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Once I got my diagnosis of invasive ductal carcinoma, I was immensely scared of dying. I was shocked and sad about the diagnosis. I was sure I needed a double mastectomy, because I never wanted to get diagnosed with another breast cancer. My doctors did not recommend a double mastectomy. I only had the left mastectomy. I started tamoxifen a few weeks after surgery. Now, two years since the diagnosis, I am confident that I will not be diagnosed with a cancer in my remaining (right) breast. There are two strategies in place for me at this time that lower my fear of another breast cancer developing. First, I now have a breast cancer screening plan that was developed with my oncologist, to best screen my dense breast tissue. This involves MRI and contrast-enhanced mammography. Secondly, and equally as important, I am taking tamoxifen. Tamoxifen is prescribed as my anti-estrogen or hormonal therapy, to reduce the risk of that prior breast cancer showing up somewhere else in my body. At the same time, tamoxifen has an effect on the tissue in my right breast, to halt the development of cancer. The way tamoxifen benefits my breast tissue will provide reduced risk of cancer in that breast for several years. If you'd like to be the first to receive updates and exclusive content from the upcoming Breast Cancer Life newsletter, please email me at connect@breastcancerlife.org. I'd love to have you on the list! LET'S CONNECT: connect@breastcancerlife.org Follow us on Pinterest
Because of breast cancer, fear of cancer recurrence is a permanent part of my life. I continue taking tamoxifen to reduce my risk of the cancer coming back. In this episode I share my thoughts on the good quality of life I have while taking tamoxifen. I value my strong body and theimited side-effects I have now. I also value a life with the lowest possible risk of breast cancer recurrence. I look forward to discussing what it might mean to switch to an aromatase inhibitor, in terms of further lowering the risk of recurrence and potentially experiencing more serious side-effects, with my oncologist On more than one occasion, the oncologist has brought up endocrine therapy and the possibility of switching from tamoxifen to an aromatase inhibitor “in the future”. Even my breast surgeon provided a quick plug for the lower risk of recurrence associated with taking aromatase inhibitors, compared to tamoxifen, without highlighting any of the aromatase inhibitor side-effects. Determining what might be the best endocrine therapy for me to prevent recurrence is not going to be easy. So far, neither doctor has done a deep dive into the different side-effects among the two drugs or what a change might do to overall health and quality of life. Thank you for listening to my story! If you'd like to be the first to receive updates and exclusive content from the upcoming Breast Cancer Life newsletter, please email me at connect@breastcancerlife.org. I'd love to have you on the list! LET'S CONNECT: connect@breastcancerlife.org Follow us on Pinterest
In this episode of the Better Than Before Breast Cancer podcast, we're diving into how common post-treatment medications—like Tamoxifen, Aromatase Inhibitors (Letrozole, Anastrozole, Exemestane), Herceptin, Fulvestrant, and Bisphosphonates (like Fosamax and Reclast)—can deplete critical nutrients your body needs to feel good and stay strong. Have you ever wondered if the medications you're taking after breast cancer treatment could be affecting your energy, mood, or even your bone health? You're not imagining things. You'll learn: Which nutrients are most commonly depleted by these medications (like magnesium, vitamin D, calcium, B12, and CoQ10) The symptoms that may be tied to nutrient deficiencies (think fatigue, brain fog, joint pain, and more) How some medications may increase cholesterol levels or raise your risk of fatty liver Why supporting your body with the right foods and lifestyle habits can make all the difference Plus, I'll share simple, whole-food nutrition strategies and daily lifestyle tips that can help you feel more energized, support your bones, balance your mood, and reduce long-term side effects—without adding overwhelm. Whether you're taking medications now or just want to be prepared, this episode is packed with practical, supportive guidance to help you stay nourished and in tune with your healing body. Resources and Studies Mentioned: Tamoxifen and Metabolic Risks Aromatase Inhibitors and Bone Health Bisphosphonates and Bone Metabolism Fulvestrant and Bone Health Herceptin and CoQ10 Support Metformin and Vitamin B12 Deficiency Subscribe, listen, and share to help other women embrace joy as their right and not just a reward.
In de podcastserie proefschriften spreekt aios interne geneeskunde dr. Tessa Steenbruggen met promovendi. In deze aflevering spreekt zij met dr. Teska Schuurman over haar proefschrift, getiteld: “Tailored care in fertile women with cancer”. Teska bespreekt de aanleiding voor haar onderzoek en verschillende studies die ze deed om de behandeling van AYA's (adolescents and young adults) te kunnen personaliseren om fertiliteit te kunnen behouden indien gewenst. Teska heeft op 24 maart haar proefschrift succesvol verdedigd aan de Universiteit van Amsterdam bij dr. Christianne Lok, dr. Nienke van Trommel en prof. dr. Frederic Amant.Referenties Boek: Even ontspannen, mevrouw – Mieke Kerkhof Tamoxifen in de zwangerschap.Literatuurstudie fertiliteit sparende chirurgie voor gynaecologische tumoren. Fertiliteit sparende chirurgie voor voorstadium cervixcarcinoom (AIS). Individualiseren van follow-up na fertiliteit sparende chirurgie voor cervixcarcinoom.
In this episode, I'm joined by Dr. Liz O'Riordan, a former breast cancer surgeon, three-time cancer survivor, and author of The Cancer Roadmap: Real Science to Guide Your Treatment Path. Liz shares the motivation behind her latest book, and the most common myths surrounding cancer, treatment, and menopause.We discuss the emotional toll of a cancer diagnosis and evidence-based insights into controversial topics like diet, turmeric, juicing, alternative therapies, and HRT after cancer. We also talk about deodorants and clean skin care and I share with Liz why I can't quite believe that ‘normal skincare' including parabens and aluminium, make no difference. Liz also breaks down key misconceptions:“Menopause after cancer is the same as natural menopause.”“Now you've had cancer, you can't just take HRT.”“Your menopause symptoms will settle down over time.”“If you're young, your body will just bounce back.”“You should just be grateful you survived.”“Tamoxifen is just a little white pill—what's the big deal?”"Sex and Intimacy Are Over After Cancer and Menopause”Episode Highlights:00:00 Intro10:19 Cancer: A Slow, Unseen Process17:24 Turmeric Supplements: Absorption Challenges20:10 Exposing the Juicing Myth25:15 Parabens: Safety in Skin Absorption31:50 Tamoxifen Side Effects35:21 Empowered Patients: Advocating for Change39:40 Struggle with Hormone Blocker Side Effects52:38 Understanding Your Motivations for Health ChoicesConnect with us:For more information and resources visit our website: www.menopauseandcancer.org Or follow us on Instagram @menopause_and_cancerJoin our Facebook group: www.facebook.com/groups/menopauseandcancerchathub
The questions answered in this podcast are listed below.They were compiled by GPs and health professionals around Australia. Is fezolinetant (Veoza) safe for use in older populations, particularly those over 70? Is fezolinetant (Veoza) listed on the PBS? If not, what is its cost? Can fezolinetant (Veoza) be taken alongside other medications, such as thyroxine? How long is it safe for a woman to continue using fezolinetant (Veoza)? Is fezolinetant (Veoza) suitable for use during the perimenopausal stage? Can fezolinetant (Veoza) be used in combination with an estrogen patch or gel for women who still experience vasomotor symptoms? Is fezolinetant (Veoza) safe to use alongside other medications, such as Oxybutynin or SSRIs? Do we have any data on interactions? Is fezolinetant (Veoza) safe for young women with aggressive breast cancer who are undergoing hormone therapy? How should a woman transition from menopausal hormone therapy (MHT) to fezolinetant (Veoza)? Can low-dose MHT be used alongside fezolinetant (Veoza)? For women who have undergone chemotherapy for breast cancer and have abnormal liver function tests post-treatment, should fezolinetant (Veoza) only be started once liver function returns to normal? Should fezolinetant (Veoza) be discontinued if liver function tests become abnormal during treatment? Is there any evidence that fezolinetant (Veoza) helps with memory and concentration issues in menopausal women? Why does fezolinetant (Veoza) cause endometrial hyperplasia? Could you confirm whether the endometrial hyperplasia observed in clinical trials was benign? Is fezolinetant (Veoza) suitable for women with a personal or family history of breast cancer? Is there any data on the effects of fezolinetant (Veoza) beyond 52 weeks? Were women from diverse ethnic backgrounds, beyond America and Europe, included in the trials? What are the recommendations regarding the effect of fezolinetant (Veoza) on liver function? How should liver function be monitored, and when should testing be repeated or the medication stopped? Can GPs prescribe fezolinetant (Veoza), or is it restricted to specialists? Is fezolinetant (Veoza) appropriate for men experiencing hot flushes due to hormone blockers for prostate cancer (off-label use)? Patient Case: I have a patient currently on fezolinetant (VEOZA®), Pristiq, and Tamoxifen. What would you recommend in this case? Patient Case: I have a mid-40s patient suffering from frequent hot flushes every 10-15 minutes, despite being on the maximum dose of MHT. Can fezolinetant (VEOZA®) be used in combination with MHT to target these hot flushes? Also, what are your thoughts on testosterone? Some of my patients use compounded testosterone to manage their symptoms. Would this be helpful for this patient, and can testosterone be used alongside fezolinetant (VEOZA®)? Patient Case: A patient started fezolinetant (VEOZA®) nearly a month ago to address almost hourly sweats and flushes. Initially, she saw a significant improvement for the first 5 days, but now the frequency and severity of symptoms have gradually returned. Is this tachyphylaxis, or should the dosage of fezolinetant (VEOZA®) be increased? Should it be used intermittently? How should I advise this patient? Host: Dr Terri Foran | Total Time: 29 mins Expert: Dr Rod Baber, Obstetrician and Gynaecologist Register for our fortnightly FREE WEBCASTSEvery second Tuesday | 7:00pm-9:00pm AEDT Click here to register for the next oneSee omnystudio.com/listener for privacy information.
In this episode of Integrative Cancer Solutions Dr. Karlfeldt is joined by Dr. Carol Lourie as she shares her extensive experience in integrative oncology, particularly focusing on breast cancer. Dr. Lourie explains how her journey into cancer care began when a close friend was diagnosed with breast cancer, which inspired her to deeply explore complementary approaches to conventional treatments. She describes how they implemented strategies like intermittent fasting, acupuncture, and herbal medicine alongside medical treatments, which led to her friend experiencing better outcomes than expected. Dr. Lourie offers a critical perspective on conventional cancer treatments, particularly questioning the widespread use of Tamoxifen and aromatase inhibitors for breast cancer. She cites research suggesting that the effectiveness of these medications may be exaggerated while their significant side effects, including increased risk of other cancers and oxidative stress, are often downplayed. This critique forms part of her broader advocacy for patient education and empowerment in making informed treatment decisions. The discussion emphasizes the importance of lifestyle factors in both cancer prevention and treatment. Dr. Lourie highlights how the standard American diet and common household products containing estrogen disruptors can contribute to cancer development. She provides practical recommendations for improving metabolic health, such as drinking green tea and avoiding certain chemicals in everyday products, stressing that these changes should be implemented gradually and sustainably. Throughout the podcast, Dr. Lourie emphasizes the critical role of mindset in cancer recovery and the need for a holistic approach that addresses both physical and emotional aspects of healing. She discusses her online coaching program called "Empowered Against Recurrence," which helps women worldwide manage their cancer treatment and recovery journey. The conversation concludes with Dr. Lourie sharing information about her resources and online courses designed to support both patients and practitioners in integrative cancer care.Dr. Carol Lourie entered integrative oncology after helping a friend with breast cancer navigate treatment using complementary approaches like intermittent fasting, acupuncture, and herbs alongside conventional medicine.Research cited by Dr. Lourie suggests that medications like Tamoxifen and aromatase inhibitors may have exaggerated effectiveness while their significant side effects, including increased cancer risks elsewhere, are often minimized.The standard American diet and common household products containing estrogen disruptors significantly contribute to cancer development according to Dr. Lourie's analysis.Dr. Lourie created an online coaching program called "Empowered Against Recurrence" to help women worldwide make informed decisions about their cancer treatment and recovery.A positive mindset and holistic approach addressing both physical and emotional aspects are essential components of effective cancer treatment and recovery.----Grab my book A Better Way to Treat Cancer: A Comprehensive Guide to Understanding, Preventing and Most Effectively Treating Our Biggest Health Threat - https://www.amazon.com/dp/B0CM1KKD9X?ref_=pe_3052080_397514860 Unleashing 10X Power: A Revolutionary Approach to Conquering Cancerhttps://store.thekarlfeldtcenter.com/products/unleashing-10x-power-Price: $24.99-100% Off Discount Code: CANCERPODCAST1Healing Within: Unraveling the Emotional Roots of Cancerhttps://store.thekarlfeldtcenter.com/products/healing-within-Price: $24.99-100% Off Discount Code: CANCERPODCAST2----Integrative Cancer Solutions was created to instill hope and empowerment. Other people have been where you are right now and have already done the research for you. Listen to their stories and journeys and apply what they learned to achieve similar outcomes as they have, cancer remission and an even more fullness of life than before the diagnosis. Guests will discuss what therapies, supplements, and practitioners they relied on to beat cancer. Once diagnosed, time is of the essence. This podcast will dramatically reduce your learning curve as you search for your own solution to cancer. To learn more about the cutting-edge integrative cancer therapies Dr. Karlfeldt offer at his center, please visit www.TheKarlfeldtCenter.com
Be sure to tune in to this episode of the Precision Health and PGX Podcast as Dr. Becky Winslow, and Dr. Angela Cassano, PharmFusion Founder and owner, discuss Dr. Cassano's personal pharmacogenomics testing and how the results impacted her breast cancer treatment, the tamoxifen and CYP2D6 pharmacogenomics clinical utility research currently available, whether CYP2D6 testing for patients prior to tamoxifen is National Comprehensive Cancer Network (NCCN) and American Society of Clinical Oncology (ASCO) recommended, and whether insurers in the United States reimburse the testing. This is a must listen for those interested in the clinical pharmacogenomics' current landscape and a pharmacist-patient's perspective about PGx testing.
Be sure to tune in to this episode of the Precision Health and PGX Podcast as Dr. Becky Winslow, and Dr. Angela Cassano, PharmFusion Founder and owner, discuss Dr. Cassano's personal pharmacogenomics testing and how the results impacted her breast cancer treatment, the tamoxifen and CYP2D6 pharmacogenomics clinical utility research currently available, whether CYP2D6 testing for patients prior to tamoxifen is National Comprehensive Cancer Network (NCCN) and American Society of Clinical Oncology (ASCO) recommended, and whether insurers in the United States reimburse the testing. This is a must listen for those interested in the clinical pharmacogenomics' current landscape and a pharmacist-patient's perspective about PGx testing.
Download Your Free Guide - 3 Things You Need to Know About Cancer: https://www.katiedeming.com/cancer-101/Do you know all the facts surrounding anti-estrogen therapy for breast cancer treatment? Many women feel scared of their own bodies after a breast cancer diagnosis, especially when told their cancer is "estrogen-driven." Dr. Deming explains why this fear is misplaced and helps you understand the natural role of hormones in your body.Dr. Katie Deming breaks down complex biology into simple terms, helping you understand what estrogen receptors really mean for your health and treatment decisions.Key Takeaways:- What estrogen-positive breast cancer really means- How hormone therapy works and its side effects- The truth about risk reduction in breast cancer treatment- Cytostatic vs. cytotoxic: why it matters- The role of lifestyle changes in healing- Questions to ask your oncologist before starting treatmentIf you're wrestling with decisions about anti-estrogen therapy or feeling pressured to start treatment immediately, Dr. Katie provides the clear, factual information you need to make confident choices. She explains how to interpret the statistics your doctor shares and what questions to ask to fully understand your options.Listen, learn, and equip yourself with knowledge to have more productive conversations with your healthcare team.Send us a text with your question (include your phone number)Watch & Listen to Born to Heal on Youtube: Click Here Transform your hydration with the system that delivers filtered, mineralized, and structured water all in one. Spring Aqua System: https://springaqua.info/drkatie Don't Face Cancer Alone"The 6 Pillars of Healing Cancer" workshop series provides you valuable insights and strategies to support your healing journey - Click Here to Enroll MORE FROM KATIE DEMING M.D. Free Guide - 3 Things You Need to Know About Cancer: https://www.katiedeming.com/cancer-101/6 Pillars of Healing Cancer Workshop Series - Click Here to EnrollWork with Dr. Katie: www.katiedeming.comFollow Dr. Katie Deming on Instagram: The.Conscious.Oncologist Take a Deeper Dive into Your Healing Journey: Dr. Katie Deming's Linkedin Here Please Support the Show Share this episode with a friend or family member Give a Review on Spotify Give a Review on Apple Podcast DISCLAIMER:The Born to Heal Podcast is intended for informational purposes only and is not a substitute for seeking professional medical advice, diagnosis, or treatment. Individual medical histories are unique; therefore, this episode should not be used to diagnose, treat, cure, or prevent any disease without consulting your healthcare provider.
Tamoxifen is a medication used to block estrogen, which is needed for some breast tumors to grow. Many survivors are prescribed tamoxifen to lower the risk of having a recurrence of breast cancer, usually after breast cancer surgery, chemotherapy and radiation. Tamoxifen can also be used for breast cancer risk reduction in women who do not have breast cancer but who are at higher risk, which was the case with today's guest. Twenty years after her mother passed away from breast cancer, Colleen Boraca learned she had two conditions that increase her chances of developing breast cancer. At the recommendation of her oncologist, she began her five-year, daily journey with Tamoxifen and is here today to share about her experience, what helped her get through struggles and how she was able to work with her doctor along the way to get the personalized care that was right for her.
In this episode of The Luke Coutinho Show, I am excited to bring you an insightful discussion with Dr. Rajiv Bhatt, an experienced surgical oncologist at HCG Cancer Center, Vadodara. Dr. Rajiv specializes in all major cancer resections, function preserving & conservation surgeries for cancer, minimally invasive oncology surgeries (MIOS), and complex surgeries for recurrent cancers. Join me as we uncover: Advances and insights in breast cancer care: Importance of tumor biology, lymphatic system, environmental estrogens (xenoestrogens), gut health, lifestyle, and more in improving cancer treatment The role of emotional health in breast cancer care: Correlation with chronic stress, suppressed emotions, and childhood trauma. The importance of screening: Prioritizing regular screenings, mammograms for breast cancer, or even simple clinical examinations Epigenetics and breast cancer risk management: Understanding BRCA1 and BRCA2 genes, challenges of genetic testing, and emerging technologies Liquid biopsies, breast cancer progression, and Tamoxifen use: Science behind liquid biopsies, cancer biology, and risks and guidelines for Tamoxifen use And much more…
Apply to the Cancer Freedom Program here: www.cancerfreedomprogram.com Of course you know that taking hormonal therapy will help prevent your cancer from coming back. But you also know the side effects are SCARY! Life changing. You don't feel like yourself. Now - you want to quit. What should you do? In this episode I'm showing you exactly what you need to know if you want to quit taking hormonal therapy for breast cancer. Whatever you decide, you have my support. Let's get you all the right information first! So let me show you how it's done. Join the Cancer Freedom Program Click HERE www.cancerfreedomprogram.com #cancersurvivor #cancerfighter #breastcancer #cancerrecovery #cancernutrition #mastectomy #tamoxifen #anastrozole #letrozole #signatara PS - Whenever you are ready, here the 2 best ways I can help you - 1) “Your A-Z Guide to Staying Cancer Free” **FREE** Click here: https://bit.ly/azcancerfree 2)Join the Cancer Freedom Program Click HERE: www.cancerfreedomprogram.com ***Let's Connect: Website: www.cancerfreedomprogram.com Instagram: https://www.instagram.com/dramymorris/ YouTube: https://www.youtube.com/channel/UCUt9... Facebook: https://www.facebook.com/dramycancer/
Although initial clinical trials of tamoxifen as a treatment of breast cancer were positive, Imperial Chemical Industries (ICI) did not believe this market would be commercially viable. The company had hoped for a contraceptive pill – tamoxifen didn't work for that – not a cancer treatment. In 1972 the higher-ups at ICI decided to cancel the research. But Dora Richardson, the chemist who had originally synthesized the compound, and her boss, Arthur Walpole, were convinced they were on to something important, something that could save lives. They continued the research in secret. Tamoxifen was eventually launched in the U.K. in 1973 and went on to become a global success, saving hundreds of thousands of lives. Dora Richardson's role in its development, however, was overshadowed by her a male colleague and all but forgotten.
In the early 1960s, chemist Dr. Dora Richardson synthesized a chemical compound that became one of the most important drugs to treat breast cancer: tamoxifen. Although her name is on the original patent, her contributions have been lost to history. In the first episode of this two-part podcast, Katie Couric introduces us to Dora's story. Lost Women of Science producer Marcy Thompson tracked down Dora's firsthand account of the history of the drug's development. This document, lost for decades, tells the story of how the compound was made and how Imperial Chemical Industries, where Richardson worked, almost terminated the project because the company was hoping to produce a contraceptive, not a cancer therapy.
In dieser Episode des Podcasts "Krebs als zweite Chance" spricht Kendra Zwiefka mit Diana über ihre persönliche Reise mit Brustkrebs. Sie thematisieren die Bedeutung der Früherkennung, die Herausforderungen vor und nach der Diagnose sowie die Erfahrungen während der Chemotherapie. Diana teilt ihre Erkenntnisse und ermutigt andere, über ihre eigenen Erfahrungen zu sprechen und Mut zu fassen. In diesem Gespräch teilen Diana und Kendra ihre Erfahrungen mit der Chemotherapie und den emotionalen Herausforderungen, die damit verbunden sind. Sie sprechen über die Unterstützung, die sie von anderen erhalten haben, die schwierigen Gespräche mit ihren Kindern und die Dankbarkeit, die sie in schwierigen Zeiten empfinden. Diana beschreibt die Auswirkungen der Chemotherapie auf ihren Körper und Geist und betont die Bedeutung von Selbstfürsorge und Unterstützung während des Heilungsprozesses. Sie reflektieren auch über die Rückkehr ins Berufsleben und die Herausforderungen, die damit verbunden sind. In diesem Gespräch reflektieren Diana und Kendra über persönliche Erfahrungen mit Krebs, insbesondere die Herausforderungen und Entscheidungen rund um die Einnahme von Tamoxifen. Diana teilt ihre Reise der Selbstakzeptanz und die Bedeutung von Unterstützung durch andere Betroffene. Sie diskutieren die Auswirkungen von Medikamenten auf die Lebensqualität und die Wichtigkeit von Vorsorgeuntersuchungen, insbesondere im Kontext des pinken Oktobers. https://www.instagram.com/dianapietscher/?hl=de Heute möchte ich dich um etwas bitten, discovering hands ist für den Publikumspreis nominiert bei der MSD und du hast die Möglichkeit bis zum 24.10.2024 für uns abzustimmen, jede Stimme zählt. Aus Behinderung wird Begabung: Das Sozialunternehmen discovering hands setzt blinde und stark sehbehinderte Frauen mit hochsensiblem Tastsinn für eine verbesserte Brustkrebsfrüherkennung ein. Nach einer neun- bis zehnmonatigen Qualifizierung zur Medizinisch-Taktilen Untersucherin (MTU) tasten MTU bis zu 50 % kleinere und 28 % mehr Tumore als Ärzt:innen in regulären Untersuchungen. Finden sie eine Auffälligkeit, klärt die verantwortliche Ärztin oder der verantwortliche Arzt sie anhand der exakten Lokalisation ab. Die MTU ersetzt keine Ärzt:innen, sondern unterstützt diese mit einer zusätzlichen wissenschaftlich empfohlenen Diagnosemethode (Taktilographie). Zudem schulen MTU in 1:1-Anleitungen zur Taktilen Selbstuntersuchung (ATS) Frauen an deren eigener Brust darin, sich selbst systematisch abzutasten. Taktilographie und ATS verbessern die Gesundheitsversorgung und verändern die Perspektive auf Menschen mit Behinderung positiv. https://www.msd.de/gesundheitspreis/voting/ Ich hoffe sehr, dass dir die Folge gefallen hat und du etwas mitnehmen konntest. Schreib mir von Herzen gern, eine positive Bewertung oder wenn du magst, abonniere meinen Podcast, um keine Folge zu verpassen. Ich würde mich riesig über deine Gedanken zu dieser Folge freuen, schau gern bei Instagram vorbei unter der aktuellen Podcast Folge und kommentiere dort deine Gefühle und Gedanken. Was konntest du für dich mitnehmen? Denk immer daran, DU bist nicht allein. Ich freue mich schon auf die nächste Folge mit dir. Bleib gesund! Danke, dass es dich gibt. Teile den Podcast mit den Menschen, die genau jetzt Mut, Kraft und Hoffnung brauchen. Hast du deine eigene Krebs Erfahrung, die du mit der Welt teilen möchtest? Oder hast du jemanden aus deiner Familie an Krebs verloren? Ich möchte jedem eine Chance geben, über das Thema Krebs zu sprechen. Fühl dich von Herzen umarmt. Deine Kendra
Dr. Shabana Dewani is board certified in Medical Oncology, Hematology, and Internal Medicine—and a joy to listen to! She breaks down the oncology process and important factors when deciding treatment. You'll be able to hear her passion for helping others ensuring they get the best treatment possible.As more women delay childbearing to their late 30s and early 40s, many young breast cancer survivors are concerned about preserving their future fertility. If you are a premenopausal woman recently diagnosed with breast cancer, here are answers to some tips you may have related to fertility following breast cancer treatment Is There Anything women Can Do to Preserve Fertility Prior to Starting Treatment? Can a woman Become Pregnant While on Tamoxifen? How Successful Are Women at Becoming Pregnant After Breast Cancer? How Long Should I Delay Pregnancy After Being Treated for Breast Cancer? SABCS 2023: POSITIVE TRIAL updateStay Connected with Dr. Deepa Halaharvi:TikTok: @breastdoctorInstagram: @drdhalaharviTBCP Instagram: @thebreastcancerpodcastWebsite: https://drdeepahalaharvi.com/YouTube: https://www.youtube.com/@deepahalaharvi5917Instagram: @thebreastcancerpodcast
**Please be aware this episode contains some mild swearing**In this bitesize episode, Dr Liz O‘Riordan joins our GP hosts Rebecca and Sarah again to talk about managing the menopausal symptoms of breast cancer treatment. Dr Liz O'Riordan - a best-selling author, speaker, podcast host and former breast cancer surgeon - talks about how patients can manage the side effects of drugs like Tamoxifen, whether GPs should prescribe HRT, practical advice on handling vasomotor symptoms, the benefits of exercise and other lifestyle measures, and why separate duvets are a complete game-changer! You can access the guidelines and studies referenced here. Accessibility: Access the full episode transcript here. If you loved this episode and would like to hear more like this, please leave a review, a rating and share the episode. GPs Talk Cancer is the podcast series from GatewayC. GatewayC is the free early cancer diagnosis resource funded by the NHS and is part of The Christie NHS Foundation Trust. Produced by Louise Harbord from GatewayC, and Jo Newsholme from Rethink Audio.DISCLAIMER: We know this podcast might be of interest to anybody, however it is aimed at primary care health professionals. All patient cases are based on real stories from our clinical practice as GPs. They are fully anonymised with no identifiable patient data. All featured statistics are accurate at the time of recording. All views expressed by guest speakers are their own. Hosted on Acast. See acast.com/privacy for more information.
ASK ME ANYTHING: My Breast Cancer Recurrence + Tips, Insights and More with Samantha & guest expert Dr. Jenn SimmonsIn August 2024, after 10 years being deemed cancer-free, a breast cancer recurrence hit me like a sledgehammer. Sharing on social media each step in these first few weeks from recurrence diagnosis through the first of two new surgeries, many of you reached out with questions.In this special BONUS EPISODE -- taken directly from the Instagram/Facebook LIVE (with my friend and special guest expert, integrative oncologist Dr. Jenn Simmons here to answer even more of your questions) -- I share my honest, very personal experiences from my primary cancer diagnosis in 2014 to how I found a lump myself for the second time around in 2024 that led to this latest shocking news.In this episode, Dr. Jenn Simmons and I will cover:Personal Journey with Recurrence: Raw insights into managing breast cancer recurrence through regular self-monitoring, along with the need to sometimes push your doctors for screening as well as the importance of truly listening to your body.Our Inner Terrain and How it Can Breed Recurrence: What to pay attention to with regard to the environment our body is creating that can allow cancer to grow and what to do to tamper it.Mircoscopic Cells Left Behind After Surgery: When should recurrence be a worry and how can we manage our fears?H. Pylori and Our Overall Gut Health: Why it matters in the cancer game.The Surprising Reality About Mammography: Dr. Simmons discusses the over-treatment of most women due to mammogram results, and she offers a new option that will become more readily available without the potential downsides, such as radiation, that currently exist.PET/CT Scans & MRIs for Detection: What is useful and what is too much or too risky? And when should we actually use these tools.Functional Tests that Conventional Oncos Don't Do: Other lab and diagnostic tests to investigate.HRT and Breast Cancer: Can we actually use it?Thermography and other modalities: How effective are they to diagnose cancer early or find it at all?Endocrine Therapy: Dr. Jenn's thoughts on Tamoxifen, aromatase inhibitors and other options for hormone blocking after diagnosis.Prevention Tips from Dr. Simmons: Practical advice on essential lifestyle changes to reduce recurrence risk and boost overall health, including some of her nutritional must-haves.+ SO Much More!ABOUT our expert guest:JENN SIMMONS, MDIntegrative Oncologist | Author | Podcast Host | founder of PerfeQTion ImagingDr. Jenn became Philadelphia's first fellowship-trained breast surgeon and spent 17 years leading the field. This personal journey led her to create Real Health MD in 2019, a practice dedicated to holistic healing for breast cancer. It integrates conventional wisdom with root cause medicine and the drivers of health: nutrition, lifestyle changes, detoxification, and stress management. Dr. Jenn's innovative approach doesn't stop there. As the founder of PerfeQTion Imaging, she is establishing safe imaging centers across the nation, armed with revolutionary technology that promises to redefine breast cancer screening. This technology is not only fast and safe but also comfortable, affordable, radiation-free, and boasts 40 times the resolution of MRI. It has received FDA clearance, signaling a new era in breast health and breast...
There continues to be great confusion regarding the impact of hormone therapy on the breast. And despite the known benefits of hormone therapy, and reassuring data regarding the impact of hormone therapy on breast cancer, most clinicians are still reluctant to prescribe it, and most women are reluctant to take it. Even more so if a woman is high risk for breast cancer or has a breast cancer diagnosis. In this episode, I am joined by Dr. Corinne Menn, a board-certified Ob GYN and menopause expert who herself had a breast cancer diagnosis when she was in her 20s. We will be reviewing the latest research on the impact of estrogen on the breast in several different scenarios. PREGNANCY post breast cancer Women who have a BREAST CANCER diagnosis Women with a FAMILY HISTORY of breast cancer Women with a BRCA MUTATION after prophylactic ovary removal The approach to therapy for women with a NEW BREAST CANCER DIAGNOSIS The use of local vaginal estrogen in women with a breast cancer diagnosis that are taking TAMOXIFEN or using an AROMOTASE INHIBITOR If a LOCAL VAGINAL ESTROGEN needs to be used at the lowest dose What to do if your DOCTOR NOT WILLING to prescribe local or systemic estrogen (list of articles to share is below) If a woman with a breast cancer diagnosis can use TESTOSTERONE for libido and other possible benefits Dr. Corrine Menn https://drmenn.com/ @drmennobgyn For more information: Episode 124 All Hormones Are Not Created Equal with Dr. James Simon Episode 65- The Dilemma of Menopause and Breast Cancer Episode 31 The TRUTH About Hormone Therapy: Does it CAUSE or Does it PREVENT Breast Cancer? Episode 28: The BEST approach for BREAST Cancer Screening and Risk Reduction with Dr. Lisa Larkin Dr. Streicher's Inside Information podcast is not intended to replace medical advice and should be used to supplement, not replace, care by your personal health care clinician. Dr. Streicher disclaims liability for any medical outcomes that may occur because of applying methods suggested or discussed in this podcast. Scientific Articles Hormone Therapy and Risk of Breast Cancer Bluming AZ, Hodis HN, Langer RD. 'Tis but a scratch: a critical review of the Women's Health Initiative evidence associating menopausal hormone therapy with the risk of breast cancer. Menopause. 2023 Dec 1;30(12):1241-1245. Bluming AZ. Introduction: Estrogen Reconsidered: Exploring the Evidence for Estrogen's Benefits and Risks. Cancer J. 2022 May-Jun 01;28(3):157-162. Hodis HN, Sarrel PM. Menopausal hormone therapy and breast cancer: what is the evidence from randomized trials? Climacteric 2018;21:521–8. Levy B, Simon JA. A Contemporary View of Menopausal Hormone Therapy. Obstet Gynecol. 2024 Mar 14. Chlebowski RT, Aragaki AK, Pan K, Mortimer JE, Johnson KC, Wactawski-Wende J, LeBoff MS, Lavasani S, Lane D, Nelson RA, Manson JE. Randomized trials of estrogen-alone and breast cancer incidence: a meta-analysis. Breast Cancer Res Treat. 2024 Apr 23. doi: 10.1007/s10549-024-07307-9. Pan K, Lavasani S, Aragaki AK, Chlebowski RT. Estrogen therapy and breast cancer in randomized clinical trials: a narrative review. Menopause. 2022 Sep 1;29(9):1086-1092. Use of Hormone Therapy in Women with a Breast Cancer Diagnosis Bluming A. Hormone replacement therapy after breast cancer: it is time. Cancer J 2022;28:183–90. Bluming AZ. Safety of systemic hormone replacement therapy in breast cancer survivors. Breast Cancer Res Treat. 2022 Feb;191(3):685-686. doi: 10.1007/s10549-021-06479-y. Fahlén M, Fornander T, Johansson H, Johansson U, Rutqvist LE, Wilking N, von Schoultz E. Hormone replacement therapy after breast cancer: 10 year follow up of the Stockholm randomised trial. Eur J Cancer. 2013 Jan;49(1):52-9. Mikkola TS, Savolainen-Peltonen H, Tuomikoski P, Hoti F, Vattulainen P, Gissler M, et al. Reduced risk of breast cancer mortality in women using postmenopausal hormone therapy: a Finnish nationwide comparative study. Menopause 2016;23:1199–203 Hormone Therapy in Women with BRCA Mutation Kotsopoulos J, Gronwald J, Karlan BY, Huzarski T, Tung N, Moller P, Armel S, Lynch HT, Senter L, Eisen A, Singer CF, Foulkes WD, Jacobson MR, Sun P, Lubinski J, Narod SA; Hereditary Breast Cancer Clinical Study Group. Hormone Replacement Therapy After Oophorectomy and Breast Cancer Risk Among BRCA1 Mutation Carriers. JAMA Oncol. 2018 Aug 1;4(8):1059-1065.. Lauren Streicher, MD is a clinical professor of obstetrics and gynecology at Northwestern University's Feinberg School of Medicine, and the founding medical director of the Northwestern Medicine Center for Sexual Medicine and Menopause. She is a certified menopause practitioner of the North American Menopause Society. Sign up to receive DR. STREICHER'S FREE NEWSLETTER Dr. Streicher is the medical correspondent for Chicago's top-rated news program, the WGN Morning News, and has been seen on The Today Show, Good Morning America, The Oprah Winfrey Show, CNN, NPR, Dr. Radio, Nightline, Fox and Friends, The Steve Harvey Show, CBS This Morning, ABC News Now, NBCNightlyNews,20/20, and World News Tonight. She is an expert source for many magazines and serves on the medical advisory board of The Kinsey Institute, Self Magazine, and Prevention Magazine. She writes a regular column for The Ethel by AARP and Prevention Magazine. Subscribe and Follow Dr. Streicher on DrStreicher.com Instagram @DrStreich Facebook @DrStreicher YouTube DrStreicherTV Books by Lauren Streicher, MD Slip Sliding Away: Turning Back the Clock on Your Vagina-A gynecologist's guide to eliminating post-menopause dryness and pain Hot Flash Hell: A Gynecologist's Guide to Turning Down the Heat Sex Rx- Hormones, Health, and Your Best Sex Ever The Essential Guide to Hysterectomy
Tamoxifen side-effects are often described by health care providers in broad terms. Natalie shares specific side-effects from taking Tamoxifen in this episode. Breast Cancer Life is a podcast about my breast cancer experience. This is for you, the person who may be facing a diagnosis, and the person who knows someone facing the reality or real possibility of a breast cancer diagnosis. Nothing could have prepared me for this lived experience. My hope is that you get a glimpse of what this life is like. Subscribe, rate, and review the Breast Cancer Life podcast. The content of this podcast is not intended to substitute professional medical advice, diagnosis, or treatment. Always consult a healthcare professional regarding your healthcare questions and concerns. This podcast contains opinions of the host. LET'S CONNECT: connect@breastcancerlife.org
Vicki Wolf was diagnosed with breast cancer at age 37. Ductal Carcinoma in SITU was successfully addressed with a lumpectomy. However, Vicki was diagnosed with the same type of cancer just two years later. Again, a lumpectomy. When Vicki was 47, she was diagnosed with Invasive Ductal Carcinoma. She survived that diagnosis but was again diagnosed with this type of breast when she was 58. That was in 2017. Vicki survived, but not before undergoing a double mastectomy. She now leads an active lifestyle and works as an advocate for men with breast cancer after her brother, Harvey Singer, was diagnosed. They formed a non-profit, His Breast Cancer Awareness.
Breast speciality oncologist Dr Claire Macaulay from Glasgow helps us understand how we can navigate difficult treatment decisions.Many women say that being on a long-term anti-hormone treatment such as tamoxifen and aromatase inhibitors is much harder than chemotherapy, radiotherapy, and surgery altogether.On this podcast we are also joined by a group of our community to give them an opportunity to ask their questions whilst being on the live show!We talk about patients not feeling they get adequate upfront discussions to make informed decisions. We talk about not being heard. Who holds the risk? What can you do to manage side effects? Dr Claire Macaulay recognises the challenges these treatments come with and talks us through our options. Dr Macaulay is also a certified sex coach supporting people in menopause to have improved sex lives. You can find her here https://www.pleasurepossibility.comAnd join her private Facebook group here Episode Highlights:00:00 Intro.09:36 Understanding symptoms can help manage breast cancer.13:07 Looking at Predict and how to use it.21:53 Dealing with cancer treatment's psychological impact.31:11 Managing menopausal symptoms with medications, side effects.36:13 Importance of NHS and community care support.42:54 Medical professionals support patient autonomy and choices.51:17 Individual doctors must decide risk and comfort.58:50 Concerns about future treatments and emotional support.About Dani:The Menopause and Cancer Podcast is hosted by Dani Binnington, menopause guide, patients advocate for people in menopause after a cancer diagnosis, and founder of the online platform Healthy Whole Me. There is lots of information out there about the menopause but hardly any if you have had a cancer diagnosis as well. Many people say to me they have no idea what their options are, who to ask for help, and that they feel really isolated in their experiences. I started this podcast because there was nothing out there when I was thrown into surgical menopause at the age of 39, which followed on from my cancer diagnosis aged 33.Through the episodes, I want to create more awareness, share information from our fabulous guest experts, doctors and other specialists in the cancer and menopause field. And of course, I will share stories from the people in our community.So that together we can work towards a better menopause experience. For all of us.More educated, better informed and less alone.Connect with us:For more information and resources visit our website: www.menopauseandcancer.org Or follow us on Instagram @menopause_and_cancerJoin our Facebook group: www.facebook.com/groups/menopauseandcancerchathub Mentioned in this episode:https://move-with-menopause-and-cancer.raiselysite.com/
In today's episode of Keeping Abreast with Dr. Jenn, we are so excited to welcome Dr. Felice Gersh, a board-certified OB GYN and integrative medicine physician. In this episode we tackle the contentious and often misunderstood relationship between estrogen and breast cancer, as Dr. Gersh dispels the myths surrounding estradiol, enlightening us on its pivotal role for maintaining metabolic and immune processes. We critique the conventional medical practice of using contraceptives to treat menstrual irregularities, the discussions uncover the importance of natural hormone rhythms for preventing inflammation and cancer. We delve into the complexities of hormone-positive tumors, the nuances of different estrogen types, and the unintended consequences of hormone suppression in breast cancer treatment.In this episode you'll:Discover the distinctions between estrone and estradiol, and their impact on breast cancer.Learn about the potential negative effects of common breast cancer medications.Challenge the long-standing misconceptions about natural estrogen's role in our bodies.Explore the benefits of phytoestrogens and a high plant-based diet to support estrogen receptors function.Recognize the importance of menstrual cycles as an essential sign of women's health and fertility.Dive into the detrimental impact of hormonal contraceptives on hormone levels and endocrine health.Emphasize the need for individualized treatment approaches to hormone therapy and the potential of "super aging."Understand the timing and considerations for perimenopause and hormone replacement therapy.00:00:35 Introduction and Welcome00:01:45 Guest Introduction: Dr. Felice Gersh00:03:32 Correcting Estrogen and Breast Cancer Misconceptions00:10:28 The Downsides of Tamoxifen and Aromatase Inhibitors00:17:11 The Critical Function of Estradiol in Women's Health00:24:06 The Case for Phytoestrogens and Plant-Based Diets00:30:57 The Ill-Preparedness of Medical Practitioners in Hormonal Balance00:38:14 Menstrual Cycles and Fertility's Impact on Long-term Health00:49:25 Hormonal Contraceptives and Their Impact on Women's Wellness00:58:13 Strategies for Managing Perimenopause and Menopause Symptoms01:05:47 Closing Advice and Where to Find Dr. GershDr. Felice Gersh is a multi-award-winning physician who is board certified in both OB GYN and integrative medicine. Dr. Gersh's extensive research and clinical experience have made her a crusader against the one-size-fits-all approach to women's health. She's an advocate for patient education, disrupting outdated medical paradigms, and providing holistic care that encompasses emotional, physical, and environmental wellbeing.To talk to a member of Dr. Jenn's team and learn more about working privately with RHMD, visit: https://calendly.com/stephanie-1031/time-to-talkTo get your copy of Dr. Jenn's book, The Smart Person's Guide to Breast Cancer, visit: https://realhealthmd.kartra.com/page/SmartPersonsGuidetoBreastCancerJoin the Facebook group: Facebook: https://www.facebook.com/groups/keepingabreastwdrjennConnect with Dr. Jenn:Website: https://www.realhealthmd.com/Facebook: https://www.facebook.com/DrJennSimmonsInstagram: https://www.instagram.com/drjennsimmons/YouTube: https://www.youtube.com/@dr.jennsimmons
I am talking about how I shopped around for the best price on Tamoxifen in this episode. The drug is generic and should not cost much, if anything. The pharmacy prices, including the mail-delivery pharmacy from my insurance company, were all over the place. Breast Cancer Life is a podcast about my breast cancer experience. This is for you, the person who may be facing a diagnosis, and the person who knows someone facing the reality or real possibility of a breast cancer diagnosis. Nothing could have prepared me for this lived experience. My hope is that you get a glimpse of what this life is like. Subscribe, rate, and review the Breast Cancer Life podcast. The content of this podcast is not intended to substitute for professional medical advice, diagnosis, or treatment. Always consult a healthcare professional regarding your healthcare needs, questions, and concerns. This podcast contains the opinions of the host. LET'S CONNECT: connect@breastcancerlife.org
Hormone Replacement Therapy (HRT) is one of the most controversial medical therapies out there. Do you know why? On this episode of Vitality Radio, Jared welcomes back his personal physician, Dr. Todd Cameron to discuss the history of HRT and the use of bioidentical hormones to optimize - not just normalize - overall health as we age. You'll learn why HRT has been demonized, what the scientific literature really says about it, and the best way to use bioidentical hormones to feel your best later in life.Dr. Todd Cameron is a naturopathic physician who offers holistic therapies to treat a wide range of illnesses and improve overall health in the Salt Lake City area, and remotely.Products:EstroSense Hormone BalancingDHEAAdditional Information:Cameron Wellness + Spa 801-486-42263378 South 2300 East, Salt Lake City, UTDr. Neal Rouzier - YouTubeEstrogen Matters by Avrum Bluming (book)Episode #377: Adrenal Fatigue: What Is It, How Do I Know If I Have It, And What Do I Do About It? With Dr. Todd CameronEpisode #347: Thyroid Health: Why Your Doctor Might Be Looking at the Wrong Numbers With Dr. Todd CameronEpisode #331: The Functional Medicine Approach to Testosterone for Men and Women with Dr. Todd Cameron NMD#397: Understanding Hormonal Imbalances - Adrenals, Endocrine Disruption, PCOS, Thyroid, and More with Dr. Marita SchauchEpisode #313: Women's Health and Hormone Balance, from PMS to Menopause and Beyond with Niki WolfeVisit the podcast website here: VitalityRadio.comYou can follow @vitalityradio and @vitalitynutritionbountiful on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Please also join us on the Dearly Discarded Podcast with Jared St. Clair.Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
CardioNerds meet with fellows from The Christ Hospital, Drs. Hanad Bashir, Hyunsoo Chung, and Dalia Aziz to discuss the following case that highlights angioleiomyoma: A 60-year-old woman with a past medical history significant for breast cancer (on tamoxifen) presented as a transfer to our facility for a clot-in-transit. She had initially presented to the outside hospital after progressive dyspnea on exertion and recent syncope. She was found on an echocardiogram to have a right atrial mass spanning into the right ventricle. CTA of the chest and abdomen/pelvis demonstrated extensive thrombus burden spanning from the IVC into the right ventricle. She was transferred to our facility for intervention. Endovascular attempts were unsuccessful, at which point she underwent surgical thrombectomy. Gross examination of the mass revealed a cylindrical shape, homogeneous tan color, rubbery soft tissue, measuring 25.5 cm in length and 2.3 cm in diameter. Histology confirmed the presence of angioleiomyoma. A second, smaller mass (5.2cm long and 4mm in diameter) was removed from under the tricuspid valve, with histology consistent with leiomyoma. Estrogen receptor and progesterone receptor staining were strongly positive, leading to the discontinuation of tamoxifen. Given the presence of uterine fibroids identified on the CT scan, there was concern about a uterine origin. A hysterectomy is planned for her in the near future. Expert commentary is provided by Dr. Wojciech Mazur. Episode audio was edited by student Dr. Adriana Mares. US Cardiology Review is now the official journal of CardioNerds! Submit your manuscript here. CardioNerds Case Reports PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Case Media - The Tall Tail Heart: Angioleiomyoma – The Christ Hospital Pearls - The Tall Tail Heart: Angioleiomyoma – The Christ Hospital Although evaluation of cardiac mass by echocardiography can provide information such as size, location, and morphology, adjunctive cross-sectional imaging may be used depending on the need for further temporal resolution (CT) or tissue characterization via cardiac MRI (CMR). If suspicious for elevated metabolic activity, there should be consideration of FDG-PET. Tamoxifen (a selective estrogen receptor modulator) is an agent used for breast cancer therapy. However, its use has been associated with endometrial hyperplasia, uterine fibroids, endometrial and uterine malignancy. Increased risk of malignancy has been seen more often in post-menopausal women and is dose and time-dependent. Clot in transient is a mobile thrombus, typically within the right heart structures. It is estimated to occur in 4-18% of patients with pulmonary embolism and is associated with elevated morbidity and mortality. Treatment includes surgical embolectomy, endovascular embolectomy, systemic thrombolysis, catheter-directed thrombolysis, or systemic anticoagulation. Angioleiomyoma is a rare benign pericystic tumor that most commonly affects the extremities. There are case reports of other affected sites, including the uterus. Invasion into the cardiac structures is exceedingly rare. The only established treatment for angioleiomyoma is surgical resection. Show Notes - The Tall Tail Heart: Angioleiomyoma – The Christ Hospital Syncope Syncope is a transient loss of consciousness secondary to reduced blood flow to the brain. Often, certain presentations are mislabeled as syncope, such as seizure disorders, posttraumatic loss of consciousness, and cataplexy. An organized diagnostic approach should be used to reduce hospital admissions and medical costs and increase diagnostic accuracy. Syncope can be divided into five general subgroups. 1) Neurally mediated reflex syncope (carotid sinus syndro...
I am pleased to invite Dr. Corinne Menn to the show today. Dr, Menn is a certified gynaecologist, a North American Menopause Society certified menopause specialist and a breast cancer survivor herself who decided to take HRT. Dr. Menn shares her struggles of survivorship with us, talks us through her decision-making processes of over 20 years of being a cancer survivor and she tackles this controversial topic with us.We talk about: Dr. Menn's personal journey of being diagnosed with breast cancer as a young medical student.Why tamoxifen is not a hormone blocker.Having a drug break to try for a baby.The different experiences of being on endocrine treatment. Why we don't always make decisions based on facts alone.Why she decided that HRT was worth a try.You can find Dr. Corinne Menn here. Or here on her Instagram. Subscribe to the Menopause and Cancer YouTube Channel here.Episode Highlights:[07:35] Dr Menn paused endocrine therapy.[13:45] Tamoxifen blocks receptor stimulation, which has multiple effects.[29:15] We should focus on science, evidence; concern for survivors.[35:16] Lack of communication on treatment side effects is unacceptable.[51:14] Get informed about your breast cancer treatment.[55:57] Breast cancer survivors deserve informed decision-making.About Dani:The Menopause and Cancer Podcast is hosted by Dani Binnington, menopause guide, patients advocate for people in menopause after a cancer diagnosis, and founder of the online platform Healthy Whole Me. There is lots of information out there about the menopause but hardly any if you have had a cancer diagnosis as well. Many people say to me they have no idea what their options are, who to ask for help, and that they feel really isolated in their experiences. I started this podcast because there was nothing out there when I was thrown into surgical menopause at the age of 39, which followed on from my cancer diagnosis aged 33.Through the episodes, I want to create more awareness, share information from our fabulous guest experts, doctors and other specialists in the cancer and menopause field. And of course, I will share stories from the people in our community.So that together we can work towards a better menopause experience. For all of us.More educated, better informed and less alone.Connect with Dani:Instagram @healthywholeme Facebook: @healthywholeme Website: menopauseandcancer.org Join Dani's private Facebook group: https://www.facebook.com/groups/menopauseandcancerchathubFor oodles of inspiration, healthy recipes, yoga classes and all round positivity go to her website: https://www.healthywholeme.com/
In this JCO Article Insights episode, Davide Soldato provides summary on two articles published in the November issues of the Journal of Clinical Oncology. The first article provides data on the prognostic effect of physical exercise on overall mortality and cancer-related mortality in a pan-cancer analysis of the PLCO study. The second article provides data regarding the impact of BMI on treatment-related adverse events and adherence to Palbociclib in the PALLAS trial. Overall, results of these study support the need to conduct studies investigating lifestyle behavioral factors and their impact on outcomes in survivors of and patients diagnosed with cancer. TRANSCRIPT The guest on this podcast episode has no disclosures to declare. Davide Soldato: Welcome to the JCO Article Insights episode for the November issue of the Journal of Clinical Oncology. This is Davide Soldato, your host, and today, I will be providing a summary on two articles focused on the impact of exercise on cancer prognosis and of BMI on treatment side effects. In the first article titled Pan-Cancer Analysis of Postdiagnosis, Exercise, and Mortality, Lavery and colleagues investigated whether higher exercise was associated with a reduced risk of mortality among individuals diagnosed with cancer. The authors conducted a pan-cancer analysis using data from the Prostate, Lung, Colorectal, and Ovarian cancer screening study or PLCO, using data from a questionnaire that was administered to participants in the study at a median of nine years after initial randomization. The questionnaire including 12 questions related to physical activity, both occupational and non-occupational. Of these 12 questions, four were used to assess the prognostic impact of moderate and strenuous exercise evaluated both in terms of frequency, so a number of sessions per week, and duration of exercise sessions. The exposure to exercise was defined according to international guidelines, and patients were so divided among those who had a moderate intensity exercise defined as at least four days per week with each session on average for 30 minutes in duration, and strenuous intensity exercise equal or more to two days per week with each session on average of at least 20 minutes in duration. So, based on this definition, the patients were categorized as either exerciser, if they were meeting the recommendation or non-exercisers. Additionally, to assess the existence over those response relationship between exercise and mortality, the authors further categorize patients on a four level scale as reporting no exercise, exercise, not meeting recommendation, meeting recommendation, or exceeding recommendation. The primary endpoint of the study was all-cause mortality, and secondary endpoints included cancer mortality and mortality from other causes. This study included more than 11,000 patients diagnosed with cancer. 38% of them reported meeting guidelines recommendation with a median of 44 and 19 minutes spent in moderate and strenuous exercise respectively. Individuals belonging to the group of exerciser were more frequently male, non-smokers, and with a lower prevalence of cardiovascular diseases. The most common cancer diagnosis were prostate cancer, breast cancer, and colon cancer observed respectively in 37%, 20%, and 7% of the participants. Patients who died within six months from the completion of the questionnaire were excluded from this study. A median follow-up time between this landmark point and the last follow-up was 11 years. More than 4,500 deaths were observed in this period, and less than half were related to cancer meeting. Meeting exercise recommendation was associated with a 25% risk reduction in all-cause mortality, a 21% risk reduction in cancer mortality, and a 28% risk reduction in mortality from other causes. In particular, five-year cancer mortality rate was 12% among exerciser and 16% among non-exerciser. Interestingly, the positive prognostic effect of exercise was observed starting within the first five years of observation, but persisted up to 20 years afterwards. An inverse to those response relationship between exercise and mortality was observed, so increasing exercise was overall associated with incremental reduction in the risk of death. The authors compared patients reporting no exercise with those reporting exercise under at the recommendation or over the recommendation. For all-cause mortality, the risk reduction was equal to 25% among those reporting exercise below the recommendation, and increased to 35 and 36% among those meeting and exceeding recommendation respectively. Similar results were observed for cancer mortality, risk reduction ranged from 19% in those reporting exercise below recommendation, up to 33% for those exceeding recommendation. Finally, the authors investigated the effect of exercise on mortality by cancer type, and observed a significant reduction in cancer mortality only for head and neck cancer and renal cancer. While reduction all-cause mortality and mortality from other causes were observed across a wide range of cancer, including breast, endometrial, and hematopoietic and prostate. The study confirms previous findings by showing an inverse relationship between higher level of exercise and lower risk of all-cause mortality, and provides novel insights on the topic by reporting that those response association, data on other causes of death, and edited analysis by cancer site diagnosis. All limitation of the study is related to the generalizability of the findings. The study included only patients that were alive at a median of 4.5 years after cancer diagnosis, which might have applied to selection of patients with good prognosis, and thus, reducing the number of cancer mortality events. Additionally, these patients were willing to complete an additional questionnaire in the context of the trial, which might be related to a higher motivation in engaging in healthy lifestyle behaviors. The study did not replicate previous findings observing a reduction in cancer mortality for breast, colon, and prostate cancer, among those reporting higher exercise. Although this might be related to the inclusion of long-term survivors in the study. In the second article titled Impact of BMI in Patients With Early Hormone Receptor-Positive Breast Cancer Receiving Endocrine Therapy With or Without Palbociclib in the PALLAS trial, Dr. Pfeiler and colleagues investigated the impact of BMI on side effects, adherence to treatment, and efficacy of palbociclib in the PALLAS trial. Just as a reminder, PALLAS is a randomized clinical trial that investigated whether the addition of two years of palbociclib to standard endocrine therapy in patients treated for stage two, three hormone receptor-positive HER2-negative breast cancer could improve invasive disease-free survival. Previous report of the trial showed that palbociclib did not improve invasive disease-free survival compared to endocrine therapy alone. More than 5,500 patients were included in this analysis, and among them, more than two third at a BMI equal or over 25 diagnoses with 32% being overweight and 30% obese. Overweight and obese patients were more frequently older and coming from North America rather than from Europe. In line with the age difference, normal weight patients were treated more frequently with Tamoxifen alone or in combination with ovarian function suppression or with aromatase inhibitors in combination with ovarian function suppression. No differences in tumor characteristics was observed according to BMI. However, there were some minor differences regarding the type of surgery and administration of chemotherapy. The authors observed that side effects of palbociclib were significantly different according to BMI and in particular, they observed a lower incidence of a hematological toxicity among overweight and obese patients. Conversely, higher rates of arthralgia, nausea and diarrhea were observed among overweight and obese patients, both in the palbociclib and in endocrine therapy alone. In particular, regarding hematological toxicity, the authors observed that overweight and obese patients experienced a significantly lower incidence of overall neutropenia, grade 3 and grade 4 episodes of neutropenia. For example, looking at grade 3 neutropenia, the incidence was equal 44% in the obese population versus 64% in the normal weight cohort. Differences in incidence of neutropenia remains significant even when adjusting for confounding factors, including previous administration of chemotherapy, age, ECOG performance status, and race ethnicity. Furthermore, a lower incidence of overall thrombocytopenia was observed in the overweight and obese cohort. The lower incidence of hematological toxicity led to significant differences in those reduction, early discontinuation, and relative dose intensity for palbociclib. At six months, only 29% of obese patients reduced to those of palbociclib compared to 50% in the normal weight cohort. Similarly, only 20% of obese patients permanently stopped palbociclib compared to 35% in a normal weight group. Finally, the risk of palbociclib early discontinuation was 25% lower for each additional 10 units of BMI, even when accounting for additional potential co-founders. As a consequence of a lower dose reduction and lower rates of early discontinuation, the relative dose intensity for palbociclib was significantly higher among overweight and obese patients compared to normal weight ones. Efficacy of palbociclib was not different according to BMI, neither in the palbociclib bar, nor when assessing patients in both arms. However, these analyses are performed with a relatively short, medium follow-up time, and a low number of events. So, in conclusion, this report from the PALLAS trial shows that higher BMI was associated with a more favorable safety profile, especially regarding hematological toxicity, and a lower risk of treatment discontinuation. These findings are in line with previous data obtaining the metastatic setting with other CDK4/6 inhibitors, and support the existence of a different pharmacodynamic profile influenced by BMI that translates in a more favorable toxicity profile. At present, differences in BMI do not seem to affect palbociclib efficacy, but further analysis with additional follow-up time and events, as well as by type of endocrine therapy administered are planned in the PALLAS study. That concludes this episode of JCO Article Insights. In these episodes, we summarized findings from two studies, the first titled, Pan-Cancer Analysis of Postdiagnosis, Exercise and Mortality by Lavery and colleagues. This trial shows that higher level of exercise are associated with lower risk of all-cause cancer specific and other cause mortality, although with some differences according to cancer site. The second article titled Impact of BMI in Patients with Early Hormone Receptor-Positive Breast Cancer Receiving Endocrine Therapy With or Without Palbociclib in the PALLAS trial by Dr. Pfeiler and colleagues observed a significant different side effect profile for palbociclib according to BMI, but no differences in efficacy. This is Davide Soldato, thank you for your attention and stay tuned for the next episode of JCO Article Insights. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions.Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.
Despite being incredibly healthy and believing she was living the life we were promised (since we were told as little girls that we could have it all), receiving a breast cancer diagnosis was the last thing Tessa Guevara expected. She's here with me today to talk about her story of surviving, thriving, and truly living her best life after a breast cancer diagnosis. Ready to feel inspired? Let's dive in!This episode covers:How we, as women, can fall out of balance in our health Sympathetic (fight or flight) vs. Parasympathetic (rest and repair) nervous systems and the downside to “sweating the small stuff”Tessa's hormone replacement journeyThe type of estrogen you need to be taking if you have a history of breast cancerSide effects from cancer meds that your doctor isn't telling you about The transition from Patient to SurvivorOne piece of advice I was told in residency that I still follow today And more!More about Tessa:For the past 20+ years, Tessa Guevara has been a health care clinician working as a Registered Nurse for 8 years and then a Certified Registered Nurse Anesthetist for 15 years, respectively. Tessa has always felt that bad food and disease have a relationship and in May of 2017, she discovered more proof and a platform that really helped her dig into it. She took the plunge and became a certified FASTer Way to Fat Loss® coach. This move not only opened the door to help other women eat MORE and workout LESS, but it also gave her exposure to nutrition in a way that she had never experienced before. And it was a game changer.That program was just the tip of the iceberg. Tessa became obsessed with learning and changing her own views on nutrition to the point of pursuing a functional nutrition certification. She felt like this was the right time to get this right in her own life. She is now a functional nutritionist. As a certified nutritional therapy practitioner, she has the tools to provide the proper testing and personalized protocol needed to discover the root causes of health concerns and heal them!Connect with Tessa:Tessa's Website: https://www.tessaguevara.com/my-storyTessa's Instagram: https://www.instagram.com/tessa_guevara/To talk to a member of Dr. Jenn's team and learn more about working privately with RHMD, visit: https://calendly.com/stephanie-1031/time-to-talkTo get your copy of Dr. Jenn's book, The Smart Person's Guide to Breast Cancer, visit: https://realhealthmd.kartra.com/page/SmartPersonsGuidetoBreastCancerJoin the Facebook group: Facebook: https://www.facebook.com/groups/keepingabreastwdrjennConnect with Dr. Jenn:Website: https://www.realhealthmd.com/Facebook: https://www.facebook.com/DrJennSimmonsInstagram: https://www.instagram.com/drjennsimmons/YouTube: https://www.youtube.com/@dr.jennsimmons
Dr. Katrina Lewis is a Double Board Certified Anesthesiologist, Interventional Pain Medicine Expert, Board Certified through American Academy of Anti-Aging and Restorative Medicine and also holds a degree in Clinical Nutrition (among many more accolades and accomplishments). Dr. Lewis overcame breast cancer once and is thriving now— during stage 4. She dives into what she wished she knows now when she was first diagnosed... This episode is highly controversial and you are not encouraged to listen if you find the topics of chemotherapy, mammograms, and big pharma offensive. 12:20: Anthrax vaccine 12:29: Smoking — nicotine can make pain worse 18:39: Why neurosurgeons won't operate on smokers 23:17: CBD for pain, anxiety, and sleep 32:17: Treating headaches and pelvic pain 33:46: Platelet Rich Plasma (PRP) 36:36: PRP before getting surgery 37:27: COOLIEF 46:52: Supplementation for neuropathy 49:59: Complex Regional Pain Syndrome 51:26: People saved from unnecessary spine surgeries 57:14: **SimplyO3 Home ozone generator** Use code: ASHLEYDEELEY to save 10% 1:00:28: Hyperbaric ozygen therapy (HBOT) 1:03:30: Lung cancer and genetic testing 1:04:55: Nine of the ten chemotherapy drugs are Class 1A carcinogens 1:05:59: Thomas Lodi - Oasis of Healing in Mesa, AZ 1:06:02: Dr Paul Anderson (and his book, Cancer: The Journey from Diagnosis to Empowerment) 1:06:04: Frank Shallenberger in Nevada 1:07:03: Tamoxifen and Endometrial cancer 1:07:34: One centimeter squared tumor contains one billion cancer cells... the moment you pierce it with a needle... 1:10:54: Cryoblation for breast cancer 1:11:53: Heat your body up if you have cancer (saunas are great) 1:14:15: If she had to do it over again... 1:14:26: Mammograms and radiation 1:14:41: Thermography 1:15:34: Susan B. Komen + financial interest in mammorgram machines 1:17:53: Rachel Carson (creator of EPA) 1:20:28: Cancer and The New Biology of Water book 1:21:23: Pulsed Electromagnetic field mat (PEMF) 1:22:27: Where Katrina found her Naturopath 1:22:48: Diindolylmethane (DIM) found in cruciferous vegetables 1:24:24: PolyMVA Store 1:24:37: Pure Encapsulations 1:24:56: Simply Organic ginger 1:25:14: High dose Vitamin C IV drip (such as PUR-C, mentioned in episode 20 by Dr. Blodgett) 1:26:30: The Metabolic Approach to Cancer by Dr. Nasha Winters 1:26:57: Low carb diet 1:30:39: Visit websites such as: The Truth About Cancer Going Integrative Plus Sanoviv in Mexico Paracelsus Clinic in Switzerland 1:31:42: Quantum biofeedback machine (SCIO (Scientific Consciousness Interface Operating system) 1:35:16: Harold Saxton Burr, Ph.D. 1:36:30: PEMF 'loop' 1:37:38: Hydrogen machine for water / hydrogenated water Additional Resources to Learn More About Dr. Katrina Lewis:Bringing Method to the Madness Great Falls doctor is injecting new hope for PTSD patientsDr. Katrina Lewis Anti-Aging/Metabolic Medicine Fellowship (2016)Former 'About Me' at Logan HealthTop Doctor DirectoryPain Clinic of Spokane - Articles by Dr. LewisAcademia Articles Journal of Pain Research & Journal of Addiction Research & Therapy: A Prospective, Longitudinal Study to Evaluate the Clinical Utility of a Predictive Algorithm to Detect Opioid Use Disorder in Chronic Pain Patients International Journal of Biomedical Science: Adding Genetic Testing to Evidence-Based Guidelines to Determine the Safest and Most Effective Chronic Pain Treatment for Injured Workers PM&R (Physical Medicine and Rehabilitation): A Typical Hip Pain in a Female Runner: A Case Report The Clinical Journal of Pain: Acupuncture for Lower Back Pain: A Review Dr. Lewis is not on social media; reach out to me if you have further questions. Find me at @ashley_deeley on instagram or email me: hello@ashleydeeley.com This podcast is for informational purposes only and does not replace or act as medical advice. Always consult with your physician.
Preeti Sudheendra, MD, is a breast cancer medical oncologist at Ohio State/The James Cancer Hospital and has been in practice for almost 15 years. She also has an expertise in seeing patients who may be at high risk for developing breast cancer in the future due to genetic or other predispositions. Dr. Sudheendra has been involved with the American College of Lifestyle Medicine since 2022 and is the incoming co-chair for the ACLM Breast Cancer Subcommittee. Links:Connect with Dr. Sudheendra on Twitter/X and LinkedIn
Ever wondered how a breast cancer diagnosis affects not just the patient but the entire family? What can you do to navigate the complex healthcare system and maintain a sense of normalcy in your life? This podcast episode explores the journey of a breast cancer survivor and offers valuable insights into dealing with a diagnosis. Our guest Christa, a breast cancer survivor, shares her remarkable journey from diagnosis to thriving. She speaks about the emotional and physical challenges she faced, her experience with taking Tamoxifen, and the impact on her family, especially her children. With over a decade of personal experience, Christa discusses her transformation into a board-certified health coach and nutrition specialist. She also talks about the importance of advocacy, helping others navigate the complex healthcare system. From the emotional toll of the diagnosis and treatment to the practical challenges like dealing with insurance companies, Christa's story is a testament to resilience and determination. Key Takeaways: Facing a cancer diagnosis requires clarity on your needs and desires to effectively manage your journey. Accepting help from others is easier when you clearly outline your treatment plan, childcare, and home care requirements. Becoming an advocate for your healthcare can make the journey smoother and more manageable. Resources: Christa Tyler's Website Christa Tyler on Instagram Dr. Cynthia Hauver's website: drcynthiah.com and you can find me on the socials @dr.cynthiahawver
Interview with Seema A. Khan, MD, author of Presurgical Oral Tamoxifen vs Transdermal 4-Hydroxytamoxifen in Women With Ductal Carcinoma In Situ: A Randomized Clinical Trial. Hosted by Amalia Cochran, MD. Related Content: Presurgical Oral Tamoxifen vs Transdermal 4-Hydroxytamoxifen in Women With Ductal Carcinoma In Situ
Interview with Seema A. Khan, MD, author of Presurgical Oral Tamoxifen vs Transdermal 4-Hydroxytamoxifen in Women With Ductal Carcinoma In Situ: A Randomized Clinical Trial. Hosted by Amalia Cochran, MD. Related Content: Presurgical Oral Tamoxifen vs Transdermal 4-Hydroxytamoxifen in Women With Ductal Carcinoma In Situ
Many women say that being on a long-term anti-hormone treatment such as tamoxifen and aromatase inhibitors is much harder than chemotherapy, radiotherapy, and surgery altogether.So I've invited breast speciality oncologist Dr. Claire Macaulay from Glasgow onto the podcast to answer your questions. We're also joined by a group of our community to join us for this recording so that they get to ask their questions whilst being on the live show!Both tamoxifen and aromatase inhibitors (AIs) are hormonal therapies used in the treatment of oestrogen-positive (ER-positive) breast cancers to stop tumour growth and recurrence and to treat cancer that has come back after initial treatment or that has spread to other parts of the body.These treatments come with the benefits of reducing the risks of cancer recurrence and they also come with a host of unwanted side effects. Sometimes, these can very much reduce a woman's quality of life. Dr. Claire Macaulay recognises the challenges these treatments come with and talks us through our options. Dr. Macaulay is also a certified sex coach supporting people in the menopause to have improved sex lives. You can find her here https://www.pleasurepossibility.comAnd join her private Facebook group here About Dani:The Menopause and Cancer Podcast is hosted by Dani Binnington, menopause guide, patients advocate for people in menopause after a cancer diagnosis, and founder of the online platform Healthy Whole Me. There is lots of information out there about the menopause but hardly any if you have had a cancer diagnosis as well. Many people say to me they have no idea what their options are, who to ask for help, and that they feel really isolated in their experiences. I started this podcast because there was nothing out there when I was thrown into surgical menopause at the age of 39, which followed on from my cancer diagnosis aged 33.Through the episodes, I want to create more awareness, share information from our fabulous guest experts, doctors and other specialists in the cancer and menopause field. And of course, I will share stories from the people in our community.So that together we can work towards a better menopause experience. For all of us.More educated, better informed and less alone.Connect with Dani:Instagram @healthywholeme Facebook: @healthywholeme Website: menopauseandcancer.org Join Dani's private Facebook group: https://www.facebook.com/groups/menopauseandcancerchathubFor oodles of inspiration, healthy recipes, yoga classes and all round positivity go to her website: https://www.healthywholeme.com/
Do you want to hear a story about a crime-fighting pharmacist? This episode has it! This month's VIP (very important person), Shabbir Safdar, has served as the Executive Director of the Partnership for Safe Medicines since 2017. He shares some incredible information about drug safety and supply chain security, an update on importing medication from Canada, and the fight against counterfeit drugs. Also, hear an amazing story about a pharmacist in Texas who actually caught and stopped a ring of counterfeit HIV medicines. Upcoming NPA Events: October 5-7 - Virtual Fall Pharmacy Forum October 10 - AE Tour - Wayne October 11 - Resident Student Happy Hour! October 26 - Nebraska Pharmacy Foundation Fundraiser: Charcuterie Workshop November 2 - ACE Tour - Gretna November 4 - NPA Tailgate November 11 - ACE Tour - Beatrice Partnership For Safe Medicines Links: Website | Info for Pharmacists | TikTok | YouTube | Shabbir Safdar ___ Connect with the Pharm Girls | Facebook | Instagram | LinkedIn To learn more about Nebraska Pharmacy Association visit https://www.npharm.org/
In this two-part journey, Shauna and Rosalina detail the mental, emotional, financial, and physical struggle of hormone therapy through — and following — treatment. At points, Shauna felt like she was one continuous experiment, fighting fire with fire and piling on medications that put her in a dark place for the better part of a year. Rosalina and Shauna are on their five-year medication regimen, with Rosalina having experienced menopausal-like symptoms of insomnia, hot flashes, brain fog, and joint pain that lasted over a year and a half.With the help of a new workout regimen, Rosalina no longer experiences joint pain, but her other symptoms vary from week to month. She has found other coping mechanisms to help with insomnia and shared them with Shauna, who has also been having sleepless nights and hot flashes. Shauna shifted gears with a new oncologist at the end of 2022, who — along with a newfound support group — guided Shauna with empathy and compassion as she navigated the oftentimes treacherous lanes of hormonal therapy.Episode Timestamps:[00:01:35] Housekeeping Items/Updates[00:02:18] Rosalina's Update - Side Effects of Hormone Therapy[00:07:19] Rosalina's Brain Fog and Fatigue[00:11:28] Shauna's Joy of Having a Period Again[00:15:39] Shauna's Update - Revisiting Hormone Therapy[00:20:13] Starting Verzenio[00:24:52] Diarrhea and It's Many Joys[00:28:54] To Guinea Pig or Not To Guinea Pig[00:35:59] Side Effects and Symptoms[00:39:51] Advice to Your Former SelfListen to Our Hormone Therapy Part 1 episode in S2Click here to leave us a voicemail about what advice would you give to individuals or organizations who are considering supporting breast cancer awareness and research efforts through donations or other means?Resources:The Monarch Trial: https://pubmed.ncbi.nlm.nih.gov/32954927/Verzenio Copay Assistance: https://www.verzenio.com/savings-supportIf you enjoy this episode, please share it with your friends. Help us reach more women by subscribing and rating us on Apple Podcast, Spotify, and YouTube.You can follow us on Instagram @TYFTSpodcast and email us at tyftspodcast@gmail.comPlease consider donating to our “Buy Me A Coffee” page. Your generous support will greatly assist us in continuing to produce quality content for our listeners. Every donation will get a shoutout on our podcast, as well as a free TYFTS sticker.www.buymeacoffee.com/tyftspodcastIf you want to submit a quote about your breast cancer journey, submit one here: Submit A Quote
Chapter 1 What's The Emperor of All Maladies"The Emperor of All Maladies: A Biography of Cancer" is a non-fiction book written by Siddhartha Mukherjee, an Indian-American physician and researcher. Published in 2010, the book provides a comprehensive history of cancer, focusing on its origins, treatment methods, and the ongoing battle against the disease. It explores the scientific, social, and personal aspects of cancer, and delves into the stories of patients, researchers, and physicians who have shaped the fight against cancer throughout history. "The Emperor of All Maladies" won the Pulitzer Prize for General Nonfiction in 2011 and has been widely acclaimed for its narrative style and depth of research.Chapter 2 Why is The Emperor of All Maladies Worth ReadThe Emperor of All Maladies by Siddhartha Mukherjee is worth reading for several reasons:1. Comprehensive and engaging storytelling: Mukherjee tells the history of cancer in a captivating and accessible manner. He weaves together personal stories of patients and their struggles with insightful scientific explanations, making the book suitable for both lay readers and those with a scientific background.2. In-depth exploration of a complex disease: Cancer is a multifaceted and elusive disease, and Mukherjee takes the time to explore its many aspects. He discusses its origins, the various treatments developed over the years, the social and political factors surrounding cancer research, and the implications for the future.3. Humanizes the disease: By sharing personal accounts of patients and their experiences, Mukherjee puts a face to the disease. This human perspective helps readers empathize with those affected by cancer and understand the devastating impact it has on their lives.4. Explores the triumphs and failures: The book covers both breakthroughs and setbacks in cancer research, highlighting the perseverance and determination of scientists throughout history. It gives readers a deeper appreciation for the complexities involved in fighting this disease.5. Raises important questions: The Emperor of All Maladies makes readers think about the ethical dilemmas faced by doctors and researchers in the field of cancer. It prompts discussions about the balance between scientific progress and patient welfare, the cost of treatment, and the role of societal attitudes toward cancer.Overall, The Emperor of All Maladies is a thought-provoking and informative book that offers a comprehensive overview of cancer, its history, and the ongoing efforts to understand and combat it.Chapter 3 The Emperor of All Maladies SummaryThe Emperor of All Maladies: A Biography of Cancer is a non-fiction book by Siddhartha Mukherjee published in 2010. The book provides a comprehensive and engaging narrative of the history, biology, and treatment of cancer.Mukherjee begins the book by tracing the origins of cancer, exploring its appearances in ancient civilizations and his own personal encounters with patients as an oncologist. He delves into the roots of cancer research, discussing key breakthroughs such as the discovery of DNA and the first successful treatments of childhood leukemia.The author then navigates through the evolution of cancer treatment, from early surgeries and radiation therapy, to the development of chemotherapy drugs like Methotrexate and Tamoxifen. He also explores the rise of cancer organizations such as the American Cancer Society and the National Cancer Institute, highlighting their impact on research and public awareness.Mukherjee also sheds light on the various challenges and controversies surrounding cancer research and treatment. He discusses the ethical dilemmas faced by...
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
On this podcast episode, I discuss tamoxifen pharmacology, adverse effects, drug interaction, and much more. Tamoxifen is converted to a more active compound in the body by CYP2D6. CYP2D6 inhibitors such as paroxetine, fluoxetine, or bupropion can essentially reduce the effectiveness of tamoxifen. Hot flashes are a common adverse effect of tamoxifen and I discuss a few pharmacologic options to manage this adverse effect.
Do you just not feel like yourself anymore, even though your lab tests say everything is “normal?” Does your significant other call you after work each day to check your mood and whether they need to suit up in some armor before coming home? This is exactly what my guest today was dealing with! Dr. Deb Matthew is a conventionally trained doctor who, once learning more about hormones and how they were affecting her personally, left her pediatric practice and was retrained in functional medicine. Today she's now known as the Happy Hormone Doctor and we are going to talk about her journey.We will talk more about:How your lab work does not always tell the true story, especially when only looking at one tiny part of the potential issueThe surprising reason doctors often downplay your health issues or symptomsWhy people think hormones will cause breast cancerHormone replacement therapy -- who's it for and how it works If Tamoxifen is really the answer for breast cancer patients Using a holistic approach to best produce and metabolize estrogenAnd more!More about Dr. Deb: Deb Matthew MD, America's Happy Hormones Doctor, wears many hats as a best-selling author, international speaker, private practice doctor, wife, and mom of 4 boys. She helps her patients restore their health by addressing the root cause of their symptoms (including hormone imbalances!) instead of just treating diseases with drugs.After suffering for years with exhaustion and irritability that prevented her from being the wife and mom that she wanted to be, she refocused her medical career to help others get their hormones back in balance.Dr. Deb combined her background in medicine with her interest in fitness and nutrition to create a complete medical wellness approach using scientifically-based treatments to help her patients restore their energy, libido, mood, and memory, as well as lose weight and discontinue many of their prescription medications.As Past- President of the North Carolina Integrative Medicine Society, she helps support Integrative/Functional Medicine practitioners in the community and has a goal of shifting the standard of care in medicine towards creating wellness.Connect with Dr. Deb:Dr. Deb's Website: https://drdeborahmatthew.com/Signature Wellness: https://signaturewellness.org/This is Not Normal: A busy woman's guide to symptoms of hormone imbalance (book - download a free copy): https://signaturewellness.org/fullbookrequestTo talk to a member of Dr. Jenn's team and learn more about working privately with RHMD, visit: https://calendly.com/stephanie-1031/time-to-talkTo get your copy of Dr. Jenn's book, The Smart Person's Guide to Breast Cancer, visit: https://realhealthmd.kartra.com/page/SmartPersonsGuidetoBreastCancerJoin the Facebook group: Facebook: https://www.facebook.com/groups/keepingabreastwdrjennConnect with Dr. Jenn:Website: https://www.realhealthmd.com/Facebook: https://www.facebook.com/DrJennSimmonsInstagram: https://www.instagram.com/drjennsimmons/YouTube: https://www.youtube.com/@dr.jennsimmons
The story of how tamoxifen went from a failed contraceptive pill, to being used to prevent and treat breast cancer around the world. It was the first ever targeted cancer drug. Laura Jones speaks to Professor V. Craig Jordan, who helped bring it to the world's attention in the 1970s.
Ripped from the pages of the popular Wildfire Magazine anthology, “Igniting the Fire Within,” we've curated this special mini podcast for you. Each Friday, hear a new bite-sized episode. Featuring “just the stories” from the book read by the authors. Think of this as your dynamic audiobook version of Igniting the Fire Within. Enjoy! This episode features Tamira Jubber reading her essay “Linda: My Hero, My Tamoxifen Tester.” Tamira is retired. Diagnosed at 29. IDC, Stage III, Triple Positive. Colorado Springs, CO. Buy the Wildfire book “Igniting the Fire Within: Stories of Healing, Hope & Humor, Inside Today's Young Breast Cancer Community”: https://www.amazon.com/dp/B0BJVJ629F?ref_=pe_3052080_397514860More about Tamira: https://www.instagram.com/meandher2neu/Hear Tamira's story followed by a conversation with April Stearns on The Burn: https://player.captivate.fm/episode/cd54b590-654e-493b-ab39-3fdddcf76f2cGet the free Wildfire email newsletter: https://www.wildfirecommunity.orgLearn about Wildfire writing workshops: https://www.wildfirecommunity.org/workshopsShop Wildfire merch & more: https://www.wildfirecommunity.org/shopSend your voice recording testimonial to editor@wildfirecommunity.org*Free* Get Wildfire and The Burn freebies here: https://www.wildfirecommunity.org/freehttps://www.wildfirecommunity.org/shopTamira Jubber Show NotesRelease date: Jun 2, 2023Title: ITFW: Linda: My Hero, My Tamoxifen Tester with Tamira JubberEpisode: E04 (Burn E99)Ripped from the pages of the popular Wildfire Magazine anthology, “Igniting the Fire Within,” we've curated this special mini podcast for you. Each Friday, hear a new bite-sized episode. Featuring “just the stories” from the book read by the authors. Think of this as your dynamic audiobook version of Igniting the Fire Within. Enjoy! This episode features Tamira Jubber reading her essay “Linda: My Hero, My Tamoxifen Tester.” Tamira is retired. Diagnosed at 29. IDC, Stage III, Triple Positive. Colorado Springs, CO. Buy the Wildfire book “Igniting the Fire Within: Stories of Healing, Hope & Humor, Inside Today's Young Breast Cancer Community”: https://www.amazon.com/dp/B0BJVJ629F?ref_=pe_3052080_397514860More about Tamira: https://www.instagram.com/meandher2neu/Hear Tamira's story followed by a conversation with April Stearns on The Burn:
Dr Sarah Ball and Dr Alison Macbeth discuss the challenges of endocrine treatment and the significant impact this has on the patients they see. They also answer some of our listeners' questions, such as the use of HRT with Tamoxifen and we discuss vaginal oestrogen whilst on Tamoxifen and vaginal oestrogen whilst on aromatase inhibitors.Dr Sarah Ball has a special interest in women with a past history of cancer and a history of Histamine Intolerance.Dr Alison MacBeth is a breast speciality doctor who has set up a menopause clinic within her NHS breast unit in Glasgow.They both work in a private practice too. Links are below.https://www.healthinmenopause.co.uk/about/team/dr-sarah-ballhttps://www.healthinmenopause.co.uk/about/team/dr-alison-macbethEpisode mentions:Episode 22: Antidepressants to Treat the Symptoms of Menopause after Cancer Episode 30: Rethinking Tamoxifen & Aromatase Inhibitors About Dani:The Menopause and Cancer Podcast is hosted by Dani Binnington, menopause guide, patients advocate for people in menopause after a cancer diagnosis, and founder of the online platform Healthy Whole Me. There is lots of information out there about the menopause but hardly any if you have had a cancer diagnosis as well. Many people say to me they have no idea what their options are, who to ask for help, and that they feel really isolated in their experiences. I started this podcast because there was nothing out there when I was thrown into surgical menopause at the age of 39, which followed on from my cancer diagnosis aged 33.Through the episodes, I want to create more awareness, share information from our fabulous guest experts, doctors and other specialists in the cancer and menopause field. And of course, I will share stories from the people in our community.So that together we can work towards a better menopause experience. For all of us.More educated, better informed and less alone.Connect with Dani:Instagram @healthywholeme Facebook: @healthywholeme Join Dani's private Facebook group: https://www.facebook.com/groups/menopauseandcancerchathubFor oodles of inspiration, healthy recipes, yoga classes and all round positivity go to her website: https://www.healthywholeme.com/
High Yield Breast Cancer Review.Review for your PANCE, PANRE, Eor's and other Physician Assistant exams. Merchandise Link: https://cram-the-pance.creator-spring.com/►Paypal Donation Link: https://bit.ly/3dxmTql (Thank you!)Included in review: Breast cancer risk factors, clinical manifestations, physical exam findings, screening, diagnostic tools including mammogram, ultrasound, fna, core needle biopsy, surgical biopsy, Paget disease of the breast, Inflammatory breast cancer, In situ, Invasive, Infiltrating ductal carcinoma, HER2 positive, hormone receptor positive, Tamoxifen, Trastuzumab, targeted therapy, chemotherapy, radiation.
In this episode, Dr. Amy is diving into the details of losing weight while on tamoxifen. Many cancer survivors have heard that tamoxifen causes weight gain. But what you might not know is that there is a science-backed way to maintain your weight on lose weight while on tamoxifen. Continue listening to find out how you can lose weight while taking this Tamoxifen. Get your FREE copy of 15 Simple Cancer Recovery Recipes >> www.cancerrecoveryrecipes.com
Both tamoxifen and aromatase inhibitors (AIs) are hormonal therapies used in the treatment of oestrogen-positive (ER-positive) breast cancers to stop tumour growth and recurrence and to treat cancer that has come back after initial treatment or that has spread to other parts of the body.These treatments come with the benefits of reducing the risks of cancer recurrence and they also come with a host of unwanted side effects. Many women say that being on a long-term anti-hormone treatment is much harder to navigate than chemotherapy, radiotherapy, and surgery altogether.In today's episode, I am inviting Dr Alison Macbeth into the conversation. She is a Breast Speciality Doctor in an NHS Breast Surgery in Glasgow and sees NHS patients from all over the west coast of Scotland.She is passionate about meeting the often-overlooked needs of women in all stages of treatment or recovery from breast cancer. She gained experience as an NHS GP with a special interest in Women's Health, Menopause and Genito-urinary prolapse.Alison has an incredible understanding of what women go through and brings a compassionate approach to helping them have a good quality of life after their cancer diagnosis. You can find Dr Alison Macbeth here https://thebms.org.uk/clinic/stobhill-hospital-breast-unit/About Dani:The Menopause and Cancer Podcast is hosted by Dani Binnington, menopause guide, patients advocate for people in menopause after a cancer diagnosis, and founder of the online platform Healthy Whole Me. There is lots of information out there about the menopause but hardly any if you have had a cancer diagnosis as well. Many people say to me they have no idea what their options are, who to ask for help, and that they feel really isolated in their experiences. I started this podcast because there was nothing out there when I was thrown into surgical menopause at the age of 39, which followed on from my cancer diagnosis aged 33.Through the episodes, I want to create more awareness, share information from our fabulous guest experts, doctors and other specialists in the cancer and menopause field. And of course, I will share stories from the people in our community.So that together we can work towards a better menopause experience. For all of us.More educated, better informed and less alone.Connect with Dani:Instagram @healthywholeme Facebook: @healthywholeme Join Dani's private Facebook group: https://www.facebook.com/groups/menopauseandcancerchathubFor oodles of inspiration, healthy recipes, yoga classes and all round positivity go to her website: https://www.healthywholeme.com/
In today's episode, I discuss how participating in a fasting protocol can be beneficial to breast cancer patients. Research has shown very promising results regarding using fasting to lower your risk of breast cancer recurrence and also to enhance the efficacy of chemotherapy treatments. I have utilized fasting in my life for decades for various reasons and have seen many benefits. Topics covered in this episode: 1. What is IF (intermittent fasting)? How do you do it? 2. Why is fasting good to prevent breast cancer from coming back? 3. How can fasting increase the benefits of chemotherapy treatment and reduce side effects? 4. Who shouldn't fast? 5. Common questions and concerns when starting a fasting protocol 6. How to make fasting easier 7. Why women who don't tolerate Tamoxifen should consider IF 8. My experimentation with fasting over the last 25 years Fasting has been studied as a potential way to improve chemotherapy outcomes. Short-term fasting has been observed to increase chemotherapy sensitivity in some cancer cells, enhance cancer cell death, and reduce chemotherapy-induced side effects. Fasting also increases the levels of certain hormones such as growth hormone, which may be beneficial for chemotherapy efficacy. In addition, fasting may reduce inflammation and oxidative stress, which are important factors in the effectiveness of chemotherapy. Finally, fasting may reset the body's metabolism, allowing it to better utilize chemotherapy drugs. As always, thank you for listening! Please subscribe to the podcast, and leave a positive review. It really helps get this information to the people who need and want it. Plus, I would be so grateful. If you are interested in working together to create a customized nutrition, stress management and potentially add a fasting protocol to support your body through any stage of the cancer journey, please reach out to me via my website: www.junibwell.com/contact Check out my free resources for breast cancer patients! Follow me on social media: Instagram: @junibwell Facebook: www.facebook.com/junibwell Check out my free guided meditation tracks.
Dr. Liz O'Riordan - – a breast surgeon with breast cancer. Her mission is to help cancer patients cope with life outside the hospital by showing health care professionals that it's the little things that matter. She co-wrote ‘The Complete Guide to Breast Cancer: How to Feel Empowered and Take Control', to help patients and their families as they go through treatment. She tells us her story. What do you wish people knew about breast cancer? Let's talk about controllable risk factors for breast cancer – Alcohol and adiposity Give us some frank advice about sex and relationships How to cope with the emotional burden of breast cancer Let's talk about self image The role of weight lifting and exercise How can the partners help? How does the sexual role change when care giving roles change? Talk about the collateral damage of breast cancer treatment could be thanks to an instant menopause and chronic pain. Vaginal atrophy on Anastrazole and Tamoxifen and chemo – options ACOG statement on use of Vag E in breast cancer pts. The Complete Guide to Breast Cancer: How to Feel empowered and take control https://amzn.to/37E1woz https://liz.oriordan.co.uk/ https://podcasts.apple.com/gb/podcast/don-t-ignore-the-elephant/id1588554895 https://www.instagram.com/oriordanliz/
Fill up with delicious practice-changing knowledge food from #SGIM22 as The Curbsiders team discusses breast cancer survivorship, sexual dysfunction, How climate change will affect health, Are PT consults necessary in the hospital?, Do we need antibiotics for aspiration events?, bias in note writing, Are plant-based meats a healthy?, complications after breast implantation, how to get breast reduction approved, doxycycline for chlamydia, the metronidazole and alcohol myth, pearls for clinician-educators, telehealth, TEACHIM.org, CGMs help lower a1c, PT for rotator cuff disease, Is it safe to taper antidepressants? and how to treat methamphetamine use disorder! Note: There is no CME for this episode, but claim CME for prior episodes at curbsiders.vcuhealth.org! Episodes | Subscribe | Spotify | Swag! | Top Picks | Mailing List | thecurbsiders@gmail.com | Free CME! Credits Written and Hosted by: Nora Taranto MD, Beth Garbitelli (about to be an MD!), Era Kryzhanovskaya MD, Justin Berk MD, MPH, MBA, Shreya Trivedi MD, Chris Chiu MD, Paul Williams MD, Matthew Watto MD Show Notes and Cover Art: Matthew Watto MD, FACP Showrunner: Matthew Watto MD, FACP Technical Production: Pod Paste Show Segments Intro A few ambulatory teaching models include the One Minute Preceptor, SNAPS (summarize, narrow, analyze, probe, plan, and select), PIPP (precepting in the presence of the patient) [see Community Preceptor Toolbox] Ikigai is a Japanese term indicating a motivational force or reason for living. It is associated with decreased mortality [Tanno, 2009]. Explore your ikigai here (PositivePsychology.com). Listening to podcasts while driving does not affect knowledge retention (Gottleib et al. 2021) Treatment of Hot flashes: Avoid paroxetine, fluoxetine, and sertraline in breast cancers survivors taking tamoxifen. Instead use venlafaxine (or another SNRI), citalopram, or escitalopram. Gabapentin given at bedtime is also an option. (Clinical Update 2019: Tamoxifen and Antidepressants) Distress in patients with cancer can be measured using the NCCN screening tool [NCCN Distress Thermometer] Don't forget to ask for a Cancer Survivorship Plan from oncology [CDC Cancer Survivorship Care Plans] Ask about sexual dysfunction in cancer survivors. How will climate change impact our patient's health? NIH framework; CH2OPD2 environmental screening tool [CH2OPD2 ]; and the 15 steps of climate communication. Use the AM-PAC score cutoff of >18 to avoid a PT consult in hospitalized patients (Martinez 2021). Early antibiotics after an aspiration event do not improve outcomes (Aga 2021). Biased language is more common in notes about Black patients (Beach 2021). Be thoughtful about what you write and role model good behavior. While plant-based meats are more eco-friendly than animal-sourced meats, they are heavily processed foods (van Vliet 2021) and may have high sodium. Silicone breast implant rupture can be insidious. Guidelines recommend screening with MRI after 6 years, then every 2-3 years (FDA 2020, More FDA info) (Note: FDA's most recent guidance also recommends ultrasound as an alternative screening method, so always check with the patient's insurance about which modality will be covered) Document a trial of NSAIDs, physical therapy, attempted weight loss, and supportive bra usage before breast reduction surgery for macromastia. Doxycycline is now first line for chlamydia rather than azithromycin [STI Treatment Guidelines Update], BUT the most effective treatment is the one your patient will take! Metronidazole does not cause a disulfiram-like reaction and is no longer recommended by the guidelines [STI Treatment Guidelines Update] More clinician-educator pearls from Era: Don't be afraid to brand yourself! Network with like-minded individuals (e.g. interest groups). BST mode: bite-sized teaching pearls can help reduce extrinsic load and improve retention [Manning, 2021] A guided discussion based on Scrubs episodes can improve resident wellness [Holtzclaw 2021] Chris recaps some posters (click links to see them on Twitter!): Telehealth disparities and tech equity (poster 1, poster 2); TeachIM.org (poster) Continuous glucose monitors can help lower a1c in patients on basal insulin [Martens 2021] A single session of PT improved shoulder pain. The benefits of steroid injections were limited to 8 weeks in the GRASP trial [Hopewell 2021] There is a high risk of recurrence after tapering antidepressants [Lewis 2021] Methamphetamine use disorder can be treated with IM naltrexone every 3 weeks, plus oral bupropion 450 mg daily [Trivedi 2021]. Limitations include cost and co-use of opioids. Outro Sponsor: Masterworks Get started at masterworks.art/curbsiders. Sponsor: Ten Thousand Get 15% off at tenthousand.cc/curb Sponsor: Green Chef Go to GreenChef.com/curb130 and use code curb130 to get $130 off, plus free shipping! Sponsor: Blueland Get 20% off your first order at blueland.com/curb