Podcasts about cochrane database

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Best podcasts about cochrane database

Latest podcast episodes about cochrane database

GeriPal - A Geriatrics and Palliative Care Podcast
Gabapentinoids - Gabapentin and Pregabalin: Tasce Bongiovanni, Donovan Maust and Nisha Iyer

GeriPal - A Geriatrics and Palliative Care Podcast

Play Episode Listen Later Mar 2, 2023 48:03


Gabapentin is the 10th most prescribed drug in the United States and use is increasing.  In 2002, 1% of adults were taking gabapentinoids (gabapentin and or pregabalin).  By 2015 that number increased to 4% of US adults. There are a lot of reasons that may explain the massive increase in use of these drugs.  One thing is clear, it is not because people are using it for FDA approved indications.  The FDA-approved indications for gabapentin are only for treating patients with partial seizures or postherpetic neuralgia. However, most gabapentin prescriptions are written off-label indications. On today's podcast we talk all about the Gabapentinoids - Gabapentin and Pregabalin - with Tasce Bongiovanni, Donovan Maust and Nisha Iyer.   It's a big episode covering a lot of topics. First, Nisha, a pain and palliative care pharmacist, starts us off with discussing the pharmacology of gabapentin and pregabalin, including common myths like they work on the GABA system (which is weird given the name of the drug).   Tasce, a surgeon and researcher, reviews the use of gabapentin in the perioperative setting and the research she had done on the prolonged use of newly prescribed gabapentin after surgery (More than one-fifth of older adults prescribed gabapentin postoperatively continue to take it more than 3 months later).  Donovan discusses the growth of “mood stabilizers/antiepileptics” (e.g. valproic acid and gabapentin), in nursing homes, particularly patients with Alzheimer's disease and related dementias. This includes a JAGS study recently published in 2022 showing that we seem to be substituting one bad drug (antipsychotics and opioids) with another bad drug (valproic acid and gabapentin). Lastly, we also addressed a big reason for the massive uptake of gabapentinoids: an intentional and illegal strategy by the makers of these drugs to promote off-label use by doing things like creating low-quality, industry-funded studies designed to exaggerate the perceived analgesic effects of these drug.  This long and sordid history of gabapentin and pregabalin is beautifully described in Seth Landefeld and Mike Steinman 2009 NEJM editorial. I could go on and on, but listen to the podcast instead and for a deeper dive, take a look at the following articles and studies: Gabapentin in the Perioperative setting: Prolonged use of newly prescribed gabapentin after surgery. J Am Geriatr Soc. 2022 Perioperative Gabapentin Use in Older AdultsRevisiting Multimodal Pain Management JAMA IM. 2022 Effect of Perioperative Gabapentin on Postoperative Pain Resolution and Opioid Cessation in a Mixed Surgical Cohort.  JAMA Surgery 2018 Gabapentin and mood stabilizers in the Nursing Home Setting: Antiepileptic prescribing to persons living with dementia residing in nursing homes: A tale of two indications. JAGS 2022 Trends in Antipsychotic and Mood Stabilizer Prescribing in Long-Term Care in the U.S.: 2011-2014 JAMDA 2020 Efficacy of Gabapentinoids: Gabapentinoids for Pain: Potential Unintended Consequences. AFP 2019 Gabapentin for chronic neuropathic pain in adults. Cochrane Database of Systematic Reviews Review. 2017 The Illegal Marketing Practices by Pharma promoting ineffective: The Neurontin Legacy — Marketing through Misinformation and Manipulation NEJM 2009 Narrative review: the promotion of gabapentin: an analysis of internal industry documents. Annals of IM. 2006  

Evidence Based Birth®
Replay - EBB 166 The Experience of a Powerful and Miraculous Birth with Brooklynn and Hoang Pham

Evidence Based Birth®

Play Episode Listen Later Jan 18, 2023 58:34


Today, I am excited to share a replay of one of my favorite birth stories featured on the Evidence Based Birth® podcast. EBB childbirth class graduates, Brooklyn and Hoang Pham, share their power and miraculous birth story, which became an instant classic and truly touched my heart.   As a content warning, we talk about the significantly high rates of maternal mortality among Black and Brown individuals and racism in birth work.  On today's podcast, we will be talking with Brooklynn and Hoang Pham. Brooklynn and Hoang currently live in Davis, California, and are the parents to Marvel, who turned seven months last December. Brooklynn is the senior managing director of Teach For America in Sacramento, and Hoang is finishing up his final year of law school at UC Davis School of Law. They took the Evidence Based Birth® Childbirth class with EBB instructor, Shalin Butterworth, and are here to share their birth story. We will talk about Brooklynn's and Hoang's empowering experience when they attended the Evidence Based Birth® Childbirth class and how it prepared them to feel ready for their powerful and miraculous birth with their doula and EBB instructor, Shalin.  Resources:  Sign up for the EBB Newsletter here.  Learn more about the EBB Instructor program here and find an instructor or course here.  Hoang and Brooklyn's YouTube: https://www.youtube.com/channel/UCOBNp5cuEQpBDY3-3Bnl6eQ/ Instagram: @_hoangpham Twitter: @_hoangpham Birthplace Lab: You can explore the maps at https://www.birthplacelab.org/maps/. There is a How To video with tips on using the interactive maps: https://www.birthplacelab.org/how-to-explore-the-maps/. Visit BirthPlaceLab.org to learn about your state's score! Research References: Balde, M. D., Nasiri, K., Mehrtash, H., et al. (2020). Labour companionship and women's experiences of mistreatment during childbirth: results from a multi-country community-based survey. BMJ Glob Health. 2020 Nov;5(Suppl 2):e003564. Click here.   Bohren, M. A., Berger, B. O., Munthe-Kaas, H., et al. (2019). Perceptions and experiences of labour companionship: a qualitative evidence synthesis. Cochrane Database of Systematic Reviews 2019, Issue 3. Art. No.: CD012449. Click here.   Bohren, M. A., Hofmeyr, G. J., Sakala, C., et al. (2017). Continuous support for women during childbirth. Cochrane Database Syst Rev. 2017 Jul 6;7(7):CD003766. Click here.   Vedam, S., Stoll, K., MacDorman, M., et al. (2018). Mapping integration of midwives across the United States: Impact on access, equity, and outcomes. PLoS One. 2018 Feb 21;13(2):e0192523. Click here. Go to our YouTube channel to see video versions of the episode listed above!! For more information and news about Evidence Based Birth®, visit www.ebbirth.com. Find us on:  TikTok Instagram Pinterest Ready to get involved?  Check out our Professional membership (including scholarship options) here  Find an EBB Instructor here  Click here to learn more about the Evidence Based Birth® Childbirth Class.

Psychiatry.dev -  All Abstracts TTS
Non-pharmacological interventions for sleep disturbances in people with dementia – PubMed

Psychiatry.dev - All Abstracts TTS

Play Episode Listen Later Jan 4, 2023


https://psychiatry.dev/wp-content/uploads/speaker/post-11364.mp3?cb=1672836057.mp3 Playback speed: 0.8x 1x 1.3x 1.6x 2x Download: Non-pharmacological interventions for sleep disturbances in people with dementia – PubMed Review Denise Wilfling et al. Cochrane Database of Systematic Reviews. 2023.Full EntryNon-pharmacological interventions for sleep disturbances in people with dementia – PubMed

UltraSounds
Postpartum Hemorrhage

UltraSounds

Play Episode Listen Later Nov 28, 2022 33:24


Survey: https://bit.ly/feedback_UltraSounds Theresa and Rachel discuss postpartum hemorrhage with Dr. Luke Burns. 00:30 Dr. Burns Biography 01:50 Case 1: 35 year old G4P4 with polyhydramnios, boggy uterus 09:17 Case 2: 35 year old G4P4 with postpartum hemorrhage and chronic hypertension 16:53 Case 3: hemodynamically unstable 35 year old G4P4 with postpartum hemorrhage 23:59 Case 4: 35 year old G4P4 with no return of menstruation Transcript: https://bit.ly/Ultrasounds_PPH Trends in maternal mortality: 2000 to 2017: estimates by WHO, UNICEF, UNFPA, World Bank Group and the United Nations Population Division. Geneva: World Health Organization; 2019. ACOG Practice Bulletin No. 183: Postpartum Hemorrhage. Obstet Gynecol 2017, 30(4). Wormer KC, Jamil RT, Bryant SB. Acute Postpartum Hemorrhage. StatPearls Publishing; 2022 Jan. ACOG Committee Opinion No. 794: Quantitative blood loss in obstetric hemorrhage. American College of Obstetricians and Gynecologists. Obstet Gynecol 2019;134. Bell, S. F., et al (2020). Incidence of postpartum haemorrhage defined by quantitative blood loss measurement: a national cohort. BMC pregnancy and childbirth, 20(1), 271. Parry Smith WR, et al. Uterotonic agents for first‐line treatment of postpartum haemorrhage: a network meta‐analysis. Cochrane Database of Systematic Reviews 2020, Issue 11. Vogel JP, et al. WHO recommendations on uterotonics for postpartum haemorrhage prevention: what works, and which one? BMJ Global Health 2019. A. Borovac-Pinheiro, et al. (2018). Postpartum hemorrhage: new insights for definition and diagnosis. American Journal of Obstetrics and Gynecology, 219(2):162-8. A. Leleu, et al. (2021). Intrauterine balloon tamponade in the management of severe postpartum haemorrhage after vaginal delivery: Is the failure early predictable?. European Journal of Obstetrics & Gynecology and Reproductive Biology, 258:317-323. Schury MP, Adigun R. Sheehan Syndrome. StatPearls Publishing; 2022 Jan.

Psychiatry.dev -  All Abstracts TTS
Antipsychotic dose reduction compared to dose continuation for people with schizophrenia – PubMed

Psychiatry.dev - All Abstracts TTS

Play Episode Listen Later Nov 25, 2022


https://psychiatry.dev/wp-content/uploads/speaker/post-10956.mp3?cb=1669381231.mp3 Playback speed: 0.8x 1x 1.3x 1.6x 2x Download: Antipsychotic dose reduction compared to dose continuation for people with schizophrenia – PubMed Review Alessandro Rodolico et al. Cochrane Database of SystematicFull EntryAntipsychotic dose reduction compared to dose continuation for people with schizophrenia – PubMed

Psychiatry.dev -  All Abstracts TTS
Exercise for acutely hospitalised older medical patients – PubMed

Psychiatry.dev - All Abstracts TTS

Play Episode Listen Later Nov 14, 2022


https://psychiatry.dev/wp-content/uploads/speaker/post-10798.mp3?cb=1668430052.mp3 Playback speed: 0.8x 1x 1.3x 1.6x 2x Download: Exercise for acutely hospitalised older medical patients – PubMed Review Peter Hartley et al. Cochrane Database of Systematic Reviews. 2022. Approximately 30%Full EntryExercise for acutely hospitalised older medical patients – PubMed

Evidence Based Birth®
EBB 244 - Evidence on Artificial Rupture of Membranes, Assisted Vaginal Delivery, and Internal Monitoring

Evidence Based Birth®

Play Episode Listen Later Nov 2, 2022 35:01


EBB 244: Evidence on Artificial Rupture of Membranes, Assisted Vaginal Delivery, and Internal Monitoring.   We are so excited to announce the upcoming release of a new Evidence Based Birth(R) Pocket Guide, all about Interventions! To give you a sneak peek to the Invention Pocket Guide,  we are diving into the research and evidence on artificial rupture of membranes, assisted vaginal delivery an internal monitoring.   Content note: Discussion of the benefits and risks of these interventions, including forceps and vacuum-assisted deliveries, which can be associated with birthing trauma for birthing people and babies, as well as the risk of mortality. Resources: Make sure you're on the Pocket Guide wait list by going here  Amniotomy References: Kawakita, T., Huang, C-C, and Landy, H. J. (2018). Risk Factors for Umbilical Cord Prolapse at the Time of Artificial Rupture of Membranes. AJP Rep 8(2): e89-e94. https://pubmed.ncbi.nlm.nih.gov/29755833/ Simpson, K. R. (2020). Cervical Ripening and Labor Induction and Augmentation, 5th Edition. AWHONN Practice Monograph 24(4): PS1-S41. https://bmcpregnancychildbirth.biomedcentral.com/articles/10.1186/s12884-019-2491-4 Smyth, R. M., Markham, C. & Dowswell, T. (2013). Amniotomy for shortening spontaneous labour. Cochrane Database Syst Rev 6:CD006167. https://pubmed.ncbi.nlm.nih.gov/23780653/ Alfirevic, Z., Keeney, E., Dowswell, T., et al. (2016). Methods to induce labour: a systematic review, network meta-analysis and cost-effectiveness analysis. BJOG 123(9):  1462-1470. https://pubmed.ncbi.nlm.nih.gov/27001034/  de Vaan, M. D. T., ten Eikelder, M. L. G., Jozwiak, M., et al. (2019). Mechanical methods for induction of labour. Cochrane Database of Systematic Reviews 10: CD001233. https://www.cochrane.org/CD001233/PREG_mechanical-methods-induction-labour Simpson, K. R. (2020). Cervical Ripening and Labor Induction and Augmentation, 5th Edition. AWHONN Practice Monograph, 24(4), PS1-S41. https://nwhjournal.org/article/S1751-4851(20)30079-9/abstract   Assisted Vaginal Delivery References: NHS article on forceps or vacuum delivery https://www.nhs.uk/pregnancy/labour-and-birth/what-happens/forceps-or-vacuum-delivery/ Bailey, P. E., van Roosmalen, J., Mola, G., et al. (2017). Assisted vaginal delivery in low and middle income countries: an overview. BJOG 124(9): 1335-1344. https://pubmed.ncbi.nlm.nih.gov/28139878/ CDC Wonder Database Feeley, C., Crossland, N., Betran, A. P., et al. (2021). Training and expertise in undertaking assisted vaginal delivery (AVD): a mixed methods systematic review of practitioners views and experiences. Reprod Health 18(1): 92. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097768/ Crossland, N., Kingdon, C., Balaam, M. C. (2020). Women's, partners' and health care providers' views and experiences of assisted vaginal birth: a systematic mixed methods review. Reprod Health 17:83. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268509/ Hook, C. D., Damos, J. R. (2008). Vacuum-Assisted Vaginal Delivery. Am Fam Physician 78(8): 953-960. https://www.aafp.org/afp/2008/1015/p953.html Tsakiridis, I., Giouleka, S., Mamopoulos, A., et al. (2020). Operative vaginal delivery: a review of four national guidelines. J Perinat Med 48(3): 189-198. https://pubmed.ncbi.nlm.nih.gov/31926101/ Verma, G. L., Spalding, J. J., Wilkinson, M. D., et al. (2021). Instruments for assisted vaginal birth. Cochrane Database Syst Rev. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD005455.pub3/full   Internal Monitoring References: Euliano, T. Y., Darmanjian, S., Nguyen, M. T., et al. (2017). Monitoring fetal heart rate during labor: A comparison of three methods. J Pregnancy 2017: 8529816. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368359/ Neilson, J. P. (2015). Fetal electrocardiogram (ECG) for fetal monitoring during labor. Cochrane Database Syst Rev 12: CD000116. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000116.pub5/full Harper, L. M., Shanks, A. L., Tuuli, M. G., et al. (2013). The risks and benefits of internal monitors in laboring patients. Am J Obstet Gynecol 209(1): 38.e1-38.e6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760973/ Bakker, J. J. H., Verhoeven, C. J. M., Janssen, P. F., et al. (2010). Outcomes after internal versus external tocodynamometry for monitoring labor. N Engl J Med 362(4): 306-13. https://www.nejm.org/doi/10.1056/NEJMoa0902748?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200www.ncbi.nlm.nih.gov Frolova, A. I., Stout, M. J., Carter, E. B., et al. (2021). Internal fetal and uterine monitoring in obese patients and maternal obstetrical outcomes. Am J Obstet Gynecol MFM 3(1): 100282. https://pubmed.ncbi.nlm.nih.gov/33451595/ Bakker, J. J. H., Janssen, P. F., van Halem, K. (2013). Internal versus external tocodynamometry during induced or augmented labor. Cochrane Database Syst Rev 8: CD006947. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD006947.pub3/full van Halem, K., Bakker, J. J. H., VerHoeven, C. J., et al. (2011). Does use of an intrauterine catheter during labor increase risk of infection? J Maternal Fetal Neonatal Med 25(4): 415-418. https://www.tandfonline.com/doi/abs/10.3109/14767058.2011.582905 For more information and news about Evidence Based Birth®, visit www.ebbirth.com. Find us on:  TikTok Instagram  Pinterest   Ready to get involved?  Check out our Professional membership (including scholarship options) here  Find an EBB Instructor here  Click here to learn more about the Evidence Based Birth® Childbirth Class.

The Hand to Shoulder Podcast
025: Mirror Mirror on the Wall (Mirror Box Therapy) with Miranda Materi OTD, OTR/L, CHT

The Hand to Shoulder Podcast

Play Episode Listen Later Oct 25, 2022 41:43


Take a look in the mirror! Have you ever used mirror box therapy to help restore normal movement patterns? Join us where we reunite with Miranda Materi OTD, OTR/L, CHT from Phoenix, AZ discuss how Mirror Box Therapy can help with many different diagnoses from amputations to CRPS and even just stiffness. Miranda dives into how Mirror Box Therapy can be built at home in a “do it yourself” fashion or references where to buy a Mirror Box Kit. Please refer below for newer research articles found to support use of Mirror Box Therapy with your hand patients! CRPS and Mirror Box G. Lorimer Moseley, Alberto Gallace, Charles Spence, Is mirror therapy all it is cracked up to be? Current evidence and future directions, PAIN,Volume 138, Issue 1,2008,Pages 7-10, ISSN 0304-3959 https://doi.org/10.1016/j.pain.2008.06.026. (https://www.sciencedirect.com/science/article/pii/S0304395908003710) Amputees and Mirror Box Timms, Jason, and Catherine Carus. "Mirror therapy for the alleviation of phantom limb pain following amputation: A literature review." International Journal of Therapy and Rehabilitation 22.3 (2015): 135-145. Stroke and Mirror Box Thieme H, Morkisch N, Mehrholz J, Pohl M, Behrens J, Borgetto B, Dohle C. Mirror therapy for improving motor function after stroke. Cochrane Database of Systematic Reviews 2018, Issue 7. Art. No.: CD008449. DOI: 10.1002/14651858.CD008449.pub3. Accessed 05 October 2022. Hand Trauma and Mirror Box Grünert-Plüss, Nicole, et al. "Mirror therapy in hand rehabilitation: a review of the literature, the St Gallen protocol for mirror therapy and evaluation of a case series of 52 patients." The British Journal of Hand Therapy 13.1 (2008): 4-11.

Addiction Medicine Journal Club
9. Psilocybin for Alcohol Use Disorder

Addiction Medicine Journal Club

Play Episode Listen Later Oct 24, 2022 39:22


In episode 9 we discuss psilocybin for treating alcohol use disorder.Bogenschutz MP, Ross S, Bhatt S, et al. Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2022;79(10):953–962. doi:10.1001/jamapsychiatry.2022.2096----------We talk about Wal-Mart and CVS not filling some telemedicine prescriptions. We also discuss gabapentin involvement in overdose deaths and the efficacy of gabapentin for neuropathic pain.Mattson CL, Chowdhury F, Gilson TP. Notes from the Field: Trends in Gabapentin Detection and Involvement in Drug Overdose Deaths — 23 States and the District of Columbia, 2019–2020. MMWR Morb Mortal Wkly Rep 2022;71:664–666Wiffen PJ, Derry S, Bell RF, Rice ASC, Tölle TR, Phillips T, Moore RA. Gabapentin for chronic neuropathic pain in adults. Cochrane Database of Systematic Reviews 2017, Issue 6. Art. No.: CD007938. DOI: 10.1002/14651858.CD007938.pub4. Accessed 21 October 2022----------This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice. The best part of any journal club is the conversation, and we want to hear what you have to say. To have your opinions about the articles included in a future episode, send us your comments on Twitter or email, or join our Facebook group to continue the discussion.Email: addictionmedicinejournalclub@gmail.com Twitter: @AddictionMedJC Facebook: @AddictionMedJCCredits:Original theme music: composed and performed by Benjamin KennedyAudio production: Angela OhlfestAddiction Medicine Journal Club is intended for educational purposes only, and should not be considered medical advice. The views expressed here are our own, and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities.

The Benzo Free Podcast
The FACTS: What Do We Really Know About Benzos and BIND?

The Benzo Free Podcast

Play Episode Listen Later Oct 1, 2022 65:19


Share this post with others: Are benzos effective for treating anxiety? Insomnia? Seizures? If they aren't safe, what is the evidence? How many BIND symptoms are there? Could these be permanent? And what about COVID? Tune in for the surprising answers. In today's episode, we ask some key questions about benzos and provide real answers, with evidence to back them. We also share questions from our international listeners on CBD and probiotics, and we hear a powerful story of one woman's struggle with her third attempt at withdrawal. This one if chock full of information, and I hope you'll join us. Welcome to Episode #107 Today, we use our standard format to answer a couple of questions from our listeners, share an emotional benzo story, and answer several questions about benzos, withdrawal, and BIND. This episode is full of useful information and references and I hope you enjoy it. Video ID: BFP107 Chapters 0:00:00  INTRODUCTION0:01:16  About the Last Episode0:02:17  Behind the Scenes Work0:03:18  Hurricane Ian0:05:38  MAILBAG0:05:54  Benzo Belly and Probiotics (Jon)0:11:48  CBD and Withdrawal (Julie)0:17:29  BENZO STORY (Jessica)0:26:48  Response from D0:31:20  FEATURE: Benzo Facts0:32:48  Are Benzos Effective?0:35:23  Are Benzos Safe?0:43:49  Can You Be Addicted to Benzos?0:44:46  Is BIND an Official Term?0:47:21  How Many BIND Symptoms Are There?0:52:05  Is BIND Permanent?0:56:42  Are Z-drugs the Same as Benzos?0:57:22  Do Benzos Have an Effect on COVID?1:00:58  MOMENT OF PEACE Episode Resources The following resource links are provided as a courtesy to our listeners. They do not constitute an endorsement by Benzo Free of the resource or any recommendations or advice provided therein. — Benzodiazepine Action Work Group (BAWG) — https://benzoaction.org— Benzodiazepine Information Coalition (BIC) — https://benzoinfo.com— The Alliance for Benzodiazepine Best Practices — https://benzoreform.org— Blazing Benzos Facebook Group — https://m.facebook.com/groups/1205287192817668/ References MAILBAG Grinspoon, Peter. Cannabidiol (CBD): What we know and what we don't. Harvard Health Publishing. September 24, 2021. Accessed September 27, 2022. https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476. FEATURE Ashton, C. Heather. Benzodiazepines: How They Work and How to Withdraw (aka The Ashton Manual). 2002. Accessed April 13, 2016. http://www.benzo.org.uk/manual.Ashton, C. Heather. Benzodiazepines: The Still Unfinished Story. (Speech at Beat the Benzos Launch Conference, Croyden, London, England). https://www.benzo.org.uk/ashspeech.htm.Bachhuber, Marcus A., Sean Hennessy, Chinazo O. Cunningham and Joanna L. Starrels. "Increasing Benzodiazepine Prescriptions and Overdose Mortality in the United States, 1996-2013." American Journal of Public Health (AJPH) (April 2016). Accessed April 7, 2018. doi:10.2105/AJPH.2016.303061.Benzodiazepine Information Coalition (BIC). Withdrawal & Post Withdrawal Symptoms. Accessed September 29, 2022. https://www.benzoinfo.com/benzodiazepine-withdrawal-post-withdrawal-symptoms/.Breilmann J, Girlanda F, Guaiana G, Barbui C, Cipriani A, Castellazzi M, Bighelli I, Davies SJC, Furukawa TA, Koesters M. Benzodiazepines versus placebo for panic disorder in adults. Cochrane Database of Systematic Reviews 2019, Issue 3. Art. No.: CD010677. DOI: 10.1002/14651858.CD010677.pub2. Accessed 27 September 2022. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010677.pub2/full.Commonwealth of Pennsylvania. Prescribing Guidelines for Pennsylvania: Safe Prescribing Benzodiazepines for Acute Treatment of Anxiety & Insomnia. Updated May 15, 2017. Accessed April 7, 2018. http://www.health.pa.gov/My%20Health/Diseases%20and%20Conditions/M-P/opioids/Documents/PA%20Guidelines%20on%20Benzo%20Prescribing.pdf.Easing Anxiety. BIND Symptoms. https://easinganxiety.com/blog/bind-symptoms/.Foster, D E.

Psychiatry.dev -  All Abstracts TTS
Overall prognosis of preschool autism spectrum disorder diagnoses – PubMed

Psychiatry.dev - All Abstracts TTS

Play Episode Listen Later Sep 29, 2022


https://psychiatry.dev/wp-content/uploads/speaker/post-10100.mp3?cb=1664472167.mp3 Playback speed: 0.8x 1x 1.3x 1.6x 2x Download: Overall prognosis of preschool autism spectrum disorder diagnoses – PubMed Review Amanda Brignell et al. Cochrane Database of Systematic Reviews. 2022. AutismFull EntryOverall prognosis of preschool autism spectrum disorder diagnoses – PubMed

Psychiatry.dev -  All Abstracts TTS
Crisis interventions for adults with borderline personality disorder – PubMed

Psychiatry.dev - All Abstracts TTS

Play Episode Listen Later Sep 28, 2022


https://psychiatry.dev/wp-content/uploads/speaker/post-10057.mp3?cb=1664388885.mp3 Playback speed: 0.8x 1x 1.3x 1.6x 2x Download: Crisis interventions for adults with borderline personality disorder – PubMed Review Jonathan Monk-Cunliffe et al. Cochrane Database of Systematic Reviews. 2022. PeopleFull EntryCrisis interventions for adults with borderline personality disorder – PubMed

Birthing in Finland
#24: Acupuncture for gestational migraine and obstetrics, and the integrative exploration of the treatment of primary and secondary infertility with Sari Tjurin-Zeiger

Birthing in Finland

Play Episode Listen Later Sep 26, 2022 55:33


On today's episode I'll be chatting with Sari Tjurin-Zeiger. Sari is an acupuncturist specializing in gynecology, obstetrics, and reproductive medicine. In this episode you will find out what kinds of challenges Sari can help people with, why scientific research is so important to inform the working practice, and how it supports reproductive health including secondary subfertility. We spoke about how secondary infertility sometimes receives less attention and those who are experiencing it may feel marginalized. Sari is a great person to know for your entire parenting journey from conception to postpartum and beyond and that's why she's a guest on the podcast. Let's get started with this deep dive into acupuncture. Show notes: Schedule an appointment with Sari: https://www.eiransairaala.fi/fi/Asiantuntijat/Tjurin-Zeiger-Sari Scientific literature and references: 1. Allais G, Chiarle G, Sinigaglia S, et al. Acupuncture treatment of migraine, nausea, and vomiting in pregnancy. Neurol Sci. 2019;40(Suppl 1):213-215. doi:10.1007/s10072-019- 03799-2 2. Dehghani AS, Homayouni K, Kanannejad Z, Kanannejad Z. The effect of acupuncture on the day of embryo transfer on the in vitro fertilization outcomes: An RCT. Int J Reprod Biomed. 2020;18(3):209-214. doi:10.18502/ijrm.v18i3.6719 3. Bäumler P, Zhang W, Stübinger T, Irnich D. Acupuncture-related adverse events: systematic review and meta-analyses of prospective clinical studies. BMJ Open. 2021;11(9):e045961. doi:10.1136/bmjopen-2020-045961 4. Linde K, Allais G, Brinkhaus B, et al. Acupuncture for the prevention of episodic migraine. Cochrane Database of Systematic Reviews. 2016;(6). doi:10.1002/14651858.CD001218.pub3 5. Lokugamage AU, Eftime VAI, Porter D, Ahillan T, Ke SX. Birth preparation acupuncture for normalising birth: An analysis of NHS service routine data and proof of concept. Journal of Obstetrics and Gynaecology. 2020;40(8):1096-1101. doi:10.1080/01443615.2019.1694878 6. Park J, Sohn Y, White AR, Lee H. The safety of acupuncture during pregnancy: a systematic review. Acupunct Med. 2014;32(3):257-266. doi:10.1136/acupmed-2013- 010480 9. Paulus WE, Zhang M, Strehler E, El-Danasouri I, Sterzik K. Influence of acupuncture on the pregnancy rate in patients who undergo assisted reproduction therapy. Fertility and Sterility. 2002;77(4):721-724. doi:10.1016/S0015-0282(01)03273-3 10. Hullender Rubin LE, Opsahl MS, Wiemer K, Mist SD, Caughey AB. Impact of Whole Systems Traditional Chinese Medicine on In Vitro Fertilization Outcomes. Reprod Biomed Online. 2015;30(6):602-612. doi:10.1016/j.rbmo.2015.02.005 11. Khorram N, Horton S, Sahakian V, Chacon R, Khorram O. Adjuvant acupuncture reduces first trimester pregnancy loss after IVF. Open Journal of Obstetrics and Gynecology. 2012;02. doi:10.4236/ojog.2012.23059 Interesting to read: 12 FinnAcu. Akupunktion tietopaketti. Published 2021. Accessed September 26, 2022. https://finnacu.fi/akupunktion-tietopaketti/ 13. Rubin LH, DAOM, LAc, Medicine FA at OR, Studio PA. How Acupuncture Impacts IVF Success Rates. FertilityIQ. https://www.fertilityiq.com/topics/acupuncture-for- fertility/how-acupuncture-impacts-ivf-success-rates 14. Tjurin-Zeiger S. Akupunktio hedelmöityshoitojen ja raskauden tukena - Dextra Lapsettomuusklinikka. Published March 23, 2021. https://www.dextralapsettomuusklinikka.fi/blogi/2021/03/23/akupunktio- hedelm%C3%B6ityshoitojen-ja-raskauden-tukena/

Psychiatry.dev -  All Abstracts TTS
Pharmacological interventions for the treatment of disordered and problem gambling – PubMed

Psychiatry.dev - All Abstracts TTS

Play Episode Listen Later Sep 23, 2022


https://psychiatry.dev/wp-content/uploads/speaker/post-9938.mp3?cb=1663954206.mp3 Playback speed: 0.8x 1x 1.3x 1.6x 2x Download: Pharmacological interventions for the treatment of disordered and problem gambling – PubMed Review Nicki Dowling et al. Cochrane Database of Systematic Reviews.Full EntryPharmacological interventions for the treatment of disordered and problem gambling – PubMed

Psychiatry.dev -  All Abstracts TTS
Opioid agonist treatment for people who are dependent on pharmaceutical opioids – PubMed

Psychiatry.dev - All Abstracts TTS

Play Episode Listen Later Sep 8, 2022


https://psychiatry.dev/wp-content/uploads/speaker/post-9516.mp3?cb=1662663510.mp3 Playback speed: 0.8x 1x 1.3x 1.6x 2x Download: Opioid agonist treatment for people who are dependent on pharmaceutical opioids – PubMed Review Suzanne Nielsen et al. Cochrane Database of SystematicFull EntryOpioid agonist treatment for people who are dependent on pharmaceutical opioids – PubMed

Exercício Físico e Ciência
Fisio e Ciência #4 – Ultrassom terapêutico para dor

Exercício Físico e Ciência

Play Episode Listen Later Aug 24, 2022 8:01


Nesse episódio vamos discutir as evidências do uso do ultrassom terapêutico na dor, segue as referências citadas: Ebadi, Safoora, et al. "Therapeutic ultrasound for chronic low back pain." Cochrane Database of Systematic Reviews 7 (2020). Qing, Wanyi, et al. "Effect of therapeutic ultrasound for neck pain: a systematic review and meta-analysis." Archives of Physical Medicine and Rehabilitation 102.11 (2021): 2219-2230. Aiyer, Rohit, et al. "Therapeutic ultrasound for chronic pain management in joints: a systematic review." Pain Medicine 21.7 (2020): 1437-1448. Gostou desse episódio? Ficou com alguma dúvida? Quer contribuir com o tema? Me segue e me conta no Instagram @thaissiqueira.fisio --- Support this podcast: https://anchor.fm/fabio-dominski/support

Podcast POEMS BVS APS
Rastreamento do câncer de pulmão através da Tomografia Computadorizada de Baixa Dose.

Podcast POEMS BVS APS

Play Episode Listen Later Aug 15, 2022 7:08


Este é o último episódio do Podcast POEMs da temporada 1 e nele vamos falar sobre uma publicação de agosto de 2022 na biblioteca Cochrane falando sobre o rastreamento do câncer de pulmão através do uso da Tomografia Computadorizada de Baixa Dosagem. Também aproveito para realizar uma revisão breve da temporada e do prazer que foi apresentar os podcasts. Artigo original: Bonney A, Malouf R, Marchal C, Manners D, Fong KM, Marshall HM, Irving LB, Manser R. Impact of low‐dose computed tomography (LDCT) screening on lung cancer‐related mortality. Cochrane Database of Systematic Reviews 2022, Issue 8. Art. No.: CD013829. DOI: 10.1002/14651858.CD013829.pub2. Acessado em 12 de agosto de 22. Disponível em: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD013829.pub2/full/pt

Cows on the Planet
More than milk and meat from cows?

Cows on the Planet

Play Episode Listen Later Jul 8, 2022 26:01


Join Tim and Kim as they talk  with Dr. Hsin Huang, Secretary General of the International Meat Secretariat about some of the surprising products that come from cows other than milk and meat.  CitationsAlam, A. Y. (n.d.). The challenge of dealing with animal derived ingredients in medical/surgical products. 3.Alao, B., Falowo, A., Chulayo, A., & Muchenje, V. (2017). The Potential of Animal By-Products in Food Systems: Production, Prospects and Challenges. Sustainability, 9(7), 1089. https://doi.org/10.3390/su9071089Jayathilakan, K., Sultana, K., Radhakrishna, K., & Bawa, A. S. (2012). Utilization of byproducts and waste materials from meat, poultry and fish processing industries: A review. Journal of Food Science and Technology, 49(3), 278–293. https://doi.org/10.1007/s13197-011-0290-7Khouw, B. T., Rubin, L. J., & Berry, B. (n.d.). Meat Animal By-Products of Pharmaceutical and Food Interest. 8.Quin, J. (2020). Medicines/pharmaceuticals of animal origin. 33.Singh, N., Halliday, H. L., Stevens, T. P., Suresh, G., Soll, R., & Rojas-Reyes, M. X. (2015). Comparison of animal-derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm infants. Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.CD010249.pub2Toldrá, F., Reig, M., & Mora, L. (2021). Management of meat by- and co-products for an improved meat processing sustainability. Meat Science, 181, 108608. https://doi.org/10.1016/j.meatsci.2021.108608

Speak Up
Childhood Apraxia of Speech: Research to Know and Games to Play - S04 E23

Speak Up

Play Episode Listen Later Jul 6, 2022 57:00


In this week's slightly longer episode, SPA's Anneke Flinn speaks with Dr Kieran Flanagan, Senior Lecturer and Course Coordinator of Speech Pathology at Australian Catholic University in Queensland. Kieran explores three current research papers in the area of Childhood Apraxia of Speech: Murray, E., Iuzzini-Seigel, J., Maas, E., Terband, H., & Ballard, K. J. (2021). Differential diagnosis of childhood apraxia of speech compared to other speech sound disorders: A systematic review [Review]. American Journal of Speech-Language Pathology, 30(1), 279-300. Morgan, A. T., Murray, E., & Liégeois, F. J. (2018). Interventions for childhood apraxia of speech [Review]. Cochrane Database of Systematic Reviews, 2018(5), Article Cd006278. This paper can be accessed by following this link: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD006278.pub3/full Strand, E. A. (2020). Dynamic temporal and tactile cueing: A treatment strategy for childhood apraxia of speech. American Journal of Speech-Language Pathology, 29(1), 30-48. Please email Anneke at speakuppodcast@speechpathologyaustralia.org.au if you would like a list of references mentioned in this episode. Speech Pathology Australia acknowledges the Traditional Custodians of lands, seas and waters throughout Australia, and pay respect to Elders past, present and future. We recognise that the health and social and emotional wellbeing of Aboriginal and Torres Strait Islander peoples are grounded in continued connection to culture, country, language and community, and acknowledge that sovereignty was never ceded.

Neonatal Resources, the Podcast

Perhaps the cutest of the ages, the “almost grown enough to skip the NICU” moderate preterm babies are the topic this week. These babies are 32 and 0/7-weeks to 33 and 6/7-weeks but the discussion extends to the late pretermers who find themselves in a NICU. There has been so much research in the last few years about these babies and the things that impact them both short and long term! Join us as we discuss:Cue based feeding in the moderate/late pretermBetamethasone and Magnesium sulfate in this group and how it impacts infants at deliveryWhat it means to support an infant's natural ability vs impose medical standards Early neonatal research (the name wouldn't come during our recording but, if you want to know, it was Dr. Edgar Rey Sanabria in 1978)As if all of that wasn't fun enough…we also talk about jaundice, the plague…and zombies?!?! Honestly, we haven't laughed that hard in a long time! We hope you will laugh along with us. If our suspicions are correct, this won't be the last time this comes up!Bibliography:Bulut,  A., Cundubey, C., Ceyhan, V., & Aydin, E. (2022). Comparison of neonatal  outcomes with and without the administration of betamethasone in late preterm  births. International Journal of Gynecology and Obstetrics, 349-354.  doi:10.1002/ijgo.14028Chollat, C.,  Sentilhes, L., & Marret, S. (2018). Fetal neuroprotection by magnesium  sulfate: from translational research to clinical application. Frontiers in  Neurology, 247.Conde-Agudelo,  A., & Diaz-Rossello, J. (2016). Kangaroo mother care to reduce morbidity  and mortality in low birth weight infants. Cochrane Database of Systematic  Reviews(8), Art. No.: CD002771. doi:10.1002/14651858.CD002771.pub4Kamran, F.,  Khatoonabadi, A. R., Aghajanzadeh, M., Ebadi, A., Faryadras, Y., & Sagheb,  S. (2020). Effectiveness of cue-based feeding versus scheduled feeding in  preterm infants using comprehensive feeding assessment scales: a randomized  clinical trial. Iran Journal of Pediatrics, :e107475.  doi:10.5812/ijp.107475.Woythaler MS, DO,  M. (2019). Neurodevelopmental outcomes of the late preterm infant. Seminars  in Fetal and Neonatal Medicine, 54-59. doi:10.1016/j.siny.2018.10.002Notes:EDC – Estimated date of confinement, also call the estimated  date of delivery (EDD) or the due date. This uses the date of the last  menstrual period to estimate the date of a 40-week, full term delivery. The calculation  is based on Naegele's rule. If you want a  cheat try this calculator.  Gestational Age – The number of completed weeks of a  pregnancy at the time of delivery. Clinically, the gestational age assessment  is based on the EDC, fetal ultrasound measurements, and gestational age  scoring done at delivery. Check out this Get Your Pens for an in-depth look

Neonatal Resources, the Podcast

Perhaps the cutest of the ages, the “almost grown enough to skip the NICU” moderate preterm babies are the topic this week. These babies are 32 and 0/7-weeks to 33 and 6/7-weeks but the discussion extends to the late pretermers who find themselves in a NICU. There has been so much research in the last few years about these babies and the things that impact them both short and long term! Join us as we discuss:Cue based feeding in the moderate/late pretermBetamethasone and Magnesium sulfate in this group and how it impacts infants at deliveryWhat it means to support an infant's natural ability vs impose medical standards Early neonatal research (the name wouldn't come during our recording but, if you want to know, it was Dr. Edgar Rey Sanabria in 1978)As if all of that wasn't fun enough…we also talk about jaundice, the plague…and zombies?!?! Honestly, we haven't laughed that hard in a long time! We hope you will laugh along with us. If our suspicions are correct, this won't be the last time this comes up!Bibliography:Bulut,  A., Cundubey, C., Ceyhan, V., & Aydin, E. (2022). Comparison of neonatal  outcomes with and without the administration of betamethasone in late preterm  births. International Journal of Gynecology and Obstetrics, 349-354.  doi:10.1002/ijgo.14028Chollat, C.,  Sentilhes, L., & Marret, S. (2018). Fetal neuroprotection by magnesium  sulfate: from translational research to clinical application. Frontiers in  Neurology, 247.Conde-Agudelo,  A., & Diaz-Rossello, J. (2016). Kangaroo mother care to reduce morbidity  and mortality in low birth weight infants. Cochrane Database of Systematic  Reviews(8), Art. No.: CD002771. doi:10.1002/14651858.CD002771.pub4Kamran, F.,  Khatoonabadi, A. R., Aghajanzadeh, M., Ebadi, A., Faryadras, Y., & Sagheb,  S. (2020). Effectiveness of cue-based feeding versus scheduled feeding in  preterm infants using comprehensive feeding assessment scales: a randomized  clinical trial. Iran Journal of Pediatrics, :e107475.  doi:10.5812/ijp.107475.Woythaler MS, DO,  M. (2019). Neurodevelopmental outcomes of the late preterm infant. Seminars  in Fetal and Neonatal Medicine, 54-59. doi:10.1016/j.siny.2018.10.002Notes:EDC – Estimated date of confinement, also call the estimated  date of delivery (EDD) or the due date. This uses the date of the last  menstrual period to estimate the date of a 40-week, full term delivery. The calculation  is based on Naegele's rule. If you want a  cheat try this calculator.  Gestational Age – The number of completed weeks of a  pregnancy at the time of delivery. Clinically, the gestational age assessment  is based on the EDC, fetal ultrasound measurements, and gestational age  scoring done at delivery. Check out this Get Your Pens for an in-depth look

Neonatal Resources, the Podcast

Perhaps the cutest of the ages, the “almost grown enough to skip the NICU” moderate preterm babies are the topic this week. These babies are 32 and 0/7-weeks to 33 and 6/7-weeks but the discussion extends to the late pretermers who find themselves in a NICU. There has been so much research in the last few years about these babies and the things that impact them both short and long term! Join us as we discuss:Cue based feeding in the moderate/late pretermBetamethasone and Magnesium sulfate in this group and how it impacts infants at deliveryWhat it means to support an infant's natural ability vs impose medical standards Early neonatal research (the name wouldn't come during our recording but, if you want to know, it was Dr. Edgar Rey Sanabria in 1978)As if all of that wasn't fun enough…we also talk about jaundice, the plague…and zombies?!?! Honestly, we haven't laughed that hard in a long time! We hope you will laugh along with us. If our suspicions are correct, this won't be the last time this comes up!Bibliography:Bulut,  A., Cundubey, C., Ceyhan, V., & Aydin, E. (2022). Comparison of neonatal  outcomes with and without the administration of betamethasone in late preterm  births. International Journal of Gynecology and Obstetrics, 349-354.  doi:10.1002/ijgo.14028Chollat, C.,  Sentilhes, L., & Marret, S. (2018). Fetal neuroprotection by magnesium  sulfate: from translational research to clinical application. Frontiers in  Neurology, 247.Conde-Agudelo,  A., & Diaz-Rossello, J. (2016). Kangaroo mother care to reduce morbidity  and mortality in low birth weight infants. Cochrane Database of Systematic  Reviews(8), Art. No.: CD002771. doi:10.1002/14651858.CD002771.pub4Kamran, F.,  Khatoonabadi, A. R., Aghajanzadeh, M., Ebadi, A., Faryadras, Y., & Sagheb,  S. (2020). Effectiveness of cue-based feeding versus scheduled feeding in  preterm infants using comprehensive feeding assessment scales: a randomized  clinical trial. Iran Journal of Pediatrics, :e107475.  doi:10.5812/ijp.107475.Woythaler MS, DO,  M. (2019). Neurodevelopmental outcomes of the late preterm infant. Seminars  in Fetal and Neonatal Medicine, 54-59. doi:10.1016/j.siny.2018.10.002Notes:EDC – Estimated date of confinement, also call the estimated  date of delivery (EDD) or the due date. This uses the date of the last  menstrual period to estimate the date of a 40-week, full term delivery. The calculation  is based on Naegele's rule. If you want a  cheat try this calculator.  Gestational Age – The number of completed weeks of a  pregnancy at the time of delivery. Clinically, the gestational age assessment  is based on the EDC, fetal ultrasound measurements, and gestational age  scoring done at delivery. Check out this Get Your Pens for an in-depth look

Neonatal Resources, the Podcast

Perhaps the cutest of the ages, the “almost grown enough to skip the NICU” moderate preterm babies are the topic this week. These babies are 32 and 0/7-weeks to 33 and 6/7-weeks but the discussion extends to the late pretermers who find themselves in a NICU. There has been so much research in the last few years about these babies and the things that impact them both short and long term! Join us as we discuss:Cue based feeding in the moderate/late pretermBetamethasone and Magnesium sulfate in this group and how it impacts infants at deliveryWhat it means to support an infant's natural ability vs impose medical standards Early neonatal research (the name wouldn't come during our recording but, if you want to know, it was Dr. Edgar Rey Sanabria in 1978)As if all of that wasn't fun enough…we also talk about jaundice, the plague…and zombies?!?! Honestly, we haven't laughed that hard in a long time! We hope you will laugh along with us. If our suspicions are correct, this won't be the last time this comes up!Bibliography:Bulut,  A., Cundubey, C., Ceyhan, V., & Aydin, E. (2022). Comparison of neonatal  outcomes with and without the administration of betamethasone in late preterm  births. International Journal of Gynecology and Obstetrics, 349-354.  doi:10.1002/ijgo.14028Chollat, C.,  Sentilhes, L., & Marret, S. (2018). Fetal neuroprotection by magnesium  sulfate: from translational research to clinical application. Frontiers in  Neurology, 247.Conde-Agudelo,  A., & Diaz-Rossello, J. (2016). Kangaroo mother care to reduce morbidity  and mortality in low birth weight infants. Cochrane Database of Systematic  Reviews(8), Art. No.: CD002771. doi:10.1002/14651858.CD002771.pub4Kamran, F.,  Khatoonabadi, A. R., Aghajanzadeh, M., Ebadi, A., Faryadras, Y., & Sagheb,  S. (2020). Effectiveness of cue-based feeding versus scheduled feeding in  preterm infants using comprehensive feeding assessment scales: a randomized  clinical trial. Iran Journal of Pediatrics, :e107475.  doi:10.5812/ijp.107475.Woythaler MS, DO,  M. (2019). Neurodevelopmental outcomes of the late preterm infant. Seminars  in Fetal and Neonatal Medicine, 54-59. doi:10.1016/j.siny.2018.10.002Notes:EDC – Estimated date of confinement, also call the estimated  date of delivery (EDD) or the due date. This uses the date of the last  menstrual period to estimate the date of a 40-week, full term delivery. The calculation  is based on Naegele's rule. If you want a  cheat try this calculator.  Gestational Age – The number of completed weeks of a  pregnancy at the time of delivery. Clinically, the gestational age assessment  is based on the EDC, fetal ultrasound measurements, and gestational age  scoring done at delivery. Check out this Get Your Pens for an in-depth look

Stats + Stories
The Winner's Curse | Stats + Stories Episode 232

Stats + Stories

Play Episode Listen Later May 19, 2022 25:56


A randomized controlled trial is viewed as the golden standard in medical research, particularly as it relates to treatments or interventions. But there may be pitfalls to trusting that approach too much. That's the focus of this episode of Stats and Stories with guest Erik van Zwet. -Timestamps- What is a RCT? (1:15), What are characteristic of a well designed trial? (2:00), How did you get interested in this research?(3:45), Data you obtained from Cochrane Database? 5:18), Power and how you got results (7:05), How does affect the laymen (9:49), Coverage of RCTs (12:00), Trends of exaggeration (14:17), What goes into exaggeration? (16:54), What needs to be done? (18:56), Across other fields (21:58) Erik van Zwet (@erikvanzwet) is an Associate Professor in the Department of Biomedical Data Sciences of the Leiden University Medical Center where he has been since 2009. He joined the school wanting to do more applied work in the areas of statistics and data analysis and has since published multiple papers in Significance Magazine including the main focus of today's episode, “Addressing exaggeration of effects from single RCTs”.

Your Parenting Mojo - Respectful, research-based parenting ideas to help kids thrive
152: Everything you need to know about sleep training

Your Parenting Mojo - Respectful, research-based parenting ideas to help kids thrive

Play Episode Listen Later Mar 27, 2022 53:15


We've already covered a couple of episodes on sleep, including the https://yourparentingmojo.com/captivate-podcast/sleep/ (cultural issues associated with sleep), then more recently we talked with https://yourparentingmojo.com/captivate-podcast/restedchild (Dr. Chris Winter about his book The Rested Child) where we looked at sleep issues in older children.   But if you have a young child who isn't sleeping well, from the baby stage all the way up to about preschool, this episode is for you!  My guest is Macall Gordon, senior lecturer in the Department of Psychology at Antioch University Seattle, and who has studied young children's sleep for 20 years.  She's particularly interested in the intersection between children's temperament and their sleep, and how parents of the children she calls 'little livewires' can support these children so everyone gets more sleep.   If you have questions about sleep training - particularly when and how to do it - this episode is for you!   And if you're expecting a baby or have one under the age of one (whether this is your first or not!) you might be interested in the Right From The Start course, which is designed to help you get things right for you from the start.  We go in-depth on understanding topics like sleep, feeding, physical, mental, and emotional development, and more - both for baby and for you!   Get all the (research-backed, of course) information you need, plus a supportive community and four group coaching calls during the 8-week course.  Enrollment is open from April 3-13, and we start together on Monday April 18.  Click the picture below to learn more!     References: Macall Gordon's website, https://www.littlelivewires.com/ (Little Livewires) Adachi, Y., Sato, C., Nishino, N., Ohryoji, F., Hayama, J., & Yamagami, T. (2009). A brief parental education for shaping sleep habits in 4-month- old infants. Clinical Medicine & Research, 7(3), 85–92. Blunden, S., & Baills, A. (2013). Treatment of behavioural sleep problems: Asking the parents. Journal of Sleep Disorders: Treatment and Care, 2(2). Blunden, S., Etherton, H., & Hauck, Y. (2016). Resistance to cry intensive sleep intervention in young children: Are we ignoring children's cries or parental concerns? Children, 3(2), 8. Bryanton, J., & Beck, C. T. (2010). Postnatal parental education for optimizing infant general health and parentinfant relationships. Cochrane Database of Systematic Reviews, 1, CD004068. Byars, K. C., & Simon, S. L. (2016). Behavioral treatment of pediatric sleep disturbance: Ethical considerations for pediatric psychology practice. Clinical Practice in Pediatric Psychology, 4(2), 241. Byars, K. C., Yolton, K., Rausch, J., Lanphear, B., & Beebe, D. W. (2012). Prevalence, patterns, and persistence of sleep problems in the first 3 years of life. Pediatrics, 29(2). Chadez, L. H., & Nurius, P. S. (1987). Stopping bedtime crying: Treating the child and the parents. Journal of Clinical Child Psychology, 16(3), 212–217. Coe, C. L., Glass, J. C., Wiener, S. G., & Levine, S. (1983).Behavioral, but not physiological, adaptation to repeated separation in mother and infant primates. Psychoneuroendocrinology, 8(4), 401-409. Crichton, G. E., & Symon, B. (2016). Behavioral management ofsleep problems in infants under 6 months- -What works? Journal of Developmental and Behavioral Pediatrics, 37(2), 164–171. Cutrona, C. E., & Troutman, B. R. (1986). Social support, infant temperament, and parenting self-efficacy: A mediational model of postpartum depression. Child Development, 1507-1518. Didden, R., De Moor, J., & Kruit, I. W. (1999). The effects of extinction in the treatment of sleep problems with a child with a physical disability. International Journal of Disability, Development and Education, 46(2), 247–252. Douglas, P. S., & Hill, P. S. (2013). Behavioral sleep...

Scottish National Users' Group (SNUG) Podcast

Scotland's House of Care is based on the Year of Care Programme and as this BMJ article explains, is all about delivering person centred care in long term conditions. In this episode of our podcast, we discuss how we can offer Care and Support Planning to patients with long term conditions, as we speak to Dr Graham Kramer @KramerGraham and Lindsay Oliver @lindsayeoliver, two of the leading figures in promoting this approach both in England and Scotland over the past few years. We also hear from Alison Fox, the Practice Manager of St Triduana' s practice in Edinburgh, who have found that Care and support planning really works well for them, and how this has continued to be useful throughout the pandemic. Angela Coulter video: evidence for care and support planning. Cochrane Database review of evidence supporting Care and Support Planning. Many conditions, one life RCGP Person centred Toolkit Alliance video: Patient Reps from Greater Glasgow and Clyde Health and Social Care Partnership explain their experiences with the House of Care and having care and support planning conversations with health professionals. You can contact SNUG by emailing alex.defranco@phs.scot

Make Dementia Your B*tch!
Episode 35: Dementia and Medications for Mood, Sleep, and Behaviors

Make Dementia Your B*tch!

Play Episode Listen Later Mar 1, 2022 33:37


I dive deep into four general categories of medications that are often prescribed for people living with dementia: antidepressants, mood stabilizers, benzodiazepines (spoiler alert--not a good option), and antipsychotics. Learn why these medications are prescribed and what problems may happen when your family member takes them. This information is for educational use only. Consult your healthcare professional before making any medication changes. I hope that this information assists you with having conversations about medications with your healthcare provider. Here are the studies I mention: Seitz DP, Adunuri N, Gill SS, Gruneir A, Herrmann N, Rochon P. Antidepressants for agitation and psychosis in dementia. Cochrane Database of Systematic Reviews. 2011(2). McCleery J, Cohen DA, Sharpley AL. Pharmacotherapies for sleep disturbances in dementia. Cochrane Database Syst Rev. 2016;11:CD009178. Baillon SF, Narayana U, Luxenberg JS, Clifton AV. Valproate preparations for agitation in dementia. Cochrane Database Syst Rev. 2018;10:CD003945. PODCAST CHALLENGE! · Rate and review my podcast on your favorite platform · E-mail me a screenshot before Friday, March 11 at 5 pm central time US; if you want to game the system and rate and review on multiple platforms, go for it! Email: rita.jablonski@gmail.com · 3 winners will receive a signed, autographed copy of my book · Winners will be announced during Episode 37 (which will be dropped Sunday, March 13 2022) CHECK OUT MY BOOK! “Make Dementia Your B*tch! An Easy Guide to Understanding and Handling Dementia-driven Behaviors.” Have a dementia question? Want to hear it answered on a future podcast? Email me: rita.jablonski@gmail.com. Are you a visual learning? Check out my YouTube channel, where I demonstrate strategies like bridging and chaining Looking for a community? I have my own Facebook page for dementia caregivers: Make Dementia Your B! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/rita-a-jablonski/message

Hands In Motion
Wound Care in Hand and Upper Extremity Therapy with Nora Barrett, OTR/L, CHT, WCC

Hands In Motion

Play Episode Listen Later Jan 31, 2022 34:53


Nora Barrett, OTR/L, CHT, WCC joins us to talk about wound care in hand and upper extremity therapy and her recent journey to obtain her certification in wound care. She gives us the most up-to-date information on assessing and treating wounds, and also shares some clinical pearls of what to do, what not to do and how we as hand therapists can advocate for our patients and their wounds. Guest Bio: Nora has been a practicing occupational therapist since 1998 and a certified hand therapist since 2006. She spent her early career as an inpatient therapist at rehabilitation centers, acute care hospitals and burn units in Boston, MA and Washington, DC before focusing on outpatient hands in Washington, DC, Baltimore, MD and Bend, OR. Nora moved to Charlottesville, VA in 2021 and joined the Hand Therapy Team at the University of Virginia Physicians Group where she works in the Hand Center and in an outpatient hand therapy practice. She received her Wound Care Certification in 2020 and is an active member of the American Society of Hand Therapists (ASHT) and the American Association for Hand Surgery (AAHS). She lectures routinely in wound care, burn therapy, trauma and peripheral nerve injury for ASHT, AAHS and various universities across the country.   References : Wound Care References Baranoski S, Ayello E. Wound Care Essentials: Practice Principles. 4th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2015. Broussard KC, Powers, et al. Wound dressings: selecting the most appropriate type. American Journal of Clinical Dermatology. 2013; 14(6):449-459. Eming S. Biology of Wound Healing. In: Bolognia JL, Schaffer JV, Cerroni L. Dermatology. 4th ed. Philadelphia, PA: Elsevier; 2018:2413-2424.e1. Lammers RL, Aldy KN. Principles of Wound Management. In: Roberts JR, Custalow CB. Clinical Procedures in Emergency Medicine and Acute Care. 7th ed. Philadelphia, PA: Elsevier; 2019:621-654. Leaper DJ, Schultz G, Carville K, Fletcher J, Swanson T, Drake R. Extending the TIME concept: what have we learned in the past 10 years? International Wound Journal. 2014; 9 (Suppl.2):1-19. McVeigh K, Herman M, Barrett N. Physiology of Wound Healing and Burns. In: Test Prep for the CHT Exam. 4th ed. American Society of Hand Therapists; 2021. Myers BA. Wound Management: Principles and Practices. 4th ed. Upper Saddle River, NJ: Pearson; 2020. Newell KA. Wound Closure. In: Dehn R, Asprey D. Essential Clinical Procedures. 4th ed. Philadelphia, PA: Elsevier; 2021:325-348. Norman G, Dumville JC, Mohapatra DP, Owens GL, Crosbie EJ. Antibiotics and antiseptics for surgical wound healing by secondary intention (Review). Cochrane Database of Systematic Reviews. 2016; 3. DOI: 10.1002/14651858.CD011712.pub.2. Parrish KP, Barrett NE. Wound classification and management. In: Skirven TM, Osterman LA, Fedorczyk JM, Amadio PC, Feldscher SB, Shin EK. Rehabilitation of the Hand and Upper Extremity. 7th ed. Philadelphia, PA: Elsevier; 2021:196-209. Sen CK, Roy S, Gordillo G. Wound Healing. In: Gurtner GC, Neligan PC. Plastic Surgery: Volume 1: Principles. 4th ed. Philadelphia, PA: Elsevier; 2018:165-195.e7.

2 Paed Chiros
007 - Tongue Tie

2 Paed Chiros

Play Episode Listen Later Jan 19, 2022 57:52


Join Christian and Mike as we chat about the causes, impacts and possible treatments regarding Tongue Tie in infants! Felicity Crone's Tongue Tie course (Time Limited special offer) + 10% off if you use the code 2PAEDCHIROS at checkout https://felicity-crone.mykajabi.com/pl/2147530164 Richard Baxters book - Tongue-Tied https://www.amazon.com/Tongue-Tied-String-Impacts-Nursing-Feeding-ebook/dp/B07FC4HZXX/ref=sr_1_1?crid=241MWY6NTG8I0&keywords=richard+baxter+tongue+tie&qid=1642633095&sprefix=richard+baxter+tongu%2Caps%2C229&sr=8-1 ADDITIONAL REFERENCES: Amitai, Y., Shental, H., Atkins-Manelis, L., Koren, G., & Zamir, C. S. (2020). Pre-conceptional folic acid supplementation: A possible cause for the increasing rates of ankyloglossia. Medical Hypotheses, 134. Baxter, R., & Hughes, L. (2018). Speech and Feeding Improvements in Children After Posterior Tongue-Tie Release: A Case Series. International Journal of Clinical Pediatrics, 7(3), 29–35. Baxter, R., Merkel-Walsh, R., Baxter, B. S., Lashley, A., & Rendell, N. R. (2020). Functional Improvements of Speech, Feeding, and Sleep After Lingual Frenectomy Tongue-Tie Release: A Prospective Cohort Study. Clinical Pediatrics, 59(9–10), 885–892. Ghaheri, B. A., Cole, M., Fausel, S. C., Chuop, M., & Mace, J. C. (2017). Breastfeeding improvement following tongue-tie and lip-tie release: A prospective cohort study. The Laryngoscope, 127(5), 1217–1223. Golja, M. V., Šmid, A., Kuželički, N. K., Trontelj, J., Geršak, K., & Mlinarič-Raščan, I. (2020). Folate Insufficiency Due to MTHFR Deficiency Is Bypassed by 5-Methyltetrahydrofolate. Journal of Clinical Medicine, 9(9), 1–18. Griffiths, D. M. (2004). Do tongue ties affect breastfeeding? Journal of Human Lactation, 20(4), 409–414. Ingram, J., Copeland, M., Johnson, D., & Emond, A. (2019). The development and evaluation of a picture tongue assessment tool for tongue-tie in breastfed babies (TABBY). International Breastfeeding Journal, 14(1), 1–5. Ingram, J., Johnson, D., Copeland, M., Churchill, C., Taylor, H., & Emond, A. (2015). The development of a tongue assessment tool to assist with tongue-tie identification. Archives of Disease in Childhood - Fetal and Neonatal Edition, 100(4), F344–F349. Mills, N., Pransky, S. M., Geddes, D. T., & Mirjalili, S. A. (2019). What is a tongue tie? Defining the anatomy of the in-situ lingual frenulum. Clinical Anatomy, 32(6), 749–761. O'Shea, J. E., Foster, J. P., O'Donnell, C. P. F., Breathnach, D., Jacobs, S. E., Todd, D. A., & Davis, P. G. (2017). Frenotomy for tongue-tie in newborn infants. Cochrane Database of Systematic Reviews, 2017(3). Salt, H., Claessen, M., Johnston, T., & Smart, S. (2020). Speech production in young children with tongue-tie. International Journal of Pediatric Otorhinolaryngology, 134, 110035. Schlatter, S. M., Schupp, W., Otten, J. E., Harnisch, S., Kunze, M., Stavropoulou, D., & Hentschel, R. (2019). The role of tongue-tie in breastfeeding problems—A prospective observational study. Acta Paediatrica, 108(12), 2214–2221. Webb, A. N., Hao, W., & Hong, P. (2013). The effect of tongue-tie division on breastfeeding and speech articulation: A systematic review. International Journal of Pediatric Otorhinolaryngology, 77(5), 635–646.

Curiosity Daily
Quitting Smoking, Over-Practicing, Bill Nye on Believing Science

Curiosity Daily

Play Episode Listen Later Jan 7, 2022 13:42


Learn how quitting smoking helps mental health; how to avoid over-practicing; and how to get people to believe science. Quitting smoking is good for your mental health, too by Steffie Drucker Cochrane Review finds stopping smoking is linked to improved mental health. (2021). EurekAlert! https://www.eurekalert.org/pub_releases/2021-03/w-crf030921.php  ‌Taylor, G. M., Lindson, N., Farley, A., Leinberger-Jabari, A., Sawyer, K., te Water Naudé, R., Theodoulou, A., King, N., Burke, C., & Aveyard, P. (2021). Smoking cessation for improving mental health. Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.cd013522.pub2  University of Birmingham. (2021, March 10). Quitting smoking is linked to improved mental health, research finds. University of Birmingham; University of Birmingham. https://www.birmingham.ac.uk/news/latest/2021/03/quit-smoking-mental-health-vaping.aspx  Alltucker, K. (2021, March 12). Cigarette sales increased during pandemic as fewer smokers sought help quitting. USA TODAY; USA TODAY. https://www.usatoday.com/story/news/health/2021/03/12/cigarette-sales-increase-and-fewer-sought-help-to-quit-smoking-amid-covid-19-anxiety-and-isolation/4664323001/  Smoking and mental health. (2015, August 7). Mental Health Foundation. https://www.mentalhealth.org.uk/a-to-z/s/smoking-and-mental-health   It's Possible to Practice Too Much by Mae Rice Training beyond exhaustion can prevent learning. (2019). EurekAlert! https://www.eurekalert.org/pub_releases/2019-03/e-tbe030519.php  ‌Meret Branscheidt, Panagiotis Kassavetis, Anaya, M., Rogers, D., Han Debra Huang, Lindquist, M. A., & Celnik, P. (2019, March 5). Fatigue induces long-lasting detrimental changes in motor-skill learning. ELife; eLife Sciences Publications, Ltd. https://elifesciences.org/articles/40578  How to get people to believe science, with special guest Bill Nye (listener question from Michelle via HiHo): Official website https://billnye.com/ Bill Nye's podcast, Science Rules! https://www.askbillnye.com/  Pick up “Bill Nye's Great Big World of Science” on Amazon https://amzn.to/3u8iKQi  “Everything All at Once: How to Think Like a Science Guy, Solve Any Problem, and Make a Better World” on Amazon https://amzn.to/3whsk5j Follow @BillNye on Twitter https://twitter.com/BillNye  Follow Curiosity Daily on your favorite podcast app to get smarter withCody Gough andAshley Hamer — for free! Still curious? Get exclusive science shows, nature documentaries, and more real-life entertainment on discovery+! Go to https://discoveryplus.com/curiosity to start your 7-day free trial. discovery+ is currently only available for US subscribers. See omnystudio.com/listener for privacy information.

Ta de Clinicagem
TdC em Bolus - Influenza

Ta de Clinicagem

Play Episode Listen Later Dec 22, 2021 16:44


Fred e Raphael trazem nesse bolus especial, muita informação essencial para essa nova onda de Influenza: quando pensar? E a diferença com COVID? Como diagnosticar e como tratar? Tudo isso aqui! Referências: Call, Stephanie A., et al. "Does this patient have influenza?." Jama 293.8 (2005): 987-997. World Health Organization. "Recommended composition of influenza virus vaccines for use in the 2022 southern hemisphere influenza season–Composition" Punpanich, Warunee, and Tawee Chotpitayasunondh. "A review on the clinical spectrum and natural history of human influenza." International Journal of Infectious Diseases 16.10 (2012): e714-e723. Uyeki, Timothy M., et al. "Clinical practice guidelines by the Infectious Diseases Society of America: 2018 update on diagnosis, treatment, chemoprophylaxis, and institutional outbreak management of seasonal influenza." Clinical Infectious Diseases 68.6 (2019): e1-e47. Gaitonde, David Y., Faith C. Moore, and Mackenzie K. Morgan. "Influenza: Diagnosis and treatment." American family physician 100.12 (2019): 751-758. Rodrigo, Chamira, et al. "Corticosteroids as adjunctive therapy in the treatment of influenza." Cochrane database of systematic reviews 3 (2016). Lansbury, Louise, et al. "Corticosteroids as adjunctive therapy in the treatment of influenza." Cochrane Database of Systematic Reviews 2 (2019). Ni, YN., Chen, G., Sun, J. et al. The effect of corticosteroids on mortality of patients with influenza pneumonia: a systematic review and meta-analysis. Crit Care 23, 99 (2019).

Ta de Clinicagem
Episódio 117: 4 Clinicagens sobre Opioides

Ta de Clinicagem

Play Episode Listen Later Dec 1, 2021 69:42


João, Raphael e Marcela Belleza trazem quatro clinicagens importantes sobre um remédio muito comum da nossa prática médica: os opioides. Como prescrever? Quais efeitos adversos são comuns e como tratar? Como é a intoxicação por opioide? Como usar essa classe na dispneia e na tosse? Tudo isso nesse episódio! Minutagem em breve! Escala RIOSORD de risco de intoxicação por opioides https://paindr.com/wp-content/uploads/2015/09/RIOSORD-tool.pdf Referências: 1. Uptodate Dez 2021. Prevention and management of side effects in patients receiving opioids for chronic pain. Russell K Portenoy,Zankhana Mehta, Ebtesam Ahmed, Janet Abrahm, Diane MF Savarese 2. TASSINARI, Davide et al. Adverse effects of transdermal opiates treating moderate-severe cancer pain in comparison to long-acting morphine: a meta-analysis and systematic review of the literature. Journal of palliative medicine, v. 11, n. 3, p. 492-501, 2008 3. Uptodate Nov 2021. Approach to symptom assessment in palliative care. Victor T Chang, Thomas J Smith, Jane Givens 4. Manual de Cuidados Paliativos - Ministério da Saúde. 2020. 5. Uptodate 2021. Assessment and management of dyspnea in palliative care. Deborah Dudgeon, Eduardo Bruera, Jane Givens,Helen Hollingsworth. 6. JOHNSON, Miriam J.; CURROW, David C. Opioids for breathlessness: a narrative review. BMJ supportive & palliative care, v. 10, n. 3, p. 287-295, 2020. 7. Palliative care: Overview of cough, stridor, and hemoptysis in adults. Charles von Gunten, Gary Buckholz, Eduardo Bruera, Jane Givens. 8. MOLASSIOTIS, Alex et al. Interventions for cough in cancer. Cochrane Database of Systematic Reviews, n. 5, 2015. 9-YANCY JR, William S. et al. Efficacy and tolerability of treatments for chronic cough: a systematic review and meta-analysis. Chest, v. 144, n. 6, p. 1827-1838, 2013. 9. YANCY JR, William S. et al. Efficacy and tolerability of treatments for chronic cough: a systematic review and meta-analysis. Chest, v. 144, n. 6, p. 1827-1838, 2013. 10. Caraceni A, et al. Use of opioid analgesics in the treatment of cancer pain: evidence-based recommendations from the EAPC. European Palliative Care Research Collaborative (EPCRC), on behalf of the European Association for Palliative Care (EAPC) - Lancet Oncol 2012; 13: e58–68 www.thelancet.com/oncology Vol 13 February 2012 11. Jost L, Rolia F. Management of cancer pain: ESMO Clinical Recommendations. Annals of Oncology Volume 19, Supplement 2, May 2008, Pages ii119-ii121 12. Zeppetella, Giovambattista Impact and management of breakthrough pain in cancer, Current Opinion in Supportive and Palliative Care: March 2009 - Volume 3 - Issue 1 - p 1-6 doi: 10.1097/SPC.0b013e3283260658 13. Dowell D, Haegerich TM, Chou R. CDC Guideline for Prescribing Opioids for Chronic Pain — United States, 2016. MMWR Recomm Rep 2016;65(No. RR-1):1–49. DOI: http://dx.doi.org/10.15585/mmwr.rr6501e1 14. Management of Chronic Pain in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline Judith A. Paice, Russell Portenoy, Christina Lacchetti, Toby Campbell, Andrea Cheville, Marc Citron, Louis S. Constine, Andrea Cooper, Paul Glare, Frank Keefe, Lakshmi Koyyalagunta, Michael Levy, Christine Miaskowski, Shirley Otis-Green, Paul Sloan, and Eduardo Bruera Journal of Clinical Oncology 2016 34:27, 3325-3345 15. BABU, Kavita M.; BRENT, Jeffrey; JUURLINK, David N. Prevention of opioid overdose. New England Journal of Medicine, v. 380, n. 23, p. 2246-2255, 2019. 16. Osler, W. "Oedema of left lung-morphia poisoning." Montreal Gen Hosp Rep 1 (1880): 291

Reumatominas
Episodio 35: Canabinoides para dor: prescrição e incertezas

Reumatominas

Play Episode Listen Later Nov 28, 2021 17:55


Neste episódio, contamos com a participação do Dr. Marco Pontes reumatologista pela faculdade de medicina da Universidade de São Paulo, com titulo de reumatologia pela Sociedade Brasileira de Reumatologia e Certificação de área de atuação em Dor pela Associação Medica Brasileira. Referências. 1. Walitt B et al. Cannabinoids for fibromyalgia. Cochrane Database of Systematic Reviews. 2016;7. 2.Campbell G et al. Effect of cannabis use in people with chronic non-cancer pain prescribed opioids. Lancet Public Health. 2018;3: e341–50. 3.Hazlewood GS et al. Cannabis for rheumatic pain: hope or hype? Clin Rheumatol. 2019: Jul 5

Reumatominas
Episodio 34: Canabinoides para dor: história e evidências

Reumatominas

Play Episode Listen Later Nov 21, 2021 18:16


Neste episódio, contamos com a participação do Dr. Marco Pontes reumatologista pela faculdade de medicina da Universidade de São Paulo, com titulo de reumatologia pela Sociedade Brasileira de Reumatologia e Certificação de área de atuação em Dor pela Associação Medica Brasileira. Referências.  1. Walitt B et al. Cannabinoids for fibromyalgia. Cochrane Database of Systematic Reviews. 2016;7. 2.Campbell G et al. Effect of cannabis use in people with chronic non-cancer pain prescribed opioids. Lancet Public Health. 2018;3: e341–50. 3.Hazlewood GS et al. Cannabis for rheumatic pain: hope or hype? Clin Rheumatol. 2019: Jul 5

Medical Myths, Legends & Fairytales
Dangers of Too Much Vitamin D with Dr Deva Boone

Medical Myths, Legends & Fairytales

Play Episode Listen Later Nov 1, 2021 35:08


Between the latest online fads and the crazy media headlines, it's easier more than ever to get confused about your health. If you want to make better decisions about your health so you can feel better and live longer, you've come to the right place.   There are so many questions about Vitamin D today especially in the media regarding its relevance to general health, thyroid health and how it is related to COVID. There are a lot of arguments as to how Vitamin D can be beneficial to humans, and the recent one is its contribution to fight COVID-19. I stumbled across one of Dr. Deva Boone's articles about people easily getting hypercalcemia or high calcium levels even from mild excesses of Vitamin D. I recommended before to avoid higher levels of Vitamin D as it is less useful and makes you less productive but it turns out it can also be quite dangerous.    Joining us is Dr. Deva Boone to understand more of how Vitamin D works in our body and what are the best practices to think about for our general welfare.   Dr. Deva Boone is one of the most experienced parathyroid surgeons and has become a renowned expert on calcium and Vitamin D. She attended Cornell University medical school, completed a general surgery residency in New York City, and an endocrine surgery fellowship in Chicago. She spent the past six years as a parathyroid surgeon at the Norman Parathyroid Center, and was the Medical Director there for the past three years. She is currently obtaining an executive MBA at the University of South Florida, and is planning to open a parathyroid surgery center in Arizona in 2021. Key Takeaways:   [0:35] Introduction to Dr. Deva Boone [2:02] Dr. Boone shares a story about Shannon with a medical mystery. [2:35] Shannon showing symptoms related to Catatonia - a psychiatric disorder. [3:27] Suspected parathyroid disease because of consistent high calcium levels. [4:10] Sharing symptoms with parathyroid disease and psychiatric disorder. [4:45] Dr. Boone examined deeper and shifted to high levels of vitamin D. [5:00] Results of taking vitamin D as a medication for a long period.  [5:40] High levels of vitamin D cause high calcium levels. [6:00] Putting a stop on taking vitamin D as a cure. [6:45] Diagnosing patients with high calcium levels because of vitamin D [7:25] Effects of having high calcium levels. [7:50] Dr. Boone explains vitamin D is a steroid hormone. [9:20] High calcium blood levels that cause toxic range of vitamin D. [11:30] Problems in measuring vitamin D. [13:01] Vitamin D in milk to avoid bone deformities. [13:30] Other health effects of low or high in vitamin D [14:28] Range of vitamin D levels and the health effects according to race. [15:43] Correlation is not causation - associating low vitamin D to a lot of diseases. [17:38] Ignoring high calcium levels and its impact. [18:35] The body keeps a tight range of calcium levels. [19:00] General effects of high calcium levels. [19:50] Hich calcium level is a parathyroid tumor until proven otherwise. [21:01] Normal range of calcium levels according to age. [22:13] Parathyroid surgery as the best cure of parathyroid disease. [24:25]  Considering surgery rather than just maintaining lifestyle medicine. [25:50] How Parathyroid surgery works? [26:55] Vitamin D is not definitive but plays a role in our immune system and could help prevent COVID. [29:40] Taking vitamin D more than the normal range is not recommended. [31:00] Vitamin D taken as a medication instead of a supplement. [31:35] Safe and average number of taking different supplements containing vitamin D. [33:58] Closing statement with Dr. Deva Boone. [34:35] Is there a topic you'd like to hear?   For more details about Dr. Deva Boone, visit her website www.devaboone.com or connect with her through these platforms:   Facebook: https://www.facebook.com/deva.boone  LinkedIn: https://www.linkedin.com/in/deva-boone-md-mba-95a31983/  Twitter: @DevaBoone Topic references:  https://parathyroidpeeps.com/2019/04/17/confused-about-vitamin-d-supplementation-in-relation-to-parathyroid-disease-expert-parathyroid-surgeon-dr-boone-explains/    https://www.parathyroidqanda.com/question/low-vitamin-d-but-normal-calcium-levels   https://www.inspire.com/groups/parathyroid/discussion/ask-the-expert-parathyroid-expert-and-surgeon-dr-deva-boone-aug-3-7/   https://www.southwestparathyroid.com/about   https://www.healthgrades.com/physician/dr-deva-boone-ggyws    You can check out her articles and learn more about Vitamin D: Vitamin D, part 1: https://www.devaboone.com/post/vitamin-d-part-1-back-to-basics Vitamin D, part 2: https://www.devaboone.com/post/vitamin-d-part-2-shannon-s-story Vitamin D, part 3: https://www.devaboone.com/post/vitamin-d-part-3-the-evidence  Vitamin D and Covid: https://www.devaboone.com/post/vitamin-d-and-covid Physiology of Vitamin D Resources:   Christakos S, Dhawan P, Verstuyf A, Verlinden L, Carmeliet G. “Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects”. Physiol Rev. 2016;96(1):365-408. https://doi.org/10.1152/physrev.00014.2015 Bikle DD. “Vitamin D metabolism, mechanism of action, and clinical applications.” Chem Biol. 2014;21(3):319-329. https://doi.org/10.1016/j.chembiol.2013.12.016   Randomized controlled trials of Vitamin D Resources:   VITAL trial Manson JE, Cook NR, Lee IM, et al. “Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease.” N Engl J Med. 2019;380(1):33-44.  ViDA (Vitamin D Assessment) Trial Scragg  R, Stewart  AW, Waayer  D,  et al.  “Effect of monthly high-dose vitamin D supplementation on cardiovascular disease in the vitamin D assessment study : a randomized clinical trial”.  JAMA Cardiol. 2017;2(6):608-616.  RECORD trial follow-up study Avenell A, MacLennan GS, Jenkinson DJ, et al. “Long-Term Follow-Up for Mortality and Cancer in a Randomized Placebo-Controlled Trial of Vitamin D3 and/or Calcium” (RECORD Trial), J Clin Endo & Met, Volume 97, Issue 2, 1 February 2012, Pages 614–622.   RECORD Trial Grant AM, Avenell A, Campbell MK, et al. “Oral vitamin D3 and calcium for secondary prevention of low-trauma fractures in elderly people” (Randomised Evaluation of Calcium Or vitamin D, RECORD): a randomised placebo-controlled trial. Lancet. 2005;365(9471):1621-1628.  VITAL-BONE Trial LeBoff MS, Chou SH, Murata EM, et al. “Effects of Supplemental Vitamin D on Bone Health Outcomes in Women and Men in the VITamin D and OmegA-3 TriaL (VITAL)”. J Bone Miner Res. 2020;35(5):883-893. D2d Trial Pittas AG, Dawson-Hughes B, Sheehan P, et al. Vitamin D Supplementation and Prevention of Type 2 Diabetes. N Engl J Med. 2019;381(6):520-530.  VIOLET (Vitamin D to Improve Outcomes by Leveraging Early Treatment) trialNational Heart, Lung, and Blood Institute PETAL Clinical Trials Network, Ginde AA, Brower RG, et al. “Early High-Dose Vitamin D3 for Critically Ill, Vitamin D-Deficient Patients”. N Engl J Med. 2019;381(26):2529-2540. List of significant meta-analyses on Vitamin D:   Zhang Y, Fang F, Tang J, et al. “Association between vitamin D supplementation and mortality: systematic review and meta-analysis”. BMJ. 2019;366:l4673. Bjelakovic G, Gluud LL, Nikolova D, et al. “Vitamin D supplementation for prevention of mortality in adults”. Cochrane Database Syst Rev. 2014;(1):CD007470.  Bjelakovic  G, Gluud  LL, Nikolova  D, et al. “Vitamin D supplementation for prevention of cancer in adults”. Cochrane Database of Systematic Reviews 2014, Issue 6. Art. No.: CD007469. Chung M, Lee J, Terasawa T, Lau J, Trikalinos TA. “Vitamin D with or without calcium supplementation for prevention of cancer and fractures: an updated meta-analysis for the US Preventive Services Task Force”. Ann Intern Med. 2011;155(12):827-838.   Avenell A, Mak JC, O'Connell D. “Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men”. Cochrane Database Syst Rev. 2014;4:CD000227. Jolliffe DA, Greenberg L, Hooper RL, et al. “Vitamin D supplementation to prevent asthma exacerbations: a systematic review and meta-analysis of individual participant data” [published correction appears in Lancet Respir Med. 2018 Jun;6(6):e27]. Lancet Respir Med. 2017;5(11):881-890. Martineau AR, Jolliffe DA, Greenberg L, et al. “Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis”. Health Technol Assess. 2019;23(2):1-44.   What did you learn about today's topic? Let us know by leaving a review! Visit these links to learn more: https://www.drchristianson.com/ Dr. Christianson on Facebook| (http://www.facebook.com/DrAlanChristianson/ Dr. Christianson on Instagram (http://www.instagram.com/dralanchristianson/)   Subscribe for more Medical Myths, Legends, & Fairytales: Apple Podcasts (https://podcasts.apple.com/us/podcast/medical-myths-legends-fairytales/id1467232418) Spotify (https://open.spotify.com/show/0HaZ75TpOCazsRQSG0AOFs) YouTube (https://www.youtube.com/user/Alannmd/videos)  

BASICS Scotland Podcast
James Hale - Permissive Hypotension

BASICS Scotland Podcast

Play Episode Listen Later Oct 18, 2021 38:29


James clarifies what the process of permissive hypotension is and how and why to use it as a temporary management strategy.    Top 3 tips:   1.    Try not to think about a specific number in these patients but look at the bigger picture. Assess for multipl