Podcasts about Pyridoxine

Moderator: BobbieJean Sweitzer, M.D. Participants: Daqing Ma, Ph.D. and Kate Leslie, M.B.B.S., M.D. Articles Discussed: Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecologic Laparoscopic Surgery: A Double-blind Randomized Controlled Trial B6 or Be Sick? Pyridoxine to Prevent Postoperative Nausea and Vomiting Transcript

Today we're continuing our series on nutrients and their effects on period pain and endo pain, and this episode is about B6. Now, we've already talked a lot about the powers of B6 for hormonal health, but what about its effects on pain? B6 can support us with pain reduction in a number of ways. Read more. Show notes B6 pain relieving/anti-inflammatory properties https://pmc.ncbi.nlm.nih.gov/articles/PMC4519769/ https://pmc.ncbi.nlm.nih.gov/articles/PMC5902457/ https://www.fertstert.org/article/S0015-0282(08)01969-9/fulltext https://pubmed.ncbi.nlm.nih.gov/39421613/ https://obgyn.onlinelibrary.wiley.com/doi/abs/10.1002/ijgo.16096 https://pubmed.ncbi.nlm.nih.gov/8361989/ https://pubmed.ncbi.nlm.nih.gov/11401933/ https://www.sciencedirect.com/science/article/abs/pii/0090698074900549 https://www.researchgate.net/publication/328373051_Effect_of_Pyridoxine_on_Prostaglandin_Plasma_Level_for_Primary_Dysmenorrheal_Treatment https://www.mdpi.com/2227-9059/11/9/2578 Period pain and B6 https://pmc.ncbi.nlm.nih.gov/articles/PMC10178419/ https://www.researchgate.net/publication/328373051_Effect_of_Pyridoxine_on_Prostaglandin_Plasma_Level_for_Primary_Dysmenorrheal_Treatment Endo and low B6 https://pubmed.ncbi.nlm.nih.gov/39421613/ https://obgyn.onlinelibrary.wiley.com/doi/abs/10.1002/ijgo.16096 https://www.mdpi.com/2673-4184/4/4/34 https://pmc.ncbi.nlm.nih.gov/articles/PMC10227355/ B6 and period pain relief https://pmc.ncbi.nlm.nih.gov/articles/PMC27878/ https://pmc.ncbi.nlm.nih.gov/articles/PMC3208934/ https://www.researchgate.net/publication/328373051_Effect_of_Pyridoxine_on_Prostaglandin_Plasma_Level_for_Primary_Dysmenorrheal_Treatment https://www.researchgate.net/publication/289295997_Therapeutic_effect_of_vitamin_B6_on_gastro-intestinal_symptoms_of_primary_dysmenorrhea_in_young_women_in_Yazd_City_2006-2009 https://www.mdpi.com/2673-4184/4/4/34 https://pmc.ncbi.nlm.nih.gov/articles/PMC10227355/ B6 dosing safety https://www.nhs.uk/conditions/vitamins-and-minerals/vitamin-b/#:~:text=The amount of vitamin B6,mg a day for women https://pmc.ncbi.nlm.nih.gov/articles/PMC10343656/ https://www.lareb.nl/en/news/nerve-damage-due-to-the-use-of-nutritional-supplements-with-vitamin-b6/#:~:text=Excessive intake of vitamin B6,in hands and/or feet.&text=Products containing vitamin B6 are,, pharmacies, supermarkets and online. Need more help or want to learn how to work with me? Free resources: This podcast!  Endometriosis Net Column Endometriosis News Column Newsletter Instagram Ways to work with me: This EndoLife, It Starts with Breakfast digital cookbook Masterclasses in endo nutrition, surgery prep and recovery and pain relief Live and Thrive with Endo: The Foundations DIY course One to one coaching info and application This episode is sponsored by BeYou Cramp Relief Patches. Soothe period cramps the natural way with these 100% natural and discreet menthol and eucalyptus oil stick on patches. Click here to find out more and to shop: https://beyouonline.co.uk/pages/how-it-works Produced by Chris Robson

Marjorie Dixon and Annemiek van Wegberg join guest host Curtis Coughlin II to complete the treatment puzzle in pyridoxine dependent epilepsy and explain the role and practicalities of lysine restriction in PDE. Dietary management for pyridoxine-dependent epilepsy due to α-aminoadipic semialdehyde dehydrogenase deficiency, a follow-on from the international consortium guidelines Marjorie Dixon, et al https://doi.org/10.1002/jmd2.12418

ADHD is the most common neurodevelopmental disorder in children under 18. The prevalence of ADHD is rising dramatically, with 1 in 20 children being on behavior modifying medications such as Adderall and Ritalin. These are medications that act as central nervous system stimulants, and can cause nervousness, agitation, anxiety, insomnia, vomiting, mood swings, an increased heart rate, increased blood pressure and even psychosis in susceptible individuals. Most research indicates the increase in ADHD is directly linked to poor gut health, the food that children eat, how they sleep and even how they breath. Join us in this episode as we explore natural alternatives for ADHD including diet, lifestyle, and supplements, that can help your kids (and adults) focus better and beat hyperactivity. Citations 1. Checa-Ros A, Jeréz-Calero A, Molina-Carballo A, Campoy C, Muñoz-Hoyos A. Current Evidence on the Role of the Gut Microbiome in ADHD Pathophysiology and Therapeutic Implications. Nutrients. 2021;13(1):249. Published 2021 Jan 16. doi:10.3390/nu13010249 2. Altun H, Şahin N, Belge Kurutaş E, Güngör O. Homocysteine, Pyridoxine, Folate and Vitamin B12 Levels in Children with Attention Deficit Hyperactivity Disorder. Psychiatr Danub. 2018;30(3):310-316. doi:10.24869/psyd.2018.310 3. Patrick RP, Ames BN. Vitamin D and the omega-3 fatty acids control serotonin synthesis and action, part 2: relevance for ADHD, bipolar disorder, schizophrenia, and impulsive behavior. FASEB J. 2015;29(6):2207-2222. doi:10.1096/fj.14-268342 4. Meg St-Esprit McKivigan. Nature Deficit Disorder is Really a Thing. June 23, 2020. The New York Times. https://www.nytimes.com/2020/06/23/parenting/nature-health-benefits-coronavirus-outdoors.html?smid=url-share --- Support this podcast: https://podcasters.spotify.com/pod/show/elanie-welch/support

On this episode, I discuss pyridoxine pharmacology, adverse effects, and important clinical uses. Pyridoxine is most well known for its potential to reduce the likelihood of isoniazid-induced neuropathy. Another common indication of pyridoxine is its use for nausea and vomiting associated with pregnancy. Pyridoxine plays an important role in the production of heme, so deficiency will increase the risk for anemia.

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Dr Spyros Batzios describes a patient diagnosed with hyperphosphatasia with mental retardation syndrome 3 (also known as Mabry Syndrome) and reports on novel findings of CSF abnormalities and response to treatment with pyridoxine and folinic acid. Hyperphosphatasia with mental retardation syndrome 3: Cerebrospinal fluid abnormalities and correction with pyridoxine and Folinic acid Martina Messina, et al https://doi.org/10.1002/jmd2.12347

Wondering what the newest pharmaceutical, nutritional, herbal and other treatments are for helping to heal migraines once and for all? We cover it today! Dr. Asare Christian is a board-certified physical medicine and rehabilitation physician (physiatrist) and the owner of Aether Medicine - an integrative pain management and rehabilitation clinic in Wayne, Pennsylvania that serves clients from around the globe. https://aethermedicine.com/ Dr. Kate Henry is the Director of Functional Medicine at Sanare Today, a practice that combines therapy, psychiatry, nutrition, natural medicine, coaching and more to help people thrive. https://sanaretoday.com/functional-medicine-program/ Dr. Christian and Dr. Kate discuss the latest advances in migraine treatment including new pharmaceuticals, devices, nutrients, herbs and supplements that help to prevent and reduce migraines in this free 30 minute talk. This presentation is a great resource for people who are looking to create a holistic healing plan that puts the power back in their hands when it comes to reducing and preventing migraines holistically. Topics covered in this talk The newest pharmaceutical advances in treating migraine New non-drug devices that help to reduce migraine Injectables that reduce migraine Herbal medicines that are effective for preventing and reducing migraines Minerals that reduce migraines Vitamins that help to reduce migraines How to make food-as-medicine a reality for you so that you can take back the power of your diet and nutrition in managing migraines Some of the papers mentioned in this talk Nutrients to Improve Mitochondrial Function to Reduce Brain Energy Deficit and Oxidative Stress in Migraine PMID 34959985 “The nutrients that can be considered to supplement the diet to prevent and/or ameliorate migraine are riboflavin, thiamine, magnesium ions, niacin, carnitine, coenzyme Q10, melatonin, lipoic acid, pyridoxine, folate, and cobalamin.” Zinc: Assessing the Effect of Zinc Supplementation on the Frequency of Migraine Attack, Duration, Severity, Lipid Profile and hs-CRP in Adult Women PMID: 33987139 CoQ10 Effectiveness of coenzyme Q10 in prophylactic treatment of migraine headache: an open-label, add-on, controlled trial PMID: 27670440 B vitamins. Section on Pyridoxine, Folate, and Cobalamin (PMID: 34959985) “Sadeghi et al. observed that pyridoxine intake (80 mg/day) in 66 patients with migraine with aura resulted in beneficiary effects on headache severity, HDR, and migraine attack duration, but not their frequency [161]. Melatonin: 4mg taken nightly over 6 months reduce attack frequency by roughly ⅔ and headache impact by roughly ⅓ PMID: 27027892 Herbal Medicine: Petasites hybridus root (butterbur) is an effective preventive treatment for migraine DOI: https://doi.org/10.1212/01.WNL.0000147290.68260.11 Each of us is here to help you and your loved ones! --- Send in a voice message: https://anchor.fm/drkatehenry/message

The Vitamins, Minerals, and Supplements series on SELF HEALTH is intended for educational purposes only.

In this episode, we review the high-yield topic of Vitamin B6 (Pyridoxine) from the Nutrition section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets

Vitamin B6 is essential for your overall health, but it is often overlooked. Learn how this nutrient can support your brain, heart and more! Take advantage of an exclusive podcast offer today by visiting www.invitehealth.com/podcast or by clicking here. For more information on the products or studies mentioned in this episode, click here. 

Peter Clayton, Emma Footitt and Curtis Coughlin join us to discuss the new consensus guidelines for PDE-ALDH7A1 disease. Professor Clayton explains the pathophysiology and history of the condition. Dr Footitt and Dr Clayton discuss the metabolic investigations of early onset seizures as well as the proposed management of pyridoxine-dependent epilepsy. Consensus guidelines for the diagnosis and management of pyridoxine‐dependent epilepsy due to α‐aminoadipic semialdehyde dehydrogenase deficiency Curtis R. Coughlin et al. https://doi.org/10.1002/jimd.12332

After a short hiatus, the boys are back with a brand new podcast. This time around we break down toxin and poison-related seizures, while sprinkling in some hilarious stories of seizure patients we have seen and treated. It took a little time to put this together because our microphone kept seizing. Don't wait another minute! Start listening now!

There are 18 different B Vitamins, and they have a major influence on your health. But last week, we only covered three! So the saga continues... In this episode, we talk about --Why Vitamins should not be taken for granted as they are the building blocks for getting well and having optimal performance. --How you need a daily supply of water soluble vitamins like Vitamin B and Vitamin C. --The reason that Vitamin B-4 (Adenine) isn't often covered in discussions of Vitamin B, but is often in need of supplementation. And the role Adenine plays in healing damage to the heart, improving the immune system, and boosting function of memory and the brain. --How Adenine supplementation helps with Fibromyalgia, cardiac arrhythmia, chronic constipation, diabetes, infections, and Armenia. And how Dr. Prather says Adenine is absolutely critical for almost every Parkinson's Disease patient, as well as patients with Alzheimer's Disease. --The importance of Vitamin B-5 (Pantothenic Acid) supplementation for the adrenal glands. And how Vitamin B-5 is known as the anti-stress, anti-anxiety, and anti-depression vitamin. --Why almost everyone with neuropathy in the feet needs Vitamin B-5 supplementation. And why The Prather Practice gets "really good results" in getting neuropathy under control. --The three populations most at risk for Vitamin B deficiencies: children, pregnant women, and the elderly. And the way Vitamin B-5 supplementation can help the elderly with coordination and balance issues to avoid falls. --The big difference Vitamin B-5 can make for acne and skin irritation issues. --How Vitamin B-6 (Pyridoxine) is helpful for almost everybody with carpal tunnel syndrome. Plus, how Vitamin B-6 helps with sciatica, eczema, psoriasis, dandruff, oily face, kidney stones, and PMS. --Why cracks of the lips and tongue indicate Vitamin B-6 deficiency. And why Vitamin B-6 is "extremely helpful" for learning disorders, dyslexia, and autism. www.TheVoiceOfHealthRadio.com  

Ask the Mentors Episode Topic: What are you finding is working best for your clients the bezwecken Progonb-l4x Phytob-l4x or the Pro-adapt and est-adapt?Client Case: Helping female client balance their blood sugar if they are Type 1 Diabetic. Client has tried Paleo, keto, vegan. Experiencess really low life threatening blood sugar drops, but they are medically induced.  Is there any correlation to IgA Immunodeficiency detected with blood work and Sec IgA levels on the GI Map?Would Secretory IgA on GI Map be low if a person was taking immunosuppressant drugs?Decreasing Sec IgA, what are some strategies outside of these topics to increase Sec IgA?Amazon A-P and Amazon A-F, how to take, with or without food?Client Case: Female client who is severely constipated, doing the GI Map but wants some relief ahead of time while she is on the Interphase plus. Suggestions beside magnesium citrateDoes P5P and B6 have similar dosing? Dosing: 100 mg/day of Pyridoxine hydrochloride or 25+ mg/day of P-5-P  

Last week, we began a two-part series on Vitamins and talked about Fat Soluble Vitamins. This week, we focus on Water Soluble Vitamins (like Vitamins B and C). In this episode, find out: --How water soluble vitamins are needed on a daily basis, while fat soluble vitamins are stored by the body. --Why Dr. Prather "guarantees" that everyone on a pharmaceutical needs additional nutritional supplementation. --That Vitamin B-1 (Thiamine) can help with Asperger's, Autism, Heart Disease, and digestion. And why those who drink too much will "automatically have a Thiamine deficiency", but Thiamine can actually help alcoholics to stop drinking. --How 28 million Americans have a Vitamin B-2 (Riboflavin) deficiency, which causes cracks around the corners of your mouth, inflamed tongue, eye redness, vision problems, skin problems, and nerve problems such as neuropathy. And why Riboflavin is "very, very important" for pregnant Moms, Diabetics, and migraine headache patients. --Why Vitamin B-3 (Niacin) is important for good cholesterol, memory, cognitive function, mood, and red blood cell formation. But Dr. Prather also says "you have to be careful with Niacin" and not take too much of it. --That "organ meats are better for you than regular meats", being lower in fat and more concentrated in vitamins and minerals. --That Vitamin B-5 (Pantothenic Acid) is considered the "anti-stress and anti-anxiety" vitamin that is good for depression, hair loss, and acne. And how Dr. Prather has used this supplement to get patients off of their anti-anxiety prescriptions. --Why Vitamin B-6 (Pyridoxine) is important for ankle swelling, learning disabilities, dandruff, PMS, and cracking of the lips and tongue. --How Folic Acid is "the most common vitamin deficiency", resulting in birth defects, depression, irritability, weight loss, and anorexia. Plus, how Vitamin B-12 must be balanced in conjunction with Folic Acid for both of them to work correctly in your body. --That bleeding of the gums is a sign of Vitamin C deficiency, while diarrhea is a sign that you are taking too much Vitamin C. And that Vitamin C can help with easy bruising and bed sores. www.TheVoiceOfHealthRadio.com

In this episode I discuss the must-know facts about vitamins B1-B7 (i.e. thiamine, riboflavin, niacin, pantothenic acid, pyridoxine, and biotin). Enjoy! The Med School Phys podcast discusses topics in human physiology. Our primary aim is to help medical students learn/review high yield material for their classes and board exams. Hopefully listeners find that this alternative audio-based learning format works for them. This podcast is intended to be educational and all the information shared herein is publicly available through the internet. Med School Phys is an independent project and currently shares no affiliation with other organizations, companies, or academic institutions.-You can email me questions or constructive feedback at medschoolphys@gmail.com -Check out my book, Read This Before Medical School: https://www.amazon.com/dp/B07YCXZM3X/ref=docs-os-doi_0 -Episode transcriptions can be found at: https://drive.google.com/drive/folders/12QQSFho-ThIIeZuulsblGSnnNL8oJ7ag?usp=sharingDISCLAIMER: All information, content, and materials published by the Med School Phys podcast are for informational purposes only and are NOT intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified healthcare provider. Please consult your healthcare provider regarding personal medical decisions.

In this episode I discuss the must-know facts about vitamins B1-B7 (i.e. thiamine, riboflavin, niacin, pantothenic acid, pyridoxine, and biotin). Enjoy! The Med School Phys podcast discusses topics in human physiology. Our primary aim is to help medical students learn/review high yield material for their classes and board exams. Hopefully listeners find that this alternative audio-based learning format works for them. This podcast is intended to be educational and all the information shared herein is publicly available through the internet. Med School Phys is an independent project and currently shares no affiliation with other organizations, companies, or academic institutions.You can email me questions or constructive feedback at medschoolphys@gmail.comYou can share a link to our episodes via Spreaker or encourage others to listen on their podcasting app of choice: https://www.spreaker.com/user/medschoolphysFind our Youtube channel at: https://www.youtube.com/channel/UCXEEgC1JZysYsKy9NRYisEQEpisode transcriptions can be found at: https://drive.google.com/drive/folders/12QQSFho-ThIIeZuulsblGSnnNL8oJ7ag?usp=sharingDISCLAIMER: All information, content, and materials published by the Med School Phys podcast are for informational purposes only and are NOT intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified healthcare provider. Please consult your healthcare provider regarding personal medical decisions.

Welcome to the Power Plant Podcast! Know your enemy! In this episode we'll talk about Stress and ways to combat it through herbal nutrition. We discuss the physical effects of stress as well as the warning signs. We will discuss different ways to regulate the nervous system and recommend some powerful herbs and extracts to combat fatigue. In this episode we will be taking calls from John in New York, who has a high stress job and can't seem to turnoff the mental chatter after work hours. We'll also hear from Sharon in Washington DC, who also has a very demanding job and is looking for a natural way to combat stress. Last we will hear from Lucy in Portland who lost her job, has two kids and is looking for something to help with focus as well as combat stress.    This show is sponsored by Dr. Vim's Herbal Nutrition. Dr. Vim's herbal formulas are designed for men and women to  mental focus, physical energy, stress reduction and a healthy libido. They use only filler free high potency botanical extracts. ensuring that every batch delivers a full dose of the most powerful phytonutrients on the planet.    Podcast 2: Stress: 3 types of stress responses: Social Engagement Mobilization Immobilization   1. Social engagement - our most evolved strategy for keeping ourselves feeling calm and safe. Since the vagus nerve connects the brain to sensory receptors in the ear, eye, face and heart, socially interacting with another person can calm you down and deescalate a “fight-or-flight” type response. When using social engagement you can think clearly, and body functions such as digestion, the immune system, blood pressure, and heartbeat continue to work normally. 2. Mobilization -commonly referred to as "fight-or-flight" response. When social engagement is no longer an appropriate response and we need to either defend ourselves or run away from danger, the body prepares for mobilization. It releases hormones and neurotransmitters to provide the energy you need to protect yourself. When this happens, body functions such as digestive function and immune function, stop working. Under normal conditions, when the danger has passed your nervous system calms the body, the heart rate and blood pressure normalize, and the body goes back into balance. 3. Immobilization - the least evolved response to stress and used by the body only when social engagement and mobilization have failed. You may find yourself traumatized or frozen in an angry, panic-stricken or otherwise dysfunctional state. In extreme, life-threatening situations, you may even lose consciousness or find yourself enabled to survive high levels of physical pain. However, until you’re able to deescalate to a mobilization response, your nervous system may be unable to return to its pre-stress state of balance.   Inappropriate Stress Response!! While it’s not always possible to respond to stress using social engagement, many of us have become conditioned to responding to every minor stressor by immediately resorting to fight or flight. Since this response interrupts other body functions and clouds judgment and feeling, over time it can cause stress overload and have a detrimental effect on both your physical and mental health. Effects of stress overload The body’s autonomic nervous system often does a poor job of distinguishing between daily stressors and life-threatening events. For example: you have a mild, low level stress situation in life and have a stress response like you’re facing a life-or-death situation. When you repeatedly experience the fight or flight stress response in your daily life, it can raise blood pressure, suppress the immune system, increase the risk of heart attack and stroke, speed up the aging process and leave you vulnerable to a host of mental and emotional problems.   Health problems which are caused or exacerbated by stress include: Pain of any kind Heart disease Digestive problems Sleep problems Depression Weight problems Auto immune diseases Skin conditions, such as eczema   Common warning signs of chronic stress: Memory Problems Inability to concentrate Poor judgements Moodiness Sense of loneliness and isolation Depression or general unhappiness Aches and pains Digestive problems Nausea Chest pain or rapid heartbeat Loss of libido Weakened immune function Eating more or less Sleeping problems Substance abuse   Power Plants that promote a healthy stress response:   Energizing herbs for stress management 1. Ashwagandha - The flagship herb of Ayurveda supports healthy adrenal function, energy, and mental focus. Ashwagandha (KSM-66) has been clinically researched and is backed by several randomized, double-blind, placebo controlled human clinical trials to support a multitude of body function. Ashwagandha is one of the most versatile plants in existence and is a key herbal component in countless herbal stress formulas. 2. Rhodiola Rosea -A favorite among athletes and herbal practitioners, Rhodiola has a reputation as one of the world’s greatest mood and energy tonics.  It's unique array of phytochemicals have been researched for their ability to regulate critical neurotransmitters like dopamine and serotonin.  Rhodiola Rosea may help you manage stress, but it won't be sedating. 3. Ginseng (Chinese, Korean, and American) - There are 3 popular types of Ginseng used around the world; Chinese, Korean, and American.  Chinese Ginseng (Ren Shen) is considered the "king of herbs" in Traditional Chinese Medicine (TCM) and is celebrated as its' premier tonic herb.  It's active compounds, referred to as ginsenosides, are known to restore qi (pronounced "chi") or energy levels and to support a calm, alert mind. Korean Ginseng has similar properties. American Ginseng, known as the ‘Yin Ginseng’, has similar ginsenosides to its Chinese counterpart, although is traditionally viewed as a gentler tonic better suited to people with excess metabolic heat.  It can also help promote a relaxed, calm attitude among those prone to stress and overwork. 4. Holy Basil - one of the most celebrated plants in India, Holy Basil has been valued for centuries for benefiting the mind, body, and spirit.  This great tasting Ayurvedic has been researched for it's potential in the areas of stress relief and relaxation in recent times.  It's the perfect herb to help stay calm and cool in the fast-paced, modern era. 5. Eleuthero - Once thought to be a member of the Ginseng family and referred to as Siberian Ginseng, Eleuthero, is well known as one of the best adaptogenic agents ever used by man.  The epitome of an adaptogen, it supports decreased stress and fatigue while boosting energy and endurance.  Eleuthero is also used in formulas to support memory and concentration. 6. St. John's Wort- revered in Europe for it's ability to help cope with stress and support a positive outlook.  St. Johs's Wort is believed to promote serotonin, a key neurotransmitter thought to play a major role in the central nervous system and in maintaining mood balance.  7. Damiana - traditionally used as an aphrodisiac in Mexico, Damiana also has a reputation for relieving stress and anxiety. Damiana is relatively easy to find, makes a great herbal infusion, and blends well with other herbs.    Calming herbs for stress management 1. Lemon Balm - a member of the mint family, this calming herb has been used in Europe, the Mediterranean, Northern Africa, and India for thousands of years because of it's myriad benefits.  The rosemarinic acids present in Lemon Balm are believed to boost levels of GABA, a calming neurotransmitter, in the brain. Elevated GABA levels are thought to reduce the level of anxiety. 2. Lavender -one of the most common herbs or oils used for stress relief, Lavender has been used for centries for restlessness, sleep problems, nervousness, and mood balancing.  It has a fabulous aroma, tastes great, and blends well with other herbs like Lemon Balm and Chamomile. 3. Wild Milky Oats -rich in B vitamins, potassium, and magnesium Wild Milky Oats are thought to be soothing to the brain and nervous system, while at the same time being restorative to the adrenal glands and nerves.  It's the perfect herb to use to relax and calm the nerves and to tonify the endocrine system. 4. Skullcap Herb - an herb found in countless sleep and stress formulas, Skullcap Herb is believed to help combat mental chatter and relax the mind  and calm the nerves to provide a calm focus.  Some people use it before bedtime to mitigate feelings of agitation and nervous tension. 5. Chamomile - documentation of the herb for its therapeutic benefits goes back over 5000 years, and today it is still one of the most commonly consumed herbs on the planet. Chamomile tea and extracts of Chamomile are frequently used as a mild sedative to calm nerves and reduce anxiety, to help with nightmares and other sleep problems.  6. Peppermint - A common herb that you may even have in your garden, Peppermint has been steeped for hundreds of years to cool the body, calm the nerves, and help the body relax. Peppermint is the perfect herb to relax with during those hot summer evenings. 7. Magnolia -used in Chinese medicine for hundreds of years, Magnolia is believed to help manage stress by keeping the stress hormone, cortisol, in check.  It has also been shown to increase levels of GABA, a calming neurotransmitter, in mice.  It is commonly found in herbal sleep an stress formulas.  8. Passion Flower - Native to southeastern parts of the Americas, Passionflower is now grown throughout Europe and in the United States.  It has been used historically as a calming herb for anxiety, insomnia, seizures, and hysteria and is still used today to alleviate anxiety and insomnia. Scientists believe Passionflower works by increasing levels of GABA, a calming neurotransmitter, in the brain.  Although it can be used as a stand alone herb, it commonly found in herbal infusions with other herbs such as Valerian, Lemon Balm, and Chamomile to promote sleep or relaxation. 9. L - Theanine - not an herb per se, L - Theanine is an amino acid found in green and black teas. It's famous for it's ability to promote alphawave activity in the brain resulting in a feeling of relaxation and mental clarity.  L-Theanin is an excellent choice for stress support, focus, or calming down before bedtime. 10. Kava Kava -  a plant native to the western Pacific islands, Kava was consumed in ceremonies to promote relaxations.  Today, it is still commonly used to help calm anxiety, stress, and restlessness, and to treat sleeping problems. It is important to research Kava before using it, especially if you have a history of liver problems, because it has been associated with liver problems in the past.      Key Word Definitions:  Adaptogen - a nontoxic substance and usually a plant extract that is used to increase the body's ability to resist the damaging effects of stress and promote or restore homeostasis. Tonic -  A remedy believed to restore exhausted function and promote vigor and a sense of well-being. Tonics are categorized according to the organ or system on which they are presumed to act, as cardiac, kidney, adrenal, vascular etc. Neurotransmitter - a substance  that transmits nerve impulses across a synapse.  Some neurotransmitters are inhibitory (calming) such as GABA and some are exitotory (stimulating) like dopamine. Serotonin -  An important neurotransmitter that has many functions including the regulation of mood, appetite, and sleep. Serotonin also plays a role in cognitive functions, including memory and learning. The modulation of serotonin at synapses is believed to be a major factor in several classes of pharmacological antidepressants. GABA (gamma-Aminobutyric acid) - the main inhibitory or calming neurotransmitter in the brain, GABA influences our mood by reducing high levels of the hormones adrenalin, noradrenalin and dopamine. It also affects the neurotransmitter serotonin. Having sufficient GABA in our brain is linked to being relaxed and happy, while having too little GABA is associated with sleep problems, and feeling anxious, stressed, and depressed. Tryptophan - as a precursor to many neurotransmitters and neurochemicals, including serotonin and melatonin, L-tryptophan is an essential amino acid that helps improve sleep and reduce stress. Melatonin is known to help improve sleep, and serotonin is needed to improve mood and mental health. Cortisol - Cortisol is a steroid-based hormone and is synthesized from cholesterol and belongs to a group of hormones called glucocorticoids. Cortisol is made in the adrenal cortex of the adrenal gland, which is near the kidney. It is the primary stress hormone.  It's functions are to increase sugars (glucose) in the bloodstream, enhance your brain's use of glucose and to increases the availability of substances for tissue repair.  Cortisol also curbs functions that would be nonessential or detrimental in a fight-or-flight situation. It alters immune system responses and suppresses the digestive system, the reproductive system and growth processes. It alerts regions in your brain that control mood, motivation and fear. Stimulant - a substance that temporarily increases the physiologic activity of an organ, a system of organs, or that increases nervous excitability and alertness. Adrenal Gland - One of two small endocrine glands, located above each kidney. The outer part, or adrenal cortex, secretes steroid hormones (corticosteroids). The inner part, or adrenal medulla, secretes epinephrine and norepinephrine. Traditional Chinese Medicine (TCM) - The current name for an ancient system of health care from China. Traditional Chinese medicine (TCM) is based on a concept of balanced qi (pronounced "chi"), or vital energy, that is believed to flow throughout the body. Qi is proposed to regulate a person's spiritual, emotional, mental, and physical balance and to be influenced by the opposing forces of yin (negative energy) and yang (positive energy). Disease is proposed to result from the flow of qi being disrupted and yin and yang becoming imbalanced. Among the components of TCM are herbal and nutritional therapy, restorative physical exercises, meditation, acupuncture, and remedial massage. Ayurveda - The traditional Hindu system of health and medicine, based on maintaining balance among the five elements earth, air, fire, water, and  ether.  The word Ayurveda is derived from the Sanskrit words “ayur,” meaning life, and "veda,” meaning knowledge. Homeostasis - The tendency of biological systems to maintain relatively constant conditions in the internal environment while continuously interacting with and adjusting to changes originating within or outside the system.   Function Nutrition: B- vitamins (Folate, B-12, etc.) - a group of water-soluble vitamins that have varied metabolic functions and include coenzymes and growth factors. These essential nutrients allow us to convert our food into fuel, keeping us energized throughout the day. Vitamin B5 is very important for the adrenals and therefore helps with modulating stress. Folate and vitamin B12 are important for mood balance, and given the links between anxiety and depression, they may also be helpful for anxiety. B-6 - an important co-factor nutrient that may boost the production of GABA, a calming neurotransmitter.  GABA is  a key factor supporting the production of other neurotransmitters (chemical messengers) such as serotonin. When supplementing with B-6, the conenzyme or active form (pyridoxal 5'-phosphate) is superior to the isolated form (Pyridoxine), because some people can't activate pyridoxine. Folate - Folate has literally hundreds of function in the human body. It helps the body use Iron, Amino Acids, and Vitamin B-12, thus impacting energy on many levels.  It facilitates the synthesis of key neurotransmitters, such as dopamine, serotonin, and norepinephrine, that are involved in mood regulation and other important functions. Magnesium - Magnesium is needed for the production of ATP, which is the main energy-producing molecule in the body. When magnesium is deficient our cells produce less energy resulting in fatigue. Magnesium is also the fourth most abundant mineral in the human body, a necessary co-factor for hundreds of enzymes, and the most critical mineral of all for coping with stress. Lithium - Lithium is a mineral that is associated with brain function, mood, focus, and the neurotransmitters dopamine.  It has a wide range of other health benefits including immune health, bone health, and antioxidant support. Zinc - Supports the regulation of key energizing neurotransmitter, dopamine, that supports cognitive function and gives you your drive. It is also key in the metabolization of melatonin, which impacts our quality of sleep.  It's also essential for male and female reproductive health and fertility.  It also impacts strength and athletic performance by regulating the flow testosterone and inulin-like growth growth factor-1 (IGF-1). It's noteworthy that the highest concentrations of zinc found in the body is in our brain! It is a principal factor in modulating the brain and body’s response to stress and key to regulating mood.  Selenium - Support thyroid health and supports hormonal balance impacting energy on many levels. Omega 3's (Fish Oils and Algae) - Essential fatty acids that support a healthy inflammation response, combat depression and promote healthy mood and cognitive function.  Omega 3's also support adrenal function and provide hormone support.  Maintaining healthy a adrenal function is imperative for proper stress management. Lifestyle: Sleep, Diet, Personal Relationships, and Exercise all impact how we feel, how we cope with stress, and how much energy we have.  It's important to not overlook the obvious.  Sleep hygiene -  simple habits that promote quality sleep. Prioritize sleep.  Get what ever it is your body requires (7-9 hrs generally). Try to go to sleep around 10pm, when cortisol levels are at their lowest and melatonin levels are at their highest. Stop eating 2 hours before bedtime, and stop hydrating at least an hour before bedtime.  Create at dark environment to sleep in.  Avoid light before bedtime, including T.V., computers, and smart devices that emit light.  You can even dim the lights ahead of time when you're ready to unwind. Try not to hit that snooze button in the morning.  We don't want to interrupt our hormone and neurotransmitter cycles. Avoid the use stimulants, especially in the afternoon and evening.  Diet - No matter what herbs and supplements you take, you still have to support your body with healthy eating habits. Poor eating habits stress our bodies out and may even affect our mood. Eat lots of fresh fruits and especially vegetables.  Try to get the full color spectrum when selecting fruits and vegetables.  Complete nutrition is essential for stress, mood, and energy support.  We've already mentioned key vitamins, minerals, Omega 3's, etc.  Try to find foods rich in these valuable nutrients that support healthy energy levels and promote a healthy stress response.  You can reference the functional nutrition list above to narrow down your search. Exercise - Try and get a moderate amount of fresh air, sunlight, and exercise.  Don't over exercise! The goal is to promote health, and over training can deplete the adrenal and negatively impact your stress and energy levels negatively.  Do it, but don't over do it! Toxic Relationships - Social engagement is the most evolved way to cope with stress. That's why it is so important to surround yourself with people who do not normally add to your stress load.  If simply being around a particular person provokes a fight or flight response, chances are that's a Toxic Relationship!  Always look to build a strong supporting cast of good people to de-stress with.  

In this episode, we discuss nausea and vomiting of pregnancy (NVP) with a particular focus on Diclegis (doxylamine/pyridoxine).

I've been there before. Panicking in the bathroom, wishing it wasn't true. It's a hard question to try to answer because nothing I say is going to make you feel magically better. If you're already sick then more than likely it's going to continue to some extent. But learning what works best for you and fighting it everyday could mean the difference between hospitalization and infection, or staying home. If you haven't done it already, I highly suggest you get a Doctor's appointment, the soonest available. Ask for medication and start taking it round the clock right away. If you haven't gotten sick yet, you could just have it on hand until it starts. For some people it's violent from the start. Keeping yourself out of a bad cycle of dehydration and vomiting and not eating is the overall goal. Medication to ask about: Zofran: (prescription) (ondansetron) Anti-emetic (it helps control the vomiting) Unisom: (Over the counter) (doxylamine) anti-histamine (helps control the nausea) Diclectin: (prescription) (Pyridoxine/doxylamine) which is unisom and B6 together in a time release capsule. Phenergan: (prescription) (Promethazine), (I.V., suppositories, pill) Reglan: (prescription) (Metoclopramide) dopamine-receptor antagonist. It can help with nausea and vomiting by helping with gastric emptying. It's often given to people with GERD. However, one adverse effect to watch out for is called tardive dyskinesia. It can also make you feel tired, restless and anxious. Gabapentin: (prescription) (Neurontin) anticonvulsant and analgesic, usually given to control seizure disorders or neurological pain. This is still being trialed and is not commonly prescribed. Adverse effects for pregnancy are unknown. Dealing with constipation as a side effect of medication, notably Zofran. You can ask your doctor for a stool softener to be proactive and try to prevent constipation from happening. You can also try milk of magnesia or another kind of magnesium pill or liquid. That can help in numerous ways, including getting some much needed magnesium. If you're already constipated, I would suggest doing more than that to try to get ahead of the problem. Glycerin suppositories (can be found in more drug stores in the U.S.) Enemas (like Fleets brand enema): It comes in a self contained package with saline. One time use. Willard water Saline warm water Magnesium oil: You can make it yourself. It's actually not an oil but a solution of equal parts magnesium chloride and filtered water. What would you tell someone with HG who just found out they were pregnant?  

Multivitamins for Men and Women are recommended for every athlete and the majority of adults. Athletes need multivitamins because of their increased metabolic demand. It is important to take a multivitamin that has the nutrients in their proper forms so that they can be absorbed.   You need to consider your total nutrient intake to be a combination of diet and supplements. Supplements are just that, a supplement to an already nutrient dense diet. Micronutrients should not just be obtained from a multivitamin.   It is very important to take a high quality multivitamin that contains nutrients in the right form, which would be absorbable forms in a dosage that matters.   When looking at the label on Triton Nutrition's Basic MultiPro for Men, you see that the minerals are listed. The way humans are designed to absorb minerals is in the form of plants. Plants that pull minerals out of the ground and then we eat the plants. Cheap Multivitamins are nothing more than crushed up rocks and dirt and are bodies were not designed to absorb nutrients that way. When plants pull the minerals out of the ground, they actually couple them with an amino acid. This is called chelation. TRAACS minerals, which are used in both the Basic MultiPro for Men and in the Basic MultiPro for Women, is a real amino acid chelate system. So, this puts the minerals in the most absorbable form. This means when you swallow the multivitamin, it is actually absorbed and enters your blood system.   For example, when looking at B Vitamins, not all B Vitamins forms are created the same. So Vitamin B6, Pyridoxine, can come in the form Pyridoxine HCl , which is very cheap and you can find this in cheap multivitamins. This form is very difficult to absorb. The form of B6 called Pyridoxine 5'-Phosphate is a superior form and is easily absorbed. This is located in Triton Nutrition's Multipro.   Another example is Vitamin B2, Riboflavin. The form of Riboflavin called Riboflavin HCl is cheap, but very difficult to absorb. Riboflavin 5'-Phosphate is the superior form, which is readily absorbed by your body.   So you see, these are two examples of superior forms of nutrients and why spending money on inexpensive multivitamins is a waste because they are not being absorbed properly. It is very important to take a superior, high quality multivitamin that contains nutrients in forms that can be absorbed by your body.   You can learn about Spectracell Micronutrient Testing that allows you to identify your micro-nutrient deficiencies at Triton Nutrition. Triton Nutrition offers many Multivitamin supplements to suit your needs. They offer specific multivitamins for males and females or for those who may prefer a liquid form. If you are an athlete, there are multivitamins specifically for you.   by Robert Seik, PharmD

B Vitamins have many important functions and are responsible for many biochemical reactions in the body. One very important function is B Vitamins for Energy. Without a full spectrum of B Vitamins we do not have energy. B Vitamins are necessary as co-factors to make hormones and neurotransmitters so that are brain can communicate and it affects our mood. We also need B Vitamins to help us detoxify.   The important thing is to make sure you get your B vitamins from a very nutrient dense diet. We promote the food first model. We talk about the Paleo diet and how it can help you achieve metabolic efficiency, but we often have to add supplements because our food does not have as many nutrients as we need. Also, athletes burn through these nutrients particularly because of energy expenditure and that's when B Vitamins are depleted.   There are times when athletes can over consume protein and it is important to know that protein depletes B Vitamins. When we have protein metabolism activated, B Vitamins are co-factors that are taking the amino acids from protein that is being broken down. These amino acids are then being used to make over 65,000 enzymes that our liver produces, to make tissue that need to be repaired from use.   Triton Nutrition has a special form called B-Energy Complex that follows GCMP standards and that delivers the nutrients in a form that is absorbable. For example Vitamin B-2, which is called riboflavin. Riboflavin HCl (Riboflavin Hydrochloride) is very inexpensive to produce and you will often see this form in many poor quality supplements, but it is poorly absorbed. Riboflavin-5'-Phosphate, which is the best form for us to absorb and utilize, which is the most abundant form found in nutrient dense foods is the form that Triton Nutrition uses.   Vitamin B-6 or Pyridoxine is often found in the form of Pyridoxine HCl in poor quality and cheap supplements. Again, this form is poorly absorbed so you aren't actually taking in the amount that you think you are. Triton Nutrition uses Pyridoxal-5'-Phosphate, which is the active form.   Vitamin B-1 or Thiamine can be found in the form Thiamine HCl, which is actually quite usable, but you also need to take the fat soluble form, which gets into the brain and that's called Benfotiamine. We need B Vitamins in the brain to make neurotransmitters. There is also Vitamin B-12 known as methylcobalamin, which is the active form of Vitamin B-12. If someone is very low in Vitamin B-12 they may need to take a sublingual tablet in order to boost their levels. Vitamin B-12 in the form of methylcobalamin can also be found in Triton Nutrition's NeuroKinetic Cream. The reason it is called NeuroKinetic Cream is because it has the necessary ingredients to make neurotransmitters. NeuroKinetic Cream also has 5-MTHF, a special form of Folic Acid.   The B-Energy Complex also contains Folic Acid, B-3 in two forms and B-5. So when looking for a B Vitamin Complex you want to make sure you have the active forms of the B Vitamins.   by Robert Seik, PharmD

Authors Dr Sidney Gospe (Division of Pediatric Neurology and Professor of Neurology and Pediatrics, University of Washington, Seattle Children's Hospital, Seattle) and Professor Bernard Schmitt (Division of Clinical Neurophysiology/Epilepsy, University Children's Hospital, Zurich) discuss the issues of Pyridoxine-dependent epilepsy and related conditions and how to treat them with Editor In Chief of Developmental Medicine and Child Neurology, Dr Peter Baxter. Related journal articles: Seizures and paroxysmal events: symptoms pointing to the diagnosis of pyridoxine-dependent epilepsy and pyridoxine phosphate oxidase deficiency http://www3.interscience.wiley.com/cgi-bin/fulltext/123334976/PDFSTART Pyridoxine-dependent epilepsy and pyridoxine phosphate oxidase deficiency: unique clinical symptoms and non-specific EEG characteristics http://www3.interscience.wiley.com/cgi-bin/fulltext/123349115/PDFSTART