Podcasts about Mast cell

Dr. Sandra Kaufmann is back for round two. She's the creator of the Kaufmann Protocol, author of three books on the science of aging, and a longevity physician. In addition to her clinics in Miami and Las Vegas, she also runs Club Exosome, a quarterly gathering of longevity fanatics she calls a modern French salon.This is a conversation for anyone who wants to understand not just what to take, but also why and how to think about longevity at a level that actually moves the needle.— Episode Chapter Big Ideas (timing may not be exact) —0:00 — Intro2:49 — Club Exosome: what it is and why she calls it a French salon3:29 — What she still believes from round one and what she's added 4:30 — Heterochromatin distribution: her new DNA obsession 5:30 — Why circadian rhythms are strictly biochemical 6:32 — Mast cells: why they increase with age and why that matters7:48 — Iron toxicity: the silent accumulator nobody talks about9:05 — Clean bloodwork but still at risk: how iron hides in your tissues10:06 — The plague theory: why your ancestors' iron storage may be killing you slowly12:09 — How to actually test for tissue iron accumulation12:57 — Why giving iron to older patients with low blood iron is often the wrong call13:39 — Aspirin as an iron chelator: the colon cancer connection15:06 — High intensity exercise and iron recycling16:25 — Natural chelators: wheatgrass, quercetin, astaxanthin, aspirin17:31 — Blood donation as a longevity tool, especially for men on testosterone18:28 — Hematocrit and stroke risk19:09 — Exosomes: what they are and how they work at the cellular level 20:57 — Where exosomes come from and why source matters 22:52 — When to start using exosomes and how they compare to PRP 25:26 — Exosomes vs. stem cells: the key differences and why she prefers exosomes 27:43 — Exosomes as an amplifier 28:52 — Mast cells beyond allergies: the aneurysm and heart attack connection 30:26 — What mast cell degranulation is actually doing to your collagen 31:29 — Being allergic to stress: the cortisol-mast cell receptor connection32:01 — Natural mast cell stabilizers 38:48 — Estrogen for men: why trying to eliminate it is a bad idea40:14 — The estrogen algorithm she's building and what it will cover43:37 — Glycation vs. glycan age: what's the actual difference44:36 — HbA1c and skin autofluorescence as glycation markers45:43 — Epigenetic clocks: interesting data, limited decision-making value47:26 — Her actual assessment framework: what labs she starts with 48:01 — Grail liquid biopsy vs. full body MRI: why she wants both51:31 — Tests she wishes existed: sirtuin levels and intracellular NAD51:56 — Sirtuin hierarchy: which ones matter most and what activates them56:06 — Her current pharmaceutical stack and why1:03:37 — The question she's trying to answer next— Connect With Dr. Sandra Kaufmann —Website: https://kaufmannlongevity.com Instagram: https://www.instagram.com/kaufmannlongevity Book1: The Kaufmann Protocol: Why We Age and How to Stop It — https://www.amazon.com/Kaufmann-Protocol-Why-Age-Stop/dp/0692089047/Book 2: The Kaufmann Protocol: Aging Solutions — https://www.amazon.com/dp/B0B5MVFBVQBook: Kaufmann Longevity Treatise Series, Volume 1: Mastering the Mast Cell — https://www.amazon.com/Kaufmann-Longevity-Treatise-Mastering-Mast-ebook/dp/B0GSX7BXL1— Connect with Julian and Executive Health —LinkedIn — https://www.linkedin.com/in/julianhayesii/X — https://x.com/thejulianhayesDon't let your biology become the bottleneck to the enterprise you're building. Book a private call —https://www.executivehealth.io/contact***DISCLAIMER: The information shared is not meant to treat or diagnose any condition. This is for educational, informational, and entertainment purposes. The content here is not intended to replace your relationship with your doctor and/or medical practitioner. Consult your provider before making any decisions.

Summer can bring unique challenges for people living with Mast Cell Disease. From heat and travel to outdoor activities, how can you enjoy the season while managing symptoms? Join us as we sit down with content creator and patient advocate, Jenna Gestetner, to share practical tips for navigating summer with confidence. Resources to keep you in the know:Mast Cell Disease SocietyFAACT's Allergy SummitJennaXHealthInstagram: JennaXHealthTikTok: JennaXHealthYouTube: JennXHealthLinkedIn: Jenna GestetnerYou can find FAACT's Roundtable Podcast on Apple Podcasts, Pandora, Spotify, Podbay, iHeart Radio, or wherever you listen to podcasts.Follow us on Facebook, Instagram, BlueSky, Threads, LinkedIn, Pinterest, TikTok, and YouTube.Sponsored by: Blueprint MedicinesThanks for listening! FAACT invites you to discover more exciting food allergy resources at FoodAllergyAwareness.org!

In this episode of the IRH Clinician's Corner, we're presenting a special panel discussion from our recent Clinical Success Showcase event in January. Host Kristin Whitaker is joined by a powerhouse panel of master practitioners as they break down what histamine intolerance really means, why symptoms like skin issues, gut problems, brain fog, and anxiety are showing up more frequently in practice, and how the world around us might be fueling this trend. You'll learn the spectrum of histamine-related disorders, the known drivers behind these conditions—from chronic infections and toxic exposures to hormonal swings and even trauma—and, most importantly, practical, foundational strategies to help calm symptoms, restore balance, and support your clients or yourself. In this interview, we discuss:   The critical role mast cells and histamine play in immune function, inflammation, and symptom development. How to recognize the often-overlooked symptom patterns associated with histamine intolerance and mast cell activation. Why these conditions are becoming increasingly common and the environmental and lifestyle factors that may be contributing. The powerful relationship between histamine, estrogen, and hormone-related symptom flares throughout a woman's cycle. The most common root causes driving histamine-related symptoms Practical tools for calming the histamine response, supporting recovery, and helping clients expand their diets with confidence. The Clinician's Corner is brought to you by the Institute of Restorative Health. Follow us: https://www.instagram.com/instituteofrestorativehealth/   This episode is brought to you by the Clinical Success Showcase, happening June 1–4 from the Institute of Restorative Health.  Join practitioners from across the industry for four free days of real clinical case studies, expert panels, and practical conversations designed to help you think more systematically and confidently in practice. From pediatric eczema and mood concerns to male hormones, complex chronic cases, and optimizing outcomes for clients on GLP-1 therapies, each session is built around real-world application you can actually use with clients. The Clinical Success Showcase is proudly brought to you by LeadCalculators, Evexia Diagnostics, MRT: A Superior Approach to Managing Diet-Induced Inflammation, and BetterBloodTest.com.  Register free and save your spot today. Timestamps:  00:00 Preview of histamine intolerance panel 09:22 Discussing oncology nutrition certification 14:17 Understanding symptom increase factors 20:25 Discussing mysterious symptoms and triggers 23:14 Understanding histamine intolerance 27:42 Balancing complexity and simplicity in health 33:28 Chronic inflammation and hormones discussion 40:06 Explaining the histamine bucket analogy 45:22 Managing food sensitivities and fear 54:18 Discussing antihistamine trial periods 59:02 Knowing when to refer clients 01:01:23 Advice for new health practitioners 01:10:05 Managing Histamine Intolerance Symptoms 01:14:01 Discussing mast cell stabilizers 01:17:47 Engaging with the panel discussion Speaker bios:  Ellen Lovelace, MPH, FNTP, MRHP is a Master Restorative Health Practitioner and faculty member at the Institute of Restorative Health who brings nearly 20 years of experience in public health and functional nutrition. Sara Fields, FNTP, MRHP is a Master Restorative Health Practitioner and faculty member at the Institute of Restorative Health who specializes in gut health, fertility, and helping clients uncover the root causes of chronic health concerns. Min Kim, NTP, MRHP is a Master Restorative Health Practitioner who helps clients uncover root causes, interpret complex health patterns, and create practical nutrition strategies that support long-term wellness. Keywords:  Clinician's Corner, functional health, histamine intolerance, mast cell activation syndrome, MCAS, mast cell disorders, root causes, gut health, autoimmune conditions, mental health, sleep issues, hormone fluctuations, perimenopause, menopause, estrogen dominance, chronic inflammation, mold exposure, long covid, chronic infections, GI MAP test, Dutch Test, MRT food sensitivity test, DAO enzymes, low histamine diet, antihistamines, H1 blockers, H2 blockers, nervous system support, dietary strategies, trauma and health, client intake forms Disclaimer: The views expressed in the IRH Clinician's Corner series are those of the individual speakers and interviewees, and do not necessarily reflect the views of the Institute of Restorative Health, LLC. The Institute of Restorative Health, LLC does not specifically endorse or approve of any of the information or opinions expressed in the IRH Clinician's Corner series. The information and opinions expressed in the IRH Clinician's Corner series are for educational purposes only and should not be construed as medical advice. If you have any medical concerns, please consult with a qualified healthcare professional. The Institute of Restorative Health, LLC is not liable for any damages or injuries that may result from the use of the information or opinions expressed in the IRH Clinician's Corner series. By viewing or listening to this information, you agree to hold the Institute of Restorative Health, LLC harmless from any and all claims, demands, and causes of action arising out of or in connection with your participation. Thank you for your understanding.  

Your relationships are reshaping your biology in ways that diet and exercise alone cannot fix, and the science behind it will change how you think about longevity, metabolism, and what it actually means to be healthy. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Molly Maloof, a physician and one of the most innovative voices in personalized medicine, functional medicine, and human performance. Since 2012, she has advised or consulted for over 50 companies across digital health, consumer health, and biotechnology. She pioneered a course on healthspan at Stanford University and founded Adamo Bioscience, a company dedicated to unlocking the science of love as a pathway to healing and human connection. Dr. Maloof brings a rare combination of clinical depth, biohacking credibility, and entrepreneurial range to one of the most overlooked conversations in longevity. Together, Dave and Dr. Maloof dig into the neurobiology of love and attachment, the hormonal drivers of the sex drive and pair bonding, and how chronic isolation wrecks your metabolism at the cellular level. They explore the cell danger response and how toxic relationships, mold exposure, and trauma can lock your cells into a self-protection mode that blocks healing. They also cover psychedelics as hormetic tools, oxytocin as nature's medicine, the placebo response, peptide therapy for mitochondrial repair and anti-aging, and why regenerative medicine is about to rewrite the rules of human lifespan. If you are serious about biohacking your body from the inside out, this episode is essential. You'll Learn: Why human connection is a biological necessity, not a lifestyle preference, and what isolation does to your mitochondria and metabolism How the three neurobiological drives of sex, romantic love, and attachment are wired into your hormones and what happens when they go wrong What the cell danger response is, why it gets stuck, and which peptides, supplements, and therapies help break the cycle How oxytocin drives wound healing, immune function, and the placebo response Why psychedelics work as hormetic love drugs and how they reproduce the neurobiology of romantic love The top peptides for mitochondrial repair, brain optimization, and telomere biology Why Dave and Dr. Maloof believe we have already reached longevity escape velocity How AI is accelerating precision medicine, protein folding breakthroughs, and the future of anti-aging therapeutics Why fasting, breathwork, neurofeedback, and somatic therapies all converge on the same biological reset mechanism How to build the adaptive capacity and bioenergetic reserves to bounce back from anything Thank you to our sponsors! - Danger Coffee | Grab yours at DangerCoffee.com and use code DAVEPOD at checkout for 15% off. - Amp | If you're ready to make fitness fit into your life, go to amp.ai to check it out - Puori | Go to Puori.com/DAVE or use code DAVE at checkout to get 32% off your Puori Fish Oil subscription. You save more than $18 - Our Place | Stop cooking with toxic cookware and upgrade to Our Place today. With a 100-day risk-free trial, plus free shipping and returns, you can experience this game-changing cookware with zero risk. Visit: fromourplace.com/DAVE Use code: DAVE for 10% off sitewide Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dr. Molly Maloof, Adamo Bioscience, Stanford University, personalized medicine, functional medicine, healthspan, longevity, biohacking, human performance, anti-aging, regenerative medicine, longevity escape velocity, cell danger response, mitochondria, mitochondrial health, oxytocin, vasopressin, dopamine, serotonin, neurobiology of love, attachment theory, pair bonding, sex drive, hormone replacement therapy, testosterone, estrogen, menopause, andropause, libido, female sexual dysfunction, relationship biology, social health, isolation, community, co-regulation, trauma healing, psychedelics, MDMA, psilocybin, ibogaine, ayahuasca, hormetic stress, social hormesis, neurofeedback, 40 Years of Zen, breathwork, nervous system regulation, HPA axis, cortisol, mast cell activation, histamine, long COVID, mold exposure, phospholipid therapy, glutathione, vitamin C, BPC-157, TB500, SS31, epothilone, SELANK, SEMAX, BDNF, telomere biology, telomerase, peptides, GLP-1, placebo response, wound healing, metabolism, continuous glucose monitoring, gut health, AI, precision medicine, supplements, brain optimization, neuroplasticity Resources: • Grab Molly's Book The Spark Factor: https://www.amazon.com/Spark-Factor-Supercharging-Optimizing-Feeling/dp/0063207206 • Learn More About Dr. Molly's Work: https://drmolly.co/ • Visit Your Healthspan Journey: https://yourhealthspanjourney.mystrikingly.com/ • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:28 – Intro 01:39 – COVID Isolation & Its Effects 03:11 – Science of Love & Hormones 04:24 – Psychedelics & Love Chemistry 09:22 – Cell Danger Response 11:07 – AI, Tech & Human Connection 13:20 – Social Connection as Medicine 20:50 – Placebo, Care & Psychedelics 24:49 – Altered States & Healing Modalities 30:09 – Peptides & Longevity Drugs 35:44 – Mast Cell & Personal Health Challenges 43:46 – Regenerative Medicine & The Future 46:17 – Longevity Escape Velocity 50:05 – Outro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your cells start failing at 35. Dr Sandra Kaufmann reveals the 7 systems breaking down — and how to stop it. Your cells start failing at 35. Dr Sandra Kaufmann reveals the 7 systems breaking down — and how to stop it.

When your symptoms shift daily and no one, not even your doctor, can give you clear answers, the hypervigilance can feel like the only rational response. But what if that constant scanning is actually making your nervous system harder to calm, and there's a way to work with it instead of against it?In this episode, you'll hear from Dr. Amanda Whitehouse, licensed psychologist specializing in anxiety and trauma related to food allergies and mast cell conditions. She reframes nervous system regulation not as a reset button, but as a slow, trust-building process, and explains why that distinction matters more than most people realize.Connect with Destiny:  Instagram / Facebook / Website______________________________

Ready to find out why you can't sleep and get a step-by-step, customized plan to fix it? Schedule a consultation to get started with the Complete Sleep Solution program: https://p.bttr.to/3VJwvDsOver the years working with people who struggle with chronic insomnia, I started noticing a pattern. Some clients who wake up around 2 or 3am often experience things like sudden anxiety at night, temperature changes, skin symptoms, or a racing heart. And those symptoms often point to something most sleep advice never talks about.In this episode, I'll walk you through:How mast cell activity and histamine can wake your body up in the middle of the nightWhy it often happens around 3:00 AMHow to calm mast cells so you can stay asleep00:00 Why You Wake at 3AM01:06 A Client Pattern Emerges01:56 Immune System Not Stress02:04 Quick Program Break02:39 Mast Cells Explained03:30 Histamine as Wake Signal04:14 Why It Peaks Overnight04:44 Menstrual Cycle Connection05:02 What You Can Do05:22 Dinner and Histamine Foods05:59 Calm Your Nervous System06:25 Supplements for Histamine07:08 Fix the Root Causes07:41 Wrap Up and Next Steps

In this episode of the Healing Powers Podcast, host Laura Michelle Powers speaks with medical doctor and functional medicine expert Dr. Kelly McCann about mast cell activation syndrome (MCAS), histamine intolerance, and the growing number of people experiencing unexplained chronic symptoms. Although mast cell activation was only first described in medical literature in 2007, research suggests that up to one in five people may be affected.Dr. McCann explains how mast cells—an important part of the immune system—can become overly reactive due to environmental toxins, mold exposure, infections, stress, and trauma. When this happens, it can trigger widespread inflammation throughout the body and lead to symptoms such as allergies, brain fog, digestive issues, insomnia, migraines, anxiety, and fatigue. Laura also shares her own experiences with mold exposure and sensitivities, highlighting how many people struggle to get answers through conventional testing.Learn more about Dr. Kelly McCann at thespringcenter.com As Dr. Kelly referenced, you can find more information and locate mold-aware professionals through the International Society for Environmentally Acquired Illness (ISEAI): https://iseai.org/Kelly K. McCann, MD, MPH is a triple board-certified physician in Internal Medicine, Pediatrics, and Integrative Medicine, with additional certifications in Functional Medicine and Medical Acupuncture. She is the founder of The Spring Center in Costa Mesa, California, where she specializes in complex chronic illness, including Mast Cell Activation Syndrome, mold and mycotoxin illness, Lyme disease, and environmentally acquired conditions.Dr. McCann has hosted multiple international summits on MCAS and allergy-related illness and serves on the boards of the American Academy of Environmental Medicine and was a founding Board member of the International Society for Environmentally Acquired Illness. A graduate of Tulane University School of Medicine and one of only 35 physicians worldwide to complete the residential fellowship at the University of Arizona's Center for Integrative Medicine, she also holds a Master's in Spiritual Psychology.Her work is now evolving into what she calls The Unforgetting Project: a new healing paradigm that bridges functional medicine with spiritual psychology, inviting patients to experience symptoms not as failures, but as meaningful messages guiding them back to wholeness.Laura is a Celebrity Psychic who has been featured by Buzzfeed, The Weakest Link, Beast Games, NBC, ABC, CBS, FOX, the CW, Motherboard by Vice Magazine and the #1” Ron Burgundy Podcast” with Will Ferrell. Laura Powers is a clairvoyant, psychic medium, writer, actress, producer, writer, and speaker who helps other receive guidance and communicate with loved ones. Laura travels nationally and internationally for clients, events, television appearances, and speaking engagements. She is also the author of 7 books on the psychic realm and 1 book on podcasting. Laura also works as a psychic, entertainer, and creative entrepreneur.For more information about Laura and her work, you can go to her website www.healingpowers.net or find her on X @thatlaurapowers, on Facebook at @realhealingpowers and @mllelaura, and on Instagram, TikTok and Insight Timer @laurapowers44.

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Why do so many Lyme patients stay sick — even after treating infections, detoxing, and “doing everything right”?In this episode of Integrative Lyme Solutions, Dr. K sits down with functional and environmental medicine pioneer Dr. Kelly McCann to explore why Lyme disease, mold toxicity, and Mast Cell Activation Syndrome (MCAS) are rarely just infections — and why true healing requires addressing the terrain of the body, nervous system, emotions, and spirit. Drawing from her own journey through mold illness and Lyme disease, Dr. McCann explains how immune dysregulation, trauma, limbic system activation, and cell membrane damage keep patients stuck in chronic illness.This conversation dives deep into mast cell activation, mold exposure, Bartonella, phosphatidylcholine therapy, biofilms, nervous system regulation, emotional trauma, spirituality, and why symptoms are not betrayals — but messages. If you've been gaslit, dismissed, or feel like your body is working against you, this episode offers validation, insight, and a radically different way to understand Lyme healing.Key Takeaways:0:00 Introduction and Dr. Kelly McCann's personal healing journey3:00 Mold exposure as a hidden driver of chronic illness6:20 Lyme, Bartonella, and the overlap with mast cell activation9:30 Why siloed medicine fails complex chronic disease patients11:40 Phosphatidylcholine and cell membrane repair explained13:50 When antimicrobial treatment stalls, look beyond infections16:50 Mast cell activation, trauma, and nervous system dysregulation18:40 The limbic system's role in chronic illness21:10 Emotional trauma, immune boundaries, and people-pleasing24:00 Language, identity, and separating yourself from disease26:10 Terrain theory and why healing requires self-honoring choices29:00 Illness as an invitation, not a punishmentResources Mentioned:Dr. Kelly McCann – https://drkellymccann.comThe Spring Center – https://thespringcenter.comThe Unforgetting Project – https://unforgettingproject.comMicroGen DX (Next Generation Sequencing) – https://microgendx.comByron White Formulas – https://byronwhiteformulas.com _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email info@TheKarlfeldtCenter.comCheck out Dr. K's Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

In this episode of Derms and Conditions, host James Q. Del Rosso, DO, welcomes Lauren Madigan, MD, associate professor of dermatology at the University of Utah, for a focused exploration of mast cell disease, an often underrecognized but clinically significant group of disorders that dermatologists may encounter on the front lines. The conversation begins with mast cell biology, including their origin in the bone marrow, tissue-specific phenotypes, and roles beyond classic allergic disease. Dr Madigan explains how mast cells contribute to immune defense and wound healing, with Dr Del Rosso noting how infrequently they are discussed in routine dermatology training despite their relevance across multiple conditions. They then explore mastocytosis across the age spectrum, contrasting pediatric presentations (many of which remit by adolescence) with adult-onset disease, where cutaneous findings often signal systemic involvement. Dr Madigan reviews current National Comprehensive Cancer Network guidance, emphasizing that most adults presenting with cutaneous mastocytosis will have some degree of systemic disease and may warrant more detailed testing for accurate staging, prognostic differentiation, and management choices. The discussion highlights the heterogeneity of systemic mastocytosis, from indolent forms to advanced disease with organ involvement or associated hematologic neoplasms. The episode also covers practical diagnostic and workup considerations, including laboratory evaluation, KIT mutation testing, and biopsy considerations. Dr Madigan stresses the importance of experienced dermatopathology interpretation and thoughtful site selection to optimize diagnostic yield. Treatment strategies are discussed through a pragmatic lens, ranging from symptom-directed therapies to cytoreductive and targeted tyrosine kinase inhibitors, with an emphasis on individualized care based on disease subtype, symptomatology, and prognosis. The episode closes with resources to help dermatologists navigate diagnostic assistance and treatments via specialty centers and clinical trials. Listen to the episode to deepen your understanding of mast cell disease, sharpen your diagnostic approach, and gain practical guidance on evaluation, staging, and management strategies, both for real-world practice and for determining when referral to specialized care is warranted.

What if the random symptoms you've been told are "all separate" – the hives, exhaustion, brain fog, and digestive chaos – are actually ALL connected through one dysfunctional system in your body that affects 1 in 5 people? When Dr. Tania Dempsey left traditional medicine after being told she wouldn't get bonuses for patients with cholesterol over 200, she discovered something revolutionary: conditions like fibromyalgia, chronic fatigue, long COVID, and mysterious autoimmune markers might all trace back to the same source: dysfunctional mast cells. In this conversation, Dr. Dempsey reveals why your mast cells (your body's security guards) might be stuck in overdrive, leaking over 1,200 different inflammatory chemicals throughout your body. She explains why perimenopausal women and adolescents are hit hardest, how hormones trigger these cellular explosions, and why that positive thyroid antibody test might not mean what you think. Most shocking? The conventional medical system's approach of treating symptoms separately might be exactly what's keeping you sick. Dr. Dempsey shares her personalized protocol that's helping patients reclaim their lives, but warns that you can't supplement your way out of this without addressing one crucial system everyone overlooks. If you've been gaslit by doctors, told your labs are "normal" despite feeling terrible, or you're navigating mysterious symptoms that worsen with hormonal changes, this conversation will help everything make sense.   Catch the full episode on YOUTUBE HERE: https://bit.ly/MidlifeConversationsYouTube    Learn More About Dr. Tania Dempsey   Instagram ➜ https://www.instagram.com/drtaniadempseymd  Website ➜   https://drtaniadempsey.com/    Thank you to our show sponsors! TIMELINE: Timeline is offering 20% off your order of Mitopure! Go to https://timeline.com/NATALIEJILL Free Gifts for being a listener of Midlife Conversations! Mastering the Midlife Midsection Guide: https://theflatbellyguide.com/ Age Optimizing and Supplement Guide: https://ageoptimizer.com   Connect with me on social media! Instagram: www.Instagram.com/Nataliejllfit Facebook: www.Facebook.com/Nataliejillfit   For advertising inquiries: https://www.category3.ca/  Disclaimer: Information provided in the Midlife Conversations podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before making any changes to your current regimen.  Information provided in this podcast and the use of any products or services related to this podcast does not create a client-patient relationship between you and the host of Midlife Conversations or you and any doctor or provider interviewed and featured on this show. Information and statements may have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease. Advertising Disclosure: Some episodes of Midlife Conversations may be sponsored by products or services discussed during the show. The host may receive compensation for such advertisements or if you purchase products through affiliate links. Opinions expressed about products or services are those of the host and/or guests and do not necessarily reflect the views of any sponsor. Sponsorship does not imply endorsement of any product or service by healthcare professionals featured on this podcast.  

Mast Cell Activation Syndrome (MCAS) is one of the most misunderstood drivers of chronic inflammation, fatigue, and hypersensitivity. In this episode, I break down what MCAS actually is, why it develops, and how to stabilize it. You'll learn the full physiological sequence behind mast cell activation, the real triggers: mold, infections, hormones, trauma… and how to restore regulation through nervous system work, nutrients, and drainage. This episode is science-heavy, systems-based, and practical,  everything you need to finally understand what's happening in your body.   Hosted by Leanne Vogel.   Root Cause Group Coaching program: https://p.bttr.to/3SqUExb    Coaching and other supports available at: https://shop.healthfulpursuit.com/    Podcast Sponsors, links and offers available at: https://www.healthfulpursuit.com/podcast/  Bioactive Peptides: https://www.healthfulpursuit.com/make

Clonal mast cell disease is often missed because symptoms vary from person to person, tryptase levels can be normal, and bone marrow biopsies are hard to get. For some people, unexplained or very severe anaphylaxis may be an early sign of a clonal mast cell disease. In this episode, we review “Prevalence of KIT D816V in anaphylaxis or systemic mast cell activation,” published in October 2025 in the Journal of Allergy and Clinical Immunology. This paper, known as the PROSPECTOR trial, is looking at how often the KIT D816V mutation can be found using a blood test in adults who have had anaphylaxis or systemic mast cell activation symptoms. We break down why KIT D816V matters, how it connects to systemic mastocytosis, why HaT needs to be considered, and how newer blood tests may help doctors catch clonal mast cell disease earlier. What we cover in our episode about KIT D816V and anaphylaxis: Setting the stage: Understanding mast cell activation and anaphylaxis. Why KIT D816V matters: How this mutation fits into clonal mast cell disease, what blood testing can reveal, and when doctors still turn to a bone marrow biopsy. Making sense of tryptase and hereditary alpha-tryptasemia (HaT): Why baseline tryptase, the “20% + 2” rule, and HaT can make screening more complicated than it seems. What the PROSPECTOR trial uncovered: How often KIT D816V appeared in people with anaphylaxis, and other results on tryptase and HaT. How this helps patients: What these findings mean for anyone with unexplained or severe anaphylaxis, and how doctors combine KIT testing, tryptase, HaT, and symptoms to decide on next steps. Other podcast episodes about mast cell disease: Ep. 127: Management of indolent mastocytosis - A clinical yardstick Ep. 126: Management of mast cell activation syndrome - A clinical yardstick Ep. 121: Avapritinib vs Placebo in Indolent Systemic Mastocytosis - PIONEER Trial Ep. 118: The ISM Disconnect - Do Patients and Providers Agree on Symptom Control? Ep. 70 How do stress and low histamine diets impact mast cell disease? Ep. 63: Mast Cell Diseases & Systemic Mastocytosis: The Basic Science Ep. 65: The Symptoms and Triggers of Mast Cell Disease *********** The Itch Review, hosted by Dr. Gupta, Kortney, and Dr. Blaiss, explores allergy and immunology studies, breaking down complex research in conversations accessible to clinicians, patients, and caregivers. Each episode provides key insights from journal articles and includes a one-page infographic in the show notes for easy reference. *********** Made in partnership with The Allergy & Asthma Network. Thanks to Blueprint Medicines for sponsoring today's episode.  This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Living with Mast Cell Activation Syndrome (MCAS) requires constant awareness and preparation—but what happens when you hit the road or board a plane? We're joined by content creator and patient advocate, Jenna Gestetner, who's sharing her top strategies and favorite tips for traveling safely and confidently with MCAS. Resources to keep you in the know:Mast Cell Disease SocietyFAACT's Allergy SummitJennaXHealthInstagram: JennaXHealthTikTok: JennaXHealthYouTube: JennXHealthLinkedIn: Jenna GestetnerYou can find FAACT's Roundtable Podcast on Apple Podcasts, Pandora, Spotify, Podbay, iHeart Radio, or wherever you listen to podcasts.Follow us on Facebook, Instagram, BlueSky, Threads, LinkedIn, Pinterest, TikTok, and YouTube.Sponsored by: ARS PharmaThanks for listening! FAACT invites you to discover more exciting food allergy resources at FoodAllergyAwareness.org!

On this episode Lara and Vyanka talk to Dr Frank Siebenhaar from the Charité University Hospital Berlin all about mast cell disorders. This is ImmunoTea: Your Immunology Podcast, presented by Dr Lara Dungan and Dr Vyanka Redenbaugh. This is the show where we tell you all about the most exciting research going on in the world of immunology. So grab a cup of tea, sit down and relax and we'll fill you in. Contact us at ImmunoTeaPodcast@gmail.com or @ImmunoTea on twitter. Hosted on Acast. See acast.com/privacy for more information.

It could be a bug bite. Or a harmless fatty lump. But it might be a mast cell tumor. In this episode of the VetFolio Voice podcast, we delve into mast cell tumors in dogs, including the unpredictable nature of these tumors, nuances around interpretation of cytology and histopathology reports, cytologic grading accuracy, and options for therapy including surgery, chemo, radiation and Stelfonta, an injectable mast cell tumor treatment for dogs. You'll learn about staging considerations and the role of newer prognostic panels as well as strategies for client communication about mast cell disease.

In this enlightening conversation, Dr. Kelly McCann discusses the significance of mast cell activation syndrome and its growing prevalence in today's world. She explores the intricate connections between environmental toxins, autoimmune diseases, and emotional well-being, emphasizing the importance of holistic approaches to health. Dr. McCann shares her personal journey through health challenges and highlights the need for awareness regarding mold exposure and detoxification. The discussion also touches on the impact of midlife transitions on purpose and joy, encouraging listeners to reconnect with their true selves and speak their truth for better health. Time Stamps: (00:29) Understanding Mast Cell Activation Syndrome (06:29) The Link Between Autoimmune Diseases and Mast Cells (08:43) Allergies: The Role of Maternal Exposure (11:39) The Interconnection of Mind, Body, and Spirit (18:11) Midlife Transitions and Purpose (21:22) Dr. McCann's Journey to Holistic Medicine (25:39) Understanding Lyme Disease and Mold Exposure (28:41) The Impact of Environmental Factors on Health (30:51) Mold and Weight Loss Resistance (33:59) Detoxification as a Key to Weight Loss (37:20) Testing for Toxic Substances (41:23) The Connection Between Truth and Health (48:28) The Unforgetting Project: Embracing Joy and Purpose ------------------- Website: https://drkellymccann.com Instagram: https://www.instagram.com/drkellymccann/ Instagram: https://www.instagram.com/thespringcenter/ Facebook: https://www.facebook.com/drkellymccann/ ------------------- Instagram: https://www.instagram.com/carolcovinofitness/ -------------------- My YouTube Channel: http://youtube.com/@carolcovinofitness -------------------- My Book: FINDING PURPOSE IN THE PAUSE

Dr. Brooke Britton discusses degranulation events—a scary potential when a dog has mast cell tumors. Learn what degranulation is, why it happens, and how it can affect your dog. Also: practical tips for managing symptoms, potential connections between allergies and cancer, and how to care for dogs with mast cell tumors. Topics Discussed: • What is a degranulation event? • How mast cell tumors cause degranulation • Symptoms dogs may experience during a degranulation event • The role of allergies and chronic inflammation in mast cell tumor risk • Medications and treatments to manage symptoms • Low-histamine diets and their role in comfort care • Tips for preventing future mast cell tumor growth • The importance of early detection and regular vet check-ups Your Voice Matters! If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question. Related Videos: https://www.youtube.com/watch?v=Al7jjCXVhuE https://www.youtube.com/watch?v=6eb4GrcH_f8 Related Links: Our article on mast cell tumors: https://www.dogcancer.com/articles/types-of-dog-cancer/mast-cell-tumors-in-dogs/ Chapters: 00:00 Introduction 01:15 What Are Mast Cell Tumors? 02:30 The Role of Mast Cells in Normal Immune Response04:00 What Happens During a Degranulation Event?06:45 Symptoms Dogs May Experience During Degranulation09:00 How Dogs Might Feel During Degranulation Events11:00 Stomach Upset and Ulcers in Dogs with Mast Cell Tumors13:00 The Link Between Allergies and Mast Cell Tumors16:00 Managing Allergies in Dogs to Reduce Risk18:30 Diet Considerations: Low-Histamine and Commercial Diets22:00 Medications for Degranulation Symptoms: Benadryl and Tagamet25:00 The Truth About Diet and Cancer Prevention27:30 Why Balanced Diets Are Key for Dogs with Cancer29:45 Closing Thoughts on Degranulation and Mast Cell Tumors34:00 Outro: Support and Resources for Dog Owners Get to know Dr. Brooke Britton: https://www.dogcancer.com/people/brooke-britton-dvm-dacvim-oncology/    For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices

About our guest:Kimberley Quirk is a lead practitioner at Mast Cell 360, blending deep clinical insight with a nurturing approach and her own lived experience through healing. She works closely with clients to map out practical, step-by-step plans that honor each person's unique pace and sensitivities.Free haywire mast cell quiz:https://mastcell360.com/mystery-quiz/MastCell360 website:https://mastcell360.com/home/ Instagram:https://www.instagram.com/mastcell360/?hl=enStephanie's links:Tiktok: https://www.tiktok.com/@drstephpeacockInstgram: https://www.instagram.com/drstephpeacock/Work with me: https://stephaniepeacock.com/ Subscribe to my newsletter: https://stephanies-newsletter-c410d1.beehiiv.com/subscribe

In this special Ask Me Anything episode of The Art of Being Well, Dr. Will Cole and his clinical team tackle your most pressing health questions - from whether food sensitivities like an avocado reaction really mean you can never eat it again, to the surprising science behind hydrogen-rich water, to what “natural flavors” actually hide (spoiler: you'll never guess one of them). They also dive into practical mast cell activation support, navigating chronic illness plateaus, the keto diet for insulin resistance, and actionable tools for calming your nervous system. Plus, learn how Dr. Cole's team uses listener voice messages in AMA episodes, and how you can submit yours for a future show. For all links mentioned in this episode, visit www.drwillcole.com/podcast.Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Sponsors:Use my link to give the new AG1 flavors a try, plus a FREE Welcome Kit: drinkag1.com/willcole. Text ABW to 64000 to get twenty percent off all IQBAR products, plus FREE shipping. Message and data rates may apply.Reverse hair loss with @iRestorelaser! Subscribe & Save for 25% off or more + free shipping on the iRestore REVIVE + Max Growth Kit, and unlock HUGE savings on the iRestore Elite with the code WILLCOLE at https://www.irestore.com/WILLCOLE!Strong Cell comes in a daily 2 oz drink, and I challenge you to take it for 30 days and see how you feel. Go to strongcell.com/will today to get started. Friends of the show get 20% off.Practice love every day with Paired, the #1 app for couples. Download the app at http://www.paired.com/beingwell.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Are your symptoms being brushed off as “just anxiety” when you know something deeper is going on? If you've been told your labs are “normal,” but your body feels anything but — you're not alone. So many people with complex, overlapping symptoms like fatigue, GI issues, dizziness, brain fog, and medication sensitivities are stuck in a loop of misdiagnosis and dismissal. And it's exhausting. In this episode of the Concussion Nerds Podcast, Dr. Zachary Spiritos — neurogastroenterologist and founder of Ever Better Medicine — pulls back the curtain on two highly misunderstood and underdiagnosed conditions: POTS (Postural Orthostatic Tachycardia Syndrome) and Mast Cell Activation Syndrome (MCAS). These aren't “rare unicorn” illnesses — they're just rarely understood.

Influencer, content creator, and founder of xHealth Studio, Jenna Gestetner, shares how she tackles sharing her personal health information while fulfilling her goal of helping others. Jenna authentically shares her life with Mast Cell Activation Syndrome (MCAS), Postural Orthostatic Tachycardia Syndrome (POTS), food allergies, and autoimmune disorders.Resources to keep you in the know:JennaXHealthInstagram: JennaXHealthTikTok: JennaXHealthYouTube: JennXHealthLinkedIn: Jenna GestetnerYou can find FAACT's Roundtable Podcast on Apple Podcasts, Pandora, Spotify, Podbay, iHeart Radio, or wherever you listen to podcasts.Follow us on Facebook, Instagram, BlueSky, Threads, LinkedIn, Pinterest, TikTok, and YouTube.Sponsored by: ARS PharmaThanks for listening! FAACT invites you to discover more exciting food allergy resources at FoodAllergyAwareness.org!

Send us a textThis is Part 1 of an update on Mast Cell Activation in Long Covid. I talk about the symptoms, causes and the various diagnoses of Long Covid MCAS. In Part 2 I talk about the management, treatments and outcomes.I am Dr Tim Robinson, formerly a GP for 30 years, retired as planned at the start of the Covid pandemic. Since then I have become involved in the world of Long Covid. Currently I am GP clinical lead for three NHS Long Covid Services in South West England - Dorset, Bristol and South Devon. I am also Clinical Lead for Hope for the Community CIC. I have research involvement as co-investigator in a study on breathlessness in Long Covid, University of Bristol.Long Covid Doctor is an educational series for Long Covid sufferers; each talk covers the many aspects of Long Covid, the symptoms, causes, treatments, management and expected outcomes.Episodes are found on:Apple PodcastsSpotifyGoogle PodcastsYouTubeTranscripts of the individual episodes are available on YouTube as well as:www.LongCovidDoctor.comEpisodes are accessed on:TwitterFacebookInstagramLinked inDisclaimer: Long Covid Doctor is an educational series. Any advice, diagnosis, treatments mentioned should only be considered after discussion with your own GP or qualified professional health provider.Links, resources:NICE Covid-19 rapid guideline:https://www.nice.org.uk/guidance/ng188/chapter/5-ManagementHow to manage post viral fatigue after Covid-19:https://www.rcot.co.uk/how-manage-post-viral-fatigue-after-covid-19-0

Send us a textThis is Part 2 of an update on Mast Cell Activation in Long Covid. I talk about the management, treatments and outcomes of Long Covid MCAS. In Part 1 I talked about the symptoms and causes of Long Covid MCAS.I am Dr Tim Robinson, formerly a GP for 30 years, retired as planned at the start of the Covid pandemic. Since then I have become involved in the world of Long Covid. Currently I am GP clinical lead for three NHS Long Covid Services in South West England - Dorset, Bristol and South Devon. I am also Clinical Lead for Hope for the Community CIC. I have research involvement as co-investigator in a study on breathlessness in Long Covid, University of Bristol.Long Covid Doctor is an educational series for Long Covid sufferers; each talk covers the many aspects of Long Covid, the symptoms, causes, treatments, management and expected outcomes.Episodes are found on:Apple PodcastsSpotifyGoogle PodcastsYouTubeTranscripts of the individual episodes are available on YouTube as well as:www.LongCovidDoctor.comEpisodes are accessed on:TwitterFacebookInstagramLinked inDisclaimer: Long Covid Doctor is an educational series. Any advice, diagnosis, treatments mentioned should only be considered after discussion with your own GP or qualified professional health provider.Links, resources:NICE Covid-19 rapid guideline:https://www.nice.org.uk/guidance/ng188/chapter/5-ManagementHow to manage post viral fatigue after Covid-19:https://www.rcot.co.uk/how-manage-post-viral-fatigue-after-covid-19-0

This episode was recorded at the 2025 Florida Ruminant Nutrition Symposium.  Dr. Baumgard begins with an overview of his presentation, “Importance of gut health to drive animal performance and health.” He notes the metabolic and inflammatory fingerprint of all stressors is essentially the same, indicating they likely all emanate from the gut. Overall, we're gaining a better understanding of how typical on-farm stressors negatively influence gut barrier function. He thinks the most likely mechanism of leaky gut is the immune cell known as a mast cell. When an animal or human is stressed, the enteric nervous system releases corticotropin-releasing factor, which binds to the mast cell, the mast cell degranulates, and the former contents of the mast cell (TNF-alpha, proteases, histamine, etc.) causes the gut to become leaky. (4:20)Once the GI tract barrier becomes compromised, antigens like lipopolysaccharide (LPS) can infiltrate, stimulating the immune system. Immune activation causes loss of appetite much like any other infection. The gut heals fairly quickly upon removal of the stressor(s), and the gut can also acclimate to stress such that the early stages of a stress event are more severe than later stages. Strategies to combat leaky gut remain scarce, and there is no silver bullet. There are a variety of dietary strategies to target the gut permeability issue itself. Another approach would be to bind pathogens or curb their proliferation at the membrane of the small intestine. (7:06)Dr. Neiehues asks if an antihistamine would work on gut mast cells the way it does in other body systems. Dr. Baumgard isn't sure that's ever been looked at, although there have been some studies in pigs using a product targeted to prevent mast cell degranulation. Dr. Nelson wonders if we should interfere in some of these processes because they're obviously there for a reason. Panelists discuss stress events related to parturition and transition, particularly for first-calf heifers. Dr. Baumgard notes that stacking stressors on top of one another compromises an animal's ability to tolerate stress. (9:28)We know stress can cause ulcers in humans and horses - what about ruminants? Dr. Baumgard thinks it is likely that it's happening, but we aren't looking for it. Few animals who die on-farm do receive a thorough postmortem exam. It could also be that these types of insults to the gut are not visible to the naked eye. (19:11)Dr. Nelson asks what makes some cows, despite all the challenges, able to be up and milking 150 pounds a day in no time after calving. What makes them unique? Dr. Baumgard lists some possibilities, including lower pathogenic inflammation than other cows, less tissue trauma damage to the uterus during calving, and lower sensitivity to immune activation. The panel disagrees with the notion that high-producing cows are stressed. (23:16)Dr. Niehues and Dr. Baumgard trade stories of experiments where cows maintained production even with high stress and inflammatory markers. The panel goes on to discuss subclinical infections and their impact on transition cows. Dr. Nelson notes there are retrospective datasets where cows who had metritis showed decreased feed intake even before calving. Dr. Baumgard feels that the decrease in intake has been incorrectly assumed to be the cause of the metritis. He says the decrease in intake is often around two weeks before calving and he doesn't think it's a coincidence that at the same time, the mammary gland is initiating lactogenesis. He hypothesizes the mammary gland is causing an immune response, resulting in a decrease in intake. Dr. Nelson wonders if measuring somatic cell counts of colostrum would show any differences in mammary gland inflammation during this prepartum period. (29:18)Panelists share their take-home thoughts. (42:02)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt. 

Send us a textIt's the end of June, and I'm wrapping up our listener-powered Q&A series with a jam-packed solo episode. I tackle three big questions from Sarah, Jeanine and Wendy that span swollen fingers after COVID, mast-cell mayhem, bumps around the eyes, fertility prep, and even rheumatoid arthritis. Thanks for being here! KEY TAKEAWAYS:Swollen Fingers Post-COVID: Often linked to cellular stress, mineral imbalances (esp. low potassium), and mast cell activation. Support adrenals and mineral status first.Mast Cell & Eczema: Consider nervous system inputs (EMDR, breathwork, stress history), liver drainage, and gentle anti-inflammatory support like Holy Basil.Fertility Prep: Focus on mitochondrial support, nutrient repletion, progesterone monitoring, and nervous system regulation at least 3 months preconception.Skin Bumps Around Eyes: Often tied to liver sluggishness and drainage issues. Use face mapping as a tool; consider low-level toxin load and mineral depletion.RA vs. OA: RA = immune dysfunction; assess food reactivity (e.g., nightshades), gut health, and family toxin exposure. OA = structural; consider regenerative injections (e.g., prolozone).Family Symptom Clusters: Think environmental—evaluate for mold, radon, or metals (e.g., uranium on HTMA). Toxic burden may explain “mystery” symptoms.Rate • Review • Reach OutLove these quick-fire case breakdowns? Share the episode, leave a review on Apple Podcasts, and drop your next burning question here https://www.christabiegler.com/questions and I might answer it on air after our July 4th hiatus.See you in July, Christa

We're diving into the world of mast cell diseases, equipping you with the knowledge and tools to navigate this condition. Whether you're a patient, healthcare professional, or a caregiver, this conversation, led by Jessica Fraser, Executive Director of the Mast Cell Disease Society, will guide you on how to find resources, support, and community. Resources to keep you in the know:The Mast Cell Disease SocietyWhat Are Mast CellsEmergency Room Response Plan Find a Physician CME OpportunitiesPatient Guides and Tool Kits Support Groups You can find FAACT's Roundtable Podcast on Apple Podcasts, Pandora, Spotify, Podbay, iHeart Radio, or wherever you listen to podcasts.Follow us on Facebook, Instagram, BlueSky, Threads, LinkedIn, Pinterest, TikTok, and YouTube.Sponsored by: Blueprint MedicinesThanks for listening! FAACT invites you to discover more exciting food allergy resources at FoodAllergyAwareness.org!

Mast cell activation syndrome isn't widely recognized, but for many women, it may explain years of pain, fatigue, and hormone related chaos no one could solve.I see a lot of patients who are struggling with fatigue, pain, and hormone symptoms that don't seem to make sense on paper. And I've noticed a pattern but I wanted to talk to someone who lives in the complexity of it every day.Dr. Tania Dempsey, is one of the few physicians who's helped bring mast cell activation syndrome (MCAS) into the spotlight. Years ago, she was treating a patient who just wasn't getting better until she stumbled on a paper about mast cells that changed everything. That one article led to a phone call, a new way of thinking, and a career shifting collaboration with one of the leading voices in the field.In this conversation, we explore how MCAS shows up in gynecology especially in cases involving PCOS, perimenopause, and unexplained pelvic pain. We discuss why some patients are unusually sensitive to progesterone, how inflammation fuels insulin resistance, and what's actually going on when mast cells become overactive. We also get into the clinical triad so many of us see MCAS, hypermobility, and POTS and how they often appear together in patients who are struggling to get answers.Tania also talks about how she built her practice by spending more time listening to her patients and trusting that their symptoms meant something, even when the labs didn't show it. Highlights:What mast cells do and how they become overactive in MCAS.The overlooked link between PCOS, perimenopause, and mast cell dysfunction.Why some patients react badly to progesterone—and what to do about it.How GLP-1 drugs like Ozempic may help calm inflammation in MCAS.What to know before seeking a diagnosis or starting treatment.If this episode opened your eyes or gave you language for what you've been going through, please subscribe, leave a review, and drop a comment. I'd love to hear what resonated most with you.Dr. Dempsey's Bio:Dr. Tania Dempsey, MD, ABIHM is a world-renowned expert in complex, multisystem diseases. As founder of the AIM Center of Personalized Medicine, in Purchase, NY, Dr. Dempsey uses functional and integrative medicine to get to the patient's root cause(s) of illness and to help them find a path to optimum health. Her extensive knowledge and experience with Mast Cell Activation Syndrome, Mold, and Lyme and other Vector-Borne Diseases, has propelled her to the forefront of the medical community as a recognized and trusted speaker, researcher, advocate, and physician.Dr. Dempsey is Board-Certified in Internal Medicine and Integrative and Holistic Medicine. She received her MD degree from The Johns Hopkins University School of Medicine and her BS degree from Cornell University. She completed her Internal Medicine Residency at NYU Medical Center.She was recently elected to the Board of Directors of ILADS (International Lyme and Associated Diseases Society). She is also a member of the U.S. ME/CFS Clinician Coalition, the American Academy of Ozonotherapy, and ISSWSH (International Society for the Study of Women's Sexual Health).She is an accomplished international speaker, writer and thought leader and has 8 peer-reviewed articles in the medical literature. Her latest endeavor is cohosting the new podcast, Mast Cell Matters.Get in Touch with Dr. Dempsey:WebsiteFacebookInstagram

Join Dr. Troy on Synapse SNPS as he welcomes Mackenzie to the podcast. In this powerful episode, Mackenzie bravely shares her personal experience living with mast cell disorder. Hear firsthand about the challenges, the search for answers, and the steps she's taken on her path towards healing and reclaiming her health. If you or someone you know is navigating complex health issues, Mackenzie's story offers valuable insight and hope.

In this episode of the Spectrum of Health podcast, Dr. Christine Schaffner shares key insights from her recent presentations at leading health conferences. She explores the growing recognition of mast cell activation as a major health issue and highlights the innovative role of peptides and exosomes in treatment. Dr. Schaffner also discusses the significance of addressing cancer stem cells and the deeper root causes behind mast cell activation, offering a forward-thinking perspective on healing and clinical care. For the full show notes please visit my website: https://www.drchristineschaffner.com/Episode286  

Join Dr. Troy Spurrill and PA Richelle Voth with guest expert Bryanna Gregory, PharmD, RPh, for a focused discussion on the latest in mast cell and the Independent Medical Alliance (IMA). Explore Dr. Gregory's resources: https://www.bryanagregory.com/

An episode that explores the intricate connections between MCAS, autism, and POTS through a neurodivergent lens and the principles of functional medicine. Jess Lewis joins Matt and Angela to share her personal journey, the impact of medical gaslighting, and practical strategies for mast cell stabilization.Here's what's in store for today's episode: * In today's episode, we explore the link between MCAS and autism with special guest Jess Lewis — a functional medicine and trauma-informed neurodiversity advocate who supports individuals living with MCAS.* Jess talks about how getting COVID and being around mold kicked her mast cells into overdrive.* When our bodies are under too much stress, a dysregulated nervous system can send our mast cells into overdrive. Since autistic people are being forced to navigate a neurotypical world, we are more prone to this.* We delve into the experience of medical gaslighting and the struggle to access supportive care while living with MCAS.* Additionally, we discuss the importance of a low-histamine diet when managing MCAS and how it can play a key role in reducing symptoms.* Our hosts and Jess explore the connection between POTS and autism, and share strategies for calming and stabilizing overactive mast cells.* We then dive into the topic of anaphylaxis and how it can occur when mast cells become severely dysregulated. Jess breaks down what happens in the body during an anaphylactic response — and how, in those with MCAS, even seemingly minor triggers can lead to a cascade of symptoms when the immune system is already in a heightened state of alert.* Finally, we explore the intersection of practical and functional medicine, and how blending both approaches can offer more comprehensive support for those with complex conditions like MCAS.“When you go to the doctor, think about it like a work meeting. Have a plan, have an agenda, have the questions laid out. Use your superpowers of deep research. Bring studies - not to be combative, but just to say, ‘I wanna colaborate on this. Here's what I'm seeing, here's what I'm thinking. And if your doctor doesn't wanna listen to you, go find another doctor. Feel good about the boundaries you put in front of yourself, because you gotta advocate.” - Jess Lewis“If I can change one mind, I can change several minds… If I could change things for just a few people to have the lightbulb go off, to say, ‘I've got your back. I want to be the advocate for you. I want you to be the advocate for yourself.” - Jess LewisDid you enjoy this episode? We took a deep dive into the intersection of MCAS, autism, and neurodivergent health experiences. From medical gaslighting to the overlap with POTS and nervous system dysregulation, we unpack what it means to live in a body that's constantly on high alert. We also explore the importance of functional medicine, low-histamine diets, and practical strategies for mast cell stabilization. Join the convo with #AutisticCultureCatch!Jess Lewis (she/they) is a Chief Technology Officer, turned MCAS researcher, and founder of the Mast Cell Support community. After reversing her own severe case of MCAS triggered by COVID and mold exposure, Jess now helps others heal using an evidence-based, neurodivergent-friendly approach rooted in functional medicine and trauma-informed care. She's currently pursuing a PhD in Functional Medicine with a specialty in Mast Cell health and comorbidities, and brings a deep, systems-thinking lens to both her health advocacy and her continued leadership in tech.Show NotesThreads, Instagram, Substack: @jesslewisAdditional info and links: https://subscribepage.io/jesslewisjesslewis.comCommunity - https://community.mastcellsupport.com/invitationFood Guide Pharmacyhttps://en.wikipedia.org/wiki/QuercetinRelated Episodes:Autistic Medical Needs (Episode 14)Meat Body Maintenance (Episode 53)Autistic Medical Needs, Part 2 (Episode 108)Follow us on InstagramFind us on Apple Podcasts and SpotifyLearn more about Matt at Matt Lowry, LPPJoin Matt's Autistic Connections Facebook GroupLearn more about Angela at AngelaKingdon.com Angela's social media: Twitter and TikTokOur Autism-affirming merch shop This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.autisticculturepodcast.com/subscribe

“If you have a new onset of anxiety or depression that doesn't even make sense to you, think of a more physical cause.” - Dr. Neil Nathan   Do you have issues with focus, concentration, or even finding the word you want to use? If so, you might be dealing with the hidden effects of mold toxicity and Lyme disease.  In this episode, Dr. Aimie sits down with Dr. Neil Nathan to discuss how mold toxicity and Lyme disease can create a "biology of threat" in the body that can trigger and maintain a state of hypervigilance and reactivity. This is not the only issue  mold toxins and Lyme infections can cause. They can create unique inflammatory responses that affect the brain, nervous system, and immune function, often manifesting as unexplained anxiety, depression, cognitive issues, and physical symptoms that are often misdiagnosed as mental health disorders. Dr. Nathan also introduces "the big three" factors keeping the body stuck in threat mode: limbic activation, vagal dysregulation, and mast cell activation. He'll share how these become dysregulated when faced with mold toxicity and Lyme disease, causing the body to shut down as a protective mechanism. This explains why you may experience seemingly inexplicable sensitivities and reactions despite doing all the "right" emotional and psychological work for trauma recovery. Join them as they break down the science behind the body's response to mold toxicity and Lyme disease, if it's possible to reverse it, and actionable steps you can take to start the healing journey. You'll learn more about: [05:05] How “out of the blue” anxiety, depression, or other symptoms might actually be caused by mold or Lyme [10:00] What makes the inflammation associated with these internal stressors unique [16:46]  Why the “big three” need to be addressed together in sensitive patients [17:38] How mold toxicity and Lyme can lead to chronic neurological and autoimmune conditions [20:33] The internal trauma response that can be created by mold toxicity and Lyme And more!   Dr. Neil Nathan is a Board Certified Family Physician who has been practicing medicine for over 50 years. As he studied and learned a wide variety of alternative concepts, his practice gravitated into primarily helping to diagnose and treat those patients who have not been helped by conventional medicine. He's worked with thousands of patients with complex medical illnesses such as fibromyalgia, chronic fatigue, mold toxicity, chronic Lyme disease, autism, and chronic pain.    Related Podcasts: Episode 105: How Anxiety, Depression & Trauma Reactions May Be From Mold and Heavy Metals Episode 106: How Mast Cell Activation, Histamines & Mold Toxicity Place You in a High-Risk Trauma Category   Guides, Tools & Resources: The Essential Sequence - free guide that shows you the difference between stress and trauma states of our nervous system. In just 3 steps, it walks you through what your body needs when it has stored trauma or is in a freeze response. Foundational Journey - a guided 6 week journey into your inner world with a structured sequence of somatic and parts interventions with live online classes. One of the things that happens in just the first 21 days of the Foundational Journey is that people experience a 26% decrease in daily physical pain, speaking to what Dr Schubiner was just talking about, these neural secret pains, can turn off and on, and it's not actually necessarily due to the the injury the body itself. It is a neural circuit and we're managing the pain just by working with the nervous system, looking at the habitual component of it and continuing with essential parts work.   Connect with Dr. Neil Nathan: Website   Disclaimer: By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others. Consult your own physician for any medical issues that you may be having. This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Trauma Healing Accelerated, any guests or contributors to The Biology of Trauma® podcast, or any employees, associates, or affiliates of Trauma Healing Accelerated be responsible for damages arising from the use of the podcast. Comment Etiquette: I would love to hear your thoughts on this episode! Please share your constructive feedback by using personal name or initials so that we can keep this space spam-free, and let's keep the discussion positive!  

If your body is super reactive… even the tiniest change can set off awful symptoms – then you should consider the spectrum of mast cell activation diseases.What most people find enjoyable, like healthy foods, exercise, or even sunlight, can make some feel horrible. Often these symptoms are beyond just “histamine intolerance symptoms.”And while others around you might think you're just “being dramatic” or “making a mountain out of a molehill,” it's clear to you that your body is extremely more reactive than others.It can be hard to get a clear diagnosis and help if you are struggling with mast cell activation diseases – including those with hypermobility syndrome issues like Ehlers-Danlos.If your life feels like you're constantly navigating a minefield of unexpected symptoms to the smallest things, I'm joined by Michelle Shapiro, RD, to talk about what causes you to have a “highly sensitive body.”Michelle Shapiro, RD is an Integrative/Functional Registered Dietitian in NYC who has helped over 1000+ clients reverse their anxiety, heal long-standing gut and immune issues, and approach their weight in a loving way. Michelle has a virtual private practice of 5 nutritionists where she and her team work one-on-one towards these goals. She is the host of the Quiet the Diet Podcast, where she helps listeners bridge the gap between body positivity and functional nutrition.If you've been searching for answers about your own body's unpredictable reactions or want to better understand these complex conditions, let's dive in!In This Episode:What's a “highly sensitive body” problem (that you'll be stuck with forever)?The role of mast cells as “guards” of your immune systemHistamine intolerance symptoms (and why a histamine intolerance diet doesn't help long-term)Histamine intolerance versus Mast Cell Activation DiseasesThe surprising link between MCAS, POTS, and hypermobility syndromeWhy POTS isn't a heart problemThe long COVID–histamine intolerance connectionPractical tips for managing symptoms histamine intolerance symptomsQuotes“Highly sensitive bodies often react in ways we don't expect—things that are supposed to be good for you, like healthy foods or exercise, can make you feel worse.”“Histamine issues don't just cause rashes or itchy skin; they can trigger severe insomnia, anxiety, and even psychosis.”LinksFind Michelle online | InstagramMichelle's podcast, Quiet the DietMichelle's Highly Sensitive Body Hub WaitlistHealthy Skin Show ep. 319: Mast Cell Activation Syndrome: What is MCAS + Why It's So DevastatingHealthy Skin Show ep. 166: Mold + Histamine ConnectionReady to figure out your skin's root causes so you can finally fix your skin + break free from meds to manage your skin?My virtual clinic works with adults worldwide struggling with eczema, psoriasis, rosacea, urticaria, hives, dandruff, perioral dermatitis + more.Trusted by over 1000 clients, we get results WITHOUT restrictive elimination diets.Schedule an assessment call at https://skinrepaircall.com/

Have you ever wondered why you are so reactive - to people, foods, smells, sounds and stress - while other people around you seem completely fine? Y ou are going in overdrive or even going into overwhelm, and think you just must be having a bad day or looking for what triggered you.  The answer might surprise you. A specific cell of your immune system, mast cells, could be actually causing trauma responses in your body, putting you into emotional states, that have less to do with the people around you and more with a compound those cells release, histamine.   Today we're tackling a commonly overlooked underlying reason for anxiety. We will be answering the question, How do mast cell activation and mold toxicity keep us stuck in our responses and triggers to trauma? Before we dive in, I want to dedicate this episode to the loving memory of our guest Beth O'Hara, who passed away in July 2024.  Beth was a pioneering functional naturopath who transformed countless lives through her work with Mast Cell 360, helping people understand and heal from complex cases of Mast Cell Activation Syndrome (MCAS), mold toxicity, and related conditions. She was a friend to me and I am sad to not have more time and conversations with her. In this episode, you'll discover: How to recognize if histamine is driving your anxiety  Why mold exposure can keep your body stuck in trauma responses long after exposure How mast cells bridge your immune system and emotional overwhelm Why and how mast cells will block your ability to create inner safety  Practical tools to decrease reactivity and build resilience For more information and show notes, please visit our website: https://biologyoftrauma.com/biology-of-trauma-podcast/

Are you or someone you love struggling with mysterious, multi-system symptoms—ranging from skin rashes and digestive issues to migraines and unexplained fatigue? You might have been searching for answers but keep hitting dead ends. If you've ever wondered if these diverse and seemingly unrelated symptoms could be connected, it might be time to consider Mast Cell Activation Syndrome (MCAS). MCAS is a condition that affects up to 20% of the population, yet it remains underdiagnosed and misunderstood. In today's episode, I'll be walking you through the ins and outs of MCAS, from how it's diagnosed to the practical steps you can take for treatment. If you're feeling frustrated by traditional medicine's inability to connect the dots on your health issues, this episode will provide some much-needed clarity. Let's explore how MCAS could be the missing link in your health journey and what you can do about it. Key Points: What is MCAS and Why It's Misunderstood MCAS is a multi-system inflammatory condition affecting various parts of the body, causing symptoms like skin rashes, digestive issues, and fatigue. Often misunderstood, MCAS can go undiagnosed for years as patients seek answers from multiple specialists. Dr. Dempsey's Journey to MCAS Expertise Dr. Tanya Dempsey shares her personal journey into recognizing MCAS in her patients, explaining how her curiosity and persistence led her to uncover MCAS as a common, yet often overlooked condition affecting many of her patients. How MCAS is Diagnosed: Laboratory Markers and Clinical Features Diagnosing MCAS requires looking at specific clinical features and laboratory markers. Blood and urine tests can reveal mast cell mediators, while biopsies from gastrointestinal scoping procedures can show elevated mast cells in tissue samples. This segment discusses the complexities and difficulties in obtaining a definitive diagnosis. The Role of Triggers in MCAS Identifying triggers is crucial in managing MCAS. Dr. Dempsey explains how some triggers can be environmental, while others may be internal, making them difficult to pinpoint. Understanding your specific triggers is key to effective treatment. Treatment Options for MCAS: Antihistamines and Beyond The first line of treatment often includes antihistamines—both H1 and H2 blockers. This segment covers how trial and error is often needed to find the right combination for each individual. Natural options like Vitamin C and quercetin are also explored, offering listeners alternatives to pharmaceutical interventions. Living with MCAS: Individualized Treatment Approaches One size does not fit all when it comes to managing MCAS. Dr. Dempsey highlights the importance of a personalized approach, where patients must try different treatments systematically to find what works for them. The need for patience and persistence in the journey to wellness is emphasized. Mast Cell Activation Syndrome might be the missing piece in your complex health puzzle. Whether you're dealing with unexplained chronic symptoms or feeling frustrated by a lack of answers, understanding MCAS could bring you closer to relief. The key takeaway from today's episode is that while diagnosing and treating MCAS can be challenging, it is possible—and it starts with understanding your body's unique triggers. With a combination of personalized treatments, patience, and persistence, you can regain control of your health. If any of this sounds familiar, I encourage you to explore MCAS further and, if necessary, find a practitioner knowledgeable in its diagnosis and treatment. Let's continue this journey toward better health—one piece of the puzzle at a time. How to Connect Dr. Tania Dempsey Dr. Tania Dempsey is a world renowned expert in chronic disease, autoimmune disorders, and mast cell activation syndrome, and is sought after internationally for her knowledge of chronic immune dysregulation. As founder of the AIM Center of Personalized Medicine, Dr. Dempsey uses functional and integrative medicine to get to the patient's root cause(s) of illness, understand why people get sick, help patients understand their body, and understand why it fails them when it does. She works with patients all over the United States, as well as from places around the world such as Israel, England, Thailand, and France. AIM Center for Personalized Medicine: https://drtaniadempsey.com/ How to Connect with Dr. Meg: Women's Wellness Collective: www.megmill.com/collective. use code HEALTH to get your first month 1/2 off Apply to work 1:1 with Dr. Meg: HERE Free Guide: Unraveling the Mystery: Understanding Mast Cell Activation Syndrome for simple steps and protocols you can start today to improve your gut health. You can also follow along on Instagram @drmegmill for daily health tips! Website: www.megmill.com  This content is for educational purposes only and should not be taken as medical advice. Always consult with a healthcare professional before starting any new diet or exercise program.

While high histamine levels are a very real health issue, histamines themself are not the root cause of your symptoms...     While high histamine levels may be responsible for skin rashes, digestive problems, itchiness, headaches, fatigue, brain fog, and more, true relief requires addressing the underlying imbalances causing the elevated histamines in the first place.     So join me on today's Cabral Concept 3238 as we uncover the root cause of histamine imbalances and explore actionable steps you can take to restore balance. Enjoy the episode, and I'd love to hear your feedback!   - - - For Everything Mentioned In Today's Show: StephenCabral.com/3238 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Dr. Fiona Lovely is a longevity, health and wellness expert with specialties in menopause medicine, functional neurology and functional medicine.  She is speaking to the topics of women's health around perimenopause and menopause.   Today, Dr. Lovely welcomes Dr. Meg Mill back to the show to discuss a very contemporary health concern - mast cell activation and the role of histamine and histamine intolerance.  Whether you are a headache sufferer, have experience long haul symptoms from covid infection or shots, have questionable gut health or have mysterious symptoms that no one seems to help with, you will want to listen in.   If you are the person who feels like you have a reaction to EVERYTHING (including water), this episode is for you! Want Dr Meg's histamine guide - she references it in the show?  Please visit histamine guide here.  You can find out more about Dr Meg Mill at her website and on IG @drmegmill Thank you to our sponsors for this episode:

In this episode of the Accrescent podcast, host Leigh Ann welcomes Dr. Steph Peacock to discuss mold toxicity, its impact on health, and effective ways to heal from it. Dr. Peacock shares her journey from being a competitive swimmer to her focus on holistic medicine, particularly mold toxicity and mast cell activation syndrome. They delve into the connection between concussions and mold susceptibility, the significance of nervous system regulation, and the importance of addressing one's environment. Dr. Peacock highlights the need for proper testing and treatment, including environmental assessment, mycotoxin panels, binders, and gut motility support. The conversation also covers additional detoxification methods and the role of emotional and physical stressors on overall health.Product Discount Codes + LinksFall SkincareHerbal Face Food: The Serum IIHerbal Face Food Discount Code: LAL20Facial Lounge: Facial in a Bottle NightFacial Lounge Discount Code: LEIGHANNHoneybee Hippie: Honey Hydrate Tallow BalmHoneyBee Hippie Discount Code: LEIGHANN10Micro Balance HealthMicro Balance Health: WebsiteMicro Balance Health Code: ACCRESCENTBuoy ElectrolytesBuoy: Website (link gives 20% discount)Work w/Leigh AnnLearn: What is EVOX Therapy?Book: Schedule a Session or FREE Discovery CallMembership: What is The Uplevel Lab?Interview LinksBook Club: Now FREE, Join the Group Today!Book Club: Link if You Are NOT A Member of the Uplevel LabBook Club: Link if You ARE a Member of the Uplevel LabProduct: Ermi Dust TestProduct: Immunolytics TestLearning: Nervous System: Accrescent Podcast Episodes on the Nervous System: 147, 140, 115, 105, 104Product: Activated Charcoal: My Favorite Activated Charcoal (discount code: LEIGHANNLINDSEY)Product: Infrared Sauna:

Welcome back, Dr Rachel Venable, DVM, MS, DACVIM (oncology) to the podcast! This week we discuss mast cell tumors!I don't know about you... but I always get confused about current guidelines with MCT. They can be anything from low-grade removal and no sweat... to multiple high-grade panic! How much margin do you really need? When is Stelfonta an option? Check out all this great conversation all about MCTs and how to approach them from a boarded oncologist!TIMESTAMPSIntro 00:00Predispositions To Mast Cell Tumors 01:08Single Mast Cell Tumors 02:25Multiple Mast Cell Tumors 08:30Are Subcutaneous Mast Cell Tumors More Of A Concern? 13:54Staging Mast Cell Tumors 15:18An Overview Of Stelfonta 17:36Outro 20:10

Immune discusses two stories of immune cells eating other cells: microglia engulfing brain neurons to shape cortical development and behavior, and mast cells trapping neutrophils to increase their functional and metabolic fitness. Hosts: Vincent Racaniello, Cindy Leifer, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Microglia shape cortical development and behavior (Cell) Neutrophil trapping by mast cells (Cell) Time stamps by Jolene. Thanks! Music by Steve Neal. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv

Closing chapters, Diabetes, Cholesterol, Mast Cell, & Vitamin D! Your body heals itself and Janet knows how to engage all corners of that super power! Achieve full immunity and follow JANET ON IG // FOLLOW @deplorablejanet ON IG&VISIT PARANOIRADIO.COM ☂️ --- Support this podcast: https://podcasters.spotify.com/pod/show/paranoiradiopodcast/support

In this episode, Dr. Linda Bluestein, the Hypermobility MD, delves into the intricate connections between the immune system and hypermobility disorders with Dr. Kara Wada. A quadruple board-certified physician and Sjogren's patient, Dr. Wada shares her expertise on mast cell activation syndrome, autoimmunity, and the role of inflammation. Discover holistic approaches to managing these conditions and gain valuable insights into the latest research and treatments. Don't miss the special hypermobility hacks at the end! Takeaways: Interplay Between Immune System and EDS: The immune system plays a significant role in hypermobility disorders, with conditions like mast cell activation syndrome and autoimmunity frequently seen in patients with EDS. Differences in Allergy and Mast Cell Activation: Allergy involves the immune system's memory of proteins, whereas mast cell activation syndrome can be triggered by various factors, often without the presence of traditional allergies. Inflammation's Role in Chronic Conditions: Chronic inflammation is a core issue in many modern diseases, including EDS and autoimmune disorders. It's the body's prolonged response to injury or infection that can lead to various health issues. Impact of Hormones: Hormones, particularly estrogen and progesterone, significantly influence immune system functioning and can affect conditions like POTS, often seen in EDS patients. Holistic and Lifestyle Approaches: Managing EDS and related conditions can benefit from holistic approaches, including anti-inflammatory diets, regular movement, adequate sleep, and stress management techniques such as meditation and journaling. Connect with YOUR Bendy Specialist, Dr. Linda Bluestein, MD at https://www.hypermobilitymd.com/.   This episode is sponsored by EDS Guardians. If you want to learn more, check them out here: https://www.edsguardians.org/    Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them.

Anaphylaxis, organ failure & common allergies and more! Janet supplies hope and dumps a massive load of information on how to negate this mortal disease and refill your organs, body and mind with the knowledge to combat current Mast Cell Activations. // FOLLOW @DeplorableJanet on Instagram & VISIT US AT PARANOIRADIO.COM ☂️ --- Support this podcast: https://podcasters.spotify.com/pod/show/paranoiradiopodcast/support

Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions:    Lindsey: hi dr. cabral - i have had what seems to be kidney pain for years. i only get relief when my spouse does really deep tissue massages on my lower back. after, my stomach makes gurgling noises and it ends up being gas. ive gone 1 time to a gastro for this and they said it's not my kidneys but inflamed intestines appearing as kidney pain. can you please point me in the right way ?   Katherine: Hi Dr. Cabral, Thank you for all u do! You are my "benchmark" in the health world. Wondering what you would recommend a member of your family if this happened to them. Summer 2022 I had a really bad kidney stone that landed me in the hospital. I passed it. Since then I had about 4 more instances of kidney stones (but not as severe-was able to take some meds to ease the pain until it passed). Recently I went for a CT Scan and it showed my left Ureter dilated. The Urologist suggested another CT scan with dye or a to putna camera in and see if something is there causing a blockage or a tumor. Curious what I can do to be more proactive.   Tina: Love your show :) what is the best alternative to a mammogram? Thermal imaging anything you can recommend please I do not want to go for a mammogram. I've read other women with mast cell activation having breast cancer. Also, really trying hard to get rid of mast cell activation. Is cancer is a sign of mast cell activation ? Alma powder will it help mast cell activation? Alma powder better then berberine? Been researching alternatives to semaglutitde with myself having insulin resistance type 1 diabetes I am full plant based no fat no sugar no salt Please need help   Olivea: Dr. Cabral, The information you provide is wonderful. I just listened to your podcast 'why not fast until lunch' I have never been a huge proponent of fasting for myself simply because of my schedule. Curious what you would recommend for my schedule in regards to fasting and overall health - I try to eat dinner around 6:30/7pm each night. I wake up at 4:45 for the gym - I typically eat an apple on my way to the gym (I go to CrossFit) - my workout is an hour (starting at 5:15am) and then I have 1 egg + some egg whites around 7am, I then make myself a smoothie with water, fruit, and almond milk and take it to work with me and it usually takes me a few hours to drink it. I guess more of what I am asking is - someone who has morning workouts - what do you recommend for fasting?   Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!      - - - Show Notes and Resources: StephenCabral.com/3039 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

In this episode, we sit down with Dr. Grace Liu, the founder of The Gut Institute, to delve into the intricacies of gut health and its paramount importance. She brings her extensive expertise to the table, sharing vital insights on why addressing gut health should be a top priority for overall well-being. Dr. Grace also shares top peptides to use, how to fix leaky gut, the role of different probiotics like Akkermansia, histamine intolerance, and more. Tune in to learn how you can optimize your gut health!Dr. Grace Liu PharmD is an IFM-trained functional medicine practitioner and founder of The Gut Institute. She is a clinical pharmacist with a doctorate in practice for 20+ years and specializes in complex disease management. Dr. Liu consults and helps clients gain optimal performance through rebuilding the microbiome after damage from modern living. She uses nutrigenomic tools and other advanced functional lab testing to give the solutions, strategies and treatments that reverse modern gut dysbiosis and disease. SHOW NOTES:0:51 Welcome to the show!3:55 Dr. Grace Liu's Bio4:27 Welcome her to the podcast!5:43 Why are we still overlooking gut health?7:25 About BPC-157 Peptide8:41 Optimizing the basics first10:45 Vitamin D-Gut Connection11:39 Fixing gut permeability14:58 Addressing parasite exposure16:14 Leaky Gut Procol19:34 Gut testing options23:32 Long COVID Protocols26:32 Do you have a parasite?31:18 AMPs (Peptides) & Probiotics34:53 Benefits of Akkermansia37:19 Mast Cell & Histamines40:47 Adrenal Protocols & markers of stress42:21 Benefits of warmer body temperatures46:23 Binders for supporting detox49:02 Blue Zone diets & dietary starches51:03 Oxalates, yeast & molds55:40 Stimulating oxytocin & vagal tone59:00 Getting drunk off bread1:01:16 Balancing the immune system & histamine overload1:10:42 Where to find her1:12:34 Her final piece of advice1:14:08 Thanks for tuning in!RESOURCES:The Gut Institute - Discount code: BABES10Instagram: Gut_GoddessFacebook: The Gut InstituteYouTube: Dr. Grace LiuPinterest: The Gut InstituteTikTok: Dr. Grace LiuBiOptimizers Magnesium Breakthrough - code: BIOHACKERBABES10 + subscribe to receive free gifts and additional discountsOur Sponsors:* Go to Puori.com/BIOHACKERBABES and use our promo code BIOHACKERBABES for 20% off site wide!Support this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands

Make sure to support this podcast by heading over to Paleovalley.com/NwJ and the 15% off discount will automatically be applied to your first order. _____I'm excited to sit down with Beth O'Hara. We talk about histamines and MCAS, effects of mold in the home environment, and much more. Make sure to listen to the full interview to learn more.Beth O'Hara is a Functional Naturopathic Consultant specializing in complex, chronic cases of Mast Cell Activation Syndrome, histamine intolerance, mold toxicity, and related conditions. She is the founder and clinical director of Mast Cell 360, a functional naturopathy practice designed to address all factors surrounding health conditions – biochemical, physiological, environmental, epigenetic, and emotional wellness.Beth crafted Mast Cell 360 to resemble the practice she wished had existed when she was severely ill with Mast Cell Activation Syndrome, histamine intolerance, mold toxicity, neural inflammation, Lyme, fibromyalgia, and chronic fatigue. Her present mission is to serve as a guiding light for others navigating Mast Cell Activation Syndrome, histamine intolerance, and these related conditions in their healing journeys.We discuss the following:All about Beth O'HaraHistamines and MCASSymptoms of histamine intoleranceTesting for histamine and MCASLong COVID and MCASHow to support the nervous systemThoughts on mast cell stabilizer medicationsSensitivity to DAO supplementsMold's impact on the pancreasEffects of mold in the home environmentSupporting mold illness recoveryHealing from MCASWhere to find Beth O'Hara_____RESOURCESBeth's WebsiteBeth's FacebookHistamine Digest 360 with DAOMast Cell Nervous System Reboot Master ClassNwJ Mind-Body Program____SIGN UP FOR MY WEEKLY NEWSLETTERCHECK OUT MY BOOK, Carnivore CureCHECK OUT MY SECOND BOOK, The Complete Carnivore Diet for Beginners: Your Practical Guide to an All-Meat Lifestyle_____ ADDITIONAL RESOURCESNutrition with Judy ArticlesNutrition with Judy ResourcesNutrition with Judy Podcast_____ FIND ME