Podcasts about fluoroquinolones

Episode 200: All About Ascites.     Jesica Mendoza explains the pathophysiology, diagnosis and management of ascites. Dr. Arreaza adds input about early detection and prevention of spontaneous bacterial peritonitis. Written by Jesica Mendoza, OMS IV, Western University, College of Osteopathic Medicine of the Pacific. Edits and comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.Welcome to our episode 200! It is an honor to welcome back a wonderful medical student, her name is Jesica, and she has prepared this topic, and she is excited to share this information with us. Jesica presented in June this year an episode about gestational diabetes (episode 193) and today she will talk about ascites. Jesica, please tell us who you are again. What is ascites?Ascites is the buildup of fluid in between the visceral peritoneum and the parietal peritoneum in the abdomen. This is often caused by cirrhosis of the liver due to the increased portal HTN which leads to increased nitrous oxide (NO) and prostaglandins which then causes splanchnic vasodilation and decreased effective arterial volume. The decrease in arterial volume then causes an increase in the renin–angiotensin–aldosterone system (RAAS) and antidiuretic hormone (ADH) from the renal system which leads to sodium and water retention. This then causes a net reabsorption of fluids and ascites.Evaluation of ascites.Once someone has been found to have ascites the next step will be a diagnostic paracentesis. This includes removing fluid from the peritoneal cavity in order to determine the SAAG (Serum Ascites Albumin Gradient) score. SAAG : (serum albumin) − (albumin level of ascitic fluid). The two values should be measured at the same time.This score helps determine the cause of the ascites with a score >1.1 g/dL indicating portal hypertension usually due to liver disease such as cirrhosis. A SAAG score of 250 PMNS/mL. Fluid should be sent to the lab for culture and then antibiotics should be started. IV 3rd generation cephalosporins are typically used. Fluoroquinolones are also used to prevent the recurrence of SBP.If you desire to learn more about SBP, listen to our episode 123. By the way, propranolol is a frequently used medication to prevent GI bleeding from esophageal varices in cirrhosis and also to decrease the development of ascites. It should be used in patients who have compensated cirrhosis and must be avoided in patients with refractory ascites, hypotension, renal dysfunction or active infection. So, to wrap things up we should remember that once we identify ascites with our physical exam of the patient, we should make sure to obtain a paracentesis as these results will be the main guide for our treatment. The treatment can then range from medical treatment such as spironolactone and/or loop diuretics to TIPS procedures, PleurX or even liver transplant. Always be on the lookout for SBP in patients with ascites and always remember to obtain a culture on the ascitic fluid prior to starting antibiotics. Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:Ascites, Cleveland Clinic, https://my.clevelandclinic.org/health/diseases/14792-ascites.Huang LL, Xia HH, Zhu SL. Ascitic Fluid Analysis in the Differential Diagnosis of Ascites: Focus on Cirrhotic Ascites. J Clin Transl Hepatol. 2014 Mar;2(1):58-64. doi: 10.14218/JCTH.2013.00010. Epub 2014 Mar 15. PMID: 26357618; PMCID: PMC4521252. https://pmc.ncbi.nlm.nih.gov/articles/PMC4521252/.Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.

Episode Links:Register for the Private Podcast: Toxins, Truth & Taking ControlGet on the Toxin Free in 3 Waiting ListI'm dropping this special Thursday episode because I want you to hear directly from my students why Toxin Free in 3 has changed their lives, and today's conversation with Jen might be the most powerful one yet.In this raw and real interview, I'm talking with Jenn Cicci (Beauty in the Green), an integrative health practitioner who survived two rounds of fluoroquinolone antibiotics that left her unable to walk without braces due to tendon rupture. This was a well-known side effect her doctor never warned her about! Seven years later, she still can't run and lives with permanent damage from what should have been informed consent.But here's what really got to me: Jenn told me she left my course completely fear-free after years of following practitioners on Instagram who were constantly sharing scare tactics. She said, "I left that course with no fear," and I honestly got emotional hearing that because that's exactly my goal: to give women mental and emotional armor to navigate the clean living space without panic.In this episode, we're chatting about:• Fluoroquinolone toxicity• Fear-based wellness content • Functional medicine accessibility• Alternative breast health screening

Fluoroquinolones (FQs) are valuable given their broad-spectrum activity against Gram-positive and Gram-negative bacteria and their high penetration into various tissues. Yet FQs have also caused concern, with some market withdrawals, important and sometimes long-lasting adverse drug events, and substantial collateral effects on the microbiota. In this episode of Communicable, hosts Emily McDonald and Thomas Tängdén invite Staffan Tevell (Karlstad, Sweden) and Bernadette Young (Oxford, UK) to weigh in on the pro-con debate of FQ use, especially for periprosthetic joint infections (PJIs), which can entail longer treatment durations. They review the standard of care for PJIs, including FQs in combination with rifampicin vs other antibiotic combinations, the impact of the OVIVA trial advocating for early oral switch strategies, the long list of rare but important side effects, and how best to preserve FQs for clinical indications that most need them.      This episode is a follow-up from Tevell and Young's recently published systematic review of the role of FQs in PJIs [1]. It was edited by Kathryn Hostettler and peer reviewed by Ljiljana Lukić of University Hospital for Infectious Diseases in Zagreb, Croatia. The executive producer of Communicable is Angela Huttner. ReferencesTevell S, et al. To heal or harm: A systematic review of the role of fluoroquinolones in periprosthetic joint infections. CMI Communications 2025. DOI: 10.1016/j.cmicom.2025.105103Further readingMandell LA, et al. Antimicrobial Safety and Tolerability: Differences and Dilemmas. Clin Infect Dis 2001. JSTOR http://www.jstor.org/stable/4461522.Pham TDM, et al. Quinolone antibiotics. Medchemcomm 2019. DOI: 10.1039/c9md00120d. Rodrigues CF and Silva F. The Rise, Fall, and Rethink of (Fluoro)quinolones: A Quick Rundown. Pathogens 2025. DOI: 10.3390/pathogens14060525Slimings C and Riley TV. Antibiotics and hospital-acquired Clostridium difficile infection: update of systematic review and meta-analysis. J Antimicrob Chemother 2014. DOI: 10.1093/jac/dkt477Davis JS, et al. Predictors of treatment success after periprosthetic joint infection: 24-month follow up from a multicenter prospective observational cohort study of 653 patients. Open Forum Infect Dis 2022. DOI: 10.1093/ofid/ofac048.Grossi O, et al. Gram- negative prosthetic joint infections managed according to a multidisciplinary standardized approach: risk factors for failure and outcome with and without fluoroquinolones. J Antimicrob Chemother 2016. DOI: 10.1093/jac/dkw202 Cortes-Penfield NW, et al. Adjunctive rifampin following debridement and implant retention for staphylococcal prosthetic joint infection: is it effective if not combined with a fluoroquinolone? Open Forum Infect Dis 2022. DOI:  10.1093/ofid/ofac582Pushkin R, et al. A Randomized Study Evaluating Oral Fusidic Acid (CEM-102) in Combination With Oral Rifampin Compared With Standard-of-Care Antibiotics for Treatment of Prosthetic Joint Infections: A Newly Identified Drug-Drug Interaction. Clin Infect Dis 2016. DOI: 10.1093/cid/ciw665Bock M, et al. Rifampicin reduces plasma concentration of linezolid in patients with infective endocarditis. J Antimicrob Chemother 2023. DOI: 10.1093/jac/dkad316   Zeller V, et al. Influence of the clindamycin administration route on the magnitude of clindamycin-rifampicin interaction: a prospective pharmacokinetic study. Clin Microbiol Infect. 2021. DOI: https://doi.org/10.1016/j.cmi.2021.04.017 Bernard L, et al. Antibiotic Therapy for 6 or 12 Weeks for Prosthetic Joint Infection. N Engl J Med 2021. DOI: 10.1056/NEJMoa2020198Vollmer NJ, et al. Safety and Tolerability of Fluoroquinolones in Patients with Staphylococcal Periprosthetic Joint Infections, Clin Infect Dis 2021. DOI 10.1093/cid/ciab145Gopalakrishnan C, et al. Association of fluoroquinolones with the risk of aortic aneurysm or aortic dissection. JAMA Intern Med 2020. DOI 10.1001/jamainternmed.2020.4199Li HK, et al. Oral versus Intravenous Antibiotics for Bone and Joint Infection (OVIVA). N Engl J Med. 2019. DOI: 10.1056/NEJMoa1710926

In This Episode You'll Learnhttps://www.drhughwegwerth.com/post/fluoroquinolone-poisoning-mold-urine-tests-show-90-toxin-drop-in-12-weeksThe Problem: How fluoroquinolone antibiotics (like Cipro) can “wake up” mold inside the body and make symptoms worse.Why Mold Lingers: Mold spores can stay in your gut or lungs for 10–30 years without you knowing.Testing Made Easy:Urine tests find mold better than blood tests because the toxins collect in pee.Three tests (Aug 2024, Nov 2024, May 2025) showed the mold levels drop.Key Results:Ochratoxin fell from 25 to 6.1.Aflatoxin went from high to zero.Mycophenolic acid vanished completely.Gentle Wins: Starting slow keeps fragile bodies safe while clearing mold.Take-Home Hope: Even if doctors said “It's all in your head,” you can heal with the right plan.Why You Should ListenClear Steps: Easy words, clear plan—perfect if medical talk confuses you.True Story: Real test dates, real numbers, real recovery.Next Move: Hear how you can book a Zoom call with Dr. Hugh for help anywhere in the world.Press play and discover that where there is help, there is hope!

I read from fluoroquinolone to flush.     The word of the episode is "flush".     Use my special link https://zen.ai/thedictionary to save 30% off your first month of any Zencastr paid plan.    Create your podcast today! #madeonzencastr     Theme music from Tom Maslowski https://zestysol.com/     Merchandising! https://www.teepublic.com/user/spejampar     "The Dictionary - Letter A" on YouTube "The Dictionary - Letter B" on YouTube "The Dictionary - Letter C" on YouTube "The Dictionary - Letter D" on YouTube "The Dictionary - Letter E" on YouTube "The Dictionary - Letter F" on YouTube     Featured in a Top 10 Dictionary Podcasts list! https://blog.feedspot.com/dictionary_podcasts/     Backwards Talking on YouTube: https://www.youtube.com/playlist?list=PLmIujMwEDbgZUexyR90jaTEEVmAYcCzuq     https://linktr.ee/spejampar dictionarypod@gmail.com https://www.facebook.com/thedictionarypod/ https://www.threads.net/@dictionarypod https://twitter.com/dictionarypod https://www.instagram.com/dictionarypod/ https://www.patreon.com/spejampar https://www.tiktok.com/@spejampar 917-727-5757

Chapters 00:00 Introduction to Derek Griffin and His Expertise 02:46 Understanding Tendinopathy and Pain Mechanisms 05:52 The Role of Subgrouping in Tendinopathy 08:59 Clinical Insights on Tendon Pain 11:53 Metabolic Factors Influencing Tendon Health 14:58 The Impact of Aging on Tendon Sensitivity 17:51 Exploring Systemic Risk Factors for Tendinopathy 21:07 The Connection Between Tendinopathy and Multi-Site Pain 23:55 Fluoroquinolones and Tendon Health 30:13 Understanding Tendinopathy and Antibiotics 31:49 Autoimmune Conditions and Tendinopathy 33:32 Screening for Inflammatory Factors 36:26 The Importance of Comprehensive Assessment 39:20 Differentiating Tendon Pain Causes 41:49 Clinical Probabilities in Tendon Pain 43:53 Referral to Specialists for Inflammatory Conditions 46:15 Managing Tendon Pain with Systemic Considerations 49:33 Impact of Medications on Tendons 50:08 Addressing Lifestyle Factors in Treatment 54:19 Barriers to Comprehensive Diagnosis 57:46 Research Gaps in Tendinopathy Understanding   Takeaways Derek Griffin has a PhD in persistent pain and focuses on tendinopathy. Tendinopathy can arise from various factors, including metabolic and autoimmune conditions. Pain mechanisms are complex and should be viewed in a biopsychosocial context. Subgrouping in tendinopathy can provide insights but should not overshadow individual treatment. Aging can increase sensitivity to tendon injuries due to metabolic changes. Metabolic syndrome is linked to poorer tendon health and healing. Fluoroquinolones are associated with increased risk of tendon rupture. Lateral hip tendinopathy often coexists with other musculoskeletal pain conditions. Understanding the patient's story is crucial for effective treatment. Tendon health is influenced by overall systemic health and lifestyle factors. Autoimmune conditions can significantly influence tendinopathy. Screening for inflammatory factors is crucial in assessment. Understanding the patient's story is key to diagnosis. Lifestyle factors should be addressed in treatment plans. There is a need for more research on non-athletic populations. The average delay in diagnosis for autoimmune conditions is significant. Medications can have varying effects on tendon health. Comprehensive assessment can improve treatment outcomes. Clinicians should routinely ask about lifestyle factors. Common sense and flexibility in treatment approaches are essential.   Derek on Twitter: https://x.com/DerekGriffin86 Derek on Instagram: https://www.instagram.com/derek_griffin_phd/ Notes: https://jackedathlete.com/podcast-134-tendons-with-derek-griffin/

Drs. Henry “Chip” Chambers and Warren Rose join Dr. Megan Klatt to tackle rifampin dosing for gram-positive infections. In this episode, they break down rifampin synergy studies and discuss what is the optimal dosing of rifampin for challenging gram-positive bacterial cases, in particular Staphylococcus aureus infections with or without retained hardware/devices.   Listen to Breakpoints on iTunes, Overcast, Spotify, Listen Notes, Player FM, Pocket Casts, TuneIn, Blubrry, RadioPublic, or by using our RSS feed: https://sidp.pinecast.co/ References: Deconstructing the Dogma: Systematic Literature Review and Meta-analysis of Adjunctive Gentamicin and Rifampin in Staphylococcal Prosthetic Valve Endocarditis. Open Forum Infect Dis. 2022 Oct 31;9(11):ofac583. doi: 10.1093/ofid/ofac583. PMID: 36408468. Effectiveness of adjunctive rifampicin for treatment of Staphylococcus aureus bacteraemia: a systematic review and meta-analysis of randomized controlled trials. J Antimicrob Chemother. 2023 Oct 3;78(10):2419-2427. doi: 10.1093/jac/dkad214. PMID: 37583062. Adjunctive Rifampin Following Debridement and Implant Retention for Staphylococcal Prosthetic Joint Infection: Is it Effective if not Combined With a Fluoroquinolone? Open Forum Infect Dis. 2022 Oct 31;9(12):ofac582. doi: 10.1093/ofid/ofac582. PMID: 36504699.

 HO HO HO, MERRY FISMAS!!!On the Third & Final Pod of FISmas these ID:IOTS have for you… 6 golden topics! Listen to hear about:1. Personalised approach to invasive fungal infection2. Agricultural anti-fungals and One Health3. Candida auris4. NTM standards of care5. Narrative reporting 6. Fluoroquinolones and the MHRA warnings Jame and Callum attended the Federation of Infection Societies 2024 annual meeting in  Liverpool; here they share their reflections on the sessions  they attended on:  a wide mix of topicsWe hope these episodes have been ADVENTatious to your learning.Notes for this episode here Send us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

What Are Mitochondria and How Fluoroquinolones Affect ThemCheck out my 65 blogs on this topicIn today's episode, Dr. Hugh will talk about mitochondria and how they play an important role in your health. This episode is especially helpful if you've been affected by antibiotics like fluoroquinolones, which can damage mitochondria.Here's what you'll learn:What are mitochondria?Mitochondria are the energy makers of your cells. They help produce power so your cells can work properly.Each cell in your body can have between 15 and 2000 mitochondria, depending on the cell type.How do fluoroquinolone antibiotics work?Medications like Cipro and Levofloxacin target the DNA of bacteria, stopping it from copying itself. This is how the bacteria are killed.However, these antibiotics can also damage your mitochondria because your mitochondria have DNA that is similar to bacterial DNA.Why are mitochondria at risk?Unlike the nucleus of your cell, which is well-protected, mitochondria have ring-shaped DNA that is exposed.This makes it easy for antibiotics to damage mitochondria, leading to long-term health problems.What happens when mitochondria are damaged?Damaged mitochondria can cause nerve pain (neuropathy) and make you feel tired.Mitochondria also help cells decide when to live or die, so when they're harmed, it can cause your cells to stop working properly.Dr. Hugh explains how fluoroquinolone antibiotics can affect your body by targeting the mitochondria. If you're struggling with side effects from these drugs, this episode will help you understand why and how to begin your path to recovery.

Free book is here at https://www.memorizingpharm.com/books Summary 3.10 Fluoroquinolones Chapter 3.10 discusses fluoroquinolones, a synthetic class of broad-spectrum antibacterial medications that inhibit bacterial DNA replication. Used to treat pneumonia, skin, and urinary tract infections, they are effective against gram-positive and gram-negative bacteria. Caution is needed due to the risk of serious side effects such as tendon rupture, neuropathy, and photosensitivity. Patients should avoid antacids and direct sunlight while taking this medication. Multiple Choice Questions Fluoroquinolones work by: a) Inhibiting protein synthesis b) Disrupting cell wall synthesis c) Blocking DNA replication d) Inhibiting RNA synthesis Which of the following is a serious side effect of fluoroquinolones? a) Weight gain b) Tendon rupture c) Increased appetite d) Hair loss Fluoroquinolones should be taken: a) With milk b) With antacids c) Two hours before or after meals d) With calcium supplements Fluoroquinolones are contraindicated in children except for: a) Ear infections b) Common cold c) Complicated UTIs d) Allergies Patients on fluoroquinolones should avoid: a) Sun exposure b) Drinking water c) Vegetables d) Carbohydrates Answer Key c) Blocking DNA replication b) Tendon rupture c) Two hours before or after meals c) Complicated UTIs a) Sun exposure  

Send us a Text Message.In this eye-opening episode, we dive into the personal journey of someone who experienced fluoroquinolone toxicity, a rare but debilitating reaction to a commonly prescribed class of antibiotics. Rachel is a wife and mom of 4, who loved being active and hiking until one day she couldn't, due to a rare reaction to a commonly prescribed medication. On this episode of Cherry Picked, Rachel shares her story of how what began as routine treatment quickly spiraled into a life-altering battle with severe side effects, including nerve damage, muscle pain, tendon damage, and mental health challenges. We explore the challenges of getting a diagnosis, navigating the healthcare system, and the road to recovery. This episode sheds light on the often overlooked dangers of certain medications and offers hope and advice for others facing similar struggles.What do you think about Cherry Picked so far?! I would love to hear your thoughts, if you have a moment, leave a review, send us a text with the link above, and make sure you are following along on socials (@cherrypickedbysav @savannah__brennan)

Their chemistry puts them in a chemotherapy drug class, and their adverse effects reflect it. Despite this, they are marketed as antibiotics and carelessly prescribed.Support the Show.

In this bonus podcast Karl Monahan talks about mental health awareness week. He opens up on his own challenges with mental health. He discusses the importance of talking and reaching out for help. Karl talks about the role of mental health in CPPS/CP conditions and reveals some shocking revelations about Fluoroquinolone antibiotics. Here is the UK Government webpage - https://www.gov.uk/drug-safety-update/fluoroquinolone-antibiotics-suicidal-thoughts-and-behaviour This is the charity CALM - https://www.thecalmzone.net/guides/suicidal-thoughts And the charity Movember - https://uk.movember.com/?home This exciting new podcast is dedicated solely to male pelvic pain conditions - Chronic Pelvic Pain Syndrome and Chronic Prostatitis Pelvic Pain Matters website - https://www.pelvicpainmatters.com/ The Pelvic Pain Clinic website - https://www.thepelvicpainclinic.co.uk/ Email Pelvic Pain Matters - pelvicpainmatters@gmail.com Email clinic - info@thepelvicpainclinic.co.uk #prostatitis #chronicpelvicpainsyndrome #chronicprostatitis #prostate #menshealth #malepelvicpain #recovery #support #urology #urologist #menshealthphysiotherapy #pelvichealth

Podcast Episode Description: Doctor Hugh's Guide to Beating Sinus Infectionswww.drhughwegwerth.comHey kids and families, welcome to our health podcast! In today's episode, Doctor Hugh, who has helped people with sinus problems for over 25 years, shares a special guide just for anyone who has had a sinus infection. Here's what we'll learn about:Who should listen?Anyone who has ever had a sinus infection.People who feel tired, have headaches, or just feel sick all the time.Why it's important:Sinus infections can make you feel really bad for a long time without you knowing it.They can cause things like brain fog, which makes it hard to think, and even affect your sleep!What will you learn?Where your sinus cavities are located in your head.A special way to check if you might still have a sinus infection by pressing on certain spots on your face.How to clear up your sinuses using some cool tools like a Navage device, which uses salt water to clean your sinuses.Special tools mentioned:Navage: A device that helps clean out your sinuses with salt water.Colloidal Silver: A natural remedy that helps kill bacteria and fungus.Percussion Massager: A device that helps break up any nasty stuff in your sinuses using vibrations.What's the big deal?Sinus infections can affect your brain because of something called the glymphatic system, which helps clean your brain. If it's not working right because of sinus issues, it can lead to more health problems.What can you do about it?Doctor Hugh will explain a step-by-step method using the Navage, colloidal silver, and a massager to help get rid of sinus infections for good.So tune in, learn all about your sinuses, and discover how to feel better if sinus infections are bothering you or your family members. Remember, understanding your body is the first step to feeling great!

Welcome to Episode 34 of “The 2 View,” the podcast for EM and urgent care nurse practitioners and physician assistants! Show Notes for Episode 34 of “The 2 View” – pertussis, computer interpretation of EKGs, TB, FQ side effects, and incidental findings Pertussis Best Practices for Healthcare Professionals on the Use of Polymerase Chain Reaction (PCR) for Diagnosing Pertussis. Pertussis: Use of PCR for diagnosis. Cdc.gov. Published January 12, 2023 https://www.cdc.gov/pertussis/clinical/diagnostic-testing/diagnosis-pcr-bestpractices.html Specimen Collection and Diagnostic Testing. Cdc.gov. Published October 11, 2023 https://www.cdc.gov/pertussis/clinical/diagnostic-testing/specimen-collection-diagnosis.html Treatment. Cdc.gov. Published September 16, 2022 https://www.cdc.gov/pertussis/clinical/treatment.html Computer Interpretation of EKGs Bracey A, Meyers HP, Smith SW. Emergency physicians should interpret every triage ECG, including those with a computer interpretation of “normal.” Am J Emerg Med. PubMed. National Library of Medicine: National Center for Biotechnology Information. Published May 2022 https://pubmed.ncbi.nlm.nih.gov/35361516/ Deutsch A, Poronsky K, Westafer L, Visintainer P, Mader T. Validity of Computer-interpreted “Normal” and “Otherwise Normal” ECG in Emergency Department Triage Patients. West J Emerg Med. PubMed. National Library of Medicine: National Center for Biotechnology Information. Published January 2024 https://pubmed.ncbi.nlm.nih.gov/38205978/ Tuberculosis CDCTB. TB Testing & Diagnosis. cdc.gov Published July 26, 2022 https://www.cdc.gov/tb/topic/testing/default.htm Global Tuberculosis Institute. Treating Latent TB Infection (LTBI). YouTube. Published November 29, 2022 https://www.youtube.com/watch?v=Udq-65YuLlo Niknejad M, Gaillard F. Tuberculosis (pulmonary manifestations). In: Radiopaedia.org. Radiopaedia.org; 2010. Revised January 5, 2024 https://radiopaedia.org/articles/tuberculosis-pulmonary-manifestations-1?lang=us Fluoroquinolone Antibiotic Side Effects Farkas J. PulmCrit - Six reasons to avoid fluoroquinolones in the critically ill. PulmCrit (EMCrit). Published August 1, 2016 https://emcrit.org/pulmcrit/fluoroquinolone-critical-illness/ FDA Drug Safety Podcast: FDA updates warnings for oral and injectable fluoroquinolone antibiotics due to disabling side effects. U.S. fda.gov Published January 19, 2022 https://www.fda.gov/drugs/fda-drug-safety-podcasts/fda-drug-safety-podcast-fda-updates-warnings-oral-and-injectable-fluoroquinolone-antibiotics-due Highlights of Prescribing Information: CIPRO. fda.gov https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/019537s086lbl.pdf Stanley I. Mother is left unable to walk after taking just three ANTIBIOTIC pills to treat a UTI: Disabled vet husband she previously cared for is also in a wheelchair. DailyMail.com. Published February 22, 2024 https://www.dailymail.co.uk/health/article-13111327/young-mother-unable-walk-antibiotic-pills-uti.html Tilley C. “Killer” antibiotic that's STILL being prescribed to 15m Americans a year: Widow of singer Bobby. DailyMail.com. Published March 2, 2024 https://www.dailymail.co.uk/health/article-13115607/Bobby-Caldwell-wife-fluoroquinolone-antibiotics.html Incidental Findings Incidental Findings. acr.org. American College of Radiology https://www.acr.org/Clinical-Resources/Incidental-Findings Schleicher S. DermDx: Suspicious Mole on Sole of Foot. Clinical Advisor. Published February 16, 2024 https://www.clinicaladvisor.com/slideshow/derm-dx/dermdx-suspicious-mole-foot/?elqtrack=True&hmemail=1f%2FJfEV7hN5vJr6vg%2FQRqK0NA6IXtyO3&hmsubid&nid=1639413404&sha256email=092493d8223fdfa40d9e995176d13e5fc5b5211674db9deb440c025fd462c80c Viennet M, Tapia S, Cottenet J, Bernard A, Ortega-Deballon P, Quantin C. Increased risk of colon cancer after acute appendicitis: a nationwide, population-based study. EClinicalMedicine. Published August 30, 2023 https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00373-5/fulltext Recurring Sources Center for Medical Education. Ccme.org. http://ccme.org The Proceduralist. Theproceduralist.org. http://www.theproceduralist.org The Procedural Pause. Emergency Medicine News. Lww.com. https://journals.lww.com/em-news/blog/theproceduralpause/pages/default.aspx The Skeptics Guide to Emergency Medicine. Thesgem.com. http://www.thesgem.com Trivia Question: Send answers to 2viewcast@gmail.com Be sure to keep tuning in for more great prizes and fun trivia questions! Once you hear the question, please email us your guesses at 2viewcast@gmail.com and tell us who you want to give a shout-out to. Be sure to listen in and see what we have to share!

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Tous les jours, à 14h20, RMC s'engage pour vous. Amélie Rosique et la rédaction de RMC trouvent des solutions aux questions et problèmes du quotidien des auditeurs. Envoyez vos messages par e-mail: rmcavecvous@rmc.fr.

In this episode, we review the high-yield topic of⁠ ⁠Fluoroquinolones⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Microbiology section. Follow ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://podcasters.spotify.com/pod/show/medbulletsstep1/message

Nurses Out Loud with Nurse Michele, RN – Striking a balance between promoting diversity and maintaining high standards may seem crucial in today's culture, but clearly, patient care and quality skilled staff should always outweigh DEI standards. It's essential for medical institutions to navigate this transition thoughtfully, ensuring that DEI initiatives complement, rather than overshadow, the fundamental requirement of medical expertise in delivering optimal healthcare...

Nurses Out Loud with Nurse Michele, RN – Striking a balance between promoting diversity and maintaining high standards may seem crucial in today's culture, but clearly, patient care and quality skilled staff should always outweigh DEI standards. It's essential for medical institutions to navigate this transition thoughtfully, ensuring that DEI initiatives complement, rather than overshadow, the fundamental requirement of medical expertise in delivering optimal healthcare...

In this podcast recorded in early January, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the February 2024 issue of DTB. They discuss the editorial that highlights problems associated with shortages of ADHD medicines.  They talk about two safety alerts issued by the Medicines and Healthcare products Regulatory Agency that focus on the adverse effects of fluoroquinolone antibiotics on physical and mental health.  The main article considers various NHS initiatives that have attempted to limit primary care prescribing of drugs that are deemed to have limited clinical value. They begin the podcast with sad news of the death of Dr Sidney Wolfe (1937-2024), a colleague and friend who co-founded the US Health Research Group and Public Citizen (a nonprofit consumer advocacy organisation) and who was "a towering public health leader and an unparalleled consumer champion".    Links Remembering Sid Wolfe: https://www.citizen.org/remembering-sidney-wolfe/ Mandatory disclosure of all pharmaceutical and medical device companies' payments to healthcare providers: learning from the US: https://dtb.bmj.com/content/60/4/52 Worst Pills, Best Pills: https://www.citizen.org/topic/safe-affordable-drugs-devices/worst-pills-best-pills/ Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). If you want to contact us please email dtb@bmj.com. Thank you for listening.

On episode #46 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/4 – 1/17/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Comparing the performance of three models incorporating weather data to forecast dengue epidemics (JID) Elucidating the impacts of climate on dengue transmission through mathematical models (JID) Infants receiving a single dose of nirsevimab to prevent RSV do not have evidence of enhanced disease in their second RSV season (JPIDS) Patient perspectives on solid organ transplantation from donors with hepatitis C viremia to recipients without hepatitis C viremia (OFID) Oral Beta-Lactams, Fluoroquinolones, or Trimethoprim-Sulfamethoxazole for definitive treatment of uncomplicated Escherichia coli or Klebsiella species bacteremia from a urinary source (OFID) Discontinuation of contact precautions for methicillin-resistant Staphylococcus aureus in a pediatric healthcare system (JPIDS) Oral linezolid compared with benzathine PCN G for treatment of early syphilis in adults (The Lancet) Model-informed precision dosing improves outcomes in patients receiving vancomycin for gram-positive infections (OFID) The Xpert MTB/RIF cycle threshold value predicts M.tuberculosis transmission to close contacts (CID) Efficacy and safety of a structured de-escalation from antipseudomonal β-lactams in bloodstream infections due to Enterobacterales (The Lancet) Oral antibiotics for treatment of Gram negative bacteremia in solid organ transplant recipients (CID) Dematiaceous fungal keratitis with tentacles mimicking Pythium Keratitis (Jama) Verification, analytical sensitivity, cost-effectiveness, and comparison of four Candida auris screening methods (OFID) Tafenoquine-Atovaquone combination achieves radical cure and confers sterile immunity in experimental models of human babesiosis (JID) Relapsing babesiosis with molecular evidence of resistance to certain antimicrobials commonly used to treat Babesia microti infections (OFID) Understanding parental leave policies in ID fellowship (OFID) What's hot this year in ID clinical science (CID) Music is by Ronald Jenkees

PodChatLive 110: Distracted gait, no more fluoroquinolones and a brand new review on running injury Contact: getinvolved@podchatlive.com Links for this episode: Is this the most expensive regular running shoe? Does listening to audiobooks affect gait behavior? Distracted Walking Fluoroquinolone antibiotics Do Exercise-Based Prevention Programs Reduce Injury in Endurance Runners?

We find out what the cattle market for 2024 could hold.  We have updates on your latest antibiotic usage plan, a great set of efficient cows for sale, plus how to make buying bulls easier than you ever imagined.  Join Jeff 'Tigger' Erhardt, the Boss Lady Rebecca Wanner aka 'BEC', and our crew as we bring you the latest in markets, news, and Western entertainment on this all-new episode of the Ranch It Up Radio Show.  Be sure to subscribe on your favorite podcasting app or on the Ranch It Up Radio Show YouTube Channel. EPISODE 166 DETAILS 2023 turned out to be an awfully good year to be in the cattle business.  Prices were record setting for many producers and hopefully yall were able to take advantage of them.  But the big question is what does 2024 hold?  Well, no one knows for sure or has a crystal ball but forecasts look promising.  We visit with Kirk Donsbach from Stone X Financial about cattle trends for the next year! When it comes to choosing the right antibiotic to treat cattle, it should be anything but a guessing game. While there are many factors that weigh into creating a treatment regimen, understanding the different classes of antibiotics and how they work is important to ensure your cattle are getting the best treatment response.  We have some great information curiosity of Elanco Animal Health!  Click HERE for additional information! We just made purchasing your next herd sire so much easier!  All the information you need to know including vidoes, sale books, pictures, information about the sale date and location, websites, contact info and much more can be found on the all new Ranch Channel!  Check it out!   ANTIBIOTICS 101 - TIPS FOR CHOOSING THE RIGHT TREATMENT FOR YOUR BEEF CATTLE When it comes to choosing the right antibiotic to treat cattle, it should be anything but a guessing game. While there are many factors that weigh into creating a treatment regimen, understanding the different classes of antibiotics and how they work is important to ensure your cattle are getting the best treatment response.   A variety of infectious diseases can compromise cattle health, affecting growth, performance and operational profitability. Bovine Respiratory Disease (BRD) is one of the most common and costly. Prevention is the first line of defense against BRD. Having management protocols in place to reduce risk factors, along with a vaccine program, can help protect your herd. But when animals do get sick, it's vital to identify and treat cattle as soon as possible with the right treatment to ensure the longevity of treatment options and reduce the risk of resistance.   Not all antibiotics are created equal Every antibiotic has a different mix of characteristics. Knowing the antibiotic class and its characteristics when treating cattle gives a better understanding of how it works. Two of the most common antibiotic classes used to treat respiratory disease in cattle are macrolides and fluoroquinolones. Macrolides are time-dependent bacteriostatic antibiotics. This means they must maintain a minimal concentration that is greater than the minimum inhibitory concentration (MIC) over a period of time to overcome infectious bacteria. The MIC is the minimum amount of drug needed to suppress the replication of bacteria. The longer the antibiotic is present in the animal at or above the MIC level, the more it inhibits bacteria reproduction so allowing time for macrolides to work is critical. In certain “bug-drug” combinations such as tulathromycin and some isolates of Mannheimia haemolytica, macrolides can be bactericidal making initial concentrations and appropriate dosing more critical. Fluoroquinolones are concentration-dependent bactericidal antibiotics. This means they only need to reach concentrations above the MIC for very short periods to be effective. In some models, the higher the initial concentration of the fluoroquinolone above the MIC, the more effective the therapy. How to choose the correct antibiotic Understanding how an antibiotic works is one step to minimizing the risk of resistance. There are a few things producers should ask themselves when choosing an antibiotic to make the right choice for their operation: Do I know the health history of the cattle being treated? If there was a metaphylaxis treatment with one class of antibiotic, using a different class if subsequent treatment is required may be warranted. Do I know the weight of the animal being treated? Remember when administering antibiotics, the dose is based on weight of the animal. Getting an accurate weight on each animal being treated is important to the success rate of antibiotic therapy. What is the causative pathogen? Necropsies are an excellent tool to understand what bacteria your cattle are challenged with. Cultures can help determine what bacteria is affecting your herd and the best treatment for that strain. Have I read the product label? Once you understand the bacteria strain you're dealing with, it's important to choose a product that's labeled to control or treat that associated bacteria. It's also important to ensure you are following directions for proper dosage, route of administration and withdrawal periods to get the most effective treatment. Do I have bigger issues to address? When seeing an uptick in BRD cases, we can often put the blame on animal health products. It's important to remember medicine cannot overcome poor management. Good animal husbandry and management practices, reducing stress and a solid nutrition program are critical to positive animal health. Work with your veterinarian to determine where current practices may be contributing to illness. Producers should consult their veterinarian to help them choose appropriate classes of antibiotics and consider antibiotic characteristics such as the spectrum of activity, mode of action, duration of action, efficacy and withdrawal period to help them treat their herd responsibly. With consistent, thorough application of best practices, the responsible use of antibiotics will help ensure the health of animals and improve food safety for the next generation and beyond.   To learn more about tools to help control, treat and prevent BRD on your operation, talk with your Elanco representative or visit ElancoBRD.com.   FEATURING Kirk Donsbach: Stone X Financial https://www.stonex.com/   @StoneXGroupInc      Mark Van Zee  Livestock Market, Equine Market, Auction Time https://www.auctiontime.com/ https://www.livestockmarket.com/ https://www.equinemarket.com/ @LivestockMkt @EquineMkt @AuctionTime   Shaye Koester Casual Cattle Conversation https://www.casualcattleconversations.com/ @cattleconvos Questions & Concerns From The Field? Call or Text your questions, or comments to 707-RANCH20 or 707-726-2420 Or email RanchItUpShow@gmail.com FOLLOW Facebook/Instagram: @RanchItUpShow SUBSCRIBE to the Ranch It Up YouTube Channel: @ranchitup Website: RanchItUpShow.com https://ranchitupshow.com/ The Ranch It Up Podcast available on ALL podcasting apps. Rural America is center-stage on this outfit. AND how is that? Because of Tigger & BEC... Live This Western Lifestyle. Tigger & BEC represent the Working Ranch world by providing the cowboys, cowgirls, beef cattle producers & successful farmers the knowledge and education needed to bring high-quality beef & meat to your table for dinner. Learn more about Jeff 'Tigger' Erhardt & Rebecca Wanner aka BEC here: TiggerandBEC.com https://tiggerandbec.com/ #RanchItUp #StayRanchy #TiggerApproved #tiggerandbec #rodeo #ranching #farming References https://www.stonex.com/ https://www.livestockmarket.com/ https://www.equinemarket.com/ https://www.auctiontime.com/ https://gelbvieh.org/ https://www.imogeneingredients.com/ https://alliedgeneticresources.com/ https://westwayfeed.com/ https://medoraboot.com/ https://www.bek.news/dakotacowboy http://www.gostockmens.com/ https://www.lucky7angus.com/ https://www.bredforbalance.com/ https://www.wasemredangus.com/ https://farmanimal.elanco.com/us/brd-management-with-elanco?utm_source=Elanco&utm_medium=Article&utm_campaign=23-ELA-0388&utm_term=Beef-Hub&utm_content=Antibiotics-101 https://ranchchannel.com/ https://farmanimal.elanco.com/us/brd-management-with-elanco

The AMR sub-series is back! Dr. Minkey Wungwattana joins Luis and Andrea in the podcast to talk about fluoroquinolones. What is the mechanism of action of this class of antimicrobials? What organisms do they have activity against? What about breakpoints for Salmonella? Tune in to find out.Link to breakpoints episode that Andrea mentioned:https://rss.com/podcasts/letstalkmicro/475955/

Trevor's Triumph Over Prostatitis and Fluoroquinolone Toxicity with Red Light Therapy and Methylene Bluewww.drhughwegwerth.comWelcome Listeners!Today, we're diving into Trevor's inspiring 30-year journey, battling both prostatitis and fluoroquinolone toxicity. Trevor, from Durban, South Africa, shares his story of resilience and path to healing.Episode Highlights:Early Challenges with Prostatitis: Discover how Trevor's health issues began with prostatitis in his 30s and the complications that arose from repeated fluoroquinolone treatments.Ongoing Symptoms and Surgeries: Hear about Trevor's experience with surgeries for his enlarged prostate and the relentless struggle with symptoms of being 'floxed.'Shift to Functional Medicine: Learn about the pivotal role functional medicine played in Trevor's recovery, leading to an impressive 90% improvement.Dietary Changes for Gut Health: Trevor talks about the major diet adjustments and supplements that helped enhance his gut health and overall wellness.Innovative Treatment Approaches:Red Light Therapy: Explore how red light therapy became a crucial part of Trevor's recovery process.Methylene Blue Therapy: Gain insights into Trevor's use of methylene blue and its impact on his recovery from fluoroquinolone toxicity.Medication Management: Trevor shares how the improvement in his health allowed him to reduce medication use and tackle other health issues.Trevor's Advice: Concluding the episode, Trevor advocates for natural treatments over traditional methods and emphasizes the importance of persistence and a positive mindset in overcoming chronic health conditions.Join us to get inspired by Trevor's incredible journey of overcoming prostatitis and fluoroquinolone toxicity through red light therapy, methylene blue, and a holistic health approach!

HR1 Dr. Scott: Stem Cells Revolution. Hurt by Cipro, Levaquin, Fluoroquinolone Antibiotics? 11-29-23 by John Rush

In this episode, Emily Heil, PharmD, MS, BCIDP, AAHIVP; Laila Woc-Colburn, MD; and Trevor Van Schooneveld, MD, FSHEA, FACP, discuss their approach to managing infections involving carbapenem-resistant Acinetobacter baumannii (CRAB), including: Mechanisms for β-lactam resistanceAdditional resistance mechanisms and virulence factors2023 IDSA guidance recommendations for moderate to severe CRAB infectionsThe latest clinical data by antimicrobial therapy/regimen:SulbactamMeropenem and colistinCarbapenem, sulbactam, and polymyxin BTetracyclinesCefiderocolSulbactam/durlobactam and carbapenems Program Director:Trevor Van Schooneveld, MD, FSHEA, FACP Professor, Division of Infectious DiseasesProgram Director, Infectious Diseases FellowshipMedical Director, Antimicrobial Stewardship ProgramUniversity of Nebraska Medical CenterOmaha, NebraskaFaculty:Emily Heil, PharmD, MS, BCIDP, AAHIVPAssociate ProfessorDepartment of PharmacyUniversity of Maryland School of PharmacyID Clinical Pharmacy SpecialistUniversity of Maryland Medical CenterBaltimore, MarylandLaila Woc-Colburn, MDAssociate ProfessorDivision of Infectious DiseasesEmory University School of Medicine Atlanta, GeorgiaContent based on a CME program supported by an educational grant from Merck & Co., Inc., Rahway, NJ, USA.Follow along with a downloadable slideset at: https://bit.ly/476v2wILink to full program: https://bit.ly/40Mmicz

In this episode, Lillian Abbo, MD, MBA, FIDSA, discusses appropriate antimicrobial selection for managing uncomplicated UTIs, including:Balancing discrepancies in available guidelines Individualizing antimicrobial selection based on patient characteristics and local resistance patterns Incorporating tools, like antibiograms, into daily practice Being a good steward of currently available antimicrobial agents Planning ahead for emerging therapies for uncomplicated UTIsPresenter:Lillian Abbo, MD, MBA, FIDSAAssociate Chief Medical Officer Infectious DiseasesJackson Health SystemProfessor of Clinical Infectious DiseasesUniversity of Miami Miller School of MedicineMiami Transplant InstituteMiami, FloridaFind other program activities here: “Uncomplicated” Doesn't Mean Easy: Recognizing the Burden and Preventing Treatment Failure of Uncomplicated UTIsSlides on “Uncomplicated” Doesn't Mean Easy: Recognizing the Burden and Preventing Treatment Failure of Uncomplicated UTIsPodcast 1: Burden on Uncomplicated Urinary Tract InfectionsPodcast 3: When Things Get Complicated: Managing uUTIs in Acute CareClinicalThought: Not Always an Easy Task: Antimicrobial Stewardship for Uncomplicated UTIs

In this episode, Lilly C. Lee, MD, SM, FACEP, FAAEM, discusses the best practices in management of uUTI in the emergency department, including:Patient triageDiagnostic stewardshipInterdisciplinary careStrategies to overcome treatment barriersPresenter:Lilly C. Lee, MD, SM, FACEP, FAAEMChief of Emergency MedicineJackson Memorial HospitalFlorida Poison Information CenterRoxcy Bolton Rape Treatment CenterAffiliated Assistant Professor of SurgeryDeWitt Daughtry Family Department of SurgeryLeonard M. Miller School of MedicineUniversity of MiamiMiami, FloridaFind other program activities here: “Uncomplicated” Doesn't Mean Easy: Recognizing the Burden and Preventing Treatment Failure of Uncomplicated UTIsSlides on “Uncomplicated” Doesn't Mean Easy: Recognizing the Burden and Preventing Treatment Failure of Uncomplicated UTIsPodcast 1: Burden on Uncomplicated Urinary Tract InfectionsPodcast 2: Updates in Antimicrobial Selection for uUTIsClinicalThought: When Care Gets Complicated: Uncomplicated UTI Management in Acute Care Settings 

Intro:Ever imagined taking medicine for a minor breathing issue and then finding yourself in a wheelchair? Taylor and many others, called "floxies", lived it. Join us as we uncover the surprising journey from fluoroquinolone toxicity to renewed health.www.DrhughWegwerth.comTopics Covered:The Fluoroquinolone Shock:What Happened? Taylor's sudden shift from simple treatment to battling with the harsh side effects of fluoroquinolone.Being 'Floxed' Defined: The whirlwind of pain, unexpected symptoms, and the widespread call for hope among the "floxies".Finding a Way Out:Doctor Visits: The hunt for answers, solutions, and how to really recover from being floxed.Dietary Solutions: The surprising discovery that changing what you eat can be a big help in battling fluoroquinolone side effects.Wellness Tools for Recovery:Supplement Power: Combining magnesium glycinate, omega-3 fish oil, and caprylic acid as key helpers.The Right Diet: How changing what's on the plate can reduce pain and be a major tool in the healing process.Believing in Recovery:It Takes Time: Patience, trust, and the right treatments can lead the way.Get the Right Help: The importance of having a knowledgeable healthcare provider by your side.The Light at the End:Taylor and fellow floxies show that with determination and the right tools, it's possible to overcome the challenges of being "floxed".

Today on the show: Dive deep into Adam's compelling journey as he confronts the challenges of fluoroquinolone toxicity and finds his floxie hope amidst adversity.In this episode, we'll uncover:Adam's Personal ExperienceHow he grappled with the sudden realization of being floxedHis unexpected battle with fluoroquinolones side effectsUnmasking the Problem:How initial subtle symptoms quickly escalatedAdam's pursuit of a fluoroquinolone toxicity test and potential fluoroquinolone toxicity treatment optionsMagnesium - The Game ChangerThe importance of magnesium in Adam's how to heal from floxing journeyDaily regimen: The significance of a hefty 1000mg of magnesium as a supplement for fluoroquinolone toxicityNature's Healing Wonders:Adam shares his arsenal of natural floxed treatment strategiesThe brilliance of mother nature in his path to how to recover from being floxedThe Power of BalanceAdam's blend of martial arts and mindfulness in his floxie hope journeyEmbracing non-combative principles for how to heal from floxingThe All-Around ApproachGoing beyond just easing fluoroquinolones side effectsDelving deep to treat the root causes of fluoroquinolones toxicityStaying One Step AheadAdam's preventive tactics against fluoroquinolone toxicityHis proactive methods to evade the threats of fluoroquinolones toxicitySleeping Right:Combating blue light and adopting self-massageRecognizing sleep's crucial role in the fluoroquinolone toxicity treatment processMind Over MatterAdam's mental journey in overcoming fluoroquinolone toxicityHis testament to perseverance and finding floxie hopeThe Emotional RollercoasterMoving from misdiagnosis to reliefA vivid retelling of coping with fluoroquinolones side effectsInspiration for ManyAdam's lessons and the beacon of light they provideOffering hope to those sailing the turbulent waters of fluoroquinolone toxicityAdam's Final Nuggets of WisdomAn inspiring tale of triumph over fluoroquinolone toxicityWords that embolden and inspire all facing this challengeJoin us as Adam turns adversity into an enlightening tale of hope, strength, and recovery. Don't miss these invaluable insights into fluoroquinolones toxicity and its treatments!

Episode Overview:Join us today as we dive deep into a riveting medical mystery! We'll uncover the challenges faced by a 45-year-old doctor after an unexpected reaction to a medicine called fluoroquinolone. With the expertise of Dr. Hugh Wegwerth from Rosemount, Minnesota, there's hope in sight.Episode Highlights:The Backstory: Discover the tale of an Afghan physician whose life changed after taking fluoroquinolone.Main symptoms: Feeling very sad, low energy, mixed-up thoughts, and big mood swings.The Gut-Brain Connection:Dr. Hugh's take: A healthy gut is super important to fix "floxed" symptoms!Fun fact: Our gut is home to lots of our immune system!Lab Results Deep Dive: What's happening inside?Findings: Different blood issues, infections, sugar problems, and missing nutrients.Healing Path: Dr. Hugh's step-by-step plan!Diet tip: Eat keto-friendly foods.Helpful supplements: Magnesium, fish oil, and cool stuff like lion's mane mushroom.Secret sauce: Adjust and go slow with treatments.Progress Check-in: Two Weeks LaterGood news: Better sleep, mood, and fewer scares.Still working on: Some small issues like seeing spots.Bright Future: Recovery isn't just a dream!Winning strategy: A full treatment plan can help people get better.Final Thoughts:Fluoroquinolone Toxicity might sound scary, but with understanding and the right help, getting better is totally possible! Make sure to check out Dr. Nasi MD's video on recovery and contact Dr. Hugh if you need more advice.Remember, always believe in hope and never give up on health!

Fluoroquinolones such as Cipro, Levaquin and Avelox are antibiotics commonly used to treat or prevent serious bacterial infections such as sinusitis, bronchitis and urinary tract infections. According to the Centers for Disease Control statistics, American doctors wrote nearly 30 million fluoroquinolone antibiotic prescriptions in 2016.  A 2016 FDA safety review stated that fluoroquinolones are associated with disabling and potentially permanent serious side effects that can occur together. These side effects can involve the tendons, muscles, joints, nerves, and central nervous system. Fluoroquinolone toxicity can cause severe mitochondrial damage in the body. This condition is commonly misdiagnosed as lymes, MS, arthritis, fibromyalgia among others.  Kiley Woodland is a singer songwriter and recording artist and was opening for KISS with her band shortly before she was given cipro, one of the most commonly prescribed antibiotics, which ended up causing such severe debilitating side effects it put her in a wheelchair.  Kiley has since started sharing her journey to educate others on the dark side of fluoroquinolone antibiotics that often no one is told about. In this episode she talks about how fluoroquinolones harm the cells, the "fluoroquinolone bomb going off", where genetics and nutrient deficiencies play in to a recovery plan, and the two most important minerals that are chelated out with fluoroquinolone toxicity. Her Instagram: https://www.instagram.com/celebratethelittlewins/ Her upcoming website: www.celebratethelittlewins.com My website: www.matt-blackburn.com Mitolife products: www.mitolife.co Music by George Henner https://georgehenner.bandcamp.com/  

‘Fluoroquinolone' antibiotics are unfortunately notorious for causing tendon damage – including Golfer's and Tennis Elbow and, more seriously, Achilles Tendon ruptures. (Cipro being the most well-known and often prescribed drug in this class)

On episode #31 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/8 – 6/20/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Relative effectiveness of the cell-based quadrivalent influenza vaccine in preventing cardiorespiratory hospitalizations (OFID) Evaluation of Oseltamivir used to prevent hospitalization in outpatients with influenza (JAMA) Pan-ebolavirus monoclonal antibody cocktail provides protection against Ebola and Sudan viruses (JID) Inappropriate antibiotic prescribing and its determinants among outpatient children in low-and middle-income countries (PLOS) IDSA 2023 Guidance on the treatment of antimicrobial resistant gram-negative infections (IDSA) Evaluating antimicrobial duration for gram-negative bacteremia in patients with neutropenia (TID) Antibiotic myths for the ID clinician (CID) Dalbavancin for the treatment of acute bacterial skin and skin structure infection in patients with obesity or Diabetes (OFID) Global differences in the management of S. aureus bacteremia (CID) Clinical risk Scores to Predict Trimethoprim-Sulfamethoxazole, Fluoroquinolone, Nitrofurantoin, and Cephalosporin non-susceptibility among outpatient episodes of complicated UTI among adults (OFID) Continuous vs intermittent meropenem administration in critically ill patients with sepsis (JAMA) Current pyuria cutoffs promote inappropriate UTI diagnosis in older women (CID) Paenibacillus infection as a novel cause of sepsis in term neonates with high risk of sequelae in Uganda (CID) Antimicrobial for 7 or 14 Days for febrile urinary tract infection in men (CID) Candida auris‒associated hospitalizations (EID) Fatal invasive mold infections after transplantation of organs recovered from drowned donors (EID) Music is by Ronald Jenkees

Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions:    Chris: Hi doctor Cabral. Absolutely love anything you are doing for the world. I just have a question regarding silica dust. I work in construction and although I do everything I can to prevent inhaling the dust, it is extremely hard to keep myself from breathing in some dust every day. I know how deadly silicosis can be and was wondering if there were ways that I could help rid the body of any built up silica dust in my lungs? I was also wondering if there was a lab/test that would indicate if I had high levels of silica in my body? Thanks for everything you do Chris   Tamara: HI DR. Cabral Can you tell me is it safe to eat off of Cornell brand plates and bowls? Thanks for all you do!   Amy: Hello Dr. Carbral! I have a Oura ring, but I feel like I'm not using it to its full capability. Where is the best place to find info on healthy parameters (HR, HRV, sleep time, etc)? Thanks!   Anonymous: Hi doc! Been gung ho on natural health for about 5 yrs. Threw in 100% with you about a year ago after binging your podcast for a year. Been through many of your protocols with little progress with my gut, still100% committed to the protocols & living a healthy lifestyle. I struggle a lot with stress anxiety & low mood. I had a 6in fibroadenoma removed from my left breast in 2014 & lately I feel like it's coming back. Large lump on the back of my left shoulder for 10 yrs. Also within the last year I've grown a mobile grape sized lump on the back of C6. Gut lymph dumping grounds perhaps? Been working so hard following everything to the T, so why is my gut not healing & what's with all these lumps especially if the body regenerates within a year? Stress? I get so frustrated & scared. Thanks!   Nicole: Hi! I've suffered from a strange vibration in my chest that comes with each heartbeat. It started a few months ago & initially only in the evenings. Now I'm having it most of the day except while lying down & resting. More recently I've also developed some random come & go twitches in my leg, eye lid, arm & vibrations that come & go in my ankle and hip. I've seen doctors, run tests of all sorts including HTMA & all look fairly good. I've been to a cardiologist who after doing testing diagnosed me with mild mitrial valve prolapse, mild regurgitation & mild mitrial valve thickening. He says he's not concerned & I shouldn't be having these symptoms from it. My thoughts are possibly my nerves have become sensitive due to recent stresses & maybe dysautonomia? What are your thoughts on this?   Aly: Hi Dr. Cabral, is it possible to heal from Fluoroquinolone toxicity, or is this something that can permanently damage mitochondria and therefore something that has to be managed for the rest of my life? I was disabled by Cipro for 6 months, and I can now walk short distances. I still have tendon and ligament damage in my neck, elbows, knees and Achilles. I'll do anything to heal--hot and cold therapy, supplements, morning sunlight, diet changes, and more. Eager to hear your thoughts on this!   Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!      - - - Show Notes and Resources: StephenCabral.com/2661 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

https://www.drhughwegwerth.com/post/floxed-how-fluoroquinolones-affect-mitochondriaJoin Dr. Hugh Wegwerth in his captivating podcast episode titled "How Antibiotics Affect Mitochondria." Delve into the intriguing world of cellular dynamics as Dr. Wegwerth unravels the profound impact of fluoroquinolone antibiotics on both bacteria and mitochondria.Discover the groundbreaking mechanisms by which antibiotics eliminate bacteria, as Dr. Wegwerth sheds light on the relentless battle against bacterial resistance. Explore the development of fluoroquinolones as a potent alternative, targeting bacterial DNA with the aid of fluoride molecules. Uncover the riveting details of how this unique class of antibiotics inhibits replication and leads to the ultimate demise of bacterial cells.But the story doesn't end there. Venture deeper into the biological realm and unlock the astonishing similarities between bacteria and mitochondria. Dr. Wegwerth reveals the evolutionary origins of mitochondria as independent bacteria that gradually formed a symbiotic relationship with humans. Marvel at the shared traits of bacteria and mitochondria, including their size, reproduction methods, and the arrangement of DNA within their cellular structures.Prepare to be amazed as the podcast episode unveils the critical role of mitochondria in energy production through ATP synthesis. Yet, here lies the twist – fluoroquinolones, in their indiscriminate assault, fail to differentiate between harmful bacteria and beneficial mitochondria. Consequently, these antibiotics launch an attack on mitochondrial DNA, disrupting replication and impairing vital energy production processes. Brace yourself for a journey through the far-reaching consequences of mitochondrial dysfunction, affecting cells, organs, and overall well-being. Symptoms and conditions like leaky gut, dry mouth, and neuroinflammation surface as a result of damaged mitochondria, reverberating throughout the body's various systems.As the episode reaches its climax, Dr. Wegwerth emphasizes the profound cellular impact of fluoroquinolone antibiotics. He enlightens listeners on the ease with which these antibiotics penetrate cell and mitochondrial membranes, sounding a warning bell for potential harm. In this era of increased awareness, he advocates for a deeper understanding of the repercussions antibiotics can have on mitochondria, urging us to safeguard our cellular powerhouses.In this thought-provoking podcast episode, "How Antibiotics Affect Mitochondria," Dr. Hugh Wegwerth invites you on an enlightening exploration of the cellular consequences of fluoroquinolone antibiotics. Brace yourself for a captivating journey into the world of DNA, bacteria, mitochondria, and the intricate web of life within our cells.

In this episode, David van Duin, MD, PhD, FIDSA, FAST, discusses new data on complicated clinical infections presented at ECCMID 2023, including:Gram-negative resistancePharmacokinetic and clinical outcomes in patients receiving meropenem/vaborbactam for KPC-producing carbapenem-resistant Enterobacterales infectionsComparative study of cefiderocol- vs colistin-containing regimens for CRAB VAP with concomitant bacteremiaReal-world use of imipenem/cilastatin/relebactam for the treatment of infections caused by multidrug-resistant organismsAntimicrobial stewardshipSafety and efficacy of antibiotic de-escalation from an antipseudomonal β-lactam in patients with Enterobacterales BSIs in SIMPLIFYThe SOAB study comparing clinical outcomes of switching to oral antibiotics after IV lead-in therapy vs continuing IV therapy in patients with Enterobacterales BSIsData from REGARD-VAP on outcomes of shortened antibiotic treatment for VAP guided by clinical criteriaInvestigational agentsOpen-label study following ATTACK of patients with colistin-resistant CRAB infections receiving sulbactam/durlobactamSummary of findings from EAGLE-2 and EAGLE-3 of gepotidacin for uncomplicated UTI treatmentPost hoc DOOR analysis of SURE-2 of sulopenem for the treatment of complicated UTIs Faculty: David van Duin, MD, PhD, FIDSA, FAST Professor of Medicine Director, Immunocompromised Host Infecious Diseases Program Division of Infectious Diseases University of North Carolina Chapel Hill, North Carolina Content based on an online CME/CE program supported by an independent educational grant from Shionogi Inc. Link to full program: https://bit.ly/3niXGJ6Link to downloadable slides: https://bit.ly/3Hx0ppn

Episode Notes Drs. Jim Lewis, Mike Satlin (@MSatlin) and Jason Pogue (@jpogue1) are back with Dr. Erin McCreary (@ErinMcCreary) for episode four of a five-episode miniseries all about breakpoints! Join our panelists for a magically delicious episode all about breakpoint updates on fluoroquinolones. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm (https://twitter.com/SIDPharm) Instagram: @SIDPharm (https://www.instagram.com/sidpharm/) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/company/sidp/ Listen to Breakpoints on iTunes, Overcast, Spotify, Listen Notes, Player FM, Pocket Casts, Stitcher, Google Play, TuneIn, Blubrry, RadioPublic, or by using our RSS feed: https://sidp.pinecast.co/ Check out our podcast host, Pinecast. Start your own podcast for free with no credit card required. If you decide to upgrade, use coupon code r-7e7a98 for 40% off for 4 months, and support Breakpoints.

TWiM reveals housefly dispersal of antimicrobial resistant bacteria, and a reproductive organ in squid linked to symbiotic bacteria.   Become a patron of TWiM Links for this episode Housefly dispersal of antimicrobial resistant E. coli (Appl Micro Int) Antibiotic use in farming (Nature) Antimicrobial use in food producing animals (PLoS Glob Pub Health) Reproductive organ linked to symbiotic bacteria (mBio) Skype a Scientist Take the TWiM Listener survey! Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv

The controversy surrounding whether to collect urine cultures and which empiric treatment to prescribe in patients with uncomplicated UTI has left many clinicians unsure of the right approach. In this the first episode of a podcast series, we'll discuss the definition of clinical cure and dive into the evidence behind grey areas in the diagnosis and management of uncomplicated UTI. Disclaimers: This presentation is sponsored by GSK. The speakers are GSK paid healthcare providers. The content is intended to support disease state education and is considered nonpromotional. The content and views expressed therein do not necessarily reflect the views, policies, or position of Pri-Med. This program is limited to Health Care Professionals (HCPs) only. GSK complies with all state and federal laws including transparent reporting and disclosure of payments and transfers of value to HCPs.   References: Gupta K, Hooton TM, Naber KG, et al.; Infectious Diseases Society of America; European Society for Microbiology and Infectious Diseases. International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases. Clin Infect Dis. 2011;52(5):e103- e120. doi: 10.1093/cid/ciq2572. Anger J, Lee U, Ackerman AL, et al. Recurrent uncomplicated urinary tract infections in women: AUA/CUA/SUFU guideline. J Urol. 2019;202(2):282-289. doi: 10.1097/JU.00000000000002963 Houlbar M, Meng L. SHC Clinical Pathway: Inpatient Management of Urinary Tract Infections – Adult Patients. Stanford Antimicrobial Safety and Sustainability Program. November 2017. https://med.stanford.edu/content/dam/sm/bugsanddrugs/documents/c linicalpathways/SHC-UTI-Inpatient-Guideline.pdf. Accessed November 30, 2022. Hooton TM, Gupta K. Acute simple cystitis in women. UpToDate. Updated March 15, 2021. Accessed November 9, 2022. https://www.uptodate.com/contents/acute-simple-cystitis-in-women Colgan R, Williams M. Diagnosis and treatment of acute uncomplicated cystitis. Am Fam Physician. 2011;84(7):771-776. Shafrin J, Marijam A, Joshi AV, et al. Impact of suboptimal or inappropriate treatment on healthcare resource use and cost among patients with uncomplicated urinary tract infection: an analysis of integrated delivery network electronic health records. Antimicrob Resist Infect Control. 2022;11(1):133. Published 2022 Nov 4. doi:10.1186/s13756-022-01170-3 Daneman N, Chateau D, Dahl M, et al. Fluoroquinolone use for uncomplicated urinary tract infections in women: a retrospective cohort study. Clin Microbiol Infect. 2020;26(5):613-618. doi:10.1016/j.cmi.2019.10.016 Bratsman A, Mathias K, Laubscher R, Grigoryan L, Rose S. Outpatient fluoroquinolone prescribing patterns before and after US FDA boxed warning. Pharmacoepidemiol Drug Saf. 2020;29(6):701-707. doi:10.1002/pds.5018 FDA Drug Safety Communication. FDA. 2019. Accessed October 10, 2022 https://www.fda.gov/drugs/drug-safety-and-availability/fda-warns[1]about-increased-risk-ruptures-or-tears-aorta-blood-vessel[1]fluoroquinolone-antibiotics Nicolle LE; AMMI Canada Guidelines Committee*. Complicated urinary tract infection in adults. Can J Infect Dis Med Microbiol. 2005;16(6):349- 360. doi:10.1155/2005/385768

3.24 Salmonella Species Microbiology review for the USMLE Step 1 Exam Salmonella are gram-negative bacteria that cause gastrointestinal disease. They have flagella that enable them to move around and infect cells, and can live inside macrophages. There are two categories of salmonella species: typhoidal and non-typhoidal. Typhoidal salmonella, such as salmonella typhi, cause typhoid fever and are usually acquired through contaminated water. Non-typhoidal salmonella, such as salmonella enteritidis, are usually acquired through contaminated poultry or reptiles. Typhoidal salmonella cause high fever and a pink spotted rash, while non-typhoidal salmonella cause diarrhea, nausea, and vomiting. Both types of salmonella require large quantities of bacteria to make you sick, and supportive care is usually all that is required. Fluoroquinolones like ciprofloxacin are the go-to antibiotics for typhoidal salmonella.      

Nursing considerations for patients taking antibacterial medications. 

Learn more about Dr. Hugh Wegwerth and his services on:SEE VIDEO ON YOUTUBE~  https://www.youtube.com/watch?v=AAzA4n6zigsSchedule a 20-minute Discovery call Send me a voice message if you have a questions Website: https://dochugh.com/ Doc Hugh Check out my Facebook Page: Visit my YouTube Channel00:00:00] Hi community, this is doctor Hugh Wegwerth[00:02:00] Floxed [00:02:15] they put me on Bactrim, which is another antibiotic[00:02:20] I was prescribed Levaquin[00:02:45] it was it was crazy[00:02:55] I had no energy to feed yourself.[00:03:15] it was just such a shocker that what just suddenly happened[00:03:50] struggle was the gut[00:04:05] And I literally I lost like 17 pounds[00:04:25] panic attack before[00:04:35] confusion[00:04:40] you probably heard this from every Floxed person went to like three different doctors.[00:05:30] know, I'm not imagining this. This is happening with other people[00:06:30]  I really loved about for me and I think it's been a major part of even my healing with you is your attitude[00:06:55] there is hope, like you say, there's hope[00:07:10] I decided to go with the program[00:08:10] But like nobody asked me to do those tests[00:08:20] you also get clarity[00:08:45] real and simple.[00:09:15] gluten thing[00:09:35] HCL Challenge[00:10:13] Ups and downs,[00:10:20] I really started seeing major changes[00:11:05] consuming my energy[00:11:25] you're so vibrant[00:11:50] I know. I remember telling you initially I had weird I had developed phobias[00:12:00] would be like, I'm scared of travel.[00:13:09] What to think about pain. Almost unthinkable pain[00:13:15] ringing in your ears and stuff like that.[00:13:45] It's like an earthquake kind of going on inside your body[00:14:05] I don't have vibrations anymore. No cloudiness. [00:14:30] no vibrations anymore[00:14:46] Yeah. Wow. That's that almost makes you want to cry. Be honest with you. I'm holding back tears [00:14:55], there's so many people that are suffering needlessly that aren't getting the advice that they need.[00:15:30] I still I just love you as a doctor[00:15:40] somebody to guide[00:16:05] I did a lot of stuff. I tried acupuncture, I tried energy healing. I mean, you don't know, like, I was going nuts and and I was like, please just help me find something that's going to help my condition.[00:16:20] I'm a spiritual being, your spiritual  person,[00:16:40] The spirit, the power is in your body, heals your body. We just got to figure out what's interfering with that body's ability to heal and function.[00:17:00] low blood, blood pressure[00:17:15] you told me something really simple, like salt water[00:17:45] this Floxed just have like so many issues[00:17:50] so weird like and sometimes, you know, you, you just feel weird sensations throughout your body like you and you have no name for it. You're just like, I don't know. [00:18:00] And that's why they think that they're crazy because you have so many weird neurological problems. They just say it's you're crazy here1[00:18:40] I think my stomach is so much better

Learn more about Dr. Hugh and his services on:Schedule a 20 minute Discovery call https://www.doc-hugh.com/schedule-your-discovery-call  Send me a voice message if you have a question https://www.speakpipe.com/Doc_Hugh_Send_Me_A_Message Website: https://dochugh.com/Facebook Page: https://www.facebook.com/DrHughWegwerth YouTube: https://www.youtube.com/channel/UCujM4lCEXQ5PeOxZMg-_E7Qhttps://www.doc-hugh.com/fluoroquinolone-toxicityIn today's episode we will be talking about Mitochondria, how it works and function, go in depth on it and know how it affects your brain and how you can get better. How it works [1:05] This drug goes for the DNA of the bacteria. This the new classification of these medications of fluoroquinolones, they work in a whole different mechanism, they actually affect the bacterial DNA.[2:21] The DNA of the bacteria is its blue print the new mechanism directly attacks this bacterium and destroys the whole thing.  Mitochondria [2:37] Mitochondria is the power house of the cell, it does a lot of intercellular communication. [5:05] Within one single cell, one single nerve cell, you have one nucleus with all your human DNA. And then within that one cell you have anywhere between 15 to 2000 mitochondria.  Fluoroquinolones Toxicity[5:43] It goes after the DNA and affects DNA replication. [7:00] When you take these antibiotics, it completely destroys your mitochondria because it gets in the mitochondria. And then it sees all it sees all this DNA replication.  It's not going to produce energy optimally; it's not going to die. Effect[7:57] This is why you go to the doctor and you can have all these weird symptoms, neurological symptoms, Achilles tendon problems, brain fog, brain fatigue, fatigue, depersonalization, all these things can occur to you. Because it actually affects every single cell in your body that has mitochondria and within the mitochondria.  

This episode covers fluoroquinolones!

Fluoroquinolones are a type of antibiotic that is an important part of a physicians prescribing arsenal. However, they do carry with them some serious side effects and according to a new study published in the journal, Clinical Infectious Diseases, fluoroquinolones are commonly prescribed for conditions when antibiotics are not needed at all, or when they are not the recommended first-line therapy. Joining me to talk about fluoroquinolones and the study's findings is infectious disease physician and friend of the show, Steven LaRosa, MD.

This week we discuss some critical pearls and teaching points from our morning report conference. https://media.blubrry.com/coreem/content.blubrry.com/coreem/Podcast_Episode_125_0_Final_Cut.m4a Download One Comment Tags: Fluoroquinolones, Pneumonia, Spleen Show Notes FOAMCast: Episode 17 – The Spleen! Read More