Podcasts about Troponin

Contributor: Taylor Lynch, MD Educational Pearls: How do we risk-stratify chest-pain patients? One option is the HEART score This score predicts a patient's 6-week risk of a major adverse cardiac event. Ex. Cath procedure, CABG, PCI, death H stands for History Ask 1) Was the patient diaphoretic? 2) Did they have nausea and/or vomiting? 3) Did the pain radiate down the right or left arm? 4) Was it exertional? Yes to one = one point. Two or more = two points. E stands for EKG One point for left ventricular hypertrophy, t-wave inversions, new bundle-branch blocks. No points for first degree AV block, benign early repolarization, or QT-prolongation Two points for ST-depression A stands for Age >65 gets two points 45-64 gets one point R stands for Risk factors Hypertension, hyperlipidemia, diabetes, obesity, family history, smoking, previous MI, previous CABG, stroke, peripheral arterial disease 1-2 risk factors get 1 point More than two risk factors gets two points T stands for Troponin 1-3x upper limit of normal gets one point >3x upper limit of normal gets two points This gives you a score between zero and ten 0-3 points, patients have a ~2% chance of an adverse event These patients likely go home 4-6 points, patients have a ~20% chance of an adverse event These patients get admitted or expedited outpatient stress test/echo 7-10 points, patients have a ~60% chance of an adverse event Admit and call cardiology. These patients likely get catheterized References Backus BE, Six AJ, Kelder JC, Bosschaert MA, Mast EG, Mosterd A, Veldkamp RF, Wardeh AJ, Tio R, Braam R, Monnink SH, van Tooren R, Mast TP, van den Akker F, Cramer MJ, Poldervaart JM, Hoes AW, Doevendans PA. A prospective validation of the HEART score for chest pain patients at the emergency department. Int J Cardiol. 2013 Oct 3;168(3):2153-8. doi: 10.1016/j.ijcard.2013.01.255. Epub 2013 Mar 7. PMID: 23465250. Laureano-Phillips J, Robinson RD, Aryal S, Blair S, Wilson D, Boyd K, Schrader CD, Zenarosa NR, Wang H. HEART Score Risk Stratification of Low-Risk Chest Pain Patients in the Emergency Department: A Systematic Review and Meta-Analysis. Ann Emerg Med. 2019 Aug;74(2):187-203. doi: 10.1016/j.annemergmed.2018.12.010. Epub 2019 Feb 2. PMID: 30718010. https://www.mdcalc.com/calc/1752/heart-score-major-cardiac-events Summarized by Jeffrey Olson, MS4 | Edited by Jorge Chalit, OMS4 Donate: https://emergencymedicalminute.org/donate/

In this episode, Dr. Valentin Fuster discusses a study showing that elevated cardiac troponin levels after intense exercise in middle-aged recreational athletes are common but not linked to hidden coronary artery disease. The findings raise important questions about the origin and significance of these elevations, highlighting the need for long-term follow-up.

AABP Executive Director Dr. Fred Gingrich reviews a paper published in The Bovine Practitioner with the first author Madeline Mancke from Kansas State University. The objective of this study was to determine potential associations between Cardiac Troponin I (cTnI) serum concentration of cattle at initial bovine respiratory disease (BRD) treatment with the risk of retreatment or mortality at 60 days. BRD is the most significant disease in beef cattle and is a major cause of morbidity and mortality. Developing prognostic tools may be valuable for managing individual cases. cTnI is a protein that is released into the circulatory system after myocardial damage and may be useful as a biomarker for prognostication of BRD cases. Mancke walks through the results of the paper which demonstrated that 8/318 samples had high cTnI levels and animals with high cTn1 concentrations had a significantly greater probability of not finishing the 60-day post-enrollment period. Cattle with high cardiac troponin concentrations at initial BRD treatment were more likely to have negative clinical outcomes but, in this study, very few animals had high cTnI levels. Mancke provides information about potential future research opportunities to better manage BRD cases in the feedyard.  The Bovine Practitioner is the peer-reviewed journal published by AABP. The journal publishes original research, case studies, review articles and case studies that are intended to provide information to the practicing cattle veterinarian. The journal is available open-access online and print volumes are available for purchase. There are no publication fees for authors and the peer review and submission process is managed online. Find the journal at this link.  Evaluation of cardiac troponin I as a predictor of clinical outcomes in cattle treated for bovine respiratory disease (BRD) in commercial feedyards. Bov Pract. 2025;59(1), 24-28. https://doi.org/10.21423/bpj20259053 

فیبریلاسیون دهلیزی و تروپونین

In this Nephrology episode, Dr.Samira Farouk discusses the nuances of AKI, why you should be trending Urine like you trend Troponin. Stay tuned to find out the final diagnosis! Session facilitator: Dr.Elena Storz Case Discussants: Dr.Douglas Farrell MD: Nephrology Fellow, Icahn School of Medicine at Mount Sinai Dr. Samira Farouk MD: Associate Professor of Medicine… Read More »Episode 389: Rafael Medina Subspecialty Series – Hypotension and Peaked T waves

Hosts Mitsuaki Sawano, MD, and co-host Satoshi Shoji, MD, welcome Kenji Inoue, MD, to discuss the DROP-Asian ACS study—a multicenter trial evaluating the 0/1-hour algorithm for chest pain assessment across 12 hospitals in five Asian countries presented as a Late Breaking Clinical Trial at the ACC.25. Dr. Inoue shares key findings from this cluster-randomized trial of nearly 4,000 patients, highlighting the algorithm's practicality in Asia's diverse healthcare settings. Despite regional differences, the 0/1-hour approach—requiring only two high-sensitivity troponin measurements—proved effective and accessible, even in low-resource environments. He also reflects on presenting at ACC, the importance of early preparation, and the growth that comes from taking on complex international research. Dr. Inoue encourages young clinicians to embrace challenges and actively engage with global networks for clinical research development.

A deep conversation about the beauty of the heart; physically and emotionally. Hear Erin's heartfelt story of her beloved sister and the heart complications that ended in her sudden passing. Learn the steps you can take to proactively care for your heart and the knowledge to equip you in the case of a heart attack or stroke, all while boldly advocating for yourself.And, it doesn't end there, our conversation dives into the emotional side of the heart and it's ancient connections that continue to serve us on our journey to “Know Thyself”.Follow Erin Moran on Instagram @LionessBossBabe and The American Heart Association Go Red for Women to learn more about heart health awareness all year round.—-------Here a few notes from our conversation:Signs and Symptoms of Stroke: F.A.S.T. (Facial Drooping, Arm Numbness/weakness, Slurred Speech, Time to call 9-1-1)If you feel as though you are having a heart attack, ask for the “differential diagnosis”, a D-dimer test, have your Troponin level measured, and bring an advocate with you if possible.Suggested books: "The Myth of Normal: Trauma, Illness and Healing in a Toxic Culture" by Daniel Mate' and Gabor Mate'ACEs (Adverse Childhood Experiences)The “Weighing of the Heart” scene, Ancient Kemet (Egypt) depicted in the  Book of Coming Forth By Day, found on papyrus scrolls.

Imagine if you could know years in advance that you're at risk for a certain illness. What if you had access to the tools and information to take action now to prevent it? In episode 209 of Eat Move Think, Dr. Peter Nord, Medcan's Chief Medical Officer, explores this topic.  Tune in to hear Dr. Nord explain: The role of genetics in predicting future health Medical advances that can help identify early risk factors and indicators What steps you can take now to improve your health into your later years What You Can Do Medcan's Annual Health Assessment is a critical first step to understanding your current health and risk factors. It consists of up to 15 screenings including the hs-Troponin test. For those who would like to take a deeper look at their genetic information, we offer our Enhanced Genetics Screening services including Whole Genome Sequencing. Learn More Annual Health Assessment: medcan.com/assess Enhanced Genetics Screening: medcan.com/genetics  

Troponin is a protein found in heart muscle that was a game changer when it came to diagnosing heart attacks and myocardial injury in the late 1990s. Three decades later, it is an invaluable test with widespread use throughout medicine. Troponin assays are venturing into their 5th generation with high-sensitivity and Point-Of-Care (POC) devices. However, there are important exceptions, caveats and pitfalls for doctors to know. This is the story of troponin. Our special guest: Our special guest is Dr Christina Trambas who is a chemical pathologist, Medical Director at St Vincent's Pathology and chair of the Royal College of Pathologists of Australiasia (RCPA) Troponin Working Party. This Medical Life podcast is available on all podcasting services and Spotify.See omnystudio.com/listener for privacy information.

In this week's replay episode from 2 years ago, we review the important topic of troponin levels in children. What is an abnormal high sensitivity troponin level in children and do the levels vary based upon the assay? What are the differences between high sensitivity troponin I and T levels? Are there differences between boys and girls? Why would using the 97.5%ile upper reference limit result in a more reliable 'line in the sand' in comparison with the more traditional, high sensitivity troponin level cut off of 99th%ile. These are amongst the questions we review with this week's author, Dr. J. Bill McEvoy, Professor of Preventive Cardiology at University of Galway, Ireland. DOI: 10.1161/CIRCULATIONAHA.122.063281

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances discusses a recently published original research paper on the association of Cardiac Troponin T with coronary atherosclerosis in asymptomatic primary prevention in people with HIV.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances discusses a recently published original research paper on STEMI, revascularization, and peak troponin by adverse pregnancy outcomes in women with myocardial infarction

In this episode of the Heart podcast, Digital Media Editor, Professor James Rudd, is joined by Dr Love Cyon from Stockholm, Sweden. They discuss his paper exploring the prognostic value of troponin levels in chest pain patients in the ED. If you enjoy the show, please leave us a podcast review at https://itunes.apple.com/gb/podcast/heart-podcast/id445358212?mt=2 or wherever you get your podcasts - it's really helpful. Link to published paper: https://heart.bmj.com/content/early/2024/06/07/heartjnl-2024-323913  

Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief

Commentary by Dr. Candice Silversides

Dr. Pregerson reviews the ACC Expert Consensus Decision Pathway on the Evaluation and Disposition of Acute Chest Pain by focusing on high-sensitivity troponin, delta troponin, unstable angina, renal failure, and baseline troponin, only in this month's podcast. Read more in the Show Notes.

Commentary by Dr. Valentin Fuster

Pre-Hospital Rule-Out of Non-ST-Segment Elevation Acute Coronary Syndrome by a Single Troponin Measurement: Final One-Year Outcomes of the ARTICA Randomised Trial (AHA 2023)

Our latest episode dissects three groundbreaking studies that are reshaping our understanding of the heart and its intricate connections to the body and mind.   STUDY #1: First, we explore the potential of high-sensitivity cardiac troponin I (hs-cTnI) in risk-stratifying patients with known coronary artery disease. While current guidelines don't yet recommend these tests, could there be untapped value in using troponin concentration as a preventive treatment guide? Join us as we explore the intriguing possibilities and implications presented in this study from the Journal of the American College of Cardiology. Wereski, R, Adamson, P, Daud, NSS, et al. 2023. High-sensitivity cardiac troponin for risk assessment in patients with chronic coronary artery disease. J Am Coll Cardiol. 6: 473–485. (https://doi.org/10.1016/j.jacc.2023.05.046)   STUDY #2: Next, we shift our focus to the brain-heart connection. Ever wondered about the cognitive repercussions of a myocardial infarction (MI)? This study from JAMA Neurology sheds light on the potential cognitive consequences of an MI.  Johansen, MC, Ye, W, Gross, A, et al. 2023. Association between acute myocardial infarction and cognition. JAMA Neurol. 7: 723–731. (https://doi.org/10.1001/jamaneurol.2023.1331)   STUDY #3: Third, we dive deep (pun intended!) into decompression illness. Certain divers might want to reconsider their next dive because a recent Annals of Internal Medicine study suggests a primary mechanism behind decompression illness that could change the way we perceive diving risks. What are the implications for those passionate about the deep blue? Lee, H-J, Lim, DS, Lee, J, et al. 2023. Decompression illness in divers with or without patent foramen ovale: A cohort study. Ann Intern Med. 7: 934–939. (https://doi.org/10.7326/M23-0260)   Don't miss out on these captivating discussions. Listen in to stay at the forefront of cardiology insights and to satiate your curiosity about these studies' findings. We promise, it's a heartbeat away from being your favorite episode yet! For show notes, visit us at https://www.medmastery.com/podcasts/cardiology-podcast.

In this episode, Our guest host Avromi talks about pushing GDMT via the STRONG-HF trial. We also start our MHP2023 recap series with some pearls from Dr. Zier's cardiology update session. | 00.33 - TOC | | 01.19 - MHP2023 Afib updates | AFFIRM 2002 (rate and rhythm non-inferior) EAST-AFNET 4 - using dofetilide CABANA - using ablation and evaluating HF patients ESC commentary - impact of AFFIRM and changes in management to today | 03.04 - Guest host Avromi and STRONG-HF [Lancet 2022]. Click here for a slide deck overview of the study. | | 08.49 - MHP2023 high-sensitivity Troponin and AMI management | COMPASS-MI - using hs-cTnT for early rule out PLATO (lower primary outcome w/ ticagrelor v clopidogrel, equivalent bleeding), TRITON-TIMI 38 (lower primary outcome w/ prasugrel v clopidogrel, equivalent bleeding), ISAR-REACT 5 (lower mortality w/prasugrel v ticagrelor w/ similar bleeding risks) RAPID CABG (NOT PEER REVIEWED YET)- similar rates of bleeding waiting off ticagrelor 2-3d vs 5-7d REVERSE-IT - bentracimab for reversal of ticagrelor 2023 ESC Guidelines for ACS | 11.17 - Closing | [The appearance of external hyperlinks does not constitute endorsements by UCSF of the linked websites, or the information, products, or services contained therein. UCSF does not exercise any editorial control over the information found therein, nor does UCSF make any representation of their accuracy or completeness. All information contained in this episode are the opinions of the respective speakers and not necessarily the views their respective institutions or UCSF, and is only provided for information purposes, not to diagnose or treat.] png image from pngtree.com

Calling the cardiologist unnecessarily from the ED for every little raised troponin is one of my pet peeves. In this episode, I discuss what troponins are and what are the conditions in which they shoot up. Don't just believe me. Do your own research too. You can go through some of the following literature - 1. https://pubmed.ncbi.nlm.nih.gov/20685679/ 2. https://pubmed.ncbi.nlm.nih.gov/15136402/ 3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554225/ 4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860726/ 5. https://pubmed.ncbi.nlm.nih.gov/15736582/ 6. https://pubmed.ncbi.nlm.nih.gov/12460876/ 7. https://pubmed.ncbi.nlm.nih.gov/9510880/ 8. https://pubmed.ncbi.nlm.nih.gov/22105197/ 9. https://pubmed.ncbi.nlm.nih.gov/26346942/

We now have a blood test that tells us with absolute certainty whether or not someone is having a heart attack. https://dralo.net/links

Commentary by Dr. Valentin Fuster

In this episode of Heart Doc VIP with Dr. Joel Kahn, you'll discover recent groundbreaking scientific studies that are closely tied to your well-being and lifespan. Dr. Kahn delves into the importance of requesting a high-sensitivity troponin blood test, a key measure that can provide insights into your potential risk for heart conditions and overall longevity. Available at Quest and various other labs, troponin is a vital biomarker that complements BNP and galectin-3 as indicators of heart failure. Furthermore, Dr. Kahn is excited to announce a 6-week online seminar and interactive Q&A, commencing in August. Discover more and register for this invaluable opportunity to engage with a heart health expert at Dr. Joel Kahn's Whole Heart Masterclass.

Commentary by Dr. Valentin Fuster

In dieser Podcastfolge sprechen wir über den Laborwert Troponin und klären die Frage, ob es möglich ist mit dem Troponin-Wert einen Myokardinfarkt zu diagnostizieren...? kostenloser Blog https://natuerlich-elli.de/blog-heilpraktikeranwaerter/ Unverbindliche Anmeldung Prüfungsvorbereitung https://natuerlich-elli.de/hppruefung/ Folge mir auf Instagram: https://www.instagram.com/natuerlich_elli/ Komm in unsere kostenlose FB-Lerngruppe: https://www.facebook.com/groups/natuerlichelli (bearbeitet)

Overview Troponin I Normal value range Pathophysiology Special considerations Elevations in lab values Nursing Points General Normal value range Typically, less than 0.035 ng/mL or less Can vary among institutions Has to be greater than the 99th percentile Pathophysiology Troponin is released during myocardial cell damage Decreased perfusion causes myocardial cell damage Causes of myocardial cell damage Myocardial infarction Demand ischemia Cardiogenic ACS Noncardiogenic Sepsis Renal failure Extreme exercise Special considerations Submitted in green top tube Value peak Detection 6-12 hours after acute injury Peaks 24 hours after injury Can stay elevated for a week Knowing patient history is critical Increased values Any elevated value is typically considered critical Acute elevations warrant immediate investigation Typically PCI (percutaneous coronary intervention)/Angiography and EKG to rule out MI or ACS (acute coronary syndrome) Other elevations CABG Extreme exercise End Stage Renal Failure Assessment Assess for: Acute chest pain Symptoms of MI Nausea Vomiting Angina in any form Reflux (especially in women) Therapeutic Management EKG Angiography or PCI Management of non-cardiogenic etiology Nursing Concepts Lab Values Perfusion Patient Education Educate patient on keeping history of elevated levels or cardiac disease for future reference Educate patient on duration of elevated troponin levels, post injury

Commentary by Dr. Valentin Fuster

Commentary by Dr. Valentin Fuster

In this week's episode we review the important topic of troponin levels in children. What is an abnormal high sensitivity troponin level in children and do the levels vary based upon the assay? What are the differences between high sensitivity troponin I and T levels? Are there differences between boys and girls? Why would using the 97.5%ile upper reference limit result in a more reliable 'line in the sand' in comparison with the more traditional, high sensitivity troponin level cut off of 99th%ile. These are amongst the questions we review with this week's author, Dr. J. Bill McEvoy, Professor of Preventive Cardiology at University of Galway, Ireland. DOI: 10.1161/CIRCULATIONAHA.122.063281

Get a free nursing lab values cheat sheet at NURSING.com/63labs   What is the Lab Name for Troponin I (cTNL) Lab Values? Troponin I   What is the Lab Abbreviation for Troponin I? cTNL   What is Troponin I in terms of Nursing Labs? Troponins are proteins that initiate contraction of muscle fibers. Troponin I (cTNL) is specific to heart muscle. Troponin levels stay elevated for a week after muscle damage before returning to normal.   What is the Normal Range for Troponin I? There is a wide range of normal values among varying institutions and texts with regard to Troponin I. It is essential to verify institutional norms. < 0.035 ng/mL   What are the Indications for Troponin I? Evaluating damage to heart muscle Diagnose a Myocardial Infarction (MI)   What would cause Increased Levels of Troponin I? Heart damage Myocardial Infarction (MI)   What would cause Decreased Levels of Troponin I? N/A

Justin Harris is the owner of Troponin Nutrition and 1st Detachment supplements. He specializes in customized training and performance nutrition. He works with the world's top bodybuilders and powerlifters to take their strength and physiques to the next level. Justin is an accomplished academic with a masters degree in atomic physics an undergraduate in kinesiology along with an exercise science degree. On top of exceptional degrees he has put his knowledge to the test in the trenches. He was the 2004 Mr. Michigan, Super Heavyweight Champion for the 2006 Jr. USA's, 2007 and 2008 APF Michigan Powerlifting Champion totaling elite both years. Justin has published two books along with multiple comprehensive ebooks along with countless articles and podcasts. https://1stdetachment.com/https://www.troponinnutrition.com/https://instagram.com/troponin_nutrition?igshid=YmMyMTA2M2Y=https://youtube.com/@platesandpancakes4593https://instagram.com/voodoo4power?igshid=YmMyMTA2M2Y=https://voodoo4ranch.com/To possibly be a guest or support the show email Voodoo4ranch@gmail.comhttps://www.paypal.com/paypalme/voodoo4ranch

A Novel Breakthrough In Wrist-Worn Transdermal Troponin-I-Sensor Assessment For Acute Myocardial Infarction

In this episode, as part of American Heart Month, we chat with Dr. Deborah Diercks at ACEP22 about the current landscape of ACS and troponin.

elitefts Limited Edition Apparel: https://www.elitefts.com/shop/apparel/limited-edition.html      Support and help the Podcast grow by Joining The Crew: https://glow.fm/davetatestabletalk/       Justin Harris takes a seat in this 169th podcast episode of Dave Tate's Table Talk.   Justin Harris is the owner of the customized training and performance nutrition company Troponin Nutrition and co-owner of 1st Detachment. He helps serious athletes who train hard by providing expert coaching and performance nutrition built on results. He holds a Master's degree in Atomic Physics with an undergraduate degree in Kinesiology.   As a top-level competitor, Justin was the: Overall winner of the 2004 Mr. Michigan Superheavyweight champion for the 2006 Jr. USAs 2007 and 2008 APF Michigan powerlifting champion, totaling “Elite” in both competitions 1st Detachment: https://1stdetachment.com/ Troponin Nutrition: https://www.troponinnutrition.com/ Justin's IG: https://www.instagram.com/troponin_nutrition/?hl=en       ABOUT THE HOST   Dave Tate is the founder and co-owner of elitefts.com. He is the author of twenty books and has logged more than 40,000 hours of training and consulting. Dave is married to elitefts co-owner Traci Arnold-Tate, and they reside in London, Ohio, with their two sons. Personal Credo: Live, Learn, Pass on™.   Dave's IG: https://www.instagram.com/underthebar/?hl=en     SPONSORS     Marek Health    Marek Health is the telehealth platform that connects customers to partnered providers focusing on hormone optimization and preventative medicine—offering self-service labs at great prices and guided optimization.     www.MarekHealth.com/tabletalk  Use Code Tabletalk for 10% off your first order. Also, check out the Table Talk Panel: www.MarekHealth.com/tabletalk         1st Detachment    1st Detachment (1D) is a veteran-founded, expert-formulated supplement company led by renowned coach Justin Harris and optimal living specialist Joe Miller. From a game-changing pre-workout to potent glucose disposal agents & industry-leading intra-workout, we've combined science with real-world experience to custom-formulate each product.   We are battle tested. Are you? Find your battle today!   Use code TABLETALK10 at checkout for 10% OFF your order.   https://1stdetachment.com/       Power Rack Strength CBD    Our CBD Isolate is derived from hemp, not Marijuana, and is 100% THC-FREE, with testing on the website for each batch. It won't get you high or make you fail a drug test.    Many law enforcement, fire department, military, and truck driver personnel use our products. For those who need to relax, struggle with sleep, or have achy muscles, CDB is a must-have, especially for athletes.    Use discount code: TABLETALK2023 - 35% off ANY order, no limit.  CBD: https://powerrackstrengthcbd.com     Gift of Injury: https://www.powerrackstrength.com/gift-of-injury/         elitefts   If you can put it in a gym bag or load weight on it, we have you covered.   https://www.elitefts.com/     Use Code TABLE TALK for 10% off your first elitefts order.     SUPPORT THE SHOW   All profits from elitefts Limited Edition Apparel, Table Talk Coffee, and Team elitefts Workouts, Programs, and Training eBooks support Dave Tate's Table Talk Podcast. Shop these elitefts items: https://www.elitefts.com/content/table-talk/   Support Dave Tate's Table Talk podcast by joining the crew.  https://glow.fm/davetatestabletalk/    elitefts Shop: https://www.elitefts.com/   elitefts IG: https://www.instagram.com/elitefts/

Many Coders tend to read a physician's note and make assumptions without first reading the coding guidelines. One particular entry, which is found in many admission notes is “elevated troponin”. An elevated troponin does not always mean that a heart attack has occurred, many many coders will leap to that conclusion before reviewing the documentation. […] The post Elevated troponin levels: may not be what you think! appeared first on Terry Fletcher Consulting, Inc..

Commentary by Dr. Valentin Fuster

In this month's EM Quick Hits podcast: Anand Swaminathan on GI balloon tamponade preparation and indications, Jesse McLaren on why troponin is rarely useful in SVT, Christina Shenvi on why we should not use the term "mechanical fall" in older patients, Nour Khatib & Jonathan Wallace on rural vertical vertigo case and Reuben Strayer on VAFEI - Video-Assisted Flexible Endoscopic Intubation for the anatomically challenging airway... The post EM Quick Hits 40 – GI Balloon Tamponade, SVT and Troponin, Falls in Older Patients, Vertical Vertigo, VAFEI Airway appeared first on Emergency Medicine Cases.

Contributor: Jared Scott, MD Educational Pearls: A study randomized 34 healthy patient to have their left anterior descending artery (LAD) occluded by balloon for 0, 15, 30, or 90 seconds   Subsequently,  cardiac troponins (cTns) and Copeptin were measured every 15 minutes for 3 hours, then every 30 minutes for the next 3 hours 5 conclusions were drawn: Copeptin is not a useful marker of cardiac ischemia  cTn may be detected after only 30 seconds of ischemia  cTn may be detected in a little as 15 minutes after ischemic event  After only 90 seconds of ischemia, cTn levels met threshold for MI  Troponin I is a better marker than troponin T as it rises faster and reaches a higher peak Patients very recent or very brief ischemic events may have elevated troponin in the ED References Árnadóttir Á, Pedersen S, Bo Hasselbalch R, et al. Temporal Release of High-Sensitivity Cardiac Troponin T and I and Copeptin After Brief Induced Coronary Artery Balloon Occlusion in Humans [published correction appears in Circulation. 2021 Jun 22;143(25):e1116]. Circulation. 2021;143(11):1095-1104. doi:10.1161/CIRCULATIONAHA.120.046574 Summarized by Kirsten Hughes, MS4 | Edited by John Spartz, MD, MPH & Erik Verzemnieks, MD   The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at https://emergencymedicalminute.org/cme-courses/ and create an account.  Donate to EMM today!

Overview Troponin I Normal value range Pathophysiology Special considerations Elevations in lab values Nursing Points General Normal value range Typically less than 0.035 ng/mL or less Can vary among institutions Has to be greater than the 99th percentile Pathophysiology Troponin is released during myocardial cell damage Decreased perfusion causes myocardial cell damage Causes of myocardial cell damage Myocardial infarction Demand ischemia Cardiogenic ACS Noncardiogenic Sepsis Renal failure Extreme exercise

Measuring cardiac injury marker(Troponin) tied to hospital mortality and long term symptoms! (My breakdown of the study for non medical people to understand.) A summary of an excellent prospective study from Harvard's Brigham and Women's Hospital. --- Support this podcast: https://anchor.fm/steven-donchey/support