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In this CME podcast episode, Dr. Andrew Cutler interviews Dr. Phillip Coffin, Director of the Center on Substance Use and Health in San Francisco, CA, about the management of stimulant use disorders. They explore the challenges of treatment and highlight the importance of harm reduction strategies to enhance patients' quality of life. CME credit is available to NEI Members only. Target Audience: This activity has been developed for the healthcare team or individual prescriber specializing in mental health. All other healthcare team members interested in psychopharmacology are welcome for advanced study. Learning Objectives: After completing this educational activity, you should be better able to: Summarize pharmacologic and behavioral treatment strategies for stimulant use disorders, particularly methamphetamine and cocaine Evaluate the evidence base for current and investigational medications used in clinical trials and real-world settings Apply harm reduction principles and integrated care models to improve outcomes for patients with stimulant use disorders in diverse clinical settings Accreditation: In support of improving patient care, this activity has been planned and implemented by HMP Education and Neuroscience Education Institute (NEI). HMP Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. Activity Overview: This activity is available with synchronized audio and is best supported via a computer or device with current versions of the following browsers: Mozilla Firefox, Google Chrome, or Safari. A PDF reader is required for print publications. A post-test score of 70% or higher is required to receive CME/CE credit. Estimated Time to Complete: 1 hour Released: June 18, 2025* Expiration: June 17, 2028 *NEI and HMP Education maintain a record of participation for six (6) years. CME/CE Credits and Certificate Instructions: After listening to the podcast, to take the optional posttest and receive CME/CE credit, click: https://nei.global/POD25-02. Credit Designations: The following are being offered for this activity: Physician: ACCME AMA PRA Category 1 Credits™ HMP Education designates this enduring material for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Nurse: ANCC contact hours This continuing nursing education activity awards 1.00 contact hour. Provider approved by the California Board of Registered Nursing, Provider #18006 for 1.00 contact hour. Nurse Practitioner: ACCME AMA PRA Category 1 Credit™ American Academy of Nurse Practitioners National Certification Program accepts AMA PRA Category 1 Credits™ from organizations accredited by the ACCME. The content in this activity pertaining to pharmacology is worth 1.00 continuing education hour of pharmacotherapeutics. Pharmacy: ACPE application-based contact hours This internet enduring, knowledge-based activity has been approved for a maximum of 1.00 contact hour (.10 CEU). The official record of credit will be in the CPE Monitor system. Following ACPE Policy, NEI and HMP Education must transmit your claim to CPE Monitor within 60 days from the date you complete this CPE activity and are unable to report your claimed credit after this 60-day period. Ensure your profile includes your DOB and NABP ID. Physician Associate/Assistant: AAPA Category 1 CME credits HMP Education has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credits for activities planned in accordance with the AAPA CME Criteria. This internet enduring activity is designated for 1.00 AAPA Category 1 credit. Approval is valid until June 17, 2028. PAs should only claim credit commensurate with the extent of their participation. Psychology: APA CE credits Continuing Education (CE) credits for psychologists are provided through the co-sponsorship of the American Psychological Association (APA) Office of Continuing Education in Psychology (CEP). The APA CEP Office maintains responsibility for the content of the programs. This activity awards 1.00 CE Credit. Social Work: ASWB-ACE CE credits As a Jointly Accredited Organization, HMP Education is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. Regulatory boards are the final authority on courses accepted for continuing education credit. Social workers completing this internet enduring course receive 1.00 general continuing education credit. Non-Physician Member of the Healthcare Team: Certificate of Participation HMP Education awards hours of participation (consistent with the designated number of AMA PRA Category 1 Credit™) to a participant who successfully completes this educational activity. Peer Review: The content was peer-reviewed by an MD, LFAPA specializing in psychiatry, forensic, addiction to ensure the scientific accuracy and medical relevance of information presented and its independence from commercial bias. NEI and HMP Education takes responsibility for the content, quality, and scientific integrity of this CME/CE activity. Disclosures: All individuals in a position to influence or control content are required to disclose any relevant financial relationships. Any relevant financial relationships were mitigated prior to the activity being planned, developed, or presented. Disclosures are from the original live presentation, unless otherwise noted. Faculty Author / Presenter Andrew J. Cutler, MD Clinical Associate Professor, Department of Psychiatry and Behavioral Sciences, Norton College of Medicine, State University of New York Upstate Medical University, Syracuse, NY Chief Medical Officer, Neuroscience Education Institute, Malvern, PA Consultant/Advisor: AbbVie, Acadia, Alfasigma, Alkermes, Axsome, Biogen, BioXcel, Boehringer Ingelheim, Brii Biosciences, Cerevel, Corium, Delpor, Evolution Research, Idorsia, Intra-Cellular, Ironshore, Janssen, Jazz, Karuna, Lundbeck, LivaNova, Luye, MapLight Therapeutics, Neumora, Neurocrine, NeuroSigma, Noven, Otsuka, Relmada, Reviva, Sage Therapeutics, Sumitomo (Sunovion), Supernus, Takeda, Teva, Tris Pharma, VistaGen Therapeutics Speakers Bureau: AbbVie, Acadia, Alfasigma, Alkermes, Axsome, BioXcel, Corium, Idorsia, Intra-Cellular, Ironshore, Janssen, Lundbeck, Neurocrine, Noven, Otsuka, Sumitomot (Sunovion), Supernus, Takeda, Teva, Tris Pharma, Vanda Data Safety Monitoring Board (DSMB): COMPASS Pathways, Freedom Biosciences Faculty Author / Presenter Phillip Coffin, MD, MIA Director of Center on Substance Use and Health, San Francisco Department of Public Health, San Francisco, CA No financial relationships to disclose. The remaining Planning Committee members, Content Editors, Peer Reviewer, and NEI planners/staff have no financial relationships to disclose. NEI and HMP Education planners and staff include Gabriela Alarcón, PhD, Ali Holladay, Andrea Zimmerman, EdD, CHCP, Brielle Calleo, Stephen Daniels and Bahgwan Bahroo, MD, LFAPA. Disclosure of Off-Label Use: This educational activity may include discussion of unlabeled and/or investigational uses of agents that are not currently labeled for such use by the FDA. Please consult the product prescribing information for full disclosure of labeled uses. Cultural Linguistic Competency and Implicit Bias: A variety of resources addressing cultural and linguistic competencies and strategies for understanding and reducing implicit bias can be found in this handout—download me. Accessibility Statement For questions regarding this educational activity, or to cancel your account, please email customerservice@neiglobal.com. Support: This activity is supported solely by the provider, NEI.
Looking fit and being healthy are two different things; and the fitness world is actaully pretty toxic. Stmulants, supplements, fake foods and protein bars could be wrecking your gut, and it often gets missed because no one told you it's alla. scam. We're talking with Brian Keane, who was the definition of "fit out the outside". He was a pro bodybuilder and ultra endurance athlete who's gut was being ripped apart on the inside. TOPICS DISCUSSED IN THIS EPISODE: The dark side of the multi billion dollar fitness industry How exercise, overtraining and "fitness foods" are horrible for your health Stimulants, pre-workouts and toxic fitness supplements Food, diets and nutrition Counting calories vs. counting chemicals Sleep and recovery Getting the body you want and staying healthy doing it More from Mito Red Light: Instagram: @brian_keane_fitness Website: briankeanefitness.com Leave us a Review: https://www.reversablepod.com/review Need help with your gut? Visit my website gutsolution.ca to join a program: Get help now Contact us: reversablepod.com/tips FIND ME ON SOCIAL MEDIA: Instagram Facebook YouTube
Episode 192: ADHD Treatment. Jordan Redden (MSIV) explains the treatment of ADHD. Dr. Bustamante adds input about pharmacologic and non-pharmacologic treatments. Dr. Arreaza shares the how stimulants were discovered as the treatment for ADHD. Written by Jordan Redden, MSIV, Ross University School of Medicine. Comments and edits by Isabelo Bustamante, MD, and Hector Arreaza, MD. You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.Introduction.ADHD is a chronic neurodevelopmental condition characterized by inattention, impulsivity, and/or hyperactivity. While it's often diagnosed in childhood, symptoms can persist well in adulthood. The treatment for ADHD is multifaceted. It often includes medication, behavioral therapy, environmental modifications, and sometimes educational interventions which are especially effective in younger patients. Ongoing evaluation is needed during treatment. Treatment needs adjustments over time.Starting with medications: Stimulants are the most well-studied and effective pharmacologic treatment for ADHD. These include methylphenidate-based medications such as Ritalin, Concerta, and Focalin, and amphetamine-based options, like Adderall, Vyvanse, and Dexedrine. Discovery of stimulants for ADHD> Dr. Charles Bradley discovered stimulants as the treatment for ADHD around 1937. ADHD did not have a name at that time, but it was known that some children had behavioral problems related to poor attention and inability to control their impulses, but they were still intelligent. Dr. Bradley was a psychiatrist who was working in the Bradley Hospital (Rhode Island), he was studying these children and, as part of his experiments, they developed severe headaches. He gave “Benzedrine” (a decongestant) to his pediatric patients to treat severe headaches, and he discovered that Benzedrine improved academic performance and interest in school and improved disruptive behavior in some children.How do stimulants work.Stimulants work primarily by increasing dopamine and norepinephrine levels in the brain, which helps improve focus, attention span, and impulse control. They typically show a rapid onset of action and can lead to noticeable improvements within the first few days of use. Dosing is individualized and should start low with gradual titration. Side effects can include reduced appetite, insomnia, headaches, increased heart rate, and emotional lability.Types of stimulants. Stimulants come as short acting and long acting. They can come as a tablet, liquid, patch, or orally disintegrating tablet. After the discovery of Benzedrine as a possible treatment for ADHD, more research was done over the years, and Ritalin became the first FDA-approved medication for ADHD (1955). The list of medications may seem overwhelming, but there are only two types of stimulants used to treat ADHD: methylphenidate and amphetamine. Long-acting stimulant medications are often preferred for their consistent symptom control and lower potential for misuse. Vyvanse (lis-dexa-mfetamine) is a widely used long-acting amphetamine-based option. As a prodrug, it remains inactive until metabolized in the body, which results in a smoother onset and offset of action and may reduce the risk of abuse. This extended duration of effect can help patients maintain focus and regulate impulses throughout the day without the peaks and crashes sometimes seen with shorter-acting formulations. Of note, Vyvanse is also approved for Binge Eating Disorder. Many of these medications are Schedule II controlled substances, so to prescribe them you need a DEA license. Other long-acting options include Concerta, an extended-release methylphenidate, as well as extended-release versions of Adderall and Focalin. These are especially helpful for school-aged children who benefit from once-daily dosing, and for adults who need sustained attention during work or academic activities. The choice between short- and long-acting stimulants depends on individual response, side effect tolerance, and daily routine.For patients who cannot tolerate stimulants, or for those with contraindications such as a history of substance misuse or certain cardiac conditions, non-stimulant medications are an alternative. One of the most used is atomoxetine, which inhibits the presynaptic norepinephrine transporter (NET). This leads to increased levels of norepinephrine (and to a lesser extent dopamine). Guanfacine or clonidine are alpha-2A adrenergic receptor agonists that lead to reduced sympathetic outflow and enhanced prefrontal cortical function, improving attention and impulse control. These alpha agonists are particularly useful in younger children with significant hyperactivity or sleep disturbances.Non-pharmacologic treatments.Behavioral therapy before age 6 is the first choice, after that, medications are more effective than BH only, and as adults again you use CBT.Medication is often just one part of a broader treatment plan. Behavioral therapy, especially in children, plays a critical role. Parent-training programs, positive reinforcement systems, and structured routines can significantly improve functioning. And for adolescents and adults, cognitive-behavioral therapy (CBT) is particularly helpful. CBT can address issues like procrastination, time management, emotional regulation, and self-esteem which are areas that medication doesn't always touch.Using medications for ADHD can be faced with resistance by parents, and even children. There is stigma and misconceptions about mental health, there may be concerns about side effects, fear of addiction, negative past experiences, and some parents prefer to treat ADHD the “natural” way without medications or only with supplements. All those concerns are valid. Starting a medication for ADHD is the first line of treatment in children who are 6 years and older, but it requires a shared decision with parents and patients. Cardiac side effects are possible with stimulants. EKG may be needed before starting stimulants, but it is not required. Get a personal and family cardiac history, including a solid ROS. Benefits include control of current condition and treating comorbid conditions.The presentation of ADHD changes as the person goes through different stages of life. For example, you may have severe hyperactivity in your school years, but that hyperactivity improves during adolescence and impulsivity worsens. It varies among sexes too. Women tend to present as inattentive, and men tend to be more hyperactive. ADHD is often underdiagnosed in adults, yet it can significantly impact job performance, relationships, and mental health. In adults, we often use long-acting stimulants to minimize the potential for misuse. And psychotherapy, particularly CBT or executive functioning coaching, can be life-changing when combined with pharmacologic treatment. There are several populations where treatment must be tailored carefully such as pregnant patients, individuals with co-occurring anxiety or depression, and those with a history of substance use. For example, atomoxetine may be preferred in patients with a history of substance misuse. And in children with coexisting oppositional defiant disorder, combined behavioral and pharmacologic therapy is usually more effective than either approach alone.Comorbid conditions.Depression and anxiety can be comorbid, and they can also mimic ADHD. Consult your DSM-5 to clarify what you are treating, ADHD vs depression/anxiety.Treatment goes beyond the clinic. For school-aged children, we often work closely with schools to implement 504 plans or Individualized Education Programs (IEPs) that provide classroom accommodations. Adults may also benefit from workplace strategies like structured schedules, noise-reducing headphones, or even coaching support. Ongoing monitoring is absolutely essential. We assess side effects of medication, adherence, and symptom control. ***In children, we also monitor growth and sleep patterns. We often use validated rating scales, like the Vanderbilt questionnaire for children 6–12 (collect answers from two settings) or Conners questionnaires (collect from clinician, parents and teachers), to track progress. And shared decision-making with patients and families is key throughout the treatment process.To summarize, ADHD is a chronic but manageable condition. Effective treatment usually involves a combination of medication and behavioral interventions, tailored to the individual's needs. And early diagnosis and treatment can significantly improve quality of life academically, socially, and emotionally.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed., text rev. (DSM-5-TR). Washington, DC: American Psychiatric Association; 2022. CHADD (Children and Adults with Attention-Deficit/Hyperactivity Disorder). Understanding ADHD. Accessed May 2025. https://chadd.org National Institute for Health and Care Excellence (NICE). Attention Deficit Hyperactivity Disorder: Diagnosis and Management. NICE guideline [NG87]. Updated March 2018. Accessed May 2025. https://www.nice.org.uk/guidance/ng87 Pliszka SR; AACAP Work Group on Quality Issues. Practice parameter for the assessment and treatment of children and adolescents with attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry. 2007;46(7):894–921. doi:10.1097/chi.0b013e318054e724 Subcommittee on Children and Adolescents with Attention-Deficit/Hyperactivity Disorder, Steering Committee on Quality Improvement and Management. Clinical practice guideline for the diagnosis, evaluation, and treatment of attention-deficit/hyperactivity disorder in children and adolescents. Pediatrics. 2019;144(4):e20192528. doi:10.1542/peds.2019-2528 Texas Children's Hospital. ADHD Provider Toolkit. Baylor College of Medicine. Accessed May 2025. https://www.bcm.edu Wolraich ML, Hagan JF Jr, Allan C, et al. Attention deficit hyperactivity disorder in children and adolescents: Overview of treatment and prognosis. UpToDate. Published 2024. Accessed May 2025.https://www.uptodate.comThe History of ADHD and Its Treatments, https://www.additudemag.com/history-of-adhd/Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.
Stimulant comme une idée neuve, apaisant comme une matinée d'hiver au coin du feu… connaissez-vous le maté ? Boisson traditionnelle originaire d'Argentine, Eva Fermeli l'a découvert lors d'un échange universitaire en Argentine. Véritable symbole de partage et boisson qui rassemble, elle a été séduite.Alors au retour de cet échange, Eva imagine Neo·ka, une marque d'infusions de maté bio, pensées pour nos palais curieux et nos rythmes modernes. Pour l'adapter aux us et coutumes français, elle a même développé plusieurs saveurs autour de cette plante sacrée avec fraîcheur, exigence et créativité, comme le maté cacao-piment !Au menu de cet épisode :
Nick Walker Robbed? Super Charging TRT, Physique Critique, Test to DHT Ratio, Managing Fatigue On a Cut - Blood, Sweat & Gear 300 w/ Coaches Skip Hill, Andrew Berry, Scott McNally 0:00 Teaser - Anavar on TRT 0:45 Intro, Advertisers, Patreon 1:30 Nick Walker vs Derek Lunsford 14:25 What Steroids To Add To TRT? 16:00 6 wk experiments on TRT Plus 17:20 Just Increase Test? 24:00 Shout Out To Jordan - Member of Think BIG Facebook Group 25:30 Physique Critique 30:30 Winstrol is the Old Tren 31:40 Test to DHT Ratio 33:40 Macro Ratio to start diet 37:00 Managing fatigue on a Cut Diet 38:45 Keeping Neat Cardio High 40:15 Stimulants and why to be careful with them in dieting 44:30 NEAT Cardio, HIIT & High Intensity 52:15 When to add Anadrol in a bulk 55:40 Do you pull Primo before a show? 56:40 Skip's word of the day 58:05 Skip is 9 wks out! Reach out to the guys for coaching !
Today, we're tackling a big question: How young is too young to treat children with medication for ADHD?CME: Take the CME Post-Test for this EpisodePublished On: 05/12/2025Duration: 14 minutes, 36 secondsJoshua Feder, MD, and Mara Goverman, LCSW, have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.
durée : 00:02:36 - Le purin de consoude est un stimulant pour les végétaux qui sert d'engrais aux plantes et fertilise le sol. - .
durée : 00:05:22 - Avec sciences - par : Alexandre Morales - Dans un papier de la revue Science Advances, des chercheurs affirment avoir fait percevoir une nouvelle couleur à cinq personnes en stimulant leur rétine grâce à un laser.
Welcome to a preview of the 19th Ask Me Anything (AMA) episode, part of Huberman Lab Premium. If you're an existing Huberman Lab Premium member, you can log in to access the full episode at https://hubermanlab.supercast.com. You can access the transcript here. If you're not a member, you can learn more and join Huberman Lab Premium at https://www.hubermanlab.com/premium. ROKA Wind Down™: https://www.roka.com/huberman Huberman Lab Essentials: https://go.hubermanlab.com/essentials Timestamps 00:00:00 Introduction 00:00:15 The Importance of Light Management for Sleep 00:00:58 Huberman Lab Premium 00:01:33 Research Funding & Matching Donations 00:03:05 Subscription Details & Benefits 00:03:48 Protein Sources 00:05:18 Comparing Whey Protein, Bone Broth, & Collagen 00:10:08 Protein Intake Recommendations 00:14:22 Whey Protein & Skin Health 00:17:42 Conclusion In the full AMA episode, we cover: Creatine & Water Retention Creatine for Brain Health Creatine Use in Teenagers Safety & Effects of Smelling Salts Other Stimulants: Caffeine & Nicotine Prescription Stimulants & Cognitive Enhancers Disclaimer & Disclosures
In this Huberman Lab Essentials episode, I explain how to build endurance and describe targeted protocols to enhance different types of endurance. I discuss how endurance—the ability to sustain effort—requires the coordination of physical and mental systems driven by energy availability, brain willpower, and specific training adaptations in the muscles, heart, lungs and neurons. I explain conditioning protocols designed to enhance four types of endurance, from long-duration steady state to muscular endurance and high-intensity intervals, and how each training style triggers unique adaptations in the body and brain, such as improved mitochondrial function and oxygen utilization. Additionally, I highlight the crucial role of hydration and electrolytes, which are essential for neural function and influence the brain's willpower to sustain effort. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Follow Huberman Lab Instagram Threads X Facebook TikTok LinkedIn Timestamps 00:00:00 Huberman Lab Essentials; Build Endurance 00:00:50 Energy Sources, ATP, Oxygen 00:04:14 Neurons & Willpower, Glucose & Electrolytes 00:09:19 Heart, Lungs; Physiology & Performance Limiting Factors 00:10:35 Sponsor: AG1 00:12:30 Muscular Endurance, Protocol, Concentric Movements, Mitochondria 00:19:10 Sponsors: LMNT & Eight Sleep 00:22:00 Long-Duration Endurance, Efficiency, Mitochondria, Capillaries 00:25:54 High-Intensity Interval Training (HIIT), Anaerobic Endurance, Protocol 00:32:33 High-Intensity Aerobic Endurance, Adaptations 00:35:30 Sponsor: Function 00:37:26 Brain & Body Adaptations, Heart 00:40:40 Hydration, Tool: Galpin Equation 00:42:21 Supplements, Stimulants, Magnesium Malate 00:43:11 Recap & Key Takeaways Disclaimer & Disclosures
Time to have the talk about stimulants, their benefits, as well as their side effects.
I'm delighted to bring you Episode 4 of Season 3 of The Luke Coutinho Show, featuring Dr. Maulik Parekh—a leading Interventional Cardiologist, Head of the TAVR and Structural Heart Programme, and Consultant at the Sir H. N. Reliance Foundation Hospital and Research Centre.Tune in to discover:Dr. Maulik's journey into cardiology: From aspiring architect to pioneering cardiologist, and healing through groundbreaking structural heart interventions for all agesUnderstanding the rising incidence of heart diseases: Why India is facing an alarming rise in heart issues among the young, driven by genes, lifestyle, and stressGenetics vs. Epigenetics: How can you outsmart your family history with the right choicesPreventive heart health: Recommended screenings for all age groups and mindful use of health tracking devicesImpact of chronic stress and emotions on heart health: How stress and emotions can disrupt rhythms, weaken muscles, and turn minor plaques into major heart attacksMeditation and body awareness: Learn to deepen your connection to heart health by enhancing sensitivity to your body's pulse and cardiovascular stateVaping, stimulants, and heart health: Vaping and stimulants hijack your heart's natural rhythm, leading to long-term cardiac stress and dysfunctionAnd much more…Chapters:00:00 - Introduction and Dr. Maulik's Journey06:55 - Rise in Young Heart Attacks10:35 - Genetics vs. Epigenetics13:23 - Essential Heart Health Screenings20:09 - Health Gadgets: Helpful or Stressful?23:51 - Dr. Maulik's Personal Health Routine30:26 - How Stress Damages Your Heart34:38 - Broken Heart Syndrome Explained37:06 - Meditation and Body Awareness40:28 - Vaping, Stimulants & Heart Health44:26 - The Four C's for Heart Health
Send us a textSarah welcomes Austin Stout back to The Beyond Condition Podcast for an episode deepdiving on all things sleep.We get stuck into sleep quality, the benefits of a sleep routine and how we can understand the importance of sleep more as bodybuilders.Discussions include:*Hyper-fixation and sleep data*Circadian rhythm*Sleep routine*Routine and structure*Digestion*Light and blue light blockers*Naps and timings*Sleep apnea and deprivation*Mouth taping and snoring*Supplementation and pharmaceutical drugs*Stimulants and caffeine*Coaching*PED's*Bodybuilding preps*Life outside bodybuildingFind Austin on Instagram @austin_st8Watch it here: https://youtu.be/uZj5-yNILJkGet in touch and share this episode @sarahparker_bb
Brain health has emerged as one of the defining challenges of our time, driven by a double whammy of soaring rates of neurological conditions such as stroke, dementia, and Parkinson's disease linked to ageing populations, alongside a rise in mental health issues among young people. To confront this escalating crisis, an initiative called Brain House was launched earlier this year at Davos, Switzerland. The initiative seeks to drive a unified global effort, bringing together stakeholders—from mental health experts to philanthropic and for-profit investors—to prioritise brain health like never before. Leading this movement is George Vradenburg, chairman and co-founder of the Davos Alzheimer's Collaborative (DAC). Vradenburg told Biznews in an interview that it is crucial to reduce risk factors, build brain resilience, and harness technology and AI to transform brain health outcomes. He emphasised that new technologies, such as AI, have consistently been adapted to extend the capabilities of our brains. “These technologies are powerful stimulants to brain plasticity and to brain health,” he remarked. A Health for Africa programme is set to launch at the G20 summit in South Africa this November.
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
In this episode, I discuss amphetamine/dextroamphetamine pharmacology, adverse effects, drug interactions, and much more. Stimulants like Adderall are well known to cause insomnia. This adverse effect can be affected by the timing of the dose. Lack of growth and poor appetite are two important things to monitor in pediatric patients taking Adderall. Changes in the pH of the stomach/gut can alter the absorption of Adderall. I discuss this in greater detail in this podcast episode. Cardiovascular monitoring is essential with the use of stimulants like Adderall. Pulse and heart rate are two important vital signs to assess.
Prescription Stimulant Use, Misuse, and Use Disorder Among US Adults Aged 18 to 64 Years JAMA Psychiatry This study examined the prevalence of prescription stimulant use, prescription stimulant misuse, and prescription stimulant use disorder (PSUD) among adults aged 18 to 64 years in the US. Researchers found that 25.3% of adults in the study reported misuse, and 9.0% had PSUD. Among those with PSUD, 72.9% solely used their own prescribed stimulants, 87.1% used amphetamines, 42.5% reported no misuse, and 63.6% had mild PSUD. The prevalence of misuse was 3.1 times higher and the prevalence of PSUD was 2.2 times higher among those using prescription amphetamines than among those using methylphenidate. Regardless of prescription stimulant misuse status, screening for and treating PSUD is needed for US adults aged 18 to 64 years using prescription stimulants, especially those receiving prescription amphetamines. Read this issue of the ASAM Weekly Subscribe to the ASAM Weekly Visit ASAM
My guest is Dr. Chris Palmer, M.D., a board-certified psychiatrist and professor at Harvard Medical School. He explains how specific nutrition, exercise, supplement-based, and other factors can improve mitochondrial health and thereby provide relief from adult and childhood ADHD, bipolar disorder, schizophrenia, and symptoms of autism. We discuss mitochondrial biology, whether vaccines can impact inflammation and mitochondrial health, and the potential ramifications. We also review creatine, methylene blue, and urolithin A, as well as the role of B vitamins and iron in treating depression. By the end of this episode, you will understand the powerful link between metabolic health and mental health, and the lifestyle, dietary, and other factors you can leverage to help overcome common mental health challenges and disorders. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Our Place: https://fromourplace.com/huberman LMNT: https://drinklmnt.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00:00 Dr. Chris Palmer 00:02:15 Integrating Metabolic, Mental & Physical Health; Childhood Trauma & Risk 00:10:46 Sponsors: Our Place & LMNT 00:13:44 Depression Causes, Molecule Model?, Neuroplasticity?; Metabolism 00:22:20 Mitochondrial Functions, Stress Response, Mental Health 00:31:09 Sponsors: AG1 & Eight Sleep 00:33:59 Mitochondrial Health & 6 Pillars of Lifestyle Medicine 00:39:38 Stimulants, Mitochondria, Dopamine; Alcohol 00:45:47 Nicotine; Substance Use, Metabolic Health & Disease 00:52:23 Children, Energy & Metabolic Function; Diseases of Aging & Mental Disorders 00:59:18 Sponsor: Function 01:01:06 Diet & Metabolism; Ultra-Processed Foods, Additives, GRAS 01:09:30 Rebellious Spirit, Ultra-Processed Foods & Food Industry Funding 01:19:14 Ketogenic Diet, Epilepsy, Schizophrenia, Bipolar 01:22:52 Ketogenic Diet, Fasting & Mitochondria; Gut Microbiome, Brain Metabolism 01:30:06 Low-Fat Diets; Tool: Occasional Fasts; Ketogenic Diet; Intermittent Fasting 01:38:40 Nutrition Research, Food Industry Lobbyists; Ultra-Processed Foods, Addiction 01:46:55 Creatine & Mitochondrial Health 01:52:34 Methylene Blue & Mitochondria; Serotonin Syndrome 02:02:58 Urolithin A, Mitochondria Function; Supplements & Appropriate Use 02:11:14 Vitamin Deficiencies, Iron Deficiency 02:16:06 Vitamin B12 & Folate Deficiency, Autoimmune Disorders 02:24:48 Mental Illness & Root Causes 02:29:02 Vaccines, Inflammation, Mitochondria, Autism 02:39:17 Neurodevelopmental Disorder Onset & Follow-Up 02:45:31 Vaccines, Autism, Future Research; Mother Obesity & Diabetes 02:51:23 Father Obesity & Autism; Poor Metabolic Health, Blood Biomarkers 02:56:44 Assessing Metabolic Health & Biomarkers; National Institutes of Health (NIH) 03:02:59 Future Directions, Bridging Mental & Physical Health 03:09:27 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
Dr. Gillett, James O'Hara and Jim Lavalle scientifically dismantle biohacking, longevity, & peptides. Jim Lavalle: James LaValle is an internationally recognized clinical pharmacist, author, board-certified clinical nutritionist, and expert and educator in integrative and precision health. James is best known for his expertise in personalized integrative therapies uncovering the underlying metabolic issues that keep people from feeling healthy and vital. A thought leader in drug/nutrient depletion issues he has published 4 books and 3 databases in this area alone. He has over 35 years of experience integrating natural and integrative therapies into various medical and business models. His latest research is in drug-induced microbiome disruption.Follow Jim:► https://www.instagram.com/therealjimlavalle/► https://www.instagram.com/metabolic_elite/More about Jim:► https://www.jimlavalle.com/► http://www.metaboliccode.com/► www.metabolicelite.co00:00 Intro01:47
In this episode, we dive into the complex relationship between ADHD and menopause, exploring how hormonal shifts can intensify ADHD symptoms. Many women with ADHD find that perimenopause brings heightened struggles with focus, executive functioning, and emotional regulation. As estrogen declines, so does dopamine—an essential neurotransmitter for motivation and attention—worsening ADHD-related brain fog, forgetfulness, and mental fatigue. These changes can feel overwhelming, but understanding the biological connections between ADHD and menopause is key to managing them effectively.Despite the challenges, ADHD isn't just a collection of deficits; it also comes with unique strengths such as creativity, resilience, and dynamic problem-solving. However, during perimenopause, declining estrogen can make it harder to harness these gifts. Women may feel more scattered, struggle with organization, or experience mood swings that disrupt daily life. Fortunately, effective treatments can help restore balance. Stimulant medications remain a cornerstone of ADHD management, but cognitive behavioral therapy (CBT) and mindfulness practices can also be powerful tools for improving focus and emotional regulation. These strategies build structure, enhance self-awareness, improve overall well-being, and help women work on lifestyle interventions, such as sleep, nutrition, and exercise. Additionally, menopause hormone therapy (MHT) can be a game-changer for some women. By stabilizing estrogen levels, MHT may help mitigate the cognitive effects of menopause and support dopamine function, making ADHD symptoms more manageable. When used alongside stimulants, hormone therapy can offer a more comprehensive approach to treatment, addressing both the hormonal and neurological aspects of ADHD. Whether through medication, lifestyle changes, or a combination of treatments, midlife women with ADHD can regain control, optimize their cognitive function, and continue to thrive.Dr. Adrienne Mandelberger, MD is a board-certified gynecologic surgeon and menopause specialist. She is the founder of Balanced Medical, a gynecology and preventative women's health practice on Long Island, NY, and the founder and CEO of the virtual education company All Things Menopause™. Dr. Mandelberger is passionate about educating and empowering women to make informed choices during the menopause transition. Her special interests include the intersection of ADHD and perimenopause.Medical Disclaimer:By listening to this podcast, you agree not to use this podcast as medical advice or to make any lifestyle changes to treat any medical condition in yourself or others. Consult your own physician for any medical issues that you may be having. This entire disclaimer also applies to any of my guests on my podcast.Find Dr. Mandelberger here:Website: https://www.balancedmedicalny.com/IG: @DrMandelberger Educational Program: https://www.all-things-menopause.com/Stay in touch with JFW:Watch on my YouTube channel: https://www.youtube.com/@jillfooswellness/videosFollow me on Instagram: https://www.instagram.com/jillfooswellness/Follow me on Facebook: https://www.facebook.com/jillfooswellnessGrab discounts on my favorite biohacking products: https://www.jillfooswellness.com/health-productsEnjoy 20% savings and free shipping at Fullscript for your favorite supplements by leading brands:https://us.fullscript.com/welcome/jillfooswellnessSubscribe to the JFW newsletter at www.jillfooswellness.com and receive your FREE Guide on How To Increase Your Protein in 5 Easy Steps and your free Protein Powder Recipe Ebook. Schedule your complimentary 30-minute Zoom consultation here:https://calendly.com/jillfooswellness/30-minute-zoom-consultations
The following sermon was chosen as a 'staff-pick' on SermonAudio: Title: Spiritual sedatives and stimulants Subtitle: Alarm call to a sleepy church Speaker: Dr. David P Murray Broadcaster: Stornoway Free Church of Scotland (Cont) Event: Sunday Service Date: 11/10/2002 Bible: Romans 13:11 Length: 48 min.
Previously shared as a paid newsletter in May 2024. In previous newsletters, I've addressed many of the more common contributing factors to brain symptoms, including high pyrroles, copper-zinc imbalances, methylation imbalances, candida overgrowth, mast cell activation, mold and other forms of toxicity, and genetic variants, such as COMT and MAOA.Supplements can be needed to address each of these. Medication can also be necessary when treating mold and mast cell activation.But what happens when someone can't tolerate a supplement or medication because it worsens or creates new brain symptoms? Why, for example, could someone have problems tolerating B6 or SAMe or Methionine. Why might someone have problems with folate, niacinamide, glutathione, certain herbal treatments, antidepressants such as SSRIs, probiotics, antifungal medication or binders such as bentonite clay, activated charcoal, chlorella or cholestyramine?In this newsletter, I'll discuss:* Five common reasons a supplement or medication may worsen symptoms.* Specific supplements and medications that are more likely to do this.* How reactions may point to root causes.* Treatment steps that can improve tolerance.There can be a wide range of brain symptoms that can occur when someone is having an adverse reaction, such as fatigue, brain fog, depression, anxiety, agitation, and even psychosis or mania. I'll use “reactivity” to refer to this range of possibilities. While physical side effects can also occur, the focus here will be on brain symptoms.5 Common Reasons Supplements or Meds May Worsen Symptoms1. Immune ReactivityOur immune system is intertwined with our central nervous system. When our body's immune system reacts to a toxin, microbe, injury, or trauma, we can have inflammatory brain and physical symptoms.“Feel Like I'm Reacting to Everything” - Mast Cell ActivationIf someone is experiencing severe immune reactivity, such as mast cell activation, they may react to many supplements and medications, as well as triggers in their environment and stress. The number of triggers can help point to an exaggerated immune response. In my practice, this high immune reactivity is usually driven by mold toxicity.For many with this obstacle, starting very low and slow can prevent reactions. For others, interventions may be needed to lower immune reactivity and stabilize mast cells. This, however, can require certain supplements. For those who can't tolerate those treatments, limbic system retraining programs help calm the immune system so people can move forward more easily.Sensitivity & IntoleranceIt is possible to have immune sensitivity (or even allergy) to a supplement, though I find this less common. Herbal supplements, for example, which are high in salicylates, may cause symptoms in those with salicylate sensitivity. Certain probiotics have bacterial strains high in histamine. This is an issue for those with histamine intolerance.2. Too Much or Too Little Neurotransmitter ActivitySome people with brain symptoms have high neurotransmitter (NT) activity, and some have low. Common NT's include serotonin (5-HT), dopamine (DA), and norepinephrine (NE). I use the term “neurotransmitter activity” because it's not just about the amount of neurotransmitters present; it's also about the amount of receptors present that pick up NTs and remove them from the space between nerve cells.High Neurotransmitter ActivityToo much neurotransmitter activity can cause brain symptoms such as mania, psychosis, agitation, anxiety, panic, obsessions, compulsions, and hyperactivity. Reactions can occur if supplements or medications are given that further increase NT activity.Examples include:* Overmethylation* Slow COMT (involved in clearing DA and NE) and/or slow MAOA (involved in clearing 5HT, DA and NE)A variant on COMT and/or MAOA doesn't mean they are being expressed.What Increases Neurotransmitters?* SSRIs (Selective Serotonin Reuptake Inhibitor) increase serotonin activity* SNRIs (Serotonin and Norepinephrine Reuptake inhibitors) increase serotonin and norepinephrine activity.* Stimulant medications such as Ritalin and Adderall increase dopamine activity* SAMe and methionine increase serotonin and dopamine activityRemember that there can be times when there is a mixed picture, such as when someone is undermethylated and has a slow COMT.Low Neurotransmitter ActivityReactions can occur if supplements or medication decrease the neurotransmitter activity when it is already low. This could look like depression, apathy, fatigue, and brain fog.Examples include:* Undermethylation* Fast COMT (involved in clearing DA and NE) and/or fast MAOA (involved in clearing 5HT, DA and NE). The NTs are getting cleared too fast.What Decreases Neurotransmitters?* Folate, a nutrient that is good for a lot of people happens to be a big problem for many with psychiatric conditions. Most with underemethylation have low serotonin symptoms (depression and/or anxiety). While folate can help methylation, as an unfortunate aside, it can also further lower serotonin activity. Folate is in most multivitamins and B Complex vitamins. To learn more: Undermethylation, MTHFR & The Great Folate Debate.* Niacinamide can lowers DA and NE.Looking closely at someone's symptoms and traits and assessing methylation through bloodwork can help determine if NTs are too high, low, or mixed and what types of treatment to consider.3. Poor Detoxification or Toxic OverloadZincZinc is one of the most powerful tools I use in my work. Some people can easily tolerate it, while others can struggle. Here are some reasons someone may not tolerate zinc.* High copper—Zinc mobilizes copper. Moving too much copper at once can increase copper symptoms (anxiety, anger, hyperactivity, insomnia).* High toxicity—Zinc is a strong antioxidant. It is needed for the genetic expression of one of the most important antioxidants in our body, metallothionein.It took me 8 months to get my dose up to an optimal range, which is certainly not the norm. I unknowingly had significant mold toxicity at the time.When I start someone on zinc, I slowly build it up over 3-4 weeks. For some (like myself), even this is too fast.GlutathioneThis is the other major antioxidant. If someone is having difficulty tolerating it, they may have problems with detoxification and significant toxicity (metals, biotoxins like mold, and chemicals). These can start to be addressed in several other ways.BindersThese include bentonite clay, chlorella, activated charcoal, and cholestyramine. They bind toxins, especially mold toxins, in the GI tract. If they are started too quickly, the toxins they are supposed to remove get stirred up, which stirs up symptoms. When people say they can't tolerate certain binders, they usually weren't started low enough.There are others, but these are the most common in my experience.4. Underlying Microbial or Microbiome IssueB6B6 is very important for brain health. It is needed for making serotonin, dopamine, and GABA. We use it in all the Walsh nutrient protocols to varying degrees. In the last 10 years, we've seen a decrease in B6 tolerance. It's not clear why. I'm including it in this section because the reactivity is suspected to be related to the microbiome. Perhaps in recent years, we have had collective damage to our microbiomes from toxins and rising EMF exposure. We don't know.The good news is that P5P, the active form of B6, is usually well tolerated. In my practice, I rely heavily on P5P. I will occasionally use it in combination with B6 (if tolerated) for those with especially high pyrroles.Methionine and/or SAMeBoth are used, though usually not together, to help address undermethylation. I suspect candida or mold when someone is having difficulties tolerating either of these. These nutrients are usually better tolerated once candida and/or mold are addressed (or are starting to get addressed).5. Die-OffAnything that kills off microbes, such as candida or mold, can cause a “die off” of those microbes, release toxins, and worsen symptoms. Antifungal supplements, antifungal medication, and probiotics may cause this type of reactivity. Antifungal medications include nystatin, diflucan, itraconazole, and amphotericin B.Herbs and food-based supplements can have antimicrobial effects. Turmeric is one example. There are many others, so it's always worth checking. Worsening symptoms might point to an underlying fungal or other microbial overgrowth. It may also suggest that appropriate binders may be needed first.Addressing or preventing die-offs could mean supporting detoxification, starting binders if necessary, and, again, starting low and going slow.Antidepressants, interestingly, have been shown in labs to have antifungal effects. This does make me wonder if some people who can't tolerate them are having die-off.Root CausesKnowing someone's history of reactions can help point to underlying root causes.As you can see, there are typically ways to help someone tolerate and go on to benefit from a needed supplement or medication.As always, I welcome your thoughts and experience.Until next time,CourtneyP.S. To learn more about non-patient consultations, treatment, and monthly mentorship groups, please visit my website at:CourtneySnyderMD.comMedical Disclaimer:This newsletter is for educational purposes and not intended or implied to be a substitute for professional medical advice, diagnosis or treatment for either yourself or others, including but not limited to patients that you are treating (if you are a practitioner). Consult your own physician for any medical issues that you may be having. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit courtneysnydermd.substack.com/subscribe
America is facing a silent AND growing epidemic: the Adderall crisis. The use of this stimulant (and its generics) has exploded from 35.5 million prescriptions in 2019 to 45 million in 2022. But these numbers only scratch the surface. The DEA warns we're on the brink of our next drug crisis. America is facing a silent AND growing epidemic: the Adderall crisis. The use of this stimulant (and its generics), known by street names like A-Train, Addy, Amps, Christmas Trees, Co-Pilots, Lid Poppers, Smarties, Study Buddies, and Study Skittles has exploded from 35.5 million prescriptions in 2019 to 45 million in 2022. But these numbers only scratch the surface. A dangerous black market has emerged, flooding streets with counterfeit pills indistinguishable from the real thing. Users, often unaware, risk their lives with every dose. Even legitimate prescriptions carry significant dangers. The DEA warns we're on the brink of our next drug crisis. With 5-6 million Americans using Adderall without proper diagnosis and one in four teens in some schools abusing prescription stimulants, we're watching a new generation spiral into un-prescribed/unneeded use and addiction. Thank you to our sponsors: FYSI: Visit https://FYSI.com/DRPHIL or call 800-877-4000 Zecliner: Visit https://Zecliner.com today PureHealth Research: Head over to https://PureHealthResearch.com and save 35% with code PHIL Preserve Gold: Visit: https://drphilgold.com/ Get a FREE precious metals guide that contains essential information on how to help protect your accounts. Text “DRPHIL” to 50505 to claim this exclusive offer from Preserve Gold today.
Association Between Telehealth Initiation Of Stimulant Therapy And New Substance Use Disorder Diagnoses Health Affairs During the COVID-19 pandemic, the Drug Enforcement Administration (DEA) temporarily allowed for prescribing of controlled substances via telehealth and extended the policy through the end of 2025. With concern about potential adverse outcomes with this policy, there is debate about making it permanent. The authors utilized commercial and Medicaid claims data to assess newly diagnosed substance use disorders (SUD) after initiation of stimulants via telehealth versus in-person visits to inform this policy decision. In unadjusted analysis, patients initiated on stimulants via telehealth visits had higher rates of non-ADHD psychiatric comorbidities and new diagnoses of SUD in the year following initiation. In the adjusted analysis, controlling for psychiatric comorbidities, they did not find a difference in SUD outcomes. The authors suggest additional research to inform policy decisions. Read this issue of the ASAM Weekly Subscribe to the ASAM Weekly Visit ASAM
My guest is Dr. John Kruse, M.D., Ph.D., a psychiatrist specializing in treating people with attention-deficit/hyperactivity disorder (ADHD). We discuss the many stimulant and nonstimulant ADHD medications available, covering both their potential benefits and risks. We also explore behavioral approaches to managing ADHD, the key role of maintaining a consistent sleep-wake schedule, and the impact of exercise, fish oil supplementation, and video games on ADHD. Additionally, we examine the genetic and environmental factors contributing to the rise in adult and child ADHD diagnoses and offer various options to consider if you or someone you know is struggling with focus. Read the full episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Joovv: https://joovv.com/huberman LMNT: https://drinklmnt.com/huberman Mateina: https://drinkmateina.com/huberman Timestamps 00:00:00 Dr. John Kruse 00:02:11 Attention-Deficit/Hyperactivity Disorder (ADHD) 00:05:37 Genetics & Environment; COVID Pandemic & ADHD Diagnoses 00:11:43 Sponsors: Eight Sleep & Joovv 00:14:26 ADHD, Interest & Careers 00:20:40 Social Media & Distractibility; ADHD & Lifespan Effect 00:27:39 Hyperfocus, Flow States 00:33:45 Tools: 4 Essential Behaviors for ADHD; Regular Meal Schedule 00:41:06 Sponsor: AG1 00:42:21 Tool: Regular Sleep Timing; Stimulants & Sleep 00:48:06 Insomnia; Tools: Bedtime Structure, Exercise, Phones, Breathing 00:52:30 Nighttime Waking Up; Cyclic Sighing 00:56:35 Exercise; Addiction, Risk, Kids & Stimulants; Catecholamines & Focus 01:04:32 Ritalin, Stimulants, Amphetamines; Amphetamine-Induced Psychosis & Risks 01:16:46 Sponsor: LMNT 01:18:03 Adult ADHD & Medications; Stimulants & Cardiovascular Risk? 01:26:06 Adult ADHD Medication Choices, Psychosis, Cannabis 01:33:49 ADHD Symptoms, Nicotine; Caffeine, Energy Drinks, L-Theanine 01:43:28 Fish Oil, Cardiac Effects & ADHD, Tool: Fish Oil Dose, EPA vs DHA 01:49:38 Sponsor: Mateina 01:51:04 Gut Microbiome 01:52:56 ADHD & Cognitive Behavioral Therapy (CBT), Tool: Task List System 01:57:52 Video Games, Neurofeedback, ADHD Benefit?, Tool: Technology Restriction 02:02:26 Guanfacine, Clonidine, Hypertension, Effects & Timeframe 02:10:13 Modafinil, History & Forms, Dependence 02:19:02 Drug Holidays; Short- vs Long-Acting Drugs, Addiction, Vyvanse 02:28:56 Time Perception, ADHD, Circadian Rhythm Disruption, Phototherapy 02:35:39 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
Caffeine is almost universally seen as an antidote to memory, fatigue, and focus problems, but may affect heart rate and sleep. Sarah Cheyette, M.D., discusses research on caffeine and ADHD, and the risks and benefits of consuming this natural stimulant. ADHD and Caffeine: More Resources Read: 10 Supplements and Vitamins for Brain Health Read: The Truth About Lion's Mane, Psychedelics & Caffeine Read: The Truth About Caffeine and ADHD Access the video and slides for podcast episode #544 here: https://www.additudemag.com/webinar/adhd-and-caffeine-risks-benefits/ Thank you for listening to ADDitude's ADHD Experts podcast. Please consider subscribing to the magazine (additu.de/subscribe) to support our mission of providing ADHD education and support.
Episode HighlightsThe biggest mistakes people make when setting up a sleep sanctuary A reason not to have a TV in the bedroom!Factors to think about when it comes to your sleep environment How to keep your sleep environment for sleep in your mind The substances and chemicals in our sleep environment that can disrupt sleepMattresses are often the highest concentration of toxins in the household and we are exposed to them the entire time we're sleeping How heat and temperature come into play for nervous system shifts in sleepNatural fibers like latex are less likely to develop mold in mattresses than synthetic ones How they use essential oils as a critical part of how the foam behaves in Essentia mattressesWays to address EMFs in the sleep environment and what a pro-athlete study showed Resources We MentionEssentia Mattress - Use code wellnessmama15 for a discountJaspr Air FilterUblockout ShadesNatural fiber pajamas and organic bedsheets LeelaQ
In this episode Mark R. Corkins, MD, FAAP, discusses new recommendations for what children should be drinking. Hosts David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak to Kao-Ping Chua, MD, PhD, about a new study on the use of prescription stimulants by U.S. children between the years 2017 and 2023. For resources go to aap.org/podcast
Added: With Syria's new government cracking down on Captagon, where will production shift in the drug trade's supply chain? Under Bashar al-Assad’s rule, Syria became a hub of Captagon production. With demand continuing, where will the drug market turn to next? In this episode: Niko Vorobyov (@Narco_Polo420), Author of Dopeworld Episode credits: This episode was produced by Marcos Bartolomé, with Amy Walters, Sarí el-Khalili, Melanie Marich, Phillip Lanos, Spencer Cline, and our guest host, Kevin Hirten. It was edited by Noor Wazwaz. Our sound designer is Alex Roldan. Our video editor is Hisham Abu Salah. Alexandra Locke is The Take’s executive producer. Ney Alvarez is Al Jazeera’s head of audio. Connect with us: @AJEPodcasts on Instagram, X, Facebook, Threads and YouTube
Laurent Ruquier et Olivier Bellamy semblent bien s'y connaitre concernant les stimulants sexuels... Retrouvez tous les jours le meilleur des Grosses Têtes en podcast sur RTL.fr et l'application RTL.
Send us a textSarah welcomes Dr. Gabrielle Fundaro to The Beyond Condition Podcast as a new guest for our 5th episode centred around DIET CULTURE.Diet culture loves to sell restrictive plans, elimination diets and supplements disguised as gut health solutions. We are exposed to crash diets that can lead to cranking caffeine intake, mood fluctuations and disturbance of sleep. The list goes on... but we talk the truths.Discussions include:*Identity*Coaching*Body image and relationships*Bodybuilding and competitive sports*Food disorders and relationship with food*Support network*Post show*Injury and life challenges*Stimulant use*Reverse dieting*Therapy and self helpFind Gabrielle on Instagram @trust_and_nourishWatch it here: https://youtu.be/qxXzuS40OvIGet in touch and share this episode @sarahparker_bb
Following up on last week's episode, we are joined once again by Lance Steinberg, M.D. to further discuss the complex issue of medicating children with conditions like ADHD, anxiety, and depression, and if you missed part 1 of the discussion, be sure to go back and listen to that before diving into part 2! In this continuation of our discussion, Dr. Steinberg sheds more light on the approach that is required when considering medication, stressing that a thoughtful evaluation is important before immediately jumping to medical solutions. Dr. Steinberg offers some insights into the FDA-approved medications, why it's important to adhere to age guidelines, and the differences between stimulant options. Dr. Steinberg also explores balancing managing side effects while optimizing benefits, the use of non-stimulant alternatives, and the possibility of off-label treatments for unique situations. The conversation touches on the variety of medication forms available and why it is necessary to customize treatments to each child's needs, taking into account academic, social, and psychological factors. Dr. Steinberg's practical advice on starting with low doses, monitoring progress, and adjusting strategies offers a great perspective on this important part of mental health care for youth. Show Notes: [1:20] - Karen stresses that it's important to take a thorough, holistic approach before considering ADHD medication for children. [2:08] - Dr. Lance Steinberg discusses why understanding FDA age limits and medication safety for ADHD treatment is important. [5:34] - Stimulant medications are generally highly effective for ADHD. [8:32] - Dr. Steinberg advises starting ADHD medication at low doses in order to minimize possible side effects. [11:28] - Regular evaluation is important when managing ADHD treatment via medications. [13:27] - Non-stimulant and off-label medications can also be effective for ADHD, especially with comorbid conditions. [16:16] - Dr. Steinberg discusses the effectiveness and side effects of off-label medications like Modafinil for motivation. [19:03] - Dr. Steinberg talks about structured support for executive functioning. [21:37] - Intervention requires a holistic approach and involves therapists, coaches, and team communication. [24:00] - Dr. Steinberg stresses careful medication management for neurodiverse individuals. [26:04] - He touches upon combining stimulants and non-stimulants for ADHD treatment. [29:18] - Dr. Steinberg warns about the careful combination of SSRIs and stimulants due to potential electrical abnormalities. Links and Related Resources: Episode 105: Medication Helps But is Not a Magic Potion for ADHD with Syed Naqvi, MD Episode 173: Why Treating Symptoms Isn't Enough for Child Wellbeing with Hokehe Eko, MD MPH FAAP Episode 203: ADHD and the Gut-Brain Connection: Exploring Integrative Treatments with Sara Langley, MSN, PMHNP-BC Connect with Us: Get on our Email List Book a Consultation Get Support and Connect with a ChildNEXUS Provider Register for Our Self-Paced Mini Courses: Support for Parents Who Have Children with ADHD, Anxiety, or Dyslexia Connect with Dr. Lance Steinberg: Lance Steinberg, MD's Website Phone: 818-224-3540 Email: steinberg.practice@gmail.com
Expect to hear how to use liquids & Stimulants, Refining Spots, Understanding Fish Behaviour, Liver poweder edges, Understanding bait Movement in the Water, Single Hook Bait edges & Much More... The Carp Cast Patreon FaceBook Mirage Baits
Send Me a Message! In this episode of The Dysregulated Podcast, I take a look at the all-too-familiar "Dexy Blues"—the wave of anxiety and depression that hits when stimulant medications like Vyvanse and dexamphetamine start to wear off. I share my experience with these emotional crashes, how my prescription had to be adjusted to soften the blow, and some quick tips to help avoid those tough afternoons. I also reflect on my friends' experiences, how these medications affect her differently and showing how reactions to even the same drugs can vary from person to person. If you're on ADHD meds, I think you'll really relate to this one!----Follow my journey living with mental illness and the hard-fought lessons learned along the way. Lived experience is the driving force of this podcast, and through this lens, my stories are told. This is a raw, honest, and authentic account of how multiple psychological disorders have shaped my past and continue to influence my future.Support the showTo support the show, CLICK HEREYou can follow me on Instagram: @elliot.t.waters
Our break has ended and for our return Paolo Bandera joins us to take an in depth look at his decades long journey. Sigillum S, Sshe Retina Stimulants, the Sodality and so much more are discussed. Bandera has a great memory and provides a wealth of fascinating insight into his world of sound. Another noise history lesson is in session.
Rabbi Richard Louis Price, M.D. is a Yale & Columbia University-trained psychiatry professor at Weill Cornell Medical College/New York-Presbyterian Hospital. Over the past two decades, he has evaluated over 20,000 patients serving as a medical director at Achieve Behavioral Health in Monsey; Rockland TMS & Wellness Center; Hamaspik of Orange and Rockland Counties; Volunteer Counseling Services in New City; ParCare in Brooklyn, Chai Urgent Care Centers of New York, Pennsylvania, and Florida,, and has a private pediatric and adult psychotherapy and psychopharmacology practice in Monsey, New York. Dr. Price is triple board certified in Psychiatry, Consultation-Liaison/Mind-Body Medicine, and Addiction Medicine and has been awarded numerous patents in the United States, Canada, Europe, and Israel for a novel pharmacotherapy for the treatment of both core and associated symptoms of Autism Spectrum Disorder. Dr. Price has served on the advisory boards and as a national speaker for several pharmaceutical companies, such as Abbvie, Alkermes, Allergan, Almatica, Axsome, Idorsia, Intracellular, Janssen, Jazz, Lumbeck, Neuronetics, Otsuka, Supernus, and Vanda and has been recognized as a top Medical Educator by the American Psychiatric Association. He is also a professional singer and taekwondo black belt. ADHD ARTICLE PUBLISHED: https://pmc.ncbi.nlm.nih.gov/articles/PMC10374479/ HISTORICAL OVERVIEW OF VILOXAZINE: https://pmc.ncbi.nlm.nih.gov/articles/PMC8219567/
Send us a textOpioid makers and distributors are paying over $50 billion to settle lawsuits with states and cities.But how is this settlement money being spent?And is the opioid crisis nearing an end?In this episode of CareTalk, David E. Williams and John Driscoll explore the impacts of recent opioid lawsuits and whether they could finally put an end to the crisis.TOPICS(0:30) Examining the Opioid Settlement(2:50) The Difference Between the Opioid and Tobacco Settlements(4:47) What Are the Settlement Funds Being Used For?(7:09) What's the Impact of the Opioid Settlement?(8:40) What Should States Do With Their Settlement Money?(9:06) The Waves of the Opioid Epidemic(12:50) Combating Waves of Fentanyl and Stimulants(13:53) The Pitfalls in Opioid Addiction Treatment(16:08) Preventing Opioid Addiction(18:27) The Role of Mental Health in Opioid Addiction(20:44) Avoiding Fentanyl With Test Strips
A new study has found stimulant medications and one other drug are the only interventions that reduce ADHD symptoms, although only in the short term. University of Canterbury professor of clinical psychology Julia Rucklidge spoke to Ingrid Hipkiss.
HerbRally | Herbalism | Plant Medicine | Botany | Wildcrafting
Save 50% on ALL COURSES at Heart of Herbs Herbal School! Use coupon code HAPPY50 at checkout before December 31, 2024 LEARN MORE & REGISTER Today's episode is audio from the Heart of Herbs Herbal School Podcast with Demetria Clark. EPISODE DESCRIPTION Ever wondered how ancient herbal practices could transform your modern-day stress and anxiety? Join me, Demetra Clark, on this enlightening journey through the world of herbal nervines, where we unlock the secrets of herbs that calm, invigorate, and nourish your nervous system. We'll delve into the rich history of nervines from ancient Greece to medieval Europe and beyond, and discover how classifications like Relaxants, Stimulants, and Tonics play essential roles in maintaining mental well-being. Get ready to uncover the wonders of valerian, an age-old remedy for sleep and anxiety, as we explore its active constituents, historical significance, and practical uses in everyday life. In our second segment, we bring calming herbal remedies to the forefront, highlighting the benefits and precautions of chamomile, passionflower, and ashwagandha. Learn about chamomile's potential allergic reactions and its interactions with blood thinners, and dive into passionflower's sedative effects on GABA levels for anxiety management. We also explore ashwagandha's adaptogenic properties that reduce stress and enhance cognitive function. With detailed consumption methods and necessary precautions, this episode is your guide to harnessing the power of nature for better mental and physical health. Tune in and let these herbs support your journey to wellness. LEARN MORE ABOUT HEART OF HERBS HERBAL SCHOOL
Reacting to a new study on stimulant addiction full 1784 Mon, 16 Dec 2024 20:49:38 +0000 Hfqlki6gNb3E2mbSqPVlPUQDt3nTjIK5 news,a-newscasts,top picks Marty Griffin news,a-newscasts,top picks Reacting to a new study on stimulant addiction On-demand selections from Marty's show on Newsradio 1020 KDKA , airing weekdays from 10 a.m. to 2 p.m. 2024 © 2021 Audacy, Inc. News News News News news News News News News News False https://player.amperwavepodcasting.com?feed-li
Prevalence of pharmacotherapy for attention-deficit/hyperactivity disorder and prescription stimulant misuse: A national study of US college students Addiction This is an observational study using cross-sectional data from the American College Health Association–National College Health Assessment III. It measured the association between university-level prevalence of attention deficit/hyperactivity disorder (ADHD) medication treatment and prevalence of prescription stimulant misuse (PSM) among college students. Among university students in the United States, there appears to be a positive association between attending universities with a greater prevalence of ADHD medication treatment and risk of prescription stimulant misuse (PSM). This study provides further support for the possibility that ADHD medication treatment prevalence is a risk factor for PSM. Read this issue of the ASAM Weekly Subscribe to the ASAM Weekly Visit ASAM
In this enlightening solo episode of the Jeremy Awakens channel, Jeremy shares five essential tips to naturally manage ADHD in 2025, covering strategies such as starting your day without your phone, consuming healthy fats, avoiding artificial food dyes and sweeteners, staying physically active, and pursuing your passions. By following these methods, you'll be able to improve your focus without resorting to harmful stimulants or medications. Plus, don't miss out on a special bonus tip available through a linked microdosing masterclass.Chapters 00:00 Introduction: Struggling with ADHD?00:52 Challenge Your ADHD: Focus for 10 Minutes01:13 Tip 1: Airplane Mode for the First Hour02:12 Tip 2: Eat Healthy Fats03:10 Tip 3: Eliminate Artificial Additives05:03 Tip 4: Move Your Body05:39 Tip 5: Pursue Your Passions06:46 Recap and Final Thoughts08:10 Bonus Tip: Microdosing08:41 Conclusion: Share and Subscribe**Follow**Jeremy Awakens https://www.instagram.com/jeremy.awakens/Join the Master Mindhttps://www.instagram.com/microdosingmastermind/ Hosted on Acast. See acast.com/privacy for more information.
Watch Here : https://www.youtube.com/watch?v=rRvCCXz-HdI Website: https://vigoroussteve.com/ Consultations: https://vigoroussteve.com/consultations/ eBooks: https://vigoroussteve.com/shop/ YouTube Channel: http://www.youtube.com/user/VigorousSteve/ Workout Clips Channel: https://www.youtube.com/channel/UCWi2zZJwmQ6Mqg92FW2JbiA Instagram: https://instagram.com/vigoroussteve/ TikTok: https://www.tiktok.com/@vigoroussteve Reddit: https://www.reddit.com/r/VigorousSteve/ PodBean: https://vigoroussteve.podbean.com/ Spotify: https://open.spotify.com/show/2wR0XWY00qLq9K7tlvJ000 Patreon: https://www.patreon.com/vigoroussteve
America is facing a silent AND growing epidemic: the Adderall crisis. The use of this stimulant (and its generics) has exploded from 35.5 million prescriptions in 2019 to 45 million in 2022. But these numbers only scratch the surface. The DEA warns we're on the brink of our next drug crisis. America is facing a silent AND growing epidemic: the Adderall crisis. The use of this stimulant (and its generics), known by street names like A-Train, Addy, Amps, Christmas Trees, Co-Pilots, Lid Poppers, Smarties, Study Buddies, and Study Skittles has exploded from 35.5 million prescriptions in 2019 to 45 million in 2022. But these numbers only scratch the surface. A dangerous black market has emerged, flooding streets with counterfeit pills indistinguishable from the real thing. Users, often unaware, risk their lives with every dose. Even legitimate prescriptions carry significant dangers. The DEA warns we're on the brink of our next drug crisis. With 5-6 million Americans using Adderall without proper diagnosis and one in four teens in some schools abusing prescription stimulants, we're watching a new generation spiral into un-prescribed/unneeded use and addiction.
Many growers seeking success for the long term continually look for the best technology, including plant nutrition. Bio-stimulants are a promising frontier for many, and greater scientific understanding of what they can do is helping the process. Distinguished professor Dr. Patrick Brown of UC Davis is one of the world's foremost bio-stimulant experts. He's the chair of this year's Biostimulants World Congress, and said greater understanding of specific biostimulant benefits is crucial to their adoption. He said many bio-stimulant products have been sold with broad statements, which won't be sufficient moving forward. “I think there's an innate recognition and interest amongst farmers that a more biological approach would be useful, and at least a hope, if not yet a belief, that bio-stimulants might be part of that solution,” Brown said.
When you hear Echinacea, chances are you think of its immune-boosting properties. But did you know that this popular use is relatively new? Traditionally, Echinacea was used for entirely different reasons. By rediscovering its original applications, we can break free from the idea that Echinacea is just a “cough, cold and flu” herb and appreciate the many ways it supports the body holistically. In today's episode, you'll learn: What makes Echinacea's flavor so unique and why it creates that signature tingling sensation The best time to use Echinacea when you're feeling sick How Echinacea can be used for venomous snake bites and stings Why Echinacea is considered the quintessential Mars plant in medical astrology Why its combination of cooling and pungent energetics is so rare ———————————— CONNECT WITH SAJAH AND WHITNEY ———————————— To get free in depth mini-courses and videos, visit our blog at: http://www.evolutionaryherbalism.com Get daily inspiration and plant wisdom on our Facebook and Instagram channels: http://www.facebook.com/EvolutionaryHerbalism https://www.instagram.com/evolutionary_herbalism/ Be sure to subscribe to our YouTube Channel: https://www.youtube.com/channel/UCyP63opAmcpIAQg1M9ShNSQ Get a free 5-week course when you buy a copy of the book, Evolutionary Herbalism: https://www.evolutionaryherbalism.com/evolutionary-herbalism-book/ ———————————— ABOUT THE PLANT PATH ———————————— The Plant Path is a window into the world of herbal medicine. With perspectives gleaned from traditional Western herbalism, Ayurveda, Chinese Medicine, Alchemy, Medical Astrology, and traditional cultures from around the world, The Plant Path provides unique insights, skills and strategies for the practice of true holistic herbalism. From clinical to spiritual perspectives, we don't just focus on what herbs are "good for," but rather who they are as intelligent beings, and how we can work with them to heal us physically and consciously evolve. ———————————— ABOUT SAJAH ———————————— Sajah Popham is the author of Evolutionary Herbalism and the founder of the School of Evolutionary Herbalism, where he trains herbalists in a holistic system of plant medicine that encompasses clinical Western herbalism, medical astrology, Ayurveda, and spagyric alchemy. His mission is to develop a comprehensive approach that balances the science and spirituality of plant medicine, focusing on using plants to heal and rejuvenate the body, clarify the mind, open the heart, and support the development of the soul. This is only achieved through understanding and working with the chemical, energetic, and spiritual properties of the plants. His teachings embody a heartfelt respect, honor and reverence for the vast intelligence of plants in a way that empowers us to look deeper into the nature of our medicines and ourselves. He lives on a homestead in the foothills of Mt. Baker Washington with his wife Whitney where he teaches, consults clients, and prepares spagyric herbal medicines. ———————————— WANT TO FEATURE US ON YOUR PODCAST? ———————————— If you'd like to interview Sajah or Whitney to be on your podcast, click here to fill out an interview request form.
“Behind the Evidence” is the addiction medicine podcast of the Grayken Center for Addiction at Boston Medical Center, and a project of the Center's free bimonthly newsletter Alcohol, Other Drugs, and Health: Current Evidence (AODH). This episode was recorded 24 June 2024 and features an interview with Ayesha Appa, MD on her recent publication in Drug and Alcohol Dependence: “Stimulant use and opioid-related harm in patients on long-term opioids for chronic pain.” Click here to read AODH's summary of Dr Appa's article. Hosts: Honora L. Englander, MD and Marc R. Larochelle, MDProduction: Raquel Silveira, MBAEditing: Casy Calver, PhDMusic and cover art: Mary Tomanovich, MAMiriam Komaromy, MD is the Medical Director of the Grayken Center for Addiction, and co-Editor-in-Chief of AODH, together with David Fiellin, MDLearn more about AODH and subscribe for free at www.aodhealth.org“Behind the Evidence” is supported by the Grayken Center for Addiction at Boston Medical Center. It is intended for educational purposes only, and should not be considered medical advice. The views expressed here are our own, and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities.
Our friend Cee Mo has two new singles that have dropped! Check out "Stimulants", and "Get Free" on any music streaming platform by Cee Mo and the Lovers!
In this powerful episode, Kelley sits down with Vince Pitstick, a trailblazer in functional and holistic health coaching. Vince's journey from personal trainer to pioneer in functional health has helped countless individuals reclaim their well-being, especially those struggling with hormonal imbalances and weight loss resistance.In this conversation, Vince dives deep into the complexities of women's hormones and how they intersect with metabolism, weight loss, and disease. If you've ever felt stuck in your health journey—whether due to unexplained weight gain, hormonal fluctuations, or resistance to traditional weight loss methods—this episode is for you.Vince shares his groundbreaking insights on root cause medicine and his innovative 4F Process, which is designed to restore balance and unlock your body's potential for optimal health. You'll also learn about the correlation between metabolic rate and disease, how to reverse weight loss resistance, and the debate surrounding GLP-1 agonists.Vince goes even deeper into why he believes all disease is rooted in metabolic dysfunction and how balancing hormones can unlock sustainable weight loss. His fresh perspective on aging and metabolism, plus a surprising approach to breaking through weight loss plateaus, will leave you feeling empowered and ready to take control of your health.This episode is packed with actionable insights and breakthrough strategies for anyone struggling with hormonal health or weight loss resistance. You don't want to miss it! Tune in to hear Vince's wisdom on how to transform your health from the inside out.What You'll Learn:How rare health conditions in childhood led Vince to functional healthThe fundamentals of root cause medicine and why it mattersThe link between women's hormones, weight loss, and metabolic healthSurprising trends in metabolic rate and their connection to diseaseHow to reverse weight loss resistance naturallyThe GLP-1 agonist debate and its implications for weight lossWhy adrenaline and stress could be fueling your weight gainA groundbreaking approach to hormonal health and long-term weight managementIf you're ready to break free from weight loss resistance and balance your hormones once and for all, this episode is your guide!
In this conversation, Liz Rohr and Shelby Pope discuss the importance of taking a comprehensive history of substance use, and how to assess and treat stimulant use disorder. They cover the challenges healthcare providers face in asking the right questions, and emphasize the need for open conversations and non-judgmental approaches.They cover screening for addiction, how to elicit a substance use history, including types and routes of substance use. Shelby covers the mechanism of action of cocaine and methamphetamine in the brain, the withdrawal symptoms associated with stimulant use disorder, and the next steps for primary care providers in managing patients with stimulant use disorder. They also explore the use of psychosocial interventions and off-label pharmacologic treatments for stimulant use disorder.TakeawaysOpen and non-judgmental conversations are essential when discussing substance use with patients.Screening practices, such as using screeners like PHQ-2, SBIRT, and DAST, can help identify substance misuse or struggles.Taking a comprehensive history of substance use, including the type, amount, frequency, and motivation, is crucial for providing appropriate care.Healthcare providers should be aware of the different routes of administration and the potential risks associated with each.Stimulant use disorder, particularly cocaine and methamphetamine use, can have significant adverse effects and poor outcomes. Cocaine and methamphetamine are both monoamine neurotransmitter reuptake inhibitors, increasing serotonin, norepinephrine, and dopamine levels in the brain.There is a withdrawal syndrome associated with stimulant use disorder, characterized by depression, fatigue, and sleep disturbances.In managing patients with stimulant use disorder, primary care providers should consider triage based on severity and acuity, and refer patients to appropriate resources such as rehab or the ER.Psychosocial interventions, such as cognitive behavioral therapy and contingency management, are the mainstay of treatment for stimulant use disorder.Off-label pharmacologic treatments for stimulant use disorder include mirtazapine, bupropion, injectable naltrexone, topiramate, and psychostimulants.It is important for healthcare providers to be aware of state regulations and their own comfort level in prescribing off-label medications for stimulant use disorder.For a full transcript and conversation chapters, visit the blog: https://www.realworldnp.com/blog/treating-substance-use-disorder ______________________________© 2024 Real World NP. For educational and informational purposes only, see realworldnp.com/disclaimer for full details. Hosted on Acast. See acast.com/privacy for more information.