Podcast appearances and mentions of Robin Warren

Today in 1951, the birth of Barry Marshall, a Nobel Prize winning doctor who, while working with colleague Robin Warren, proved what was behind most ulcers by giving himself an ulcer. Plus: an 11 year old in England saves an engraving from the dumpster that turns out to be pretty important. The Doctor Who Drank Infectious Broth, Gave Himself an Ulcer, and Solved a Medical Mystery (Discover Magazine) Dürer Engraving Found by 11-Year-Old in Dumpster Sells for $44,000 (Hyperallergic) Keep this podcast healthy as a backer on Patreon --- Support this podcast: https://podcasters.spotify.com/pod/show/coolweirdawesome/support

This is a recap of the top 10 posts on Hacker News on August 2nd, 2024.This podcast was generated by wondercraft.ai(00:33): The upstream cause of the youth mental health crisis is the loss of communityOriginal post: https://news.ycombinator.com/item?id=41139149&utm_source=wondercraft_ai(02:07): Hackberry-Pi_Zero – A handheld Linux terminal using Raspberry Pi Zero 2WOriginal post: https://news.ycombinator.com/item?id=41138701&utm_source=wondercraft_ai(03:17): The Marshmallow Test does not reliably predict adult functioningOriginal post: https://news.ycombinator.com/item?id=41139854&utm_source=wondercraft_ai(04:26): Sqlite-vec: Work-in-progress vector search SQLite extension that runs anywhereOriginal post: https://news.ycombinator.com/item?id=41137658&utm_source=wondercraft_ai(05:38): Null-Restricted and Nullable TypesOriginal post: https://news.ycombinator.com/item?id=41136974&utm_source=wondercraft_ai(06:57): Tauri 2.0 Release CandidateOriginal post: https://news.ycombinator.com/item?id=41141962&utm_source=wondercraft_ai(08:08): Robin Warren, pathologist who rewrote the science on ulcers, has diedOriginal post: https://news.ycombinator.com/item?id=41137694&utm_source=wondercraft_ai(09:22): What happens in a mind that can't 'see' mental imagesOriginal post: https://news.ycombinator.com/item?id=41138338&utm_source=wondercraft_ai(10:35): About Google Chrome's "This extension may soon no longer be supported"Original post: https://news.ycombinator.com/item?id=41140185&utm_source=wondercraft_ai(11:46): ArchiveTeam WarriorOriginal post: https://news.ycombinator.com/item?id=41141349&utm_source=wondercraft_aiThis is a third-party project, independent from HN and YC. Text and audio generated using AI, by wondercraft.ai. Create your own studio quality podcast with text as the only input in seconds at app.wondercraft.ai. Issues or feedback? We'd love to hear from you: team@wondercraft.ai

Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Stomach Ulcers and Dental Cavities, published by Metacelsus on August 6, 2023 on LessWrong. (This is a linkpost from my blog, De Novo) Recently I learned about an effort to prevent dental cavities by using genetically modified bacteria to outcompete cavity-causing bacteria. This got me thinking: why has the idea of preventing cavities by targeting bacteria not been more developed already? The current situation reminds me of the history of stomach ulcers. Before the 1980s, doctors recommended avoiding spicy foods and reducing stress to alleviate stomach ulcers. However, once Robin Warren and Barry Marshall proved ulcers were due to H. pylori infection, treatment with antibiotics to eliminate the bacteria became the standard of treatment. Today, dentists recommend avoiding sugary foods and brushing your teeth to prevent cavities. But we know cavities are caused by bacteria (in particular Streptococcus mutans), so why not directly attack cavity-causing bacteria? Some potential ideas: Selectively targeted antibiotics Vaccines (previously tried in the 1980s, not very successful because it's difficult to get antibodies to penetrate biofilms, and also because S. mutans has several different strains with different antigenic profiles) Outcompeting S. mutans with different bacteria (the current effort by Aaron Silverbook, which I think is promising) Basically, what Aaron Silverbook is proposing to do is recreate a strain of S. mutans, termed BSC3-L1, that is deficient in lactic acid production. This was previously developed by a company called Oragenics, but they abandoned the effort (I think due to financial reasons). It seems Aaron's team is mostly people from software backgrounds, so they would probably appreciate help from any talented microbiologists who happen to be reading this post. In a famous case of self-experimentation, Marshall drank a culture of H. pylori and subsequently developed gastritis. For this work, Warren and Marshall earned the 2005 Nobel in Physiology/Medicine. Thanks for listening. To help us out with The Nonlinear Library or to learn more, please visit nonlinear.org

Link to original articleWelcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Stomach Ulcers and Dental Cavities, published by Metacelsus on August 6, 2023 on LessWrong.(This is a linkpost from my blog, De Novo)Recently I learned about an effort to prevent dental cavities by using genetically modified bacteria to outcompete cavity-causing bacteria. This got me thinking: why has the idea of preventing cavities by targeting bacteria not been more developed already?The current situation reminds me of the history of stomach ulcers. Before the 1980s, doctors recommended avoiding spicy foods and reducing stress to alleviate stomach ulcers. However, once Robin Warren and Barry Marshall proved ulcers were due to H. pylori infection, treatment with antibiotics to eliminate the bacteria became the standard of treatment.Today, dentists recommend avoiding sugary foods and brushing your teeth to prevent cavities. But we know cavities are caused by bacteria (in particular Streptococcus mutans), so why not directly attack cavity-causing bacteria?Some potential ideas:Selectively targeted antibioticsVaccines (previously tried in the 1980s, not very successful because it's difficult to get antibodies to penetrate biofilms, and also because S. mutans has several different strains with different antigenic profiles)Outcompeting S. mutans with different bacteria (the current effort by Aaron Silverbook, which I think is promising)Basically, what Aaron Silverbook is proposing to do is recreate a strain of S. mutans, termed BSC3-L1, that is deficient in lactic acid production. This was previously developed by a company called Oragenics, but they abandoned the effort (I think due to financial reasons). It seems Aaron's team is mostly people from software backgrounds, so they would probably appreciate help from any talented microbiologists who happen to be reading this post.In a famous case of self-experimentation, Marshall drank a culture of H. pylori and subsequently developed gastritis. For this work, Warren and Marshall earned the 2005 Nobel in Physiology/Medicine.Thanks for listening. To help us out with The Nonlinear Library or to learn more, please visit nonlinear.org

Link to original articleWelcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Stomach Ulcers and Dental Cavities, published by Metacelsus on August 6, 2023 on LessWrong. (This is a linkpost from my blog, De Novo) Recently I learned about an effort to prevent dental cavities by using genetically modified bacteria to outcompete cavity-causing bacteria. This got me thinking: why has the idea of preventing cavities by targeting bacteria not been more developed already? The current situation reminds me of the history of stomach ulcers. Before the 1980s, doctors recommended avoiding spicy foods and reducing stress to alleviate stomach ulcers. However, once Robin Warren and Barry Marshall proved ulcers were due to H. pylori infection, treatment with antibiotics to eliminate the bacteria became the standard of treatment. Today, dentists recommend avoiding sugary foods and brushing your teeth to prevent cavities. But we know cavities are caused by bacteria (in particular Streptococcus mutans), so why not directly attack cavity-causing bacteria? Some potential ideas: Selectively targeted antibiotics Vaccines (previously tried in the 1980s, not very successful because it's difficult to get antibodies to penetrate biofilms, and also because S. mutans has several different strains with different antigenic profiles) Outcompeting S. mutans with different bacteria (the current effort by Aaron Silverbook, which I think is promising) Basically, what Aaron Silverbook is proposing to do is recreate a strain of S. mutans, termed BSC3-L1, that is deficient in lactic acid production. This was previously developed by a company called Oragenics, but they abandoned the effort (I think due to financial reasons). It seems Aaron's team is mostly people from software backgrounds, so they would probably appreciate help from any talented microbiologists who happen to be reading this post. In a famous case of self-experimentation, Marshall drank a culture of H. pylori and subsequently developed gastritis. For this work, Warren and Marshall earned the 2005 Nobel in Physiology/Medicine. Thanks for listening. To help us out with The Nonlinear Library or to learn more, please visit nonlinear.org

Scaling DevTools is the podcast that investigates how DevTools go from zero to one. Created by Jack Bridger, founder of BitReach. BitReach helps DevTool companies reach more developers. In scaling DevTools, Jack explores how startups sell to developers, build tools and become successful.What we cover The early days of Corrello The advantages of marketplaces Where to hear from Robin Robin's Twitter Robin's Mastadon Corrello Blue Cat Reports  Where to hear from us Jack's Twitter  Scaling DevTools Twitter Scaling DevTools YouTube Scaling DevTools Blog Scaling DevTools newsletter 

We have two guests interviewing each other! I invited two friends of the podcast, Andy Brice, and Robin Warren, to chat with each other about what it's like running a lifestyle business in 2022 compared to, say, 10 years ago. Although both Andy and Robin run what they call lifestyle businesses, they've taken different approaches, based on what they want to get out of their business.Mentioned in this episode:Robin's company: bluecatreports.comAndy's products: Easy Data Transform, PerfectTablePlan, Hyper PlanAndy on Twitter: @successfulswAndy's blog: Successful SoftwareRobin on Twitter: @robinwarren  

Three-time guest Robin Warren, founder of Corrello, achieves "very infrequent guest co-host" status. We chat about a number of aspects of mental wellbeing for bootstrappers - getting out of the house, taking breaks, dealing with boredom, and making your business less dependent on you.Show links:Robin on TwitterBlue Cat Reports websiteBlue Cat Reports on Trello 

Episode 64: H. pylori. Dr Lorenzo explains testing, diagnosis, and treatments for H. pylori, a bacterium that can cause peptic ulcer disease and other complications.By Anabell Lorenzo, MD, and Hector Arreaza, MD.   This is Rio Bravo qWeek, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California. Our program is affiliated with UCLA, and it's sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. Today we are going to discuss a topic that may be very basic for many of our listeners, but it is important to check our knowledge foundation to keep building on it. Helicobacter pylori was discovered in 1982 by Barry Marshall and Robin Warren from Australia. They received the Nobel prize in 2005 for their discovery of “the bacterium Helicobacter pylori and its role in gastritis and peptic ulcer disease”. 1. What is H. pylori?It's a gram-negative bacteria found in the stomach causing infection and GI symptoms such as dyspepsia. It is a chronic infection and it's usually acquired in childhood. Incidence and prevalence of H. pylori infection are generally higher in people born outside of North America than among people born here. About 50% of humans are infected by H. pylori in the world. The infection can be life-long and cause no symptoms. The infection can cause peptic ulcers too. 2. When do you test for H. pylori and treat it?Test these patients for H. pylori: -All patients with active peptic ulcer disease (PUD).-Patients with history of PUD (unless previous cure of H. pylori infection has been documented).-Patients diagnosed with low-grade gastric mucosa-associated lymphoid tissue (MALT) lymphoma.-Patients with a history of endoscopic resection of early gastric cancer (EGC).In a few words, test patients with PUD and stomach malignancies.  Controversial indications include:- Consider non-endoscopic test (stool or breath) in patients with unexplained dyspepsia who are younger than 60 years old without red flags.- Patients with typical symptoms of gastroesophageal reflux disease (GERD) who do not have a history of PUD do not need to be tested for H. pylori infection. However, for those who are tested and found to be infected, treatment should be offered, but to the patient that the effects of treatment of H. pylori on GERD symptoms are unpredictable. This means that eradication of H. pylori may or may not affect GERD symptoms. -Patients taking long-term, low-dose aspirin (to reduce the risk of ulcer bleeding)-Prior to initiation of chronic treatment with NSAIDs-Patients with unexplained iron deficiency anemia despite an appropriate evaluation  3. What are the testing options for H. pylori?-In patients is having an EGD, they can be tested with gastric biopsy histology and biopsy urease (best options). Endoscopy biopsy is the best diagnostic test for H. pylori. -In patients who do not require EGD, NONINVASIVE TESTING like STOOL ANTIGEN ASSAY and UREA BREATH TEST are a great option-Before performing the test, it is important to stop PPIs (proton pump inhibitors) for 2-4 weeks and Bismuth/antibiotics use within 4 weeks to avoid false negative results.  4. What ar ethe recommended first-line treatments for H. pylori?Triple therapy: Clarithromycin triple therapy is the recommended option. This treatment includes PPI, clarithromycin, and amoxicillin OR metronidazole for 14 days. This is the recommended in areas where clarithromycin resistance is less than 15%, and in patients with no exposure to macrolides. The two antibiotics and PPI twice a day are given for 2 weeks, and the PPI is continued once daily for one month. PPI may be omeprazole, pantoprazole, or others. Quadruple therapy: Bismuth quadruple therapy consisting of a PPI, bismuth, tetracycline, and a nitro imidazole for 10–14 days is another treatment option. Bismuth quadruple therapy is particularly attractive in patients with any previous macrolide exposure or who are allergic to penicillin. 5. Should we test for H. pylori eradication?Confirmation of eradication should be performed in all patients treated for H. pylori because of increasing antibiotic resistance. There is not a lot of information about antibiotic resistance in the US. The test should be done 4 weeks after completing treatment. 6. What is refractory H. pylori infection? Refractory H. pylori infection is defined by a persistent positive H. pylori test (no serologic), at least 4 weeks after 1 or more full course(s) of a recommended first-line therapy, and when the patient has been off any medications, such as proton-pump inhibitors (PPIs), that may impact the test sensitivity. Refractory H. pylori infection should be differentiated from recurrent infection. A recurrent infection happens when a no serologic test was negative after treatment, then becomes positive again. 7. What tests can be done to evaluate H. pylori antibiotic resistance?We can test for resistance with culture or molecular testing, but these tests are currently not widely available in US. 8. What are the option for salvage therapy after failure of treatment? In patients with persistent H. pylori infection, try to avoid antibiotics that have been previously taken by the patient. Bismuth quadruple therapy or levofloxacin salvage regimens are the preferred treatment options if a patient received a first-line treatment containing clarithromycin.  Regimens that contain clarithromycin or levofloxacin are the preferred treatment options if a patient received bismuth quadruple therapy.  Rifabutin triple regimen consisting of a PPI, amoxicillin, and rifabutin for 10 days is a suggested salvage regimen. Conclusion:H. pylori is an infection that can be asymptomatic, but it needs to be eradicated if symptoms are present. Detection of H. pylori is fairly easy, but we may need to perform an EGD if patient has red flags. Antibiotics and PPIs are the first line of treatment. Test of cure is recommended for all patients. ____________________________Now we conclude our episode number 64 “H. pylori.” Dr Lorenzo explained when and how to test patients for H. pylori. She explained that patients with GERD symptoms to not need to be tested for H. pylori, but if they are tested and have positive results, then we should eradicate H. pylori. Remember to stop PPIs 2-4 weeks before non-endoscopic tests for H. pylori. Even without trying, every night you go to bed being a little wiser.Thanks for listening to Rio Bravo qWeek. If you have any feedback about this podcast, contact us by email RBresidency@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. This podcast was created with educational purposes only. Visit your primary care physician for additional medical advice. This week we thank Hector Arreaza and Anabell Lorenzo. Audio edition: Suraj Amrutia. See you next week! _____________________References:William D. Chey, Grigorios I. Leontiadis, Colin W. Howden, and Steven F. Moss. ACG Clinical Guideline: Treatment of Helicobacter pylori Infection. Am J Gastroenterol 2017; 112:212–238. https://pubmed.ncbi.nlm.nih.gov/28071659/ Shailja C. Shah, Prasad G. Iyer, and Steven F. Moss. AGA Clinical Practice Update on the Management of Refractory Helicobacter pylori Infection: Expert Review. Gastroenterology 2021;160:1831–1841. https://pubmed.ncbi.nlm.nih.gov/33524402/ J. Thomas Lamont. Treatment regimens for Helicobacter pylori in adults. Up to date, last updated on May, 20, 2021. https://www.uptodate.com/contents/treatment-regimens-for-helicobacter-pylori-in-adults?search=h%20pylori%20treatment&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1. 

Xin chào các bạn, hôm nay là ngày 11 tháng 6 và hôm nay là ngày gì? SỰ KIỆN 1935 - Nhà phát minh Edwin Armstrong trình diễn công khai đầu tiên về việc phát sóng FM ở Hoa Kỳ tại Alpine, New Jersey . 2008 - Kính viễn vọng không gian tia Gamma Fermi được phóng lên quỹ đạo. 2009 – Manchester United chấp nhận bỏ ra 80 triệu bảng để được mua Cristiano Ronaldo từ Real Madrid 2010 - World Cup lần đầu tiên tổ chức tại châu Phi do Nam Phi đăng cai 2018 - 3 World Trade Center chính thức khai trương. Đây là một tòa nhà chọc trời được xây dựng lại từ tòa nhà World Trade Center cũ bị sụp đổ trong sự kiện 11/9 ở Lower Manhattan. Sinh 1894 - Kiichiro Toyoda, doanh nhân Nhật Bản, là con trai của người sáng lập Toyoda Loom Works - Toyoda Sakichi. Toyoda Kiichiro là người đã đưa quyết định chuyển Toyoda Loom Works sang lĩnh vực sản xuất xe hơi, được coi như là một doanh nhân mạo hiểm ở đúng thời điểm. 1899 - Yasunari Kawabata , tiểu thuyết gia và nhà văn. Ông là tiểu thuyết gia người Nhật đầu tiên và người châu Á thứ ba, sau Rabindranath Tagore (Ấn Độ năm 1913) và Shmuel Yosef Agnon (Israel năm 1966), đoạt Giải Nobel Văn học 1937 - Robin Warren , là nhà nghiên cứu bệnh học người Úc, người đoạt giải Nobel và người được công nhận là người có công trong việc phát hiện lại vi khuẩn Helicobacter pylori hay còn gọi là vi khuẩn HP năm 1979, cùng với Barry Marshall. Mất 1341 – Trần Hiến Tông, hoàng đế thứ sáu của nhà Trần (s. 1319). 1937 - RJ Mitchell , kỹ sư người Anh, người thiết kế dòng thủy phi cơ Supermarine Spitfire (sinh năm 1895) 2008 - Võ Văn Kiệt , tên thật Phan Văn Hòa, bí danh Sáu Dân, là nhà chính trị Việt Nam. Ông làm Thủ tướng Chính phủ thứ tư (trước kia là Chủ tịch Hội đồng Bộ trưởng) của nước Cộng hòa Xã hội Chủ nghĩa Việt Nam từ 8/8/1991 đến 25/9/1997. Ông được nhiều báo chí đánh giá là người đã đẩy mạnh công cuộc Đổi Mới và cải cách chính sách ở Việt Nam kể từ năm 1986, là "tổng công trình sư" nhiều dự án táo bạo của thời kỳ Đổi Mới. 1784 – Lê Quý Đôn, là vị quan thời Lê trung hưng, cũng là nhà thơ và được mệnh danh là "nhà bác học lớn của Việt Nam trong thời phong kiến". #aweektv #ngay11thang6 #vovankiet #lequydon #homnayngaygi #todayinhistory --- Send in a voice message: https://anchor.fm/aweek-tv/message

Summary How to validate SaaS ideas without access to any specific market? By iterating fast and finding an audience through first prototypes. Robin Warren is running a successful suite of Trello integrations for teams and shares his story of gaining early traction without having an audience or market insights. Episode Victor 00:04 Welcome to Product […]

Professor Barry Marshall is a physician and 2005 Nobel Laureate in physiology and medicine. Awarded for his, and fellow colleague Dr Warren Robin's discovery of the Helicobacter Pylori bacteria and it's causative relationship with gastritis and peptic ulcers.Barry James Marshall AC FRACP FRS FAA[1][2] (born 30 September 1951) is an Australian physician, Nobel Prize Laureate in Physiology or Medicine, and Professor of Clinical Microbiology at the University of Western Australia. Marshall and Robin Warren showed that the bacterium Helicobacter pylori (H. pylori) plays a major role in causing many peptic ulcers, challenging decades of medical doctrine holding that ulcers were caused primarily by stress, spicy foods, and too much acid. This discovery has allowed for a breakthrough in understanding a causative link between Helicobacter pylori infection and stomach cancer.Find Barry here http://barryjmarshall.blogspot.com/https://twitter.com/barjammarhttps://www.nobelprize.org/prizes/medicine/2005/marshall/lecture/Support the show (https://www.patreon.com/labanditchburn?fan_landing=true)

This episode covers the 2005 Nobel Prize in Physiology or Medicine, which was awarded to Barry J. Marshall and J. Robin Warren. The Nobel Assembly at the Karolinska Institute chose to give Marshall and Warren the prize “for their discovery of the bacterium Helicobacter pylori and its role in gastritis and peptic ulcer disease”. Topics include the symptoms associated with gastritis and peptic ulcer disease, Marshall deliberately infecting himself with the bacterium, and current treatments for H. pylori infections. 

In this week's episode of The Adelaide Show, we are rustling through our present cupboard and serving up some audio treats to see you through the festive period. To kick things off for our audio Christmas stocking, in the SA Drink Of The Week, we chat with Australia's most trusted Sparkling Winemakers, Trina Smith, who has just launched a stunning, SA-based premium vintage sparkling wine, Jacob. Then we have three goodies. Firstly, Charles Firth joins us. Charles is a founder of The Chaser - that hilarious comedy team that breathed new life into satire and political comedy on the ABC and now is responsible for The Chaser Report which is not only a podcast but also one of Australia's top ten news sites, according to recent surveys. This interview was recorded for the School Of Hard Knock Knocks podcast but Steve kept some parts for us, especially a roasting dished out to South Australian Chaser writer, John Delmenico! Secondly, we interview Nobel Laureate, Professor Barry Marshall, who won the Nobel Prize for his work discovering that ulcers were not caused by acid but rather they were due to bacteria. This interview was originally recorded for the This Pathological Life podcast but because Professor Marshall achieved his breakthrough working with South Australian pathologist, Dr Robin Warren, Steve wanted to share the SA flavour with us. Thirdly, Steve recorded a chat with Ian McFadyen earlier this year, the man who brought us the Comedy Company. Again, this was recorded for the School Of Hard Knock Knocks podcast but there are two important aspects Steve wanted to share. Firstly, how the generosity of helping someone out actually led to the Comedy Company being possible, and secondly, how happenstance has continued to follow Ian, including some South Australian connections. And finally, in the Musical Pilgrimage, Professor Flint has chipped in with some goodies of his own, a new album of his iconic dinosaur songs produced in Acoustic Unplugged style. You can navigate episodes using chapter markers in your podcast app. Not a fan of wine? You can click next to jump to the next chapter in the show. We're here to serve! And please consider becoming part of our podcast by joining our Inner Circle. It's an email list. Join it and you might get an email on a Sunday or Monday seeking questicon ideas, guest ideas and requests for other bits of feedback about YOUR podcast, The Adelaide Show. Email us directly and we'll add you to the list: podcast@theadelaideshow.com.au If you enjoy the show, please leave us a 5-star review in iTunes or other podcast sites, or buy some great merch from our Red Bubble store - The Adelaide Show Shop. We'd greatly appreciate it. And please talk about us and share our episodes on social media, it really helps build our community. Oh, and here's our index of all episode in one concise page   Running Sheet: The 2020 Adelaide Show Podcast Audio Christmas Stocking00:00:00 Intro Introduction to the show. 00:05:31 SA Drink Of The Week The SA Drink Of The Week is Jacob, a vintage South Australian sparkling wine and we taste it with winemaker, Trina Smith. 00:18:40 Charles Firth Charles Firth is a founder of The Chaser - that hilarious comedy team that breathed new life into satire and political comedy on the ABC and now is responsible for The Chaser Report which is not only a podcast but also one of Australia's top ten news sites, according to recent surveys. This interview was recorded for the School Of Hard Knock Knocks podcast but Steve kept some parts for us, especially a roasting dished out to South Australian Chaser writer, John Delmenico! And just in time for Christmas, you can buy The Chaser Annual, which is hilarious! 00:54:15 Professor Barry Marshall Professor Barry Marshall AC FRACP FRS FAA is an Australian physician, Nobel Prize Laureate in Physiology or Medicine, and Professor of Clinical Microbiology at the University of Western Australia. He won the Nobel Prize for his work discovering that ulcers were not caused by acid but rather they were due to bacteria. This interview was originally recorded for the This Pathological Life podcast but because Professor Marshall achieved his breakthrough working with South Australian pathologist, Dr Robin Warren, Steve wanted to share the SA flavour with us. Steve produces the pathology podcast for Clinpath Pathology with Dr Travis Brown, who you hear in the interview but Steve forgot to credit until the end of the show. Whoops! 01:24:46 Ian McFadyen Ian McFadyen is the man who created The Comedy Company - a comedy icon on Australian TV in the late 80s and early 90s. He's had a broad career but in this interview originally recorded by Steve for the School Of Hard Knock Knocks podcast there are two important aspects we wanted to share. Firstly, how the generosity of helping someone out actually led to the Comedy Company being possible, and secondly, how happenstance has continued to follow Ian, including some South Australian connections. 01:58:23 Musical Pilgrimage In the musical pilgrimage, we have a song from Professor Flint's new album, Paleo Jam, called Rocks And Bones. You can listen to and download the album from Professor Flint's Bandcamp page. Support the show: https://theadelaideshow.com.au/listen-or-download-the-podcast/adelaide-in-crowd/ See omnystudio.com/listener for privacy information.

** Thanks for downloading this episode. If you'd like to stay in touch with our continuing story, Season 2 continues at This Medical Life, in which Dr Travis Brown continues his exploration of diseases and our approaches to treatment from history to the modern day. Have a look in your podcast app now for This Medical Life, and hit subscribe so you never miss an episode ** In 1983, Dr Robin Warren and Dr Barry Marshall embarked upon a study to investigate the significance of bacterial found in the stomachs of ulcer patients. This journey would take them over a decade to complete and was riddled with self-doubt, persistent scepticism, and challenging centuries of medical dogma but their persistence ultimately led to the highest accolade in Medicine. Oh, and a bout of bad breath.Helicobacter pylori is a gram-negative bacteria that has evolved with humans. With an estimated worldwide prevalence of up to 50%, this organism has found a survival niche where it is perfectly suited to thrive in the stomach's highly acidic environment. Unfortunately for those of us who have it, it will cause inflammation (gastritis) but can eventually lead to cancer (gastric adenocarcinoma).Our interview is with Professor Barry Marshall who navigates the lows of persistent knockbacks through to the worldwide tour that lead to the Nobel Prize in 2005. Professor Barry MarshallNobel Prize Laureate and Professor of Clinical Microbiology The discovery by Dr Warren and Professor Marshall has benefited millions of people, maybe saving a million lives over the last 10 or 20 years. Barry James Marshall AC FRACP FRS FAA is an Australian physician, Nobel Prize Laureate in Physiology or Medicine, and Professor of Clinical Microbiology at the University of Western Australia. https://www.uwa.edu.au/profile/barry-marshall Additional links of interest: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(05)67587-3/fulltext  https://www.science.org.au/learning/general-audience/history/interviews-australian-scientists/professor-barry-marshall/teacher See omnystudio.com/listener for privacy information.

In 1983, Dr Robin Warren and Dr Barry Marshall embarked upon a study to investigate the significance of bacterial found in the stomachs of ulcer patients. This journey would take them over a decade to complete and was riddled with self-doubt, persistent scepticism, and challenging centuries of medical dogma but their persistence ultimately led to the highest accolade in Medicine. Oh, and a bout of bad breath. Helicobacter pylori is a gram-negative bacteria that has evolved with humans. With an estimated worldwide prevalence of up to 50%, this organism has found a survival niche where it is perfectly suited to thrive in the stomach's highly acidic environment. Unfortunately for those of us who have it, it will cause inflammation (gastritis) but can eventually lead to cancer (gastric adenocarcinoma). Our interview is with Professor Barry Marshall who navigates the lows of persistent knockbacks through to the worldwide tour that lead to the Nobel Prize in 2005. Professor Barry Marshall Nobel Prize Laureate and Professor of Clinical Microbiology The discovery by Dr Warren and Professor Marshall has benefited millions of people, maybe saving a million lives over the last 10 or 20 years. Barry James Marshall AC FRACP FRS FAA is an Australian physician, Nobel Prize Laureate in Physiology or Medicine, and Professor of Clinical Microbiology at the University of Western Australia. https://www.uwa.edu.au/profile/barry-marshall Additional links of interest: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(05)67587-3/fulltext  https://www.science.org.au/learning/general-audience/history/interviews-australian-scientists/professor-barry-marshall/teacher  See omnystudio.com/listener for privacy information.

Robin Warren of Corrello tells me how he finds and recruits freelance developers for his bootstrapped software company. We also talk about: Robin’s business creating Trello Power-ups Using Product Hunt to hone your marketing message Juggling multiple products Links: Robin on Twitter Corrello Blue Cat Reports Burndown Charts by Corrello Robin’s previous interview on the […] The post #154: Finding and recruiting freelance developers with Robin Warren of Corrello appeared first on Bootstrapped.fm.

Robin Warren of Corrello tells me how he finds and recruits freelance developers for his bootstrapped software company.We also talk about:Robin's business creating Trello Power-upsUsing Product Hunt to hone your marketing messageJuggling multiple productsLinks:Robin on TwitterCorrelloBlue Cat ReportsBurndown Charts by CorrelloRobin's previous interview on the Bootstrapped podcast 

In this podcast episode, we interview Barry Marshall, AC, FRACP, FRS, FAA, the legendary Nobel Laureate who discovered that peptic ulcer disease was caused by the bacteria Helicobacter pylori, not excess acid. Marshall fought for years against the notion that ulcers were caused by acid and finally infected himself with the bacteria and underwent endoscopy to prove his point. His research has saved countless lives, as untreated ulcer disease can lead to gastric cancer. We discuss numerous facets of his life and his pioneering work. Before antimicrobial therapy against Helicobacter, patients suffered for years without the right therapy.  Brought to you by Redhill Biopharma, makers of Talicia (omeprazole magnesium, amoxicillin and rifabutin) delayed release capsules. Visit talicia.com for more information, including full prescribing information. Intro :35 About Dr. Marshall :37 The interview 3:30 Tell us about your upbringing. What was your childhood like? 3:38 How did you meet Robin Warren? 6:35 What was your ah-ha moment that made you want to follow it through? 13:11 Brought to you by Redhill Biopharma, makers of Talicia (omeprazole magnesium, amoxicillin and rifabutin) delayed release capsules. Visit talicia.com for more information, including full prescribing information. 40:56 Were you met with skepticism? 41:13 How did you interact with the naysayers at the time? 51:46 What drove you to infect yourself with H. pylori? 1:01:28 What was it like to win the Nobel prize? 1:10:14 What advice do you have for young faculty members or GI fellows embarking on an investigative career? 1:18:18 Thank you, Dr. Marshall 1:22:30 Barry Marshall, AC, FRACP, FRS, FAA, is an Australian physician, Nobel Prize Laureate in Physiology or Medicine, and professor of clinical microbiology at the University of Western Australia. We’d love to hear from you! Send your comments/questions to guttalkpodcast@healio.com. Follow us on Twitter @HealioGastro @sameerkberry @umfoodoc Disclosures: Berry and Chey report no relevant financial disclosures. Healio was unable to confirm relevant financial disclosures for Marshall at the time of publication.

Is a Young Earth Possible? argues for a youthful world from history and science. In the 1970’s, Australian doctors Robin Warren and Barry Marshall proposed that the bacteria Helicobacter pylori caused ulcers. It took two decades before their conclusion was justly recognized by the scientific establishment. Has Big Science misdated the earth? Is a Young Earth Possible? relates to a number of key issues in the public square such as climate change, homeschooling, government funding of science, bullying, depression, fake news, net censorship, and free speech. To learn more about Prof. Jay Hall and his work, visit www.YoungEarthScienceBook.com To get your copy of Is a Young Earth Possible?, please visit our Amazon.com affiliate link.

Is a Young Earth Possible? argues for a youthful world from history and science. In the 1970’s, Australian doctors Robin Warren and Barry Marshall proposed that the bacteria Helicobacter pylori caused ulcers. It took two decades before their conclusion was justly recognized by the scientific establishment. Has Big Science misdated the earth? Is a Young Earth Possible? relates to a number of key issues in the public square such as climate change, homeschooling, government funding of science, bullying, depression, fake news, net censorship, and free speech.To learn more about Prof. Jay Hall and his work, visit www.YoungEarthScienceBook.comTo get your copy of Is a Young Earth Possible?, please visit our Amazon.com affiliate link.To learn more about Provocative Enlightenment Radio, go to http://www.provocativeenlightenment.com

In this episode Craig sits down with Robin Warren of Corrello. They talk through managing the risk of building an extension to an existing platform, doing user testing to release better products the first time, and how Covid-19 is affecting our businesses (and personal lives). Robin’s team has just finished a long (multi-year) development project […]

Robin and I discuss living the Bootstrapper dream – and how the dream changes over time. We also go off topic and discuss surfing up the Bristol Channel. Links: Robin’s company, Corrello: Dashboards for Scrum and Kanban teams using Trello: https://getcorrello.com/ Robin on Twitter: https://twitter.com/robinwarren Robin’s blog post “$0 to $1k MRR in 57 months”: […] The post #110: “Living the Bootstrapper dream” with Robin Warren, founder of Corrello appeared first on Bootstrapped.fm.

Robin and I discuss living the Bootstrapper dream - and how the dream changes over time. We also go off topic and discuss surfing up the Bristol Channel. Links: Robin’s company, Corrello: Dashboards for Scrum and Kanban teams using Trello: https://getcorrello.com/ Robin on Twitter: https://twitter.com/robinwarren Robin's blog post "$0 to $1k MRR in 57 months": https://getcorrello.com/blog/2016/04/13/0-1k-mrr-57-months/ Britstrapped podcast interview with Robin, From 0 MRR to "Living the Dream": http://www.britstrapped.com/280d7224 Surfing up the Bristol channel: https://www.youtube.com/watch?v=IKA39LQOIck

This week's episode comes with a warning: don't attempt this at home. While self-experimentation has led to many a scientific breakthrough, we're definitely not advocating it. But it happened to work out for the best for Barry Marshall and Robin Warren, even earning them a Nobel prize. That’s right folks, today we’re talking about none other than Helicobacter pylori, the curvy little bacterium identified only a few decades ago to be a causative agent of peptic ulcer disease, a major risk factor in the development of gastric cancer, and a fierce warrior who can survive the harshest of environments: your stomach.

In our first episode, Corry tells the story of an Australian scientist that drank a beaker of bacteria just to prove a point! We also discuss how Easter cured stomach ulcers and, of course, what Luke’s therapist has been saying... References & Further Reading 1. "In pursuit of diseases that have no name" (https://www.theguardian.com/science/2010/oct/17/genetics-undiagnosed-diseases) 2. "The Doctor Who Drank Infectious Broth, Gave Himself an Ulcer, and Solved a Medical Mystery" (http://discovermagazine.com/2010/mar/07-dr-drank-broth-gave-ulcer-solved-medical-mystery) 3. BarryJ Marshall, J.Robin Warren, UNIDENTIFIED CURVED BACILLI IN THE STOMACH OF PATIENTS WITH GASTRITIS AND PEPTIC ULCERATION (http://www.sciencedirect.com/science/article/pii/S0140673684918166) , The Lancet 4. "Helicobacter pylori - Chapter 3 - 2016 Yellow Book | Travelers' Health | CDC".  5. Barry, Marshall (2005). "Autobiography". Nobel Foundation.  6. Marshall BJ, Warren JR (June 1984). "Unidentified curved bacilli in the  stomach of patients with gastritis and peptic ulceration". Lancet. 1  7. Konturek JW (December 2003). "Discovery by Jaworski of Helicobacter pylori and its pathogenetic role in peptic ulcer, gastritis and gastric cancer"  8. Steer HW (August 1975). "Ultrastructure of cell migration through the gastric epithelium and its relationship to bacteria"  9. Atwood IV KC (2004). "Bacteria, Ulcers, and Ostracism? H. pylori and the making of a myth" Support us on Patreon: http://patreon.com/SciGuys Watch us on YouTube: http://youtube.com/SciGuys Follow the Sci Guys @notcorry / @jampkin / @lukecutforth

It was arguably THE GUT that brought Dr Michael Mosley his earliest public recognition. His 1994 documentary on the work of West Australian researchers Professor Barry Marshall and Dr Robin Warren brought nominations for an Emmy, A BAFTA and also brought a LOT of mail. The experience marked the realization that Hippocrates was on to something 2500 years ago when he said “All disease begins in the gut” Dr Mosley has made countless documentaries since, often experimenting on himself. He's ALSO authored several books including the 5:2 Diet, the eight week blood sugar diet and the Clever Guts diet….which have gleaned the best advice he's gathered on how to prolong good health. It was a privilege to host Dr Mosley at the Sugarland Studio in Perth Western Australia during his recent Australian Tour. Music: The Summit by Blue Dot Sessions sourced via freemusicarchive.org

It was arguably THE GUT that brought Dr Michael Mosley his earliest public recognition. His 1994 documentary on the work of West Australian researchers Professor Barry Marshall and Dr Robin Warren brought nominations for an Emmy, A BAFTA and also brought a LOT of mail. The experience marked the realization that Hippocrates was on to something 2500 years ago when he said “All disease begins in the gut” Dr Mosley has made countless documentaries since, often experimenting on himself. He’s ALSO authored several books including the 5:2 Diet, the eight week blood sugar diet and the Clever Guts diet….which have gleaned the best advice he’s gathered on how to prolong good health. It was a privilege to be able to host Dr Mosley at the Sugarland Studios in Perth during his June 2018 tour.

Dr Sean Stevens sits down with Clinical Professor of Microbiology at University of Western Australia and Nobel Prize recipient Professor Barry Marshall. In this episode, Barry talks about life growing up, his pathway to medicine and the start of his collaborative relationship with Dr Robin Warren.

This week, Martin catches up with Robin Warren from Corrello. We talk about getting from 0 MRR to an amount you can live on.

Justin talks to Robin Warren about his bootstrapped startup Corrello, a dashboard for agile teams using Trello.

This week, Martin interviews Robin Warren, founder of Corrello, a SaaS app which provides dashboards for agile teams using Trello.

This is the podcast with Professor Barry Marshall and Professor Emad El-Omar to accompany the #FGDebate entitled 'Frontline Research: The highs and lows of academic life - the basics, the barriers and the breakthroughs' held on Sunday 21st December 2014. Professor Barry Marshall is a an honorary Clinical Professor of Medicine and Pharmacology at Sir Charles Gairdner Hospital, University of Western Australia. Amongst his many international accolades, in 2005 Professor Marshall and Robin Warren were awarded the Nobel Prize for Physiology or Medicine in recognition of their 1982 discovery that a bacterium, Helicobacter pylori, causes one of the most common and important diseases of mankind, peptic ulcer disease. This discovery was the first step in developing more effective treatments for ulcers and in understanding the causative link between H. pylori and stomach cancer. Professor Emad El-Omar is the Chair of Gastroenterology at Aberdeen University, Scotland. He is also an Honorary Consultant Physician with NHS Grampian. Amongst his many international accolades and Editorial board positions, he is the Editor in Chief of the journal Gut. His main research interests are in the role of microbially-induced inflammation in GI cancer and inflammatory bowel disease. His group has strong collaborations with national groups within the UK and international groups in the US, Europe, Asia and Australia. We hope you enjoy it and wish you a Happy Christmas and New Year 2015 from all the Frontline Gastroenterology and Gut team. View the accompanying slides: http://goo.gl/2N5NrH Read the summary of the twitter debate: http://goo.gl/WWxlDC

El descubrimiento de que la bacteria Helicobacter pylori es la principal causante de úlceras de estómago e intestino –de duodeno, para ser precisos– llevó a ganar el premio Nobel de Fisiología y Medicina en 2005 a sus descubridores, los médicos australianos Robin Warren y Barry Marshal. Sin embargo, la manera en que Helicobacter pylori causa las tan temidas úlceras y problemas estomacales no estaba todavía esclarecida. Ahora, un grupo de investigadores de las Universidades de Cincinnati y de California, en EE.UU., han abordado esta cuestión y publican sus conclusiones en la revista PLOS Pathogens.

Bakterier förknippas ofta med fara och sjukdom. Men något håller på att hända, det forskas allt mer på deras goda sidor. Ett exempel är magsårsbakterien helicobacter pylori som blev världsberömd när Barry Marshall och Robin Warren fick nobelpriset 2005. De hade bevisat att bakterien leder till magsår som i sin tur kan orsaka magcancer och helicobacter pylori skulle utrotas med antibiotika. I dag menar kritiker att bakterien också har goda sidor och att barn som saknar den löper större risk att drabbas av astma och fetma. I veckans Kropp & Själ djupdyker vi i bakteriernas dubbla ansikte, att de kan göra oss sjuka vet vi, men på vilket sätt kan de hjälpa oss? Martin Blaser, professor i microbiologi vid New Yorks universitet, är den främsta kritikern mot bilden av magsårsbakterien helicobacter pylori som något som ska utrotas; ”Pendeln har svängt, helicobacter Pylori, har två ansikten, och vi har fokuserat för mycket på det negativa.” menar han. Även på andra håll studeras bakteriernas positiva effekter, på flera sjukhus används donerad avföring för att bota magåkommor. Genom att föra in friska bakterier i en sjuk person kan tarmfloran, i bästa fall, normaliseras. En annan fråga som studeras är huruvida allergier kan påverkas genom att mammor ges vissa bakterier under graviditeten. Thomas Abrahamsson, barnläkare och forskare vid Linköpings universitet, berättar om en stor studie där kvinnor ges mjölksyrebakterier efter den tjugonde graviditetsveckan. Gäst i studion är även professor Lars Engstrand vid Karolinska institutet som forskat om bakterier och deras påverkan på människan i över två decennium.

This recording was made in my living room in 1998; we called our trio Wry Whiskey. I'm picking banjo and singing, such as it is. The guitar player was Brian Clancey, who now plays in a duet with fiddler Robin Warren as Spirit Fiddle. Brian is the best back-up guitar player I ever heard, bar none. Here he is fingerpicking; we experimented a lot with the mixing together of finger style banjo and guitar. Tom Speth was the bass player; his knees have given out, and so he doesn't play much music anymore, but we've gone fishing together a few times over the last several years, which is almost as much fun.

This recording was made in my living room in 1998; we called our trio Wry Whiskey. I'm picking banjo and singing, such as it is. The guitar player was Brian Clancey, who now plays in a duet with fiddler Robin Warren as Spirit Fiddle. Brian is the best back-up guitar player I ever heard, bar none. Here he is fingerpicking; we experimented a lot with the mixing together of finger style banjo and guitar. Tom Speth was the bass player; his knees have given out, and so he doesn't play much music anymore, but we've gone fishing together a few times over the last several years, which is almost as much fun.

This recording was made in my living room in 1998; we called our trio Wry Whiskey. I'm picking banjo and singing, such as it is. The guitar player was Brian Clancey, who now plays in a duet with fiddler Robin Warren as Spirit Fiddle. Brian is the best back-up guitar player I ever heard, bar none. Here he is fingerpicking; we experimented a lot with the mixing together of finger style banjo and guitar. Tom Speth was the bass player; his knees have given out, and so he doesn't play much music anymore, but we've gone fishing together a few times over the last several years, which is almost as much fun.