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E o Petit Saint-Germain se deu mal na nova Champions. Esqueci de dar REC no inicio da Live então começa após o bom dia, não assustem. Abrs!
Le Journal en français facile du mardi 14 mai 2024, 18h00 à Paris.Retrouvez votre épisode avec la transcription synchronisée et des exercices pédagogiques pour progresser en français : https://rfi.my/AbRS.A
En este episodio de Amigos TIC, Ricardo Triana, Director ejecutivo del CEA y Humberto Salazar, director de operaciones LATAM de ABRS, nos cuentan sobre las oportunidades que tiene Colombia con su talento a la hora de participar y emprender en las investigaciones de nuevos medicamentos, vacunas, etc. Escucha este episodio para conocer más. ¡No te lo pierdas!00:00 Amigos Tic 04:05 Ricardo Triana, Director ejecutivo del CEA04:15 Humberto Salazar, director de operaciones LATAM de ABRS05:12 ¿Qué hacen en ABRS?08:12 ¿Qué está pasando en Colombia con el nivel de investigación y de oferta?09:29 ¿Es público o privado?12:07 ¿Qué tipo de talento se necesita?15:20 ¿Qué oportunidades hay para los emprendedores?17:14 ¡Ojo al dato! con Santiago Pinzón23:07 ¿Cómo está Colombia frente a otros países?27:43 ¿Qué cantidad de mujeres participan?30:53 ¿Qué libros o qué pódcast leen?
En este episodio de Amigos TIC, Ricardo Triana, Director ejecutivo del CEA y Humberto Salazar, director de operaciones LATAM de ABRS, nos cuentan sobre las oportunidades que tiene Colombia con su talento a la hora de participar y emprender en las investigaciones de nuevos medicamentos, vacunas, etc. Escucha este episodio para conocer más. ¡No te lo pierdas!00:00 Amigos Tic 04:05 Ricardo Triana, Director ejecutivo del CEA04:15 Humberto Salazar, director de operaciones LATAM de ABRS05:12 ¿Qué hacen en ABRS?08:12 ¿Qué está pasando en Colombia con el nivel de investigación y de oferta?09:29 ¿Es público o privado?12:07 ¿Qué tipo de talento se necesita?15:20 ¿Qué oportunidades hay para los emprendedores?17:14 ¡Ojo al dato! con Santiago Pinzón23:07 ¿Cómo está Colombia frente a otros países?27:43 ¿Qué cantidad de mujeres participan?30:53 ¿Qué libros o qué pódcast leen?
Credits: 0.50 AMA PRA Category 1 Credits™, 0.50 ABIM MOC or 0.65 AANP, including 0.65 AANP Pharm CME/CE Information and Claim Credit: https://www.pri-med.com/online-cme-ce/Podcast/acute-bacterial-rhinosinusitis Overview: In this 30-minute podcast tailored for medical professionals, navigate the nuances of Acute Bacterial Rhinosinusitis (ABRS) as expert faculty discuss differentiating symptoms from acute rhinosinusitis. Gain practical insights on constructing effective treatment plans for ABRS in adults and acute bacterial sinusitis in pediatric populations, offering valuable guidance for appropriate antibiotic use in these scenarios. Stay informed and enhance your clinical decision-making skills in managing these common conditions. Guest: Danielle Hebert, DNP, MBA, ANP-BC
A 21 year-old woman with a 15 year history of asthma. presents with acute bacterial rhinosinusitis; she is without fever and in no acute distress. Her current medications include an ICS/LABA inhaler for reliever and prevention asthma therapy, and a LNG-IUD for contraception. She also reports being told by her parents that she has penicillin allergy, and states, “I had a pink rash on my face and body for a few days when I took penicillin at around 3 or 4 years-old.” In considering ABRS antimicrobial therapy for this patient, the preferred treatment option would be: A. CefpodoximeB. AzithromycinC. AmoxicillinD. Trimethoprim-sulfamethoxazole---YouTube: https://www.youtube.com/watch?v=V6a_DYT3KEg&list=PLf0PFEPBXfq592b5zCthlxSNIEM-H-EtDVisit fhea.com to learn more!
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.06.547961v1?rss=1 Authors: Wetekam, J., Hechavarria, J. C., Lopez-Jury, L., Gonzalez-Palomares, E., Koessl, M. Abstract: Deviance detection describes an increase of neural response strength caused by a stimulus with a low probability of occurrence. This ubiquitous phenomenon has been reported for multiple species, from subthalamic areas to auditory cortex. While cortical deviance detection has been well characterised by a range of studies covering neural activity at population level (mismatch negativity, MMN) as well as at cellular level (stimulus-specific adaptation, SSA), subcortical deviance detection has been studied mainly on cellular level in the form of SSA. Here, we aim to bridge this gap by using noninvasively recorded auditory brainstem responses (ABRs) to investigate deviance detection at population level in the lower stations of the auditory system of a hearing specialist: the bat Carollia perspicillata. Our present approach uses behaviourally relevant vocalisation stimuli that are closer to the animals' natural soundscape than artificial stimuli used in previous studies that focussed on subcortical areas. We show that deviance detection in ABRs is significantly stronger for echolocation pulses than for social communication calls or artificial sounds, indicating that subthalamic deviance detection depends on the behavioural meaning of a stimulus. Additionally, complex physical sound features like frequency- and amplitude-modulation affected the strength of deviance detection in the ABR. In summary, our results suggest that at population level, the bat brain can detect different types of deviants already in the brainstem. This shows that subthalamic brain structures exhibit more advanced forms of deviance detection than previously known. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Come on over and stay a while. A long while. That's right, we're talking about one of the fall's horror phenoms, BARBARIAN on Kill By Kill!! And don't worry, we go spoiler free to start before we get deep into this remarkable flick. Along the way, we talk about the ABRs, why using your expectations against you is the ultimate flex, compare and contrast cinemas' many bad listeners, the convenience of pre-fab murder basements, and celebrate the connection between comedy and horror. All this, plus a smashing edition of Choose Your Own Deathventure, and find the film's truest allegory: dating in 2022. Come for the night, stay forever with us, won't you? Never fear - new episodes of Kill By Kill are made available every other Friday! Dish By Dish: A Hannibal Rewatch on the Fridays in-between. Our linker.ee Our TeePublic shop for killer merch is right here: https://www.teepublic.com/stores/kill-by-kill-podcast?utm_campaign=18042&utm_medium=affiliate&utm_source=Kill%2BBy%2BKill%2Bpodcast%2B Have something to say? Find us on Twitter @KillByKillPod Join the conversation about any episode on the Facebook Group! Follow us on IG @killbykillpodcast Check out the films we've covered & what might come soon on Letterboxd! Get even more episodes exclusively on Patreon! Follow our station on vurbl: https://vurbl.com/station/2bdTISeI3X/ Artwork by Josh Hollis: joshhollis.com Kill By Kill theme by Revenge Body. For the full-length version and more great music, head to revengebodymemphis.bandcamp.com today!
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.10.14.512309v1?rss=1 Authors: Shan, T., Cappelloni, M. S., Maddox, R. K. Abstract: Music and speech are two sounds that are unique to human beings and encountered in daily life. Both are transformed by the auditory pathway from an initial acoustical encoding to higher level cognition. Most studies of speech and music processing are focused on the cortex, and the subcortical response to natural, polyphonic music is essentially unstudied. The goal of this study was to compare the subcortical encoding of music and speech using the auditory brainstem response (ABR). While several methods have recently been developed to derive the ABR to continuous speech, they are either not applicable to music or give poor results. In this study, we explored deriving the ABR through deconvolution using three regressors: 1) the half-wave rectified stimulus waveform, 2) the modeled inner hair cell potential, and 3) the auditory nerve model firing rate (ANM), where the latter two were generated from a computational auditory periphery model. After quantitatively comparing the three regressors, we found the ANM regressor yields robust and interpretable ABR waveforms to diverse genres of music and multiple types of speech stimuli. We then used the ANM-derived ABRs to compare the subcortical responses to music and speech and found that they are highly similar in morphology. We further investigated cortical responses using the same deconvolution method, and found the responses there were also quite similar, which was unexpected based on previous studies. Our study first developed approach that can be used to investigate subcortical encoding and processing for both natural speech and music with the potential for use in cortical encoding. Based on that, we concluded that when accounting for acoustical differences' nonlinear effects on peripheral encoding, the derived music and speech brainstem responses are highly correlated. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Hoy en "Mundo Rural" nos acercamos a la PAC en nuestro espacio semanal con la presidenta del Fondo Español de Garantía Agraria, María José Hernández. Con ella conocemos las últimas noticias en torno a la política agraria común y le hacemos llegar nuestras dudas. En esta ocasión hablamos de las regiones ABRS. Escuchar audio
El ministro de Agricultura, Pesca y Alimentación, Luis Planas, aseguraba el pasado viernes que el volumen de stock de enlace de aceite de oliva permite dar tranquilidad y seguridad a los consumidores, y que en ningún caso va a haber problemas de abastecimiento de este producto en todas sus categorías. Ha reiterado que pese a que Ucrania es el principal exportador de aceite de girasol a España, la interrupción del suministro por la invasión rusa y la situación de guerra no va a crear problemas de abastecimiento de grasas vegetales en nuestro país. De ello hemos hablado esta mañana con Alicia Hernández, responsable de la sectorial del aceite en Aragón. En #Agricultura2030DPC seguimos explicando el documento publicado por el Fondo Español de Garantía Agraria en el que hace algunas precisiones sobre la futura ayuda básica a la renta para la sostenibilidad (ABRS), que sustituirá al pago básico actual a partir del 1 de enero de 2023, cuando entre en vigor la reforma de la PAC. El sector del vino español con denominación de origen encara el futuro con optimismo, tras el fuerte impacto que supusieron para la actividad de las bodegas las restricciones impuestas por la pandemia especialmente en el canal horeca. Así se puso de manifiesto en la XXIX Asamblea General de la Conferencia Española de Consejos Reguladores Vitivinícolas (CECRV), que se celebró este viernes en el Museo del Vino de la Denominación de Origen Campo de Borja. La uva tempranillo, con 202.917 de hectáreas, ha desbancado por primera vez a la airén (200.084 hectáreas) como la variedad de vinificación más cultivada en España, según ha informado el Ministerio de Agricultura, Pesca y Alimentación (MAPA). Aragón (37.828 ha). Hoy ha estado en Aragón Radio Eduardo Ibáñez, presidente de la Denominación De Origen Campo de Borja. En #AguayregadiosdeAragónDPC, nos ha acompañado Isabel Bombal, directora General de Desarrollo Rural, Innovación y Formación Agroalimentaria, porque el Ministerio de Agricultura, Pesca y Alimentación sacaba a consulta pública el pasado miércoles el proyecto de real decreto de creación de la mesa y el observatorio del regadío. El Campus de Huesca de la Universidad de Zaragoza acogerá la tercera edición de la ‘Jornada de almendro y pistacho en el Valle del Ebro'. El aumento de las zonas de cultivo, la celeridad en los cambios en su manejo, así como las nuevas exigencias y evolución del mercado plantean novedades constantes en este sector agrario. Especialistas de distintas comunidades autónomas explicarán las estrategias desarrolladas en cada territorio. Lo hemos avanzado con sus organizadores.Marcos Clavel, director del Centro Río Gállego, nos ha explicado cómo avanza la puesta en marcha de un programa de formación para empleo dedicado a la agroecología. A partir del 1 de marzo aquellos que estén interesados en la agricultura ecológica van a tener la oportunidad de apuntarse a cualquiera de los 23 cursos que están dentro del Programa Formativo en Agroecología impulsado por Zaragoza Dinámica En #AragónsecomeDPC hemos conocido y entrado en una cueva para probar el Queso de Cerler.
La balanza comercial entre España y Ucrania es deficitaria para nuestro país, con un saldo negativo que supera los 600 millones. Y los cereales son la categoría más importada. Le compramos a Ucrania aproximadamente el 30% del maíz, y el 60% del aceite de girasol, adquiridos en el exterior. Sobre cómo influye en las cotizaciones y precios hemos comenzado hablando esta mañana con Miguel Ángel Bergés, presidente de la Lonja de Lérida En #Agricultura2030DPC seguimos explicando el documento publicado por el Fondo Español de Garantía Agraria en el que hace algunas precisiones sobre la futura ayuda básica a la renta para la sostenibilidad (ABRS), que sustituirá al pago básico actual a partir del 1 de enero de 2023, cuando entre en vigor la reforma de la PAC. Mañana se pone en marcha la Escuela de Pastores. El centro La Estiva ha recibido solicitudes de todo el país, más del doble de las que puede atender, demostrando que todavía existe interés por este oficio, y sobre todo por formarse en él. Esta mañana nos han acompañado Roberto Serrano, alcalde de San Juan de Plan, y Jesús Huertas, uno de los alumnos procedente de Madrid. El próximo martes se conmemora el Día de la Mujer. La inclusión de la perspectiva de género en la Política Agraria Común (PAC) se traducirá en más facilidades para la incorporación de las mujeres a la actividad agraria, más ayudas, más formación y mayor facilidad para la realización de inversiones. Para hablar de ello y de cuál es la situación de la Titularidad Agraria compartida en Aragón ha estado en De puertas al campo MariLuz Hernández, profesora titular del Departamento de Geografía y Ordenación del Territorio de la Universidad de Zaragoza. En #AguayregadiosdeAragónDPC, analizamos con Andrés del Campo, presidente de FENACORE, la puesta en marcha el pasado viernes por parte del Ministerio de Agricultura de la Mesa de la Sequía y hemos repasado las fechas para el inicio de las campañas de riego en Aragón. Esta semana tenía lugar en el CITA la presentación de las nuevas selecciones de almendros más tolerantes a enfermedades, injertadas en el nuevo portainjertos 'Pilowred', resistente a nematodos y dirigido a nuevos sistemas de cultivo, así como la nueva variedad de esta planta, 'Felama'. La responsable del grupo de mejora genética del almendro e investigadora de Ciencia Vegetal, María José Rubio, nos ha acompañado hoy para explicarnos esas particularidades. Pilar Fernández, coordinadora del curso de Agroecología del Ayuntamiento de Zaragoza, nos explicará la puesta en marcha de un programa de formación para empleo dedicado a la agroecología. A partir del 1 de marzo aquellos que estén interesados en la agricultura ecológica van a tener la oportunidad de apuntarse a cualquiera de los 23 cursos que están dentro del Programa Formativo en Agroecología impulsado por Zaragoza Dinámica En #AragónsecomeDPC, nos hemos marchado hasta Calatayud para probar una hamburguesa de nombre 'Montañas de Aragón', finalista en el Concurso a la Mejor Hamburguesa Artesana de España, organizado en el marco de la Feria Meat Attraction de Madrid.
La balanza comercial entre España y Ucrania es deficitaria para nuestro país, con un saldo negativo que supera los 600 millones. Y los cereales son la categoría más importada. Le compramos a Ucrania aproximadamente el 30% del maíz, y el 60% del aceite de girasol, adquiridos en el exterior. Sobre cómo puede continuar influyendo la guerra hemos comenzado hablando esta mañana con Marcos Martínez, presidente de la Asociación de Comercio de Cereales y Oleaginosas de España Un conflicto que también afecta al sector hortofrutícola aragonés en la exportación de productos como el ajo, la nectarina y el melocotón. Cifras que hemos valorado con Agustín Sánchez, secretario técnico de Fedefruta Aragón. En #Agricultura2030DPC hemos explicado el documento publicado esta semana por el Fondo Español de Garantía Agraria en el que hace algunas precisiones sobre la futura ayuda básica a la renta para la sostenibilidad (ABRS), que sustituirá al pago básico actual a partir del 1 de enero de 2023, cuando entre en vigor la reforma de la PAC. La Red Arax presentaba esta semana datos de los cultivos de verano: soja, maíz, alfalfa y arroz. Ha sido Miguel Gutiérrez, jefe de la Unidad de Cultivos Herbáceos del Centro de Transferencia Alimentaria de Aragón el que nos ha explicado todos los detalles. Borja acogerá a partir del 10 de marzo la reunión nacional de los Consejos Reguladores del Vino. Los detalles del encuentro los hemos conocido con Eduardo Ibáñez, presidente de la DO Campo de Borja y en #AguayregadiosdeAragónDPC nos hemos acercado hoy hasta las Comunidaddes de Regantes de Riegos del Altoaragón y el Canal de Aragón y Cataluña en una semana en la que hemos conocido ya las fechas para el inicio de las campañas de riego. El presidente de la Diputación Provincial de Huesca entregaba el viernes al científico Federico Fillat el XXIV Galardón Félix de Azara, uno de los pioneros en la investigación sobre paisaje pirenaico y ganadería, y con este premio se reconoce su defensa, divulgación y didáctica de la ganadería extensiva como una de las señas de identidad de la provincia altoaragonesa. Fillat nos ha acompañado esta mañana en Aragón Radio. Hemos contado la puesta en marcha de un programa de formación para empleo dedicado a la agroecología. A partir del 1 de marzo aquellos que estén interesados en la agricultura ecológica van a tener la oportunidad de apuntarse a cualquiera de los 23 cursos que están dentro del Programa Formativo en Agroecología impulsado por Zaragoza Dinámica.En #AragónsecomeDPC, nos hemo marcharemos hasta el Vallde del Manubles para probar el licor de cerezas ‘A Zofra'.
It would be hard to find any health practitioner - traditional, functional, or otherwise - who doesn’t acknowledge the importance of consuming omega-3 fatty acids. Supplements in the form of fish oil or krill oil are widely recommended and consumed, and come with claims of cardiovascular disease prevention, cognitive benefits, and anti-inflammatory properties. But is it really a good idea to get your omega-3s in a gel cap rather than from food? And do they really do everything the media would have you believe? On this podcast, NBT Scientific Director Megan Hall and I discuss omega-3 fatty acids: what they are, what they’re good for, and the best ways to get them. Megan outlines the different types of omega-3 and explains why some are better than others. She also explains why some health claims are overblown, and why buying fish oil supplements may not be the best health strategy. Be sure to follow along with Megan’s outline for this podcast. Here’s the outline of this interview with Megan Hall: [00:04:30] Blood flow restriction (BFR) training; Podcast: Blood Flow Restriction Training for Improved Strength, Performance, and Healthspan with Dr Jim Stray-Gundersen MD. [00:04:51] Podcast: Wired to Run: Why Your Brain Needs Exercise, David Raichlen. [00:05:41] What are omega-3 fatty acids? [00:06:31] Picture of omega-3 fatty acids. [00:08:40] Finding omega-3s in the diet; Review: Saini, Ramesh Kumar, and Young-Soo Keum. "Omega-3 and omega-6 polyunsaturated fatty acids: Dietary sources, metabolism, and significance—A review." Life sciences 203 (2018): 255-267. [00:09:16] Poor conversion from ALA to EPA/DHA: Gerster, Helga. "Can adults adequately convert a-linolenic acid (18: 3n-3) to eicosapentaenoic acid (20: 5n-3) and docosahexaenoic acid (22: 6n-3)?." International journal for vitamin and nutrition research 68.3 (1998): 159-173. [00:10:56] Why EPA and DHA are important. [00:11:38] Conditions associated with inadequate omega-3 intake. [00:12:02] Whole foods vs. supplements; other micronutrients. [00:12:42] Krill oil vs. fish oil; Studies: 1. Ulven, Stine M., et al. "Metabolic effects of krill oil are essentially similar to those of fish oil but at lower dose of EPA and DHA, in healthy volunteers." Lipids 46.1 (2011): 37-46. 2. Schuchardt, Jan Philipp, et al. "Incorporation of EPA and DHA into plasma phospholipids in response to different omega-3 fatty acid formulations-a comparative bioavailability study of fish oil vs. krill oil." Lipids in health and disease 10.1 (2011): 1-7. 3. Maki, Kevin C., et al. "Krill oil supplementation increases plasma concentrations of eicosapentaenoic and docosahexaenoic acids in overweight and obese men and women." Nutrition research 29.9 (2009): 609-615. 4. Mödinger, Yvonne, et al. "Plasma kinetics of choline and choline metabolites after a single dose of SuperbaBoostTM krill oil or choline bitartrate in healthy volunteers." Nutrients 11.10 (2019): 2548. [00:16:59] Megan's outline for this podcast. [00:18:21] Algae-based omega-3 supplements. [00:19:40] Omega 6:3 ratio; Paper: Simopoulos, Artemis P. "The importance of the ratio of omega-6/omega-3 essential fatty acids." Biomedicine & pharmacotherapy 56.8 (2002): 365-379. [00:25:54] Should we be supplementing with grams of fish oil? Studies: 1. De Magalhães, João Pedro, et al. "Fish oil supplements, longevity and aging." Aging (Albany NY) 8.8 (2016): 1578. 2. Strong, Randy, et al. "Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer." Aging cell 15.5 (2016): 872-884. 3. López-Domínguez, José A., et al. "The influence of dietary fat source on life span in calorie restricted mice." Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences 70.10 (2015): 1181-1188. [00:27:42] No support for omega-3 (fish oil) in the prevention of cardiovascular disease; Meta-analysis: Aung, Theingi, et al. "Associations of omega-3 fatty acid supplement use with cardiovascular disease risks: meta-analysis of 10 trials involving 77 917 individuals." JAMA cardiology 3.3 (2018): 225-233. [00:29:12] Signs you're supplementing too much fish oil. [00:30:26] Podcast: How Oxidative Stress Impacts Performance and Healthspan [00:30:43] Elevated blood glucose omega-3 supplementation; Study: Friday, Karen E., et al. "Elevated plasma glucose and lowered triglyceride levels from omega-3 fatty acid supplementation in type II diabetes." Diabetes care 12.4 (1989): 276-281. [00:31:01] Immunosuppressive effects of supplementing omega-3s: Fenton, Jenifer I., et al. "Immunomodulation by dietary long chain omega-3 fatty acids and the potential for adverse health outcomes." Prostaglandins, Leukotrienes and Essential Fatty Acids 89.6 (2013): 379-390. [00:34:17] Stages of life when omega-3s are especially important. [00:34:48] Specialized pro-resolving mediators; STEM Talk podcast episode: David LeMay Talks About Countering Inflammation with SPMS. [00:35:31] DHA to mitigate traumatic brain injury; Study: Bailes, Julian E., and Vimal Patel. "The potential for DHA to mitigate mild traumatic brain injury." Military medicine 179.suppl_11 (2014): 112-116. [00:35:45] DHA for cognitive function and aging; Study: Weiser, Michael J., Christopher M. Butt, and M. Hasan Mohajeri. "Docosahexaenoic acid and cognition throughout the lifespan." Nutrients 8.2 (2016): 99. [00:37:20] omega-3s for athletic performance; Review: Gammone, Maria Alessandra, et al. "Omega-3 polyunsaturated fatty acids: benefits and endpoints in sport." Nutrients 11.1 (2019): 46. [00:38:54] omega-3s during pregnancy; Studies: Greenberg, James A., Stacey J. Bell, and Wendy Van Ausdal. "Omega-3 fatty acid supplementation during pregnancy." Reviews in obstetrics and Gynecology 1.4 (2008): 162; 2. Braarud, Hanne Cecilie, et al. "Maternal DHA status during pregnancy has a positive impact on infant problem solving: a Norwegian prospective observation study." Nutrients 10.5 (2018): 529. [00:39:44] Excess omega-3 consumption during pregnancy could be detrimental to offspring; Study: Church, M. W., et al. "Excess omega-3 fatty acid consumption by mothers during pregnancy and lactation caused shorter life span and abnormal ABRs in old adult offspring." Neurotoxicology and teratology 32.2 (2010): 171-181. [00:40:12] Testing: The Omega Index test; Framingham Heart Study: Harris, William S., et al. "Erythrocyte long-chain omega-3 fatty acid levels are inversely associated with mortality and with incident cardiovascular disease: The Framingham Heart Study." Journal of clinical lipidology 12.3 (2018): 718-727. [00:42:34] Bottom line: More may not be better. [00:43:09] SMASH fish - sardines, mackerel, anchovies, salmon, herring (also black cod), 3-4x/week. [00:49:30] Schedule a free 15 min call with Megan.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.20.258301v1?rss=1 Authors: Polonenko, M. J., Maddox, R. K. Abstract: The auditory brainstem is important for processing speech, yet we have much to learn regarding the contributions of different subcortical structures. These deep neural generators respond quickly, making them difficult to study during dynamic, ongoing speech. Recently developed techniques have paved the way to use natural speech stimuli, but the auditory brainstem responses (ABRs) they provide are temporally broad and thus have ambiguous neural sources. Here we describe a new method that uses re-synthesized "peaky" speech stimuli and deconvolution analysis of EEG data to measure canonical ABRs to continuous naturalistic speech of male and female narrators. We show that in adults with normal hearing, peaky speech quickly yields robust ABRs that can be used to investigate speech processing at distinct subcortical structures from auditory nerve to rostral brainstem. We further demonstrate the versatility of peaky speech by simultaneously measuring bilateral and ear-specific responses across different frequency bands. Thus, the peaky speech method holds promise as a powerful tool for investigating speech processing and for clinical applications. Copy rights belong to original authors. Visit the link for more info
Jake joins the boys to chat about his epic Bruins jersey collection, fills us in on what he has going on with his non-profit Heart Support, and shares an epic story about ABRs trip to the Grammys. Make sure you pick up a copy of August Burns Red new album "Guardians," which is out on Fearless Records April 3rd. August Burns Red-Defender August Burns Red-White Washed Free Throw-Motorcycle, No Motor?
This week we are joined by 4th year University of Ottawa student Zuhaib Mir who will be discussing Acute Bacterial Rhinosinusitis. This podcast was created as a collaborative effort between Surgery101, LearnENT, and the Canadian Society of Otolarygology-Head & Neck Surgery as part of a special series of topics on primary care otolaryngology. After this podcast you will be able to: Understand the importance of the topic Define Acute bacterial Rhinosinusitis and discuss the relevant anatomy Describe the risk factors associated Describe the clinical presentation and differential diagnosis Recommend treatment for ABRS, including complications and when you should refer to OHNS
This podcast highlights the updated clinical practice guideline on adult sinusitis that is published as an April 2015 supplement to Otolaryngology - Head and Neck Surgery, the official journal of the American Academy of Otolaryngology - Head and Neck Surgery (AAO-HNS) Foundation. In the first of two podcasts for this supplement, Editor in chief John Krouse is joined by lead author Richard Rosenfeld and co-author Richard Orlandi in discussing key findings from the guideline in the diagnosis and treatment of adults with symptoms of sinusitis. Sinusitis affects about 1 in 8 adults in the United States, resulting in more than 30 million annual diagnoses. The direct cost of managing acute and chronic sinusitis exceeds $11 billion per year, with additional expense from lost productivity, reduced job effectiveness, and impaired quality of life. More than 1 in 5 antibiotics prescribed in adults are for sinusitis, making it the fifth-most common diagnosis responsible for antibiotic therapy. Rhinosinusitis may be classified by duration as acute rhinosinusitis (ARS) if less than 4 weeks’ duration or as chronic rhinosinusitis (CRS) if lasting more than 12 weeks, with or without acute exacerbations. ARS may be classified further by presumed etiology, based on symptoms and time course, into acute bacterial rhinosinusitis (ABRS) or viral rhinosinusitis (VRS). Symptoms include purulent nasal discharge accompanied by nasal obstruction, facial pain/pressure/fullness, or both. Acute bacterial rhinosinusitis can be differentiated from acute viral rhinosinusitis if symptoms persist for at least 10 days without improvement or if symptoms worsen within 10 days after initial improvement. In addition, clinicians should not obtain radiographic imaging for uncomplicated acute rhinosinusitis. Furthermore, clinicians can consider watchful waiting without antibiotic treatment for uncomplicated acute sinusitis. Primary antibiotic therapy should include 5 to 10 days of amoxicillin with or without clavulate for most adults with sinusitis. These guidelines discuss additional recommendations and options for clinicians treating these adult patients with sinusitis. Click here to read the full article.
Afrobeta Bodega Radio returns with a very special mix by our sister Helen Ting (Kazakuta Records – Hong Kong). If music...
Afrobeta Bodega Radio returns with a deep and sexy mix courtesy of our brother, DjL from Vialocal Records. DjL’s musical...
This week Afrobeta Bodega Radio brings another great deep techy mix by our brother Haru of OndaSonora and 28’c all the way...
This week Afrobeta Bodega Radio brings another great deep dark techy mix by our brother Toto Chiavetta of Vialocal and Yoruba...
This week Afrobeta Bodega Radio brings you another incredible mix by Yoruba Records Dj/Producer Jacob Santo all the way from Santorini,...
This week Afrobeta Bodega Radio brings a great mixed set from our dear friend David Castellano all the way from the...
This week Afrobeta Bodega Radio returns with some serious heat to keep you going through this summer months all the...
This week afrobeta bodega returns with the heat all the way from Amsterdam, Netherlands by way of Denz Devarez the...
This week afrobeta bodega returns with some serious heat all the way from Lamia, Greece by way of Antonis Banousis aka...
This week afrobeta bodega returns with more heat from Boston’s own Dj/Producer K.C. Hallet. A veteran of the Boston house music...
This week afrobeta bodega returns with more heat welcoming back our brother Dj/Producer Aquabeat. A veteran of the NYC house music scene...
This week Afrobeta Bodega Radio brings you a great deep afro mix by Bond Jobe a Dj/Producer from South Africa....
Objective: Recent findings support the crucial role of microcirculatory disturbance and ischemia for hearing impairment especially after noise-induced hearing loss (NIHL). The aim of this study was to establish an animal model for in vivo analysis of cochlear microcirculation and hearing function after a loud noise to allow precise measurements of both parameters in vivo. Study Design: Randomized controlled trial. Setting: Animal study. Subjects and Methods: After assessment of normacusis (0 minutes) using evoked auditory brainstem responses (ABRs), noise (106-dB sound pressure level [SPL]) was applied to both ears in 6 guinea pigs for 30 minutes while unexposed animals served as controls. In vivo fluorescence microscopy of the stria vascularis capillaries was performed after surgical exposure of 1 cochlea. ABR measurements were derived from the contralateral ear. Results: After noise exposure, red blood cell velocity was reduced significantly by 24.3% (120 minutes) and further decreased to 44.5% at the end of the observation (210 minutes) in contrast to stable control measurements. Vessel diameters were not affected in both groups. A gradual decrease of segmental blood flow became significant (38.1%) after 150 minutes compared with controls. Hearing thresholds shifted significantly from 20.0 ± 5.5 dB SPL (0 minutes) to 32.5 ± 4.2dB SPL (60 minutes) only in animals exposed to loud noise. Conclusion: With regard to novel treatments targeting the stria vascularis in NIHL, this standardized model allows us to analyze in detail cochlear microcirculation and hearing function in vivo.