The Incubator

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A weekly discussion about new evidence in neonatal care and the fascinating individuals who make this progress possible.Hosted by Dr. Ben Courchia and Dr. Daphna Yasova Barbeau.

Ben Courchia & Daphna Yasova Barbeau

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    • Jan 18, 2026 LATEST EPISODE
    • daily NEW EPISODES
    • 33m AVG DURATION
    • 837 EPISODES

    Ivy Insights

    The Incubator podcast is an incredibly valuable resource for neonatologists and other neonatal healthcare providers. With its mix of research review, interviews, and stories, this podcast offers a comprehensive and engaging look into the world of neonatology. Drs. Courchia and Barbeau do an excellent job of presenting new research and providing their insightful opinions on the papers they discuss. The journal clubs are particularly great, as they allow listeners to stay up-to-date with the latest developments in the field. Additionally, the interviews with various experts in neonatology are always interesting and informative, offering a unique perspective on important topics. Overall, The Incubator brings the neonatology community together in a dynamic way, making it an indispensable resource for anyone in this field.

    One of the best aspects of The Incubator podcast is its ability to provide a quick review of relevant information on the latest in neonatology. It saves listeners from having to search for or read numerous journals by condensing important details into a manageable format that can be easily consumed during commutes or while doing other activities. The hosts strike a perfect balance between providing enough information to understand the research and keeping episodes short enough to be convenient for busy professionals.

    However, one possible improvement for The Incubator podcast would be more frequent episode releases. While the content provided is excellent, waiting two weeks for each new episode can sometimes leave listeners wanting more. Increased frequency would allow for even more coverage of research papers and interviews with experts.

    In conclusion, The Incubator podcast is an amazing resource that fills a gap in the neonatology community. It provides crucial updates on research findings while also offering entertaining stories and interviews that keep listeners engaged. Drs. Courchia and Barbeau do an outstanding job of delivering informative content that is easy to consume amidst busy schedules. Overall, The Incubator is a must-listen podcast for anyone interested in staying informed about developments in neonatology.



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    Latest episodes from The Incubator

    #394 - The Pxxs: Pampers Creates the World's Smallest Diaper for 22-Week Preemies

    Play Episode Listen Later Jan 18, 2026 25:06


    Send us a textWhat if the smallest patients finally had a diaper designed just for them? For years, NICUs have struggled to find appropriately sized diapers for extremely premature infants, often resorting to makeshift solutions that compromised skin integrity and care quality. That changes now. In this breaking news episode, Ben sits down with Harry McCusker, Director of Research and Development for North America Pampers Diapers, to discuss the groundbreaking launch of the Pxxs diaper—the world's smallest commercially available diaper, specifically engineered for micropreemies born as early as 21-23 weeks gestation. Weighing less than a nickel and designed with input from NICU professionals worldwide, the Pxxs addresses critical challenges in skin protection, fluid management, and developmental care for our most vulnerable patients. Join us as we explore how this innovation represents more than just a smaller diaper—it's Pampers' commitment that every preemie deserves products designed with their unique needs in mind.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #393 -

    Play Episode Listen Later Jan 17, 2026 90:24


    Send us a textCould a simple blood test help identify chronic pulmonary hypertension when echo access is limited? This week on The Incubator Podcast, Ben and Daphna explore this question and others relevant to daily NICU practice. A Toronto study examines NT-proBNP as a practical diagnostic tool in extremely preterm infants.They also examine a puzzling finding from Italy and Belgium: despite near-universal antibiotic use in neonates with HIE undergoing cooling, actual culture-positive sepsis rates are surprisingly low. What does this mean for our approach to empiric antibiotics?Ben presents Norwegian data showing that serial physical exams cut antibiotic exposure in half for term and late preterm infants—without compromising safety. Daphna follows with research connecting NICU capacity strain to patient outcomes, underscoring why adequate staffing isn't just about comfort, but about survival.The episode concludes with Ben, Daphna, and Eli discussing the recent CDC changes to Hepatitis B birth dose recommendations. With federal guidance now diverging from AAP recommendations, how do we navigate conversations with families? They explore transmission risks parents may overlook and share approaches to shared decision-making when expert opinions conflict. A full week of neonatal medicine research and real-world clinical challenges, all in one episodeSupport the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #393 - [Neo News] -

    Play Episode Listen Later Jan 16, 2026 22:30


    Send us a textThis week on Neo News, we tackle the recent and controversial divergence between CDC and AAP guidelines regarding the birth dose of the Hepatitis B vaccine. With the CDC now recommending a deferred schedule for infants of Hepatitis B-negative mothers, we explore the clinical implications, the risks of vertical transmission, and the challenge of navigating discordant public health advice. We discuss how to handle shared decision-making in an era of waning vaccine confidence and why the "birth dose" remains a critical safety net in a community setting. Join us as we break down the data behind the headlines.----American Academy of Pediatrics. (2025, December 15). AAP: CDC decision on universal birth dose of hepatitis B vaccine irresponsible and purposely misleading. AAP News. https://publications.aap.org/aapnews/news/33980/AAP-CDC-decision-on-universal-birth-dose-of?searchresult=1?autologincheck=redirectedSupport the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #393 - [Journal Club] -

    Play Episode Listen Later Jan 15, 2026 24:57


    Send us a textIn this episode of Journal Club, Ben and Daphna review a retrospective cohort study from the Journal of Perinatology examining the association between NICU capacity strain and neonatal outcomes. We discuss how high census and acuity on admission day correlate with increased mortality and morbidity when adjusted for hospital and patient factors. Join us as we explore why being "slammed with admissions" is more than just a badge of honor—it's a critical safety metric for our patients.----The association of NICU capacity strain with neonatal mortality and morbidity. Salazar EG, Passarella M, Formanowski B, Rogowski J, Edwards EM, Halpern SD, Phibbs C, Lorch SA.J Perinatol. 2025 Dec;45(12):1801-1808. doi: 10.1038/s41372-025-02449-0. Epub 2025 Oct 20.PMID: 41116036 Free PMC article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #393 - [Journal Club] -

    Play Episode Listen Later Jan 14, 2026 18:25


    Send us a textIn this episode of The Incubator Podcast, Ben and Daphna review a pivotal population-based study from Norway examining a new approach to Early-Onset Sepsis (EOS). The hosts discuss whether serial physical examinations can safely replace routine antibiotic prophylaxis in at-risk term and late-preterm infants. With antibiotic exposure often far exceeding sepsis incidence, this study offers compelling data for a "less is more" strategy. Tune in as Ben and Daphna explore the safety, efficacy, and bedside implications of substituting automatic treatment with structured clinical monitoring—and what this means for reducing unnecessary interventions in the NICU.----Serial physical examination to reduce unnecessary antibiotic exposure in newborn infants: a population-based study. Vatne A, Eriksen BHH, Bergqvist F, Fagerli I, Guthe HJT, Iversen KV, Ud Din FS, van der Weijde J, Kvaløy JT, Rettedal S.Arch Dis Child Fetal Neonatal Ed. 2025 Nov 19:fetalneonatal-2025-329639. doi: 10.1136/archdischild-2025-329639. Online ahead of print.PMID: 41260908Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #393 - [Journal Club] -

    Play Episode Listen Later Jan 13, 2026 22:06


    Send us a textIn this episode of Journal Club, Ben and Daphna dive into a multicenter retrospective study from the European Journal of Pediatrics questioning the necessity of universal empiric antibiotics in neonates undergoing therapeutic hypothermia for HIE. Comparing Italian and Belgian cohorts, the team discusses the reality of a 111 Number Needed to Treat (NNT) for a single case of culture-proven sepsis. From the diagnostic challenges of overlapping clinical markers to the fascinating "asymptote" of postnatal leukocyte trends, we explore whether it's time to shift from routine to selective antibiotic use in our most complex patients.----Antibiotic use in neonates with hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia: time to rethink universal empirical treatment. De Rose DU, Piersigilli F, Auriti C, Campi F, Cortazzo V, Samaey A, Carkeek K, Martini L, Maddaloni C, Santisi A, Ronci S, Iacona G, Bersani I, Savarese I, Danhaive O, Cilio MR, Bernaschi P, Dotta A, Ronchetti MP.Eur J Pediatr. 2025 Nov 22;184(12):781. doi: 10.1007/s00431-025-06652-1.PMID: 41275063Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #393 - [Journal Club] -

    Play Episode Listen Later Jan 12, 2026 22:08


    Send us a textIn this Journal Club episode of the Incubator Podcast, Ben Courchia and Daphna Yasova-Barbeau review a study from the Journal of Perinatology evaluating NT-proBNP as a diagnostic tool for chronic pulmonary hypertension in extremely preterm infants. The discussion walks through the clinical burden of pulmonary hypertension in babies with bronchopulmonary dysplasia, the limitations of echocardiography, and the appeal of accessible biomarkers. Using data from a SickKids Toronto cohort, the hosts unpack sensitivity, specificity, cutoff values, and real-world applicability, while exploring how NT-proBNP could support screening, risk stratification, and bedside decision-making in everyday NICU practice.----Can N-terminal pro-brain natriuretic peptide accurately diagnose chronic pulmonary hypertension among extremely low gestational age neonates: A Retrospective Cohort Study. Garcia-Gozalo M, Jain A, Weisz DE, Jasani B.J Perinatol. 2025 Nov 13. doi: 10.1038/s41372-025-02462-3. Online ahead of print.PMID: 41233504Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #392 -

    Play Episode Listen Later Jan 10, 2026 90:48


    Send us a textThis week on The Incubator Podcast, Ben and Daphna review several recent studies in neonatal care. They start with a JAMA trial comparing expectant versus active PDA management in preterm infants, noting a survival signal favoring expectant care and discussing how this fits within current practice. They then review outcomes of 21-week gestation infants from the University of Iowa, focusing on resuscitation strategies and survival at the limits of viability.The conversation continues with the ICAF trial, examining whether extending caffeine therapy through 41 weeks postmenstrual age meaningfully reduces intermittent hypoxia and for which infants this may matter. A large national cohort study on antenatal corticosteroids between 21 and 24 weeks gestation is also discussed, highlighting practice variation and implications for counseling.The episode closes with a Neo News segment on legal liability in the NICU following a recent $32 million NEC settlement. Ben, Daphna, and Eli consider informed consent around nutritional care and how evolving legal pressures may influence communication and clinical decision making.This compilation brings together research and policy discussions from the week in a single long-form episode.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #392 - [Neo News] -

    Play Episode Listen Later Jan 9, 2026 24:46


    Send us a textIn this episode of Neo News, Ben, Daphna, and Eli tackle the complex and emotionally charged landscape of legal liability in the NICU. Following a recent $32 million settlement involving necrotizing enterocolitis (NEC) and cow's milk-based formula, the team debates the future of informed consent for routine nutritional care. They explore how legal precedents may force neonatologists to replace bedside counseling with transactional forms, potentially eroding trust and complicating evidence-based practice. Join us as we discuss how to balance transparency, parental autonomy, and the reality of risk in the pursuit of better outcomes for our tiniest patients.----WTNH News 8. (2025, December 15). Parents, attorneys emphasizing importance of informed consent to NICUs following baby's death at Yale New Haven Hospital. WTNH. https://www.wtnh.com/news/connecticut/new-haven/parents-attorneys-emphasizing-importance-of-informed-consent-to-nicus-following-babys-death-at-yale-new-haven-hospital/Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #392 - [Journal Club Shorts] -

    Play Episode Listen Later Jan 8, 2026 17:02


    Send us a textIn this Journal Club episode, Ben and Daphna review a large national cohort study examining the association between antenatal corticosteroid exposure and survival in extremely preterm infants born between 21 and 24 weeks' gestation. They discuss biologic plausibility, practice variation, and the challenges of interpreting retrospective data, while focusing on how these findings may inform counseling and shared decision-making at the margins of viability.----The Effects of Antenatal Corticosteroids on Extremely Premature Neonates Born between 21 and 24 Weeks. Yao R, Tritch N, Vedhanayagam K, Ali N, Reimche-Vu H, Gedestad I, Karageuzian S, Contag S.Am J Perinatol. 2025 Nov 6. doi: 10.1055/a-2722-8107. Online ahead of print. PMID: 41086871Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #392 - [Journal Club Shorts] -

    Play Episode Listen Later Jan 7, 2026 14:57


    Send us a textBen and Daphna review the ICAF randomized clinical trial evaluating extended caffeine therapy in preterm infants and its impact on intermittent hypoxia through 41 weeks postmenstrual age. They discuss the study design, oximetry outcomes across multiple saturation thresholds, inflammatory biomarkers including TNF-α, and clinically relevant safety signals such as oxygen restart rates, length of stay, and weight gain. The conversation focuses on what intermittent hypoxia may mean for ongoing risk, and whether a targeted subgroup of infants might benefit from extending caffeine beyond traditional stopping points.----Intermittent hypoxia and caffeine in infants born preterm: the ICAF Randomized Clinical Trial. Eichenwald E, Corwin M, McEntire B, Knoblach S, Limperopoulos C, Kapse K, Kerr S, Heeren TC, Ikponmwonba C, Hunt CE; ICAF Study Group.Arch Dis Child Fetal Neonatal Ed. 2025 Nov 24:fetalneonatal-2025-329230. doi: 10.1136/archdischild-2025-329230. Online ahead of print.PMID: 41285561Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #392 - [Journal Club Shorts] -

    Play Episode Listen Later Jan 6, 2026 28:22


    Send us a textIn this Journal Club episode, Ben and Daphna review a salient study from JAMA Network Open examining outcomes of infants born at 21 weeks' gestation at the University of Iowa. They walk through resuscitation practices, early physiologic challenges, survival trends, and short-term developmental outcomes, while placing the data in the broader context of shifting limits of viability. The discussion highlights both cautious optimism and the many unanswered questions that remain as neonatology continues to push the boundaries of what is possible.----Outcomes of Infants Born at 21 Weeks' Gestational Age. Hyland RM, Mat HD, Boly TJ, Thomas BJ, Stanford AH, Harmon HM, Bermick JR, Davila RC, Colaizy TT, Dagle JM, Klein JM, Greiner AL, Bell EF, McNamara PJ; University of Iowa Neonatology Program.JAMA Netw Open. 2025 Dec 1;8(12):e2548211. doi:10.1001/jamanetworkopen.2025.48211.PMID: 41385227 Free PMC article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #392 - [Journal Club Shorts] -

    Play Episode Listen Later Jan 5, 2026 21:52


    Send us a textIn this Journal Club episode, Ben and Daphna review a major randomized clinical trial published in JAMA comparing expectant management with active pharmacologic treatment of patent ductus arteriosus in preterm infants. They walk through the trial design, inclusion criteria, and outcomes, highlighting the unexpected survival difference favoring expectant management despite similar rates of bronchopulmonary dysplasia. The discussion explores the implications for bedside decision-making, the limitations of PDA-focused strategies, and the need for a more physiologic, patient-centered approach to ductal management in extremely preterm infants.----Expectant Management vs Medication for Patent Ductus Arteriosus in Preterm Infants: The PDA Randomized Clinical Trial. Laughon MM, Thomas SM, Watterberg KL, Kennedy KA, Keszler M, Ambalavanan N, Davis AS, Slaughter JL, Guillet R, Colaizy TT, Cotten CM, Dhawan MA, Bose CL, Talbert J, Smucny S, Benitz WE, Rysavy MA, Ohls RK, Baserga MC, DeMauro SB, Jaleel M, Jackson WM, Carlo WA, Puopolo KM, Hibbs AM, Katheria A, Sánchez PJ, D'Angio CT, Patel RM, Johnson BA, Chock VY, Bhatt AJ, Merhar SL, Moore R, Laptook AR, Ghavam S, Fuller J, Vyas-Read S, Kicklighter SD, Steinbrekera B, Anderson K, Reynolds AM, Wyckoff MH, Montoya C, Das A, Do B, Chang S, Higgins RD, Walsh MC; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.JAMA. 2025 Dec 9:e2523330. doi: 10.1001/jama.2025.23330. Online ahead of print.PMID: 41364689Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #391 -

    Play Episode Listen Later Dec 31, 2025 85:24


    Send us a textIn this episode of Beyond the Beeps, Leah MG Jayanetti discusses the unique challenges faced by families in the NICU during the holiday season. Joined by Alena Costume, a two-time NICU mother, they explore the emotional rollercoaster of having a baby in the NICU, the importance of community support, and strategies for coping with stress. Alena shares her personal experiences, highlighting the significance of parental presence and the impact of healthcare staff on the NICU journey. The conversation emphasizes resilience, hope, and the need for better support systems for NICU families. In this conversation, Leah MG Jayanetti and Alena discuss the profound experiences of families in the NICU, emphasizing the importance of nourishment, community support, and the unexpected connections that can arise during challenging times. They share personal stories about creating the Touching Tiny Hands organization, the emotional toll of having a child in the NICU, and the significance of hope and belonging in the journey of parenthood, especially during the COVID-19 pandemic.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #390 - End-of-Year Wrap-Up: What's Changing for The Incubator in 2026

    Play Episode Listen Later Dec 28, 2025 31:10


    Send us a textAs 2025 comes to a close, Ben and Daphna reflect on a year of growth, community, and evolution for The Incubator Podcast. In this end-of-year wrap-up, they preview major changes coming in 2026, including new standalone podcast feeds, expanded journal club content, CME opportunities, and exciting partnerships with organizations like the Vermont Oxford Network and PAS. They also share what's ahead for the Delphi Conference and offer a candid look at their personal and professional goals for the year ahead. Thank you for being part of this extraordinary neonatal community. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #389 - Discussion on the Business of Medicine with Dr. Giep

    Play Episode Listen Later Dec 25, 2025 33:54


    Send us a textTransitioning from fellowship to your first attending job? You're probably not prepared for the business side of medicine—and that's exactly the problem Dr. Tung Giep addresses in this episode. Dr. Giep, a neonatologist with over 30 years of experience, shares hard-earned lessons from building and selling a private practice in Houston, navigating toxic work environments, and eventually finding his place in telemedicine. His new book, The Business of Medicine: The Definitive Guide to Help New Physicians Start Their Career on the Right Path and Avoid Costly Mistakes, tackles what medical training ignores: contract negotiation, non-competes, choosing the right CPA and attorney, and understanding your self-worth.Ben and Dr. Giep discuss why new physicians get blindsided by job offers, how to vet a practice properly, and the reality of community neonatology versus academic medicine. They also explore the growing role of AI in healthcare and what it means for the next generation of physicians. Whether you're finishing fellowship or reconsidering your current position, this conversation offers practical guidance on taking control of your career—and avoiding costly mistakes along the way. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #388 -

    Play Episode Listen Later Dec 21, 2025 87:03


    Send us a textIn this Journal Club episode, Ben and Daphna review five recent studies with practical implications for neonatal care. The FEED1 trial examines whether starting full milk feeds from day one is safe in 30-32 week preterm infants, finding no difference in length of stay compared to gradual feeding but fewer central line days. A brief communication from UAB explores high-volume feeding strategies (≥170 ml/kg/day) and their impact on body composition in very preterm infants.The hosts discuss a mannequin study from Italy measuring forces applied during intubation with different laryngoscope types and bed heights, revealing that video laryngoscopy at navel height applies the lowest forces—contrary to most clinicians' perceptions.A large Japanese cohort study highlights the association between maternal psychological distress and neurodevelopmental delays, with postpartum distress showing stronger effects than prenatal stress. Finally, analysis of Neonatal Research Network data identifies predictors of early cord clamping in extremely preterm infants, with lack of magnesium sulfate, cesarean delivery, and antepartum hemorrhage being key factors.The episode wraps with reminders about upcoming conferences, including the Delphi Conference in Fort Lauderdale in January 2026.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #388 - [Journal Club Shorts] -

    Play Episode Listen Later Dec 21, 2025 14:03


    Send us a textAntenatal Prediction of Early Cord Clamping among Infants Born Extremely Preterm.Katheria A, Dorner RA, Grobman W, Rysavy MA, Koo J, Wyckoff MH, Sandoval G, DeMauro SB, Das A, Lee HC, Cotten M, Calvo L, Saha S; Eunice Kennedy Schriver National Institute of Child Health and Human Development Neonatal Research Network.J Pediatr. 2025 Oct 31:114878. doi: 10.1016/j.jpeds.2025.114878. Online ahead of print.PMID: 41177398Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #388 - [Journal Club Shorts] -

    Play Episode Listen Later Dec 21, 2025 13:19


    Send us a textMaternal Psychological Distress Before and After Childbirth and Neurodevelopmental Delay in Toddlers.Matsumura K, Tanaka T, Kuroda M, Tsuchida A, Hatakeyama T, Kasamatsu H, Inadera H; Japan Environment and Children's Study Group.JAMA Netw Open. 2025 Oct 1;8(10):e2540907. doi: 10.1001/jamanetworkopen.2025.40907.PMID: 41171271 Free PMC article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #388 - [Journal Club Shorts] -

    Play Episode Listen Later Dec 21, 2025 21:32


    Send us a textTreatment of Hypotension of Prematurity: a randomised trial.Alderliesten T, Arasteh E, van Alphen A, Groenendaal F, Dudink J, Benders MJ, van Bel F, Lemmers P. Arch Dis Child Fetal Neonatal Ed. 2025 Dec 15;111(1):F60-F66. doi: 10.1136/archdischild-2024-328253.PMID: 40413017 Clinical Trial.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #388 - [Journal Club Shorts] -

    Play Episode Listen Later Dec 21, 2025 13:42


    Send us a textApplied forces during neonatal intubation with direct and video laryngoscopy at different bed elevations: a randomized crossover manikin study.Cavallin F, Pasquali G, Maglio S, Villani PE, Menciassi A, Tognarelli S, Trevisanuto D.Eur J Pediatr. 2025 Nov 5;184(12):732. doi: 10.1007/s00431-025-06524-8.PMID: 41191125 Free PMC article. Clinical Trial.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #388 - [Journal Club Shorts] -

    Play Episode Listen Later Dec 21, 2025 8:19


    Send us a textEarly body composition outcomes of infants born very preterm and receiving high volume, human milk feedings (≥170 ml/kg/day) before postnatal day 14.Gunawan E, Molleti M, Salas AA.J Perinatol. 2025 Oct 31. doi: 10.1038/s41372-025-02469-w. Online ahead of print.PMID: 41174086 No abstract available.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #388 - [Journal Club Shorts] -

    Play Episode Listen Later Dec 21, 2025 14:37


    Send us a textFull exclusively enteral fluids from day 1 versus gradual feeding in preterm infants (FEED1): a open-label, parallel-group, multicentre, randomised, superiority trial.Ojha S, Mitchell EJ, Johnson MJ, Gale C, McGuire W, Oddie S, Hall SS, Meakin G, Anderson J, Partlet C, Su Y, Johnson S, Walker KF, Ogollah R, Mistry H, Naghdi S, Montgomery A, Dorling J; FEED1 collaborative.Lancet Child Adolesc Health. 2025 Dec;9(12):827-836. doi: 10.1016/S2352-4642(25)00271-8. Epub 2025 Oct 17.PMID: 41115446 Free article. Clinical Trial.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #387 -

    Play Episode Listen Later Dec 17, 2025 50:49


    Send us a textIn this episode of the Incubator, Betsy Crouch and David McCulley interview Dr. Wendy Chung, a leader in clinical genetics and child health research. They discuss her journey into genomics, the challenges faced in her career as a physician scientist, the importance of early mentorship, and her research interests, particularly in congenital diaphragmatic hernia (CDH). Dr. Chung shares insights on the complexities of genetic disorders and the need for innovative approaches in treatment and diagnosis. She discusses her experiences with newborn screening and the evolution of genetic screening for rare diseases, emphasizing the importance of advocacy for children's health research. The conversation highlights the impact of patient stories in research and concludes with personal insights into family activities and the importance of maintaining a balance between work and personal life.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 11, 2025 14:29


    Send us a textThree third-year fellows present diverse research at Hot Topics. Dr. Tanima from Boston Children's demonstrates lung ultrasound's potential to predict respiratory support duration in 30+ week infants, with first six-hour exams showing strongest correlation—suggesting possible replacement for admission chest x-rays. Dr. Juhi from University of Illinois in Chicago applies large language models to extract IVH prognostic variables from AI literature, identifying critical gaps including absence of resolution prediction studies. Dr. Hailey conducts qualitative research on physician experiences with NICU mortality/morbidity, identifying three impactful loss categories: outcome-expectation mismatches, meaningful relationships, and weight of responsibilities. Their work exemplifies emerging neonatologist interests in point-of-care ultrasound, artificial intelligence applications, and clinician wellbeing. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 10, 2025 22:14


    Send us a textDr. Jeffrey Gould and Dr. David Stevenson recount founding California Perinatal Quality Care Collaborative (CPQCC) in the mid-1990s, transforming California's fragmented perinatal care system. Initial success required organizational development expertise—not just databases—to transform stakeholders into partners by identifying mutual value. They created California Association of Neonatology, secured Packard Foundation support, and unified competing academic centers and private practitioners. CPQCC's disciplined approach—pods meeting biweekly, shared data, non-hierarchical teams—contributed to California achieving the nation's lowest maternal mortality while national rates climb. Gould emphasizes quality improvement as structural intervention building relationships and improving working conditions. For aspiring leaders, they advise: identify what teams value, use data to reveal challenges, build consensus around shared goals. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 10, 2025 11:22


    Send us a textDr. Elizabeth Foglia, University of Pennsylvania/Children's Hospital of Philadelphia and scientific PI for AAP's DRIVE (Delivery Room Intervention and Evaluation) Network, discusses building a 3,000-hospital US collaboration to understand real-world delivery room practices. Despite robust evidence supporting supraglottic airways for PPV in infants 34+ weeks, surveys show minimal provider use—representing a significant evidence-to-practice gap. The SUGAR trial compares implementation strategies to increase adoption using hybrid effectiveness-implementation design. DRIVE currently includes 50 hospitals with diverse delivery room configurations, providing infrastructure for pragmatic trials, quality improvement, and benchmarking. First network-wide meeting launches multi-center QI project in February. Sites can join via AAP DRIVE Network website. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 9, 2025 15:50


    Send us a text In this episode of The Incubator Podcast, recorded live at Hot Topics in Neonatology in Washington, DC, we sit down with Dr. Daniele De Luca, Chief of Pediatric and Neonatal Critical Care at AP-HP Paris-Saclay University and leader of one of Europe's largest NICUs. Dr. De Luca discusses the groundbreaking Lancet Child & Adolescent Health Commission on the Future of Neonatology, a three-year initiative involving over 100 global key opinion leaders addressing the critical innovation gap in our specialty. He explores why neonatal medicine has experienced a slowdown in therapeutic advances since the 1990s, despite treating patients who will become citizens for decades ahead. The conversation covers the multifactorial barriers to innovation—from regulatory challenges to funding constraints—and the Commission's comprehensive recommendations for industry, regulators, academic centers, and patient representatives. Dr. De Luca emphasizes the urgent need to avoid treating babies in 20 years the same way we did 20 years ago, highlighting specific examples like the decades-long journey from drug development to registration and the paradox of FDA-approved equipment. He calls for a united approach to elevate neonatology's profile, establish formal specialty recognition, and accelerate the translation of research into bedside care.  Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 9, 2025 15:33


    Send us a textDr. Michael Narvey, neonatologist and Vice President of Canadian Pediatric Society, challenges the validity of pre-discharge car seat testing. After leading Canadian work resulting in nationwide abandonment of the test in 2016, he argues the test doesn't represent real-world conditions (potholes, movement) and lacks evidence demonstrating it saves lives from apnea or desaturations. Based on 50 years of autopsy data, rare car seat-related deaths result from unsupervised asphyxiation when infants slide down onto straps—not from events in moving vehicles. Narvey distinguishes between eliminating the test versus maintaining essential car seat safety education, emphasizing proper positioning and avoiding unsupervised use outside vehicles. Some US centers are reconsidering this practice. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 9, 2025 10:14


    Send us a textNicole and Maureen from Lactalogics present innovative donor human milk processing using gentle ultra-high temperature pasteurization—exposing milk to heat for only 10 seconds versus 30-40 minutes with traditional methods. Their tube-in-tube system (milk and steam traveling opposite directions) maintains safety by eliminating pathogens while better preserving inherent nutrients. Products launching April 2026 include shelf-stable options for term infants (20 cal, 1.1g protein/100mL) and preterm infants (20 cal, 1.6g protein/100mL), plus a human milk fortifier reaching 24 calories. Donor moms require rigorous screening and 500+ ounce surplus. The shelf-stable format supports both in-hospital use and post-discharge bridging when mothers face milk supply challenges. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 9, 2025 20:35


    Send us a textDr. Matthew Laughon, Professor at University of North Carolina and NICHD Neonatal Research Network investigator, presents the landmark PDA Management Trial comparing expectant management versus active medical treatment (indomethacin, ibuprofen, or acetaminophen). The trial stopped early due to futility and safety concerns—mortality exceeded 10% in the treatment group versus 4% with expectant management, with more infection-related deaths among treated infants. Secondary outcomes (BPD, NEC, ROP) showed no differences. The study included infants with symptomatic PDAs but excluded those with severe cardiopulmonary compromise. Findings support expectant management for symptomatic PDAs through 21 days of life, aligning with recent guidelines recommending no routine treatment in the first two weeks. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 9, 2025 14:06


    Send us a textDr. Elaine Boyle, Professor of Neonatal Medicine at University of Leicester, presents the SURFON trial evaluating early surfactant versus expectant management in 34-38 week infants with respiratory distress. This pragmatic trial enrolled infants requiring 30-45% oxygen or non-invasive support. Primary outcomes showed no difference in hospital length of stay or progression to severe respiratory disease. Early surfactant reduced NICU duration and non-invasive support by less than one day each, with borderline pneumothorax increase requiring treatment of 80+ infants to prevent one case. Findings suggest watch-and-wait approaches remain safe and reasonable for this population, though this group requires continued research given their potential for severe illness. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 9, 2025 16:59


    Send us a textDr. Shalini Ojha, Professor of Neonatal Medicine at University of Nottingham, presents the Feed One trial examining full enteral feeding (60 mL/kg/day) from day one versus gradual advancement in 30-32 week infants. While the primary outcome of hospital length of stay showed no difference (median 32 days), full feeding significantly reduced parenteral nutrition use, IV cannulations, and associated interventions without increasing necrotizing enterocolitis risk (4 versus 6 cases). This pragmatic trial challenges the unfounded fear that early full feeding causes NEC—demonstrating that moderate preterm infants can safely receive complete enteral nutrition from birth, simplifying care particularly in resource-limited settings while avoiding complications from IV access and parenteral nutrition. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 9, 2025 9:59


    Send us a textDr. Pankaj Agrawal, Division Chief of Neonatology at University of Miami, discusses rapid genomic advances—from six-month diagnostic timelines in 2000 to same-day sequencing today. While current practice targets phenotype-based testing for unexplained conditions or dysmorphic features, Agrawal advocates moving toward universal NICU sequencing to identify previously unrecognized conditions. Key barriers include administrative buy-in, cost concerns, consent processes, and result disclosure challenges. Even negative results provide value—offering families reassurance and contributing to research databases. With only 5,000 of 20,000 genes linked to human disease, ongoing gene discovery work continues. Agrawal emphasizes the NICU as ideal for genomic implementation given high genetic disease prevalence and intervention opportunities. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 9, 2025 8:47


    Send us a textThree first-year fellows from University of Virginia—Jamie, Megan, and Brianne—share their Hot Topics conference experience. Despite being early in training, they engage deeply with cutting-edge research across diverse interests: POCUS and hemodynamics (Jamie), ENT non-surgical interventions (Brianne), and neurodevelopmental outcomes with Tiny Baby projects (Megan). They value learning from practice variation across institutions, particularly regarding fluid management and humidity protocols. Rather than finding evidence gaps discouraging, they're inspired by opportunities for future research. They plan to share conference insights through journal club upon returning to UVA. The fellows emphasize how accessible and collaborative neonatology speakers are, encouraging early-career engagement with research leaders. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 8, 2025 12:49


    Send us a textJulie Raskin, representing Congenital Hyperinsulinism International (CHI), advocates for universal newborn glucose screening following her son's brain injury from undiagnosed hyperinsulinism in 1996. Registry data reveals 28% of affected infants lack traditional risk factors (abnormal birth weight), and even high-risk babies are often discharged inappropriately. CHI's "Glucose is a Vital Sign" campaign promotes screening protocols currently under research, examining glucose plus ketone monitoring during initial days to identify affected infants without over-medicalizing healthy newborns. The organization maintains eight centers of excellence globally and provides international treatment guidelines at congenitalhi.org. Over 30 genes cause this diagnosable, treatable condition requiring immediate intervention to prevent preventable brain damage from prolonged hypoglycemia. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 8, 2025 13:50


    Send us a textDr. Ariel Salas, recent R01 recipient, discusses challenging traditional feeding volume targets in preterm infants. His multi-center trial compares 180-200 versus 140-160 mL/kg/day volumes, examining body composition changes rather than weight alone. Salas emphasizes targeting fat-free mass gains over simple weight gain, as this component associates with better long-term neurodevelopmental outcomes. Body composition analysis reveals compartmental changes invisible to daily weights—distinguishing extracellular versus intracellular water shifts. This outcome provides reasonable compromise between immediate intervention effects and long-term results. Salas advocates acknowledging practice variation as opportunity for equipoise and fair testing, challenging arbitrary standards that persist despite limited evidence supporting them. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 8, 2025 11:26


    Send us a textDr. Kavya Rao from University of Buffalo discusses quality improvement initiatives following completion of her master's in QI. Her team successfully implemented antibiotic stewardship by safely discontinuing antibiotics at 24 hours for early onset sepsis in clinically well infants with negative blood cultures, initially studying all gestational ages with plans for subset analysis. Additional projects include reducing PRBC and platelet transfusions using lower thresholds based on updated guidelines. Rao emphasizes finding QI topics through clinical passion and data-driven identification of performance gaps, using benchmarking with Vermont Oxford Network data. She co-mentors fellows in QI with Dr. Valerie Albertson and expresses enthusiasm for the Tiny Baby Collaborative, recognizing 22-weekers require distinct physiologic approaches. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 8, 2025 17:56


    Send us a textDr. Ravi Patel, Professor at Emory University and Chair of the Georgia Perinatal Quality Collaborative, examines the tension between quality improvement and evidence-based medicine. He argues NICUs should prioritize high-certainty interventions (antenatal steroids, delayed cord clamping) rather than standardizing practices based on low-certainty evidence. Using tools like GRADE to assess evidence certainty helps determine when standardization is appropriate versus when practice variation allows for shared decision-making. Patel advocates re-energizing evidence generation as improvement in common morbidities has stalled. Examples like Eat Sleep Console demonstrate the value of prospective evaluation when adopting new practices. When evidence is uncertain, integrating family values and preferences becomes essential for individualized care decisions. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 8, 2025 11:54


    Send us a textDr. Edgardo Szyld from Indiana University presents the PLANT study evaluating 20 minutes of prophylactic CPAP for late preterm infants (34-36+6 weeks) born via cesarean section. This population represents 70% of US preterm births and experiences five times higher respiratory distress rates with cesarean delivery. The pragmatic pilot enrolled 100 patients, demonstrating reduced NICU admissions without pneumothorax cases—addressing previous safety concerns from observational data. Szyld's team is planning PLANT 2, targeting 35-36 weekers across 11 international centers, which will compare outcomes with and without antenatal steroids. This pragmatic approach addresses a high-volume but understudied population significantly impacting NICU resources. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 8, 2025 14:11


    Send us a textDr. Clara Song, Chair of the AAP Section on Neonatal-Perinatal Medicine, discusses urgent workforce challenges facing neonatology. With average neonatologist age around 50-55 and stable fellowship applications despite growing positions, the field faces potential shortages. The section launched initiatives addressing fair compensation, including a new website comparing negotiated commercial payer rates across states and engaging state chapters for payer advocacy. Song highlights concerning trends where neonatologist productivity increased while compensation decreased as the field became female-dominated. She discusses the section's comprehensive staffing toolkit and proposes restructured training pathways—potentially shortened residency with targeted 2-5 year fellowships—to attract trainees while ensuring adequate clinical preparation for increasingly complex neonatal care. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    song coverage hot topics neonatology neonatal perinatal medicine
    #386 -

    Play Episode Listen Later Dec 8, 2025 11:55


    Send us a textDr. Louise Owen from Royal Women's Hospital Melbourne presents the AEROPLANE trial comparing 21% versus 30% oxygen for 32-35 week infants at birth. This understudied cohort represents 80% of preterm births globally. Using cluster randomization with waived consent, the trial captured real-world practice across centers. Infants receiving 30% oxygen required less delivery room intervention including assisted ventilation, intubation, and chest compressions. Three-quarters of infants needing initial support continued requiring respiratory support beyond delivery. Both groups ultimately received average oxygen in the 50s, suggesting moderate preterm infants may behave more like very preterm rather than term babies regarding oxygen needs. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 8, 2025 10:00


    Send us a textDr. Divya keerthy (New York Presbyterian Queens/Weill Cornell Medicine) and Dr. Katherine Nyman (UCSD/Rady Children's, San Diego) discuss their Hot Topics conference experience. Keerthy presents research on prenatal polycyclic aromatic hydrocarbon exposure measured via backpack monitors and silicone wristbands during the third trimester. Her longitudinal study tracked infant microbiome at three time points over six months, identifying two air pollutants affecting microbiome development. Nyman highlights interest in the Tiny Baby collaborative, particularly PDA management challenges in extremely premature infants. Both emphasize the value of Hot Topics' evidence-based sessions including "green and rotten apples" that stress-test current practices. They note the conference's focus on moderate preemies (32-34 weekers) who comprise 80% of NICU populations yet receive less research attention. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #386 -

    Play Episode Listen Later Dec 8, 2025 12:03


    Send us a textDr. Katherine P Callahan, neonatologist and bioethicist at Children's Hospital of Philadelphia, discusses the complexity of genetic testing in neonatal care. While the NICU serves as a launch point for genetic technologies due to high prevalence of genetic disease, genetic information is often ambiguous or uncertain rather than straightforwardly diagnostic. Variants of uncertain significance represent just one challenge—even clearly pathogenic findings may have unclear implications for individual patients, as demonstrated when parents carry the same mutation as their severely affected child. Callahan emphasizes that genetic information poses "informational hazards" requiring careful consideration of psychological and ethical impacts. She advocates for acknowledging complexity, rethinking outcomes beyond traditional measures, and embracing shared decision-making rather than standardized approaches to genomic counseling. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #385 - Dr. Andrew Beverstock - Exploring Neonatal Nutrition: The Role of Urinary Sodium

    Play Episode Listen Later Dec 3, 2025 33:31


    Send us a textIn this episode, Dr. Andrew Beverstock discusses his research on urinary sodium and its relationship with growth in preterm neonates. He shares insights into the importance of sodium for neonatal growth, the methodology of his study, and the unexpected results that challenge existing literature. The conversation also touches on his diverse medical training, mentorship experiences, and his involvement in medical education and point-of-care ultrasound (POCUS). Dr. Beverstock emphasizes the significance of careful population selection in research and outlines his future research directions. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #384 - Finding Your Voice After Prematurity: A Conversation with Mandy Daly

    Play Episode Listen Later Nov 30, 2025 52:32


    Send us a textIn this episode, Mandy Daly shares her profound journey as a NICU parent and her advocacy work through the Irish Neonatal Health Alliance (INHA). She discusses the emotional challenges faced by parents of preterm infants, the importance of family-centered care, and the need for systemic changes in neonatal healthcare. Mandy emphasizes the significance of building support networks, empowering families through education, and the impact of lived experiences in shaping healthcare policies. The conversation highlights the collaborative efforts required to improve outcomes for families navigating the complexities of neonatal care. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #383 -

    Play Episode Listen Later Nov 26, 2025 72:58


    Send us a textIn this episode, Leah Jayanetti speaks with Keira Sorrells, founder of the NICU Parent Network, about her personal journey through the NICU experience with her triplets and the advocacy work she has undertaken to support NICU families. They discuss the importance of family-centered care, the NICU Babies Bill of Rights, and the emotional challenges faced by parents in the NICU. Kira shares her insights on healing through storytelling and the need for self-care among NICU leaders, emphasizing that hope is an expression of love, regardless of the outcomes.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #382 –

    Play Episode Listen Later Nov 23, 2025 60:09


    Send us a textIn this episode of NeoNews, the team returns from a brief hiatus with a refreshed format and a packed review of neonatal stories dominating recent headlines. Eli, Ben, and Daphna open with updates on RSV prevention, highlighting new MMWR data showing significant gaps in nirsevimab and maternal vaccine uptake—despite strong evidence and renewed availability. They discuss how supply chain issues, insurance delays, and vaccine confusion continue to limit access, and they emphasize the unique role neonatologists can play in counseling families early and often. The hosts also review concerning national trends in congenital syphilis, noting that many affected infants had parents who received prenatal care but were never tested—an avoidable systems failure with major downstream costs. Additional segments cover the severity of last year's influenza season, the emergence of new RSV monoclonal antibodies, and the rising use of polygenic risk scoring in IVF. The team reflects on the ethical tension between innovation and eugenics concerns, and how neonatal providers can prepare for these conversations. Finally, the deep dive explores Sherri Fink's powerful reporting on trisomy 18, variability in care across institutions, and the growing emphasis on transparent, value-driven shared decision-making with families. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #381 - Dr. Sidney Zven's Research on Addressing Food Insecurity in Military Families

    Play Episode Listen Later Nov 21, 2025 37:23


    Send us a textIn this episode, Dr. Sidney Zven shares his unique journey from a civil engineering career to becoming a neonatology fellow at Walter Reed Military Medical Center. He discusses his experiences with food insecurity among military families, particularly focusing on WIC enrollment challenges and the impact of stigma and misinformation. Dr. Zven highlights his mentorship experience while working on a grant to address these issues and the importance of engaging stakeholders in community health initiatives. He also provides insights into his neonatology fellowship training and his aspirations for the future in military medicine. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #380 -

    Play Episode Listen Later Nov 20, 2025 59:58


    Send us a textIn this episode of At the Bench, Misty Good and David McCulley interview Dr. Bernard Thébaud, a neonatologist and leader in lung and pulmonary vascular developmental biology and regenerative medicine. The conversation explores Dr. Thebaud's journey into research, the importance of mentorship, and the challenges of translating research into clinical practice. They discuss the significance of recognizing opportunities, navigating critical feedback, and the promising mechanisms in regenerative medicine that could enhance lung repair in preterm infants. Dr. Thébaud discusses the innovative use of mesenchymal stromal cells in lung therapy for neonatal patients. He shares insights on the unexpected findings from his research, the potential of umbilical cord-derived cells, and the future of neonatal lung regenerative medicine. The conversation also touches on the importance of mentorship, resilience in research, and fostering a positive lab environment.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    #379 -

    Play Episode Listen Later Nov 19, 2025 21:47


    Send us a textIn the final episode of our Rethinking Phototherapy series, Ben speaks with Steve Falk, Chief Engineer of the Maternal Infant Care Strategic Business Unit at GE Healthcare. With more than three decades of engineering leadership, Steve has been instrumental in the development of landmark neonatal technologies, including the Giraffe Omnibed and Panda platforms.This conversation highlights the critical role of engineering in making phototherapy precise, reliable, and safe. Steve explains how advances in LED technology have transformed phototherapy devices, ensuring consistent irradiance and long product life. He describes how engineers translate clinical needs—wavelength, intensity, surface coverage, and distance—into product requirements, and how rigorous usability testing with clinicians shapes intuitive bedside tools. The discussion also explores innovation on the horizon, from refining intermittent phototherapy strategies to integrating technologies that simplify care and support earlier discharge.Listeners will gain a behind-the-scenes perspective on how engineering teams think about phototherapy as a true pharmacotherapy, and how collaboration between clinicians and industry can directly improve outcomes for newborns and families. This episode closes the series by reminding us that innovation in neonatal care happens not only in clinical practice, but also in the design labs where these essential tools are created.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

    Claim The Incubator

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