Podcasts about Tranexamic acid

In this popular episode, Dr. Talat Uppal, an obstetrician-gynecologist specialising in heavy menstrual bleeding, shares her expertise on a condition affecting one in four women yet rarely discussed openly. This eye-opening conversation sheds light on how women often normalise suffering through periods that drastically impact their quality of life.The discussion reveals shocking statistics: 25% of women experience heavy menstrual bleeding, yet more than half never seek medical help. Dr. Uppal provides clear indicators of abnormal bleeding – passing large clots, changing protection every 1-2 hours, waking at night to change, using multiple protection types simultaneously, and embarrassing "flooding" episodes. These symptoms can lead to iron deficiency, anaemia, and significant quality of life impacts.Learn about the spectrum of treatment options, from medications like Tranexamic Acid to the highly effective Mirena IUD and surgical interventions including endometrial ablation. She emphasises that most women find significant relief once properly treated, with many asking, "Why didn't I have this earlier? Why did I suffer so much?"Perhaps most powerful is the exploration of how heavy bleeding becomes normalised at multiple levels – by women themselves, healthcare providers who don't offer full treatment options, and society that suggests women should simply endure until menopause. This normalisation condemns many to years of unnecessary suffering when effective solutions exist.The conversation offers practical advice for women seeking help, emphasising the importance of advocating for yourself and being knowledgeable about available options. Have you been suffering in silence? This conversation might be the catalyst for transforming your quality of life. Listen, learn, and advocate for your menstrual health.ResourcesWomen's Health Road Clinic - websiteWomen's Health Road - InstagramWomen's Health Road - LinkedinThank you for listening to my show! Join the conversation on Instagram

Today, we're talking about the use of tranexamic acid or “TXA” for rotator cuff repair surgery. First, what is TXA? If you're not an arthroplasty surgeon or a traumatologist, you may not be as familiar with this medication. TXA is drug that inhibits the enzymatic breakdown of fibrin blood clots, also known as fibrinolysis. By doing this, TXA stabilizes the thrombi, or blood clots, and thus decreases bleeding. TXA was originally developed to treat postpartum hemorrhage but its use has evolved over the years. It is now often used perioperatively in the setting of elective surgery to reduce blood loss, blood transfusions, ecchymosis, and hematoma formation.In the field of orthopedics, use of TXA has traditionally been limited to big open surgeries where large volume blood loss is a concern, such as total joint replacement, fracture fixation and spine procedures. However, sports medicine procedures that rely extensively on visual clarity of the surgical field, such as knee and shoulder arthroscopy, can also greatly benefit from the use of TXA. By lessening intraoperative bleeding, TXA may result in better visualization of the surgical field, potentially decreasing operative time and subsequent postoperative swelling and pain. That is the clinical question that our paper today aimed to investigate. The article that we are reviewing is titled “Tranexamic Acid for Rotator Cuff Repair: A Systematic Review and Meta-analysis of Randomized Controlled Trials.” 

Show notes at pharmacyjoe.com/episode985. In this episode, I'll discuss the IV vs nebulized route for tranexamic acid to treat hemoptysis. The post 985: Is the IV or Nebulized Route Better When Giving Tranexamic Acid for Hemoptysis? appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode981. In this episode, I'll discuss tranexamic acid for controlling iatrogenic bleeding during flexible bronchoscopy. The post 981: Tranexamic Acid to Control Iatrogenic Bleeding During Flexible Bronchoscopy appeared first on Pharmacy Joe.

If you're an ASOPRS Member, Surgeon or Trainee and are interesting in hosting a podcast episode, please submit your idea by visiting: asoprs.memberclicks.net/podcast About the Hosts Daniel J. Ozzello, MD - Dr. Daniel J. Ozzello is a dedicated faculty member in the Division of Oculoplastics at the University of Colorado. With a rich background that includes training in ophthalmology at the Wills Eye Hospital and an ASOPRS fellowship in San Diego under the esteemed Dr. Don Kikkawa and Dr. Bobby Korn, Dr. Ozzello has established a diverse practice in oculoplastics as well as urgent and inpatient ophthalmic care. At Colorado, he engages in clinical care, research and teaching. Caroline Vloka, MD - Dr. Caroline Vloka recently completed her fellowship at the University of Colorado following her residency in Pittsburgh. Bringing fresh perspectives and insights, she has already made a substantial impact as a new faculty member. Her interests lie in advancing oculoplastic surgery techniques and patient outcomes, carrying forward her rigorous training and passion for patient care. Episode Summary: In this informative episode of the OculoFacial Podcast, Dr. Daniel J. Ozzello teams up with Dr. Caroline Vloka to delve into the latest advancements in oculoplastic surgery, focusing on two significant blepharoplasty studies. The discussion revolves around the effectiveness of tranexamic acid (TXA) in surgery, alongside an exploration of the cost-effectiveness of these surgical interventions and their impacts on patient care. Introducing listeners to these critical insights, the duo unpacks recent research findings, igniting conversations on how these might enhance surgical practices and patient outcomes. The analysis begins with an examination of a study concerning the preoperative use of TXA in eyelid surgery, meant to reduce bruising and improve patient satisfaction. Highlighting its potential benefits, Dr. Ozzello and Dr. Vloka weigh the simplicity and cost-effectiveness of incorporating TXA into regular surgical protocols. The conversation then shifts towards evaluating the economic and quality-of-life impacts that blepharoplasty offers. The pair discuss a study that aligns the procedure with high cost-effectiveness scores, emphasizing its beneficial role in elevating patient functioning and wellbeing. Key Takeaways: Tranexamic Acid Efficacy: Recent studies demonstrate that tranexamic acid significantly reduces bruising and enhances patient satisfaction in blepharoplasty procedures. Oculoplastics Cost-Effectiveness: Blepharoplasty is proven to be highly cost-effective, providing substantial improvements in quality of life for patients with dermatochalasis Importance of Context: The subjective nature of cosmetic and functional outcomes can vary based on demographic factors and patient profiles. Thorough Patient Education: Managing patient expectations about postoperative outcomes is crucial for satisfaction, especially when comparing with other surgeries like cataract interventions. Collaborative Inquiry: There is a call for larger-scale studies and collaborative data pooling in oculoplastic research to better address rare conditions like idiopathic orbital myositis Resources: University of Colorado - Division of Oculoplastics: Official Website Publications on Tranexamic Acid and Blepharoplasty: Recent articles in OPRS (Oculoplastic and Reconstructive Surgery). Listen to the full episode for valuable insights and stay tuned for more enlightening and engaging content from the OculoFacial Podcast!  

Description: Looking to stay ahead in the evolving world of skincare? We've got just the insights you need. This week, we're joined by Daniel Winn as we explore the advancements in bioavailable prodrugs and the expanding clinical skincare segment. Listen in as we dive into the science behind these innovations and what they mean for the future of consumer skincare. Each Thursday, join Dr. Raja and Dr. Hadar, board-certified dermatologists, as they share the latest evidence-based research in integrative dermatology. For access to CE/CME courses, become a member at LearnSkin.com.   Daniel Winn, PhD has spent several decades commercializing cosmetic ingredients for the global beauty industry. He's held a series of positions at global raw material companies where he led transformational efforts in green chemistry, and the development of new anti-microbial agents as safer & gentler preservatives for topical products. In 2018 he founded Actera Ingredients, a startup whose goal was to advance the science and efficacy of active agents for skincare and hair repair. Dan is the inventor or co-inventor of several patents, and has a PhD in Chemical Engineering from the University of Massachusetts Amherst.   Sponsored by Actera Visit Actera's website for more information. 

Melasma!Welcome back to another episode of Just Laser It, where we break down the science behind the most common skin conditions and discuss the latest in cosmetic dermatology. Today, we're diving into a particularly stubborn condition—melasma. Known for its characteristic dark patches, melasma can be incredibly frustrating to treat due to its complex triggers and chronic nature. While many of us may look to advanced treatments like lasers or chemical peels, topicals are actually the first line of defense and often the most effective way to manage this condition. In fact, relying too heavily on procedures may not always improve the appearance and, in some cases, can even make things worse. Join us to explore the challenges of treating melasma and why starting with the right topical regimen is critical to long-term success.Let's get started!Thank you for your listenership!

Show notes at pharmacyjoe.com/episode940. In this episode, I'll discuss whether tranexamic acid has a role in the treatment of aneurysmal subarachnoid hemorrhage. The post 940: Does Tranexamic Acid Have a Role In Aneurysmal Subarachnoid Hemorrhage? appeared first on Pharmacy Joe.

Send us a Text Message.In dieser Folge des JC geht es um eine Arbeit von Girardello et al. zur prähospitalen Gabe von Tranexamsäure bei Trauma. Mit im Studio dabei ist Konstantin Urbach, wissenschaftlicher Mitarbeiter der Klinik für Anästhesiologie am UKHDGirardello C, Carron P, Dami F, et al. Evaluation of the prehospital administration of tranexamic acid for injured patients: a state-wide observational study with sex and age-disaggregated analysis. Emergency Medicine Journal  Published Online First: 14 June 2024. doi: 10.1136/emermed-2023-213806

On today's show we cover lots of questions including…Does tranexamic acid really help reduce hyperpigmentation?Can Rene Furterer products for "reactional thinning hair" do what they claim?Will eating hyaluronic acid improve skin?What's the difference between derma glow versus hydra facial?Does Gucci Westman's use a more potent form of Vitamin C?What silicones or other materials are good replacements for cyclopentasiloxane?Beauty NewsCan omega-3 supplementation reduce acne severity?  Direct paper Neurocosmetics -  A new trend in skin careFive Ways to Ask a question -1. Send us a message through Patreon!2. You can record your question on your smart phone and email to thebeautybrains@gmail.com3. Send it to us via social media (see links below)4. Submit it through the following form - Ask a question5. Leave a voice mail message: 872-216-1856Social media accountson Instagram we're at thebeautybrains2018on Twitter, we're thebeautybrainsAnd we have a Facebook pageValerie's ingredient company - Simply IngredientsPerry's other website - Chemists CornerFollow the  Porch Kitty Krew instagram accountSupport the Show.

When tranexamic acid started gaining popularity a few years back, it felt similar to CBD. Suddenly it seemed like every brand was using it, but there didn't seem to be a lot of data shared on its effectiveness. In this episode, the chemists share the benefits that tranexamic acid can bring to skin, go through the testing (if any), and discuss whether or not it's a worthy addition to your skincare routine.

Topical Tranexamic Acid to Reduce Seizures in Cardiac Surgery

In this enlightening episode, Dr. Hack dives into the benefits of tranexamic acid for treating heavy menstrual bleeding (HMB). Join us as she shares her personal journey with this treatment and discusses how it might help others. Learn about the science behind tranexamic acid and why it's becoming a popular option for managing HMB. Tune in to learn more.

In this episode, Dr. David Bishop, a Specialist Anesthesiologist and Head of the Clinical Unit of Anaesthesia at Edendale Hospital in Pietermaritzburg talks about a vital topic and his recent publication, Tranexamic acid at cesarean delivery: drug-error deaths. Tranexamic acid at cesarean delivery: drug-error deaths https://pubmed.ncbi.nlm.nih.gov/36300729/ Spinal tranexamic acid – a new killer in town … Read More Read More

What is Flooding? What is tranexamic acid? What is a chromogenic essay? What is an MMB? What is the PBAC? And Who would be the douchiest of all douchebags? Answers to all this and more on January's FLOW with Jeanette Jones.   Jeanette Jones is a menstrual health advocate and a connoisseur in tracking for improved healthcare. Jeanette is passionate about empowering individuals to take control of their menstrual health experience. Her down-to-earth approach and wealth of knowledge make her a valuable resource for anyone looking to gain a deeper understanding of their menstrual cycle and improve their healthcare decisions.   FLOW is straight talk about extreme periods, with new episodes the second Thursday of each month. Tune in for tips for self study, shared discoveries and to expand menstrual awareness.    Program Notes:   Guest Info: Jeannette Jones  Jeanette Jones Linkedin: https://www.linkedin.com/in/jeanette-jones-ok Menstrual Tracking Logs: https://www.hemophiliafed.org/resource/menstruation-tracking/ Tranexamic Acid info: https://www.ncbi.nlm.nih.gov/books/NBK532909/   How's Your Flow? We wanna know (Calendly link): https://calendly.com/flowtalk/flow-talk-period-pain-stories   HOST: Jessica RIchmond Website: jrich.online IG, @jessicalaurenrichmond  Twitter @geniuspills    HOST: Sarah Watson Website: sarahwatsonlpc.com Podcast: Behind The Bedroom Door Facebook: @sarahwatsonlpcsextherapy IG @swsxtherapy Twitter @swsextherapy   FLOW is sponsored by Takeda, the manufacturer of a treatment for adults with von Willebrand disease. To see if this treatment might be right for you and your needs, visit: https://ssshare.it/2rnK    Connect with BloodStream Media: Find all of our bleeding disorders podcasts on  BloodStreamMedia.com BloodStream on Facebook  BloodStream on Twitter    Check out Believe Limited's Other Work: BloodFeed: bloodfeed.com Bombardier Blood: bombardierblood.com Hemophilia: The Musical: breakingthroughhemophilia.com My Beautiful Stutter: mybeautifulstutter.com/ Stop The Bleeding!: stbhemo.com Teen Impact Awards: teenimpactawards.com The Science Fair: thesciencefair.org  

Contributor: Kiersten Williams MD, Travis Barlock MD, Jeffrey Olson MS2 Summary: In this episode, Dr. Travis Barlock and Jeffrey Olson meet in the studio to discuss a clip from Dr. Williams' talk at the “Laboring Under Pressure, Managing Obstetric Emergencies in a Global Setting” event from May 2023. This event was hosted at the University of Denver and was organized with the help of Joe Parker as a fundraiser for the organization Health Outreach Latin America (HOLA). Dr. Kiersten Williams completed her OBGYN residency at Bay State Medical Center and practices as an Obstetric Hospitalist at Presbyterian/St. Luke's Medical Center in Denver, Colorado. During her talk, Dr. Williams walks the audience through the common causes and treatments for post-partum hemorrhage (PPH). Some important take-away points from this talk are: The most common causes of PPH can be remembered by the 4 T's. Tone (atony), Trauma, Tissue (retained placenta), and Thrombin (coagulopathies). AV malformations of the uterus are probably underdiagnosed. Quantitative blood loss is much more accurate than estimated blood loss (EBL). The ideal fibrinogen for an obstetric patient about to deliver is above 400 mg/dl - under 200 is certain to cause bleeding. Do not deliver oxytocin via IV push dose, it can cause significant hypotension. Tranexamic Acid is available in both IV and PO and can be administered in the field. The dose is 1 gram and can be run over 10 minutes if administered via IV. It is best if used within 3 hours of delivery. When performing a uterine massage, place one hand inside the vagina and one hand on the lower abdomen. Then rub the lower abdomen like mad. A new option for treating PPH is called the JADA System which is slimmer than a Bakri  Balloon and uses vacuum suction to help the uterus clamp down.* Another option for a small uterus is to insert a 60 cc Foley catheter. In an operating room, a B-Lynch suture can be put in place, uterine artery ligation can be performed, and as a last resort, a hysterectomy can be done. *EMM is not sponsored by JADA system or the Bakri balloon. References Andrikopoulou M, D'Alton ME. Postpartum hemorrhage: early identification challenges. Semin Perinatol. 2019 Feb;43(1):11-17. doi: 10.1053/j.semperi.2018.11.003. Epub 2018 Nov 14. PMID: 30503400. Committee on Practice Bulletins-Obstetrics. Practice Bulletin No. 183: Postpartum Hemorrhage. Obstet Gynecol. 2017 Oct;130(4):e168-e186. doi: 10.1097/AOG.0000000000002351. PMID: 28937571. Federspiel JJ, Eke AC, Eppes CS. Postpartum hemorrhage protocols and benchmarks: improving care through standardization. Am J Obstet Gynecol MFM. 2023 Feb;5(2S):100740. doi: 10.1016/j.ajogmf.2022.100740. Epub 2022 Sep 2. PMID: 36058518; PMCID: PMC9941009. Health Outreach for Latin America Foundation - HOLA Foundation. (n.d.). http://www.hola-foundation.org/ Kumaraswami S, Butwick A. Latest advances in postpartum hemorrhage management. Best Pract Res Clin Anaesthesiol. 2022 May;36(1):123-134. doi: 10.1016/j.bpa.2022.02.004. Epub 2022 Feb 24. PMID: 35659949. Pacheco LD, Saade GR, Hankins GDV. Medical management of postpartum hemorrhage: An update. Semin Perinatol. 2019 Feb;43(1):22-26. doi: 10.1053/j.semperi.2018.11.005. Epub 2018 Nov 14. PMID: 30503399. Produced by Jeffrey Olson, MS2 | Edited by Jeffrey Olson and Jorge Chalit, OMSII

Dr. Zach Cost and Dr. Tem Bendapudi join the show to discuss the literature pertaining to tranexamic acid and thromboembolic risk. Dr. Zach Cost is an anesthesia resident at the Massachusetts General Hospital. Dr. Pavan (“Tem”) Bendapudi holds a joint faculty appointment in the Division of Hematology and Blood Transfusion Service and is assistant professor of medicine at Harvard Medical School. This podcast was recorded as part of the Depth of Anesthesia podcast elective. Thanks for listening! If you enjoy our content, leave a 5-star review on Apple Podcasts and share our content with your colleagues. — Follow us on Instagram @DepthofAnesthesia and on Twitter (X) @DepthAnesthesia for podcast and literature updates. Email us at depthofanesthesia@gmail.com with episode ideas or if you'd like to join our team. Music by Stephen Campbell, MD. — References CRASH-2 trial collaborators; Shakur H, Roberts I, Bautista R, Caballero J, Coats T, Dewan Y, El-Sayed H, Gogichaishvili T, Gupta S, Herrera J, Hunt B, Iribhogbe P, Izurieta M, Khamis H, Komolafe E, Marrero MA, Mejía-Mantilla J, Miranda J, Morales C, Olaomi O, Olldashi F, Perel P, Peto R, Ramana PV, Ravi RR, Yutthakasemsunt S. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet. 2010 Jul 3;376(9734):23-32. doi: 10.1016/S0140-6736(10)60835-5. Epub 2010 Jun 14. PMID: 20554319. Henry DA, Carless PA, Moxey AJ, et al. Anti‐fibrinolytic use for minimising perioperative allogeneic blood transfusion. Cochrane Database of Systematic Reviews. 2011;(1). doi:10.1002/14651858.CD001886.pub3 Ker K, Edwards P, Perel P, Shakur H, Roberts I. Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis. BMJ. 2012;344:e3054. doi:10.1136/bmj.e3054 Myles PS, Smith JA, Forbes A, et al. Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery. New England Journal of Medicine. 2017;376(2):136-148. doi:10.1056/NEJMoa1606424 Devereaux PJ, Marcucci M, Painter TW, et al. Tranexamic Acid in Patients Undergoing Noncardiac Surgery. New England Journal of Medicine. 2022;386(21):1986-1997. doi:10.1056/NEJMoa2201171 POISE 3 PeriOperative ISchemic Evaluation-3 (POISE-3) study Shakur H, Roberts I, Fawole B, et al. Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum hemorrhage (WOMAN): an international, randomized, double-blind, placebo-controlled trial. The Lancet. 2017;389(10084):2105-2116. doi:10.1016/S0140-6736(17)30638-4 Roberts I, Shakur-Still H, Afolabi A, et al. Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. The Lancet. 2020;395(10241):1927-1936. doi:10.1016/S0140-6736(20)30848-5 Taeuber I, Weibel S, Herrmann E, et al. Association of Intravenous Tranexamic Acid With Thromboembolic Events and Mortality: A Systematic Review, Meta-analysis, and Meta-regression. JAMA Surgery. 2021;156(6):e210884. doi:10.1001/jamasurg.2021.0884

Host Dr. Malcolm DeBaun interviews paper author Dr. Brandon Yuan. This paper was presented at the 2023 OTA Annual Meeting.  To view the abstract while listening, download the free ConveyMED App: Apple Store click here Google Play click here. For additional educational resources visit https://ota.org/ 

Host Dr. Jacqueline Dunahoe interviews paper author Dr. Stephen Davis. This paper was presented at the 2023 OTA Annual Meeting. To see the abstract while listening, download the free ConveyMED App: Apple Store click here Google Play click here  For additional educational resources visit https://ota.org/

In episode 553, James and Mike get Jen Potter back to talk about the last option we have for heavy menstrual bleeding – tranexamic acid. We talk about how it compares to placebo, NSAIDs, progestins and levonorgestrel intrauterine devices and go over all the numbers for benefits and harms. And then as always, we put […]

Contributor: Aaron Lessen MD Educational Pearls: Tranexamic acid (TXA) is a common medication to achieve hemostasis in a variety of conditions Patients visiting the ED for gross hematuria (between March 2022 and September 2022) were treated with intravesical TXA 1 g tranexamic acid in 100 mL NS via Foley catheter Clamped Foley for 15 minutes Subsequent continuous bladder irrigation, as is standard in most EDs Compared with a cohort of patients visiting the ED for a similar concern between March 2021 and September 2021, the TXA patients had: A shorter median length of stay in the ED (274 min vs. 411 mins, P < 0.001). A shorter median duration of Foley catheter placement (145 min vs. 308 mins, P < 0.001) Fewer revisits after ED discharge (2.3% vs. 12.3%, P = 0.031) References 1. Choi H, Kim DW, Jung E, et al. Impact of intravesical administration of tranexamic acid on gross hematuria in the emergency department: A before-and-after study. Am J Emerg Med. 2023;68:68-72. doi:10.1016/j.ajem.2023.03.020 Summarized by Jorge Chalit, OMSII | Edited by Meg Joyce & Jorge Chalit, OMSII

On Episode 32 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the September 2023 issue of Stroke: “Prestroke and Poststroke Sulfonylurea Exposure and Functional Outcomes: A Post Hoc Analysis of the SHINE Trial” and “Sleep Duration Is Associated With Subclinical Carotid Plaque Burden.” She also interviews Dr. Alexandros Polymeris and Prof. Philippe Lyrer about their article “Tranexamic Acid for Intracerebral Hemorrhage in Patients on Non-Vitamin K Antagonist Oral Anticoagulants (TICH-NOAC): A Multicenter, Randomized, Placebo-Controlled, Phase 2 Trial.” For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20230829.123365

Hi Everyone, "Three minutes after the administration on the spinal anaesthetic they became restless and complained of severe pain in both lower limbs and back. Their heart rate and blood pressure increased to 130bpm and 160/100 mmHg. A rapid survey of previously administered medications revealed tranexamic acid 300mg was accidentally injected into the subarachnoid space instead of 15mg of hyperbaric bupivacaine." - case report 2021 Graeme and I sit down to do a deep dive on the serious topic of accidental neuraxial administration of tranexamic acid which may have up to 50% mortality. We discuss two papers which summarise over 40 published case reports of spinal administration and one case report of accidental epidural administration. Join us as we discuss the pharmacological mechanism of toxicity, proposed treatments and methods to minimise the risk of this occurring in the first place. References Catastrophic drug errors involving tranexamic acid administered during spinal anaesthesia. S. Patel, B. Robertson, I. McConachie Anaesthesia. 2019 Jul;74(7):904-914. - Open access Tranexamic acid-associated intrathecal toxicity during spinal anaesthesia: A narrative review of 22 recent reports. S. Patel Eur J Anesthesiol 2023 May 1;40(5):334-342. - This article is not open access. Accidental administration of tranexamic acid into the epidural space: a case report. C. Pysyk, L Filteau Can J Anaesth 69, pages 1169–1173 (2022) - open access Tranexamic acid-associated seizures: Causes and treatment. I.Lecker et al. Ann Neurol 2016 Jan;79(1):18-26.

Russell Gruen, Brian Burns and Stephen Bernard present the results of the PATCH-Trauma trial, investigating tranexamic acid in severe trauma. An independent editorial is delivered by Karim Brohi (London). Caroline Leech (Coventry) chairs a panel discussion consisting of Susan Rowell (Chicago), Carol Hodgson (Melbourne), John Holcomb (Birmingham, USA) and John Norrie (Edinburgh).

Show notes at pharmacyjoe.com/episode821. In this episode, I'll discuss the dose of inhaled tranexamic acid used for nonmassive hemoptysis. The post 821: What dose of inhaled tranexamic acid is used for nonmassive hemoptysis? appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode821. In this episode, I ll discuss the dose of inhaled tranexamic acid used for nonmassive hemoptysis. The post 821: What dose of inhaled tranexamic acid is used for nonmassive hemoptysis? appeared first on Pharmacy Joe.

CHEST May 2023, Volume 163, Issue 5 Prakash Ranjan Mishra, MBBS, MD, joins CHEST Podcast Moderator, Alice Gallo de Moraes, MD, to discuss whether the nebulized route of TA administration reduces the amount of hemoptysis compared with the IV route in patients presenting to the ED with hemoptysis. DOI:https://doi.org/10.1016/j.chest.2022.11.021   Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine.

Skincare is complex, especially when it comes to caring for your natural complexion! While some products may fail to deliver results, others can use harmful ingredients that damage the skin. However, using science-backed skincare knowledge, you can identify which formulations contain safe ingredients to brighten and nurture your beautiful skin.The Skin Report is a podcast created to educate listeners on methods to improve skin health for people of all ethnicities and ages. On this episode, host Dr. Sethi explains how specific skincare ingredients can safely improve skin health while producing brightened results. She describes how ingredients like Retinol, Vitamin C, Tranexamic Acid, Niacinamide, and Azelaic Acid can be incorporated within skincare to provide skin-brightening effects for a beautiful glowing complexion. In addition, she reviews some of the top recommended products on Amazon with these ingredients and gives listeners the inside scoop on which are safe and effective.Follow and DM a question for Dr. Sethi to answer on The Skin Report Podcast: RenewMD Beauty Instagram:https://www.instagram.com/renewmd_beauty/RenewMD Beauty Medical Spas, California:https://renewmdwellness.com/The Skin Report Season 1 Episode 32: Retinol:https://theskinreportbydrsethi.com/season-1-episode-32-retinol/

Date: March 3, 2023 Reference: Hosseinialhashemi et al. Intranasal Topical Application of Tranexamic Acid in Atraumatic Anterior Epistaxis: A Double-Blind Randomized Clinical Trial. Ann Emerg Med. 2022 Guest Skeptic: Dr. Dominique Trudel is a CCFP-EM resident in Ottawa, Ontario. Her interest is serving French minority communities delivering care at the Montfort Hospital in Ottawa. Case: Jim is […] The post SGEM#395: Too Much Blood from My Nose – Will TXA Help? first appeared on The Skeptics Guide to Emergency Medicine.

In today's VETgirl online veterinary continuing education podcast, we interview Dr. Morgan Kelley, DACVECC on her paper "Retrospective analysis of the use of tranexamic acid in critically ill dogs and cats (2018-;2019): 266 dogs and 28 cats." If you're not sure what tranexamic acid (TXA) is and how it works to stop bleeding, you want to tune in! Learn how TXA has been used in veterinary versus human medicine, what the indications or contraindications for it are in veterinary medicine, how you can administer it, and how you can use TXA in your day to day practice! Today's VETgirl podcast is sponsored by Merck Animal Health, makers of Nobivac® Intra-Trac® Oral BbPi, the first oral Bordetella bronchiseptica and canine parainfluenza virus vaccine with patented Immuno-Mist-R™ technology.

In episode 529, Mike and James welcome Mike Kolber back to the podcast and we discuss all the best available around the use of tranexamic acid for acute adult trauma and acute GI bleed. It seems to have an effect in one of these. Tune in to find out the numbers. Show Notes 1) Tools […]

Show notes at pharmacyjoe.com/episode772. In this episode, I'll discuss the IV vs nebulized route for tranexamic acid to treat hemoptysis. The post 772: What is the best route to give tranexamic acid for hemoptysis - IV or nebulizer? appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode772. In this episode, I ll discuss the IV vs nebulized route for tranexamic acid to treat hemoptysis. The post 772: What is the best route to give tranexamic acid for hemoptysis IV or nebulizer? appeared first on Pharmacy Joe.

Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast! This week, Drs. John and Mike Fralick discuss two recent papers – one, exploring the use of IVIG in the treatment of dermatomyositis, and the second investigating the effect of a tranexamic acid infusion in patients with acute gastrointestinal bleeding. ... The post Episode 52 – IVIG in Dermatomyositis and Tranexamic Acid in GI Bleeding first appeared on Healthy Debate. The post Episode 52 – IVIG in Dermatomyositis and Tranexamic Acid in GI Bleeding appeared first on Healthy Debate.

Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast! This week, Drs. John and Mike Fralick discuss two recent papers – one, exploring the use of IVIG in the treatment of dermatomyositis, and the second investigating the effect of a tranexamic acid infusion in patients with acute gastrointestinal bleeding. ...The post Episode 52 – IVIG in Dermatomyositis and Tranexamic Acid in GI Bleeding appeared first on Healthy Debate.

Show notes at pharmacyjoe.com/episode760. In this episode, I'll discuss tranexamic acid for controlling iatrogenic bleeding during flexible bronchoscopy. The post 760: Can You Use Tranexamic Acid For Controlling Iatrogenic Bleeding During Flexible Bronchoscopy? appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode760. In this episode, I ll discuss tranexamic acid for controlling iatrogenic bleeding during flexible bronchoscopy. The post 760: Can You Use Tranexamic Acid For Controlling Iatrogenic Bleeding During Flexible Bronchoscopy? appeared first on Pharmacy Joe.

Should you be asking for TXA (Tranexamic acid) in your cosmetic surgery procedure? If you asked plastic surgeons 5 years ago if they used TXA- nearly all of them would have said no.Originally approved for heavy menstrual bleeding and tooth extraction in hemophiliacs, TXA has been used off-label in cardiac, orthopedic and many other types of surgery. Recently TXA has made its way to plastic surgery, where surgeons are reportedly using it for nearly every aesthetic plastic surgical procedure - facelifts, liposuction, tummy tucks, breast lifts, and more.Does it really reduce bleeding, swelling and increase speed of recovery? Dr. Sam Rhee @bergencosmetic, Dr. Salvatore Pacella @sandiegoplasticsurgeon and Dr. Sam Jejurikar @samjejurikar discuss TXA, how and why they use it, and whether it really is a "WONDER DRUG" for cosmetic plastic surgery. Find out more at https://3plasticsurgerypodcast.com/---⁠#podcast #plasticsurgery #cosmeticsurgery #plasticsurgeon #beauty #boardcertified #aesthetic #3plasticsurgeonsandamicrophone ⁠#bergencosmetic ⁠#bestplasticsurgeon #beforeafter #aesthetics #realpatientrealresult #boardcertifiedplasticsurgeon #njplasticsurgeon #njplasticsurgery #nyplasticsurgeon #nyplasticsurgery 

Join us after hours at Dr. Bryan A. Cotton's pop-up bourbon bar at the AAST 2022 Meeting in Chicago. In this FANTASTIC & FUN episode, we talk amongst friends about cutting edge research at this year's meeting. To no one's surprise, coagulopathy, damage control resuscitation, whole blood, and factor replacement therapy just happen to be but a few of the topics discussed on Rounds.Time Stamps:00:12 AAST 2022 - Intro00:42 Sex diamoprhisms in coagulation01:52 Hemostatic profiles of female donors02:48 Pediatric whole blood (WB) is safe03:10 WB for TBI03:31 Leukoreduction is unnecessary05:30 TXA, TEG  and trauma06:44 STAAMP trial07:21 TXA: go early, big or go home07:52 Calcium...early!09:33 Canadian perspective on TXA and TEG – Neil Perry from London, ON11:25 Nori Bradley from Edmonton, AB13:53 Jordan Weinberg, not Canadian – Phoenix, AZ16:12 Issues with WB – COMBAT vs PAMPer17:31 Cold stored platelets18:22 Rapid transfusers and whole blood: Only the strong survive!!19:42 How are we doing with our resuscitation? 1:1:1 is just the beginning, not the end!21:44 Timing is everything!23:38 Plasma first resuscitation: “…God damn good!” -BAC24:37 Dr. Joshua B. Brown - Pittsburgh, PA25:31 More Canadian perspectives with Perry and Bradley29:48 Less is best!31:27 Prothrombin complex concentrate: Yay or nay?32:18 More on the endotheliopathy of trauma33:38 Just messing around and having a blast34:22 What was the best bourbon tonight?References:CRASH-2 trial collaborators, Shakur H, Roberts I, Bautista R, Caballero J, Coats T, Dewan Y, El-Sayed H, Gogichaishvili T, Gupta S, Herrera J, Hunt B, Iribhogbe P, Izurieta M, Khamis H, Komolafe E, Marrero MA, Mejía-Mantilla J, Miranda J, Morales C, Olaomi O, Olldashi F, Perel P, Peto R, Ramana PV, Ravi RR, Yutthakasemsunt S. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet. 2010 Jul 3;376(9734):23-32. doi: 10.1016/S0140-6736(10)60835-5. Epub 2010 Jun 14. PMID: 20554319.Gruen DS, Guyette FX, Brown JB, Okonkwo DO, Puccio AM, Campwala IK, Tessmer MT, Daley BJ, Miller RS, Harbrecht BG, Claridge JA, Phelan HA, Neal MD, Zuckerbraun BS, Yazer MH, Billiar TR, Sperry JL. Association of Prehospital Plasma With Survival in Patients With Traumatic Brain Injury: A Secondary Analysis of the PAMPer Cluster Randomized Clinical Trial. JAMA Netw Open. 2020 Oct 1;3(10):e2016869. doi: 10.1001/jamanetworkopen.2020.16869. PMID: 33057642; PMCID: PMC7563075.Guyette FX, Brown JB, Zenati MS, Early-Young BJ, Adams PW, Eastridge BJ, Nirula R, Vercruysse GA, O'Keeffe T, Joseph B, Alarcon LH, Callaway CW, Zuckerbraun BS, Neal MD, Forsythe RM, Rosengart MR, Billiar TR, Yealy DM, Peitzman AB, Sperry JL; STAAMP Study Group. Tranexamic Acid During Prehospital Transport in Patients at Risk for Hemorrhage After Injury: A Double-blind, Placebo-Controlled, Randomized Clinical Trial. JAMA Surg. 2020 Oct 5;156(1):11–20. doi: 10.1001/jamasurg.2020.4350. Epub ahead of print. Erratum in: JAMA Surg. 2021 Jan 1;156(1):105. PMID: 33016996; PMCID: PMC7536625.Moore HB, Moore EE, Chapman MP, McVaney K, Bryskiewicz G, Blechar R, Chin T, Burlew CC, Pieracci F, West FB, Fleming CD, Ghasabyan A, Chandler J, Silliman CC, Banerjee A, Sauaia A. Plasma-first resuscitation to treat haemorrhagic shock during emergency ground transportation in an urban area: a randomised trial. Lancet. 2018 Jul 28;392(10144):283-291. doi: 10.1016/S0140-6736(18)31553-8. Epub 2018 Jul 20. PMID: 30032977; PMCID: PMC6284829.Pusateri AE, Moore EE, Moore HB, Le TD, Guyette FX, Chapman MP, Sauaia A, Ghasabyan A, Chandler J, McVaney K, Brown JB, Daley BJ, MSupport the show

First, there was Episode 31: TXA for Epistaxis (the Zahed RCT from Tehran), then there was Episode 40: TXA for Epistaxis, Part Deux (the NoPAC trial), now there's Episode 64: TXA for Epistaxis, Part Trois, another Iranian RCT. So... we have conflicted evidence, all from RCTs, about whether TXA works for epistaxis. Dr. Jarvis goes through the prior trials and then gives a more detailed look at the new evidence. He closes by talking about how he handles conflicting evidence. Citation: Hosseinialhashemi M, Jahangiri R, Faramarzi A, et al. Intranasal Topical Application of Tranexamic Acid in Atraumatic Anterior Epistaxis: A Double-Blind Randomized Clinical Trial. Annals of Emergency Medicine. 2022;80(3):182-188. doi:10.1016/j.annemergmed.2022.04.010See omnystudio.com/listener for privacy information.

Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast! This week, podcast guests Dr. Emily Hughes and Dr. Justin Boyle discuss two recent papers – one, exploring the use of tranexamic acid in preventing perioperative bleeding in non-cardiac surgery, and the second investigating the relationship between socioeconomic status and ... The post Episode 44 – Tranexamic Acid in Non-Cardiac Surgery and Post-ICU Syndrome appeared first on Healthy Debate.

Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast! This week, podcast guests Dr. Emily Hughes and Dr. Justin Boyle discuss two recent papers – one, exploring the use of tranexamic acid in preventing perioperative bleeding in non-cardiac surgery, and the second investigating the relationship between socioeconomic status and ...The post Episode 44 – Tranexamic Acid in Non-Cardiac Surgery and Post-ICU Syndrome appeared first on Healthy Debate.

Show notes at pharmacyjoe.com/episode734. In this episode, I'll discuss whether the manner of tranexamic acid application changes the effectiveness for epistaxis. The post 734: Does the manner of tranexamic acid application change the effectiveness for epistaxis? appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode734. In this episode, I ll discuss whether the manner of tranexamic acid application changes the effectiveness for epistaxis. The post 734: Does the manner of tranexamic acid application change the effectiveness for epistaxis? appeared first on Pharmacy Joe.

Editor's Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief of JAMA, the Journal of the American Medical Association, for the July 26, 2022 issue.

The post The Utilization of Tranexamic Acid in Trauma Patients by Ruben Santiago, PharmD appeared first on The Pharm So Hard Podcast.

ACC Recap: John Mandrola, MD, provides part 1 of an ACC recap in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I – HTN in Pregnancy - Hypertension Control During Pregnancy Validated in Large Trial https://www.medscape.com/viewarticle/971486 - Treatment for Mild Chronic Hypertension during Pregnancy https://www.nejm.org/doi/full/10.1056/NEJMoa2201295 II – Prevention of Bleeding in Non-Cardiac Surgery - POISE-3 Backs Wider Use of Tranexamic Acid in Noncardiac Surgery https://www.medscape.com/viewarticle/971483 - Tranexamic Acid in Patients Undergoing Noncardiac Surgery https://www.nejm.org/doi/full/10.1056/NEJMoa2201171 III – HCM - VALOR-HCM: Novel Drug May Delay, Avert Invasive Therapy in OHCM https://www.medscape.com/viewarticle/971484 IV – Left Atrial Appendage Occlusion - Small Leaks After LAAO Linked to Thromboembolism, Bleeding https://www.medscape.com/viewarticle/971709 V – Low Sodium Diet for HF - Low-Sodium Diet Did Not Cut Clinical Events in Heart Failure Trial https://www.medscape.com/viewarticle/971482 - Reduction of dietary sodium to less than 100 mmol in heart failure (SODIUM-HF): an international, open-label, randomised, controlled trial https://doi.org/10.1016/S0140-6736(22)00369-5 VI – Flu Vaccine and Heart Failure - Flu Vaccines Cut Seasonal Death in Patients With Heart Failure https://www.medscape.com/viewarticle/971619 VII – New Anticoagulant? - Less Bleeding With Factor XI Inhibitor Anticoagulant? PACIFIC-AF https://www.medscape.com/viewarticle/971702 Features: - Sodium Restriction in Heart Failure: Another Dogma Felled by Randomization https://www.medscape.com/viewarticle/971697 - Percutaneous Left Atrial Appendage Occlusion: ACC Data Challenge Promise vs Reality https://www.medscape.com/viewarticle/971512 - Mavacamten in Hypertrophic Cardiomyopathy: Reasons for Both Optimism and Caution https://www.medscape.com/viewarticle/971485 You may also like: Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine https://www.medscape.com/features/public/machine The Bob Harrington Show with Stanford University Chair of Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact: news@medscape.net

Show notes at pharmacyjoe.com/episode698. In this episode, I'll discuss whether tranexamic acid has a role in the treatment of aneurysmal subarachnoid hemorrhage. The post 698: Does Tranexamic Acid Have a Role In Aneurysmal Subarachnoid Hemorrhage? appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode698. In this episode, I ll discuss whether tranexamic acid has a role in the treatment of aneurysmal subarachnoid hemorrhage. The post 698: Does Tranexamic Acid Have a Role In Aneurysmal Subarachnoid Hemorrhage? appeared first on Pharmacy Joe.