Podcasts about ppis

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Best podcasts about ppis

Latest podcast episodes about ppis

Vitality Radio Podcast with Jared St. Clair
#582: The Myth of Safety: Hidden Dangers of Over-the-Counter Drugs

Vitality Radio Podcast with Jared St. Clair

Play Episode Listen Later Oct 29, 2025 27:29


Most people assume that if a drug sits on the shelf at Costco or Walgreens, it must be pretty safe. But what if some of the most common over-the-counter (OTC) medications are among the riskiest drugs in America? On this episode of Vitality Radio, Jared exposes the hidden dangers behind everyday pain relievers, sleep aids, and heartburn drugs—medicines that cause thousands of deaths every year when misused or taken long-term. You'll learn how a drug becomes “OTC,” what happens when pharmaceutical companies push for that switch, and why the FDA's approval process might not tell the whole story. Jared dives into the startling realities of PPIs like Prilosec, NSAIDs like ibuprofen, and acetaminophen (Tylenol)—uncovering their risks to the liver, kidneys, bones, and brain. He also discusses how marketing convinces consumers these drugs are harmless. Finally, Jared offers a resource for safe, natural alternatives for reflux, pain, inflammation, sleep, and immune support—options that nourish the body instead of depleting it. This episode will change the way you look at “harmless” OTC drugs and help you take real control of your health.Just Ingredients Lemon Swish Protein Powder Vitality Radio POW! Product of the Week $29.99 per bag (regular price $59.99) with PROMO CODE: POW15Additional Information:#341: Your Digestive Health Supplement User's Guide. From IBS to Acid Reflux - Learn How to Balance Your Gut Health With Natural Products. #522: Q&A Show #5 - Jared Answers Your Questions About Energy and Sleep!#471: Boosting Your Immune System Ahead of Winter #553: Boswellia & Curcumin: Nature's Dream Team for Pain & Inflammation with Dr. Lexi LochVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

The Low Carb Athlete Podcast
#616 Are Root Canals Making You Sick? Oral Infections, Vagus Nerve & CIRS with Dr. Michelle Jorgensen

The Low Carb Athlete Podcast

Play Episode Listen Later Oct 28, 2025 54:58


Root Canals, Dental Infections & Chronic Illness with Dr. Michelle Jorgensen Could your teeth be the hidden root cause of your health struggles? In this episode of The Coach Debbie Potts Show, I sit down with Dr. Michelle Jorgensen—biological dentist, functional health expert, and author—to uncover the surprising ways oral health impacts your immune system, hormones, brain, and even your longevity. We discuss: ✅ What really happens in a root canal and why they can fail over time ✅ How hidden dental infections and bacteria in root canals can spread endotoxins through the body ✅ The connection between mercury fillings, acetylcholine, and vagus nerve dysfunction ✅ Why nasal breathing—not mouth breathing—is essential for oxygen, nitric oxide, and sleep quality ✅ CPAP machines: why they aren't always the root cause solution for sleep apnea ✅ How gut health, PPIs, and mineral balance affect your teeth and bones ✅ Holistic options for safer dentistry—ozone therapy, implants, and myofunctional therapy ✅ Practical steps to identify if your dental health is draining your energy or fueling chronic illness If you've wondered about the link between root canals, CIRS (Chronic Inflammatory Response Syndrome), mold, and biotoxin illness, this conversation will give you new insights and hope for root-cause healing.

Schwuler gehts nicht
Pat verteilt Schlüppis, aber Sebastian macht sich ausm Staub

Schwuler gehts nicht

Play Episode Listen Later Oct 25, 2025 67:57


chwuler geht's nicht - Folge 273! Von geplatzten Dates, Schüssen und Wohnungsbränden in der Nachbarschaft, sowie zu lang angemeldeten Menschen auf Datingplattformen und der Frage: Warum verheilt man Schlüpfer im GYM?

THE BETTER BELLY PODCAST - Gut Health Transformation Strategies for a Better Belly, Brain, and Body
287// How to safely get off PPI's and reverse acid reflux naturally

THE BETTER BELLY PODCAST - Gut Health Transformation Strategies for a Better Belly, Brain, and Body

Play Episode Listen Later Oct 23, 2025 19:39


Have you ever wondered how to get OFF your PPI safely - without hurting your body in the process? This is one of the most common questions I get from my clients who are struggling with acid reflux. And I get it. I've worked with clients on 1 PPI a day… 2 PPIs a day… even 3 PPIs a day PLUS tums and antacids stacked on top. I've worked with a client told by doctors at the University of Michigan that there was nothing left they could do for her. And I've gotten clients like her all the way down to ZERO PPIs. Here's the thing: if you're on a PPI, your acid reflux is probably pretty severe. Stopping cold turkey can leave you in pain, afraid to eat, and stuck in fear. So - how do you get off PPIs safely? That is exactly what we're covering today. On today's episode, we're diving into: The #1 thing stopping you from getting off PPIsHow to taper off PPIs without painStories of clients who've ended 20+ and even 40+ years of acid reflux with this approach If you're ready to finally end your reflux for good - this episode is for you. TIMESTAMPS:00:00 - Introduction: Safely Getting Off PPIs 01:14 - Welcome to the Better Belly Podcast 02:24 - Understanding the Fear of Stopping PPIs 05:28 - Steps to Safely Taper Off PPIs 06:53 - The Better Belly Blueprint Program 10:01 - Monitoring Symptoms and Adjusting PPIs 17:37 - Client Success Stories 19:03 - Conclusion and Next Steps EPISODES MENTIONED:285// Two Steps to Reversing Your Acid Reflux (for good!)Acid reflux testimonials:Andrea - 200// How to End 20+ Years of Constipation and Acid Reflux in 3 MonthsDon - 242// How He Ended 40+ Years of Diarrhea, Bloating, and Acid Reflux (Don's Testimonial)Jamie - 249// She Beat Her Bloat, Constipation, and Acid Reflux in One Month HEAL YOUR GUT TODAY!Option #1)

THE BETTER BELLY PODCAST - Gut Health Transformation Strategies for a Better Belly, Brain, and Body
287// How to safely get off PPI's and reverse acid reflux naturally

THE BETTER BELLY PODCAST - Gut Health Transformation Strategies for a Better Belly, Brain, and Body

Play Episode Listen Later Oct 23, 2025 19:39


Have you ever wondered how to get OFF your PPI safely - without hurting your body in the process? This is one of the most common questions I get from my clients who are struggling with acid reflux. And I get it. I've worked with clients on 1 PPI a day… 2 PPIs a day… even 3 PPIs a day PLUS tums and antacids stacked on top. I've worked with a client told by doctors at the University of Michigan that there was nothing left they could do for her. And I've gotten clients like her all the way down to ZERO PPIs. Here's the thing: if you're on a PPI, your acid reflux is probably pretty severe. Stopping cold turkey can leave you in pain, afraid to eat, and stuck in fear. So - how do you get off PPIs safely? That is exactly what we're covering today. On today's episode, we're diving into: The #1 thing stopping you from getting off PPIsHow to taper off PPIs without painStories of clients who've ended 20+ and even 40+ years of acid reflux with this approach If you're ready to finally end your reflux for good - this episode is for you. TIMESTAMPS:00:00 - Introduction: Safely Getting Off PPIs 01:14 - Welcome to the Better Belly Podcast 02:24 - Understanding the Fear of Stopping PPIs 05:28 - Steps to Safely Taper Off PPIs 06:53 - The Better Belly Blueprint Program 10:01 - Monitoring Symptoms and Adjusting PPIs 17:37 - Client Success Stories 19:03 - Conclusion and Next Steps EPISODES MENTIONED:285// Two Steps to Reversing Your Acid Reflux (for good!)Acid reflux testimonials:Andrea - 200// How to End 20+ Years of Constipation and Acid Reflux in 3 MonthsDon - 242// How He Ended 40+ Years of Diarrhea, Bloating, and Acid Reflux (Don's Testimonial)Jamie - 249// She Beat Her Bloat, Constipation, and Acid Reflux in One Month HEAL YOUR GUT TODAY!Option #1)

The Turd Nerds
#71 - Rethinking Reflux Meds

The Turd Nerds

Play Episode Listen Later Oct 21, 2025 36:33


In this conversation, The doctors discusses the implications of long-term use of Proton Pump Inhibitors (PPIs), their efficacy, risks, and the importance of tapering off these medications. The discussion covers the physiological effects of PPIs, the necessity of addressing underlying causes of reflux, and the potential for natural and herbal alternatives to support patients in tapering off PPIs. The conversation emphasizes the importance of patient education and the need for a gradual approach to discontinuing PPIs to avoid rebound symptoms.TakeawaysPPIs are effective for short-term use but not for long-term.Tapering off PPIs should take three to six months.Natural alternatives can help manage reflux symptoms.Melatonin can improve lower esophageal sphincter function.Nutrient deficiencies are a risk with long-term PPI use.DGL has been shown to improve quality of life in patients.Patient education is crucial in managing PPI use.Underlying causes of reflux should be addressed.Herbal remedies can provide additional support during tapering.A gradual tapering process is essential to avoid rebound symptoms.

THE BETTER BELLY PODCAST - Gut Health Transformation Strategies for a Better Belly, Brain, and Body

Are you tired of chasing your acid reflux symptoms with PPI's, annoying food restrictions like the GERD diet, or hyper-vigilance about when and how much food you eat? When you ask your doctor if there's ANYTHING else you can do to help your acid reflux, do they tell you that you just need to pop another antacid, avoid trigger foods, or sleep on a wedge pillow? Do you wish there was a solution to acid reflux that was permanent, so you could eat late at night without worrying about a reflux flare, or that you could eat your favorite foods again without feeling punished for it later? If you said yes to any of these questions, then this episode is for you. On today's episode, my goal is to lay out acid reflux in one MASTER episode so that, by the end of it, you can have a map for exactly how to find, and deal with, the root cause(s) of your acid reflux. In this episode, I'm talking about: The real causes of acid reflux and GERD symptoms (and why it's not “too much acid”)The difference between acid reflux, GERD, LPR, and silent reflux — and why this episode can help ALL of these diagnosesWhy standard acid reflux drugs (PPIs, acid reducers) give quick relief but cause long-term problemsHow the acid reflux diet and GERD diet miss the root causeAnd, most importantly, 2 steps to reversing your acid reflux (for good!) If you're tired of relying on medication to manage your acid reflux and want freedom from your stomach terror - then this episode is for you. TIMESTAMPS:00:00 - Introduction to Acid Reflux Struggles 00:56 - Understanding Acid Reflux and GERD 01:44 - Welcome to the Better Belly Podcast 04:27 - The Anatomy and Symptoms of Acid Reflux 08:16 - Diagnosing Acid Reflux 10:24 - Causes of Acid Reflux 13:00 - Pressure Systems and Acid Reflux 25:49 - Conventional Treatments for Acid Reflux 28:25 - The Impact of Low Stomach Acid on Nutrient Absorption 29:32 - The Vicious Cycle of PPIs and Acid Reflux 31:29 - Steps to Reverse Acid Reflux 33:37 - Identifying Pathogens and Their Effects 40:09 - The Role of Histamine in Acid Reflux 40:49 - Fascial Restrictions and Their Impact 44:53 - Testing for Low Stomach Acid 48:05 - Comprehensive Testing and Treatment Plan 51:22 - Client Success Stories and Testimonials 53:08 - Conclusion and Next Steps EPISODES MENTIONED:47// The Gut-Sinus Connection233// H. Pylori: Symptoms of H. Pylori, How to Interpret H. Pylori Test Results, and Why H. Pylori Treatments Fail40// Reduce Acid Reflux with the Magic Power of Zinc68// 10 Markers on Your Bloodwork Linked to Acid Reflux

THE BETTER BELLY PODCAST - Gut Health Transformation Strategies for a Better Belly, Brain, and Body

Are you tired of chasing your acid reflux symptoms with PPI's, annoying food restrictions like the GERD diet, or hyper-vigilance about when and how much food you eat? When you ask your doctor if there's ANYTHING else you can do to help your acid reflux, do they tell you that you just need to pop another antacid, avoid trigger foods, or sleep on a wedge pillow? Do you wish there was a solution to acid reflux that was permanent, so you could eat late at night without worrying about a reflux flare, or that you could eat your favorite foods again without feeling punished for it later? If you said yes to any of these questions, then this episode is for you. On today's episode, my goal is to lay out acid reflux in one MASTER episode so that, by the end of it, you can have a map for exactly how to find, and deal with, the root cause(s) of your acid reflux. In this episode, I'm talking about: The real causes of acid reflux and GERD symptoms (and why it's not “too much acid”)The difference between acid reflux, GERD, LPR, and silent reflux — and why this episode can help ALL of these diagnosesWhy standard acid reflux drugs (PPIs, acid reducers) give quick relief but cause long-term problemsHow the acid reflux diet and GERD diet miss the root causeAnd, most importantly, 2 steps to reversing your acid reflux (for good!) If you're tired of relying on medication to manage your acid reflux and want freedom from your stomach terror - then this episode is for you. TIMESTAMPS:00:00 - Introduction to Acid Reflux Struggles 00:56 - Understanding Acid Reflux and GERD 01:44 - Welcome to the Better Belly Podcast 04:27 - The Anatomy and Symptoms of Acid Reflux 08:16 - Diagnosing Acid Reflux 10:24 - Causes of Acid Reflux 13:00 - Pressure Systems and Acid Reflux 25:49 - Conventional Treatments for Acid Reflux 28:25 - The Impact of Low Stomach Acid on Nutrient Absorption 29:32 - The Vicious Cycle of PPIs and Acid Reflux 31:29 - Steps to Reverse Acid Reflux 33:37 - Identifying Pathogens and Their Effects 40:09 - The Role of Histamine in Acid Reflux 40:49 - Fascial Restrictions and Their Impact 44:53 - Testing for Low Stomach Acid 48:05 - Comprehensive Testing and Treatment Plan 51:22 - Client Success Stories and Testimonials 53:08 - Conclusion and Next Steps EPISODES MENTIONED:47// The Gut-Sinus Connection233// H. Pylori: Symptoms of H. Pylori, How to Interpret H. Pylori Test Results, and Why H. Pylori Treatments Fail40// Reduce Acid Reflux with the Magic Power of Zinc68// 10 Markers on Your Bloodwork Linked to Acid Reflux

Rennthusiast Radio
Why You'll Never Really Make Money on a Porsche (And Why That's Okay)

Rennthusiast Radio

Play Episode Listen Later Oct 7, 2025 41:10


Will and Derek just got back from rallying through the Blue Ridge and Smoky Mountains before spending the weekend at Luftgekühlt 11 in Durham, North Carolina. From secret back-road routes around Blowing Rock to running laps at Bristol Motor Speedway, it was two days of incredible driving followed by the most artfully curated Porsche event on the planet — courtesy of Patrick Long and Jeff Zwart at the historic Lucky Strike factory.In the intro, Derek gives a full recap of the week: Then we roll into one of our favorite classic episodes — “The Big Lie: Making Money on Every Porsche.” We dig deep into:The myth of always profiting on Porsche ownershipThe hidden costs (taxes, insurance, PPIs, must-dos vs. nice-to-dos)Why ceramic and PPF are often sunk costsThe ethics of selling and what it means to be a good stewardWhy breaking even might actually mean you're winningSo grab your coffee, settle in, and enjoy a mix of mountain-road storytelling and Porsche ownership truth-talk.Related videos: • Will's new 993 video → @Rennthusiast • Derek's Luft Shorts + Boxster first drive → @ElevenAfterNine #Porsche #Porsche911 #Luftgekühlt #PorscheLife #CarPodcast #RennthusiastRadio #PorscheOwnership #PorscheCulture #CarTalk #BlueRidgeParkway #PorscheCommunity #AirCooledPorsche #WaterCooledPorsche Hosted on Acast. See acast.com/privacy for more information.

BS Free MD with Drs. May and Tim Hindmarsh
395 — Dr. Nathan Bryan: Hormones, Heart & Skin—Surprising Roles for Nitric Oxide

BS Free MD with Drs. May and Tim Hindmarsh

Play Episode Listen Later Oct 2, 2025 74:00


Molecular-medicine expert Dr. Nathan Bryan explains how nitric oxide (NO) protects the endothelium, drives vasodilation, and influences energy, immunity, hormones, and longevity. He links stubborn hypertension and poor exercise tolerance to the microbiome–NO axis and outlines common NO killers—antiseptic mouthwashes and fluoride overuse, chronic PPIs, ultra-processed diets, and inactivity. We cover practical restores (movement, nutrient-dense food, targeted micronutrients, careful PPI weaning, ditching antiseptic rinses) and preview clinical work on NO-releasing lozenges for ischemic heart disease, approaches to improve cerebral blood flow and insulin signaling in cognitive decline, and topical NO for chronic wounds. Bryan also touches on food quality (glyphosate, soil health), hormone synergy with NO, and NO-based skincare that supports perfusion and collagen. Bottom line: rebuild NO, and the body's own repair systems can finally do their job.(Educational only; not personal medical advice.)Guest BioNathan S. Bryan, PhD is a molecular medicine researcher and leading authority on nitric oxide (NO) biochemistry. Over two decades, he has mapped how the body generates and uses NO—and what happens when it doesn't—publishing widely, authoring multiple books, and translating discoveries into products and late-stage drug trials. His work spans cardiovascular health, metabolism, neurocognition, wound healing, and skin biology, with a focus on restoring NO as a foundation for repair. Dr. Bryan speaks globally on NO and leads development of NO-based therapeutics targeting ischemic heart disease, Alzheimer's disease, and non-healing ulcers. GET SOCIAL WITH US!

Satte Sache | Ernährung, Gesundheit & Wohlbefinden
Stiller Reflux: Die unterschätzte Ursache für Heiserkeit, Husten und Schleim im Hals

Satte Sache | Ernährung, Gesundheit & Wohlbefinden

Play Episode Listen Later Oct 2, 2025 25:34


Emma – Schlaf, auf den Du zählen kannst: https://shorturl.at/2sGJo SATTESACHE | 5% on Top auf alles in der gesamten DACH-Region. Du bist ständig heiser, räusperst dich dauernd oder hast einen Kloß im Hals – aber niemand findet eine Ursache? Dann solltest du diese Episode nicht verpassen. Denn genau das kann auf stillen Reflux (LPR) hinweisen – eine Form von Reflux, die ganz ohne Sodbrennen verläuft und trotzdem weitreichende Beschwerden verursacht.

Beyond Wellness Radio
Protein Myths Debunked: What Really Damages Your Kidneys | Podcast #463

Beyond Wellness Radio

Play Episode Listen Later Oct 1, 2025 37:00


Life, Money & Love with Dylan Mullan
The Science of High Performance: How To Optimise Your Supplements, Sleep & Testosterone!

Life, Money & Love with Dylan Mullan

Play Episode Listen Later Oct 1, 2025 112:01


In this episode, I sat down with Lucas Aoun, Australia's leading expert in biohacking, nootropics, and human optimisation. Known online for his deep dives into energy, hormones, and supplements, Lucas has built a powerful personal brand helping thousands of people around the world take back control of their health.With nearly 100,000 followers on Instagram, a booming supplement funnel, and years of experience researching the science behind performance, he's become the go-to voice for people who want more energy, better sleep, sharper focus, and stronger results - both in business and in life.After years of trial and error, he stopped relying on traditional medicine, turned his back on caffeine, and began building the ultimate entrepreneur's supplement stack. What started as a way to heal himself soon became a growing business — one that now helps people optimise their health, think clearer, and perform better than ever.Get ready to rethink your health, your habits, and what's actually possible.In this episode:How Lucas hit rock bottom with gut issues and energy crashes — and the radical steps he took to rebuild his health from scratch.Quitting caffeine cold turkey after years of addiction and the surprising way it changed his brain, focus and mood.The real reason you wake up tired and crash at 3PM, and the daily habits Lucas changed to feel superhuman without stimulants.Why most supplement stacks don't work (and how Lucas built a custom stack that actually delivers results).The shocking truth about PPIs, antacids and how they destroy your gut health — even when doctors say they're safe.Lucas's $97 supplement funnel and how he built a scalable health business using personalisation.How he bounced back from being shadowbanned for years during COVID and rebuilt his online brand from scratch.What testosterone, DHT and hair loss actually mean for your energy, confidence and drive (and what you can do about it).—Get Shopify for $1

Rennthusiast Radio
Buying a Porsche Is Fun. Selling… Not So Much. How to Do It Right

Rennthusiast Radio

Play Episode Listen Later Sep 30, 2025 46:50


Buying a Porsche is the fun part—selling it? Not so much. In this episode of Rennthusiast Radio, Derek and Will break down the right way to sell your Porsche without wasting time, money, or sanity. From prepping your car for sale, to pricing it correctly, to knowing whether PCA classifieds, Rennlist, Bring a Trailer, or Cars & Bids is the right platform—we've got you covered.We'll share the mistakes we've seen sellers make (“testing the waters,” anyone?), how to present your Porsche with pro-level photos and videos, and the insider details buyers look for: PPIs, DME reports, binders of receipts, and even paint-meter readings.Whether you're moving on from your first 911 or your tenth Cayenne, this episode is your playbook for selling smarter.Topics Covered:Why “testing the waters” turns buyers offWhere to list: PCA, Rennlist, BaT, Cars & Bids, Facebook MarketplacePricing strategies that actually workPhotos, videos, and presentation tips that sell carsReceipts, PPIs, and Porsche “nerd catnip” buyers loveWhen to pull the trigger and get the deal doneSubscribe to Rennthusiast Radio and ElevenAfterNine for real Porsche ownership talk, no fluff. #Porsche #RennthusiastRadio #Porsche911 #PorscheBoxster #PorscheCayman #PorscheLife #PorscheForSale #BringATrailer #CarsAndBids #Rennlist #PorscheCommunity Hosted on Acast. See acast.com/privacy for more information.

Welltopia Capsule with Omar the pharmacist
Omar The Pharmacist At The Earl Ingram Show LIVE - Hidden Dangers of Your Meds: Are You Depleting Your Health?- Thursday, August 11th, 2025

Welltopia Capsule with Omar the pharmacist

Play Episode Listen Later Sep 30, 2025 42:31


Omar The Pharmacist and Earl Ingram dive into the surprising risks of long-term medication use. They reveal how common drugs can deplete essential nutrients, leading to fatigue, muscle pain, and cognitive fog. Rph Omar highlights the importance of supplements, like magnesium with PPIs and CoQ10 with statins, to counteract these effects. They stress the necessity of building a relationship with a knowledgeable pharmacist, especially as insurance and big pharmacy chains often overlook patient education. As health costs rise, investing in quality supplements becomes crucial for maintaining vitality and combating the systemic challenges of modern healthcare.This conversation is all about empowering listeners with real tools to take charge of their health — physically, mentally, and emotionally. Stay tuned for more insightful health segments with Omar The Pharmacist on What's Goin' On with Earl Ingram

Health Longevity Secrets
Does Mouthwash Cause Hypertension? with Dr Nathan Bryan

Health Longevity Secrets

Play Episode Listen Later Sep 23, 2025 47:50 Transcription Available


Ever wondered how a single molecule can regulate blood flow, support neurotransmission, and boost immune defense? Dr. Bryan unravels these mysteries and cuts through the confusion with nitrous oxide, sharing invaluable insights from his collaborations with Nobel Prize winners. Join us as we explore why nitric oxide is pivotal to our health and longevity, and why it deserves more attention in medical circles.We also probe into the darker side of proton pump inhibitors (PPIs) and their detrimental effects on nitric oxide production. Through Dr. Bryan's expert lens, we examine the serious health risks tied to long-term PPI use, such as heart disease and cognitive decline, and highlight the hidden dangers of fructose metabolism in suppressing nitric oxide synthase. Our discussion underscores the importance of understanding these complex interactions and the need for increased awareness among both medical professionals and patients.Not stopping there, we venture into the fascinating interplay between erectile dysfunction drugs and nitric oxide. Dr. Bryan explains how maintaining optimal nitric oxide levels can enhance the effectiveness of medications like Viagra and Cialis, with potential benefits for overall vascular health and longevity. We wrap up with practical advice for boosting nitric oxide naturally, including simple lifestyle changes and mindfulness around oral health products. Don't miss out on this opportunity to enrich your understanding and take proactive steps toward better health!https://n1o1.comLies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkinMimio Health (LUFKIN for 15% off) https://mimiohealth.sjv.io/c/5810114/2745519/30611 Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdInstagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: ...

emDOCs.net Emergency Medicine (EM) Podcast
Episode 126: Upper GI Bleeding Evidence and Controversies Part 2

emDOCs.net Emergency Medicine (EM) Podcast

Play Episode Listen Later Sep 15, 2025 19:51


Welcome to the emDOCs.net podcast! Join us as we review our high-yield posts from our website emDOCs.net. Today on the emDOCs cast with Brit Long, MD (@long_brit), we're back with Part 2 on upper GI bleeding.  Today we cover endoscopy, other interventions for bleeding cessation, intubation, and risk scores.  Please see Part 1 for some background, NG tube lavage, blood product transfusion, proton pump inhibitors (PPIs), prokinetic agents, somatostatin analogues, and antibiotics. To continue to make this a worthwhile podcast for you to listen to, we appreciate any feedback and comments you may have for us. Please let us know!Subscribe to the podcast on one of the many platforms below:Apple iTunesSpotifyGoogle Play 

emDOCs.net Emergency Medicine (EM) Podcast
Episode 125: Upper GI Bleeding Evidence and Controversies Part 1

emDOCs.net Emergency Medicine (EM) Podcast

Play Episode Listen Later Sep 2, 2025 18:42


Welcome to the emDOCs.net podcast! Join us as we review our high-yield posts from our website emDOCs.net.Today on the emDOCs cast with Brit Long, MD (@long_brit), we cover part 1 on upper GI bleeding, specifically some background, NG tube lavage, blood product transfusion, proton pump inhibitors (PPIs), prokinetic agents, somatostatin analogues, and antibiotics. To continue to make this a worthwhile podcast for you to listen to, we appreciate any feedback and comments you may have for us. Please let us know!Subscribe to the podcast on one of the many platforms below:Apple iTunesSpotifyGoogle Play

The Cabral Concept
3487: Female Hair Growth, Getting Rid of Mold, Smaller vs. Larger Meals, Creatine & Kidney Function, Eosinophilic Esophagitis & PPIs (HouseCall)

The Cabral Concept

Play Episode Listen Later Aug 23, 2025 17:32


Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions:    Sarah: Hello! Back with another question.. Im 28 female from scotland, and have had hair growing in places I shouldn't since age 24. The hair under my chin and a bit on my neck/cheeks is what gets me down the most. My doctor has checked me for PCOS through bloodwork and said everything was fine. I've recently did your hormone test. Testosterone was great, estrogen good, progesterone was low and cortisol was low. I've been on progesterone support, adrenal energy aswell as DNS, greens, omegas etc for some time now. I also take pumpkin seed oil and saw palmetto. The hair just keeps growing. What else can I do? I've tried countless rounds of laser but it just returns. Is hair in this area always related to PCOS/hormones? Can it just be genetics? Thank you!!                                                            Larissa: Hello! I was exposed to black mold for 6 yrs about 5yrs ago. Although my most severe symptoms went away, some longer. I've been working with a naturopath whom recommended a protocol with cholestyramine, charcoal, and minerals for about 1M. However, I've read Andrew Campbell mold protocol and he recommends itraconazole for 7 days. I did my urine mycotoxin testing FYI which still shows a high load of most all strains. Which do you recommend? I want to get rid of all the mold with the least side effects and avoiding constipation (I already have to take daily magnesium citrate to have daily bowel movements). Thank you!!!                                                                                                          Sabrina: Hi doctor Cabral. I'm hoping you can help me with something that is super frustrating. My stomach craves large meals for satisfaction, yet they cause bloating. Conversely, small-volume meals, despite being calorie-dense, just don't register as filling, leaving me wanting more. Is there a way to solve this, meaning training your stomach to be satisfied with smaller meals? Thanks so much for your help!                     Lisa: I am a 48yr old female and have elevated kidney function. 1.1.  have been told not to take creatine. I have heard multiple times that to much protein can have an effect on kidney function also. I love to workout and fir my age high protein and creatine is suppose to be good for someone who works out. Will these things truly hinder or further hinder my kidney function.                                                                                   Cassi: Just completed your book, The Rain Barrel Effect, and was wondering if you have worked with anyone with EOE (Eosinophilic esophagitis) to successfully get them off of PPIs? I've also dealt with histamine intolerance, that I've actually been able to reverse through a lot of what you teach in the book, and I have also gotten down from 20mg of omeprazole twice a day to 20mg once every other day but if I go longer than that I find myself choking on food again no matter how little I eat at a time or how well I chew it.      Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!    - - - Show Notes and Resources: StephenCabral.com/3487 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

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Dr. Jockers Functional Nutrition
The Most Dangerous Medication in the World and How to Get Off It

Dr. Jockers Functional Nutrition

Play Episode Listen Later Aug 1, 2025 17:59


In this episode, Dr. David Jockers dives into the dangers of proton pump inhibitors (PPIs), one of the most commonly prescribed medications worldwide. You'll learn why PPIs, though effective for acid reflux, can lead to serious health issues like heart disease, cancer, and nutrient deficiencies. Dr. Jockers explains how these medications only mask symptoms without addressing the root cause.   Discover how low stomach acid, not high acid, is often behind acid reflux and how PPIs can worsen digestion and overall health. Dr. Jockers shares practical strategies to naturally manage acid reflux, focusing on lifestyle and dietary changes rather than relying on medication.   Find out how long-term use of PPIs can increase your risk of early death, as well as the alternative solutions that actually promote better digestion and overall health. Tune in to understand why healing your gut should be the priority over simply masking symptoms.     In This Episode:  00:00 Introduction to Proton Pump Inhibitors (PPIs) 00:17 The Dangers of Blood Sugar Imbalances 02:27 Podcast Introduction and Overview 04:24 The Most Dangerous Medication: PPIs 05:16 How PPIs Affect Your Body 14:21 Natural Remedies and Lifestyle Changes 17:06 Conclusion and Final Thoughts   If you're dealing with blood sugar swings, stubborn fat, or constant cravings, Berberine Breakthrough by BiOptimizers could be the game-changer your body needs. This advanced formula goes beyond standard berberine by combining it with 12 synergistic ingredients like alpha-lipoic acid, chromium, and cinnamon to supercharge your metabolism, stabilize insulin levels, and fuel mitochondrial health. Users report better energy, fewer cravings, and noticeable fat loss — all backed by science. Plus, it comes with a 365-day money-back guarantee, so there's zero risk. Use code JOCKERS at bioptimizers.com/jockers to save 10% and start transforming your health today.     “PPIs don't fix acid reflux—they silence the symptoms while the damage continues.”  ~ Dr. Jockers     Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio     Resources: Use code JOCKERS at bioptimizers.com/jockers to save 10%     Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

The Human Upgrade with Dave Asprey
Why Big Pharma Hates Nitric Oxide (And How to Use It Anyway) : 1302

The Human Upgrade with Dave Asprey

Play Episode Listen Later Jul 17, 2025 53:57


If you care about longevity, brain optimization, sexual performance, or metabolism, this molecule changes everything. Host Dave Asprey sits down with nitric oxide pioneer Dr. Nathan Bryan to reveal why this overlooked molecule controls your blood flow, mitochondrial energy, neuroplasticity, insulin response, and even your libido. You'll learn how nitric oxide acts as a master switch for human performance and why the medical system has ignored it for decades. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dr. Nathan Bryan is a world-renowned expert in nitric oxide biochemistry with over 20 years of clinical research, multiple patents, and collaborations with Nobel Prize-winning scientists. His groundbreaking work forms the foundation for modern functional medicine protocols targeting blood flow, metabolism, cognitive enhancement, and mitochondrial upgrades. You'll learn: • How nitric oxide drives mitochondria, metabolism, and human performance • Why most nitric oxide supplements fail and how to spot real ones • The critical role nitric oxide plays in brain optimization, libido, and insulin signaling • How poor oral health, statins, and PPIs can kill nitric oxide production • What nitric oxide has to do with sleep optimization, aging, and disease prevention • How to stack nitric oxide with fasting, ketosis, nootropics, red light, and supplements • Why “Smarter Not Harder” starts with nitric oxide fueled upgrades This episode is essential listening for anyone into biohacking, cold therapy, functional medicine, or RFK-style medical freedom. You'll walk away with practical tools to boost nitric oxide naturally, prevent dysfunction, and optimize your biology whether you're on a carnivore diet or just looking for an edge. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Get Nitric Oxide products for 10% off with code ‘Dave': https://bit.ly/Nitric-Oxide-Product SPONSORS: Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources: • Nathan's Website: https://www.n1o1.com • Nathan's YouTube: https://www.youtube.com/channel/UCtftGy8e0r9DO8ActcyGi4w • Dave Asprey's Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:03 Intro • 01:15 Why Medicine Ignores Nitric Oxide • 01:59 What Nitric Oxide Does in the Body • 04:46 How the Body Makes Nitric Oxide • 07:12 Diet's Impact on NO Levels • 13:28 Why Most NO Supplements Fail • 19:32 Personalized Biohacking with NO • 22:33 How Medicine Misses the Mark • 30:40 Oral Health and Nitric Oxide • 31:30 Mouthwash Kills Your Microbiome • 32:28 The Problem with Fluoride • 33:25 Better Toothpaste for NO • 33:49 NO's Role in Energy and Healing • 34:17 Blood Pressure and NO • 35:29 NO and Sexual Performance • 37:09 NO and COVID Recovery • 40:50 Brain Fog and NO Deficiency • 49:01 Carnivore, Sugar, and NO • 50:11 Why You Still Need NO Supplements • 54:19 Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

featured Wiki of the Day

fWotD Episode 2991: Heartburn Welcome to featured Wiki of the Day, your daily dose of knowledge from Wikipedia's finest articles.The featured article for Sunday, 13 July 2025, is Heartburn.Heartburn is a burning sensation felt behind the breastbone. It is a symptom that is commonly linked to acid reflux and is often triggered by food, particularly fatty, sugary, spicy, chocolate, citrus, onion-based and tomato-based products. Lying down, bending, lifting, and performing certain exercises can exacerbate heartburn. Causes include acid reflux, gastroesophageal reflux disease (GERD), damage to the esophageal lining, bile acid, mechanical stimulation to the esophagus, and esophageal hypersensitivity. Heartburn affects 25% of the population at least once a month.Endoscopy and esophageal pH monitoring can be used to evaluate heartburn. Some causes of heartburn, such as GERD, may be diagnosed based on symptoms alone. Potential differential diagnoses for heartburn include motility disorders, ulcers, inflammation of the esophagus, and medication side effects. Lifestyle changes, such as losing weight and avoiding fatty foods, can improve heartburn. Over-the-counter alginates or antacids can help with mild or occasional heartburn. Heartburn treatment primarily involves antisecretory medications like H2 receptor antagonists (H2RAs) and proton-pump inhibitors (PPIs).This recording reflects the Wikipedia text as of 00:30 UTC on Sunday, 13 July 2025.For the full current version of the article, see Heartburn on Wikipedia.This podcast uses content from Wikipedia under the Creative Commons Attribution-ShareAlike License.Visit our archives at wikioftheday.com and subscribe to stay updated on new episodes.Follow us on Mastodon at @wikioftheday@masto.ai.Also check out Curmudgeon's Corner, a current events podcast.Until next time, I'm neural Ayanda.

Dr. Joseph Mercola - Take Control of Your Health
Are Acid Blockers Silently Destroying Your Health? - AI Podcast

Dr. Joseph Mercola - Take Control of Your Health

Play Episode Listen Later Jul 9, 2025 8:58


Story at-a-glance PPI heartburn drugs have been linked to a 16% higher risk of heart attacks and double the risk of dying from cardiovascular events, even in people with no history of heart disease Contrary to common belief, most reflux is caused by too little stomach acid, not too much, and PPIs worsen this problem by further suppressing acid production Long-term PPI use damages kidneys, weakens bones, impairs nutrient absorption and increases infection risk, as stomach acid is essential for pathogen defense If you're using PPIs, taper off slowly and switch to famotidine (Pepcid), a safer option that not only avoids heart risks but also helps block excess serotonin that disrupts energy and drives inflammation Full recovery of stomach acid production and digestive function after long-term PPI use takes several months up to two years, requiring targeted nutritional support

Happy Bones, Happy Life
Is Low Stomach Acid Weakening Your Bones? with Andrea Nakayama and Margie Bissinger

Happy Bones, Happy Life

Play Episode Listen Later Jul 8, 2025 39:32


Did you know that low stomach acid could be silently harming your bones? In this episode, I'm joined by Andrea Nakayama, a functional medicine nutritionist, who dives deep into the surprising connection between stomach acid and osteoporosis. We discuss why so many people with osteoporosis have low stomach acid and don't even know it, and how proton pump inhibitors (PPIs), commonly used to treat heartburn, may be making the problem worse. Andrea explains how stomach acid plays a vital role in absorbing key nutrients essential for bone health, such as calcium, magnesium, and vitamin B12, and how a lack of stomach acid can prevent the body from fully utilizing these nutrients. She also shares practical tips on how to increase stomach acid naturally and how to address heartburn without relying on harmful medications. If you're struggling with bone health or heartburn, this episode offers valuable insights into supporting your digestion and bone strength. “I always wanna remind people: Do what you can do to support your body, really take care of yourself first, and then raise your hand when you need extra help, when you can't figure it out." ~ Andrea Nakayama, FNLP MSN CNC CNE CHHC   In this episode: - [02:23] - The reason we're discussing stomach acid  - [06:12] - Low stomach acid and osteoporosis connection - [08:18] - Why it's important to have enough stomach acid - [15:44] - Heartburn: a symptom of too little stomach acid - [18:50] - Essential nutrients that impact stomach acid levels - [25:26] - PPIs: How they reduce stomach acid and increase bone loss - [27:40] - Tips for tracking issues and lifestyle strategies to aid digestion - [36:00] - Long-term effects of low stomach acid on health   Resources mentioned - Andrea's contact information - https://www.andreanakayama.com/ and https://www.fxnutrition.com/ - Osteoporosis Exercises Handout - tinyurl.com/osteoporosisexercises   More about Margie - Website - https://margiebissinger.com/  - Facebook - https://www.facebook.com/p/Margie-Bissinger-MS-PT-CHC-100063542905332/  - Instagram - https://www.instagram.com/margiebissinger/?hl=en    DISCLAIMER – The information presented on this podcast should not be construed as medical advice. It is not intended to replace consultation with your physician or healthcare provider. The ideas shared on this podcast are the expressed opinions of the guests and do not always reflect those of Margie Bissinger and Happy Bones, Happy Life Podcast.   *In compliance with the FTC guidelines, please assume the following about links on this site: Some of the links going to products are affiliate links of which I receive a small commission from sales of certain items, but the price is the same for you (sometimes, I even get to share a unique discount with you). If I post an affiliate link to a product, it is something that I personally use, support, and would recommend. I personally vet each and every product. My first priority is providing valuable information and resources to help you create positive changes in your health and bring more happiness into your life. I will only ever link to products or resources (affiliate or otherwise) that fit within this purpose.

BiketourGlobal
BTG Podcast S2/#139: Käppis & Liebe: Taunus Bikepacking mit Marina & Lukas

BiketourGlobal

Play Episode Listen Later Jul 4, 2025 104:16


Herzlich Willkommen zur 139. Ausgabe des BiketourGlobal Podcast Season 2!Das Taunus Bikepacking Event gilt seit Jahren als Geheimtipp, auch und vor allem wegen der Community und der immer wieder großartigen Strecke. Ich spreche mit Marina und Lukas über ihre Fahrt durch den Taunus und was sie daran so begeistert hat. Viel Spaß!ShownotesMarina auf Instagram https://www.instagram.com/runningmarina/Lukas auf Instagram https://www.instagram.com/bikepacking_luke/Taunus Bikepacking auf Instagram https://www.instagram.com/taunusbikepacking/Quelle MusikTropic Fuse - French Fuse aus dem YT Creator StudioQuelle Bilder Marina & Lukas

Real Talk: Eosinophilic Diseases
Bone Mineral Density in Pediatric Eosinophilic Esophagitis

Real Talk: Eosinophilic Diseases

Play Episode Listen Later Jun 24, 2025 33:16


Description: Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Sciences Advisory Council, interview Anna Henderson, MD, a pediatric gastroenterologist at Northern Light Health in Maine, about bone mineral density in EoE patients. They discuss a paper she co-authored on the subject. Disclaimer: The information provided in this podcast is designed to support, not replace, the relationship that exists between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own.   Key Takeaways: [:50] Co-host Ryan Piansky introduces the episode, brought to you thanks to the support of Education Partners Bristol Myers Squibb, Sanofi, Regeneron, and Takeda. Ryan introduces co-host Holly Knotowicz.   [1:17] Holly introduces today's topic, eosinophilic esophagitis (EoE), and bone density.   [1:22] Holly introduces today's guest, Dr. Anna Henderson, a pediatric gastroenterologist at Northern Light Health in Maine.   [1:29] During her pediatric and pediatric gastroenterology training at Cincinnati Children's Hospital, she took a special interest in eosinophilic esophagitis. In 2019, Dr. Henderson received APFED's NASPGHAN Outstanding EGID Abstract Award.   [1:45] Holly, a feeding therapist in Maine, has referred many patients to Dr. Henderson and is excited to have her on the show.   [2:29] Dr. Henderson is a wife and mother. She loves to swim and loves the outdoors. She practices general pediatric GI in Bangor, Maine, at a community-based academic center.   [2:52] Her patient population is the northern two-thirds of Maine. Dr. Henderson feels it is rewarding to bring her expertise from Cincinnati to a community that may not otherwise have access to specialized care.   [3:13] Dr. Henderson's interest in EoE grew as a GI fellow at Cincinnati Children's. Her research focused on biomarkers for disease response to dietary therapies and EoE's relationship to bone health.   [3:36] As a fellow, Dr. Henderson rotated through different specialized clinics. She saw there were many unanswered questions about the disease process, areas to improve treatment options, and quality of life for the patients suffering from these diseases.   [4:00] Dr. Henderson saw many patients going through endoscopies. She saw the social barriers for patients following strict diets. She saw a huge need in EoE and jumped on it.   [4:20] Ryan grew up with EoE. He remembers the struggles of constant scopes, different treatment options, and dietary therapy. Many people struggled to find what was best for them before there was a good approved treatment.   [4:38] As part of Ryan's journey, he learned he has osteoporosis. He was diagnosed at age 18 or 19. His DEXA scan had such a low Z-score that they thought the machine was broken. He was retested.   [5:12] Dr. Henderson explains that bone mineral density is a key measure of bone health and strength. Denser bones contain more minerals and are stronger. A low bone mineral density means weaker bones. Weaker bones increase the risk of fracture.   [5:36] DEXA scan stands for Dual Energy X-ray Absorptiometry scan. It's a type of X-ray that takes 10 to 30 minutes. A machine scans over their bones. Typically, we're most interested in the lumbar spine and hip bones.   [5:56] The results are standardized to the patient's height and weight, with 0 being the average. A negative number means weaker bones than average for that patient's height and weight. Anything positive means stronger bones for that patient's height and weight.   [6:34] A lot of things can affect a patient's bone mineral density: genetics, dietary history, calcium and Vitamin D intake, and medications, including steroid use. Prednisone is a big risk factor for bone disease.   [7:07] Other risk factors are medical and auto-immune conditions, like celiac disease, and age. Any patient will have their highest bone density in their 20s to 30s. Females typically have lower bone mineral density than males.   [7:26] The last factor is lifestyle. Patients who are more active and do weight-bearing exercises will have higher bone mineral density than patients who have more of a sedentary lifestyle.   [7:56] Ryan was told his bone mineral density issues were probably a side-effect of the long-term steroids he was on for his EoE. Ryan is now on benralizumab for eosinophilic asthma. He is off steroids.   [8:36] Dr. Henderson says the research is needed to find causes of bone mineral density loss besides glucocorticoids.   [8:45] EoE patients are on swallowed steroids, fluticasone, budesonide, etc. Other patients are on steroids for asthma, eczema, and allergic rhinitis. These may be intranasal steroids or topical steroids.   [9:01] Dr. Henderson says we wondered whether or not all of those steroids and those combined risks put the EoE population at risk for low bone mineral density. There's not a lot published in that area.   [9:14] We know that proton pump inhibitors can increase the risk of low bone mineral density. A lot of EoE patients are on proton pump inhibitors.   [9:23] That was where Dr. Henderson's interest started. She didn't have a great way to screen for bone mineral density issues or even know if it was a problem in her patients more than was expected in a typical patient population.   [9:57] Holly wasn't diagnosed with EoE until she was in her late 20s. She was undiagnosed but was given prednisone for her problems. Now she wonders if she should get a DEXA scan.   [10:15] Holly hopes the listeners will learn something and advocate for themselves or for their children.   [10:52] If a patient is concerned about their bone mineral density, talking to your PCP is a perfect place to start. They can discuss the risk factors and order a DEXA scan and interpret it, if needed.   [11:11] If osteoporosis is diagnosed, you should see an endocrinologist, specifically to discuss therapy, including medications called bisphosphonates.   [11:36] From an EoE perspective, patients can talk to their gastroenterologist about what bone mineral density risk factors may be and if multiple risk factors exist. Gastroenterologists are also more than capable of ordering DEXA scans and helping their patients along that journey.   [11:53] A DEXA scan is typically the way to measure bone mineral density. It's low radiation, it's easy, it's fast, and relatively inexpensive.   [12:10] It's also useful in following up over time in response to different interventions, whether or not that's stopping medications or starting medications.   [12:30] Dr. Henderson co-authored a paper in the Journal of Pediatric Gastroenterology and Nutrition, called “Prevalence and Predictors of Compromised Bone Mineral Density in Pediatric Eosinophilic Esophagitis.” The study looked at potential variables.   [12:59] The researchers were looking at chronic systemic steroid use. They thought it was an issue in their patients, especially patients with multiple atopic diseases like asthma, eczema, and allergic rhinitis. That's where the study started.   [13:22] Over the years, proton pump inhibitors have become more ubiquitous, and more research has come out. The study tried to find out if this was an issue or not. There weren't any guidelines for following these patients, as it was a retrospective study.    [13:42] At the time, Dr. Henderson was at a large institution with a huge EoE population. She saw that she could do a study and gather a lot of information on a large population of patients. Studies like this are the start of figuring out the guidelines for the future.   [14:34] Dr. Henderson wanted to determine whether pediatric patients with EoE had a lower-than-expected bone mineral density, compared to their peers. [14:44] Then, if there were deficits, she wanted to determine where they were more pronounced. Were they more pronounced in certain subgroups of patients with EoE?   [14:59] Were they patients with an elemental diet? Patients with an elimination diet? Were they patients on steroids or PPIs? Were they patients with multiple atopic diseases? Is low bone mineral density just a manifestation of their disease processes?   [15:14] Do patients with active EoE have a greater propensity to have low bone mineral density? The study was diving into see what the potential risk factors are for this patient population.   [15:45] The study was a retrospective chart review. They looked at patients aged 3 to 21. You can't do a DEXA scan on a younger patient, and 21 is when people leave pediatrics.   [16:03] These were all patients who had the diagnosis of EoE and were seen at Cincinnati Children's in the period between 2014 and 2017. That period enabled full ability for chart review. Then they looked at the patients who had DEXA scans.   [16:20] They did a manual chart review of all of the patients and tried to tease out what the potential exposures were. They looked at demographics, age, sex, the age of the diagnosis of EoE, medications used, such as PPIs, and all different swallowed steroids.   [16:44] They got as complete a dietary history as they could: whether or not patients were on an elemental diet, whether that was a full elemental diet, whether they were on a five-food, six-food, or cow's milk elimination diet.   [16:58] They teased out as much as they could. One of the limitations of a retrospective chart review is that you can't get some of the details, compared to doing a prospective study. For example, they couldn't tease out the dosing or length of therapy, as they would have liked.   [17:19] They classified those exposures as whether or not the patient was ever exposed to those medications, whether or not they were taking them at the time of the DEXA scan, or if they had been exposed within the year before the DEXA scan.   [17:40] They also looked at whether the patients had other comorbid atopic disorders, to see if those played a role, as well.   [18:03] The study found that there was a slightly lower-than-expected bone mineral density in the patients. The score was -0.55, lower than average but not diagnostic of a low bone mineral density, which would be -2 or below.   [18:27] There were 23 patients with low bone mineral density scores of -2 or below. That was 8.6% of the study patients. Typically, only 2.5% of the population would have that score. It was hard to tease out the specific risk factors in a small population of 23.   [18:57] They looked at what the specific risk factors were that were associated with low bone mineral density, or bone mineral density in general.   [19:12] After moving from Colorado, Holly has transferred to a new care team, and doctors wanted her baseline Vitamin D and Calcium levels. No one had ever tested that on her before. Dr. Henderson says it's hard because there's nothing published on what to do.   [19:58] The biggest surprise in the study was that swallowed steroids, or even combined steroid exposure, didn't have any effect on bone mineral density. That was reassuring, in light of what is known about glucocorticoid use.   [20:16] The impact of PPI use was interesting. The study found that any lifetime use of PPIs did seem to decrease bone mineral density. It was difficult to tease out the dosing and the time that a patient was on PPIs.   [20:34] Dr. Henderson thinks that any lifetime use of PPIs is more of a representation of their cumulative use of PPIs. At the time of the study, from 2014 to 2017, PPIs were still very much first-line therapy for EoE; 97% of the study patients had taken PPIs at some time.   [21:02] There are so many more options now for therapy when a patient has a new diagnosis of EoE, especially with dupilumab now being an option.   [21:11] Dr. Henderson speaks of patients who started on PPIs and have stayed on them for years. This study allows her to question whether we need to continue patients on PPIs. When do we discuss weaning patients off PPIs, if appropriate?   [22:05] Ryan says these podcasts are a great opportunity for the community at large and also for the hosts. He just wrote himself a note to ask his endocrinologist about coming off PPIs.   [22:43] Dr. Henderson says that glucocorticoid use is a known risk factor for low bone mineral density and osteoporosis. In the asthma population, inhaled steroids can slightly decrease someone's growth potential while the patient is taking them.   [23:10] From those two facts, it was thought that swallowed steroids would have a similar effect. But since they're swallowed and not systemic, maybe things are different.   [23:23] It was reassuring to Dr. Henderson that what her study found was that the swallowed steroid didn't affect bone mineral density. There was one other study that found that swallowed steroids for EoE did not affect someone's height.   [23:51] Dr. Henderson clarifies that glucocorticoids include systemic steroids like prednisone and hydrocortisone.     [23:57] Based on Dr. Henderson's retrospective study, fluticasone as a swallowed steroid did not affect bone mineral density. It was hard to tease out the dosing, but the cumulative use did not seem to result in a deficit for bone mineral density.   [24:16] Holly shared that when she tells a family of a child she works with that the child's gastroenterologist will likely recommend steroids, she will now give them the two papers Dr. Henderson mentioned. There are different types of steroids. The average person doesn't know the difference.   [25:15] Dr. Henderson thinks that for patients who have multiple risk factors for low bone mineral density, it is reasonable to have a conversation about bone health with their gastroenterologist to see whether or not a DEXA scan would be worth it.   [25:56] If low bone mineral density is found, that needs to be followed up on.   [26:03] There are no great guidelines, but this study is a good start on what these potential risk factors are. We need some more prospective studies to look at these risk factors in more detail than Dr. Henderson's team teased out in this retrospective study.   [26:23] Dr. Henderson tells how important it is for patients to participate in prospective longitudinal studies for developing future guidelines.   [26:34] Holly points out that a lot of patients are on restrictive diets. It's important to think about the whole picture if you are starting a medication or an elimination, or a restricted diet. You have to think about the impact on your body, overall.   [27:11] People don't think of dietary therapy as medication, but it has risks and benefits involved, like a medication.   [27:50] Dr. Henderson says, in general, lifestyle management is the best strategy for managing bone health. Stay as active as you can with weight-bearing exercises and eating a well-balanced diet. If you are on a restrictive diet, make sure it's well-balanced.   [28:12] Dr. Henderson says a lot of our patients have feeding disorders, so they see feeding specialists like Holly. A balanced diet is hard when kids are very selective in their eating habits.   [29:10] Dr. Henderson says calcium and Vitamin D are the first steps in how we treat patients with low bone mineral density. A patient who is struggling with osteoporosis needs to discuss it with their endocrinologist for medications beyond supplementation.   [29:31] Ryan reminds listeners who are patients always to consult with their medical team. Don't go changing anything up just because of what we're talking about here. Ask your care team some good questions.   [29:47] Dr. Henderson would like families to be aware, first, that some patients with EoE will have bone mineral density loss, especially if they are on PPIs and restrictive diets. They should start having those discussions with their providers.   [30:04] Second, Dr. Henderson would like families to be reassured that swallowed steroids and combined steroid exposure didn't have an impact on bone mineral density. Everyone can take that away from today's chat.   [30:18] Lastly, Dr. Henderson gives another plug for patient participation in prospective studies, if they're presented with the opportunity. It's super important to be able to gather more information and make guidelines better for our patients. [30:35] Holly thanks Dr. Henderson for coming on Real Talk — Eosinophilic Diseases and sharing her insights on bone mineral density, and supporting patients in Maine.   [30:57] Dr. Henderson will continue to focus on the clinical side. She loves doing outreach clinics in rural Maine. It's rewarding, getting to meet all of these patients and taking care of patients who would otherwise have to travel hours to see a provider.   [32:01] Ryan thinks the listeners got a lot out of this. For our listeners who would like to learn more about eosinophilic disorders, please visit APFED.org and check out the links in the show notes.   [32:11] If you're looking to find specialists who treat eosinophilic disorders, we encourage you to use APFED's Specialist Finder at APFED.org/specialist.   [32:19] If you'd like to connect with others impacted by eosinophilic diseases, please join APFED's online community on the Inspire Network at APFED.org/connections.   [32:28] Ryan thanks Dr. Henderson for joining us today for this great conversation. Holly also thanks APFED's Education Partners Bristol Myers Squibb, Sanofi, Regeneron, and Takeda for supporting this episode.   Mentioned in This Episode: Anna Henderson, MD, a pediatric gastroenterologist at Northern Light Health in Maine Cincinnati Children's “Prevalence and Predictors of Compromised Bone Mineral Density in Pediatric Eosinophilic Esophagitis.” Journal of Pediatric Gastroenterology and Nutrition   APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast apfed.org/specialist apfed.org/connections   Education Partners: This episode of APFED's podcast is brought to you thanks to the support of Bristol Myers Squibb, Sanofi, Regeneron, and Takeda.   Tweetables:   “DEXA scan stands for dual-energy X-ray absorptiometry scan. It's a type of X-ray where a patient lies down for 10 to 30 minutes. A machine scans over their bones. Typically, we're most interested in the lumbar spine and hip bones.” — Anna Henderson, MD   “We wondered whether or not all of those steroids and those combined risks even put our EoE population at risk for low bone mineral density. There's not a lot published in that area.” — Anna Henderson, MD   “If a patient is worried [about their bone mineral density], their PCP is a perfect place to start for that. They're more than capable of discussing the risk factors specific for that patient, ordering a DEXA scan, and interpreting it if need be.” — Anna Henderson, MD   “I think we need some more prospective studies to look at these risk factors in a little bit more detail than we were able to tease out in our retrospective review.” — Anna Henderson, MD   “Just another plug for the participation in prospective studies, if you're presented with the opportunity. It's super important to be able to gather more information and to be able to make guidelines better for our patients about these risks.” — Anna Henderson, MD

Swallow Your Pride
372 – What If Reflux Isn’t Just an Acid Problem? A New Way to Think About It with RefluxRaft

Swallow Your Pride

Play Episode Listen Later Jun 19, 2025 39:44 Transcription Available


What do you get when you mix a surgeon, a scientist, and a self-proclaimed “tinkerer” who also happens to struggle with reflux? You get Dr. James Daniero—and you get this conversation about RefluxRaft. In this episode, Theresa Richard chats with Dr. Daniero, an ENT who's not just treating voice, airway, and swallowing disorders—he's innovating them. From basement experiments to biomaterials backed by NIH grants, Dr. Daniero walks us through how his personal journey with reflux turned into RefluxRaft, a barrier-based solution designed to help patients (and clinicians) think beyond PPIs. We dive into the science behind alginates, the "physics problem" behind reflux, and the collaborative power between ENTs, SLPs, and GIs. This one's for the med SLPs who want to understand the why behind the symptoms—and the potential tools to help. https://RefluxRaft.com Download show notes and references here: https://syppodcast.com/372 The post 372 – What If Reflux Isn't Just an Acid Problem? A New Way to Think About It with RefluxRaft appeared first on Swallow Your Pride Podcast.

Dr. Joseph Mercola - Take Control of Your Health
The Truth About Acid Drugs: Why Pepcid Outperforms the Rest - AI Podcast

Dr. Joseph Mercola - Take Control of Your Health

Play Episode Listen Later Jun 12, 2025 9:27


Story at-a-glance Pepcid (famotidine) uniquely blocks serotonin activity unlike other H2 blockers, helping interrupt chronic pain, inflammation and fatigue caused by elevated serotonin levels A 70-year-old patient's life-threatening serotonin syndrome was rapidly reversed within 15 minutes using intravenous famotidine, demonstrating its powerful anti-serotonin effects Elevated serotonin impairs mitochondrial energy production and drives chronic inflammation, depression and pain, contrary to the popular "feel-good chemical" misconception Pepcid is safer than recalled Zantac (ranitidine) and more potent than older H2 blockers, with fewer drug interactions and decades of proven safety Unlike proton pump inhibitors (PPIs) with serious long-term risks, Pepcid offers a safer approach by targeting serotonin overload while providing effective heartburn relief

The Autoimmune RESET
How Scleroderma Impacts Gut Health — And What You Can Do About It

The Autoimmune RESET

Play Episode Listen Later Jun 8, 2025 31:40


Send us a textGut issues are incredibly common in scleroderma — but they also show up across many autoimmune diseases. In this episode, I'm diving deep into how scleroderma affects the gut, why gut motility and vagal tone matter so much, and what you can actually do to support digestion and resilience — whether or not you have a scleroderma diagnosis.If you're dealing with bloating, reflux, constipation, food sensitivities, SIBO, or nutrient deficiencies — this one is for you.I'll cover:How excess collagen and nervous system changes affect gut functionWhy so many people end up on PPIs — and what to do alongside themHow to safely support motility and nutrient absorptionMy go-to foods and supplements for gut repair and resilienceThe critical role of vagal tone — and simple ways to improve itPractical steps to address stubborn constipationPlus I'll share how I use Nurosym for vagus nerve support (discount code VH5 for 5% off here), and how our Gut Health Testing Package can help you get to the root of your gut symptoms. Learn more here. And don't miss our upcoming live Q&A on Foods to Eat for Autoimmune Disease inside The Autoimmune Forum — happening 18th June. Link in show notes.Your gut can heal — and this episode will give you the tools to start.Thanks for listening! You can join The Autoimmune Forum on Facebook or find me on Instagram @theautoimmunitynutritionist.

Rennthusiast Radio
The Porsche Market Is Full of Liars. Here's How To Avoid Getting Burned

Rennthusiast Radio

Play Episode Listen Later May 13, 2025 38:24


In this episode of Renthusiast Radio, Will and Derek crack open the shady side of the Porsche marketplace—the half-truths, strategic omissions, and full-on scams that buyers need to watch out for. From odometer fraud and blurry listing photos to cleverly staged “cold starts” and flippers pretending they're not, they share real experiences and the psychological games sellers play to close the deal.Will reveals what finally pushed him over the edge into doing this episode—hint: it involves a mysteriously “perfect” car that showed up dripping oil. Derek adds tales of deceit, missing paperwork, and how sellers weaponize your excitement against you. But it's not just venting—they'll arm you with the best ways to protect yourself, from smarter PPIs to reading between the lines of sketchy seller stories.If you've ever bought a car remotely, been ghosted after asking tough questions, or heard “I've got a guy flying in tomorrow,” this one's for you.Enjoying the show? Don't forget to:Subscribe to the Renthusiast YouTube channel for Porsche deep dives, ownership stories, and more.Check out Derek's channel ElevenAfterNine for raw sound tests, driving reviews, and real-world Porsche content.Drop your wildest seller horror stories in the YouTube comments—we might read yours in a future episode!And remember: Buy the seller, not just the car. Hosted on Acast. See acast.com/privacy for more information.

Ohrenbär Podcast | Ohrenbär
Feuerwehrschnecke Pam (2/7): Püppis Nest

Ohrenbär Podcast | Ohrenbär

Play Episode Listen Later May 12, 2025 9:22


Obwohl Pam sich sofort auf den Weg gemacht hat, kommt die Feuerwehrschnecke zu spät zum Brand. Er ist gelöscht. Aber es gibt ein anderes Problem: Püppis Nest! Kann Pam helfen? Aus der OHRENBÄR-Hörgeschichte: Feuerwehrschnecke Pam (Folge 2 von 7) von Ariane Grundies. Es liest: Antje von der Ahe. ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Real Talk: Eosinophilic Diseases
Comparing Pediatric and Adult EoE

Real Talk: Eosinophilic Diseases

Play Episode Listen Later Apr 30, 2025 39:29


Description: Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Sciences Advisory Council, interview Dr. Melanie Ruffner, an Attending Physician with the Division of Allergy and Immunology and the Center for Pediatric Eosinophilic Disorders at Children's Hospital of Philadelphia. Dr. Ruffner describes her work in clinic and the paper she co-authored about pediatric and adult eosinophilic esophagitis (EoE). She covers the questions they considered in the paper and the conclusions they reached. Disclaimer: The information provided in this podcast is designed to support, not replace the relationship that exists between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own.   Key Takeaways: [:49] Co-host Ryan Piansky introduces the episode, brought to you thanks to the support of Education Partners Bristol Myers Squibb, GSK, Sanofi, Regeneron, and Takeda. Ryan introduces co-host Holly Knotowicz.   [1:17] Holly introduces today's topic, pediatric and adult eosinophilic esophagitis (EoE), and introduces today's guest, Dr. Melanie Ruffner.   [1:23] Dr. Melanie Ruffner is an attending physician with the Division of Allergy and Immunology in the Center for Pediatric Eosinophilic Disorders at Children's Hospital of Philadelphia. Holly welcomes Dr. Ruffner to Real Talk.   [1:50] As an attending physician in the Center for Pediatric Eosinophilic Disorders at Children's Hospital of Philadelphia, Dr. Ruffner sees patients who have eosinophilic esophagitis and other eosinophilic disorders, including eosinophilic GI tract disorders.   [2:09] Dr. Ruffner also leads a research group that studies how the immune system causes inflammation in response to certain foods, leading to EoE.   [2:20] Inflammation in the esophagus is tied to other diseases like epithelial barrier dysfunction and fibrosis.   [2:28] Our bodies use many different proteins that allow cells to communicate with one another. One type of signaling protein that causes inflammation is called cytokines.   [2:41] Dr. Ruffner's group is interested in how these signaling proteins called cytokines interact with epithelial cells and how that impacts the oral function of the esophagus in patients with EoE.   [3:02] In training, Dr. Ruffner became interested in eosinophilic esophagitis and other non-IgE-mediated food allergies because we don't have a lot of clear treatments or clear mechanisms that cause them.   [3:21] Dr. Ruffner felt there was a lot of work to be done in that area. It was rewarding to be in clinical encounters with those patients. Often, patients had spent a long time trying to find out what was happening and to find a treatment plan that worked for them.   [4:31] Dr. Ruffner's group sees some patients who have eosinophilic gastroenteritis and patients who are referred for hypereosinophilia with impacts of inflammation in other organ systems.   [5:06] Dr. Ruffner co-authored a paper about pediatric and adult EoE published in the Journal of Allergy and Clinical Immunology. It explored if EoE in pediatric patients and adult patients is a spectrum or distinct diseases.   [5:29] EoE is a chronic allergic condition that affects the esophagus. The esophagus carries food from the mouth to the stomach. In people with EoE, the immune system overreacts to foods and causes inflammation in the esophagus.   [5:47] Eosinophils are a type of white blood cell. Eosinophils infiltrate the tissue in the esophagus of people with EoE. Doctors look for eosinophils in the tissue of the esophagus as a sign that inflammation in the esophagus is EoE.   [6:04] The symptoms of EoE can vary in children and adults. That was one of the things the doctors were interested in when they were thinking about this paper. There are no blood or allergy tests that make it easy to diagnose EoE, which requires an endoscopy.   [6:31] An endoscopy is performed by a gastroenterologist. The gastroenterologists look at the appearance of the esophagus and take biopsies.   [6:49] A pathologist counts the eosinophils in the tissue to determine if there are eosinophils present. If there are more than 15 eosinophils in the high-powered field of the microscope and symptoms and clinical conditions are present, EoE is diagnosed.   [7:25] One of the variables Dr. Ruffner considers is that symptoms can be different in children versus adults. In older adolescents and adults, the classic symptom is difficulty swallowing or dysphagia. That is often caused by fibrosis in the esophagus.   [7:54] In younger children this is often not how EoE presents. They may vomit or refuse food. They may experience more weight loss. Symptoms vary over the lifespan. Pediatric EoE symptoms of nausea and abdominal pain can also show up in adults.   [9:54] Atopy refers to allergic conditions. In the paper, a history of atopy means a history of allergic conditions, like atopic dermatitis, IgE-mediated food allergy, allergic rhinitis, or asthma.   [10:37] These disorders tend to cluster together, over time, because they share many common genetic risks. They cluster in families because some of the genetic risks are the same. Not every family member will have the same atopic or allergic conditions.   [11:07] In families, perhaps one person will have atopic dermatitis and allergic rhinitis while another will have atopic dermatitis, allergic rhinitis, asthma, and EoE. They may have inherited different genetics or had different environmental exposures.   [11:50] Ryan says that describes his family. They each have different atopic conditions. Ryan got them all! Dr. Ruffner says it describes her family, as well.   [12:26] Dr. Ruffner says it's understandable for families to stress about atopic conditions. Unfortunately, right now, there's no way to predict who will develop which atopic conditions. It's on the minds of the medical and research communities.   [13:10] IgE is an antibody that binds to food allergens and mediates anaphylaxis, usually within 30 minutes, with hives, vomiting, and difficulty breathing. Not everyone with a diagnosed food allergy will be given an epinephrine auto-injector.   [13:44] IgE-mediated food allergies are influenced by type 2 cytokines. Cytokines are immune system signaling proteins that have been labeled as groups. The group that is involved in allergy most heavily is under the label type 2.   [14:15] These type 2 cytokines are responsible for influencing B cells to make IgE. In the tissue in EoE, we find that there is a large amount of these type 2 cytokines present.   [14:37] This is quite relevant because dupilumab, the monoclonal antibody that has been approved to treat EoE, targets type 2 inflammation by blocking type 2 cytokines.   [16:04] Dr. Ruffner says one of the biggest challenges in the field of EoE is we don't have a way to stratify who should get which treatment for EoE. Patients have to choose between diet and pharmacologic therapy.   [16:48] We don't know enough about the inflammatory profiles to give any patient the specific guided information that one therapy would be better than another.   [17:11] Pediatric and adult patients are given the same treatment options. Some dosing, such as proton pump inhibitors and dupilumab, is weight-based so different doses are needed.   [17:36] Over time, people's needs change. From early school age to when people leave home, they may have very different needs. They may do well on diet therapy when their diet is controlled by parents, but, on their own, that may not be the best option for them.   [18:20] Therapy may change over time to support each patient's individual goals. It can be challenging because therapies are imperfect. Each therapy has a percentage probability of success. Not every therapy is guaranteed to work for every individual.   [19:01] There is some flexibility and possibility of switching between therapies to support people. Ryan shares one of his experiences in changing treatments.   [20:03] Some patients are stable on a therapy for a time but then see symptoms creep back up. Dr. Ruffner strongly suggests they talk to their care team for an endoscopy and biopsy to see if they need to switch therapy and if their diet has changed.   [21:31] In young children, Dr. Ruffner sees a much higher incidence of feeding refusal. The child may have a preferred food or a preferred texture like puree, long past when that would be appropriate for the age.   [22:41] It can be very difficult to move past this learned behavior even if remission is achieved through therapy. The child may need feeding therapy to help with that. [22:59] Feeding behaviors in older individuals may be much more subtle. Talk about them with your care team. Needing water to eat, cutting food very small, and fearing to eat around people are common eating behaviors to discuss in older patients.   [23:53] These eating behaviors affect people's well-being deeply because they affect how social they feel when they are around people. Ideally, you want to be around people and share in social times.   [24:16] Holly has used these eating behaviors herself and notices them in other people. When adults come to her for therapy, she asks how many times they refill their water when they eat, and if food ever gets stuck. They are surprised that those are symptoms.   [26:01] Dr. Ruffner says it's important to recognize the difference in symptoms in diagnosing EoE. The main risk factor of EoE is fibrosis, over time. The thought is that early in EoE there is an inflammatory phenotype, but later, there is a fibrotic phenotype.   [26:51] The phenotype refers to the presentation or characteristic of disease. What is the appearance at endoscopy? What do we see in the biopsied tissue? Is there fibrosis or not?   [27:15] This is the crux of the paper: Is this on a spectrum, that the inflammation is driving the fibrosis, or are these two different things altogether? There is some evidence to suggest that the inflammation contributes to this fibrosis over time.   [27:40] One thing that is missing is following a group of patients from the start and having that evidence. There is mechanistic evidence from studies to show that inflammation can contribute to fibrosis. That was one of the discussions in the paper.   [28:29] In endoscopies, something that can be seen with fibrosis or fibrostenotic features is more of an appearance of rings and narrowing of the esophagus. A proportion of patients with strictures or narrowing need to have them dilated.   [29:11] For patients who have dilation, it can help with symptoms significantly. When pathologists look at the tissue with fibrosis, they can see changes in the protein structure. There is more collagen and other changes in the tissue, causing fibrosis.   [30:03] Some patients use adaptive eating behaviors to adapt to significant changes in their esophagus and go for many years without being diagnosed until they present with an impaction when food becomes stuck in their esophagus.   [30:46] This makes EoE a challenging disorder for many because it can be very difficult to diagnose. The journey to a diagnosis is very individual. As a group, adults are much more likely to have fibrosis, leading to dysphagia, strictures, or impaction.   [31:25] Statistically, across all patients, you see fibrosis more in adults than in children.   [32:42] In the paper, Th1 cells are mentioned. Th1 is an immune system term referring to a cell that produces interferon-gamma. Studies show there may be differences in interferon signaling in different age groups but it needs to be studied further.   [33:57] Dr. Ruffner's team had looked at a small group and saw that interferon signaling seemed to be relatively similar between children and adults. Both CD4 and CD8 T cells (types of immune system cells) are potentially producing interferon in the esophagus.   [34:32] More study needs to be done around those immune system cells and their potential significance in EoE, if any.   [35:33] The paper suggests that EoE in children and adults is essentially a spectrum of the same disorder rather than distinct diseases.   [35:42] Aspects of immunology, responses to different treatments across children and adults, the similar responses to diet and different medications, and over time in the same individuals, indicate these are changes and complications over time.   [36:41] Dr. Ruffner suggests that medical researchers need to understand which patients are at the highest risk of complications and work to identify the best treatments to prevent those.   [37:14] Dr. Ruffner is thinking about the response to proton pump inhibitor therapy. One of the things she is looking at is whether or not proton pump inhibitors affect how eosinophils migrate into the tissue.   [37:33] They are finding that it seems that PPIs can decrease the degree of migration of eosinophils into the tissue. They are very interested in looking at that. Ryan says when Dr. Ruffner gets that paper published, she'll have to come back on the show!   [38:06] Ryan thanks Dr. Ruffner. For our listeners who would like to learn more about eosinophilic disorders, including EoE, please visit APFED.org and check out the links in the show notes.   [38:15] If you're looking to find a specialist who treats eosinophilic disorders, we encourage you to use APFED's Specialist Finder at APFED.org/specialist.   [38:24] If you'd like to connect with others impacted by eosinophilic diseases, please join APFED's online community on the Inspire Network at APFED.org/connections.   [38:33] Ryan thanks Dr. Ruffner for participating in the podcast episode. Holly also thanks APFED's Education Partners Bristol Myers Squibb, GSK, Sanofi, Regeneron, and Takeda for supporting this episode.   Mentioned in This Episode: Dr. Melanie Ruffner, MD, PhD, Attending Physician with the Division of Allergy and Immunology and the Center for Pediatric Eosinophilic Disorders at Children's Hospital of Philadelphia “Pediatric and adult EoE: A spectrum or distinct diseases?” by Stanislaw J. Gabryszewski, Melanie A. Ruffner, and Jonathan M. Spergel   APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast apfed.org/specialist apfed.org/connections   Education Partners: This episode of APFED's podcast is brought to you thanks to the support of Bristol Myers Squibb, GSK, Sanofi, Regeneron, and Takeda.   Tweetables:   “EoE is a chronic allergic condition that affects the esophagus. The esophagus carries food from the mouth to the stomach. In people with EoE, the immune system overreacts to food allergens and causes inflammation in the esophagus.” — Dr. Melanie Ruffner   “In EoE, there are no blood or allergy tests that make it easy to diagnose EoE without an endoscopy.” — Dr. Melanie Ruffner   “Is EoE on a spectrum, that the inflammation is driving the fibrosis, or are these two different things altogether? There is some evidence to suggest that the inflammation contributes to fibrosis over time.” — Dr. Melanie Ruffner   “When pathologists look at the tissue with fibrosis, they can see the changes in the protein structure.” — Dr. Melanie Ruffner   “There are some folks who have adapted their eating behavior quite significantly and may have quite a number of chronic changes in their esophagus that they have adapted around, and they go for many years without being diagnosed.” — Dr. Melanie Ruffner

The Real GI Doc Show
The Truth About PPIs and Dementia (Part 1 of 2)

The Real GI Doc Show

Play Episode Listen Later Apr 22, 2025 44:39


In this episode of The Real GI Doc Show, Dr. Fred Gandolfo reviews current concerns surrounding heartburn drugs called proton pump inhibitors (PPIs) and their potential risks with a focus on the risk of dementia. Key discussions include: - An in-depth look at PPIs, including their mechanism of action, common uses, and the historical context of their development. - The array of misconceptions surrounding PPIs, especially concerning their association with serious side effects, including dementia risk. - A breakdown of the scientific method and how to critically evaluate research studies, illustrating the importance of understanding study design and evidence quality. - The definition of pseudoscience and how it contrasts with legitimate scientific inquiry, emphasizing the dangers of starting with conclusions rather than evidence. - The challenges of conducting long-term studies on PPIs and dementia, highlighting the need for rigorous, well-designed research. As the episode wraps up, Dr. Gandolfo emphasizes the importance of discerning credible medical information from pseudoscience and encourages listeners to engage with their healthcare providers about any concerns regarding medications. Stay tuned for part two, where Dr. Gandolfo will delve deeper into the existing studies on PPIs and dementia, providing insights on how to approach treatment decisions. Referenced in this episode: Episode 3: Stomach Acidity Episode 5: Understanding GERD: Diagnosis, Treatment, and Prevention Watch The Real GI Doc Show on YouTube! Click here! Be sure to subscribe to The Real GI Doc Show for more insights, and reach out with your questions on social media @realgidoc or leave an audio question for Dr. Gandolfo here. Find The Real GI Doc Show on social media, join the newsletter, read Dr. Gandolfo's bio, or ask a question using this link.

Nutrition with Judy
329. Should you eat fermented foods? Colonoscopies, PPIs, Antibiotics, H.Pylori – Dr. Neil Stollman

Nutrition with Judy

Play Episode Listen Later Apr 17, 2025 113:47


Support your health journey with our private practice! Explore comprehensive lab testing, functional assessments, and expert guidance for your wellness journey. Find exclusive offers for podcast listeners at nutritionwithjudy.com/podcast. _____Dr. Neil and I dive into the complexity of the gut microbiome, challenging the notion that a single probiotic strain can fix everything. We explore how diversity—not one 'superbug'—may be the real key to gut health. We also unpack how fecal transplants work, why antibiotics often do more harm than good, and if fermented foods are necessary or ideal.Dr. Neil Stollman is a practicing gastroenterologist based in Oakland, California, and serves as voluntary faculty at UCSF. A pioneer in the field of fecal microbiota transplantation (FMT), he has been involved in gut microbiome research and treatment for over two decades. Known for his work with Clostridium difficile infection (CDI) and broader gut health issues, Dr. Stollman brings a balanced and often humorous perspective to microbiome science.We discuss the following:All about Dr. Neil StollmanThe importance of gut healthAll about AkkermansiaGlyphosate and other antimicrobial foodsFMT (Fecal Microbiota Transplantation)Getting sick from C. diff (Clostridioides difficile)Strengthening the MicrobiomeDo we need FermentsThoughts on giving antibiotics to people with C. diffSymptoms of H. pyloriThoughts on long-term PPI useWhy gut doctors prescribe PPIsThoughts on colon testsWhere to find Dr. Neil Stollman_____EPISODE RESOURCESWebsiteTwitterThe Sonnenburgs Fermented Food StudyOpenBiome (Stool Bank)NwJ Complete Wellness PanelComplete GI Map Stool Test_____WEEKLY NEWSLETTER 

Dr. Ruscio Radio: Health, Nutrition and Functional Medicine
962 - 6 Overlooked Causes of Heartburn (GERD) And How to Treat

Dr. Ruscio Radio: Health, Nutrition and Functional Medicine

Play Episode Listen Later Apr 14, 2025 49:08


In this episode, I'll cover the root causes of reflux & share the most effective treatments. Tune in! Work with us! https://drruscio.com/virtual-clinic/ Product mentions:  Thiamega https://www.objectivenutrients.com/products/thiamega/ Vagustim https://vagustim.io/   Watch next

Performance Medicine Audio
The Problem With PPIs | Explain This Ep. 114 w/ Robin Riddle, FNP-C

Performance Medicine Audio

Play Episode Listen Later Apr 11, 2025 18:23


Many people are prescribed a PPI without knowing the reasons, or how long long they should be taking it.In this episode, Robin Riddle, FNP-C breaks down the issues with PPIs, who actually needs them, and the right way to taper off.What did you think of this episode of the podcast? Let us know by leaving a review!Connect with Performance Medicine!Check out our new online vitamin store:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://performancemedicine.net/shop/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sign up for our weekly newsletter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://performancemedicine.net/doctors-note-sign-up/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@PMedicine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@PerformancemedicineTN⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Performance Medicine⁠

Primary Care Update
Episode 178: tapering benzos, neuro testing for athletes, vonoprazan for PUD, and zoster-dementia link

Primary Care Update

Play Episode Listen Later Apr 8, 2025 34:24


This week Kate, Gary, Mark and Henry discuss discontinuation of benzodiazepines and treatment of insomnia, the value of baseline cognitive testing of college athletes, vonoprazan vs PPI for preventing and treating ulcers, and whether herpes zoster vaccine reduces dementia risk.Show links:Essential Evidence Plus: www.essentialevidenceplus.comTapering benzos: https://pubmed.ncbi.nlm.nih.gov/39374004/ Baseline neuro eval for athletes: pubmed.ncbi.nlm.nih.gov/39741470/ David Kaufman, “We Need You in the Locker Room” https://thesagergroup.net/books/in-the-locker-room Vonoprazan vs PPIs for ulcers: https://pubmed.ncbi.nlm.nih.gov/39294424/ Zoster and dementia: https://pubmed.ncbi.nlm.nih.gov/40175543/ 

biobalancehealth's podcast
GLP-1 Weight Loss Medications' Biggest Side Effect

biobalancehealth's podcast

Play Episode Listen Later Apr 8, 2025 20:59


See all the Healthcasts at https://www.biobalancehealth.com/healthcast-blog The newest miracle drug for weight loss is changing the lives of thousands of people who have battled obesity for extended periods of time….These GLP-1 medications are also treating or preventing the diseases that go with long term obesity: Diabetes, Heart Disease, Joint replacements, Arthritis, Sleep Apnea, and Alzheimer's Disease. Researchers are finding more indications every day for patients to take these weight loss medications. But like anything else there is no perfect answer to any problem.  Among the few side effects of this drug, the most frequent side effect is reflux, also called acid indigestion, or GERD (gastroesophageal reflux disease).  Often my patients don't even know what their diagnosis is, they just tell me about their symptoms. The symptoms of GERD include: Asthma symptoms A bad taste in the mouth Difficulty swallowing Dry, hacking, cough Chest pain after meals These symptoms are worse after a big meal, at bedtime, after spicy food, or dose related.  Most of my patients don't want to discontinue the GLP-1 inhibitors because they are finally losing weight!  We manage the GLP-1 side effect of GERD by decreasing dose of the medication and slowly increase the dose back to an effective level. We also offer lifestyle and dietary treatments before we offer prescription medication. Therefore, if reflux is not constant, and is not causing any lasting damage to the patient's esophagus, we can treat it with lifestyle changes and over the counter medication, to lower the stomach acid that is refluxing into the esophagus. The lifestyle changes patients can employ on their own are described below. Lifestyle changes needed to avoid or treat Gastric Reflux caused by GLP-1 agonists. What can you do to prevent and treat this side effect: Eat smaller meals: Large meals expand your stomach and put pressure on your lower esophageal sphincter (LES). Don't go to bed less than 2 hours after eating Avoid trigger foods see below Sleep on your left side Elevate the head of your bed Avoid tight clothing: Chew your food well– chew each bite for 20 seconds. Quit smoking: Smoking weakens your LES and makes your stomach more acidic. Stop drinking alcohol Chew (non-mint) sugar-free–gum  In addition to changing your active lifestyle, changing your diet is necessary as well. There are trigger foods to avoid minimizing your reflux symptoms.  tomato sauce and other tomato-based products high fat foods, such as fast food and greasy foods fried foods citrus fruit juices soda-diet and regular Caffeine Garlic onions mint of any kind milk based products My patients ask me, “So what can I eat?” …I admit I did take away some of the most exciting foods, however my patients ask me what they can eat so the list of foods that help avoid and treat GERD are listed below. High-fiber foods: vegetables, fruit, and whole grain bread. Alkaline foods. Foods fall somewhere along the pH scale (turns litmus paper blue). Drink alkalinized water (PH > 8) Ginger—fresh sushi Ginger from Asian food stores. Apple cider vinegar on salads and a Tablespoon in water every morning Lemon water—just squeeze a slice of lemon in your water. Coconut water Honey. Lean Protein including meat Low-Fat and Nonfat Dairy Products. Non-Citrus Fruits like apples, pears, bananas, and melons Vegetables like broccoli, Carrots, Corn, Cucumbers, Green Beans, Green peppers, Potatoes and Sweet potatoes   For my patients who take herbal and other supplements, the following is a list of the supplements that may decrease your symptoms of GERD. Chamomile Tea Licorice Marshmallow Slippery Elm Tablets Probiotics-Mega Brand Prebiotics-Mega Digestive Enzymes Aloe Vera Juice Baking Soda Magnesium glycinate What happens when you have made all the lifestyle changes you can and have lowered your GLP-1 dose or changed to a different type of GLP-1 Agonist, and you still have GERD? As a physician I prescribe medications to help my patients treat their GERD, however most of the medications have been placed over the counter so I can recommend them to my patients, and they can buy the medication without a script. The class of medication that treats GERD include Antacids, H2 Blocker, and Proton Pump Inhibitor.  Antacids neutralize stomach acid, but they typically only work for short periods. They are generally made of calcium. This type of medication is best used prn for symptom relief.  Side effects of antacids may include constipation and diarrhea. The second option for treatment of GERD is an H2 blocker. These drugs reduce the amount of acid the stomach releases. Eg. Pepcid, Tagamet, Gaviscon. Proton pump inhibitors (PPIs): These drugs are available by prescription from a healthcare provider, and now some doses are over the counter. PPIs help reduce the amount of acid the stomach makes.  They should be used for a two-week period only for severe attacks and then you should change to an H2 blocker or antacid. WHY stop a PPI after 2 weeks?   Omeprazole is an example of a PPI.  Theses medication kill the good bacteria in your intestines, change your breath and can affect how you absorb your nutrients. If you must take them chronically to treat and prevent the progression of damage to the esophagus. What if I did everything and GERD is still a problem: If your condition is severe, your doctor may recommend a consultation with a GI doctor for an endoscope or other diagnostic procedure.  In addition, you may have to hold your GLP-1 Agonist for a period of time while you treat your esophageal inflammation. Just as in all medical issues there are many ways to treat side effects of drugs. Your provider will prescribe the medication that she or he is most comfortable with. What next? So if you have reflux and are on a GLP-1 inhibitor, you may be advised to decrease your dose or switch to Tirzepatide medication (Mounjaro, Zepbound). There are many steps you can take before you need prescribed medication. Your doctor may even change your GLP-1 agonist prescription or refer you to a GI doctor, but before this is necessary you should try the lifestyle and dietary changes that I recommend in this Blog first. This side effect of GLP-1 agonists doesn't affect every patient and can be managed as you see above, however the lifestyle changes and dietary changes can only be done by you, so the ball is in your court!

The Real GI Doc Show
Rapid Fire Q&A, Health Insurance Denies Patients in Need!

The Real GI Doc Show

Play Episode Listen Later Mar 31, 2025 40:32


Dr. Fred Gandolfo dives into a rapid-fire Q&A session, addressing a backlog of listener questions that cover a variety of gastrointestinal topics. Key highlights include: - The pros and cons of capsule endoscopy versus traditional endoscopy and colonoscopy, particularly regarding the visualization of the small intestine. - A listener who appreciates Dr. Gandolfo's detailed explanations, leading to a discussion on the balance between clarity and conciseness in patient communication. - An exploration of swallowing difficulties related to a "twisty esophagus," including potential treatments and the importance of specialized care. - A review of the safety and efficacy of the supplement Preservision for patients with chronic pancreatitis and macular degeneration. - A discussion on the challenges of managing SIBO (small intestinal bacterial overgrowth) and the low FODMAP diet, with a promise of a future deep dive into this topic. - An examination of the long-term effects of proton pump inhibitors (PPIs) and the complexities of their use in clinical practice. As the episode concludes, Dr. Gandolfo shares a rant about the frustrations of navigating insurance hurdles in patient care, particularly concerning inflammatory bowel disease treatments. His reflections shed light on the often unseen struggles healthcare providers face while advocating for their patients against insurance denials of necessary treatment. Listeners are encouraged to submit their own questions for future episodes, ensuring that the conversation continues to address the topics that matter most to them. Watch The Real GI Doc Show on YouTube! Click here! Be sure to subscribe to The Real GI Doc Show for more insights, and reach out with your questions on social media @realgidoc or leave an audio question for Dr. Gandolfo here. Find The Real GI Doc Show on social media, join the newsletter, read Dr. Gandolfo's bio, or ask a question using this link.  

The Breast Cancer Recovery Coach
#401 Magnesium & Breast Cancer Recovery - The Mineral You Can't Ignore

The Breast Cancer Recovery Coach

Play Episode Listen Later Mar 7, 2025 24:52


In this episode of Better Than Before Breast Cancer, we're talking about the crucial role of magnesium in breast cancer recovery, metabolic health, and overall well-being What You'll Learn in This Episode:✅ Why magnesium is vital for breast cancer survivors and how it supports healing✅ How chemotherapy, aromatase inhibitors, and stress can deplete magnesium levels✅ The best types of magnesium supplements (and which one is right for you!)✅ How to get enough magnesium through diet with whole, nutrient-dense foods✅ Signs of magnesium deficiency and how to test your levels✅ How magnesium impacts inflammation, bone density, and hormone balance Download Your Free Resources:

Intelligent Medicine
Intelligent Medicine Radio for March 1, Part 2: Melatonin for Skin Rejuvenation

Intelligent Medicine

Play Episode Listen Later Mar 3, 2025 42:24


CT scan accidentally reveals calcium deposits where they don't belong; Dispelling the myth that hunter-gatherers get more sleep than Westerners; Blue light exposure at night impairs sleep—but morning exposure improves it; When normal B12 levels aren't enough; NT Factor vs. urolithin A (Mitopure®️) for mitochondria; Alternatives to PPIs for Barrett's Esophagus; Topical—not oral—melatonin for skin rejuvenation. 

The Gutbliss Podcast
Reflux: Top 3 Causes - And How to Get Rid of Them Naturally

The Gutbliss Podcast

Play Episode Listen Later Feb 20, 2025 18:34 Transcription Available


More than 60 million Americans experience heartburn on a regular basis, but the recommended treatment does nothing to address the root cause - and totally messes up your digestion. The most important thing that I want you to know is that acid reflux has absolutely nothing to do with overproduction of acid. These symptoms are caused by inappropriate opening of the lower esophageal sphincter, and on today's show, I'm going to tell you about the three most common factors that cause that lower esophageal sphincter to open, and how to treat them without blocking stomach acid. We'd love to hear from you - send us a text!Thank you for being a part of our community! For the latest in digestive wellness go to https://gutbliss.com and follow us on https://www.instagram.com/gutbliss/ for more gut health info. Dr. Robynne Chutkan

Smarter Not Harder
Mold, Medications, and Mitochondrial Health (ft. Dr. John Kim) | SNH Podcast #110

Smarter Not Harder

Play Episode Listen Later Feb 12, 2025 73:39


In this episode of the Smarter Not Harder Podcast, Dr. John Kim discusses the impact of various medications on nutrient deficiency and mitochondrial dysfunction. He focuses on commonly prescribed medications such as statins, PPIs, SSRIs, and antibiotics, detailing their effects on essential nutrients like CoQ10, B vitamins, and magnesium. Dr. Kim also shares insights on the interplay between pharmaceutical and nutraceutical treatments, the importance of hormone levels, and mitochondrial health. The episode further delves into the complications of oral contraceptives, the dangers of fluoroquinolone toxicity, and the role of methylene blue and phospholipids in combating these issues. Dr. Kim rounds out the discussion with insights into managing mold toxicity and the significance of functional medicine. Join us as we delve into: + Exploring mitochondrial dysfunction caused by common drugs + The dangers of drug-induced nutrient depletion + Enhancing recovery with methylene blue and more + Mold toxicity and its hidden health impacts This episode is for you if: - You're curious about how common meds lead to nutrient deficiencies - You're keen on understanding the synergy of methylene blue & supplements - You're interested in the link between medications and mitochondrial health - You want to know how diet and lifestyle affect neurotransmitter production You can also find this episode on… YouTube: https://www.youtube.com/watch?v=8zS-1mKbrXM Find more from Dr. John Kim: Kim Wellness: https://www.kimwellness.co/ Instagram: https://www.instagram.com/john.pharmd LinkedIn: https://www.linkedin.com/in/dhjohnkimpharmd/ Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

Plant Based Briefing
990: Acid Reflux Medicine May Cause Osteoporosis by Dr. Michael Greger at NutritionFacts.org

Plant Based Briefing

Play Episode Listen Later Feb 7, 2025 7:01


Acid Reflux Medicine May Cause Osteoporosis Stomach acid–blocking proton pump inhibitor drugs—PPIs with brand names like Prilosec, Prevacid, Nexium, Protonix, and AcipHex—appear to significantly increase the risk of bone fractures. Listen to today's episode to learn about the written by Dr. Michael Greger at @NutritionFacts.org #vegan #plantbased #plantbasedbriefing #acidreflux #GERD #osteoporosis #ppi #protonpumpinhibitors #Prilosec #prevacid #Nexium #protonix #acipHex ============================ Original post: https://nutritionfacts.org/video/acid-reflux-medicine-may-cause-osteoporosis/  Related Episodes: Acid Reflux 943: How to Prevent and Treat Heartburn Without Medication https://plantbasedbriefing.libsyn.com/943-how-to-prevent-and-treat-heartburn-without-medication-according-to-gastro-docs-by-dana-hudepohl-at-forksoverknivescom 174: [Part 1] Dining by Traffic Light: Green is for Go, Red is for Stop https://plantbasedbriefing.libsyn.com/174-part-1-dining-by-traffic-light-green-is-for-go-red-is-for-stop-by-dr-michael-greger-at-nutritionfactsorg 133: Treating Reflux in Babies with Diet https://plantbasedbriefing.libsyn.com/133-treating-reflux-in-babies-with-diet-by-dr-michael-greger-at-nutritionfactsorg 90: 'Plant Based Diet Healed My Gut and Made Me a Better Doctor' and '5 Ways to Reduce Food Waste at Home' https://plantbasedbriefing.libsyn.com/90-plant-based-diet-healed-my-gut-and-made-me-a-better-doctor-and-5-ways-to-reduce-food-waste-at-home   Osteoporosis 822: Calcium and Strong Bones https://plantbasedbriefing.libsyn.com/822-calcium-and-strong-bones-by-physicians-committee-for-responsible-medicine-at-pcrmorg  760: Fall Prevention Is the Most Important Thing for Preventing Osteoporosis Bone Fractures https://plantbasedbriefing.libsyn.com/760-fall-prevention-is-the-most-important-thing-for-preventing-osteoporosis-bone-fractures-by-dr-michael-greger-at-nutritionfactsorg  695: Is a Plant-Based Diet the Best for Senior Health? https://plantbasedbriefing.libsyn.com/695-is-a-plant-based-diet-the-best-for-senior-health-by-charlotte-pointing-at-vegnewscom 612: 5 Tips To Maintain Strong Bones And Prevent Osteoporosis https://plantbasedbriefing.libsyn.com/612-5-tips-to-maintain-strong-bones-and-prevent-osteoporosis-from-switch4goodorg  489: [Part 2] Calcium for Vegans https://plantbasedbriefing.libsyn.com/489-part-2-calcium-for-vegans-by-brigitte-gemme-at-veganfamilykitchencom 488: [Part 1] Calcium for Vegans https://plantbasedbriefing.libsyn.com/488-part-1-calcium-for-vegans-by-brigitte-gemme-at-veganfamilykitchencom 340: Milk and Osteoporosis: The Calcium Myth https://plantbasedbriefing.libsyn.com/340-milk-and-osteoporosis-the-calcium-myth-by-rick-scott-at-switch4goodorg   ============================ Dr. Michael Greger is a physician, New York Times bestselling author, and internationally recognized speaker on nutrition, food safety, and public health issues. A founding member and Fellow of the American College of Lifestyle Medicine, Dr. Greger is licensed as a general practitioner specializing in clinical nutrition. He is a graduate of the Cornell University School of Agriculture and Tufts University School of Medicine. He founded NUTRITIONFACTS.ORG is a non-profit, non-commercial, science-based public service provided by Dr. Michael Greger, providing free updates on the latest in nutrition research via bite-sized videos. There are more than a thousand videos on nearly every aspect of healthy eating, with new videos and articles uploaded every day.   His latest books —How Not to Die, the How Not to Die Cookbook, and How Not to Diet — became instant New York Times Best Sellers. His two latest books, How to Survive a Pandemic and the How Not to Diet Cookbook were released in 2020.  100% of all proceeds he has ever received from his books, DVDs, and speaking engagements have always and will always be donated to charity. ============================== FOLLOW THE SHOW ON: YouTube: https://www.youtube.com/@plantbasedbriefing     Spotify: https://open.spotify.com/show/2GONW0q2EDJMzqhuwuxdCF?si=2a20c247461d4ad7 Apple Podcasts: https://podcasts.apple.com/us/podcast/plant-based-briefing/id1562925866 Your podcast app of choice: https://pod.link/1562925866 Facebook: https://www.facebook.com/PlantBasedBriefing   LinkedIn: https://www.linkedin.com/company/plant-based-briefing/   Instagram: https://www.instagram.com/plantbasedbriefing/   

The Doctor Is In Podcast
1500. PPIs & Prediabetes: Two Health Shocks You Need to Know

The Doctor Is In Podcast

Play Episode Listen Later Feb 3, 2025 28:58


At the Martin Clinic, we've come up with our own alphabet when it comes to naming vitamins. The real vitamin C is actually coffee, vitamin S is steak. The real vitamin E is exercise and it turns out that exercise is actually a better treatment for pre-diabetes than Metformin! Join Dr. Martin as he reviews this study and shares an updated article about the dangers of the long-term use of PPIs, proton pump inhibitors.  

Intelligent Medicine
Intelligent Medicine Radio for January 11, Part 2: Why 70 is the New 60

Intelligent Medicine

Play Episode Listen Later Jan 13, 2025 42:18


“Active holistic therapy” for prostate cancer with diet and fish oil helps defer need for surgery, hormone blockade, radiation; Why 70 is the new 60; Long-term harmful effects of acid-blockers; Do memory supplements pass the blood-brain barrier? Fish oil, krill oil, olive oil for cardiovascular prevention; Paxlovid aggressively promoted but overprescribed for otherwise healthy patients. 

The Turd Nerds
#55 - Eosinophilic Esophagitis - Part 1

The Turd Nerds

Play Episode Listen Later Dec 24, 2024 36:53


In this episode, the hosts discuss Eosinophilic Esophagitis (EOE), a condition that has gained recognition in recent years. They explore its symptoms, including dysphagia and food impaction, and the importance of accurate diagnosis through endoscopy and biopsies. The conversation delves into risk factors, potential triggers such as food allergies, and the role of diet in managing EOE. Treatment options are discussed, including pharmaceutical interventions like Budesonide and PPIs, as well as dietary management strategies such as elimination diets. The hosts also touch on herbal remedies and the importance of monitoring for fungal overgrowth during treatment.

Pregnancy Podcast
The Science Behind Heartburn in Pregnancy and How to Treat It

Pregnancy Podcast

Play Episode Listen Later Dec 1, 2024 29:56


Heartburn is a common symptom during pregnancy, affecting up to 80% of expecting mothers. While it can be uncomfortable, the good news is that it resolves after you have your baby. In the meantime, there are many safe and effective ways to manage heartburn during pregnancy. Discover why heartburn is more prevalent during this time and the foods and behaviors that can trigger it. Learn about evidence-based interventions for relief, ranging from dietary and lifestyle adjustments to over-the-counter and prescription medications. Explore the evidence on the safety of heartburn medicines during pregnancy, including antacids, histamine 2 (H2) blockers, and proton pump inhibitors (PPIs). Plus, hear about the fascinating evidence that may link heartburn to how much hair your baby has.     Thank you to our sponsors   VTech is the most trusted choice for baby monitors and North America's leading #1 baby monitor brand. The Vtech V-Care Over the Crib Smart Nursery Baby Monitor has every feature you could want in a monitor to keep an eye on your baby and have peace of mind that they are safely sleeping. The V-Care has built-in intelligence to alert you if your baby's face is covered or has rolled over on their stomach, full high-definition video, infrared night vision technology, and even analysis of sleep patterns and quality. The V-Care Over the Crib Smart Nursery Baby Monitor is exclusively available on Amazon.   Looking for a way to share baby photos and stay connected to family who are far away? I've got the perfect gift for you! Skylight Frame is the touchscreen digital photo frame your whole family will love. Skylight has over a million happy customers and thousands of 5-star reviews. They are confident you will love this frame and offer free 120-day returns. And now, as a special, limited-time offer for our listeners, get $20 off your purchase of a Skylight Frame when you go to SkylightFrame.com/PREGNANCYPOD.   Treat yourself or surprise your loved ones this holiday season with gifts that illuminate them with Fount Society's clean, luxurious skincare and body care. During pregnancy, you are more cautious about the ingredients in your skincare. The Fount Society Water Cream uses clean and hydrating ingredients to transform dry winter skin into a healthy, dewy complexion. Plus, it is free of parabens, and phthalates, so you get to nourish your skin without the toxins. Visit Fount Society, your one-stop shop for every skincare lover on your list, and use code PREGNANCYPOD to get an exclusive 30% off!     Read the full article and resources that accompany this episode.     Join Pregnancy Podcast Premium to access the entire back catalog, listen to all episodes ad-free, get a copy of the Your Birth Plan Book, and more.     Check out the 40 Weeks podcast to learn how your baby grows each week and what is happening in your body. Plus, get a heads up on what to expect at your prenatal appointments and a tip for dads and partners.     For more evidence-based information, visit the Pregnancy Podcast website. https://pregnancypodcast.com

Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast
Eliminate Bloating: The Ultimate Solution by Dr. Berg

Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast

Play Episode Listen Later Nov 25, 2024 7:18


Today, I'm going to tell you how to get rid of bloating. After you chew your food, it travels through the esophagus and into the stomach. The stomach is very acidic to break down proteins and kill microbes. Ninety percent of digestion occurs in the small intestine, where bile and secondary bile salts made by your microbes break down your food. The large intestine, small intestine, and pancreas release enzymes to aid digestion. Around 20% of these enzymes are made by your microbes. Bloating is caused by a problem with digestion. The type, amount, and diversity of your gut bacteria directly affect bloating. This often depends on if you've taken antibiotics and how much you've taken over time. Broad-spectrum antibiotics significantly reduce your microbes, and they do not come back! If you're missing any of your gut microbes, you'll experience bloating, gas, burping, constipation, and more. Other chemicals in the environment that mimic antibiotics can also cause a bloated belly. Glyphosate, birth control pills, steroids, anti-depression medications, PPIs, artificial sweeteners, fluoride, and statins can all contribute to bloating. So many people can not properly digest food anymore because they don't have all of their microbes in sufficient quantities. A high-quality probiotic is a great solution to bloating. Along with probiotics, consume fermented foods regularly, such as kefir, yogurt, sauerkraut, and pickles. Apple cider vinegar and kombucha can also help awaken dormant microbes by acidifying their environment. These microbes help support your bile and enzymes, helping you digest food, which takes stress off your organs. SUPER GUT BOOK LINK: https://amzn.to/4dIxTy2 L. Reuteri Strain: https://www.amazon.com/BioGaia-Osfort... **I am finding that using only ONE TBS of fiber in the recipe makes a better-quality product. How to Make It: https://drdavisinfinitehealth.com/201... https://www.culturedfoodlife.com/l-re... MICROBIOME MASTER CLASS WEBSITE: https://innercircle.drdavisinfinitehe... Yogurt Maker — https://lvnta.com/lv_lrJY1A8ZLtxmwUpYdX Yogurt Jars — https://lvnta.com/lv_qB2B90JNh0hQjaMoXk Yogurt Containers — https://lvnta.com/lv_SFt3wnanoNkBHrf0Rs

Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast
The Greatest Overlooked Nutrient in Medicine

Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast

Play Episode Listen Later Nov 1, 2024 6:00


Vitamin K2 removes calcium from your arteries and other soft tissues and puts it into the bone where it belongs. In this video, we're going to discuss the health benefits of vitamin K2 and how it can be used to clean your arteries, prevent heart attacks, and keep you healthy! Vitamin K2 deficiency can lead to soft tissue calcification, bone corrosion, osteoporosis, and cavities. You can get vitamin K2 from the diet, or you can make it from vitamin K1 in the gut. Natto (fermented soybeans) is the food with the most vitamin K2. Eel, goose liver, chicken liver, and beef liver also contain a significant amount of vitamin K2. Butter and cheese from grass-fed animals, salami, pork chops, and fermented vegetables contain small amounts of vitamin K2. Vitamin K2 can clean your arteries naturally, yet it's found in fatty foods that we've been told to avoid! Because it's a fat-soluble vitamin, you may have trouble absorbing it if you don't have a gallbladder or you have a bad liver. You need plenty of healthy microbes to convert vitamin K1 to vitamin K2. B. subtilis is the primary microbe responsible for this conversion. Only 30% of the population has this microbe in their gut because it's very easily destroyed when you consume broad-spectrum antibiotics. Without B. subtilis and vitamin K2 foods, you're at risk for developing calcification in the arteries. Antibiotics, steroids, PPIs, antacids, glyphosate from GMO foods, alcohol, junk food, liver disease, high-sugar diets, and blood thinners destroy the gut's ability to make vitamin K2. Low-fat diets can also put you at risk for a vitamin K2 deficiency. Vitamin K2 is dependent on magnesium. Together, magnesium and vitamin K2 can help clean your arteries and remove calcium deposits from your soft tissues. There are two kinds of vitamin K2: MK4 (synthetic) and MK7 (natural). Try taking 100 mcg of MK7 vitamin K2 for every 10,000 IU of vitamin D3.