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Alibaba Group's grocery retail arm Hema, also known as Freshippo, has officially exited the membership store business, shuttering all Hema X locations as it pivots toward more profitable formats amid intensifying competition in China's retail market.阿里巴巴集团旗下的杂货零售部门盒马鲜生（也称为Freshippo）已正式退出会员店业务，关闭了所有盒马X门店，因为它在中国零售市场竞争加剧的情况下转向了更有利可图的模式。Hema said that its Shanghai Senlan store, the last remaining Hema X location, will cease operations on Aug 31. The closure follows the shutdown of stores in Beijing; Suzhou and Nanjing of Jiangsu province in late July. After the Senlan store closure, Hema will no longer operate any stores under the membership model.盒马表示，其上海森兰店是盒马X最后一家门店，将于8月31日停止运营。在北京门店关闭之后，该店也随之关闭；7月下旬，江苏省苏州市和南京市。森兰门店关闭后，盒马将不再以会员模式经营任何门店。Customers holding Hema X memberships — priced at 258 yuan annually for Gold and 658 yuan for Diamond — will be eligible for refunds or can transfer benefits to other Hema formats.持有盒马X会员资格的客户（金卡年费258元，钻石卡年费658元）将有资格获得退款，或者可以将福利转移到其他盒马格式。The move signals the end of Hema's experiment with membership stores, which the company once positioned as a "second growth curve" akin to US membership giants Costco and Sam's Club.此举标志着盒马对会员店的实验结束，该公司曾将会员店定位为类似于美国会员巨头好市多和山姆会员店的“第二增长曲线”。The first Hema X opened in Shanghai in October 2020. By October 2023, the format had expanded to 10 stores across key cities.第一家盒马鲜生X于2020年10月在上海开业。到2023年10月，该模式已扩展到主要城市的10家门店。Hema management made a strategic call earlier this year to concentrate resources on Freshippo and Hema neighbor business, both of which are showing stronger growth momentum.今年早些时候，盒马管理层发出战略呼吁，将资源集中在Freshippo和盒马NB（邻居业务）上，这两家公司都显示出更强劲的增长势头。In an internal letter at the end of 2024, Hema CEO Yan Xiaolei reaffirmed confidence in the company's Hema NB format, with a goal to expand to 300 stores in fiscal year 2025.在2024年底的一封内部信中，盒马首席执行官严筱磊重申了对公司盒马NB模式的信心，目标是在2025财年将门店扩展到300家。According to Alibaba's latest annual report, Hema plans to deepen its presence in emerging cities and counties, with a focus on value-driven formats. The company's gross merchandise value surpassed 75 billion yuan in fiscal year 2025, and its adjusted earnings before interest, taxation and amortization turned positive for the first time. Freshippo now operates over 420 stores, with online orders contributing more than 60 percent of sales.根据阿里巴巴最新的年度报告，盒马计划深化其在新兴城市和县的业务，重点是价值驱动型业态。该公司2025财年的商品总价值超过750亿元，调整后的息税摊销前利润首次转为正值。Freshippo目前经营着420多家商店，在线订单占销售额的60%以上。Analysts said the collapse of Hema X highlights the challenges Chinese retailers face in replicating the US membership model.分析人士表示，盒马鲜生X的倒闭凸显了中国零售商在复制美国会员模式方面面临的挑战。"Hema X charged membership fees, but it never truly validated a mature model," said Jason Yu, general manager of CTR Market Research. "It faced pressure from both global competitors like Sam's Club and domestic players, but lacked strong differentiation in product assortment and customer experience."CTR市场研究总经理Jason Yu表示：“盒马鲜生收取会员费，但它从未真正验证过一个成熟的模式。”。“它面临着来自山姆会员店等全球竞争对手和国内企业的压力，但在产品组合和客户体验方面缺乏强大的差异化。”While Sam's Club benefits from a global supply chain and robust local procurement, most Chinese entrants lack comparable sourcing and private-label development capabilities, said Yu.余表示，虽然山姆会员店受益于全球供应链和强大的本地采购，但大多数中国进入者缺乏可比的采购和自有品牌开发能力。"Costco has started to localize its assortment, but the offering still leans heavily toward an American lifestyle that doesn't fully align with Chinese consumer habits," Yu said. "Omnichannel capabilities also remain weak — there's no front-end warehouse system to support fast delivery expectations."余说：“好市多已经开始对其产品进行本地化，但产品仍然严重倾向于与中国消费者习惯不完全一致的美国生活方式。”。“全渠道能力也仍然薄弱——没有前端仓库系统来支持快速交付的期望。”Hema's retreat from the warehouse format also reflects broader changes in Chinese consumer behavior, particularly among middle- and high-income shoppers.盒马放弃仓储模式也反映了中国消费者行为的更广泛变化，尤其是在中高收入消费者中。"High-income households still value product quality and freshness, but they've become increasingly rational," said Laura Liu, senior research analyst at market observer Mintel China. "We're seeing more of them shift toward fresh-product discount stores, which offer a better price-to-value balance."市场观察机构英敏特中国的高级研究分析师Laura Liu表示：“高收入家庭仍然重视产品质量和新鲜度，但他们已经变得越来越理性。”。“我们看到越来越多的人转向新鲜产品折扣店，这提供了更好的性价比平衡。”According to Mintel, shoppers are no longer loyal to a single retail format. Instead, they alternate between warehouse stores and discount channels depending on purchase scenarios. This crossover trend reflects a broad shift toward flexible, needs-based consumption.据英敏特称，购物者不再忠于单一的零售模式。相反，他们根据购买场景在仓库商店和折扣渠道之间交替。这种交叉趋势反映了向灵活、基于需求的消费的广泛转变。Hema is doubling down on its discount Hema NB format to capture this evolving demand.为了满足这一不断变化的需求，盒马正加倍努力推出折扣版盒马NB。Consultancy Kantar Worldpanel data show that Hema NB boosted its penetration by 1.6 percentage points in eastern China during the first quarter of 2025, outpacing growth in traditional retail formats. Overall, Freshippo's reach grew 1.3 percentage points year-on-year in the first quarter.咨询公司凯度消费者指数的数据显示，2025年第一季度，盒马NB在中国东部的渗透率提高了1.6个百分点，超过了传统零售业态的增长。总体而言，Freshippo的覆盖率在第一季度同比增长了1.3个百分点。The company has also accelerated store openings, averaging one new location every five days in 2024.该公司还加快了店铺的开业速度，2024年平均每五天就有一家新店开业。The NB format, focused on community-based stores offering aggressively priced fresh goods and snacks, has shown particular strength in town-level markets. In the first quarter, discount snack store penetration reached 18 percent, with southern and lower-tier regions seeing the fastest growth.NB模式侧重于以社区为基础的商店，提供价格高昂的新鲜商品和小吃，在城镇市场表现出了特别的优势。第一季度，折扣小吃店的渗透率达到18%，其中南部和低线地区增长最快。"Consumers are seeking more value without compromising on quality," Liu said. "Discount retailers that deliver on both fronts are well-positioned to capture share in this new retail landscape."刘说：“消费者在不牺牲质量的情况下寻求更多的价值。”。“在这两个方面都提供服务的折扣零售商处于有利地位，可以在这个新的零售格局中占据份额。”closuren.（永久地）停业/ˈkləʊʒə/warehousen.仓库、货仓/ˈweəhaʊs/

Welcome back! For this episode of the Who (Health) Cares CFMS Podcast Series, host Erin chats with Dr. Hema Gangam – the sole pediatric neurologist practicing in Windsor, Ontario. As its name suggests, pediatric neurology is a unique field where physicians diagnose and treat infants, children, and adolescents with a range of neurological conditions, including meningitis, encephalitis, hypoxic-ischemic injury, trauma, stroke, epilepsy and diseases impacting peripheral nerves and muscles. Also involved in medical education, Dr. Gangam is one of the clerkship leads in the Schulich School of Medicine. Join us as Dr. Gangam shares the marvels of pediatric neurology, insights into American and Canadian healthcare, as well as the importance of staying curious.

Der HEMA Event Traum: Was wäre, wenn Geld keine Rolle spielt? In dieser Folge erschaffen Alexander und Michael ein HEMA Event der Superlative: ein riesiger Komplex mit Turnieren, Workshops, Roßfechten, Luxusausstattung und Fechtcaddies. Alles perfekt organisiert, klimatisiert und live gestreamt. Die beiden bauen eine Welt, in der alles möglich ist. Inklusive Festivalbühne, Physio-Team und Galaabenden mit Metallica. Klingt unrealistisch? Vielleicht. Aber Ideen, die aus Träumen entstehen, sind oft die besten. Lass dich mitnehmen auf diese fantastische Reise durch das perfekte Schwertkampf-Event. Shownotes und mehr unter https://www.schwertgefluester.de/hema-event-maximal/ Schwertgeflüster ist ein Podcast von Alexander Fürgut und Michael Sprenger. Alexander ist Trainer und Mitgründer der Schwabenfedern Ulm, Autor von Der Schielhau im Detail und ficht Langschwert und Rapier. Michael ist Trainer und Mitgründer vom Fencing Club Dresden und ficht vor allem Langschwert. Dir gefällt der Podcast? Dann unterstütze uns auf auf Patreon oder lass uns eine Bewertung da. Du findest uns auch über unsere Website, bei Facebook, Instagram, YouTube sowie Spotify und überall sonst wo es Podcasts gibt. Du hast Anmerkungen zur Folge, Themenvorschläge oder möchtest als Gast in den Podcast kommen? Dann schreib uns an post@schwertgefluester.de oder komm auf den Schwertgeflüster Discord-Server.

In this episode, host Jonathan Sackier is joined by Steven Okoli, Honorary Senior Clinical Lecturer at Imperial College London. From leading the UK's first adult stem cell transplant trial for sickle cell disease to driving innovation in AI-guided transfusion strategies, Okoli shares how clinical research, patient advocacy, and equity-driven care are reshaping the landscape of haemoglobinopathies in the UK and beyond.  Timestamps  00:00: Introduction  01:58: Quickfire round  09:09: Pioneering adult stem cell transplant in sickle cell  11:41: Combining AI and genetics for blood transfusion  13:58: Systemic disparities in sickle cell  20:58: Education and advocacy  23:30: Non-cancerous blood disorders  25:18: What's next in sickle cell?  27:27: Okoli's three wishes for healthcare  

Hema Prakash is a rebel with a cause. She built her career in male-dominated boardrooms. Now she's disrupting another broken system: women's healthcare. In this powerful episode, Hema shares how her rebellious streak, global upbringing, and experience in tech and private equity converged to ignite Ponti Health—a ground-breaking, one-stop clinic for women's health care that refuses to medicalise menopause or diminish a woman's agency.Hema challenges the idea that menopause is a “condition” to be treated. For her, it's a transition—normal, natural, and deserving of slow, respectful, evidence-based care. She opens up about her own journey through perimenopause, what's missing in the Australian health system, and why women must stop putting themselves last. KEY TOPICS: · Menopause isn't a disease—and Héma's on a mission to change how it's treated· Research in women's health is underfunded and needs support.· · What it means to lead with humility, excellence, and empathy in business and health New podcast episodes drop every Monday to power your week. WHO IS HEMA PRAKASH?Hema Prakash is a dynamic entrepreneur and the co-founder of Ponti Health, Australia's first integrated clinic dedicated to women's health. With over 25 years of experience across technology, private equity, and business innovation, she brings a sharp, systems-thinking lens to healthcare. Driven by personal experience and a passion for equity, Hema is redefining menopause care—championing time, respect, and agency for women at every stage of life. FIND HEMA AT:LinkedIn https://www.linkedin.com/in/hema-prakash-503260/Explore Pont Health www.pontihealth.com.au CONNECT WITH DI & POWER OF WOMEN: LinkedIn https://www.linkedin.com/in/di-gillett-power-of-women/ Instagram https://www.instagram.com/power_of_women_podcast/ Contact https://powerofwomen.com.au/contact/ Be the first to catch inspiring interviews, empowering stories, and thought-provoking conversations. Follow, share & subscribe so you never miss an episode.Subscribe on YouTube: https://www.youtube.com/channel/UCeuAx74qUBrHxaQPEnxRpTw?sub_confirmation=1Follow on Apple Podcasts: https://podcasts.apple.com/us/podcast/power-of-women-podcast/id1735659590 CREDITS:Sound Design: Daryl Missen - www.vinilo.com.au Filming: Chocolate Studios - www.chocolatestudios.com.au DISCLAIMER: https://powerofwomen.com.au/podcast-disclaimer/ Hosted on Acast. See acast.com/privacy for more information.

In this episode, Jonathan Sackier welcomes Claudio Cerchione, haematologist and researcher at the Hematology Unit, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy. From his early interest in plasma cell disorders, Cerchione shares key insights into the evolution of multiple myeloma (MM) research, the rising role of minimal residual disease (MRD), and promising developments in monoclonal antibodies and CAR-T therapy. He also reflects on standout moments from recent European Hematology Association (EHA) Congress and American Society of Clinical Oncology (ASCO) Annual Meeting, and shares his hopes for the future of haematology.   Timestamps: 2:14: Memorable career experiences for Claudio   4:20 Biggest breakthrough in MM  5:10 Interest in plasma cell disorders  6:30 A surprising fact about multiple myeloma  7:40 Claudio's top choice for a dinner party guest  10:30 The importance of MRD in haematology  13:00 Monoclonal antibodies and CAR-T therapies  19:00 Current challenges  22:22 Claudio's key EHA and ASCO takeaways  28:30 Claudio's three magic wishes  

In this episode of Hema Now, host Jonathan Sackier is joined by Kevin Rouault-Pierre and Onima Chowdhury, to explore the biological mechanisms behind MDS, with a spotlight on SF3B1 mutations. From epigenetic stress to diagnostic strategies, this discussion bridges laboratory research and frontline care.  Timestamps 01:11 – Quickfire Round 07:11 – Haematology Misconceptions  10:56 – Understanding MDS 18:42 – Treating Myeloid Malignancies 23:20 – Epigenetic Mechanisms 28:30 – MDS Treatment Approaches 34:56 – Three Wishes 

Paul Becker (In Motu) und Michael Schüle (Sieben Schwerter) haben eine HEMA-Trainerauabildung erstellt, die 2026 in eine neue Runde startet. In dieser Folge erzählen sie, was eine professionelle Trainerausbildung aus ihrer Sicht ausmacht – von Quellenarbeit über Trainingslehre bis zu praktischen Lehrproben. Du erfährst, wie ihre Trainerausbildung aufgebaut ist, was „blended learning“ bedeutet und warum ein Fußballspiel kein gutes Aufwärmtraining ist. Wenn du selbst unterrichtest oder unterrichten willst, bekommst du hier Einblicke, Methoden und vielleicht auch etwas Inspirationen. Shownotes und mehr unter https://www.schwertgefluester.de/hema-trainerausbildung-becker-schuele/ Schwertgeflüster ist ein Podcast von Alexander Fürgut und Michael Sprenger. Alexander ist Trainer und Mitgründer der Schwabenfedern Ulm, Autor von Der Schielhau im Detail und ficht Langschwert und Rapier. Michael ist Trainer und Mitgründer vom Fencing Club Dresden und ficht vor allem Langschwert. Dir gefällt der Podcast? Dann unterstütze uns auf auf Patreon oder lass uns eine Bewertung da. Du findest uns auch über unsere Website, bei Facebook, Instagram, YouTube sowie Spotify und überall sonst wo es Podcasts gibt. Du hast Anmerkungen zur Folge, Themenvorschläge oder möchtest als Gast in den Podcast kommen? Dann schreib uns an post@schwertgefluester.de oder komm auf den Schwertgeflüster Discord-Server.

In deze podcastaflevering staan de JACK&JOZEF bij de Blankenburgtunnel (A24), die deels over de surfplas bij Vlaardingen is aangelegd. Ze bespreken de tol die geheven wordt voor deze nieuwe tunnel, die bestaat uit twee gedeeltes.Het gesprek verschuift naar het verlies van groen en poldergebied door de aanleg van infrastructuur. Er wordt gesproken over het feit dat vroeger heel Schiedam poldergebied was met veel boerderijen, en dat de grond er nog steeds zo'n 20 cm per jaar daalt. Een opmerkelijke uitzondering hierop is de locatie van een oude boerderij.De discussie over koeien in de wei versus koeien op een boot komt aan bod, refererend aan de drijvende koeienfarm in Rotterdam. JACK&JOZEF zijn het niet eens over dit concept: JOZEF vindt het verschrikkelijk dat koeien niet meer in de wei grazen omdat het geld kost, JACK benadrukt de noodzaak van efficiëntie.Daarnaast wordt de AVR (Afvalverwerking Rijnmond) besproken en de enorme hoeveelheid afval die we produceren, zelfs onbewust tijdens vakanties. Het feit dat navullen vroeger normaal was bij winkels als de Hema, en nu weer terugkomt, wordt als positief punt benoemd.Tot slot dromen JACK&JOZEF van een podcastopname in Zweden of Denemarken om een heel andere setting te creëren en het contrast met het 'platte pannenkoek'-land Nederland te ervaren. Ze besluiten om te proberen zich in te schrijven voor het Oerol festival op Terschelling in 2027, waar ze hopen de "explosie" van eenheid en saamhorigheid te ervaren die ze zich herinneren van vroeger.ENGELSTALIGE VERSIE? Check: www.JACKJOZEF.comSPONSORS- IBV Consultancy- AndreArt.nl- JPSystemsPODCAST KIJKEN & LUISTEREN- Op YouTube: YouTube.com/@podcastgemist- Op Spotify & andere streamingdiensten: PodcastGemistCONTACT & EVENTS- Vragen? Uitnodigen voor bedrijfspresentaties, conferenties, teambuilding of andere events?- Mail naar: info@PodcastGemist.nl- Actuele informatie? Bezoek: www.PodcastGemist.nl

Send me a Text Message here.How do you do that?! We're not sure.Zane Hema takes us behind the scenes of the project in Oceania. We learn about the weekly lessons, how plans have changed, who is working tirelessly, and why. Plus, he gives us a sneak peek into what's next when this project comes to an "end".Lovely to speak with our colleague Zane Hema again. Enjoy.The Interpreter's Workshop with Tim Curry is three years old in June of 2025!In the summer 2025, July and August, the Interpreter's Workshop with Tim Curry will take a break.The episodes will resume in September.Catch up on the episodes you've not listened to yet!Check me out on Instagram @interpretersworkshop.Support the showDon't forget to tell a friend or colleague! Click below! IW Community Buy Me a Coffee Get extras with a subscription! Share the PODCAST Subscribe to the Monthly Newsletter Listen & follow on many other platforms. Send me a voicemail! [TRANSCRIPTS ARE HERE] Thanks for listening. I'll see you next week.Take care now.

Send me a Text Message here.A Pacific Plea turned into a ProjectWe shine the SPOTLIGHT on fellow sign language interpreter Zane Hema and the team he works with in this episode. The light spreads as Zane illuminates the details of a grand project to bring formal training to sign language interpreters throughout Oceania. What started off as a conversation and requests for support became a blossoming 26-week program.Enjoy part 1 of the project's story through the eyes of Zane Hema.The Interpreter's Workshop with Tim Curry is three years old in June of 2025!In the summer 2025, July and August, the Interpreter's Workshop with Tim Curry will take a break.The episodes will resume in September.Catch up on the episodes you've not listened to yet!Check me out on Instagram @interpretersworkshop.Support the showDon't forget to tell a friend or colleague! Click below! IW Community Buy Me a Coffee Get extras with a subscription! Share the PODCAST Subscribe to the Monthly Newsletter Listen & follow on many other platforms. Send me a voicemail! [TRANSCRIPTS ARE HERE] Thanks for listening. I'll see you next week.Take care now.

Au milieu des montagnes du territoire de Mahagi, sur les rives du lac Albert, coule la rivière Kakoye. Ce cours d'eau sépare la chefferie de Mokombo en deux : la rive ouest, perturbée par la présence de groupes armés, et la paisible rive est, n'ayant jamais connu d'attaque de groupe armé. Aucun milicien n'ose traverser la rivière que les habitants disent magique. Conséquence : cette zone sécurisée accueille des dizaines de milliers de déplacés qui continuent d'arriver en provenance des rives du Lac Albert. De notre envoyée spéciale, En ce milieu d'après-midi, Martine revient du champ le dos courbé. Son grand âge lui a fait oublier sa date d'arrivée dans le camp de déplacé de Guenguere 3, elle qui a toujours vécu sur les rives ouest de la rivière Kakoye. « Je me suis déplacée jusqu'ici parce que mon village a été attaqué. Mon beau-frère a été tué à la machette, certains enfants de la famille aussi. Nos maisons ont été incendiées et nos biens ont été volés. Alors, je suis venue ici », se souvient-elle. Martine accuse la Codeco, une milice qui dit défendre la communauté Lendu. « Je n'avais connu un tel conflit avant. Même quand j'étais petite. Depuis, c'est très difficile. On n'a rien à manger. Si je ne travaille pas comme journalière dans le champ qui appartiennent à d'autres, comment je vais manger ? Et comment nourrir mes enfants ? », s'interroge-t-elle, désespérée.  Malgré cette extrême précarité, les huttes continuent de se construire. Les déplacés sont attirés par la sécurité qui règne dans la zone, en majorité habitée par les Alur. Cette communauté n'a formé aucun groupe armé d'autodéfense et n'est engagée ni dans le conflit communautaire qui oppose les Lendu et les Hema, ni dans les récents affrontements dans la zone littorale à proximité du lac Albert qui opposent les militaires congolais et un nouveau groupe politico-militaire, la CRP. Des affrontements que Silver a fuis il y a trois mois. « Il y a eu un combat acharné. C'était vers une heure du matin, se souvient-il. On a d'abord entendu des coups de feu. On a entendu des bombes. Nous avons pris la fuite d'abord une première fois en septembre dernier. En février, il y a eu de nouveaux affrontements entre les militaires congolais et la CRP. » Ces nouvelles arrivées entraînent des difficultés supplémentaires, déplore Justin Twambe Urumgwa le président du site de Guenguere 3. « Nous manquons de latrines, nous n'avons pas de douches et pourtant, il y a de nouvelles personnes qui arrivent et qui augmentent encore le problème. Pire encore, il n'y a pas de l'eau potable ici. Parfois, les gens se bagarrent à cause des quantités insuffisantes d'eau potable », déplore-t-il. Ces trois derniers mois, 1 880 personnes se sont ajoutées aux 8 000 déjà installées. À lire aussiManenji Mangundu, directeur d'OXFAM en RDC: «La situation humanitaire est très précaire à Goma»

Was hat ein Dreschflegel im HEMA zu suchen? Eine ganze Menge! Imko van Hulst nimmt dich mit in die faszinierende Welt einer Waffe, die einst Stadtwächter trugen, Paulus Hector Maier dokumentierte und heute überraschend leicht zu trainieren ist. Du erfährst, warum der Dreschflegel keine Bauernkeule ist, wie er sicher und günstig nachgebaut werden kann und was seine Eigenheiten im Sparring sind. Außerdem: Wie du beim weltweit ersten Dreschflegel-Turnier dabei sein kannst. Wenn du neue Perspektiven auf HEMA suchst, ist diese Folge dein Volltreffer! Shownotes und mehr https://www.schwertgefluester.de/dreschflegel-imko-van-hulst/ Schwertgeflüster ist ein Podcast von Alexander Fürgut und Michael Sprenger. Alexander ist Trainer und Mitgründer der Schwabenfedern Ulm, Autor von Der Schielhau im Detail und ficht Langschwert und Rapier. Michael ist Trainer und Mitgründer vom Fencing Club Dresden und ficht vor allem Langschwert. Dir gefällt der Podcast? Dann unterstütze uns auf auf Patreon oder lass uns eine Bewertung da. Du findest uns auch über unsere Website, bei Facebook, Instagram, YouTube sowie Spotify und überall sonst wo es Podcasts gibt. Du hast Anmerkungen zur Folge, Themenvorschläge oder möchtest als Gast in den Podcast kommen? Dann schreib uns an post@schwertgefluester.de oder komm auf den Schwertgeflüster Discord-Server.

Lydia Scarfò is a Physician Scientist at the B-cell Neoplasia Unit and an Assistant Professor at Università Vita-Salute San Raffaele, Milan, Italy.   She is involved in both clinical and pre-clinical studies, including being a co-investigator in over 20 clinical trials in haematological malignancies, including chronic lymphocytic leukaemia.  Timestamps:  0:00 – Introduction  1:14 – Quickfire questions  7:31 – Haematology inspiration  9:08 – STIL loss  11:42 – Splenic marginal zone lymphoma  13:03 – Novel targeted therapies for chronic lymphocytic leukaemia  17:35 – Covalent BTK inhibitors   19:30 – Chemo-free approach for hairy cell leukaemia  22:20 – Recent advances, challenges, and opportunities  25:58 – Three wishes 

Regeln sind gut, doch Regelbrüche sind manchmal besser! In dieser Folge decken wir zehn Regeln im HEMA auf, die Dir als Anfänger helfen, aber von erfahrenen Fechtern gezielt gebrochen werden. Warum ist das so? Und wie kannst Du lernen, diese Regeln bewusst zu durchbrechen, um taktisch im Vorteil zu sein? Alexander und Michael teilen persönliche Erfahrungen, Anekdoten und fundiertes Wissen zum telegrafieren, Angriffen im Rückwärtsgang, Overcommitment, Ringstrategien und mehr. Wenn Du tiefer verstehen willst, wann Fechtregeln sinnvoll und wann hinderlich sind, hör rein! Shownotes, Transkription und mehr unter https://www.schwertgefluester.de/10-regeln-die-erfahrene-fechter-brechen/ Schwertgeflüster ist ein Podcast von Alexander Fürgut und Michael Sprenger. Alexander ist Trainer und Mitgründer der Schwabenfedern Ulm, Autor von Der Schielhau im Detail und ficht Langschwert und Rapier. Michael ist Trainer und Mitgründer vom Fencing Club Dresden und ficht vor allem Langschwert. Dir gefällt der Podcast? Dann unterstütze uns auf auf Patreon oder lass uns eine Bewertung da. Du findest uns auch über unsere Website, bei Facebook, Instagram, YouTube sowie Spotify und überall sonst wo es Podcasts gibt. Du hast Anmerkungen zur Folge, Themenvorschläge oder möchtest als Gast in den Podcast kommen? Dann schreib uns an post@schwertgefluester.de oder komm auf den Schwertgeflüster Discord-Server.

Rafael Fonseca is a distinguished Haematologist at Mayo Clinic, specialising in multiple myeloma and related plasma cell disorders. He earned his medical degree at Universidad Anáhuac in Mexico, and went on to complete his residency in Internal Medicine at the University of Miami, Florida, USA followed by a Hematology and Oncology fellowship at Mayo Clinic in Rochester, Minnesota, USA.     Timestamps  01:44 – Quickfire questions  07:25 – CAR-T cell therapy  10:48 – Anti-CD38 antibodies  13:31 – Minimal residual disease  14:30 – Bispecific antibodies  15:31 – Antibody-drug conjugates  19:04 – ASCO 2025  21:24 – Genetic discoveries  26:28 – Fonseca's three wishes 

De Russische hackersgroep 'Laundry Bear' zat achter een grote cyberaanval waar onder meer de politie vorig jaar september slachtoffer van was. Wie deze Russische groep is, hoor je in deze uitzending van The Daily Move. Ander nieuws uit The Daily Move: Het plan van Trump voor de bouw van nieuwe AI-datacenters komt maar niet van de grond. En het is nog maar de vraag of het er ooit komt. De jaarcijfers van HEMA kwamen vandaag en die lieten twee dingen zien: de omzet stéég met 2 procent, maar de nettowinst daalde juist. Of het nou goede of slechte cijfers zijn, bespreken we met Kitty Koelemeijer, hoogleraar marketing en retailing aan de Nyenrode Business Universiteit. ING bood vandaag z'n excuses aan vanwege discriminatie. Maar hoe bied je als bedrijf je oprechte excuses aan? See omnystudio.com/listener for privacy information.

In this episode of Hema Now, host Jonathan Sackier is joined by Paolo Gallipoli, Clinical Reader at the Centre for Haemato-Oncology at Barts Cancer Institute, to break down the biology, onset, and treatment of myeloid leukaemias. They detail common misconceptions about myeloid leukaemias, explain the differences between chronic myeloid leukaemia and acute myeloid leukaemia, and discuss Gallipoli's own research in the field, with a view towards future developments.  Timestamps  01:34 – Quickfire questions  06:55 – Potential careers  08:43 – Common misconceptions  11:34 – Best advice received  13:43 – Adaptive metabolic changes  16:45 – Chronic myeloid leukaemia vs acute myeloid leukaemia  19:20 – Recent publication  22:55 – Clonal hematopoiesis    27:13 – Treatment obstacles  29:18 – Future developments  31:01 – Gallipoli's three wishes 

In this episode of Hema Now, Diu Nguyen joins Jonathan Sackier to discuss breakthroughs in acute myeloid leukaemia (AML) research. From RNA-binding proteins to the future of stem cell-targeted therapies, Nguyen shares the translational goals of her lab and what's on the horizon in AML diagnosis and treatment.    Timestamps:  01:20 – Quickfire Insights  03:32 – AML Breakthroughs  04:47 – Leukaemia Surprise  06:42 – Alternate Pathways  07:54 – RNA Differences  12:08 – Diagnostics Future  14:03 – RBMX Spotlight  20:21 – Targeted Therapies  27:07 – Treatment Barriers  31:32 – Three Wishes 

In deze aflevering spreek ik met illustrator Roeqiya Fris (@Roeqie). Roeqiya creëert kleurrijke, intuïtieve illustraties vol symboliek waarin haar Egyptische achtergrond, vrouwelijkheid en liefde voor natuur duidelijk zichtbaar zijn. Haar werk trok razendsnel internationale aandacht via Instagram, en sindsdien werkte ze voor grote merken als HEMA, Flow Magazine, Penguin Random House en vele mode- en puzzelmerken. Roeqiya vertelt openhartig over haar pad naar succes, de uitdagingen van ondernemen op je eigen voorwaarden, haar creatieve proces en hoe zij zichzelf blijft uitdagen en vernieuwen.

In this episode of Hema Now, Jonathan Sackier is joined by John Riches, Clinical Reader in Cancer Immunometabolism at the Barts Cancer Institute and Honorary Consultant Haemato-oncologist. They explore how metabolic shifts drive lymphoma progression, the potential of immunotherapy, and what the future holds for treating lymphoid malignancies.  Timestamps:      00:00 – Introduction  01:46 – Riches' journey into haematology  03:42 – What is T cell exhaustion?  07:06 – The key role of metabolism in lymphoma  09:33 - Richter's syndrome  13:17 – Breakthroughs in immunotherapy  20:27 – The challenges of translational research  25:39 – B cells in autoimmune diseases  28:16 – The potential of breath biopsy  32:58 – Riches' three wishes for healthcare 

This week, Jonathan is joined by Shaji Kumar, an expert in hematology and oncology, particularly multiple myeloma, who has made significant contributions to both clinical and translational science. Timestamps:  (00:00) – Introduction   (02:23) – Drug combinations and myeloma biology  (08:34) – Treating newly diagnosed multiple myeloma  (17:24) – Quadruplet regimens   (23:09) – Clinical trials for plasma cell malignancies  (28:04) – The bone marrow microenvironment in multiple myeloma  (30:29) – “Blind men and an elephant”  (33:58) – Kumar's three wishes for healthcare   

"The sound piece was inspired by the Mexico City mariachi street march, I was inspired by the poly rhythmic patterns and the instruments I was hearing over the street sounds in the recording. I enjoyed how the sound kept changing and gave the impression of moving through a street or passage with sound. In my composition I imagined myself as part of the procession whilst trying to create an individual experience and thus the sub-theme: Hema, which is a Tswana word that translate to breathe and comments how collective happenings and events can be a moment of exhalation and clarity for another as it was listening to the original sound.  "I used voice together with virtual and actual instruments to create a multi layered landscape. I used voice over recorded drums,chatter, and a bamboo flute alongside virtual instruments such as brass and atmospheric keys. The sound piece starts with trumpets sounded from the march and into a contemplative soundscape lead by the flute and mouth sounds."  Mexico City mariachis reimagined by Boitumelo Motau. ——————— This sound is part of the Sonic Heritage project, exploring the sounds of the world's most famous sights. Find out more and explore the whole project: https://www.citiesandmemory.com/heritage

Timestamps:      00:00- Introduction  00:41- Health benefits of yoga and mindfulness   02:34- The potential of AI in hematology  04:23- Transfusion dependence in myelodysplastic syndromes  08:13- The fascinating field of apheresis  10:56- How to provide high-quality, affordable healthcare?  15:44- Regulatory T cells in hematologic malignancies  19:55- CAR T clinical trials: regulatory insights  22:57- EBMT initiatives  30:06- Latest breakthroughs in amyloidosis   34:50- Reducing patient fear through education 

Twenty-three women from seven regions in Guyana completed the NSI Caricom MasterClass, a three-day program focusing on eco-friendly nail techniques. Led by Regional NSI Educator Lexann McPhoy and Global Educators Darlene Tewitz and Katia Da Silva, participants gained certification in using HEMA-free NSI products. NSI Nails Guyana City: Georgetown Address: 57 Hadfield Street Website: https://lexannnsi.com/nsi-guyana Email: pr@lexannnsi.com

In this insightful episode of Healthy Mind, Healthy Life, host Avik Chakraborty sits down with Dr. Hema Murty to discuss pain solutions for women over 50. Many women are told that pain is an inevitable part of aging—but is that really true? Dr. Murty shares her holistic approach to pain management, emphasizing the mind-body connection, stress management, and self-care. She breaks down how pain isn't just physical—it's a combination of movement, mindset, and emotional well-being. Through her 20+ years of experience, she has helped women reclaim their mobility, reduce stress, and take charge of their health. Tune in for actionable insights on how to stay active and live pain-free at any age!   About the Guest   Dr. Hema Murty is an author, advanced yoga instructor, certified personal trainer, and nutrition coach with expertise in East Indian philosophy. With over two decades of experience, she specializes in helping women over 50 break free from chronic pain and rediscover strength, flexibility, and joy in movement.

Beau Glitschka joins us in remote bathrooms to discuss the sweat he gets into during HEMA. That said, we also lean what HEMA is, talk taxes, and Beau shares his thoughts on all things bathroom. -- Follow Beau -- Connect: www.privy-cast.com Social and Contact Links: drum.io/privycast Follow Hunter -- To a Freer World and Cleaner Water: $1 Donated for every rating and review. Wounded Warrior Project Living Water International -- Music:  Intro and Outro: "Barroom Ballet" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License http://creativecommons.org/licenses/by/4.0/ -- Privy is proud to be hosted by Podbean. Looking to start a podcast? Learn more at: https://www.podbean.com/Privycast

This week, Jonathan is joined by Xavier Leleu, world-renowned expert in multiple myeloma, Waldenström's macroglobulinemia, and amyloidosis. The pair discuss groundbreaking advances in clinical trials and the future of myeloma immunotherapy.   Timestamps:  (00:00)-Introduction  (00:59)-Clinical trial breakthroughs in transplant-ineligible myeloma  (03:38)-Minimal residual disease: a key endpoint   (05:21)-Rethinking therapeutic strategies in myeloma   (10:58)-Challenges in late-line myeloma therapies   (13:54)-T-cell-engaging bispecific antibodies   (17:41)-Waldenström's macroglobulinemia and amyloidosis  (21:50)-What's next in multiple myeloma treatment?  (24:43)-Xavier's three wishes for healthcare   

You can download your FREE report on how you can avoid financial mistakes as a dentist using the link just here >>>  dentistswhoinvest.com/podcastreport———————————————————————What if your dental practice could run itself while you work just one day a week? Dr. Hema Dhingra shares how she transformed from an associate to a thriving practice owner, tripling turnover and building a self-sustaining business all while balancing motherhood.She reveals the mindset shifts, leadership strategies, and culture-building techniques that helped her scale from three dentists to a multi-specialist team proving that practice ownership doesn't have to mean burnout.Thinking of buying a practice? This episode is packed with insights to help you make it happen!———————————————————————Disclaimer: All content on this channel is for education purposes only and does not constitute an investment recommendation or individual financial advice. For that, you should speak to a regulated, independent professional. The value of investments and the income from them can go down as well as up, so you may get back less than you invest. The views expressed on this channel may no longer be current. The information provided is not a personal recommendation for any particular investment. Tax treatment depends on individual circumstances and all tax rules may change in the future. If you are unsure about the suitability of an investment, you should speak to a regulated, independent professional.Send us a text

Let us know how you enjoyed this episode!Are you struggling to navigate the cringey topic of sex education with your kids? I have known Kathleen for years and I am so excited I got to finally record an episode with her. Kathleen is a sex education advisor for parents and in this episode, she shared invaluable insights on making these tough conversations easier. From early discussions about body parts to addressing myths, masturbation, and even porn literacy, this episode covers it all. Kathleen debunks common misconceptions and provides a step-by-step guide to foster a healthy dialogue between parents and children, focusing on age-appropriate information. Tune in to learn the recommended age ranges for these essential talks and ways to empower your children with accurate knowledge. Connect with Kathleen:Website: www.kathleenhema.comTop Talks Guide for Parents: https://kathleenhema.com/digital-downloadsFree Sex Talks Starter Pack for parents of kids aged 4-15: https://kathleenhema.com/free-guideThank you for listening!If you resonated with this episode and you're ready to break the cycles you've noticed in your marriage, reach out by booking a clarity call to become a client! https://michellepurta.as.me/clarityConnect and send a message letting me know what you took away from this episode: @michellepurtacoaching and follow me on threads @michellepurtacoaching!If you would like to support this show, please rate and review the show, and share it with people you know would love this show too!Additional Resources:Ready to put a stop to the arguments in your marriage?  Watch this free masterclass - The #1 Conversation Married Couples Need To Have (But Aren't)Want to handle conflict with more confidence? Download this free workbook!Wanna stop feeling like roommates and bring back the romance and excitement in your marriage? Learn more about how coaching here!

This week, Jonathan is joined by Eytan Stein, Chief of the Leukaemia Service and an Attending Physician at Memorial Sloan Kettering Cancer Center, New York, USA.  Timestamps:      (00:00)-Introduction  (01:05)-The current landscape of treatments  (02:26)-The promise and peril of differentiation therapy  (05:55)-Highlighting the most impactful clinical trials  (08:38)-Epigenetics and the future of targeted therapies  (10:40)-The BEAT AML master clinical trial  (12:57)-The latest research into IDH inhibitors  (16:10)-Therapies for splicing factor mutations  (19:29)-Reducing patient fear with education   (22:46)-Stein's three wishes for healthcare   

A note about the work “The Ant and the Grasshopper” from Hema Padhu for the Michigan Quarterly Review's Winter 2025 Issue: One of my favorite short stories is Trevor William's A Choice of Butchers, and to some extent, his story inspired me to write this one. I'm drawn to children's perspectives. I think adults don't give them enough credit for what they see and understand. A child's perspective, however, is limited, so I wanted to take this story into Divya's adulthood to give the narrator some retrospective understanding of her mother's decision. I love short stories that work with time. It can give a story an expansive, novelistic feel. I wanted to play with time here to trace the life trajectory of these two very different women. The struggles of one generation inevitably echo in the choices made by the next. In both Divya and Selvi's lives, some choices were made consciously, some they had no control over, but throughout the story, both stay true to their nature. I did not want a big epiphany ending. Life rarely works that way.

Huko Gaza Kaskazini, kwenye eneo la wapalestina linalokaliwa na Israeli, wanafamilia zilizofurushwa makwao kutokana na vita kati ya Israeli na wanamgambo wa Hamas wanavumilia msimu wa baridi kali katika makazi ya muda ya mahema yanayopigwa na upepo na mvua usiku na mchana, limesema shirika la Umoja wa Mataifa la kuhudumia Watoto UNICEF. Nyumba zao zimeharibika na kuacha watoto kuishi katika mazingira mabaya. Ni sauti ya watoto wakitembea katikati ya mahema ya muda kwenye vichochoro vilivvyojubikwa na matope, hapa Gaza Kaskazini, huku wakijaribu kukwepa madimbwi ya maji yaliyosababishwa na mvua kubwa.Kupitia video iliyoandaliwa na UNICEF, Shahd Omar, msichana mwenye umri wa miaka kumi na saba, anaonekana amembeba nduguye, wengine wanaonekana wamekujikunyata kutokana na baridi. Shahd sasa akiwa amesimama nje hema lao anaelezea jinsi nyumba zao zilivyoharibiwa.“Tunavumilia hali ngumu sana,mvua kubwa, baridi, na upepo mkali, maisha ni magumu sana. Nyumba yetu ilivyoshambuliwa na kubomoka tulijitoa kwenye vifusi. Nyumba yetu imeharibika, hatuna samani, hakuna vituo vya kujikinga, wala mahali pa kukaa ili kupata joto. Maisha ni magumu. Hema letu lilikuwa karibu kupeperuka kwa sababu ya upepo mkali.”Kwingineko hapa, watoto wanaonekana wakicheza kwenye matope nje ya mahema zao huku maji yakitiririka kama mto. Layla Abu Asi ni mama wa watoto watatu, mwenye umri wa miaka 27 anasema,“Baridi hii ni kali mno, haiwezi kuvumilika ,upepo huu mkali umeleta madhara makubwa kwenye hema letu. Tangu asubuhi, maji ya mvua yamejaa kwenye hema letu, kila kitu kilichomo ndani kikilowa na kujaa maji. Watoto wangu wametota kwa maji ya mvua. Hii ni hali mbaya zaidi ambayo tumewahi kukumbana nayo.”UNICEF na wadau wanafanya kila wawezalo kuwasaidia wakazi wa Gaza.

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This week, Jonathan is joined by Fredrik Schjesvold, Head of the Oslo Myeloma Center Oslo University Hospital, Head of the Norwegian myeloma association, and President of the Nordic Myeloma Study Group.   Timestamps:      (00:00)-Introduction   (04:24)-Research into melflufen  (07:14)- Ide-cel CAR T-cell therapy  (09:40)-Predictors of overall survival  (12:15)-Innovative therapies for refractory myeloma  (14:04)-Bi-specific antibodies  (16:42)-Global guidelines for myeloma  (22:00)-Healthcare economics  (25:45)-Antibody-based therapies  (29:38)- Latest research into amyloidosis  (34:23)-Recent breakthroughs in myeloma  (38:06)-Fredrik's three wishes for healthcare     

Hema Natesan is the Founder & CEO at My Little Moppet, a Shopify store that's India's number 1 destination for healthy kids food. With over 7,000 verified 5 star reviews, their core marketing strategy of Community is clearly working! Founded in 2014 they now do $2 million US dollar in sales each year. Hit PLAY to hear: How Hema grew her blog into a $2M eCommerce brand The secret sauce behind My Little Moppet's WhatsApp community Why transparency wins in a competitive eCommerce market How to reduce ad spend without losing revenue The must-know tips for cracking India's eCommerce scene. Key timestamps to dive straight in: [03:19] Blogging journey: from doctor to food blogger. [07:51] Blogging: a community resource platform. [11:50] Hiring Strategy: mold fresh talent. [14:43] eCommerce success in India: key factors. [17:28] Cutting ad spend, boosting sales. [18:45] Listen to Hema's Top Tips! Full episode notes here: https://ecmp.info/529Download our ebook >> https://ecmp.info/ebook "500 Top Tips to Make Your eCommerce Business More Profitable" Download our new ebook... https://ecmp.info/ebook 500 Tips to Increase Your ProfitsGet all the links and resources we mention & join our email list at https://ecmp.infoLove the show? Chloe would love your feedback - leave a review here: https://ecmp.info/review or reply to the episode Q&A on Spotify.Interested in being a Sponsor? go here: https://ecmp.info/sponsor This podcast uses the following third-party services for analysis: Spotify Ad Analytics - https://www.spotify.com/us/legal/ad-analytics-privacy-policy/

माफ करणं अवघड का आहे? Forgiveness आणि forgetfulness एकच आहे का? माफ करायचं म्हणजे दरवेळी let go करायचं का? माफी मागण्यात कमीपणा का वाटतो? माफीचे टप्पे काय असू शकतात? माफी मागण्याची वेळ असते का? क्षमा केल्यानंतर काय होतं? स्वतःला माफ करणं का महत्वाचं आहे आणि ते शक्य आहे का? या सगळ्यावर आपण हेमा होनवाड (शिक्षिका, Educationist) यांच्याशी खुसपुस केली आहे. Why is forgiveness so difficult? Are forgiveness and forgetfulness the same? Does forgiving always mean letting go? Why does apologizing sometimes feel like a loss of dignity? What are the different stages of forgiveness? Is there a right time to apologize? What happens after we forgive? And most importantly, why is self-forgiveness essential, and is it truly possible? We explored all these questions in a heartfelt conversation with Hema Honawad (Teacher and educationist). Stay tuned for an insightful discussion! आणि मित्रांनो आपलं Merch घेण्यासाठी लगेच click करा! Amuktamuk.swiftindi.com Disclaimer: व्हिडिओमध्ये किंवा आमच्या कोणत्याही चॅनेलवर पॅनलिस्ट/अतिथी/होस्टद्वारे सांगण्यात आलेली कोणतीही माहिती केवळ general information साठी आहे. पॉडकास्ट दरम्यान किंवा त्यासंबंधात व्यक्त केलेली कोणतीही मते निर्माते/कंपनी/चॅनल किंवा त्यांच्या कोणत्याही कर्मचाऱ्यांची मते/अभिव्यक्ती/विचार दर्शवत नाहीत. अतिथींनी केलेली विधाने सद्भावनेने आणि चांगल्या हेतूने केलेली आहेत ती विश्वास ठेवण्याजोगी आहेत किंवा ती सत्य आणि वस्तुस्थितीनुसार सत्य मानण्याचे कारण आहे. चॅनलने सादर केलेला सध्याचा व्हिडिओ केवळ माहिती आणि मनोरंजनाच्या उद्देशाने आहे आणि चॅनल त्याची अचूकता आणि वैधता यासाठी कोणतीही जबाबदारी घेत नाही. अतिथींनी किंवा पॉडकास्ट दरम्यान व्यक्त केलेली कोणतीही माहिती किंवा विचार व्यक्ती/कास्ट/समुदाय/वंश/धर्म यांच्या भावना दुखावण्याचा किंवा कोणत्याही संस्था/राजकीय पक्ष/राजकारणी/नेत्याचा, जिवंत किंवा मृत यांचा अपमान करण्याचा हेतू नाही.. Guests: Hema Honawad (Teacher and educationist). Host: Omkar Jadhav. Creative Producer: Shardul Kadam. Editors: Madhuwanti Vaidya, Rohit Landge. Edit Assistant: Ranjit Kasar. Content Manager: Sohan Mane. Social Media Manager: Sonali Gokhale. Legal Advisor: Savani Vaze. Business Development Executive: Sai Kher. Intern: Saiee Katkar, Mrunal Arve. Connect with us: Twitter: https://twitter.com/amuk_tamuk Instagram: https://www.instagram.com/amuktamuk/ Facebook: https://www.facebook.com/amuktamukpodcasts Spotify: Khuspus #AmukTamuk #MarathiPodcasts #khuspus

This week, Jonathan is joined by Anna Sureda, Head of the Clinical Hematology Department at Institut Català d'Oncologia - Hospital Duran i Reynals, Barcelona, Spain, and President of the European Society for Blood and Marrow Transplantation (EBMT) Association, to discuss the latest in lymphoma therapies and stem cell transplantation. Timestamps:     (00:00)-Introduction  (01:48)-Memorable travels  (07:44)-Sureda's journey into hematology   (12:40)-Breakthroughs in lymphoma treatment   (17:54)-Advances in stem cell transplantation   (20:26)-EBMT initiatives  (29:17)-Allogeneic transplantation for T cell lymphomas  (34:32)-Challenges in treatment accessibility   (41:35)-How can we ensure health equity?  (46:00)-Advice to young hematologists   (47:40)-Sureda's three wishes for healthcare 

Hema Raghavan is co-founder of Kumo, a company that makes graph neural networks accessible to enterprises by connecting to their relational data stored in Snowflake and Databricks. Hema talks about how running GNNs on GPUs has led to breakthroughs in performance as well as the query language Kumo developed to help companies predict future data points. Although approachable for non-technical users, the product provides full control for data scientists who use Kumo to automate time-consuming feature engineering pipelines. Mentioned in this episode: Graph Neural Networks: Learning mechanism for data in graph format, the basis of the Kumo product Graph RAG: Popular extension of retrieval-augmented generation using GNNs LiGNN: Graph Neural Networks at LinkedIn paper  KDD: Knowledge Discovery and Data Mining Conference Hosted by: Konstantine Buhler and Sonya Huang, Sequoia Capital

This week, Jonathan is joined by Marc Hoffman, Associate Professor in Hematologic Malignancies and Cellular Therapeutics at the University of Kansas Medical Center, to discuss novel therapies for B-cell malignancies and current challenges in hemato-oncology.   Timestamps:     (00:00)-Introduction  (03:24)-What is molecular biophysics?  (07:01)-Marc's journey into hemato-oncology  (09:36)-Advice to young doctors  (13:08)-Treatment advances in diffuse large B-cell lymphoma   (19:11)-BRUIN study: pirtobrutinib for B-cell malignancies   (26:15)-Challenges in CAR-T therapy implementation  (31:31)-A pharmaceutical perspective   (38:10)-Regulatory insights into clinical trials  (40:58)-New horizons in hemato-oncology  (44:26)-Marc's three wishes for healthcare 

This week, Jonathan is joined by Dr Shahram Kordasti, Associate Professor in Applied Cancer Immunopathology at King's College London, UK. In this episode, Dr Kordasti discusses the immunobiology of Myelodysplastic syndrome and Aplastic anaemia, the role of CD4+ T cells in myeloid malignancies, and how cutting-edge computational tools are enhancing treatment strategies.   Timestamps:  (00:00)-Introduction  (01:23)-Hodgkin's lymphoma origin   (04:21)- Immunobiology of diseases  (08:55)-Plasticity of T cells   (13:42)-Computational biology and multiomics for patient stratification  (21:00)-Standardising immune monitoring  (25:41)- Pretreatment with systemic agents  (27:55)- Myeloproliferative neoplasms  (31:48)-Synthetic data generation   (36:22)-Exciting developments on the horizon   (39:16)-Three wishes for healthcare  

Culture isn't just a vibe—it's a choice! In today's Predictive Index replay, Hema Crockett, co-founder of Gig Talent, joins Matt Poepsel to break down what it really takes to build a culture that works. Spoiler alert: it's about values, not perks. Hema shares her secrets on getting everyone involved in shaping culture, why high performance goes way beyond numbers, and how leaders can make or break a team's vibe. Tune in for fresh insights and real talk on creating a workplace people actually want to be a part of!

This episode focuses on Arnold Clark Rewards… the new loyalty programme from Arnold Clark. With Emily Walker, the Head of Media & Brand Marketing for Arnold Clark. And Hema Kukadia, a Partnerships Account Director at Mando-Connect. Today we will be learning about their favourite loyalty programmes, how Arnold Clark Rewards is delivering for customers and the business and all about their plans for the future.Hosted by Charlie HillsShow Notes :1.Emily Walker2.Hema Kukadia 3. Arnold Clark Rewards4.European Loyalty Whitepaper5.Mando-Connect6.YouGov

This week, Jonathan is joined by David Gómez-Almaguer, Head of the Haematology Service at University Hospital Monterrey, Mexico. They discuss advancements in stem cell transplantation, the state of haematology in Latin America, and the future of innovative therapies in the field.  Timestamps:     (00:00) – Introduction  (01:16) – David's hobby: playing in a rock band  (03:06) – How David began in haematology  (04:35) – Stem cell transplantation and therapies  (06:27) – CAR-T cells  (07:35) – New treatments for aplastic anaemia, chronic lymphocytic leukaemia, and myelodysplastic syndrome   (10:54) – Recent clinical trial for Philadelphia positive acute lymphoblastic leukaemia  (12:55) – The current status of cord blood donation  (16:08) – Impact of race and ethnicity on outcomes after umbilical cord transplantation  (16:58) – The effect of resource and budget constraints on healthcare quality  (23:20) –  Novel developments in diagnosis and treatments in haematology  (27:12) –  David's three wishes for healthcare    

After healing from a painful fall, Hema Kundargi learned the value of walking meditation.

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For transcriptions and more detailed shownotes, please go to: https://swordschool.shop/blogs/podcast/episode-198-safety-testing-hema-with-jamie-maciver To support the show, come join the Patrons at  https://www.patreon.com/theswordguy Jamie MacIver is a historical martial arts instructor who co-founded the London Historical Fencing Club in 2016, which has grown to over 120 members and now has his own permanent training space. We start our conversation with Vadi, and why Jamie prefers Vadi to Fiore. We have a discussion about guards and whether Vadi is more defensive than Fiore. You can find updates on Jamie's translation of Vadi's The Art of Swordfighting on his website, here: https://historicalfencingresearch.com/projects/translation-vadi/ Next, Jamie explains about taking the plunge into getting his club its own permanent space. The London Historical Fencing club is one of only around three in the UK that has a permanent home, so we hear how it was possible post-pandemic, and how they manage the classes to make it financially viable. Jamie also explains about the steps they have taken to ensure diversity within the club. Having been involved in running lots of tournaments, Jamie found he was having to make decisions on what HEMA kit is safe enough with nothing much to back up those decisions. So he set up the Historical Research Company Ltd to research historical martial arts safety, starting with research into sword tips. What is the difference between having a tip and no tip on your rapier? And which tips are the safest? Do different tips affect how likely it is for sword to glance off a mask or to stick to a mask, causing concussion and other injuries? You can find out more about the project and its conclusions here: https://historicalfencingresearch.com/projects/safety-tips/ And there's a video here: https://youtu.be/wAZgMmIak-Y You can support Historical Fencing Research here: https://historicalfencingresearch.com/support-our-work/

For transcriptions and more detailed shownotes, please go to: https://swordschool.shop/blogs/podcast/episode-196-theory-and-practice-and-pole-dancing  To support the show, come join the Patrons at  https://www.patreon.com/theswordguy In today's show I'm sharing some excerpts from the audiobook of The Theory and Practice of Historical Martial Arts. You can find the book in both audio, print, and ebook formats at https://swordschool.shop/products/the-theory-and-practice-of-historical-martial-arts-audiobook I'm also revisiting my interview with the audiobook's narrator, Kelley Costigan. Here are the notes for the episode: Kelley Costigan is an actor, director, pole dancer, fencer, performance combatant, adventurer and pirate, currently living in Stratford-upon-Avon, UK, home of William Shakespeare. Listen to our conversation to discover the Shakespeare connection that inspired me to ask Kelley to narrate my audiobook, The Theory and Practice of Historical Martial Arts. (It's out now: you can probably find it in your audiobook app of choice, or get it directly from me here: https://swordschool.shop/products/the-theory-and-practice-of-historical-martial-arts-audiobook.) As a child, Kelley was told that fencing was “not something that girls do”, but she has since made up for it after taking up HEMA in her 40s. We also talk about competitive fencing, competitive pole dancing (yes, that's a thing,) not being a Russian spy, and what Kelley would do with a million pounds. In case you've never seen someone pole dancing with a sword before, here's one of Kelley's performances: https://vimeo.com/221580829 To find out more about Kelley, her website is www.kelleycostigan.com.

Sword influencers abound on YouTube. Those who specialize in the historic European martial arts, or HEMA, have gained legions of fans showcasing the fantastic, bladed techniques of yore. But talk of parries and pommels has recently given way to bigotry. Endless Thread's Ben Brock Johnson speaks with co-host Amory Sivertson about one valiant influencer fighting back. ***** Credits: This episode was produced by Ben Brock Johnson and Dean Russell. Mix and sound design by Emily Jankowski. The hosts are Amory Sivertson and Ben Brock Johnson.