podcasts. If you enjoyed this episode, please make sure to give us a review on Apple Podcasts Follow us on the Stereo app to keep up to date for when we go live again: https://stereo.com/yian.m , https://stereo.com/tonayabarton ------------------------------------------------------------------ Welcome to TY Skin. We are Tonaya and Yianni: Fourth year Dermal Clinic students interested in everything and anything skin. We are here to unveil, debunk, discuss and divulge the dermal world. If you would like to submit an anonymous question for us to answer, please use the following Google Form: https://forms.gle/agF1fvfYgBTgyjz16 Disclaimer: We do our best to research and give our clinically-thought opinions on dermal-related treatments, products and ideas. Topics discussed are subject to change and all things discussed should be taken as discourse and not advice for listeners. Ensure to do independent research and make the best choice for yourself with the help of health professionals, and qualified Dermal Clinicians/Therapists TY Skin podcast is being held on the lands of the Wurunjeri people and I wish to acknowledge them as Traditional Owners. We would also like to pay my respects to their Elders, past and present, and Aboriginal Elders of other communities who may be here today. ------------------------------------------------------------------ Shownotes: Desired endpoint of laser hair removal: https://fi.realself.com/545/4496cb412d1add3a9f40759a81d1a215/4/6/1/userimage-1635496.jpg Undesired endpoint of laser hair removal: https://dermnetnz.org/assets/Uploads/procedures/laser-hypopigmentation__WatermarkedWyJXYXRlcm1hcmtlZCJd.jpg https://imageresizer.static9.net.au/fs3thsZDJX3sjpSLINqALVK3jCI=/800x0/https%3A%2F%2Fprod.static9.net.au%2Ffs%2Fb2b0f024-a899-451d-a9d2-44908ebd6bc7 ------------------------------------------------------------------ Journal Articles for Further Research: Goldberg, D. J. (2012). Current Trends in Intense Pulsed Light. The Journal of Clinical and Aesthetic Dermatology, 5(6), 45-53. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390232/ Patil, U. A., & Dhami, L. D. (2008). Overview of lasers. Indian Journal of Plastic Surgery, 41, S101–S113. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825126/ Laser Fitzpatrick Skin Type Recommendations. Stat Pearls. https://www.ncbi.nlm.nih.gov/books/NBK557626/

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Episode 57 - Penile Enhancement and ED

Breaking Bad Science

Play Episode Listen Later Jul 11, 2021 46:11

We'd love to hear from you (feedback@breakingbadscience.com)Look us up on social media Facebook: https://www.facebook.com/groups/385282925919540Instagram: https://www.instagram.com/breakingbadsciencepodcast/Website: http://www.breakingbadscience.com/Patreon: https://www.patreon.com/breakingbadscienceIn today's world of body positivity and cosmetic surgery it seems like something has been left out on both fronts. Male enhancement. How has the penis become a central focus of society but also taboo to talk about? Everyone has things we would like to change about ourselves but what works and what's effectively just snake oil when it comes to male enhancement. Join Shanti and a bit of a surprise host as we talk about the uncomfortable but important topic of penile augmentation.ReferencesDillon, B., et. al.; Penile Size and Penile Enlargement Surgery: A Review. International Journal of Impotence Research. 22-May-2008. 20 (519 - 529). Doi: https://doi.org/10.1038/ijir.2008.14Mayo Clinic Staff. Penis-Enlargement Products: Do They Work?. Mayo Clinic. 03-Jun-2020. https://www.mayoclinic.org/healthy-lifestyle/sexual-health/in-depth/penis/art-20045363Burry, M.; What Is a Micropenis? - and How It Does (and Doesn't) Affect Sex. Health. 14-Sep-2020. https://www.health.com/condition/sexual-health/micropenis-sexArackal, B., Benegal, V.; Prevalence of Sexual Dysfunction in Male Subjects with Alcohol Dependence. Indian Journal of Psychiatry. Apr-2007. 49:2 (109 - 112). Doi: https://doi.org/10.4103/0019-5545.33257Shah, J., Christopher, N.; Can Shoe Size Predict Penile Length?. British Journal of Urology International. Oct-2002. 90:6 (586 - 587). Doi: https://doi.org/10.1046/j.1464-410x.2002.02974.xIliades, C.; What's Wrong With Long-Lasting Erections. Everyday Health. 08-Mar-2012. https://www.everydayhealth.com/erectile-dysfunction/whats-wrong-with-long-lasting-erections.aspxArmstrong, J., et. al.; Impact of Anabolic Androgenic Steroids on Sexual Function. Translational Andrology and Urology. Jun-2018. 7:3 (483 - 489). Doi: https://doi.org/10.21037/tau.2018.04.23Goldstein, I., et. al.; The Serendipitous Story of Sildenafil: An Unexpected Oral Therapy for Erectile Dysfunction. Sexual Medicine Reviews. Jan-2019. 7:1 (115 - 128). Doi: https://doi.org/10.1016/j.sxmr.2018.06.005Support the show (https://www.patreon.com/breakingbadscience?fan_landing=true)

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Is it right to dismiss AYUSH?

mental health phd religion spirituality atlantic psychiatry retrieved abraham verghese indian journal

Play Episode Listen Later Jun 30, 2021 29:40

In May this year, Indian Medical Association officials filed a police complaint against yoga guru Baba Ramdev for making defamatory statements about allopathic doctors. Just a few months before that, the association was protesting against a Central government notification allowing Ayurveda postgraduates to conduct some surgical procedures. In the meanwhile, the government has been promoting traditional medicine products, including Coronil for immunity against COVID-19 for which there is no evidence. Traditional medicine, be it Ayurveda or Homeopathy, is very popular in India. In this episode, Suno India's Padmapriya DVL and Menaka Rao report on the various aspects related to the debate related to traditional medicine, from the safety of drugs to the legitimacy of these traditional forms of medicine. This episode features Dr Ritu Priya Mehrotra, professor at the Centre of Social Medicine and Community Health, Jawaharlal Nehru University, Delhi, Dr Sanjay Nagral, a Mumbai-based gastrointestinal and liver surgeon and on the editorial board of Indian Journal of Medical Ethics, and Dr Cyriac Abby Philips, a Kochi-based hepatologist who has been revealing how unregulated traditional medicines are causing liver injuries in people. Additional reading: Union Budget 2020-21 places the AYUSH Sector on a sustainable path of growth, say sectoral The Cure – fiftytwo.in Traditional Indian Medicine Guidelines To Build COVID Immunity Published General guidelines for Safety/toxicity evaluation of Ayurvedic formulations Can Ayush cure Covid? AYUSH for COVID-19: Science or Superstition? Priya R, Sujatha V – Indian J Public Health Research conducted by Kovai scientists on rheumatic patients shortlisted for prestigious award | Coimbatore News Clinical outcomes histopathological patterns and chemical analysis of Ayurveda and herbal medicines associated with severe liver injury- A single center experience from Southern India See sunoindia.in/privacy-policy for privacy information.

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694 - Spirituality, Religion, & Mental Health

Tiny Leaps, Big Changes

Play Episode Listen Later Apr 14, 2021 16:25

In this episode, we look at the mental health benefits of religion and spirituality. Hosted By: Gregg Clunis | https://www.instagram.com/greggclunis/ Instagram: http://instagram.com/tinyleaps Twitter: http://twitter.com/tinyleaps Website: http://tlbc.co/tiny-leaps-big-changes Resources: Caroline Kitchener. (2018). What It Means To Be Spiritual But Not Religious. The Atlantic. https://www.theatlantic.com/membership/archive/2018/01/what-it-means-to-be-spiritual-but-not-religious/550337/. Simon Dein, PhD. (2010). Religion, Spirituality, and Mental Health. Psychiatric Times. Retrieved from https://www.psychiatrictimes.com/view/religion-spirituality-and-mental-health. Abraham Verghese. (2008). Spirituality and Mental Health. Indian Journal of Psychiatry. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755140 --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

Disputes Digest #23 - March10, 2021

Tales of The Tribunal

Play Episode Listen Later Mar 10, 2021 8:19

Follow us on LinkedIn: https://www.linkedin.com/company/40833847/admin/ Check out or new website: TalesOfTheTribunal.com For Feedback, comments or submissions contact TalesOfTheTribunal@Gmail.com News: Malawi join the New York Convention, Here. German Energy in ISDS Claims, Here. ICDR Rule Changes, Here. This story .Sucks, Here. Singapore and Indonesia BIT, Here. Opportunities: EFILA, Calls for Papers, Here. American University, Call for Papers, Here. Call for Papers by Indian Journal of Arbitration Law [IJAL]: Submit by Mar 31, Here. Clifford Chance Posting, Here. Lalive Posting, Here. Events/Webinars: ICC YAF: Women in Arbitration, Here. Moot Alumni Association, Here.

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The Feminist City, Ep. 6 - Shifting Away from Criminal Approaches and Carcerality for Gender Justice

Vidhi Centre for Legal Policy's Podcast

Play Episode Listen Later Feb 17, 2021 46:48

Producer and Host: Sneha Visakha; Intro Music: Wehrmut by Godmode; Outro Music: Opheliea's Blues by Audionautix Trigger Warning: references to violence against women, sexual harassment, carcerality, and extra-judicial violence Legal approaches to women's safety have tended to be highly dominated by discussions around criminal justice and carcerality. In this episode, Sneha Visakha is in conversation with Alok Prasanna Kumar about why tackling violence against women must shift away from criminal approaches to bringing about structural changes towards correcting gendered power imbalance in society - making questions of municipal law, education and social and economic justice mechanisms sites for feminist legal intervention. They discuss the contrast in the State's paternalistic protectionism towards women's safety versus the targeting of young women by the State's criminal apparatus, changing goals of feminist movements, varied state responses to violence against women belonging to marginalised communities, about carcerality, trauma and why the criminal justice system doesn't seem to work for women. Readings: Making a Feminist City - Planning Safety and Autonomy in the City, Sneha Visakha https://vidhilegalpolicy.in/research/making-a-feminist-city-planning-safety-and-autonomy-for-women/ Power, An open letter to the Supreme Court changed the way many Indians thought about women's rights, Sarita Santhoshini, FiftyTwo.in https://fiftytwo.in/story/power/ The Unconstitutionality of the Marital Rape Exemption in India, Agnidipto Tarafder and Adrija Ghosh, Oxford Human Rights Hub https://bit.ly/3qzaFmo Submission to UNSR on Violence Against Women on Thematic Report on Rape, Sandra Fredman, Anjali Rawat, Aradhana Cherupara Vadekkethil and Meghan Campbell, Oxford Human Rights Hub https://ohrh.law.ox.ac.uk/publications/submission-to-unsr-on-violence-against-women-on-thematic-report-on-rape/ Feminism in Legal Education, Catherine Mackinnon; Feminist Legal Theories, Summary http://www.austlii.edu.au/au/journals/LegEdRev/1989/7.html https://cyber.harvard.edu/bridge/CriticalTheory/critical3.txt.htm The “Public Secret” of Torture, Its Dimensions and Context, In conversation with Jinee Lokaneeta, Indian Journal of Law and Public Policy https://ijlpp.com/in-conversation-with-prof-jinee-lokaneeta-the-public-secret-of-torture-its-dimensions-and-context/ On sexual harassment, why complain, strategic inefficiency, nodding as a non-performative, in the thick of it, complaint and survival, Sara Ahmed, Feminist Killjoys https://feministkilljoys.com/2015/12/03/sexual-harassment/ Book Review: Sheela Reddy's Mr And Mrs Jinnah: The Marriage That Shook India, LiveMint https://www.livemint.com/Leisure/5ZctNxvhWGgJWAIfWjr5MM/Book-review-Mr-And-Mrs-Jinnah.html Most Harassment of Transgender People is by Police, Times of India https://timesofindia.indiatimes.com/city/chennai/Police-harass-transgenders-most-says-study/articleshow/51869919.cms One in Every Three Under-Trial Prisoners in India Is Either SC or ST: Study, The Wire https://thewire.in/rights/one-in-every-three-under-trial-prisoners-in-india-is-either-sc-or-st-study People of denotified tribes continue to bear the burden of an unjust colonial past, Nikita Sonavane , Srujana Bej , Ameya Bokil, The Indian Express https://indianexpress.com/article/opinion/people-of-denotified-tribes-continue-to-bear-the-burden-of-an-unjust-colonial-past-7095613/ What to Say to Your Daughter About Campus Sexual Assault, Nicole Bedera, Slate https://slate.com/human-interest/2020/03/daughter-advice-sexual-assault-college.html A detailed list of readings is here: https://vidhilegalpolicy.in/podcasts/the-feminist-city-trailer/shifting-away-from-criminal-approaches-and-carcerality-for-gender-justice/

power law state police blues supreme court shifting criminals feminism context feminists rape approaches indians torture autonomy violence against women god mode transgender people legal education gender justice sara ahmed indian journal nicole bedera feminist city catherine mackinnon

Come On Vaccine! Vaccine Hesitancy & You

Conspiracy Clearinghouse

Play Episode Listen Later Feb 17, 2021 52:58

EPISODE 26 | Come On Vaccine! Vaccine Hesitancy & YouScience marches on, eradicating debilitating diseases (among other things). However, there have always been some who are skeptical, or even downright hostile, to this. There are lots of reasons: maybe God wants your kid to get sick, the ingredients used are harmful and/or weird, or they have terrible side effects, like giving children autism; turning them into half-man, half-cow hybrids or making making males become homosexuals. Or maybe there are teeny, tiny mind control devices in them.Or maybe all of these things are true. When you decide that science doesn't matter, and there's no such things as a fact, it's sort of a free for all of superstition and suspicion.SECTIONS02:00 - A quick overview of the situation04:03 - Don't Have a Cow! The smallpox vaccine starts it all08:12 - The Hospital of Dr. Moreau - Benjamin Moseley & others 11:04 - DPT (diphtheria, pertussis [whooping cough] & tetanus) - Vaccine Roulette & Dravet Syndrome15:01 - How to Make a Vaccine18:39 - The 'Vid - How we got vaccines so fast22:16 - MMR (measles, mumps, and rubella [German measles]) - (Former Dr.) Andrew Wakefield & the seeds of the modern anti-vax movement25:23 - Pointing fingers at anti-vax celebrities - a not-quite-complete list28:55 - Tweedle-dee's Logic - Some reasons for vaccine hesitancy29:51 - Bubble, Bubble, Toil and Trouble - Ingredients - Icky, weird, deadly stuff33:19 - Heard of Herd Immunity? - A little knowledge is a dangerous thing36:11 - Mother Nature Knows Best - Post-modern snake oil37:12 - Big Pharma Wants You - It's all about the Benjamins38:39 - Cloud-Cuckoo Land - The "out there" conspiracy theories & truly spotty logic40:47 - Repercussions - Vaccine hesitancy affects us all45:13 - Cutting Through the Noise - 18 steps for talking to the vaccine hesitant Music by Fanette RonjatMore on this topic:Vaccine Hesitancy: Causes, Consequences, and a Call to Action in the American Journal of Preventative MedicineThe golden age of anti-vaccine conspiracies in GERMSAnti-Vaccine and COVID-19 Conspiracy Theories: A Perfect Storm in Psychology TodayThe 200-Year History of the Anti-Vaxxer Movement: From 'Cowpox Face' to Autism Claims in NewsweekWhat’s in a Name? Or, Will Vaccination Turn Your Children into Cows? on the History of Vaccines websiteDPT: Vaccine Roulette - 1982 NBC documentaryA Shot in the Dark by H. CoulterDravet Syndrome entry of VaxopediaCoronavirus: Operation Warp Speed US Dept. of Defense websiteVaccines: The Basics on the CDC websiteMaking Vaccines: How Are Vaccines Made? on the Children's Hospital of Philadelphia websiteHow Are Vaccines Made and Why Do They Work? on PKID websiteWhat Is the Difference Between Immunization and Vaccination? on Very Well HealthThe online anti-vaccine movement in the age of COVID-19 in The LancetThe MMR vaccine and autism: Sensation, refutation, retraction, and fraud in The Indian Journal of PsychiatryBook review in Nature for The Doctor Who Fooled the World by Brian DeerCallous Disregard: Autism and Vaccines--The Truth Behind a Tragedy, Andrew Wakefield's discredited bookNew Zealand Immunisation Advisory Centre Information for Parents about the film "Vaxxed: From Cover-up to catastropheWe watched the movie ‘Vaxxed’ so you don’t have to article on StatNews7 things about vaccines and autism that the movie ‘Vaxxed’ won’t tell you in The Washington PostTrailer for "The Pathological Optimist" 2017 documentaryThe Anti-vaccination Movement: A Regression in Modern Medicine in CureusAnti-Vaccine Celebrities Have Inordinate Amount of Influence on the Pharmacy TimesNew World Order episodes of Conspiracy Clearinghouse on YouTubeRobert F. Kennedy's Children's Health Defense websiteNatural herd immunity should not be used as a means of pandemic control on The BMJ Opinion websiteThe false promise of herd immunity for COVID-19 in NatureCOVID-19 anti-vaxxers use the same arguments from 135 years ago on The ConversationSeven ways to talk to anti-vaxxers (that might actually change their minds) on HealthyDebate.caBest practice guidance: How to respond to vocal vaccine deniers in public paper by the World Health OrganizationInside the Mind of an Anti-vaxxer in The AtlanticBook announcement for Anti-vaxxers - How to Challenge a Misinformed Movement by Johnathan M. BermanFollow us on social for extra goodies:FacebookTwitterYouTube (extra videos on the topic, Old Time Radio shows, music playlists and more)Other Podcasts by Derek DeWittDIGITAL SIGNAGE DONE RIGHT - Winner of 2020 Communicator Award of Excellence for Podcasts Series-Corporate Communications and on numerous top 10 podcast lists. PRAGUE TIMES - A city is more than just a location - it’s a kaleidoscope of history, places, people and trends. This podcast looks at Prague, in the center of Europe, from a number of perspectives, including what it is now, what is has been and where it’s going. It’s Prague THEN, Prague NOW, Prague LATER.

Shot in the Dark

The Morning Brief

Play Episode Listen Later Jan 5, 2021 23:39

Swift approval for Bharat Biotech's indigenous Covid-19 vaccine and Serum Institute of India's version of the Oxford-AstraZeneca vaccine has raised more doubts than enthusiasm. We talk to Dr. Amar Jesani, Editor of the Indian Journal of Medical Ethics, and ET's Divya Rajagopal to understand the concerns

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Vaccinating against COVID-19: Has the vaccine development been a fair and transparent process?

Play Episode Listen Later Dec 29, 2020 27:50

This is the second episode in the two-part series on developing COVID-19 vaccines for the Suno India show. In the first episode of the series, we discussed the different stages of clinical trials and how the vaccines were developed so fast. In the second part, we are addressing key concerns about the cynicism around vaccine development. What are the legal processes involved in clearing the vaccines for mass vaccination in India? Were the vaccine trials fair and ethical? Is all the relevant information related to the vaccine development shared with the public? For this episode, Menaka Rao spoke to Dr Amar Jesani, an expert bioethicist and teacher who has founded the prestigious journal, Indian Journal of Medical Ethics and advocate Murali Neelakantan, an expert in healthcare laws and drug development in India. Also listen “Vaccinating against COVID-19: How did we get so many vaccines so fast?" See sunoindia.in/privacy-policy for privacy information.

covid-19 transparent medical ethics vaccinating vaccine development indian journal suno india

Vaccinating against COVID-19: How did we get so many vaccines so fast?

covid-19 indian vaccines bioscience medical ethics vaccinating ashoka university indian journal

Play Episode Listen Later Dec 29, 2020 17:25

The Indian government is gearing up for mass COVID-19 vaccinations. The question foremost on everyone's minds are how were they developed so fast. The first episode of this two-part series for the Suno India Show gives a step-by-step explanation of vaccine development and what is different this time around. For this episode, we feature the expert voices of Dr Shaheed Jameel, currently the director of the Trivedi School of Biosciences at Ashoka University, and Dr Amar Jesani, an expert bioethicist and teacher who has founded the prestigious journal, Indian Journal of Medical Ethics. Also Listen “Vaccinating against COVID-19: Has the vaccine development been a fair and transparent process?“ See sunoindia.in/privacy-policy for privacy information.

(2/2) Role of medical professionals in criminal justice with Dr Amar Jesani. Part 2: Narco-analysis

Bioethics and Us

Play Episode Listen Later Dec 25, 2020 14:06

In this episode we speak with Dr. Amar Jesani an independent consultant, researcher and teacher in bioethics and public health. He is the co-founder of the Forum for Medical Ethics Society and the editor of the Indian Journal of Medical Ethics. This episode is part 2 of 2 episodes exploring the role of medical professionals in criminal justice. This episode specifically focuses on narco-analysis. Hope you enjoy! Please do contact me with any questions, concerns or ideas you may have. I'm always looking forward to having exciting conversations to learn and grow! Also, if you working in the bioethics field or any relating to it, I would love to connect with you and have you share your ideas and perspectives on future episodes. Please email me at bioethicsandus@gmail.com

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ZENPod Season 2, episode 9 with Kaushik Bhattacharya

Venkatesh Mahadevan

Play Episode Listen Later Dec 16, 2020 37:13

"ZENPod", Season-2, episode 9, featuring Dr. Kaushik Bhattacharya, a Doctor, Social Worker and Surgeon, who has helped our soldiers from Indian Army, the BSF, SSB, CRPF, ITBP and other paramilitary forces with his expertise. He has recently been awarded the title of “Icon of North Bengal” by the Governor. He has recently been conferred fellowship from the Royal College of Surgeons, Glasgow. He has been awarded the ‘Director General Border' Security Commendation Roll thrice, Additional Director General Medical Commendation, 4 times. “Spirituality is when I do good to others, and they bless me…”,– says Kaushik Bhattacharya in his talk with Venkatesh Mahadevan Kaushik did his MBBS from MGM Medical College, Jamshedpur in 1992 and MS in Surgery from SCB Medical College, Cuttack in 1997. He passed the Diplomate of National Board of Examination in Surgery in 2000. He was working as Assistant Professor in Surgery at Sri Ramachandra Medical College and Research Institute till 2003 when he was sent on deputation in Cooch Behar, a small heritage town in North Bengal. He settled down in Siliguri subsequently and is working as a Consultant in the various hospitals. He is also working as Specialist in Surgery for the Central Armed Police Forces Composite Hospital, Kadamtala on contractual basis since 2010. Dr. Bhattacharya is the Member, Editorial Board, Indian Journal of Surgery and Sectional Editor, Hepatopancreaticobiliary, Journal of Minimal Access Surgery. He has more than 70 publications in various International and national surgical journals. He has delivered the prestigious Dr Santok Singh Endowment Oration in the Association of Surgeons of India Conference at Bhubneshwar 2019. He has received fellowship from the Association of Surgeons of India, Fellow of American College of Surgeons. He is also the Member of National Academy of Medical Sciences. He has performed may critical surgery for the BSF SSB CRPF ITBP and other paramilitary forces and also help Indian Army in major surgeries during the time of crisis. and appreciation letter from the head of various forces on many occasions. He is associated with Rotary Club of Siliguri Uttorayon and takes part in various social activities of this region. He was given appreciation letter by the Member of West Bengal Legislative Assembly of Nagrakata constituency for giving surgical treatment to the tea garden employees at a free or concessional rate. “ZENPod” is a Podcast series that features trailblazers from different walks of life, with a purpose to build an empowered eco-system where learnings and experiences from these enlightened professionals, will be available within “arms reach of desire” for those who aspire to scale higher and wish to contribute, in their life's pursuit.

(1/2) Role of medical professionals in criminal justice with Dr Amar Jesani. Part 1: Torture

Bioethics and Us

Play Episode Listen Later Dec 9, 2020 27:20

In this episode we speak with Dr. Amar Jesani an independent consultant, researcher and teacher in bioethics and public health. He is co-founder of the Forum for Medical Ethics Society and editor of the forum's publication, the Indian Journal of Medical Ethics. Since 1979, he has completed 20 research and training projects in public health and bioethics; and has co-authored and co-edited eight books. This episode is part 1 of 2 episodes exploring the role of medical professionals in criminal justice. This episode specifically focuses on torture. Hope you enjoy! Please do contact me with any questions, concerns or ideas you may have. I'm always looking forward to having exciting conversations to learn and grow! Also, if you working in the bioethics field or any relating to it, I would love to connect with you and have you share your ideas and perspectives on future episodes. Please email me at bioethicsandus@gmail.com

criminals forum amar torture criminal justice medical professionals medical ethics indian journal

A new perspective on the ethics of ART with Ms Sandhya Srinivasan

Bioethics and Us

Play Episode Listen Later Nov 23, 2020 29:34

In this episode we speak with Ms Sandhya Srinivasan, a freelance journalist, member of the World Association of Medical Editors and researcher with a master's degrees in sociology and public health. She writes primarily on medical ethics and public health in academic journals as well as in the media. She is the consulting editor of the Indian Journal of Medical Ethics. Additionally In 2002-2003, she was an Ashoka Fellow for her work in medical ethics and has conducted research and written for several international bodies including UNICEF. This episode is focused on assisted reproductive technology, the infertility industry and its ethical implications. Hope you enjoy! Please do contact me with any questions, concerns or ideas you may have. I'm always looking forward to having exciting conversations to learn and grow! Also, if you working in the bioethics field or any relating to it, I would love to connect with you and have you share your ideas and perspectives on future episodes. Please email me at bioethicsandus@gmail.com

ethics unicef new perspectives medical ethics srinivasan sandhya world association ashoka fellow indian journal

11. Oscillatoria: Slimy Asexual POND Scum

Darwin's Deviations

Play Episode Listen Later Nov 17, 2020 33:01

The most asexual episode…that will blow you away with the most F-bombs! Oscillatoria, and all cyanobacteria, are slimy, scummy, invisible…they do not need to be handsome, they are their own partners, and they are EVERYWHERE! You cannot escape them, they will even tear themselves apart in order to hitch a ride on your muddy sneaker….follow you home..and terrorize you with their overt photosynthetic efficiency…and existence…and capabilities to survive for over 3.5 billion years without ever getting laid! However dreadful their lives may seem…they're more successful than our own :) ====================== Send us suggestions and comments to darwinsdeviations@gmail.com Intro/outro sampled from "Sequence (Mystery and Terror) 3" by Francisco Sánchez (@fanchisanchez) at pixabay.com Sound effects obtained from https://www.zapsplat.com Image Credit (Episode image is heavily edited, the image owner reserves all rights to their image, and is not affiliated with our podcast) SOURCES: Wikipedia: Prokaryote Wikipedia: Cyanobacteria Microbe Wiki: Oscillatoria Oscillatoria: Occurrence, Thallus Structure and Reproduction Oscillatoria – Classification , Occurrence , Structure and Reproduction AlgaeBase: Oscillatoria Vaucher ex Gomont, 1892 Nuernberg, Dennis & Mariscal, Vicente & Parker, Jamie & Mastroianni, Giulia & Flores, Enrique & Mullineaux, Conrad. (2014). Branching and intercellular communication in the Section V cyanobacterium Mastigocladus laminosus, a complex multicellular prokaryote. Molecular microbiology. 91. 10.1111/mmi.12506. Rani, V. & Ulagalanthaperumal, Elaya Perumal & Sonaimuthu, Palanivel. (2016). Morphology and taxonomy of Oscillatoria princeps Vaucher ex gomont (OSCILLATORIALES, OSCILLATORIACEAE). Indian Journal of Education and Information Management. 5. 1-5. Muhlsteinova, Radka & Hauer, Tomáš & Ley, Paul & Pietrasiak, Nicole. (2018). Seeking the true Oscillatoria: A quest for a reliable phylogenetic and taxonomic reference point. Preslia. 90. 10.23855/preslia.2018.151. Brahamsha, B. and D. Bhaya. “Motility in Unicellular and Filamentous Cyanobacteria.” (2013). Ridley, Christian & Faulkner, D & Haygood, Margo. (2005). Investigation of Oscillatoria spongeliae-Dominated Bacterial Communities in Four Dictyoceratid Sponges. Applied and environmental microbiology. 71. 7366-75. 10.1128/AEM.71.11.7366-7375.2005.

Dr Jonathan Campion - Director for Public Mental Health and Consultant Psychiatrist

Real World Public Mental Health

Play Episode Listen Later Oct 30, 2020 61:00

Welcome to episode one! This podcast is released in conjunction with PHE's webinar on 3rd November 2020: Prevention & Promotion for Better Mental Health in Local Systems (COVID-19). Click for details and to register for this free event.Stu King chats with Dr Jonathan Campion, Director for Public Mental Health & Consultant Psychiatrist at South London & Maudsley NHS Foundation Trust. Jonathan is visiting Professor of Population Mental Health at UCL & Fellow of Royal College of Psychiatrists. He is involved in development and implementation of local, national and international public mental health (PMH) strategy.Stu and Jonathan look at Jonathan's journey into PMH, including gathering evidence for determinants of mental disorder and wellbeing, and evidence for interventions. He has also worked in local implementation, writing guidance for needs assessments.Turning to current PMH, they look at impacts and costs of mental disorder and wellbeing (8:37). Plus, causes and risk factors which can increase them (11:34 ), such as COVID-19, through reduced social interactions and the infection itself (13:37).Jonathan shares examples of cost effectiveness and societal benefits of interventions, such as parental, school and workplace (21:39). However, there is an implementation gap (33:33). With a minority of those with mental disorder in UK receiving treatment, Jonathan shares causes of this gap (35.42) and actions that can narrow it (41:01).Links to articles & resources: Economic case for improved coverage of PMH interventions. The Lancet Psychiatry (2018)PMH: key challenges and opportunities. BJPsych International (2018)Launch of ‘PMH: Evidence, practice and commissioning. RSPH (2019)(Navigation available here)PMH and associated opportunities. Indian Journal of Psychiatry (2020)Addressing the PMH challenge of COVID-19. The Lancet Psychiatry (2020)WPA Working Group launches PMH Briefing on COVID-19. WPA(2020)The Need for a PMH Approach to COVID-19. WSP (2020)Public Mental Health e-learning session. HEE (2020)Thanks to BSPHN, PHE, ADPH, LGA, Centre for Mental Health, Mental Health Foundation & NIHR School for Public Health Research

Can Music Actually Enhance Your Workout?

That's Healthy, Right?

Play Episode Listen Later Oct 11, 2020 4:45

Does listening to music, something many of us do when we exercise, really do anything for your training performance?Because it’s such a popular motivator in sports and fitness, it would only make sense that it does something to help. Or, is it magical thinking that your favorite tunes make you stronger or faster?Get ready for some good news — and some bad — about how music may affect your workout.In this episode of That’s Healthy, Right?, we’ll dig into the research on whether or not music helps increase your maximum strength, how it may actually boost the number of reps you can do, help you push a little bit harder, run a little bit farther, and even recover faster.To ask a question, read the transcript, or learn more, visit bornfitness.com/thats-healthy-right.Don’t forget to Subscribe to the show, and Rate or Review wherever you tune in!Resources:The Psychophysiological Effects of Different Tempo Music on Endurance Versus High-Intensity Performances — Frontiers in PsychologyErgogenic and psychological effects of synchronous music during circuit-type exercise — Psychology of Sport and ExerciseThe effects of music tempo and loudness level on treadmill exercise — ErgonomicsCan Listening to Music Improve Your Workout? — National Center for Health Research Revisiting the exercise heart rate-music tempo preference relationship — Research Quarterly for Exercise and SportEffect of different musical tempo on post-exercise recovery in young adults — Indian Journal of Physiology and PharmacologyEffects of self-selected music on maximal bench press strength and strength endurance — Perceptual and Motor SkillsEffects of self-selected music on strength, explosiveness, and mood — Journal of Strength and Conditioning Research The effect of music during warm-up on consecutive anaerobic performance in elite adolescent volleyball players — International Journal of Sports MedicineMusic Mindset: Don’t Wait for Tomorrow — Born Fitness

music sports strength psychology healthy exercise journal workout enhance physiology international journal perceptual indian journal research quarterly

William's Podcast

Play Episode Listen Later Oct 9, 2020 20:22

To all intents and purposes although the word paper is the origin and historical development derived from papyrus, yet the two are produced very differently and the development of the first is distinct from the development of the second. Correspondingly, the fact that paper dates back almost 2,000 years to when inventors in China first crafted cloth sheets to record their drawings and writings. Moreover before then, global citizens communicated through pictures and symbols etched on stone, bones, cave walls, or clay tablets. And Paper as we know it today was first made in LeiYang, China by Ts'ai Lun, a Chinese court official. In all likelihood, Ts'ai mixed mulberry bark, hemp and rags with water, mashed it into pulp, pressed out the liquid, and hung the thin mat to dry in the sun."Paper technology : official journal of the Paper Industry Technical Association". WorldCat. Retrieved 10 January 2017. "papyrus". Dictionary.com Unabridged. Random House. Retrieved 20 November 2008. "Towards paperless information systems". CERN Document Server. Academic Press. 1978. Retrieved 2016-02-10. Habib, Irfan (2011). Economic History of Medieval India, 1200-1500. Pearson Education India. pp. 95–96. ISBN 9788131727911. https://www.jstor.org/journal/collegecouranthttps://www.jstor.org/stable/i40211191 W.C.Griffis https://www.synonyms.com/antonyms/understatement Murray, Stuart A. P. The Library: An illustrated History. Skyhorse Publishing, 2009, p. 57. SAK Ghori; A Rahman (1966). "Paper Technology in medieval India". Indian Journal of History of Science. 2: 135–136. Tsien 1985, p. 38 "PT V1 Nr1" (PDF). Paper Technology. Retrieved 13 July 2020. Archive". PITA. Retrieved 13 July 2020. Bloom, Jonathan (2001). Paper Before Print: The History and Impact of Paper in the Islamic World. New Haven: Yale University Press. pp. 8–10, 42–45. ISBN 0-300-08955-4. Burger, Peter (2007). Charles Fenerty and his paper invention. Toronto: Peter Burger. pp. 25–30. ISBN 978-0-9783318-1-8. OCLC 173248586. Archived from the original on 19 April 2009. Retrieved 19 May 2009. DeVinne, Theo. L. The Invention of Printing. New York: Francis Hart & Co., 1876. p. 134 Gittens, William Anderson, Author, Media Arts Specialist, Student of Film, License Cultural Practitioner Gittens,William Anderson,Author, Cinematographer,Dip., Com., Arts. B.A. Media Arts Specialists’ Editor-in-Chief Devgro Media Arts Services Publishing ®2015 License Cultural Practitioner, Publisher, CEO Devgro Media Arts Services®2015 http://www.digitaljournal.com/tech-and-science/technology/from-paper-to-the-press-two-technologies-that-changed-the-world/article/487825 http://www.scienceprojectideas.co.uk/testing-paper-for-strength.html https://education.jlab.org/qa/atomicstructure_11.html https://en.wikipedia.org/wiki/Environmental_impact_of_paper https://en.wikipedia.org/wiki/History_of_paper https://en.wikipedia.org/wiki/History_of_paper#CITEREFBarrett2008 https://en.wikipedia.org/wiki/History_of_paper#CITEREFTsien1985 https://en.wikipedia.org/wiki/History_of_paper#CITEREFWilkinson2012 https://en.wikipedia.org/wiki/History_of_paper#Shift_from_parchment_to_paper https://en.wikipedia.org/wiki/Industrial_Revolution#Paper_machine https://en.wikipedia.org/wiki/Main_Page https://en.wikipedia.org/wiki/Paper https://en.wikipedia.org/wiki/Paper#CITEREFBurns1996 https://en.wikipedia.org/wiki/Paper#CITEREFTsien1985 https://en.wikipedia.org/wiki/Paper#HistorSupport the show (http://www.buzzsprout.com/429292)

Podcast #25: Jacquis Neal on White Supremacy, Trump Presidency and US Election 2020 | Sollu Kaburz

Sollu Kaburz

Play Episode Listen Later Oct 6, 2020 69:14

Host: Najeeb Guest: Jacquis Neal Language: English Jacquis Neal is an actor, comedian and podcast host living in Los Angeles by way of Chicago, IL. Jacquis is the co-host of the Earwolf Podcast, Culture Kings. He is a house team performer and producer at the UCB LA Theatre, performing improv and sketch comedy on Harold and Maude Night respectively. On the screen, Jacquis has appeared on TV shows Liza OnDemand, Bless This Mess, Kingpin Katie, was the American voice of Fuba on the Netflix series Brotherhood, and Silvio on Netflix series Omniscient. He's been in a few national commercial spots, and well as many comedy shorts on the web. Jacquis was born and raised in Chicago, IL, where he was an active member of Chicago's amazing theatre scene performing at venues like Lifeline Theatre and American Theatre Company and many more. He is proud to be from a place with the best food and vibe alive, the 2016 World Series Champion Cubs, and where he grew up with a front row seat watching Michael Jordan play. Enough said. Alok Prasanna Kumar is a Political analysis enthusiast and a Legal Expert. He is Currently a Senior Resident Fellow at Vidhi Karnataka and an advocate. Formerly a lawyer in Delhi with experience in taxation laws, constitutional law, administrative law and arbitration. Constant courts critic and author of the Contumacious Curmudgeon newsletter. He writes a monthly column for the Economic and Political Weekly and has published in the Indian Journal of Constitutional Law and National Law School of India Review apart from media outlets such as The Hindu, Indian Express, Scroll, Quint and Caravan. He has practiced in the Supreme Court and Delhi High Court from the chambers of Mr Mohan Parasaran, and currently also co-hosts the Ganatantra podcast on IVM Podcasts. Find Jaquis Neal's online profile here: http://www.jacquisneal.com/ Listen to Sollu Kaburz podcast on Spotify here: https://open.spotify.com/show/5ETKqWz... Follow Sollu Kaburz Podcast on Social Media for updates: Instagram: https://www.instagram.com/sollukaburz/Facebook: https://www.facebook.com/SolluKaburz/

Podcast #24: Bihar Elections - 2020 with Ganatantra Podcast host Alok Prasanna Kumar | Sollu Kaburz

Sollu Kaburz

Play Episode Listen Later Sep 28, 2020 49:56

Host: Najeeb Guest: Alok Prasanna Kumar Language: English Alok Prasanna Kumar is a Political analysis enthusiast and a Legal Expert. He is Currently a Senior Resident Fellow at Vidhi Karnataka and an advocate. Formerly a lawyer in Delhi with experience in taxation laws, constitutional law, administrative law and arbitration. Constant courts critic and author of the Contumacious Curmudgeon newsletter. He writes a monthly column for the Economic and Political Weekly and has published in the Indian Journal of Constitutional Law and National Law School of India Review apart from media outlets such as The Hindu, Indian Express, Scroll, Quint and Caravan. He has practiced in the Supreme Court and Delhi High Court from the chambers of Mr Mohan Parasaran, and currently also co-hosts the Ganatantra podcast on IVM Podcasts. Find Alok Prasann Kumar's online profile here: https://vidhilegalpolicy.in/team/alok... Find Gantantra Podcasts link here: https://www.youtube.com/c/IVMPodcasts... Listen to Sollu Kaburz podcast on Spotify here: https://open.spotify.com/show/5ETKqWz... Follow Sollu Kaburz Podcast on Social Media for updates: Instagram: https://www.instagram.com/sollukaburz/Facebook: https://www.facebook.com/SolluKaburz/

“Sick” Days & Diabetes: Primary Prevention and Management

The Huddle: Conversations with the Diabetes Care Team

Play Episode Listen Later Jul 29, 2020 16:29

Resources:ADCES resources for sick day management: DiabetesEducator.org/SickDay.This episode was provided by Ascensia Diabetes Care, Makers of the CONTOUR®NEXT Brand of Blood Glucose Meters and Test Strips.  To learn more about the accuracy of CONTOUR®NEXT Brand Meters and receive sample for your clients, visit CONTOURNEXTPRO.com.References:Butler, S.O., Btaiche, I.F. & Alaniz, C. (2005) Relationship between hyperglycemia and infection in critically ill patients. Pharmacotherapy. 25(7), 963-76. https://doi.org/10.1592/phco.2005.25.7.963 Carey,l. et al. (2018) Risk of Infection in Type 1 and Type 2 Diabetes Compared With the General Population: A Matched Cohort Study. Diabetes Care 2018 41(3): 513-521.Kim, E.J et. al. (2019) Diabetes and the Risk of Infection A National Cohort Study. Diabetes and Metabolism Journal, 804-814. DOI: https://10.4093/dmj.2019.0071Peleg A, et al. (2007). Common Infections in Diabetes: Pathogenesis, Management and Relationship to Glycaemic Control. Diabetes/Metabolism Research and Review 2007;(23) 3–13Casqueiro, J. et al. Infections in patients with diabetes mellitus: A review of pathogenesis. Indian Journal of Endocrinology and Metabolism 2012 (16 Suppl. 1):S27–S36Ketoacidosis (DKA). American Diabetes Association. http://www.diabetes.org/living-with-diabetes/complications/ketoacidosis-dka.html. Accessed May 20, 2020. Brutsaert, E (2019). Diabetic ketoacidosis (DKA). Merck Manual Professional Version. http://www.merckmanuals.com/professional/endocrine-and-metabolic-disorders/diabetes-mellitus-and-disorders-of-carbohydrate-metabolism/diabetic-ketoacidosis-dka. Accessed May 20, 2020.Tonyushkina, K. et al. (2009) Glucose Meters: A Review of Technical Challenges to Obtaining Accurate Results. Journal of Diabetes Science and Technology. 3(4): 971–980. Maahs, D.M. et al. (2015) Effect of Acetaminophen on CGM Glucose in an Outpatient Setting. Diabetes Care 2015 (38) e158-e159. https://doi.org/10.2337/dc15-1096Centers for Disease Control and Prevention. (2020, March). Managing Sick Days. Retrieved from www.cdc.gov/diabetes/managing/flu-sick-days.html.Noti J. D. et al. (2013). High Humidity Leads to Loss of Infectious Influenza Virus from Simulated Coughs, PLoS ONE 8(2): e57485. https://doi.org/10.1371/journal.pone.0057485, American Diabetes Association (2020, Jan). Introduction: Standards of Medical Care in Diabetes—2020 Diabetes Care 2020 Jan; 43(Supplement 1): S1-S2. https://doi.org/10.2337/dc20-Sint Retrieved from (https://care.diabetesjournals.org/content/43/Supplement_1)

Who will you save with the limited resources you have during the Pandemic?

Play Episode Listen Later Jul 24, 2020 45:45

Patients with severe covid-19 disease need hospital care, intensive care. Some of them will need to be put on a ventilator. According to an April 2020 report of the Centre for Disease Dynamics Economics and Policy, there are an estimated 19 lakh hospital beds in India, 95,000 ICU beds and 48,000 ventilators. Most of these are concentrated in the metros of seven states. These were not enough before covid-19. Public hospitals have always been overburdened. Now with the pandemic, they are overwhelmed. There are distressing accounts of exhausted healthcare providers trying to cope with the flood of patients with this disease. Without protective equipment and safety protocols, they are getting infected in large numbers. And health professionals faced with crowds of sick people and limited resources may be forced to decide who to treat first, and when to withdraw treatment. This dilemma is faced by healthcare providers across South Asia. In April this year, the Centre for Biomedical Ethics and Culture (CBEC) in the Sind Institute of Urology and Transplantation in Karachi, Pakistan published guidelines for ethical healthcare decision-making in the COVID-19 pandemic in Pakistan. CBEC is the first and the only centre for biomedical ethics in Pakistan In this episode, Sandhya Srinivasan, consulting editor of the Indian Journal of Medical Ethics spoke to Dr Farhat Moazam is the founder and chairperson of CBEC about how one decides the allocation of critical medical equipment with the rising number of COVID-19 cases and about the guidelines published by CBEC. See sunoindia.in/privacy-policy for privacy information.

covid-19 pandemic public patients policy pakistan icu south asia karachi urology transplantation medical ethics limited resources biomedical ethics indian journal cbec

Why are most of the medicines being approved for COVID-19 so expensive?

covid-19 families expensive approved rs medicines cancer patients medical ethics indian journal

Play Episode Listen Later Jul 23, 2020 29:45

There is an urgent need to find a cure for COVID-19. Old drugs that have been developed and approved for one disease are now being evaluated to see if they can be used to reduce the severity and to bring down mortality of this new disease. Some drugs have been proven to be effective. Some have been found to have limited impact. Yet others have not been proven effective but are widely used anyway. All but one of these drugs is priced in the tens of thousands of rupees per course of treatment out of reach of most patients of COVID-19. Add the charges for other drugs and for the hospital. Families of patients are looking at bills of lakhs and lakhs of rupees. The bulk of people falling ill with COVID-19 are the poor and most vulnerable to infection because of their cramped living conditions, or because their work requires interaction with the public, such as frontline healthcare workers, bus conductors, shopkeepers, street vendors. But their doctors have told them that these drugs work. So they are among those standing in long lines outside pharmacies, for medicines which cost Rs 30,000 upwards. In this episode, Sandhya Srinivasan, consulting editor of the Indian Journal of Medical Ethics talks to Advocate Veena Johari who has worked for decades on legal action and has recently written a letter on behalf of the Cancer Patients' Aid Association to revoke a patent on Remdesivir. See sunoindia.in/privacy-policy for privacy information.

Are controlled human infection studies for a COVID 19 vaccine ethical? A bioethicist explains why not.

covid-19 vaccines studies ethical infection controlled medical research medical ethics indian council bioethicist indian journal

Play Episode Listen Later Jul 22, 2020 39:30

It's been over four months since the WHO declared COVID-19 to be a pandemic; millions of people worldwide have been infected, and more than half a million have died of this disease. While today the best response may be to track, test, track, isolate and treat, many public health communities believe that the virus is not going to go away without a vaccine. But it will take years to develop a vaccine moving from the lab to testing them for safety and efficacy, getting regulatory approval manufacturing at scale and finally reaching it to all the people who need it. Despite what the Indian Council of Medical Research has indicated, and then later denied, vaccines don't go from the lab to the shot in your arm in six weeks. The process of research into vaccine development also raises some very important ethical issues. What are the ethical challenges involved in the research and development of vaccines? For this episode, Sandhya Srinivasan, consulting editor of the Indian Journal of Medical Ethics asks Dr Amar Jesani, a senior bioethicist and editor of the Indian Journal of Medical Ethics very pertinent questions regarding the ethical challenges of using controlled human infection studies for a COVID 19 vaccine. See sunoindia.in/privacy-policy for privacy information.

The need for evidence-based medicine in treating COVID-19