Podcasts about PAH

Seth Hall, MBA, RRT, takes listeners on a journey through the past, present, and future of inhaled therapies. Discover how these treatments have evolved, the life-changing benefits they offer, and the revolutionary technologies that could redefine outcomes for PAH and PH-ILD patients. This Special Edition episode is sponsored by Liquidia. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com. #phawareMD #PHILD @Liquidia_Corp #PRINTTechnology 

TEX-TREK Mission 329: STAR TREK: DS9's "The Assignment" Back-Trekking RetrospectiveThis week we are diving back into the shadows of DS9 for a Keiko-centric thriller! The season 5 episode, "The Assignment," doesn't get talked about much, but it has a lot to offer. Join us as we discuss the eerie dynamics of Rosalind Chao playing her own hostage, the ominous reveal of the Pah-wraiths, O'Brien's psychological tension, and Rom once again showing how great of a guy he can be. Stan from Salon Trek joins Taylor and Fatheree as the guest this week.As always, available in both video and audio-only formats.Watch on YouTube:https://www.youtube.com/watch?v=W09pxPbA7WgGet RSS feed:https://anchor.fm/s/f37edb0c/podcast/rssApple Podcasts:https://podcasts.apple.com/us/podcast/tex-trek/id1495605753?uo=4Spotify:https://open.spotify.com/show/6mdZ030Klldxwn7SSc5PKp?si=3BOqsbQER9Ssfppqk7lofQ&fbclid=IwAR1M1uH_xBE1lYWcwQocoDzjoVSsLmCgBt08TCEYAltwIH3MPC0S60bMCsEJoin our Discord server:https://discord.gg/YXPeRyQh7ySupport us on Patreon:https://www.patreon.com/txtrekStar Trek: Deep Space Nine, Season 5 Episode 5"The Assignment"Teleplay by Bradley Thompson & David WeddleStory by Robert Lederman & David R. LongDirected by Allan KroekerAfter returning from the Fire Caves on Bajor, Keiko's body is controlled by an alien lifeform that forces her husband O'Brien to do its bidding or else face the death of his wife.http://www.facebook.com/textrekhttps://www.instagram.com/txtrek/http://twitter.com/TxTrekhttps://www.tiktok.com/@txtrekEmail: fathereeactual@tex-trek.com

Wed, 30 Apr 2025 19:02:04 +0000 https://feed.neuezwanziger.de/link/21941/17019398/wolfram-weimer-trumps-niedergang-papst-prozession-eu-aussenpolitik-neue-zeitrechnungnung-und-sportideologie 75eba8b68f9807ef113d2a80dea51e4e Wolfgang und Stefan besprechen den April 2025 Welche Qualifikation braucht ein Kulturstaatsminister? Pah, das ist ja nicht mal ein richtiger Minister. Also eigentlich keine. Vielleicht wäre etwas mit Medien schön in der Biographie. Will uns die neue Bundesregierung ärgern? Ist Kultur von dort aus gesehen wirklich nur noch ein linksgrünversifftes Projekt, das ein paar hinter die Löffel bekommen soll? Oder ist die Ernennung von Wolfram Weimer einfach Sinnbild für die neue Herangehensweise, für die Modernisierung des Staates auf Verkaufsflächendesigner zu setzen, als Wirtschaftsministerin eine Unternehmensmanagerin zu wählen und überall Juristen zu platzieren, außer im Innenministerium? Wir gehen dem Denken von Wolfram Weimer heute im Detail nach, Wolfgang hat sein Buch gelesen. Danach begutachten wir die Signatur-Politik von Donald Trump. Einfach "Zölle" zu sagen, greift viel zu kurz. Hier klammern Leute am Staat, die ihn zerstören, was sie sich nicht eingestehen können, weil dann die anderen gewonnen hätten. Im Wirtschaftskrieg Amerika gegen China sind es nun die Amerikaner, die den Gesichtsverlust fürchten. Anschließend sehen wir einsame Sportler im Wald, die mal keinen Blödsinn erzählen. KÄS-Termine 2025: Fr. 20.06. / Fr. 19.09. / Fr. 19.12. per Mail: neuezwanziger@diekaes.de SOMMERSALON am 23. August! Tickets gibts hier 00:00:57 Wolfgangs Smartphone Wolfgang erzählt, wie er durch den Kauf eines neuen Autos dazu gezwungen wurde, sich ein Smartphone anzuschaffen. Sein altes Nokia reichte nicht mehr aus, um die modernen Funktionen des Autos zu nutzen. Er beschreibt den Kauf eines iPhones als Verlust seiner Autonomie und Freiheit, da er sich nun der Technologie unterwerfen muss. Stefan versucht, ihm die praktischen Seiten des Smartphones näherzubringen, wie die Navigationsfunktion, die nicht nur im Raum, sondern auch in der Zeit navigiert, indem sie die Ankunftszeit vorhersagt. Wolfgang will das Smartphone jedoch nur für das Nötigste nutzen und nicht für soziale Medien oder ständige Erreichbarkeit. 00:09:06 Strafen für Apple und Meta Passend zu Wolfgangs neuem iPhone wird über eine EU-Strafe gegen Apple berichtet. Die EU-Kommission wirft Apple vor, im App Store andere Anbieter benachteiligt zu haben, indem es Hinweise auf günstigere Angebote außerhalb des Stores verhinderte. Apple soll 500 Millionen Euro Strafe zahlen. Stefan hält die Strafe für längst überfällig, aber angesichts des Lock-in-Effekts, den Apple über Jahre ausgenutzt hat, für zu gering. Wolfgang rechnet vor, dass die Strafe nur einen Bruchteil (0,15%) des möglichen Strafmaßes von bis zu 10% des globalen Jahresumsatzes ausmacht. Auch Meta (Facebook, Instagram) erhielt eine Strafe von 200 Millionen Euro wegen der Praxis, Nutzer vor die Wahl zwischen personalisierter Werbung oder einem Bezahl-Abo zu stellen. Beide Strafen werden als symbolisch und wenig abschreckend kritisiert. Es wird diskutiert, dass die EU sich zwar nicht scheut, US-Tech-Konzerne zu bestrafen, aber die Abhängigkeit von deren digitaler Infrastruktur (Google Suche, Cloud-Dienste etc.) eine härtere Gangart verhindert. Matt Binder von Mashable erklärt, warum Meta die Strafe als "Tariff" (Zoll) bezeichnet, um negative Assoziationen in den USA zu wecken. 00:22:19 Papst beerdigt Stefan berichtet von seinem Wien-Besuch und der dortigen Schatzkammer, wo die Verschmelzung von staatlicher und sakraler Macht sichtbar wird. Im Kontrast dazu steht die als eher schlicht empfundene Beerdigungszeremonie für Papst Franziskus im Petersdom. Ein besonderer Moment war jedoch der Trauerzug mit dem Leichnam des Papstes durch das historische Zentrum Roms zur Basilika Santa Maria Maggiore, wo er beigesetzt wurde. Dieser Akt wurde selbst von nicht-religiösen Menschen als Gänsehautmoment empfunden und als letzter weltlicher Einschlag des Papstes gewertet. Wolfgang erinnert an die Tradition in Wien, verstorbene Burgschauspieler im Sarg um das Burgtheater zu tragen. Es wird auch die politische Dimension des Papsttums angesprochen, etwa die Rolle von Johannes Paul II. im Kalten Krieg oder Franziskus' Appelle gegen Aufrüstung. 00:28:15 Was denkt Wolfram Weimer Wolfram Weimer, ehemaliger Chefredakteur der Welt und Verleger (u.a. Cicero), wurde zum neuen Kulturstaatsminister ernannt. Die Entscheidung von Friedrich Merz löste viel Kritik aus, auch aus konservativen Kreisen. Jürgen Kaube (FAZ) bezweifelt Weimers Interesse an Kunst oder Geist. Die enge Verbindung zwischen Merz und Weimer (Golfpartner, Ludwig-Erhard-Gipfel, gegenseitige Lobpreisungen) wird beleuchtet. Wolfgang hat Weimers "Konservatives Manifest" gelesen, um dessen Denken zu verstehen. In einem Lanz-Auftritt von 2018 erklärt Weimer, Konservatismus sei wieder modern und bedeute nicht das Hängen am Gestern, sondern das Leben aus Werten, die immer gelten (Treue, Anständigkeit, Ehrlichkeit). Wolfgang kritisiert die Beliebigkeit dieser Definition. Stefan sieht Weimer als Gallionsfigur eines verlotternden Untergangs, der Chaos als Normalität verkauft. Weimers Buch wird analysiert: Er beklagt den Niedergang linker Weltanschauungen, interpretiert Böckenförde und Max Weber eigenwillig, fordert eine minimale Gesellschaft, kritisiert die "Bemutterung" durch den Staat (z.B. Verkehrsüberwachung) und sieht die Steuererklärung als "Marsch ins Freiheitsdefizit". Diese libertären Züge werden kritisiert. Weimer beklagt eine "Kleinkariertheit" durch Compliance-Regeln, die Geschenke und Geschäftsessen erschweren. Wolfgang hält das für Jammern auf hohem Niveau. Weimer stellt das Individuum über die Gesellschaft, fordert aber gleichzeitig Patriotismus und unterscheidet zwischen staatsbürgerlichem und natürlichem (Abstammungs-) Vaterland. Diese Widersprüche und die Nähe zum Ethnopluralismus werden diskutiert. Weimer bezieht sich positiv auf Oswald Spengler und beklagt die "biologische Selbstaufgabe" Europas durch niedrige Geburtenraten, spricht vom "eigenen Blut". Er kritisiert die Fokussierung auf die "dunkle Seite" des Kolonialismus in Lehrplänen. Die "Tugendrepublik" der "Gutmenschen" mit ihren Verboten (Fleisch, Kaminfeuer) und Quoten wird angeprangert. Am Ende plädiert er für eine Rechristianisierung Europas durch die Kultur. Abschließend äußern sich Michael Bröker und Micky Beisenherz zur Personalie. 02:20:54 Salon-Anmerkungen Es wird auf den kostenpflichtigen "Salon"-Teil des Podcasts hingewiesen, der die Sendung finanziert. Hörer werden gebeten, den Podcast zu teilen und zu bewerten, um die Sichtbarkeit zu erhöhen. Im nächsten Salon werden die Bücher "Abundance: How We Build a Better Future" von Esra Klein & Derek Thompson und "Die Welt nach dem Kapital" von Albert Wenger besprochen. Es wird erklärt, wie man den Salon über Steady, Patreon oder Apple Podcasts abonnieren kann. Man kann den Salon auch verschenken. Wolfgang kündigt Live-Termine in Zürich und Stuttgart an. Stefan erwähnt einen Termin in Mainz. Leseempfehlungen für den nächsten Salon werden gegeben. 02:26:38 Trumps Fanboys reden über Trumps Zölle Das Hauptthema ist Donald Trumps Zollpolitik. Es wird betont, dass dies seine "Signature Policy" ist, über die er seit Jahrzehnten spricht. Die aktuelle Situation mit Handelskriegen und Marktverwerfungen wird als direkte Folge dieser Politik gesehen. David McWilliams beschreibt Trumps Zoll-Formel als amateurhaft und inkompetent, basierend auf einer Formel, die ökonomisch keinen Sinn ergibt. Wolfgang erläutert den Unterschied zwischen früherer politischer Inkompetenz, die von Institutionen abgefangen wurde, und der heutigen Situation, in der Inkompetenz direkt an den Schalthebeln sitzt und zu chaotischer Politik führt. Stefan ergänzt, dass die Politik normalerweise durch die Verwaltung abgeschottet ist, dieser Mechanismus aber unter Trump zusammenbricht. Trumps Fokus auf Zölle ignoriert die Stärke Amerikas im Bereich digitaler Dienstleistungen und das Dollar-Privileg. Die Reaktion der Kapitalmärkte (steigende Zinsen für US-Staatsanleihen) wird als einziger wirksamer "Check" gegen Trumps Politik diskutiert, da sie die Staatsverschuldung und Kredite verteuert. Trump-Anhänger im "All In"-Podcast versuchen, die Politik zu rechtfertigen, räumen aber ein, dass das versprochene Wirtschaftswachstum ausbleibt. Hoss und Hopf sehen Trumps Handeln als Beschleunigung einer unvermeidbaren Rezession, damit er am Ende seiner Amtszeit als Gewinner dasteht – eine Logik, die als absurd kritisiert wird. Die Notwendigkeit, die heimische Landwirtschaft (Sojabauern) mit Milliardensummen zu subventionieren, um Wählerstimmen zu sichern, wird erwähnt. China reagiert mit der Drohung, westliche IP-Rechte zu ignorieren und Produkte selbst billiger anzubieten. Der Personalmangel in wichtigen Sektoren (Energieversorgung, U-Boot-Bau) in den USA wird thematisiert. Ben Shapiro plädiert für "Rugged Individualism" und lehnt staatliche Eingriffe ab, obwohl der Staat gleichzeitig Grenzen schützen soll. 04:10:24 Krieg: Gaza, Ukraine Die Berichterstattung über den Gaza-Krieg wird kritisiert. Es sei schwierig, seriöse Bilder und Informationen zu erhalten, ohne auf antisemitische Kanäle zu stoßen, die das Leid in Gaza zwar zeigen, aber gleichzeitig Hetze verbreiten. Seriöse Medien würden sich scheuen, die dramatische Lage abzubilden, was wiederum Antisemiten Vorschub leiste. Die Tagesthemen berichten über einen israelischen Angriff auf ein Krankenhaus, bei dem eine Hamas-Kommandozentrale getroffen worden sei, wobei jedoch medizinisches Gerät zerstört wurde. Diese Darstellung wird mit der Berichterstattung über den Ukraine-Krieg verglichen, wo eine solche Übernahme der russischen Darstellung undenkbar wäre. Ein Bericht über die Tötung von palästinensischen Sanitätern durch die israelische Armee, deren Leichen verscharrt wurden, wird erwähnt. Israel weist die Vorwürfe zurück und behauptet ohne Belege, es seien Hamas-Mitglieder gewesen. Ein israelischer Reserve-Offizier äußert sich besorgt über den zunehmenden Einfluss rechtsextremer Minister auf die Armee. Es wird die Entkopplung von Soldaten vom zivilen Leben und der Politik im Krieg thematisiert, illustriert durch Aussagen eines ukrainischen Soldaten, der nur noch seinen Frontabschnitt und seine Leute sieht. Die psychischen Folgen und die Verrohung durch den Krieg werden angesprochen. 04:28:46 EU und Aserbaidschan Die EU-Außenbeauftragte Kaya Kallas besucht Aserbaidschan. Stefan merkt an, dass Kallas im Westen kaum bekannt ist, in Russland aber neben Trump als Hauptgegnerin wahrgenommen wird. Kallas bezeichnet China als Schlüssel für den russischen Krieg, da es Russland wirtschaftlich und mit Dual-Use-Gütern unterstütze. Ihr Besuch in Baku wird kritisiert, da Aserbaidschan unter Präsident Aliyev einen Angriffskrieg gegen Armenier in Bergkarabach geführt hat, die Zivilgesellschaft unterdrückt und politische Gefangene hält. Dustin Hoffmann wirft der EU-Kommission vor, Werte zu ignorieren und sich brutalen Diktatoren anzubieten. Kallas lobt Aserbaidschan hingegen als wichtigen und verlässlichen Energiepartner, der der EU geholfen habe, sich von russischer Energie zu lösen. Es wird enthüllt, dass Aserbaidschan russisches Gas an die EU weiterleitet und somit von den Sanktionen profitiert. Kallas spricht dennoch von gemeinsamen Werten wie Menschenrechten und Rechtsstaatlichkeit und begrüßt eine Einigung im Friedensprozess mit Armenien. Der aserbaidschanische Außenminister Bayramov betont die guten Beziehungen zur Türkei und kritisiert die Biden-Administration als zu pro-armenisch. Er zeigt sich hoffnungsvoll bezüglich der neuen Trump-Administration. Aserbaidschan pflegt trotz seiner muslimischen Prägung enge Beziehungen zu Israel, bezieht Waffen und liefert Erdöl. Das Verhältnis zu Russland wird als "normal" beschrieben, wobei man die territoriale Integrität der Ukraine respektiere. Aserbaidschan wird als Beispiel für neue globale Akteure gesehen, die pragmatisch mit allen Seiten kooperieren und Einmischung ablehnen. 04:48:15 Neue Zeitrechnung Der Erfolgscoach Ed Mylett präsentiert ein Konzept zur Zeitmanipulation: Er teilt seinen Tag in drei 6-Stunden-Abschnitte (6-12 Uhr, 12-18 Uhr, 18-24 Uhr) und gewinnt so angeblich 21 Tage pro Woche. Wolfgang entlarvt dies als simple Einführung von Doppelschichten. Stefan meint, dass KI solche individuellen Zeitrechnungen problemlos in Standardzeit übersetzen könnte. 04:51:08 Neue Sportideologie Es wird eine aufkeimende Gegenbewegung zur rechten Vereinnahmung von Fitness und Männlichkeit beobachtet. Als Beispiel dient ein Fitness-Influencer, der in einem Video klarstellt, dass das Heben von Gewichten einen nicht zum "Warrior" oder Beschützer macht. Er kritisiert "Douchbags wie Andrew Tate", die Männern einreden, Frauen und Immigranten seien ihre Probleme. Er analysiert, wie rechte Ideologien über harmlos erscheinende Aktivitäten wie Fitness normalisiert und Fitness selbst radikalisiert wird. Der wahre Feind seien nicht andere Gruppen, sondern die Superreichen und CEOs, die von der Ungleichheit profitieren ("The enemy is up"). Er ruft Männer dazu auf, sich als Arbeiterklasse zu erkennen und sich nicht länger von den Eliten spalten zu lassen, um echten Wandel zu ermöglichen. Wolfgang hofft, dass solche Stimmen lauter werden. Stefan erwartet einen großen Backlash gegen die aktuelle politische Situation, die von Partikularinteressen und offensichtlicher Dummheit geprägt sei. Die Rolle von superreichen Geldgebern und Netzwerken innerhalb der CDU wird angesprochen. Komm' in den Salon. Es gibt ihn via Webplayer & RSS-Feed (zum Hören im Podcatcher deiner Wahl, auch bei Apple Podcasts und Spotify). Wenn du Salon-Stürmer bist, lade weitere Hörer von der Gästeliste ein. full Wolfgang und Stefan besprechen den April 2025 no Stefan Schulz & Wolfgang M. Schmitt 18258

 Zapraszamy na środowe wydanie "Onet Rano.", które poprowadzi Odeta Moro. Jej gośćmi będą: Aleksandra Leo, Polska 2050; Maciej Bagiński, prezes PAH; Leon Krześniak, wokalista; Monika Masalska i Szymon Masalski, autorzy książki "Nad wodę. Mikrowyprawy z Warszawy". Z kolei w części "Onet Rano. #WIEM" gościem Dominiki Długosz będzie Edward Augustyn, szef działu religijnego „Tygodnika Powszechnego”.

Easing the way in the ER for kids (and grownups)A visit to the hospital's emergency department can be stressful for anyone, but for children it's downright terrifying. All the strange sounds, smells and equipment in this unfamiliar place only heighten the fear an ill or injured child is already experiencing.But an ER doctor at Peace Arch Hospital in White Rock, British Columbia, is determined to change all that. Using an innovative combination of high-tech and what might be called “no-tech,” he is shifting his youngest patients' focus from needles and sutures to absorbing virtual reality roller coaster rides, helpful little robots—and a puppet named “Magrau.” In this episode of Power to Heal, you'll also learn how Dr. Amir Behboudi's determination to improve the ER patient experience isn't limited to children: he's been the driving force behind an inexpensive treatment that is offered in PAH's emergency room to reduce feelings of nausea in adult patients waiting for treatment.Dr. Behboudi's story begins with a trip to a neighbouring emergency room with his own son. What he experienced there inspired a technique that, with support from the Peace Arch Hospital Foundation, is capturing the attention of local media—and other hospitals in the area. Guests:Dr. Amir Behboudi, Emergency Room physician at Peace Arch Hospital.Stephanie Beck, CEO Peace Arch Hospital FoundationPower to Heal is hosted by Lance Peverley, a former newspaper reporter, editor of the Peace Arch News for 12 years, and a longtime resident of the White Rock/South Surrey area. About the Power to Heal podcast:Presented by Peace Arch Hospital Foundation in White Rock, British Columbia, Power to Heal takes you behind the scenes of an innovative hospital Foundation and introduces you to the team who find new and sometimes surprising ways to engage with the local community and help fund the best healthcare possible in the region. Since 1988, the Foundation has raised over $250 million for capital projects, medical equipment, and community health programs. Its passionate and caring team's number one priority is the prudent stewardship of your gifts and the resulting positive impact on patients and medical staff at Peace Arch Hospital and the entire White Rock-South Surrey community.Download Power to Heal wherever you get your favourite podcasts.Links:Peace Arch News: Making the ER less scary for kidsGlobal News: “New anti-nausea treatment”Support this and many other innovative programs and initiatives at Peace Arch Hospital. Visit www.pahfoundation.ca/ways-to-give/ to learn more.

Dr. Ron Zolty delves into groundbreaking advancements in treating pulmonary arterial hypertension. From the historical use of vasodilators to the revolutionary promise of sotatercept and seralutinib, Dr. Zolty unpacks how science is moving closer to halting—and possibly even reversing—PAH. This Special Edition episode is sponsored by Gossamer Bio. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com. #phawareMD @UNMCCOM @NebraskaMed @GossamerBio #clinicaltrial #PROSERA 

Returning for a second study this month, the JHLT Digital Media Editors invite first author Charlotte Van Edom to discuss the paper, “Apixaban plasma levels in patients with HeartMate 3 support.” As a cardiologist in training and a PhD candidate at the University Hospitals Leuven in Belgium, Van Edom's work focuses on hemocompatibility and mechanical circulatory support, covering both short-term and long-term support. The episode explores: The evolution of the use and understanding of direct oral anticoagulants (DOACs) during LVAD support, including the increased focus on Factor Xa inhibitors Encouraging findings from the study and what clinical practices might need to change if introducing apixaban Additional studies exploring DOACs in LVAD patients For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt. Treat or research pulmonary vascular diseases? Check out the first April episode for a study on sotatercept in PAH patients. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

Latest Developments in the Treatment of Pulmonary Arterial Hypertension    Guest: Robert P. Frantz, M.D. Host: Kyle Klarich, M.D.   Pulmonary arterial hypertension (PAH) is a serious disease manifested by vasoconstriction and obliteration of the pulmonary arterial vasculature resulting in rise in pulmonary artery pressure and resistance and culminating in right heart failure. Listeners will learn more about traditional treatments for PAH, as well as new anti-proliferative therapies in active clinical investigation, and what that means for the future of treatment.   Topics Discussed: What is most new and exciting in the treatment of pulmonary arterial hypertension? What monitoring is necessary in order to safely use sotatercept? What future developments do you envision for the field of pulmonary hypertension?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode. Podcast episode transcript found here.

Eric Austin, MD, MSCI discusses early detection among people who are at risk of pulmonary arterial hypertension (PAH), particularly those who would have genetic susceptibility, or who may have congenital heart disease, or who may have connective tissue disease or other features that would make them more at risk of developing pulmonary arterial hypertension than the rest of the population. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Follow us on social @phaware Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com #phawareMD @VUMCDiscoveries @pphnet @VUMCchildren

Sandra M. Oliver-McNeil, DNP, ACNP-BC, FACC, JACC: Case Reports Deputy Editor, is joined by author Liam S. Flanagan, MD discussing this study from Flanagan et al presented at ACC.25 and published in JACC: Case Reports. Pulmonary arterial hypertension (PAH) has a diverse range of etiologies and carries significant morbidity and mortality. Here, a 45-year-old female presented with shortness of breath and was found to be in acute right heart failure due to PAH. Exam demonstrated features of scurvy. She initially required vasopressors, supplemental oxygen therapy, and PAH therapies but rapidly improved with vitamin C supplementation.

Returning for a second study this month, the JHLT Digital Media Editors conduct an internal discussion on the paper, “Safety and efficacy of riociguat in patients with pulmonary arterial hypertension and cardiometabolic comorbidities: Data from interventional clinical trials.”   The episode explores: The aging PAH population and the new comorbidities that must be considered in research How the study augments and expands on recent standards, like the 2022 ESC/ERS guidelines for pulmonary hypertension Limitations on the study and opportunities for future research For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.   Those on lung transplant teams should check the previous episode for a study on how rewarming ischemia time affects lung transplant outcomes.   Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.  

This CME program, hosted by Jean Elwing, MD, of the University of Cincinnati College of Medicine provides an overview of the latest clinical research about PAH presented at CHEST 2024.PAH is a rare, progressive disorder characterized by high blood pressure in the pulmonary arteries. Symptoms of PAH include shortness of breath (dyspnea) especially during exercise, chest pain, and fainting episodes. The progressive nature of this disease means that an individual may experience only mild symptoms at first, but will eventually require treatment and medical care to maintain a reasonable quality of life. There are numerous treatment options and options in development for persons with PAH and it is imperative clinicians who manage these patients stay up-to-date on the latest clinical research. Target AudienceThis activity has been designed to meet the educational needs of physicians specializing in pulmonology, cardiology, rheumatology, and radiology. Other members of the care team may also participate.Learning ObjectivesDescribe the latest research being presented to better manage people with PAH and its clinical relevance.CME CreditTo obtain credit, visit https://checkrare.com/learning/p-pah-clinical-research-highlights-chest-2024/Faculty/ DisclosureAccording to the disclosure policy of the Academy, all faculty, planning committee members, editors, managers and other individuals who are in a position to control content are required to disclose any relationships with any ineligible company(ies). The existence of these relationships is not viewed as implying bias or decreasing the value of the activity. Clinical content has been reviewed for fair balance and scientific objectivity, and all of the relevant financial relationships listed for these individuals have been mitigated.Disclosure of relevant financial relationships are as follows:Dr. Elwing discloses the following relevant financial relationships with ineligible companies:Advisory Board Consultant: United Therapeutics, Aerovate Therapeutics, Gossamer Bio, Liquidia, Merck, Janssen/Actelion/Johnson & Johnson, Lung LLC, PulmovantGrant/Research Support: United Therapeutics, Gossamer Bio, Bayer, Acceleron/Merck, Altavant Sciences, Aerovate Therapeutics, Pharmosa Biopharm/Liquidia, Actelion/Janssen/Johnson & Johnson, Lung LLC, PulmovantSpeaking Honorarium: United TherapeuticsPlanners for this activity have no relevant financial relationships with any ineligible companies.This activity will review off-label or investigational information.The opinions expressed in this educational activity are those of the faculty, and do not represent those of the Academy or CheckRare CE. This activity is intended as a supplement to existing knowledge, published information, and practice guidelines. Learners should appraise the information presented critically and draw conclusions only after careful consideration of all available scientific information.Accreditation and Credit DesignationIn support of improving patient care, this activity has been planned and implemented by American Academy of CME, Inc. and CheckRare CE. American Academy of CME, Inc. is Jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.PhysiciansAmerican Academy of CME, Inc., designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Other HCPsOther members of the care team will receive a certificate of participation.PrivacyFor more information about the American Academy of CME privacy policy, please access http://www.academycme.org/privacy.htm  For more information about CheckRare's privacy policy, please access https://checkrare.com/privacy/ContactPlease contact: CEServices@academycme.org for any comments or questions.;Copyright © 2025. This CME-certified activity is held as copyrighted © by American Academy of CME and CheckRare CE. Through this notice, the Academy and CheckRare CE grant permission of its use for educational purposes only. These materials may not be used, in whole or in part, for any commercial purposes without prior permission in writing from the copyright owner(s).

On this episode of JHLT: The Podcast, the Digital Media Editors invite lead author Jan Van Slambrouck, MD, to discuss the paper, “The effect of rewarming ischemia on tissue transcriptome and metabolome signatures: A clinical observational study in lung transplantation.”   Dr. Van Slambrouck is a general surgeon who's just finished his PhD training at the KU Leuven lab of respiratory disease and thoracic surgery in Belgium.   The episode explores:  How rewarming ischemia time (RIT) affects donor lungs, especially on the molecular level The pace of rewarming and how prior literature prepared the team to track and evaluate it Clinical strategies to reduce RIT and directly address molecular changes   For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.   Those involved in the pulmonary vascular disease space should tune in again later this month for a study on the safety and efficacy of riociguat in patients with PAH.   Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

Jen Cueva, a pulmonary hypertension patient of almost two decades, discusses her diagnosis, her advocacy work, and how she uses writing to support the pulmonary hypertension community. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com. @PulmonaryNews

Canadian resident, Stephen Gariepy, was diagnosed with Chronic Thromboembolic Pulmonary Hypertension (CTEPH) in 2018. After initially being active in senior hockey, his condition worsened, leading to difficulty breathing and performing daily tasks. Gariepy continues to live with this rare and terminal disease, adapting to the limitations it imposes on his daily life. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com. @phacanada 

On this episode, we evaluate current guidelines and evidence-based treatment strategies for managing pulmonary arterial hypertension. We compare and contrast the efficacy, safety profiles, and appropriate use of targeted PAH therapies, adjunct treatments, and patient monitoring techniques.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the following link below to go to freeCE's website: https://www.freece.com/ If you're not currently a freeCE member, we definitely suggest you explore all the benefits of their Unlimited Membership on their website and earn CE for listening to this podcast. Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. If you purchase an annual membership, you'll also get a free digital copy of High-Powered Medicine 3rd edition by Dr. Alex Poppen, PharmD. HPM is a book/website database of summaries for over 150 landmark clinical trials.You can visit our Patreon page at the website below:  www.patreon.com/corconsultrx We want to give a big thanks to Dr. Alex Poppen, PharmD and High-Powered Medicine for sponsoring the podcast..  You can get a copy of HPM at the links below:  Purchase a subscription or PDF copy - https://highpoweredmedicine.com/ Purchase the paperback and hardcover - Barnes and Noble website We want to say thank you to our sponsor, Pyrls. Try out their drug information app today. Visit the website below for a free trial: www.pyrls.com/corconsultrx We also want to thank our sponsor Freed AI. Freed is an AI scribe that listens, prepares your SOAP notes, and writes patient instructions. Charting is done before your patient walks out of the room. You can try 10 notes for free and after that it only costs $99/month. Visit the website below for more information: https://www.getfreed.ai/  If you have any questions for Cole or me, reach out to us via e-mail: Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com

In ep 108 of “How Do You Say That?!” sponsored by britishvoiceover.co.uk, Melissa Sinden joins Sam and Mark to talk about the irony of being asked to play an AI voice, how sessions with lots of people involved can get quite unruly, and how to sound natural when you're playing the part of a voice actor!Our VO question this week is all about how you create a rounded, three-dimensional character for animation.Get involved! Have you got a Wildcard suggestion that we should try or an idea for the show? Send it to us via Mark or Sam's social media or email it directly to podcast@britishvoiceover.co.ukScript 1Right... I'm just getting my characterisation sorted... do you want to hear my thoughts? So, with the main course... our seven nut ‘nut' roast... I'm thinking I'm a nut connoisseur, but I not only embrace the taste of the nuts, but I also travel to where they're produced and soak in the local culture, which gives me an insight into the source of their taste... and as for the vegetables... they'll be picked by students on summer vacation, working on organic farms in Norfolk... they'll be first and maybe second year students, from all around the world... How does that sound?Script 2MVO: (vintage style) In my day motor vehicles had keys not buttons and they didn't need plugging in! When you get a ding, dent, chip or scratch in your techo Tesla, who can repair it now ask! Robots? Pah.FVO: (modern voice of a smart AI) Prestige cars can be repaired at A and B Vehicle repairs. They are manufacturer approved for Audi, Mercedes, BMW and now also Tesla. Does that answer your question?MVO: Who said that? what witchery is this?!FVO: Go direct to A and B Vehicle Repairs; where accidents unhappen.We'd love your feedback - and if you listen on Apple Podcasts or Spotify, hit the follow button today!**Listen to all of our podcasts here - you can also watch on YouTube, or say to your smart speaker "Play How Do You Say That?!"About our guest: Melissa is the child of a pair of opera singers and has been a voice actor for many years - despite being only 39!! She trained as an actor but went straight into voicing.As well as corporate and commercial, she was also an animation voice - Jess the Cat's meow in Postman Pat as well as Strange Hill High, Little Monsters AND a background clucker in the first Chicken Run film! Melissa has also done tons of radio drama over the years as well as BBC Radio 4 short stories, book extracts and poems. Melissa finally went back into in vision acting about 15 years ago - programmes like Shameless, Brassic, Vera, Corrie and Emmerdale, as well as theatre and she writes and does public speaking gigs! Melissa's VocalPoint Website Resources: Click here for the Wildcard Generator and don't forget to think of an action your character can be doing!Mark's demos & contact details:

Jolie Lizana is a pulmonary hypertension (PH) survivor and advocate. Despite enduring severe heart failure and lengthy hospitalizations, Jolie credits her medical background, determination, and the love for her child for pushing her to survive and adapt. Jolie now raises awareness through her website, www.breathtakingawareness.com, and has contributed to creating EMS protocols for PH patients, showing her dedication to empowering others with hope and resources. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com.

Allison Feenstra shares her transformative journey from being an active, independent young woman to navigating life with pulmonary hypertension (PH). She recounts how a sudden blackout led to hospital visits and the discovery of the condition, stemming from complications related to prolonged bed rest and birth control medication. Allison candidly discusses how she underwent a significant surgery and persevered through a high-risk pregnancy, ultimately becoming a mother. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com. @phacanada

Welcome, weary adventurers, to another celestial installment of the RPGBOT.Podcast! In this episode, our hosts take a divine deep dive into the luminous layers of Mount Celestia, the lawful good paradise of the D&D multiverse, where angelic beings reign supreme, the paperwork never stops, and even heaven has a dress code. Links 2014 Dungeon Master's Guide (affiliate link) 2024 Dungeon Master's Guide (affiliate link) Mordenkainen's Tome of Foes (affiliate link) Forgotten Realms Wiki - Celestia The Roof is on Fire The Bad Touch What's Inside This Episode? Prepare for an unholy amount of lawful good as our hosts grapple with questions like: Is Mount Celestia just an exclusive afterlife country club? The ultimate "gated community," where only the most virtuous souls get a keycard and an HOA compliance form. Do Celestials ever take a break? Or are they stuck in an eternal grind to keep their goodness rating at a solid 10/10? Why does the seventh layer feel like the VIP lounge of the cosmos? No one comes back to tell the tale—are they ascending to ultimate bliss or just getting locked in divine HR meetings forever? Is Bahamut's realm the fantasy equivalent of an armored Renaissance Faire? A blend of knightly virtue, dragon-sized bureaucracy, and the world's most rigid chivalry standards. What's with the mysterious black domes? Are they heavenly zen gardens or celestial prisons? And why do they sound like the plot of a horror movie? Heaven, but Make It Complicated The discussion takes unexpected turns as the hosts compare D&D's Mount Celestia with Pathfinder's Heaven, exploring celestial beings, alignment shenanigans, and the sheer logistics of running a flawless divine realm (spoiler: it's harder than it looks). From beachfront property in the first layer to the moral implications of ascending through good deeds, the conversation proves that even perfection has a few cracks. But wait, there's more! Comedic interludes featuring celestial court jesters, the trials of divine pronunciation (is it Pay-lore or Pah-lore?), and the baffling existence of heavenly bouncers. A light roasting of the celestial bureaucracy, because even angels probably have to fill out divine TPS reports. A deep-dive into morality, questioning whether lawful good is just neutral good with extra paperwork. Final Verdict? Celestia might be a beacon of goodness, but our hosts aren't convinced it's the paradise it claims to be. Between the divine bureaucracy, alignment gatekeeping, and oddly exclusive policies, they make a compelling case for why sometimes, chaotic neutral might be the way to go. Tune in to this hilariously insightful episode where philosophy meets comedy, and the afterlife gets a much-needed reality check! If you enjoy the show, please rate and review us on Apple Podcasts, Spotify, or your favorite podcast app. It's a quick, free way to support the podcast, and helps us reach new listeners. If you love the show, consider joining us on Patreon, where backers at the $5 and above tiers get ad free access to RPGBOT.net and the RPGBOT.Podcast, can chat directly to members of the RPGBOT team and community on the RPGBOT.Discord, and can join us for live-streamed recordings. Support us on Amazon.com when you purchase products recommended in the show at the following link: https://amzn.to/3NwElxQ How to Find Us: In-depth articles, guides, handbooks, reviews, news on Tabletop Role Playing at RPGBOT.net Tyler Kamstra Twitter: @RPGBOTDOTNET Facebook: rpgbotbotdotnet Bluesky:rpgbot.bsky.social Ash Ely Professional Game Master on StartPlaying.Games Twitter: @GravenAshes YouTube@ashravenmedia Randall James @JackAmateur Amateurjack.com Producer Dan @Lzr_illuminati  

Welcome, weary adventurers, to another celestial installment of the RPGBOT.Podcast! In this episode, our hosts take a divine deep dive into the luminous layers of Mount Celestia, the lawful good paradise of the D&D multiverse, where angelic beings reign supreme, the paperwork never stops, and even heaven has a dress code. Links 2014 Dungeon Master's Guide (affiliate link) 2024 Dungeon Master's Guide (affiliate link) Mordenkainen's Tome of Foes (affiliate link) Forgotten Realms Wiki - Celestia The Roof is on Fire The Bad Touch What's Inside This Episode? Prepare for an unholy amount of lawful good as our hosts grapple with questions like: Is Mount Celestia just an exclusive afterlife country club? The ultimate "gated community," where only the most virtuous souls get a keycard and an HOA compliance form. Do Celestials ever take a break? Or are they stuck in an eternal grind to keep their goodness rating at a solid 10/10? Why does the seventh layer feel like the VIP lounge of the cosmos? No one comes back to tell the tale—are they ascending to ultimate bliss or just getting locked in divine HR meetings forever? Is Bahamut's realm the fantasy equivalent of an armored Renaissance Faire? A blend of knightly virtue, dragon-sized bureaucracy, and the world's most rigid chivalry standards. What's with the mysterious black domes? Are they heavenly zen gardens or celestial prisons? And why do they sound like the plot of a horror movie? Heaven, but Make It Complicated The discussion takes unexpected turns as the hosts compare D&D's Mount Celestia with Pathfinder's Heaven, exploring celestial beings, alignment shenanigans, and the sheer logistics of running a flawless divine realm (spoiler: it's harder than it looks). From beachfront property in the first layer to the moral implications of ascending through good deeds, the conversation proves that even perfection has a few cracks. But wait, there's more! Comedic interludes featuring celestial court jesters, the trials of divine pronunciation (is it Pay-lore or Pah-lore?), and the baffling existence of heavenly bouncers. A light roasting of the celestial bureaucracy, because even angels probably have to fill out divine TPS reports. A deep-dive into morality, questioning whether lawful good is just neutral good with extra paperwork. Final Verdict? Celestia might be a beacon of goodness, but our hosts aren't convinced it's the paradise it claims to be. Between the divine bureaucracy, alignment gatekeeping, and oddly exclusive policies, they make a compelling case for why sometimes, chaotic neutral might be the way to go. Tune in to this hilariously insightful episode where philosophy meets comedy, and the afterlife gets a much-needed reality check! If you enjoy the show, please rate and review us on Apple Podcasts, Spotify, or your favorite podcast app. It's a quick, free way to support the podcast, and helps us reach new listeners. If you love the show, consider joining us on Patreon, where backers at the $5 and above tiers get ad free access to RPGBOT.net and the RPGBOT.Podcast, can chat directly to members of the RPGBOT team and community on the RPGBOT.Discord, and can join us for live-streamed recordings. Support us on Amazon.com when you purchase products recommended in the show at the following link: https://amzn.to/3NwElxQ How to Find Us: In-depth articles, guides, handbooks, reviews, news on Tabletop Role Playing at RPGBOT.net Tyler Kamstra Twitter: @RPGBOTDOTNET Facebook: rpgbotbotdotnet Bluesky:rpgbot.bsky.social Ash Ely Professional Game Master on StartPlaying.Games Twitter: @GravenAshes YouTube@ashravenmedia Randall James @JackAmateur Amateurjack.com Producer Dan @Lzr_illuminati  

On the 28th anniversary of her PH diagnosis, Jodi Berry shares her journey of living with pulmonary hypertension. Despite facing an initial prognosis of only a few years to live, Jodi's determination and the support of her family, friends, and healthcare professionals helped her manage her condition while maintaining an active lifestyle. Over time, advancements in treatments and her proactive participation in clinical trials provided hope and improved her quality of life. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com. @phacanada

Nurse Practitioner, Janette Reyes, from the Pulmonary Hypertension Program at the Hospital for Sick Children shares her extensive experience caring for pediatric patients with pulmonary hypertension. Reyes discusses the unique challenges and developmental considerations involved in treating children from infancy through their teenage years, as they transition to adulthood. Reyes also touches on the emotional and social struggles these young patients face, such as bullying and anxiety, and highlights the role of the multidisciplinary team in supporting their mental well-being. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com. @phacanada

Taliyah.Based on a post by FinalStand, in 13 parts. Listen to the ► Podcast at Explicit Novels. By lunchtime, she was beginning to feel somewhat selfish. Mikhail had been attentive with a totally unexpected devotion all morning long. While Taliyah was emotionally conflicted about her parent's most recent feuding, it was systematic of a much deeper rift she'd always felt among them. She'd always sensed it; as if something was missing in their lives.To be honest with herself, at first she'd been secretly pleased when Brandy's home life had imploded last summer. Not only had she found herself lusting for Darius over Rashaan, she'd long been envious of the seeming closeness between Big Bob and Jodi May. She'd felt furtive elation when Brandy's mom eloped with Senior Deputy Jenks, shattering the illusion of their happy household.Only later, as she saw the daily sadness in Big Bob, had she begun to regret her envy-driven vindictiveness. Unlike her own, rather distant Father, Big Bob Carson had always made Taliyah welcome in his home and with his daughter. His treatment of her had never jibed with the claims about the White man's supposed racism. In her home, they joked about him, yet she'd never heard Big Bob make a single racist slur in her presence.No, Brandy's Dad had treated her like his second daughter; even going so far to call out Brandy when she was being a bitch to her. As far back as elementary school, he'd made her feel as if Taliyah had a second house to call home; and then Taliyah had repaid his repeated kindness by taking perverse pleasure as his home fell apart. She'd watched Brandy fall into depravity under Darius' spell and said nothing.Taliyah wondered about the vagaries of karma. Brandy's family had been ripped apart and now so was hers. Brandy had found Vlad and now she had Mikhail. This morning, Brandy's mom had come back; and her Mom was here as well. But her Father was nowhere in evidence. Her Mother, Madam Mayor, hadn't mentioned him once.‘Taliyah,' Kaelyne disturbed her ruminations, ‘we're picking sides for volleyball.'Kaelyne was another transformative presence who had snuck into her life as of late. Her knee-jerk reaction when learning the little White girl had a lesbian crush on her was to lash out and mock her. That had infuriated Mrs. Samsonov, pain had rapidly followed. That old White bitch had forced Taliyah to apologize the next day.Over the rest of the following week Taliyah had found herself studying the way Kaelyne looked at her; and hadn't been repulsed. Still, until today she hadn't taken the lesbian's affections seriously. Kaelyne was sensitive to Taliyah's pain and~ compassionate without being obtrusive. Taliyah had responded with a lessening of her often acidic wit.With Brandy taking on solo duties as hostess, Taliyah had been able to recoup in the company of her boyfriend; and 'girlfriend'; thus the source of her guilt. According to Mrs. Samsonov's plan, Brandy and Taliyah had to share their guys with the rest of the Cheer Squad over the course of the day.From what they'd been told, it would keep the cheerleaders firmly out of the hands of the Football Team and other member of the 'Cult of the BBC'; as that racist, psychotic bitch, Gayle Samsonov, called it. And, from what Taliyah and Brandy could see, it made all the ones who had been with their fellas so far want them and only them; it was spooky and somewhat frustrating to watch because Mikhail was her man, damn it!Not in the way Rashaan had been her man because Rashaan hadn't even been his own man, just another pawn of Darius Pope's little high school empire; like her and Brandy. Maybe that was why she was so drawn to the youngest triplet's fierce independence. He was harder to influence than Rashaan had been; which wasn't quite so.She could, in private, convince Rashaan to do things, plan things and stand up for himself, but all the results of her efforts evaporated when he was around Darius; and now she realized that would always be the case for someone like Rashaan. He was good looking and could project leadership, but there was never anything behind it. No drive. No great willpower to overcome any real opposition; and most likely, there never would be.With Mikhail; God! He was so different. Sure he was infuriating, but Taliyah found herself able to cut loose around him; to pop him one when she felt he was doing something stupid; and it wasn't as if he even minded. Oh no, that didn't mean he'd acquiesce, far from it. Normally he'd laugh and evade, taunting her. Yet, that was the way he'd grown up around his brothers and Taliyah was beginning to figure out he was allowing her to treat him the same way; that was was something special.He and his brothers were rough-n-tumble. They had a code for their fighting. While their Code didn't make the inevitable conflicts any less brutal, it at the same time expressed ample fair play, honesty and integrity. And afterwards; there was never any ill will between them. They fought and shit got settled; and Taliyah liked that. That Mikhail allowed her to lay into him was, according to his Mamma, very intimate and personal; and Taliyah was coming to appreciate this fact.‘Mikhail, why don't you and Kaelyne teach my 'Sisters' on the Cheer Squad some manners,' she touched his hand. They were side by side at the counter in the kitchen, him finishing off a few carrot slices while she drank some Gatorade. ‘I need to talk to my Mamma; alone.' Mikhail gave her a brief eye contact, nodded once, and then turned to leave.‘Kaelyne,' she found herself reaching out, stroking the girl's cheek and rubbing her earlobe, ‘Thank you.' The way the smaller woman positively glowed gave Taliyah a spike of pride. She still didn't think she was into girls, but she'd been showering with Brandy since before they were teenagers. A few times Brandy had ran her hands curiously over her darker friend's skin, wishing she tanned so well.In turn, Taliyah had run her hands through Brandy's long, blonde hair, feeling the difference between its silky texture and her own, coarser locks and wishing her hair was so easy to manage. The two girls, lifelong friends, had never considered their behavior anything which 'made them gay'. They were curious and comfortable in each other's presence was all.Taliyah pushed herself away from the counter, turned and dismounted her stool. She'd put up a wall against the World all morning long and she knew she was better than that. She'd wanted her Mother to come and talk to her; to talk to her about her Father; her Mother's husband; and what she was going to do about fixing things. Her Mamma was always the responsible one in the family and had taught her daughter to be the same way. Somehow; her Mamma had to make this right.Le ‘Pearl' Yates.For Le it had been a wild, chaotic week. Things had started out so bad, but not in a way the other girls in the Cheer Squad would have understood. Monday morning, like most of the others; except Brandy and Taliyah; she had been seriously jonesing for some BBC. Hell, unlike every other member of the squad, getting the best cock was why she'd fought so hard to be selected as one of the school's elite bitches in the first place.She hadn't always been that way.Le had been a late bloomer. Worse, she'd never been part of any crowd while growing up. Her Vietnamese-American Mother had come to Kingston from the Texas Gulf Coast to be a nurse. Her Father, the White guy her Mother married, was an oilman working in the Gulf of Mexico months at the time.He was really happy when his wife told him she was pregnant. His company even flew him to Arkansas when she went into delivery early. Let's just say his reaction when he held 'his' daughter wasn't all that joyous. He divorced her a year later and Le had only seen him a few times since. Things had been; tense.It took her a few years to figure out she wasn't like anyone else. Her Mother's extended family, fisher-folk back in Texas, always treated her badly and the younger ones called her names, which was why her Mom had returned to Kingston after a few years. When she was six, she finally figured out she was a 'half-breed' and not in a 'good way'. No White blood had 'watered' down her complexion.Her eyes were product of her Mother's Vietnamese heritage while her nose was from West Africa. He skin was darker than her Mother's, not lighter, and she was much taller, at 5'9', and a compact 112 lbs. Her ass was 'black enough', but her chest was 'too Asian' as in she clearly had the smallest bra size on the team.At the age of eight she'd finally asked her rather traditional Mother who her 'real' Daddy was. On her twelfth birthday, her Mother, after years of badgering, finally broke down and told Le the story. She'd been 'seduced' by a groundsman on the A S U Kingston campus while her 'White' Daddy had been away for months and months at sea. He'd been a smooth operator, her Mother told her.'But why isn't that man my Father now?' she'd pressed her Mother. She'd graduated to referring to the nebulous sperm donor as Father when she was ten. Her Mother hung her head in shame then confessed the Black bastard hadn't wanted her. When she'd told him she was pregnant with what was most likely his child, he'd seemed happy at first.Only as she got 'bigger', things had changed. One day she stumbled upon him cheating with another nursing student. She'd exploded in tears. After the 'new' girl had fled, he 'confessed' he had yet another girl pregnant and two other kids by two other women; and it was over between them. He dumped her.So, her Mother had prayed somehow Le would be born without her White Father figuring out her betrayal; but that hadn't worked out either. She even gave Le the sperm donor's name, Claude Sexton. It turned out Le had sixteen half-brothers and –sisters (by five different women) and he was currently serving time in prison for pharmaceutical theft. Claude's Mamma, her Granny, claimed he was 'not guilty' and some jealous bitch (usually White in her rantings) had set him up;What had fascinated Le though was the 'why' of her Mother's betrayal of her White 'Father'. The few times she'd met him he'd seemed nice. He had remarried, still made good money and had two other, White, children these days. He had never been cruel to her Mother as far as her Mother had ever revealed; so why had she jumped on some Black cock and risked such a profitable union?At the age of twelve, Le was still gangly and under-developed. Puberty was late to the party. Shortly after her Mom's revelation, she began looking at the Black boys at school differently. They were still going from the phase of teasing and bullying girls (and being teased and bullied by some of the bigger girls) to sending the ladies looks of hungry confusion.No guys ever looked at Le that way back then; but suddenly she wanted them to. When she entered High School, she was 'introduced' to the Cheer Squad / Football Team dynamic. All the hottest Black guys and most beautiful girls (Black and White) belonged to that top social tier; and she had no hope of getting in the way she was.She also had another niggling problem. She was smart and unfortunately, smart girls were Not what those two groups were looking for.But, Le had a Plan. First off, she took up a paper route to make enough money to join the Dance School; because the Cheerleaders always seemed to pick the Hot girls with dance experience; and her Mother couldn't afford to send her with what she made.Secondly, she began purposely getting 25 to 35% of all her homework and test answers wrong. Le had to lower her academic profile starting her freshman year so hopefully no one would remember how smart she had been in Middle School. She added to this deception by telling everyone her name was 'Pearl', even the teachers, and always wearing long pig tails because she thought it fed into the ‘Cutesy' Asian stereotype; and they bought it.Lastly, she began working on her physique and fashion sense to make herself more noticeable to the people who really mattered. Her body's natural development helped. Belatedly her hormones kicked in and her breast began to get bigger. Of equal importance, with all her exercise and dedication her 'lower chasse' began getting the boy's notice. When their eyes finally got to her face, they also noticed how exotically different she was.She enjoyed the first touching; and kissing. She also knew the unspoken rules: Don't be a skank and put out for just anybody. The Football Team only selected the most choice ladies and that included the ones they didn't consider 'total whores'; thus their exclusive property.She lucked out by having Randi Leigh Upshaw befriend her. Randi Leigh's mother had been a cheerleader back in the day and was currently a school booster and member of the PTA. Sure, Randi Leigh was a condescending, manipulative bitch, but she opened doors into social circles which would have been far harder to breach as an outsider.And all that degradation and hard work had paid off when the old Cheer Squad Team Captain handed her a cheer uniform, welcomed her to the team and then introduced her to her first gang-bang. Five long hours afterwards, the smiling Captain gave her a 'Morning After' pill and told her were to go to get her I U D. She'd been taking BBC five / six times a week ever since and loving it; her Mother's infidelity finally understood.Until, for some bizarre reason, Brandy and Taliyah, this year's Co-Captains, had decided to launch an utterly unlooked for and unwanted rebellion against Darius Pope; Football God and one of the best cocks on the team. Le had been blind-sided, as had all of the other cheerleaders. The only two questions were how much hell was Darius going to put those two through for their impertinence and who would end up in the top spot once he was done.But then Darius and six other footballers (including two of the other best cocks in Le's estimation) were destroyed in the school parking lot after a game. Her whole world appeared to crumble and changed. Randi Leigh; idiotically; threw herself at Rashaan as if he could somehow assume Darius' mantle. Le initially supported her because at least Randi Leigh promised a return to the glorious days of orgies and bukkake cum baths.Wednesday morning, it hadn't taken a telepath, or that guy from Psych, to figure out something serious had happened to both Randi Leigh and Sultana (the other challenger). Randi Leigh couldn't even keep Betty Jo Sterling (her other supporter) in line and poor Betty Jo was easily amused by a laser pointer and kitten emojis for God's sake!All that led to her being highly suspicious of Taliyah luring her, Vantrice Kirby and Mia Ryker to the Music Room during Lunch Thursday. Taliyah had told them the whole team was meeting yet when Le surreptitiously checked her iPhone App, only Brandy's phone was close by. She was actually kind of terrified some sort of beat-down was in the offing when they stumbled in and found;; Mikhail and Vlad Samsonov reclining on the piano cover with a sexual sated; no, devastated, Brandy Crystal Carson curled up between them. Le knew what 'fucked stupid' looked like and Brandy definitely qualified. Vantrice and Mia began protesting (these 'boys' weren't on the Football Team). Le was busy putting 'A' together with 'B' then 'C'.In this case: (A) Brandy and Taliyah's sudden defiance, (B) Randi Leigh and Sultana's sudden cessation of (serious) resistance and now (C) Brandy's obvious physical pleasure radiating out for all to see. Le's ever-present blow-pop nearly fell out of her mouth in shock. Whatever her other two teammates (Vantrice and Mia) were thinking, Le knew she had to have 'some of that'.‘Which one is for me?' she had turned to Taliyah, her carefully crafted 'silly little Asian girl' façade momentarily slipping. Taliyah grinned like the sly fox she thought she was.‘Mikhail is mine, but I can share,' she purred as she began to strip. Even as she joined Taliyah in removing her clothing, Le did her own eyeball math. Mikhail was definitely more intrigued with Vantrice than either her, or Mia.How did she know the difference between the two triplets? Well, anyone who thought it was Mikhail beaten up by Darius' people, not Alexander, was a fool. Darius wouldn't have made that error. Otherwise, Mikhail was looking at them like a starving wolf staring at pieces of meat; or sheep. Vlad's eyes kept flickering down to Brandy in something a less romantic person could confuse with love. She headed toward Vlad.‘Can you make me happy like Brandy?' Le sashayed toward the middle triplet, socially shedding 60 IQ points along the way. Boys liked them dumb, right?‘Le,' he smiled; not leered, ‘I think I can make you your own kind of happy,' he volleyed back. Okay, that second part was kind of sappy, but he actually recalled her real first name which hadn't happened in over a year.‘Pearl, stop that,' Vantrice got indignant. ‘These White boys; ‘‘I want to look like Brandy,' Le looked over her shoulder. ‘Don't you?'Vantrice stuttered, Mia was indecisive, Taliyah clearly wasn't going to let them bolt without a struggle and Mikhail was closing in to help.‘Sorry Mia, but I have a hunger for Black chicks,' he moved the blonde aside.‘What?' from Mia.‘Huh?' from Vantrice and;‘Best watch yourself, Mister,' from Taliyah, all aimed at Mikhail. Le opted to focus on Vlad who was certainly fixated on her.‘I want to taste,' she settled down beside him, reaching for his delicious looking piece of man-meat.‘How about we '69'?' he offered.‘I like the way you think,' she glowed. Normally they didn't give her the option. Le put her blow-pop on a desk then went to work.‘Eep!' she squeaked as he effortlessly picked her up and laid her out beside Brandy. He took a few licks of her vulva then;‘Mia, come over here,' he beckoned the blonde girl who seemed to be at loose ends. Le was too busy exploring the texture and taste of his glans and shaft. It was her first White cock; she'd had thicker; yet she felt it would be more than enough to satisfy if Vlad's stamina equaled his dimensions;‘Lay down beside her,' Vlad had directed Mia. She still seemed uncertain and Le wanted to keep Vlad happy for the nonce, so she reached up, took Mia by the hand and gently pulled her to her side.‘Ah; ‘ Mia began purring. Vlad must have been physically stimulating her with his right hand even as his mouth and left hand pleasured her. Damn; Vlad knew his stuff.The real magic began when, after she let him know she was ready; which had always been the reason for guys going down on her, to get her engine running; Vlad had gone to town on her cunt. He licked, tongue-twirled and nibbled her clit, put three fingers into her snatch and, after some teasing, another in her ass. She'd never had a guy pet her G-spot before, but Vlad did.Her inarticulate utterances weren't new, but more protracted than she was used to. She recovered quickly, yet not quickly enough to stop her new lover from moving on to Mia who gladly let him go down on her as well. Le had propped herself up and begun to look around when she noticed a reclining Brandy studying the three of them.‘That felt nice, really nice,' she communicated after a few seconds.‘Don't I know it,' Brandy sighed. She didn't seem to be unhappy with her, or Vlad. There was a pregnant pause as Vlad continued to devote himself to Mia's gratification. ‘All three triplets are wonderful, but I think I've got the best one.'‘Are we ever going to be with the Football Team again?' Le'd wondered.‘Hmmm; ‘ Brandy frowned then, ‘Vlad, Pearl isn't convinced.'And then he'd gone and 'convinced' her, which had been odd. For a moment, when he returned to her, he'd seemed distracted, or put out. Once he made eye contact, Le felt as if their whole world contracted down to just the two of them.Or that was how it had been recalled by Le later as she tried to remember every erotic murmur, sensuous movement, whispered word and tantalizing slap of flesh against flesh. They hadn't fucked. They had made love and until Vlad, she hadn't know the difference. It was sex; but with the difference being she felt he really gave a damn, and not only about how she felt right then, but how she felt, period. It had been so different; and exciting; and so worth repeating.Which brought her back to today, at Brandy's house, playing around the pool and trying not to pull Vlad aside for another round of whatever he had done to her. Le had been trying to figure out this new pecking order and how to best profit from it. She wasn't so egotistical she thought she could steal Vlad away from Brandy; she accepted Brandy had more of the feminine traits which drew Vlad's eyes.Then there was the ravenous way Randi Leigh regarded the young man when she thought Brandy wasn't keeping an eye on her. The way Betty Jo and Alondra teased him was even;‘You spend a whole bunch of time watching what other people are doing,' was whispered into her ear. Le nearly tumbled off the recliner she'd been using.She was able to catch her blow-pop before it fell out of her mouth with judicious use of her lips thus buying her a little more time and stopping her from gasping in fear. Mrs. Samsonov had snuck up on her.‘Ma; Ma; Mrs. Samsonov? Huh?' she was a bit too slow on the comeback.‘You can call me Gayle,' the crouched, mature lady regarded her; much like a feral cat gazing at a frightened field mouse.‘Ah; okay, Gayle,' she hammed it up with a cute tilt of the head. The older woman's eyes narrowed.‘I am beginning to think you aren't quite as dumb as you pretend to be,' Gayle murmured. ‘Now why would that be?'‘What be?' Le played along. Mrs. Samsonov's look became downright menacing.‘I don't like being played for the fool,' she whispered. ‘I'm real sure Vlad and his brothers will be even less amused.'Then, in a flash, the triplet's mother stood and smiled down at her, though Le could sense the humor didn't touch her eyes, or her words. ‘Have fun this weekend, Pearl. Act dumb around school if you like, but my children and I don't have time for such games.'‘I; Mrs.; Gayle, why; how did you figure it out?' Le's protests went from lame to a whisper. When denial was clearly no longer an option, she wanted to know what she'd done to give herself away.Gayle studied her for a few; very long; seconds.‘Smart people can act stupid, but stupid people can't act smart. That being said, really dumb people have bad body posture, often have their mouths open when they don't know what to say; not your candy; and don't react when they themselves say stupid shit,' Gayle enlightened her.‘You make simple statements, but not stupid ones; like Alondra and Betty Jo do. They stay stupid things while you don't. True, they are dumber than most, but they are the ones you are trying to model yourself after, failing, and failing in a manner a suitably observant person can pick up on. After all, for the past two years, how many guys, or girls, have wanted to test your conversational skills?'Le was taken aback at how helpful the older lady was and began taking mental notes.‘Are you; how angry are you with me?' Le worried.‘We accept you've had to deal with different social factors at Davis Consolidated (High School) before we came here. Choices you made last year and before now are in the past. If you don't want to learn from your mistakes, that's on you.'‘If we change?'‘You are no longer cum dumps for the Football Teams. You are the Supreme Female Social Organization with the Samsonov boys making sure you won't be abused, or used as sexual trophies.‘But there still will be sex?' Le gulped. Gayle Samsonov's countenance was downright savage.‘Would you do every member of the Football Team, or just my Vlad?' she posed the question (trap). Le really liked the Football gangbangs, blowjobs and bukkake sessions. Her hunger to embrace the madness which had turned her Mother away from her (White) Father and brought her (Le) into existence came into conflict with her desire to recapture the personal experience she'd shared with Vlad.‘Isn't he mostly interested in Brandy?'‘He's devoted to Brandy, but Brandy will let him spend time with you as long as you support Brandy and Taliyah; plus you keep Vlad's interest because it is the right thing to do,' Mrs. Samsonov explained. Le wasn't used to thinking of either Brandy, or Taliyah, as magnanimous, except;‘Do Brandy and Taliyah confide in you?' Le made an educated leap. Of course, Taliyah's mother was opposed to all things Fonteneau; but here she was, chaperoning the same party, and Brandy had been utterly under Darius' spell at the start of the year; yet clearly was now madly devoted to Gayle's middle son.Gayle's grin lost some of its hostile quality.‘Clever indeed.'Le gave a shy smile in response.‘Enjoy the weekend, Pearl. Open up to Vlad if you get the chance. He's not intimidated by smart women, he likes reading; not as much as sex, but he's still happy to learn; and teach,' Gayle imparted. As she walked away, Le had to wonder how her whole world had transformed; no; evolved. She hoped it was evolving into something much more intriguing than what they were all surrendering. She jumped up and ran to catch up with the older woman. There was so much more she could learn.Victoria ‘Mad Vicky' Orem.‘Come on, Alexander, join us beating up these cheerleader-bitches,' Vicky pleaded with the oldest Samsonov triplet. She'd scampered over to him because her team needed the help and she wasn't sure Kaelyne would be able to return with Mikhail (and Taliyah) from inside.Currently it was her, Kaelyne, Vlad, Sgt. Louisa Petrakis (the State Cop) and Ms. Blanchard versus Missy Brandy, Sultana, Noémie Lucie, Amber Lee and Misty Dawn. With the size, or lack thereof, of herself and Kaelyne, the plan was to replace Ms. Blanchard and the Sarge with Mikhail and/or Alexander.‘I'm still busted up,' he grinned up at her.‘Oh, come on. Don't be a wimp,' she teased him, her fists on her thin, boney hips and thrust out her small chest. Her brand new white, string bikini shown on her tan-less body with the top being so conservative with the fabric it consisted of little more than two tringles kept together by their tie strings. If only she'd had more than 'A' cup sized boobs to fill them;‘Well, if you can pull me up, I'll do my best,' he conceded. Sure, she was 90 lbs. soaking wet while he was 220 lbs., but Vicky was fearless and determined to avenge the earlier pool massacre. She yanked, yanked, made some progress then went for a two hand grip on his left hand. Alexander reversing things, lightning-quick and pulled her down across his body, catching her by surprise.‘Hey!' she protested quite vocally.‘I'd like to kiss you,' Alexander requested passionately.Shock, pleasure, leaning down into Alexander; and nipping his nose.‘Ow,' he complained.‘Took you long enough,' Vicky teased him.Alexander's sudden, expressive and very public sign of affection had been the last thing she'd expected. Yes, they had exchanged sexually charged barbs and erotic innuendo for the past few days; but honestly, Vicky had felt the Samsonov she craved was beyond her. She Knew all the cheerleaders were better looking and even Kaelyne had bigger boobs. Even the 'old ladies' were disappointingly curvaceous, busty and intriguing; at least to the guys.‘Am I going to get that kiss?' Alexander brightened up.‘I don't know,' she vaulted onto his recliner so she ended up straddling his stomach just above the top of his trunks. ‘I kinda like the idea of sexually torturing you,' she added as she sat down; on him.‘Vicky!' Kaelyne reappeared out of the house with Mikhail. ‘Are you two coming?'‘Ocupado!' Vicky triumphantly pronounced. Only then, with her palms placed on Alexander's muscular pectorals, did she lean in for that kiss.‘Yippee!' Kaelyne whooped back. She truly was Vicky's best friend.‘Hey Vicky, don't break him,' Mikhail added in his own teasing.‘I make no promises,' Vicky shot back loudly and proudly. In reality, she had zero sexual experience. She had just had her first kiss; which was warm, wet and wonderful; and she was totally virgin.Vicky had never fit in, battled with ADHD most of her life and had never felt the desire to conform to any of the norms of Kingston, or Davis County. Her hair was always off-color, her only true friend was a shy, introverted, gun-loving lesbian nearly as physically under-developed as she was and, despite the oft-promise of pain, she'd never knuckled under to the bullies.Her musical tastes were unknown bands from other continents and she despised the Sports Religion, so she had expected to serve out her High School years in social exile; but the arrival of the Samsonov's had changed all that. Now she was at a Pool Party with the Cheer Squad; even though as an addendum to Kaelyne; and sexually taunting one hunk of a guy.They kissed twice more before Vicky began serpentining down his body. Lips caressed Alexander's chin, Adam's apple and sternum. Awkwardly, she reached a hand between them and between her spread legs, patting her partner's swimsuit. It took him a few seconds to figure out what Vicky was searching for.‘Umm,' he coughed, somewhat embarrassed. Vicky was turning out to be far more physically aggressive than he'd assumed. ‘It has; ah; expanded down my left leg.'‘Oh!' Vicky popped up, giving Alexander a wicked grin like some demented pixie. ‘Thanks.'She was doubly pleased. He was both not so offended as to be put off plus he was aroused. Check that; triply pleased! Alexander's Baloney Pony Was Huge! (In her inexperienced estimation). She grabbed that manly earthworm and began maneuvering it 'due north'. Soon it was rubbing beneath her covered vulva. Wiggling on it felt wonderful.Alexander's moan was almost as pleasing.‘Oh; ‘ she taunted him, ‘does someone like that?'Alexander gave two, pained nods.What 'Mad Vicky' lacked in real world expertise she compensated for with a rich, diverse and ignored 'For 18+' warning labels, internet history.She pushed herself up slowly, adding an extra twist to her wicked grin when Alexander's eyes flickered to her bikini-top covered assets. Her own quick assessment revealed that while her breasts remained small, her puffy areolas and thick, stubby nipples were flushed with blood and making indentations against her scanty covering. As she kept pushing up, Vicky couldn't help but feel victorious.She had Alexander's cock angling toward his belly button (with the tip no longer contained by his trunks) which had the added benefit of the muscle separating her labia (though equally under wraps). Damn, it felt fine! Vicky was now perpendicular to Alexander's reclining form. Her guy / victim was totally focused on her. The only thing which could make things better was to; He he he he; rub it in.Vicky raised her arms over her head, fingers interlocked then began gyrating and rocking back and forth on his aroused rod.‘Oh Yeah!' she exulted. Things only got better.After a few cycles, Alexander propped himself up with his right elbow and reached out with his left hand, placing it just below her right breast.Vicky figured he was testing her reactions. She was positively luminescent. The oldest Samsonov triplet took that as permission to move three fingers up so he could began playing with her erect nipple through her top. That felt so fine, too. The better, kept getting better.‘Hey!' Misty Dawn Sizemore protested. ‘What's that little freak doing with our guy?'Yep! Vicky's soul soared. She'd stolen a guy the cheerleaders wanted. She was doing her rendition of a barrel-riding/pole-dancing girl routine on top of him for all of those bitches to see. And the better just kept on coming.‘You like?' she resumed her taunting. Alexander nodded again. His words were unexpected.‘I really like your body, Vicky,' he expressed with such genuine openness and innocent trust it caused the tiny temptress to pause.‘You do, don't you?' she barely annunciated.‘Yeah. These nipples look absolutely delicious, you have this pert, tight little ass that wiggles every time you take a bouncing step and your smile is luminous, Vicky. Has no one has ever told you that before?'She digested his compliments and more before deciding he both was not playing her and was really, really sweet.‘No,' she added a little extra wiggle, ‘You would be the first.' Pause. ‘So, you like watching my ass?'‘Behave,' Gayle Samsonov shouted from across the pool. She and Pearl Yates were walking together down to the lawn set aside for the volleyball match.So many replies;‘But I don't want to,' Vicky faux-whined. ‘He's so yummy.'‘I wasn't talking to you, Vicky. I was warning my eldest,' Gayle laughed.‘I don't want to, Ma,' Alexander joined the protest. ‘She's so yummy!'‘Don't make me come over there,' Gayle stopped and shook her finger in their direction. Alexander flopped down and groaned. He even draped his left elbow over his eyes.‘Does this mean we stop?' Vicky get gyrating on his cock.‘I'm afraid so. Going against my Ma is dangerous. Her mean-streak is legendary among those lucky enough to be left alive,' he moaned. ‘Trust me, Vicky' he moved his arm so they were making long, in depth eye contact once more, ‘I'll get you later.'‘What about all the other girls?' she play-pouted. She was really loving this banter.‘Can I leave it at 'Mom's evil plan requires me and my Brothers to romance the Cheer Squad'; please?' Alexander frowned. Vicky wanted to know more. Accepting anything with blind obedience wasn't in her. ‘You are the one who engages me. I confess I didn't see you right away. I had some other crap on my mind, but I see you now and I'm honest about really liking what you're showing.'Pause.‘You are still going to fuck me, right?' she ground her crotch down on his cock.‘Hell yeah,' he coughed. ‘Can't you feel how hard you are making me?'‘Teehee,' Vicky giggled. ‘Just don't go all around school bragging about it,' she reiterated an earlier exchange they'd shared. ‘I'm not that kind of girl.' Total Lie.‘As I recall you are a 'write her name on the bathroom stalls' kind of girl,' he laughed.Vicky snickered.‘Don't make me have to tattoo my name on your dick,' she faux-threatened.‘Ouch,' Alexander winched. ‘Have I told you how much I adore your ass?'‘And my eyes,' she preened. She gave his cock one more vigorous circuit of stimulation then dismounted. ‘Let's go play volleyball before your Mamma has to come back up here and kick my adorable little ass.'‘How about we go down and you sit in my lap as we watch?' he offered instead. ‘I'm kind of still in a great deal of pain. Cracked ribs and all.'‘Fine,' Vicky began pulling the large man-boy up, ‘Kaelyne and I will tag in and out because, while I like that dick, I still want to kick some cheerleader ass.'‘Are you any good at volleyball,' he asked as they hobbled down to the gathering, his left arm draped over her shoulders.‘Never played before in my life. I rocked at tetherball in Kindergarten. How much harder can this be?' Vicky joked.Alexander snorted. Vicky was soaking up the jealous, angry looks being sent her way as she helped him approach. Would she pay for her usurpation later? Most likely, but the promise of retribution from those who thought they were better than her had never stopped her before; and they certainly weren't going to stop her now. This was turning out to be one of the best days of her life.Taliyah and Dominique.Taliyah found her Mother in the Carson's den running her finger over various books on the shelf while drinking a tall glass of 'something'.‘Mamma, how are you going to fix this?' she started off. Dominique looked over her shoulder then slowly turned around, a rather unhappy look on her face.‘Baby, there is no fixing what's wrong with your Daddy and I.'‘Mamma!' Taliyah shouted.

Jennifer Howard's inspiring story is one of resilience and hope in the face of immense challenges. Diagnosed with idiopathic pulmonary arterial hypertension (IPAH) in July 2019 after a long and frustrating path to answers, Jennifer faced the daunting reality of living with a chronic illness requiring continuous IV medication through a pump. Despite the overwhelming nature of her diagnosis, Jennifer discovered an inner strength she never knew she had. With a focus on living life to the fullest, she learned to navigate both the bad days and the good, embracing moments that brought her happiness and refusing to let despair take root. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com. @phacanada  

Winterpause? Pah! Schon in der zweiten Januarwoche geht es weiter mit der Fußball-Bundesliga. Da darf natürlich eine neue Folge Bohndesliga nicht fehlen! Wir starten in das neue Jahr mit der Besprechung des 16. Spieltags. Nils, Etienne, Niko und der sich in Quarantäne befindende Tobi analysieren den Spieltag in all seiner epischen Breite. Los geht es mit den beiden Top-Duellen des Spieltags. Am Samstagabend sicherte sich der FC Bayern München die Hinrundenmeisterschaft. Wie souverän der Sieg über Borussia Mönchengladbach wirklich war - darüber streiten sich die Gelehrten. Auf jeden Fall haben die Bayern einen weiteren Schritt Richtung Titel gemacht. Dabei hat sich auch Bayer Leverkusen schadlos gehalten. Die Werkself hatte das große Glück, dass Borussia Dortmund zu wenig Aspirin-Tabletten zur Hand hatte. Gleich die gesamte Abwehr fiel krankheitsbedingt aus. Die neu zusammengewürfelte Viererkette der Dortmunder schenkte sich die Tore praktisch selber ein. Wie ist der Auftritt der Schwarzgelben zu bewerten? Wir besprechen aber natürlich auch alle anderen Partien des 16. Spieltags. Nils und Etienne waren live im Millerntorstadion, als Eintracht Frankfurt mit Müh und Not den FC St. Pauli besiegte. Wie fällt ihr Fazit aus? Und was wird aus der Eintracht, sollte Omar Marmoush tatsächlich nach Manchester wechseln? Außerdem im Fokus: Union Berlins Protest über das DFB-Urteil, die Rückkehr von Xavi Simons bei RB Leipzig und der Mercedes Benz Junior Cup in Sindelfingen!

Kaitlyn Salonga shares her journey of resilience and advocacy while living with pulmonary hypertension (PH). Kaitlyn recounts her fight for personal autonomy, including a successful battle to secure surgery for her reproductive health after initial denials due to weight and health concerns. Through her triumphs, she highlights the importance of advocating for oneself in the face of medical and societal challenges. Her story is a powerful testament to embracing one's identity, breaking down stigma, and showing that life with PH can be fulfilling and bold. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com. @phacanada

Good morning from Pharma and Biotech Daily, the podcast that gives you only what's important to hear in the Pharma and Biotech world.Roche has recently finalized a new deal in China valued at up to $1 billion for an antibody-drug conjugate. However, Neumora's depression drug trial has unfortunately not yielded successful results. Additionally, Sangamo has experienced a setback by losing a partnership with Pfizer in hemophilia gene therapy. On a more positive note, Axsome has released mixed data from Alzheimer's trials but still plans to move forward with filing for FDA approval.In other recent developments, Merck's PAH drug and BMS' Opdivo injection have received regulatory greenlights. It's important to note that there are currently job opportunities available in various pharmaceutical companies for those looking to make a career move in the industry.Looking ahead to 2024, the neurobiopharma industry has been characterized as a rollercoaster of ups and downs.

CME credits: 1.00 Valid until: 20-12-2025 Claim your CME credit at https://reachmd.com/programs/cme/pulmonary-hypertension-comorbidities-with-pah-and-group-2-ph/28869/ Providers face challenges when it comes to pulmonary hypertension (PH), especially when distinguishing between PAH with comorbidities and group 2 PH. In addition, PH resulting from left heart disease may further complicate diagnosis and treatment. Hear what the experts have to say about identifying and treating these patient populations. =

Tanya Stinson shares her journey of being diagnosed with pulmonary hypertension (PH) after persistent symptoms and misdiagnoses. Her struggle highlights the difficulty of finding the right diagnosis and the emotional toll of living with a rare, chronic disease. Tanya's experience underlines the fear, mental challenges, and hope intertwined in navigating PH, inspiring others to seek support and find solace in community, showing that even in isolation, they are not alone. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com. @phacanada

Hall Skaara, a resilient PH patient and founder of the Norwegian Association for Pulmonary Hypertension, recounts his 19-year journey living with idiopathic pulmonary hypertension. He shares how he transformed the challenges of the pandemic into an innovative opportunity by helping create the Bel Air Center, a virtual global PH community space. The Bel Air Center aims to foster global connections, support, and resources for patients, caregivers, and healthcare professionals. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com. @EuropePHA 

Cynthia Neilson shares her journey as a mother raising her daughter Claire, who was diagnosed with pulmonary arterial hypertension (PAH) at a young age. Cynthia recounts the challenges she faced navigating the medical system, the emotional toll of dealing with an unexpected diagnosis, and the difficulties of balancing family life while ensuring her daughter received the best possible care. Cynthia emphasizes the value of connection, resilience, and advocacy for families dealing with rare diseases. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com. @phacanada

W ubiegłym tygodniu między Izraelem a Hezbollahem ogłoszono zawieszenie broni, które w założeniu miało przerwać trwające od kilku tygodni walki w Libanie i Izraelu. Zawieszenie broni zostało jednak obłożone warunkami, które pokazują, że obie strony pozostają w gotowości do walki. Co więcej, już po jego wprowadzeniu w życie dochodziło do wymiany ognia między walczącymi stronami. Dlaczego do tego zawieszenia broni doszło w tym momencie? Czy Izraelczycy osiągnęli deklarowane cele strategiczne i taktyczne swojej operacji na terytorium północnego sąsiada? Czy Hezbollah jest na tyle osłabiony, że libańska armia będzie w stanie kontrolować całe terytorium kraju cedrów? O tym opowiada mi dr Agnieszka Bryc z Uniwersytetu Mikołaja Kopernika w Toruniu. Odcinek zaczynamy jednak od rozmowy o sytuacji humanitarnej w Libanie i działalności Polskiej Akcji Humanitarnej. Prowadzone od kilku lat centrum GLOW świadczące przede wszystkim usługi edukacyjne dla młodszego pokolenia Libańczyków zostało uszkodzone wskutek działań wojennych. Jak to wpłynie na działalność PAH w kraju i jak PAH i inne organizacje humanitarne przygotowują się do nadchodzącej wielkimi krokami zimy? O tym mówi mi Helena Krajewska, rzeczniczka prasowa Polskiej Akcji Humanitarnej.

Natalie Roy is a double lung transplant survivor living in Canada. She was diagnosed with pulmonary arterial hypertension (PAH) in 2005 and received her transplant in 2017. . After her successful transplant seven years ago, Natalie experienced a difficult initial recovery but felt amazing once she started healing. The first two years were cautious, but she was able to achieve many milestones she never thought possible, including getting married, playing sports, and changing careers. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com. @phacanada 

Maureen Harper, a CTEPH patient from Canada, shares her journey with this rare condition. She initially thought she had an infection in her leg, but further tests revealed enlarged pulmonary arteries and multiple blood clots in her lungs. After being diagnosed with pulmonary hypertension, she underwent a complex surgery in Toronto to attempt to remove the clots. Maureen continues to work full-time as a pharmacy technician, remains active with her family and Girl Guide unit, and maintains a positive outlook, choosing to focus on the positives rather than dwell on the negatives. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com. @phacanada 

Lynette Chambers, a 9-year PAH (pulmonary arterial hypertension) patient, has also been diagnosed with pulmonary fibrosis (PF). She shares her journey, from struggling with daily activities to being admitted to the hospital with severely low oxygen levels. Lynette discusses the emotional challenges of facing a terminal illness and the difficulty of balancing work and family time. Despite the hard reality, Lynette emphasizes the importance of gratitude, making others feel better, and being the best version of oneself. She finds strength in her family, especially her grandchildren, and strives to create lasting memories and make a positive impact on those around her. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com. @phacanada

John Kingrey, MD, Director of the @integrishealth Pulmonary Hypertension (PH) Center of Oklahoma and PH patient, Nicole Fitzgerald, discuss the importance of the physician-patient relationship as it relates to participation in clinical trials including the Phase 2 TORREY Study (now the Phase 3 PROSERA Study). #GossamerBioPartner #sponsored Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com Like, Subscribe and Follow us: www.phawarepodcast.com.

In this episode of the podcast we speak to Steve Smith, a patient advocate who is living with Pulmonary Arterial Hypertension (PAH), a rare and progressive condition characterized by narrowing of the blood vessels in the heart and lungs. Steve is a college administrator and avid theater participant who uses his PAH story to connect with others, believing that open communication is key to the patient experience.   Hear More About Steve and Other PAH patients: OutnumberPAH.com   Editor's Note: Chronic conditions and rare diseases don't discriminate. Patient Worthy and our partners are interested in amplifying the voices of those from all identities and backgrounds. If you have a story to share, learn more about how your voice can help spread awareness and inspire individuals from all walks of life here: getinvolved.patientworthy.com Outnumber PAH | Living With Pulmonary Arterial Hypertension Together we can outnumber PAH. Find resources for living with pulmonary arterial hypertension and learn from the stories of people in the PAH community.  

Założycielka PAH-u o polityce migracyjnej rządu, pushbackach, ludziach m.in. z Somalii, przekraczaniu granicy, strategii UE i o swoich doświadczeniach

These educational podcasts will spotlight important research into the basic science, diagnosis, treatment, and medical management of patients with PAH based on data presented at the American College of Chest Physicians (CHEST) Annual Meeting in Boston, MA October 6-9, 2024.Launch Date: October 10 2024Release Date: October 10, 2024Expiration Date: September 30, 2025FACULTYIoana Preston, MDAssociate Professor of MedicineTufts University School of MedicineThis podcast provides accredited continuing education credits.  To receive your credit, please read the accreditation information provided at this link below prior to listening to this podcast.https://www.practicepointcme.com/CMEHome/independent-conference-coverage-from-the-american-college-of-chest-physicians-chest-annual-meeting-2024-1

These educational podcasts will spotlight important research into the basic science, diagnosis, treatment, and medical management of patients with PAH based on data presented at the American College of Chest Physicians (CHEST) Annual Meeting in Boston, MA October 6-9, 2024.Launch Date: October 10, 2024Release Date: October 10, 2024Expiration Date: September 30, 2025FACULTYIoana Preston, MDAssociate Professor of MedicineTufts University School of MedicineThis podcast provides accredited continuing education credits.  To receive your credit, please read the accreditation information provided at this link below prior to listening to this podcast.https://www.practicepointcme.com/CMEHome/independent-conference-coverage-from-the-american-college-of-chest-physicians-chest-annual-meeting-2024-1

In this episode, David Lake a retired jet pilot, discusses his experience with pulmonary arterial hypertension, initially misdiagnosed as exercise-induced asthma. Lake also manages hemophilia, COPD, and irregular heartbeats, impacting his health significantly. Despite these challenges, he remains hopeful and active in his community and church. His story is a testament to resilience and the quest for better treatment through clinical trials. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Follow us on social @phaware  Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com

Lori Myers, shares her experience living with VSD and Tetralogy of Fallot, which caused her to be born as a "blue baby" and have various health issues throughout her life. After multiple surgeries and diagnoses, she was eventually told she had pulmonary arterial hypertension (PAH). Despite the prognosis, Lori is now in her tenth year since the diagnosis. She emphasizes the importance of listening to one's own body and following medical advice. Lori finds strength in her family, particularly her grandchildren. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Follow us on social @phaware  Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com

PAH patient and Chicago-area support group leader, Sue Liss, discusses her pulmonary arterial hypertension diagnosis. Sue is involved with multiple PH related advocacy groups. Through these groups, she offers support and guidance, particularly in navigating medication funding challenges and accessing the right care, emphasizing the importance of community and shared experiences in managing this rare disease. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Follow us on social @phaware  Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com

In this episode, Dr. Scott Olitsky, the Global Center of Excellence Outreach Director for Cure HHT, discusses hereditary hemorrhagic telangiectasia (HHT), a genetic disease characterized by abnormal blood vessel development. HHT can cause bleeding in various parts of the body, with nosebleeds being the most common symptom. In some cases, HHT can lead to the development of pulmonary arterial hypertension (PAH). Medications that dilate blood vessels can worsen bleeding in HHT patients. Dr. Olitsky shares his personal connection to HHT and PAH and highlights the efforts of Cure HHT to improve diagnosis and treatment options for patients. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Follow us on social @phaware  Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com @curehht

Eric Borstein, who lives with pulmonary arterial hypertension, is walking from Los Angeles to San Diego to raise funds and awareness for the benefit of Team PHenomenal Hope.  On September 21st, 2020, while at home, he collapsed from massive right heart failure and almost died.  On September 22nd, 2024, four years after his PH diagnosis, he begin his 120+ mile walk for patients living with pulmonary hypertension.  Learn more about his journey and this amazing event at WhereIsEB.og. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Follow us on social @phaware  Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com

In this September 17, 2024 JACC issue, Dr. Zhi Jian Zhang and colleagues unveil a groundbreaking study on pulmonary arterial hypertension (PAH) that identifies plasma IgG fucosylation and glycan traits as promising prognostic markers. This research not only enhances survival predictions beyond current models but also opens intriguing possibilities for future therapeutic targets in PAH.

In this episode, Thekla McGinley, a PAH patient and advocate, shares her journey with pulmonary arterial hypertension (PAH) and the changes she has witnessed in the treatment options and education for medical professionals. She emphasizes the importance of raising awareness and ensuring that patients have access to proper treatment. Thekla also discusses her role as a support group leader and encourages patients to communicate with their doctors to advocate for themselves in order to receive the best care. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Follow us on social @phaware  Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 2620: Dr. Neal addresses concerns about air fryers potentially producing harmful compounds like acrylamide and polycyclic aromatic hydrocarbons (PAHs). While air frying may still create acrylamide, it significantly reduces PAH production compared to traditional frying methods, making it a safer alternative. Quotes to ponder: "Air fryers use this same concept but instead of surrounding a food in hot oil, it circulates hot air around the food." "When researchers compared air frying to deep frying, they found that fewer PAHs were produced by air frying." "Adding spices, like turmeric and ginger, to the marinade has also been found to reduce the production of PAHs." Episode references: Reducing PAHs in Grilled Foods: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476651/ Acrylamide and Cancer Risk: https://www.cancer.gov/about-cancer/causes-prevention/risk/diet/acrylamide-fact-sheet Learn more about your ad choices. Visit megaphone.fm/adchoices

Merriam-Webster's Word of the Day for June 17, 2024 is: apocryphal • uh-PAH-kruh-ful • adjective Something described as apocryphal is of doubtful authenticity; the term is often applied to stories or legends that are often repeated but likely not true. Apocryphal can also describe something resembling or relating to the Apocrypha, the ancient Jewish books that are not part of the Hebrew Bible but are considered canonical in Roman Catholic and Eastern Orthodox churches. In the biblical use, the word is often capitalized. // The legend of how the song was fully composed while the singer was in a deep fever state is probably apocryphal. See the entry > Examples: "There is a likely apocryphal story about how Michelangelo, upon getting criticism about David's nose being too big, climbed a ladder and pretended to chisel it." — Rita Bullwinkel, The New York Times, 27 Feb. 2024 Did you know? In biblical study, Apocrypha refers to books outside an accepted canon of scripture. In modern use, the term refers specifically to a group of ancient Jewish books that are not part of the Hebrew Bible but are considered canonical in Roman Catholic and Eastern Orthodox churches; Protestant churches follow Jewish tradition in considering these books noncanonical. Both apocrypha and apocryphal come, via Latin, from the Greek word apokrýptein, meaning "to hide (from), keep hidden (from)," which in turn comes from krýptein, "to conceal, hide." Both words entered English in the 16th century with their nonbiblical meanings, apocrypha referring to writings or statements of dubious authenticity, and apocryphal describing such things. Apocryphal is now the more common word. It most often describes an oft-repeated tale that is almost certainly not true.