Podcasts about Mast cell

An episode that explores the intricate connections between MCAS, autism, and POTS through a neurodivergent lens and the principles of functional medicine. Jess Lewis joins Matt and Angela to share her personal journey, the impact of medical gaslighting, and practical strategies for mast cell stabilization.Here's what's in store for today's episode: * In today's episode, we explore the link between MCAS and autism with special guest Jess Lewis — a functional medicine and trauma-informed neurodiversity advocate who supports individuals living with MCAS.* Jess talks about how getting COVID and being around mold kicked her mast cells into overdrive.* When our bodies are under too much stress, a dysregulated nervous system can send our mast cells into overdrive. Since autistic people are being forced to navigate a neurotypical world, we are more prone to this.* We delve into the experience of medical gaslighting and the struggle to access supportive care while living with MCAS.* Additionally, we discuss the importance of a low-histamine diet when managing MCAS and how it can play a key role in reducing symptoms.* Our hosts and Jess explore the connection between POTS and autism, and share strategies for calming and stabilizing overactive mast cells.* We then dive into the topic of anaphylaxis and how it can occur when mast cells become severely dysregulated. Jess breaks down what happens in the body during an anaphylactic response — and how, in those with MCAS, even seemingly minor triggers can lead to a cascade of symptoms when the immune system is already in a heightened state of alert.* Finally, we explore the intersection of practical and functional medicine, and how blending both approaches can offer more comprehensive support for those with complex conditions like MCAS.“When you go to the doctor, think about it like a work meeting. Have a plan, have an agenda, have the questions laid out. Use your superpowers of deep research. Bring studies - not to be combative, but just to say, ‘I wanna colaborate on this. Here's what I'm seeing, here's what I'm thinking. And if your doctor doesn't wanna listen to you, go find another doctor. Feel good about the boundaries you put in front of yourself, because you gotta advocate.” - Jess Lewis“If I can change one mind, I can change several minds… If I could change things for just a few people to have the lightbulb go off, to say, ‘I've got your back. I want to be the advocate for you. I want you to be the advocate for yourself.” - Jess LewisDid you enjoy this episode? We took a deep dive into the intersection of MCAS, autism, and neurodivergent health experiences. From medical gaslighting to the overlap with POTS and nervous system dysregulation, we unpack what it means to live in a body that's constantly on high alert. We also explore the importance of functional medicine, low-histamine diets, and practical strategies for mast cell stabilization. Join the convo with #AutisticCultureCatch!Jess Lewis (she/they) is a Chief Technology Officer, turned MCAS researcher, and founder of the Mast Cell Support community. After reversing her own severe case of MCAS triggered by COVID and mold exposure, Jess now helps others heal using an evidence-based, neurodivergent-friendly approach rooted in functional medicine and trauma-informed care. She's currently pursuing a PhD in Functional Medicine with a specialty in Mast Cell health and comorbidities, and brings a deep, systems-thinking lens to both her health advocacy and her continued leadership in tech.Show NotesThreads, Instagram, Substack: @jesslewisAdditional info and links: https://subscribepage.io/jesslewisjesslewis.comCommunity - https://community.mastcellsupport.com/invitationFood Guide Pharmacyhttps://en.wikipedia.org/wiki/QuercetinRelated Episodes:Autistic Medical Needs (Episode 14)Meat Body Maintenance (Episode 53)Autistic Medical Needs, Part 2 (Episode 108)Follow us on InstagramFind us on Apple Podcasts and SpotifyLearn more about Matt at Matt Lowry, LPPJoin Matt's Autistic Connections Facebook GroupLearn more about Angela at AngelaKingdon.com Angela's social media: Twitter and TikTokOur Autism-affirming merch shop This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.autisticculturepodcast.com/subscribe

“If you have a new onset of anxiety or depression that doesn't even make sense to you, think of a more physical cause.” - Dr. Neil Nathan   Do you have issues with focus, concentration, or even finding the word you want to use? If so, you might be dealing with the hidden effects of mold toxicity and Lyme disease.  In this episode, Dr. Aimie sits down with Dr. Neil Nathan to discuss how mold toxicity and Lyme disease can create a "biology of threat" in the body that can trigger and maintain a state of hypervigilance and reactivity. This is not the only issue  mold toxins and Lyme infections can cause. They can create unique inflammatory responses that affect the brain, nervous system, and immune function, often manifesting as unexplained anxiety, depression, cognitive issues, and physical symptoms that are often misdiagnosed as mental health disorders. Dr. Nathan also introduces "the big three" factors keeping the body stuck in threat mode: limbic activation, vagal dysregulation, and mast cell activation. He'll share how these become dysregulated when faced with mold toxicity and Lyme disease, causing the body to shut down as a protective mechanism. This explains why you may experience seemingly inexplicable sensitivities and reactions despite doing all the "right" emotional and psychological work for trauma recovery. Join them as they break down the science behind the body's response to mold toxicity and Lyme disease, if it's possible to reverse it, and actionable steps you can take to start the healing journey. You'll learn more about: [05:05] How “out of the blue” anxiety, depression, or other symptoms might actually be caused by mold or Lyme [10:00] What makes the inflammation associated with these internal stressors unique [16:46]  Why the “big three” need to be addressed together in sensitive patients [17:38] How mold toxicity and Lyme can lead to chronic neurological and autoimmune conditions [20:33] The internal trauma response that can be created by mold toxicity and Lyme And more!   Dr. Neil Nathan is a Board Certified Family Physician who has been practicing medicine for over 50 years. As he studied and learned a wide variety of alternative concepts, his practice gravitated into primarily helping to diagnose and treat those patients who have not been helped by conventional medicine. He's worked with thousands of patients with complex medical illnesses such as fibromyalgia, chronic fatigue, mold toxicity, chronic Lyme disease, autism, and chronic pain.    Related Podcasts: Episode 105: How Anxiety, Depression & Trauma Reactions May Be From Mold and Heavy Metals Episode 106: How Mast Cell Activation, Histamines & Mold Toxicity Place You in a High-Risk Trauma Category   Guides, Tools & Resources: The Essential Sequence - free guide that shows you the difference between stress and trauma states of our nervous system. In just 3 steps, it walks you through what your body needs when it has stored trauma or is in a freeze response. Foundational Journey - a guided 6 week journey into your inner world with a structured sequence of somatic and parts interventions with live online classes. One of the things that happens in just the first 21 days of the Foundational Journey is that people experience a 26% decrease in daily physical pain, speaking to what Dr Schubiner was just talking about, these neural secret pains, can turn off and on, and it's not actually necessarily due to the the injury the body itself. It is a neural circuit and we're managing the pain just by working with the nervous system, looking at the habitual component of it and continuing with essential parts work.   Connect with Dr. Neil Nathan: Website   Disclaimer: By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others. Consult your own physician for any medical issues that you may be having. This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Trauma Healing Accelerated, any guests or contributors to The Biology of Trauma® podcast, or any employees, associates, or affiliates of Trauma Healing Accelerated be responsible for damages arising from the use of the podcast. Comment Etiquette: I would love to hear your thoughts on this episode! Please share your constructive feedback by using personal name or initials so that we can keep this space spam-free, and let's keep the discussion positive!  

If your body is super reactive… even the tiniest change can set off awful symptoms – then you should consider the spectrum of mast cell activation diseases.What most people find enjoyable, like healthy foods, exercise, or even sunlight, can make some feel horrible. Often these symptoms are beyond just “histamine intolerance symptoms.”And while others around you might think you're just “being dramatic” or “making a mountain out of a molehill,” it's clear to you that your body is extremely more reactive than others.It can be hard to get a clear diagnosis and help if you are struggling with mast cell activation diseases – including those with hypermobility syndrome issues like Ehlers-Danlos.If your life feels like you're constantly navigating a minefield of unexpected symptoms to the smallest things, I'm joined by Michelle Shapiro, RD, to talk about what causes you to have a “highly sensitive body.”Michelle Shapiro, RD is an Integrative/Functional Registered Dietitian in NYC who has helped over 1000+ clients reverse their anxiety, heal long-standing gut and immune issues, and approach their weight in a loving way. Michelle has a virtual private practice of 5 nutritionists where she and her team work one-on-one towards these goals. She is the host of the Quiet the Diet Podcast, where she helps listeners bridge the gap between body positivity and functional nutrition.If you've been searching for answers about your own body's unpredictable reactions or want to better understand these complex conditions, let's dive in!In This Episode:What's a “highly sensitive body” problem (that you'll be stuck with forever)?The role of mast cells as “guards” of your immune systemHistamine intolerance symptoms (and why a histamine intolerance diet doesn't help long-term)Histamine intolerance versus Mast Cell Activation DiseasesThe surprising link between MCAS, POTS, and hypermobility syndromeWhy POTS isn't a heart problemThe long COVID–histamine intolerance connectionPractical tips for managing symptoms histamine intolerance symptomsQuotes“Highly sensitive bodies often react in ways we don't expect—things that are supposed to be good for you, like healthy foods or exercise, can make you feel worse.”“Histamine issues don't just cause rashes or itchy skin; they can trigger severe insomnia, anxiety, and even psychosis.”LinksFind Michelle online | InstagramMichelle's podcast, Quiet the DietMichelle's Highly Sensitive Body Hub WaitlistHealthy Skin Show ep. 319: Mast Cell Activation Syndrome: What is MCAS + Why It's So DevastatingHealthy Skin Show ep. 166: Mold + Histamine ConnectionReady to figure out your skin's root causes so you can finally fix your skin + break free from meds to manage your skin?My virtual clinic works with adults worldwide struggling with eczema, psoriasis, rosacea, urticaria, hives, dandruff, perioral dermatitis + more.Trusted by over 1000 clients, we get results WITHOUT restrictive elimination diets.Schedule an assessment call at https://skinrepaircall.com/

Have you ever wondered why you are so reactive - to people, foods, smells, sounds and stress - while other people around you seem completely fine? Y ou are going in overdrive or even going into overwhelm, and think you just must be having a bad day or looking for what triggered you.  The answer might surprise you. A specific cell of your immune system, mast cells, could be actually causing trauma responses in your body, putting you into emotional states, that have less to do with the people around you and more with a compound those cells release, histamine.   Today we're tackling a commonly overlooked underlying reason for anxiety. We will be answering the question, How do mast cell activation and mold toxicity keep us stuck in our responses and triggers to trauma? Before we dive in, I want to dedicate this episode to the loving memory of our guest Beth O'Hara, who passed away in July 2024.  Beth was a pioneering functional naturopath who transformed countless lives through her work with Mast Cell 360, helping people understand and heal from complex cases of Mast Cell Activation Syndrome (MCAS), mold toxicity, and related conditions. She was a friend to me and I am sad to not have more time and conversations with her. In this episode, you'll discover: How to recognize if histamine is driving your anxiety  Why mold exposure can keep your body stuck in trauma responses long after exposure How mast cells bridge your immune system and emotional overwhelm Why and how mast cells will block your ability to create inner safety  Practical tools to decrease reactivity and build resilience For more information and show notes, please visit our website: https://biologyoftrauma.com/biology-of-trauma-podcast/

Are you or someone you love struggling with mysterious, multi-system symptoms—ranging from skin rashes and digestive issues to migraines and unexplained fatigue? You might have been searching for answers but keep hitting dead ends. If you've ever wondered if these diverse and seemingly unrelated symptoms could be connected, it might be time to consider Mast Cell Activation Syndrome (MCAS). MCAS is a condition that affects up to 20% of the population, yet it remains underdiagnosed and misunderstood. In today's episode, I'll be walking you through the ins and outs of MCAS, from how it's diagnosed to the practical steps you can take for treatment. If you're feeling frustrated by traditional medicine's inability to connect the dots on your health issues, this episode will provide some much-needed clarity. Let's explore how MCAS could be the missing link in your health journey and what you can do about it. Key Points: What is MCAS and Why It's Misunderstood MCAS is a multi-system inflammatory condition affecting various parts of the body, causing symptoms like skin rashes, digestive issues, and fatigue. Often misunderstood, MCAS can go undiagnosed for years as patients seek answers from multiple specialists. Dr. Dempsey's Journey to MCAS Expertise Dr. Tanya Dempsey shares her personal journey into recognizing MCAS in her patients, explaining how her curiosity and persistence led her to uncover MCAS as a common, yet often overlooked condition affecting many of her patients. How MCAS is Diagnosed: Laboratory Markers and Clinical Features Diagnosing MCAS requires looking at specific clinical features and laboratory markers. Blood and urine tests can reveal mast cell mediators, while biopsies from gastrointestinal scoping procedures can show elevated mast cells in tissue samples. This segment discusses the complexities and difficulties in obtaining a definitive diagnosis. The Role of Triggers in MCAS Identifying triggers is crucial in managing MCAS. Dr. Dempsey explains how some triggers can be environmental, while others may be internal, making them difficult to pinpoint. Understanding your specific triggers is key to effective treatment. Treatment Options for MCAS: Antihistamines and Beyond The first line of treatment often includes antihistamines—both H1 and H2 blockers. This segment covers how trial and error is often needed to find the right combination for each individual. Natural options like Vitamin C and quercetin are also explored, offering listeners alternatives to pharmaceutical interventions. Living with MCAS: Individualized Treatment Approaches One size does not fit all when it comes to managing MCAS. Dr. Dempsey highlights the importance of a personalized approach, where patients must try different treatments systematically to find what works for them. The need for patience and persistence in the journey to wellness is emphasized. Mast Cell Activation Syndrome might be the missing piece in your complex health puzzle. Whether you're dealing with unexplained chronic symptoms or feeling frustrated by a lack of answers, understanding MCAS could bring you closer to relief. The key takeaway from today's episode is that while diagnosing and treating MCAS can be challenging, it is possible—and it starts with understanding your body's unique triggers. With a combination of personalized treatments, patience, and persistence, you can regain control of your health. If any of this sounds familiar, I encourage you to explore MCAS further and, if necessary, find a practitioner knowledgeable in its diagnosis and treatment. Let's continue this journey toward better health—one piece of the puzzle at a time. How to Connect Dr. Tania Dempsey Dr. Tania Dempsey is a world renowned expert in chronic disease, autoimmune disorders, and mast cell activation syndrome, and is sought after internationally for her knowledge of chronic immune dysregulation. As founder of the AIM Center of Personalized Medicine, Dr. Dempsey uses functional and integrative medicine to get to the patient's root cause(s) of illness, understand why people get sick, help patients understand their body, and understand why it fails them when it does. She works with patients all over the United States, as well as from places around the world such as Israel, England, Thailand, and France. AIM Center for Personalized Medicine: https://drtaniadempsey.com/ How to Connect with Dr. Meg: Women's Wellness Collective: www.megmill.com/collective. use code HEALTH to get your first month 1/2 off Apply to work 1:1 with Dr. Meg: HERE Free Guide: Unraveling the Mystery: Understanding Mast Cell Activation Syndrome for simple steps and protocols you can start today to improve your gut health. You can also follow along on Instagram @drmegmill for daily health tips! Website: www.megmill.com  This content is for educational purposes only and should not be taken as medical advice. Always consult with a healthcare professional before starting any new diet or exercise program.

While high histamine levels are a very real health issue, histamines themself are not the root cause of your symptoms...     While high histamine levels may be responsible for skin rashes, digestive problems, itchiness, headaches, fatigue, brain fog, and more, true relief requires addressing the underlying imbalances causing the elevated histamines in the first place.     So join me on today's Cabral Concept 3238 as we uncover the root cause of histamine imbalances and explore actionable steps you can take to restore balance. Enjoy the episode, and I'd love to hear your feedback!   - - - For Everything Mentioned In Today's Show: StephenCabral.com/3238 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Dr. Fiona Lovely is a longevity, health and wellness expert with specialties in menopause medicine, functional neurology and functional medicine.  She is speaking to the topics of women's health around perimenopause and menopause.   Today, Dr. Lovely welcomes Dr. Meg Mill back to the show to discuss a very contemporary health concern - mast cell activation and the role of histamine and histamine intolerance.  Whether you are a headache sufferer, have experience long haul symptoms from covid infection or shots, have questionable gut health or have mysterious symptoms that no one seems to help with, you will want to listen in.   If you are the person who feels like you have a reaction to EVERYTHING (including water), this episode is for you! Want Dr Meg's histamine guide - she references it in the show?  Please visit histamine guide here.  You can find out more about Dr Meg Mill at her website and on IG @drmegmill Thank you to our sponsors for this episode:

In this episode of Dogs Are Individuals, I explore the world of mast cell tumors, responding to a listener's request for a more detailed understanding of this common canine condition. Drawing on my 20 years of experience as a clinical canine herbalist, I explain what mast cell tumors are, their behavior, and the crucial role mast cells play in your dog's immune system. I also discuss traditional treatment options, including surgery and chemotherapy, while sharing insights into natural approaches to support your dog's health. Tune in for valuable information that could make a difference for your furry friend! Mast Cell Tumor Pt 1 Sponsored By: Green Juju Check Out Rita: SIGN UP FOR MY NEW BOOK Rita's Instagram Facebook Group My Courses My Website and Store Produced By: Drake Peterson

In this episode of the Accrescent podcast, host Leigh Ann welcomes Dr. Steph Peacock to discuss mold toxicity, its impact on health, and effective ways to heal from it. Dr. Peacock shares her journey from being a competitive swimmer to her focus on holistic medicine, particularly mold toxicity and mast cell activation syndrome. They delve into the connection between concussions and mold susceptibility, the significance of nervous system regulation, and the importance of addressing one's environment. Dr. Peacock highlights the need for proper testing and treatment, including environmental assessment, mycotoxin panels, binders, and gut motility support. The conversation also covers additional detoxification methods and the role of emotional and physical stressors on overall health.Product Discount Codes + LinksFall SkincareHerbal Face Food: The Serum IIHerbal Face Food Discount Code: LAL20Facial Lounge: Facial in a Bottle NightFacial Lounge Discount Code: LEIGHANNHoneybee Hippie: Honey Hydrate Tallow BalmHoneyBee Hippie Discount Code: LEIGHANN10Micro Balance HealthMicro Balance Health: WebsiteMicro Balance Health Code: ACCRESCENTBuoy ElectrolytesBuoy: Website (link gives 20% discount)Work w/Leigh AnnLearn: What is EVOX Therapy?Book: Schedule a Session or FREE Discovery CallMembership: What is The Uplevel Lab?Interview LinksBook Club: Now FREE, Join the Group Today!Book Club: Link if You Are NOT A Member of the Uplevel LabBook Club: Link if You ARE a Member of the Uplevel LabProduct: Ermi Dust TestProduct: Immunolytics TestLearning: Nervous System: Accrescent Podcast Episodes on the Nervous System: 147, 140, 115, 105, 104Product: Activated Charcoal: My Favorite Activated Charcoal (discount code: LEIGHANNLINDSEY)Product: Infrared Sauna:

https://renegadehealthboss.comIn episode 127 Heather Gray FDN-P interviews leading expert Beth O'Hara to explore the complexities of Mast Cell Activation Syndrome (MCAS), a condition affecting many with chronic health issues. They break down why MCAS is often overlooked, its connection to chronic conditions like mold toxicity and Lyme disease, and practical ways to manage it. They also introduce a holistic method for tackling these issues, developed after working with over 1,000 patients. Beth is no longer with us and her work and legacy continues to inspire people and change their lives.  Listen now to find out more for yourself.  We love you Beth and you are missed. In this podcast you will discover 00:00 Heather introduces the show and the critical discussion on MCAS and its growing prevalence. 02:36 A functional naturopath joins the conversation to explain MCAS and why it's often missed. 06:09 Beth O'Hara  shares their personal battle with chronic health issues, including mold toxicity and MCAS, detailing the struggles and root causes. 08:20 A detailed breakdown of the role of mast cells, their presence in almost every tissue of the body and their influence on overall health. 15:05 Common triggers for MCAS, including mold toxicity, tick-borne infections, and chronic stress. 16:36 Beth O'Hara explains calming mast cells through diet changes, supplements like quercetin, and nervous system regulation to reduce flare-ups. 21:05 Discussion on how environmental factors like mold and air quality contribute to chronic illness, especially when not properly detected by mold inspectors. 25:33 Introduction of a free symptom survey to help individuals determine if they might be dealing with MCAS, based on the number of symptoms they have. 32:12 Heather and Beth O'Hara  explain why addressing mold toxicity is critical before dealing with chronic infections and how doing so can re-regulate the immune system. 37:10 Salicylate intolerance can complicate treatment, especially when herbal remedies aren't working, and ways to adjust for it. 41:00 Heather and Beth O'Hara explores structural causes of vagal nerve dysfunction, such as neck instability or diaphragm issues. 45:02 Beth O'Hara  shares how her name became synonymous with mass cell knowledge within the health community. 48:34 The nervous system's role in chronic conditions, focusing on the limbic system, vagus nerve, and structural issues  50:20 The regulating vagus nerve signaling to address mast cell activation and its effects on inflammation. To Get BioMed: Contact Dr. Drobot here https://thebiomedcenter.com/ Tel:480-614-5820    Only contact the Scottsdale location To get CAROL Bike Click here https://carolbike.com/  use code RHB to get $100 off The CAROL Bike offers a 100-day return policy.  full refund, buy with confidence.  If you are a practitioner please open an account with MHP here www.mhpvitamins.com  Guest Bio: Beth O'Hara, a Functional Naturopathic Consultant, specializes in complex conditions like Mast Cell Activation Syndrome, Histamine Intolerance, and Mold Toxicity. As the founder and clinical director of Mast Cell 360, she created a practice focusing on holistic healing, addressing biochemical, environmental, and emotional factors. Having suffered from these conditions herself, she developed the MC360™ method, which has helped thousands regain their health. Find out more about Mast Cell 360 mastcell360.com If you or someone you know is struggling with suicidal thoughts please contact the suicide hotline https://988lifeline.org/  Just get help, you are not weak because you ask for help. You are brave!!  You are worth getting help.  Don't give up Download your free video series Real Cooking For Real Life here.https://renegadehealthboss.com/real-cooking-for-real-life-recipe-book/ --- Support this podcast: https://podcasters.spotify.com/pod/show/renegadehealthboss/support

Welcome back, Dr Rachel Venable, DVM, MS, DACVIM (oncology) to the podcast! This week we discuss mast cell tumors!I don't know about you... but I always get confused about current guidelines with MCT. They can be anything from low-grade removal and no sweat... to multiple high-grade panic! How much margin do you really need? When is Stelfonta an option? Check out all this great conversation all about MCTs and how to approach them from a boarded oncologist!TIMESTAMPSIntro 00:00Predispositions To Mast Cell Tumors 01:08Single Mast Cell Tumors 02:25Multiple Mast Cell Tumors 08:30Are Subcutaneous Mast Cell Tumors More Of A Concern? 13:54Staging Mast Cell Tumors 15:18An Overview Of Stelfonta 17:36Outro 20:10

Immune discusses two stories of immune cells eating other cells: microglia engulfing brain neurons to shape cortical development and behavior, and mast cells trapping neutrophils to increase their functional and metabolic fitness. Hosts: Vincent Racaniello, Cindy Leifer, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Microglia shape cortical development and behavior (Cell) Neutrophil trapping by mast cells (Cell) Time stamps by Jolene. Thanks! Music by Steve Neal. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv

Closing chapters, Diabetes, Cholesterol, Mast Cell, & Vitamin D! Your body heals itself and Janet knows how to engage all corners of that super power! Achieve full immunity and follow JANET ON IG // FOLLOW @deplorablejanet ON IG&VISIT PARANOIRADIO.COM ☂️ --- Support this podcast: https://podcasters.spotify.com/pod/show/paranoiradiopodcast/support

I discuss my confusing bloodwork results from my last appointment with Shoemaker Protocol Dr. Peg; why I'm back to exploring MAST Cell or MCAS issues; the unusual reason the Interstitial Cystitis with which I was diagnosed in 2003 has returned; and my latest in the MARCoNS soap opera! ‼️ I am not a doctor or health professional. If you hear something you would like to attempt in this episode, please consult with your physician or mental health professional first. 

In today's episode, I'm discussing Mast Cell Tumors following a recent conversation with a client whose dog has been diagnosed with one, as well as a listener's question on the topic. I'll explore what Mast Cell Tumors are, why they develop, and the role of allergies and histamines in their growth. I'll cover the symptoms to watch for, discuss the generally positive prognosis, and outline the various treatment approaches and tumor grades. Plus, we'll talk about which herbs are great for prevention and treatment. Tune in for a comprehensive guide to understanding and managing Mast Cell Tumors in dogs! Sponsored By: Goodness Gracious Real Mushrooms Show Links: MYCODog Feral Fungi Check Out Rita: SIGN UP FOR MY NEW BOOK Rita's Instagram Facebook Group My Courses My Website and Store Produced By: Drake Peterson

In this episode, we discuss how you can proactively screen and work on prevention of diseases. Show Notes: 0:00 – A tribute to Beth O'hara of Mast Cell 360 4:00 Reactive and invasive screening for cancer versus proactive and preventative screening 4:50 the POINT Approach – an understanding of bioindividuality 7:15 – identifying stressors and getting out of “fight or flight” mode 9:25 – look to replace personal care products that have toxic ingredients 12:00 – Emotional stressors and evaluating what can be changed 13:00 – bedtime tips and the importance of consistent wake times 14:15 – symptoms are never normal, but symptoms are telling us something needs rebalancing 15:20 – Supplements are the last step because all other areas need to be addressed first 15:40 – multiple breast biopsies and horrid experiences 19:00 –Prolactinoma, a benign pituitary tumor 20:00 – a Holistic approach, ultrasound and thermography and targeted therapies 23:40 – practicing what I preach and testing instead of guessing 25:52 – Season 3 with Dr. Diana Driscoll, founder of POTS Care next week Functionally Enlightened Follow us on IG ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@functionallyenlightened⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to be notified when new interviews with amazing functional practitioners and chronic illness warriors are published. Visit us at ⁠⁠www.functionallyenlightened.com⁠⁠ to find out how we work or to contribute to the ongoing research on implant illness.

In this episode, Dr. Linda Bluestein, the Hypermobility MD, delves into the intricate connections between the immune system and hypermobility disorders with Dr. Kara Wada. A quadruple board-certified physician and Sjogren's patient, Dr. Wada shares her expertise on mast cell activation syndrome, autoimmunity, and the role of inflammation. Discover holistic approaches to managing these conditions and gain valuable insights into the latest research and treatments. Don't miss the special hypermobility hacks at the end! Takeaways: Interplay Between Immune System and EDS: The immune system plays a significant role in hypermobility disorders, with conditions like mast cell activation syndrome and autoimmunity frequently seen in patients with EDS. Differences in Allergy and Mast Cell Activation: Allergy involves the immune system's memory of proteins, whereas mast cell activation syndrome can be triggered by various factors, often without the presence of traditional allergies. Inflammation's Role in Chronic Conditions: Chronic inflammation is a core issue in many modern diseases, including EDS and autoimmune disorders. It's the body's prolonged response to injury or infection that can lead to various health issues. Impact of Hormones: Hormones, particularly estrogen and progesterone, significantly influence immune system functioning and can affect conditions like POTS, often seen in EDS patients. Holistic and Lifestyle Approaches: Managing EDS and related conditions can benefit from holistic approaches, including anti-inflammatory diets, regular movement, adequate sleep, and stress management techniques such as meditation and journaling. Connect with YOUR Bendy Specialist, Dr. Linda Bluestein, MD at https://www.hypermobilitymd.com/.   This episode is sponsored by EDS Guardians. If you want to learn more, check them out here: https://www.edsguardians.org/    Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them.

In this episode, Dr. Linda Bluestein, the Hypermobility MD, delves into the intricate connections between the immune system and hypermobility disorders with Dr. Kara Wada. A quadruple board-certified physician and Sjogren's patient, Dr. Wada shares her expertise on mast cell activation syndrome, autoimmunity, and the role of inflammation. Discover holistic approaches to managing these conditions and gain valuable insights into the latest research and treatments. Don't miss the special hypermobility hacks at the end! Takeaways: Interplay Between Immune System and EDS: The immune system plays a significant role in hypermobility disorders, with conditions like mast cell activation syndrome and autoimmunity frequently seen in patients with EDS. Differences in Allergy and Mast Cell Activation: Allergy involves the immune system's memory of proteins, whereas mast cell activation syndrome can be triggered by various factors, often without the presence of traditional allergies. Inflammation's Role in Chronic Conditions: Chronic inflammation is a core issue in many modern diseases, including EDS and autoimmune disorders. It's the body's prolonged response to injury or infection that can lead to various health issues. Impact of Hormones: Hormones, particularly estrogen and progesterone, significantly influence immune system functioning and can affect conditions like POTS, often seen in EDS patients. Holistic and Lifestyle Approaches: Managing EDS and related conditions can benefit from holistic approaches, including anti-inflammatory diets, regular movement, adequate sleep, and stress management techniques such as meditation and journaling. Connect with YOUR Bendy Specialist, Dr. Linda Bluestein, MD at https://www.hypermobilitymd.com/.   This episode is sponsored by EDS Guardians. If you want to learn more, check them out here: https://www.edsguardians.org/    Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them.

Anaphylaxis, organ failure & common allergies and more! Janet supplies hope and dumps a massive load of information on how to negate this mortal disease and refill your organs, body and mind with the knowledge to combat current Mast Cell Activations. // FOLLOW @DeplorableJanet on Instagram & VISIT US AT PARANOIRADIO.COM ☂️ --- Support this podcast: https://podcasters.spotify.com/pod/show/paranoiradiopodcast/support

Text Dr. Lenz any feedback or questions Understanding Ehlers-Danlos Syndrome: Insights from Jeannie Di BonIn this episode, a special guest, Jeannie Di Bon, a movement therapist who specializes in hypermobility, Ehlers-Danlos Syndrome (EDS), and chronic pain, shares her expertise and personal journey. Diagnosed with EDS, Mast Cell Activation Syndrome, POTS, and chronic fatigue syndrome, Jeannie discusses the challenges of diagnosing these conditions, the significance of diagnosis for patients, and her development of a supportive online community and tools via the Zebra Club. She also addresses the complexities of EDS, similar conditions, and the importance of clinician awareness.00:00 Welcome to the Podcast: Introducing Jeannie Di Bon01:15 Understanding Ehlers Danlos and Hypermobility03:26 The Challenge of Diagnosis and Misdiagnosis09:59 Jeannie's Personal Journey with EDS14:13 From Chronic Pain to Movement Therapy: Jeannie's Professional Evolution22:14 Expanding Access: The Zebra Club and Online Resources24:58 Addressing Comorbidities: ADHD, Autism, and Hypermobility26:51 Final Thoughts: Hope, Support, and EducationSupport the Show.A Fibromyalgia Starter Pack, which is a great companion to the book Conquering Your Fibromyalgia, is now available. Dr. Michael Lenz practices general pediatrics and internal medicine primary care, seeing patients from infants through adults. In addition, he also will see patients with fibromyalgia and related problems and patients interested in lifestyle medicine and clinical lipidology. To learn more, go to ConquringYourFibromyalgia.com. Remember that while Dr. Lenz is a medical doctor, he is not your doctor. All of your signs and symptoms should be discussed with your own physician. He aims to weave the best of conventional medicine with lifestyle medicine to help people with chronic health conditions live their best lives possible. Dr. Lenz hopes that the podcast, book, blog, and website serve as a trusted resource and starting point on your journey of learning to live better with fibromyalgia and related illnesses.

Dr Theoharis Theoharides, aka “The Mast Cell Master”, has been exploring the world of Mast Cells, their influence on our bodily functions, neurology and genetic make up, for over half a century.  The Director of the Center of Excellence for Neuroinflammation Research and Professor at the Institute for Neuro-Immune Medicine at Nova Southeastern University joins us this week to discuss the role that Mast Cells play in neurological conditions such as Long Covid, and the way in which we influence and change our mast cells' behaviour with our infections, stress levels, trauma and activity.Living with Long Covid? How was your week?Website - https://www.tlcsessions.net/Twitter - @SessionsTlc https://twitter.com/sessionstlcInsta - @tlcsessions https://www.instagram.com/tlcsessions

Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions:    Lindsey: hi dr. cabral - i have had what seems to be kidney pain for years. i only get relief when my spouse does really deep tissue massages on my lower back. after, my stomach makes gurgling noises and it ends up being gas. ive gone 1 time to a gastro for this and they said it's not my kidneys but inflamed intestines appearing as kidney pain. can you please point me in the right way ?   Katherine: Hi Dr. Cabral, Thank you for all u do! You are my "benchmark" in the health world. Wondering what you would recommend a member of your family if this happened to them. Summer 2022 I had a really bad kidney stone that landed me in the hospital. I passed it. Since then I had about 4 more instances of kidney stones (but not as severe-was able to take some meds to ease the pain until it passed). Recently I went for a CT Scan and it showed my left Ureter dilated. The Urologist suggested another CT scan with dye or a to putna camera in and see if something is there causing a blockage or a tumor. Curious what I can do to be more proactive.   Tina: Love your show :) what is the best alternative to a mammogram? Thermal imaging anything you can recommend please I do not want to go for a mammogram. I've read other women with mast cell activation having breast cancer. Also, really trying hard to get rid of mast cell activation. Is cancer is a sign of mast cell activation ? Alma powder will it help mast cell activation? Alma powder better then berberine? Been researching alternatives to semaglutitde with myself having insulin resistance type 1 diabetes I am full plant based no fat no sugar no salt Please need help   Olivea: Dr. Cabral, The information you provide is wonderful. I just listened to your podcast 'why not fast until lunch' I have never been a huge proponent of fasting for myself simply because of my schedule. Curious what you would recommend for my schedule in regards to fasting and overall health - I try to eat dinner around 6:30/7pm each night. I wake up at 4:45 for the gym - I typically eat an apple on my way to the gym (I go to CrossFit) - my workout is an hour (starting at 5:15am) and then I have 1 egg + some egg whites around 7am, I then make myself a smoothie with water, fruit, and almond milk and take it to work with me and it usually takes me a few hours to drink it. I guess more of what I am asking is - someone who has morning workouts - what do you recommend for fasting?   Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!      - - - Show Notes and Resources: StephenCabral.com/3039 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

In this episode, we sit down with Dr. Grace Liu, the founder of The Gut Institute, to delve into the intricacies of gut health and its paramount importance. She brings her extensive expertise to the table, sharing vital insights on why addressing gut health should be a top priority for overall well-being. Dr. Grace also shares top peptides to use, how to fix leaky gut, the role of different probiotics like Akkermansia, histamine intolerance, and more. Tune in to learn how you can optimize your gut health!Dr. Grace Liu PharmD is an IFM-trained functional medicine practitioner and founder of The Gut Institute. She is a clinical pharmacist with a doctorate in practice for 20+ years and specializes in complex disease management. Dr. Liu consults and helps clients gain optimal performance through rebuilding the microbiome after damage from modern living. She uses nutrigenomic tools and other advanced functional lab testing to give the solutions, strategies and treatments that reverse modern gut dysbiosis and disease. SHOW NOTES:0:51 Welcome to the show!3:55 Dr. Grace Liu's Bio4:27 Welcome her to the podcast!5:43 Why are we still overlooking gut health?7:25 About BPC-157 Peptide8:41 Optimizing the basics first10:45 Vitamin D-Gut Connection11:39 Fixing gut permeability14:58 Addressing parasite exposure16:14 Leaky Gut Procol19:34 Gut testing options23:32 Long COVID Protocols26:32 Do you have a parasite?31:18 AMPs (Peptides) & Probiotics34:53 Benefits of Akkermansia37:19 Mast Cell & Histamines40:47 Adrenal Protocols & markers of stress42:21 Benefits of warmer body temperatures46:23 Binders for supporting detox49:02 Blue Zone diets & dietary starches51:03 Oxalates, yeast & molds55:40 Stimulating oxytocin & vagal tone59:00 Getting drunk off bread1:01:16 Balancing the immune system & histamine overload1:10:42 Where to find her1:12:34 Her final piece of advice1:14:08 Thanks for tuning in!RESOURCES:The Gut Institute - Discount code: BABES10Instagram: Gut_GoddessFacebook: The Gut InstituteYouTube: Dr. Grace LiuPinterest: The Gut InstituteTikTok: Dr. Grace LiuBiOptimizers Magnesium Breakthrough - code: BIOHACKERBABES10 + subscribe to receive free gifts and additional discountsOur Sponsors:* Go to Puori.com/BIOHACKERBABES and use our promo code BIOHACKERBABES for 20% off site wide!Support this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands

SummaryDr. Tania Dempsey discusses mast cell activation syndrome (MCAS) with a focus on environmental triggers of mast cell disease.  TakeawaysInfections can trigger mast cell reactions and people with MCAS may react differently than those without.Identifying and addressing environmental triggers, such as mold and plastics, is important in managing MCAS. Immunotherapy for allergies and asthma may impact MCAS symptoms. Treatment options like Xolair (Omalizumab), ketotifen, cromolyn, and low dose naltrexone (LDN) are discussed.  Nutrition, particularly protein intake, supports overall health and affects MCAS symptoms.Fish can be a good source of protein, but it is important to be aware of mercury levels and choose smaller fish.Testing mercury levels can help identify potential toxicity and guide treatment.Antihistamines can be beneficial for managing MCAS symptoms and should not be feared.Individuals with MCAS may have sensitivities to scents, environmental triggers, and EMFs.Finding healthcare providers who understand and can effectively treat MCAS is crucial.Chapters ➡00:00 Introduction to MCAS and Dr. Tanya Dempsey02:28 Infections and MCAS14:31 Immune Deficiency and Infections28:37 Environmental Triggers37:00 Air Purification and Food Quality42:01 Quality of Meat vs. Pesticide-Free Vegetables43:11 Fish as an Alternative to Meat44:32 Toxins in Fish and Mercury Levels46:02 Detoxing Mercury and Sushi Concerns47:08 Reactions to Sushi and Scombroid Food Poisoning48:43 Sensitivity to Scents and Environmental Triggers49:30 Long-Term Antihistamine Use and Dementia52:21 Reactions to Laundry and Facial Products56:23 Treatment Options after Failing Xolair57:12 Food Dyes and MCAS58:18 EMFs and MCAS59:22 Why Some Doctors Fail to Believe in MCAS01:03:41 Immunotherapy for Allergies and MCAS01:04:56 Managing Heat, Sun, and Exercise Triggers01:09:54 Diagnosing MCAS and Lab Testing Challenges01:11:20 Final Thoughts and Finding AnswersConnect with YOUR Bendy Specialist, Dr. Linda Bluestein, MD at https://www.hypermobilitymd.com/.   Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them.

SummaryDr. Tania Dempsey discusses mast cell activation syndrome (MCAS) with a focus on environmental triggers of mast cell disease.  TakeawaysInfections can trigger mast cell reactions and people with MCAS may react differently than those without.Identifying and addressing environmental triggers, such as mold and plastics, is important in managing MCAS. Immunotherapy for allergies and asthma may impact MCAS symptoms. Treatment options like Xolair (Omalizumab), ketotifen, cromolyn, and low dose naltrexone (LDN) are discussed.  Nutrition, particularly protein intake, supports overall health and affects MCAS symptoms.Fish can be a good source of protein, but it is important to be aware of mercury levels and choose smaller fish.Testing mercury levels can help identify potential toxicity and guide treatment.Antihistamines can be beneficial for managing MCAS symptoms and should not be feared.Individuals with MCAS may have sensitivities to scents, environmental triggers, and EMFs.Finding healthcare providers who understand and can effectively treat MCAS is crucial.Chapters ➡00:00 Introduction to MCAS and Dr. Tanya Dempsey02:28 Infections and MCAS14:31 Immune Deficiency and Infections28:37 Environmental Triggers37:00 Air Purification and Food Quality42:01 Quality of Meat vs. Pesticide-Free Vegetables43:11 Fish as an Alternative to Meat44:32 Toxins in Fish and Mercury Levels46:02 Detoxing Mercury and Sushi Concerns47:08 Reactions to Sushi and Scombroid Food Poisoning48:43 Sensitivity to Scents and Environmental Triggers49:30 Long-Term Antihistamine Use and Dementia52:21 Reactions to Laundry and Facial Products56:23 Treatment Options after Failing Xolair57:12 Food Dyes and MCAS58:18 EMFs and MCAS59:22 Why Some Doctors Fail to Believe in MCAS01:03:41 Immunotherapy for Allergies and MCAS01:04:56 Managing Heat, Sun, and Exercise Triggers01:09:54 Diagnosing MCAS and Lab Testing Challenges01:11:20 Final Thoughts and Finding AnswersConnect with YOUR Bendy Specialist, Dr. Linda Bluestein, MD at https://www.hypermobilitymd.com/.   Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them.

Why talk to a hematologist about mast cell disease and systemic mastocytosis treatment? Dr. Douglas Tremblay, a leading hematologist, joins Dr. G and Kortney to discuss the role of a hematologist-oncologist in diagnosing and treating mastocytosis. We discuss bone marrow's vital role in diagnosing and treating systemic mastocytosis.  Dr. Tremblay discusses the latest KIT inhibitors, a promising group of medications, and explains the difference between indolent and advanced systemic mastocytosis. He clarifies how KIT inhibitors work and emphasizes the importance of managing side effects. Finally, Dr. Tremblay provides insights into the future of KIT inhibitor approval and explores the possibility of participating in a clinical trial for Bezulastinib.  What we cover in this episode about treating systemic mastocytosis: What is a hematologist looking at with mast cell disease patients? Mast cell diseases and the role of bone marrow Bone marrow biopsy for systemic mastocytosis  What is a bone marrow biopsy? Information bone marrow biopsy provides for diagnosis KIT mutation  KIT mutation testing in bone marrow and blood (digital droplet PCR) Indolent Mastocytosis versus Advanced Mastocytosis Current research for treating mast cell disease How KIT inhibitors work Do KIT inhibitors weaken the immune system? KIT Inhibitors discussed in this episode: Avapritinib Bezulastinib Elenestinib Are KIT inhibitors a cure for mast cell disease? Determining the tolerance for side effects of medications when researching and adding new medicines for diseases  The meaning of ‘NIB' in the medication names The timeline for the new KIT inhibitors approval The type of patient that can participate in the clinical trials for Bezulastinib Resources about mast cell disease: Dr. Tremblay: https://profiles.mountsinai.org/douglas-a-tremblay Dr. Tremblay's email: douglas.tremblay@mssm.edu  Mast Cell Disease Overview: https://allergyasthmanetwork.org/health-a-z/mast-cell-diseases/ What is Anaphylaxis? https://allergyasthmanetwork.org/anaphylaxis/ What is Epinephrine? https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/ The Mast Cell Disease Society: https://tmsforacure.org/ Current studies enrolling patients: https://tmsforacure.org/clinical-trials/

I give you the gory details of my first colonic

Make sure to support this podcast by heading over to Paleovalley.com/NwJ and the 15% off discount will automatically be applied to your first order. _____I'm excited to sit down with Beth O'Hara. We talk about histamines and MCAS, effects of mold in the home environment, and much more. Make sure to listen to the full interview to learn more.Beth O'Hara is a Functional Naturopathic Consultant specializing in complex, chronic cases of Mast Cell Activation Syndrome, histamine intolerance, mold toxicity, and related conditions. She is the founder and clinical director of Mast Cell 360, a functional naturopathy practice designed to address all factors surrounding health conditions – biochemical, physiological, environmental, epigenetic, and emotional wellness.Beth crafted Mast Cell 360 to resemble the practice she wished had existed when she was severely ill with Mast Cell Activation Syndrome, histamine intolerance, mold toxicity, neural inflammation, Lyme, fibromyalgia, and chronic fatigue. Her present mission is to serve as a guiding light for others navigating Mast Cell Activation Syndrome, histamine intolerance, and these related conditions in their healing journeys.We discuss the following:All about Beth O'HaraHistamines and MCASSymptoms of histamine intoleranceTesting for histamine and MCASLong COVID and MCASHow to support the nervous systemThoughts on mast cell stabilizer medicationsSensitivity to DAO supplementsMold's impact on the pancreasEffects of mold in the home environmentSupporting mold illness recoveryHealing from MCASWhere to find Beth O'Hara_____RESOURCESBeth's WebsiteBeth's FacebookHistamine Digest 360 with DAOMast Cell Nervous System Reboot Master ClassNwJ Mind-Body Program____SIGN UP FOR MY WEEKLY NEWSLETTERCHECK OUT MY BOOK, Carnivore CureCHECK OUT MY SECOND BOOK, The Complete Carnivore Diet for Beginners: Your Practical Guide to an All-Meat Lifestyle_____ ADDITIONAL RESOURCESNutrition with Judy ArticlesNutrition with Judy ResourcesNutrition with Judy Podcast_____ FIND ME

In today's episode, we interview Dr. Leonhard Weinstock on the topic of mast cell activation disorders and the gut, which are becoming epidemic in the population. Mast Cell Activation Syndrome (MCAS) is a complex and often misunderstood disorder that involves the abnormal release of mast cells in the body. These cells are an essential part of our immune system, but when they become overactive, they can trigger a range of symptoms and health issues. Key Points ✅ How did you get into the study of medicine and gastroenterology and what led you to become an expert in MCAS? ✅ Describe in detail what symptoms are related to MCAS and how symptoms might manifest in the gut and other areas of the body? ✅ What do you think we've seen a rise in MCAS diagnoses? ✅ Let's talk more about TRIAD (EDS, MCAS, POTS) and how this can manifest together? ✅ What are some ways we can treat MCAS? ✅ What is the connection with MCAS and psychiatric symptoms/mental illness?   Dr. Leonard B. Weinstock Dr. Leonard B. Weinstock is Board Certified in Gastroenterology and Internal Medicine. He is an Associate Professor of Clinical Medicine and Surgery at Washington University School of Medicine. Dr. Weinstock received his medical degree from University of Rochester School of Medicine and completed his postgraduate training and was chief resident in Internal Medicine at Rochester General Hospital. His Gastroenterology Fellowship was performed at Washington University School of Medicine. Dr. Weinstock is an active lecturer and has published more than 140 articles, abstracts, editorials and book chapters. He has given lectures throughout the world.  He is currently researching mast cell activation syndrome, small intestinal bacterial overgrowth, restless legs syndrome, mold toxicity, and rosacea. Fifteen articles related to MCAS have been published within the last 5 years. https://www.gidoctor.net/

Can a low-histamine diet help with mast cell disease? Why is stress a big trigger for mast cell disease? Dr. Milner joins us again to discuss two hot topics in managing mast cell disease. We start by demystifying the low histamine diet and sharing when appropriate. The answer may be different from what you expect or want to hear. We also talk about stress, a topic we are learning impacts so many chronic diseases, especially those related to mast cells. Stress can worsen symptoms, and in this episode, both doctors emphasize the importance of stress management techniques.   What we cover in this episode about low histamine diet and stress management Why go on a low histamine diet? What is histamine intolerance?  How well do low histamine diets work for mast cell disease? The impact of stress on mast cell disease Stresses impact on the gut Stress management is integral in mast cell disease treatment  More resources about mast cell disease: Mast Cell Disease Overview: https://allergyasthmanetwork.org/health-a-z/mast-cell-diseases/ What is Anaphylaxis? https://allergyasthmanetwork.org/anaphylaxis/ What is Epinephrine? https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/ The Mast Cell Disease Society: https://tmsforacure.org/

Where do you begin with mast cell disease treatment when there is such variation among patients?  Dr. Milner is back with us to discuss the difficulties in treating mast cell activation syndrome and mastocytosis. We will discuss the different approaches to treating mast cell disease and the medications used for mastocytosis treatment. Since no single treatment plan works for everyone, we will explore multiple strategies that can be helpful in managing this condition. A note: when you hear MCAS mentioned, it stands for Mast Cell Activation Syndrome. What we cover in our episode about treating mast cell diseases: What are the steps taken to treat mast cell diseases? Histamine blockers: antihistamines for mast cell disease and H2 blockers Mast cell stabilizers: Cromolyn and Ketotifen Xolair  Other medications that have been used but not recommended: aspirin, steroids, Singulair Epinephrine and anaphylaxis Tyrosine kinase inhibitors (TKI) for Mastocytosis: Avapritinib, Midostaurin Safety concerns and side effects of Tyrosine kinase inhibitors  Multidisciplinary approach to managing mast cell disease About our guest - Dr. Josh Milner Joshua Milner, MD, is a renowned leader in discovering and understanding genetic diseases leading to allergic symptoms, including Hereditary Alpha Tryptasemia Syndrome, PLAID, PGM3 deficiency, ERBIN mutation, and others. With a background in biology from MIT and an MD with distinction in immunology from Albert Einstein College of Medicine, Dr. Milner has extensive experience in pediatrics and allergy and immunology, serving as chief of the Laboratory of Allergic Diseases at NIAID. His vision is to leverage genetic variation to improve diagnosis and care for patients with allergic diseases through comprehensive genetic sequencing and functional studies, aiming for personalized medicine and interdisciplinary collaboration in pediatric allergy, immunology, and rheumatology. More about Dr. Milner:  https://www.pediatrics.columbia.edu/profile/joshua-milner-md More resources about mast cell disease: Mast Cell Disease Overview: https://allergyasthmanetwork.org/health-a-z/mast-cell-diseases/ What is Anaphylaxis? https://allergyasthmanetwork.org/anaphylaxis/ What is Epinephrine? https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/ The Mast Cell Disease Society: https://tmsforacure.org/ FDA Approves AYVAKIT® (avapritinib) as the First and Only Treatment for Indolent Systemic Mastocytosis: https://ir.blueprintmedicines.com/news-releases/news-release-details/fda-approves-ayvakitr-avapritinib-first-and-only-treatment

This episode is a little more serious as we talk about what happened to Court last week when she was in and out of anaphylaxis for four days. Mast Cell Activation Syndrome is a diagnosis that was introduced into both of our lives last June, and this tale is just a piece of the ever-growing puzzle surrounding this autoimmune condition. We are not doctors, nor experts on the matter, but we figured we'd share this journey with you just as we did with RV Life - learning and sharing as we go. Here are some links we reference in the episode, and that we found helpful when we were first diagnosed with this condition. ⁠What is MCAS?⁠ ⁠What is anaphylaxis? Signs and stages⁠ ⁠Signs and stages of anaphylaxis ⁠(+biphasic anaphylaxis) ⁠Bruder Mask⁠ (affiliate link) ⁠Reesa Teesa the story that broke the Internet ⁠ ---------

BoneCoach™ Osteoporosis & Osteopenia - Joining us today to explore histamines, mast cell activation syndrome, and osteoporosis is Dr. Meg Mill.=>>FREE Stronger Bones Masterclass (Gain Access Now!)=>>FREE 7-Day Osteoporosis Kickstart=>>Apply to join the Stronger Bones Solution Program w/ the BoneCoach™ Team***Topics Covered0:00 - Episode start1:29 - Who is Dr. Meg Mill4:48 - Her transition from conventional to functional medicine6:00 - Understanding histamine and its role in the body7:51 - Causes of histamine imbalance9:34 - A quick look at genetics and histamine intolerance10:22 - Mast Cell Activation Syndrome (MCAS) explained12:35 - Effects of MCAS on bone health and osteoporosis15:21 - How to diagnose histamine issues or MCAS16:57 - Functional medicine's approach to histamine problems19:17 - Strategies for managing histamine intolerance21:57 - High histamine foods to avoid24:16 - Additional tips for histamine management25:39 - Long-term approach to addressing histamine intolerance and MCAS27:50 - Special summit announcement29:22 - Where to find more help and resources from Dr. Meg Mill***Resources MentionedFind all resources mentioned and show notes @=>> https://bonecoach.com/histamine-mast-cell-osteoporosis-dr-meg-mill ***What can you do to support your bone health and this podcast?1. Hit the “Subscribe” Button. 2. Leave a review. Thank you!

Put on your detective hat because we will be diving into how to diagnose mast cell disease! Dr. G and Kortney are joined by Dr. Josh Milner, one of the top experts in the field of mast cell disease, as they dive into the complexities of diagnosing mast cell disorders, focusing on cases of unexplained anaphylaxis and using this as our guide to understanding all of the tests that doctors do to figure out what is happening with your mast cells.  From histories to blood and urine tests to Darier's sign, bone marrow biopsies and more, we dig into the many tests needed for the detective work diagnosing mast cell disease. We learn that a nuanced approach is required to diagnose mast cell disorders and the importance of thorough evaluation to differentiate between potential causes. This podcast was made in partnership with Allergy & Asthma Network. We thank Blueprint Medicines for sponsoring this podcast. What we cover in our episode about diagnosing mast cell disease: Unexplained anaphylaxis could be linked to mast cell disorders. Diagnostic tools: Blood tryptase test (fast but time-sensitive) Urine metabolite tests (easier, longer window) Skin rash assessment (urticaria pigmentosa) Bone marrow biopsy (serious cases) Symptoms: Sudden episodes, chronic issues like fatigue, depression. About our guest - Dr. Josh Milner Joshua Milner, MD, is a renowned leader in discovering and understanding genetic diseases leading to allergic symptoms, including Hereditary Alpha Tryptasemia Syndrome, PLAID, PGM3 deficiency, ERBIN mutation, and others. With a background in biology from MIT and an MD with distinction in immunology from Albert Einstein College of Medicine, Dr. Milner has extensive experience in pediatrics and allergy and immunology, serving as chief of the Laboratory of Allergic Diseases at NIAID. His vision is to leverage genetic variation to improve diagnosis and care for patients with allergic diseases through comprehensive genetic sequencing and functional studies, aiming for personalized medicine and interdisciplinary collaboration in pediatric allergy, immunology, and rheumatology. More about Dr. Milner:  https://www.pediatrics.columbia.edu/profile/joshua-milner-md More resources about mast cell disease: Mast Cell Disease Overview: https://allergyasthmanetwork.org/health-a-z/mast-cell-diseases/ What is Anaphylaxis? https://allergyasthmanetwork.org/anaphylaxis/ What is Epinephrine? https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/ The Mast Cell Disease Society: https://tmsforacure.org/

Have you ever considered whether your nasal congestion, IBS, brain fog, and hives are related?  This podcast was made in partnership with Allergy & Asthma Network. We thank Blueprint Medicines for sponsoring this podcast. Dr. Anne Maitland joins us as we delve into the complex world of mast cell disease. From the confusing range of symptoms to the unpredictable nature of each person's experience, we unravel the mysteries that make mast cell disorders so uniquely difficult to tackle. Dr. Maitland is an expert in allergy and immunology and sheds light on the diverse manifestations of mast cell dysfunction, from headaches and nasal congestion to gastrointestinal issues and skin reactions like hives.Dr. Maitland emphasizes the importance of recognizing mast cell dysfunction's impact across different organs for accurate diagnosis and management. What we cover in our episode about mast cell disease: Symptoms of mast cell disease How to connect the dots of mast cell disease symptoms What is a sign that your symptoms are related to mast cells The job of mast cells and their scientific history Is an anaphylactic reaction a mast cell disease? What triggers mast cell disease?  Mast cell targetted medications and how this can hide your symptoms About our guest - Dr. Maitland Dr. Maitland is a highly respected physician and a Fellow of the American College of Allergy, Asthma, and Immunology. She was named New York Times' Super Doctors in 2011 and one of America's Top 21 Women's Doctors by Lifescript.com in 2009. Dr. Maitland is actively involved in creating awareness of immune-mediated disorders and researches to enhance treatments for allergies, asthma, and recurrent infections. She specializes in allergic skin disorders, allergic rhinitis, drug allergies, food allergies/sensitivities, asthma, and recurrent infections.  Dr. Maitland holds an MD and PhD from the University of Pennsylvania and completed her residency in Internal Medicine at Brigham and Women's Hospital in Boston. She also pursued a Fellowship in Allergy and Immunology at Brigham and Women's Hospital and Mount Sinai Hospital in New York. More about Dr. Maitland:  https://www.metrodora.co/anne-maitland https://www.drannemaitland.net/dr-anne-maitland More resources about mast cell disease: Mast Cell Disease page: https://allergyasthmanetwork.org/health-a-z/mast-cell-diseases/ What is Anaphylaxis? https://allergyasthmanetwork.org/anaphylaxis/ What is Epinephrine? https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/ The Mast Cell Disease Society: https://tmsforacure.org/

The basic science of mast cells is the first episode in our 6-part series exploring Mast cell diseases. To start the series, we explore the intricate workings of mast cells by diving into how they work and what happens when something is off balance. Have you ever wondered what releases histamine and how this happens? Then this episode is for you! What we cover in our episode about mast cell disease: What are mast cells, and what do they do? What are the different types of mast cell diseases? Mastocytosis Mast Cell Activation Syndrome Hereditary Alpha-tryptasemia The 7 types of mastocytosis The cause of mast cell disease KIT gene mutation in Mastocytosis More resources about mast cell disease: Mast Cell Disease page: https://allergyasthmanetwork.org/health-a-z/mast-cell-diseases/ What is Anaphylaxis? https://allergyasthmanetwork.org/anaphylaxis/ What is Epinephrine? https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/ We thank Blueprint Medicines for sponsoring this podcast.

Join us on as we delve into the world of mast cell disorders, including the lesser-understood mast cell activation syndrome (MCAS). Our guest, Kara Wada, a board-certified academic adult and pediatric allergy, immunology, and lifestyle medicine physician, will shed light on the complexities of these conditions. We'll discuss diagnostic challenges, patient experiences, gender disparities in health care, and the need for increased research and understanding. Kara Wada is a board-certified academic adult and pediatric allergy, immunology, and lifestyle medicine physician. She is CEO and founder, The Crunchy Allergist and the Demystifying Inflammation Summit, and serves as the director of clinical content for Aila Health. She discusses the KevinMD article, "Challenges faced by patients with mast cell disorders." Our presenting sponsor is Nuance, a Microsoft company. Do you spend more time on administrative tasks like clinical documentation than you do with patients? You're not alone. Clinicians report spending up to two hours on administrative tasks for each hour of care provided. Nuance, a Microsoft company, is committed to helping clinicians restore the balance with Dragon Ambient eXperience – or DAX for short. DAX is an AI-powered, voice-enabled solution that helps physicians cut documentation time in half. DAX Copilot combines proven conversational and ambient AI with the most advanced generative AI in a mobile application that integrates directly with your existing workflows. DAX Copilot can be easily enabled within the workflow of the Dragon Medical application to bring the power of ambient technology to more clinicians faster while leveraging the proven and powerful capabilities used by over 550,000 physicians. Explore DAX Copilot today. Visit https://nuance.com/daxinaction to see a 12-minute DAX Copilot demo. Discover clinical documentation that writes itself and reclaim your work-life balance. VISIT SPONSOR → https://nuance.com/daxinaction SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended GET CME FOR THIS EPISODE → https://earnc.me/9SaEnz Powered by CMEfy.

Do you know that tiny cells in your body called mast cells can misbehave and cause a range of allergic reactions and symptoms? In this episode of the Becoming Immune Confident podcast, Dr. Kara Wada explores the topic of mast cell disorders. She discusses what mast cells are, how they misbehave, and what can be done to address the issue. Join Dr. Wada as she shares her expertise and provides valuable insights into bridging academia with the lived experiences of patients. Join us for this informative and enlightening episode as we unravel the mystery of mast cells and their surprising impact on our health. What if there's more to your body's response than meets the eye? EPISODE IN A GLANCE-What is a Mast Cell?-Clinical Sign & Symptoms of Mast Cells-Why should we care about Mast Cells?-Spectrum of Misbehaving Mast Cells-Mimickers of Mast Cell-Mast Cell Adjacent-Making the Diagnosis-What can we do about it?-What can we do about symptoms?-Trigger Warning/Avoidance-Investigative Treatments ABOUT DR KARA WADAQuadruple board-certified pediatric and adult allergy immunology & lifestyle medicine physician, Sjogren's patient and life coach shares her recipe for success combining anti-inflammatory lifestyle, trusting therapeutic relationships, modern medicine & our minds to harness our body's ability to heal. CONNECT WITH DR WADAWebsite → http://www.drkarawada.com/ LinkedIn → https://www.linkedin.com/in/crunchyallergist/ Instagram → https://www.instagram.com/crunchyallergist/ Facebook → https://www.facebook.com/CrunchyAllergist Twitter → https://twitter.com/CrunchyAllergy TikTok → https://www.tiktok.com/@crunchyallergist SUBSCRIBE TO NEWSLETTER → https://www.drkarawada.com/newsletter Get Dr. Kara's weekly dose of a naturally-minded and scientifically-grounded approach to immune system health. JOIN THE BECOMING IMMUNE CONFIDENT MEMBERSHIP! Feel confident, energetic, and more like that bad*** you used to be.Apply Here→ https://www.immuneconfident.com

We are exploring Mast Cell diseases with The Mast Cell Disease Society Executive Director, Jessica Fraser, as we learn about this organization, its mission, and in-depth resources available for everyone! Resources to keep you in the know from the podcast:Mast Cell Disease Society What Are Mast Cell Diseases?Mast Cell Disease Society Patient Resource GuideEmergency Medical Alert CardMast Cell Disease Society Emergency Room ResourcesSupport GroupsNutrition FAQFind A PhysicianClinical TrialsPatient Assistance ProgramsYou can find the FAACT Roundtable Podcast on Pandora, Apple Podcast, Spotify, Google Podcast, Stitcher, iHeart Radio, Podcast Chaser, Deezer, and Listen Notes.Follow us on Facebook, X, Instagram, Threads, LinkedIn, Pinterest, TikTok, and YouTube.Sponsored by: Blueprint MedicinesThanks for listening! FAACT invites you to discover more exciting food allergy resources at FoodAllergyAwareness.org!

Channel Favorite Bob Miller returns to sit down with Dr. Jill Carnahan to delve into a lesser-known pathway for Mast Cell Activation Syndrome (MCAS) and the detrimental effects of excess Qu. As a leading expert in functional medicine, Dr. Carnahan invites Bob Miller, a renowned researcher, to shed light on this often misunderstood condition. During the interview, Bob Miller reveals the fascinating role of the aryl hydrocarbon pathway in MCAS and how it can significantly impact one's health when not properly regulated. He explains the connection between excess Qu, a chemical compound found in certain foods and environmental toxins, and its influence on mast cell activation. Key points MCAS is common underlying cause of chronic complex disease and related to toxic load and infectious burden in our increasingly toxic world Why Aryl hydrocarbon's are more important than you think! This path is simulated by polycyclic aromatic hydrocarbons, arachidonic acid, mycotoxins and high homocysteine and causes weight gain, fatty liver and hyperglycemia/pre-diabetes Polycyclic aromatic hydrocarbons and dioxins are triggers to environmental toxicity and trigger the Aryl hydrocarbon receptor leading to increase inflammation and mast cell activation

Rebecca has type 1 diabetes, celiac, Hashimoto's Raynauds, Mast Cell and more. This BetterHelp link saves 10% on your first month of therapy Try delicious AG1 - Drink AG1.com/Juicebox Use code JUICEBOX to save 40% at Cozy Earth  Get Gvoke HypoPen CONTOUR NextGen smart meter and CONTOUR DIABETES app Learn about the Dexcom G6 and G7 CGM Go tubeless with Omnipod 5 or Omnipod DASH  Get your supplies from US MED  or call 888-721-1514 Learn about Touched By Type 1 Take the T1DExchange survey A full list of our sponsors  How to listen, disclaimer and more Apple Podcasts> Subscribe to the podcast today! The podcast is available on Spotify, Google Play, iHeartRadio, Radio Public, Amazon Music and all Android devices The show is now available as an Alexa skill. My type 1 diabetes parenting blog Arden's Day Listen to the Juicebox Podcast online Read my award winning memoir: Life Is Short, Laundry Is Eternal: Confessions of a Stay-At-Home Dad The Juicebox Podcast is a free show, but if you'd like to support the podcast directly, you can make a gift here or buy me a coffee. Thank you! Follow Scott on Social Media @JuiceboxPodcast Disclaimer - Nothing you hear on the Juicebox Podcast or read on Arden's Day is intended as medical advice. You should always consult a physician before making changes to your health plan.  If the podcast has helped you to live better with type 1 please tell someone else how to find the show and consider leaving a rating and review on Apple Podcasts. Thank you! The Juicebox Podcast is not a charitable organization.  

While mast cell diseases may be rare overall, patients with mast cell diseases such as mast cell activation syndrome and systemic mastocytosis often present with an atypical presentation which can be challenging for both the patient and provider. In this episode, Dr. Parikh interviews Erin Kolb, an Allergy Family Nurse Practitioner who specializes in mast cell diseases. They discuss symptoms, diagnostic tests and treatment options. 

In this episode, Jamie Kunkle together with Evan Hirsch, talk about Fatigue & Triad: Mast Cell Activation, Dysautonomia & Hypermobility Syndrome.   Dr. Jamie Kunkle has been practicing as a dual licensed Naturopathic Doctor and East Asian Medicine Practitioner (Acupuncturist) for 10 years. He specializes in Tickborne Illness, Lyme Disease, Long Haul Syndrome, Autoimmunity & Chronic Pain.   Dr. Kunkle received a Bachelors of Science in Neuroscience from the University of Pittsburgh, and a masters in acupuncture and traditional Chinese medicine and doctorate in Naturopathic Medicine from Bastyr University in Seattle, WA. He currently works at the Gordon Medical Associates in San Raphael, CA. Dr. Kunkle has two daughters that keep him very busy. He enjoys being in nature, working on his house and spending time with his wife whom is also a Naturopathic Doctor. He is also an electronic musician when he finds the time.   To learn more about Dr. Kunkle, please visit: https://gordonmedical.com/   .   For more information about Dr. Evan and his program, Click Here.   Prefer to watch on Youtube? Click Here.   Please note that any information in this episode is for educational purposes only and does not constitute medical advice.  

EMFs are a part of our daily environment, impacting individuals to varying degrees…   As our exposure increases, so does the potential for our susceptibility to EMFs to accumulate and for our rain barrel to fill up.   Those who experience heightened sensitivity, such as individuals with mast cell activation or elevated histamine levels, should prioritize reducing their exposure.   So today, on the latest episode of #CabralConcept 2790, I want to share with you the connection between EMFs & Mast Cell Histamine Sensitivities and provide ways that you can mitigate their impact in your life - Enjoy the show, and feel free to share your insights!   - - - For Everything Mentioned In Today's Show: StephenCabral.com/2790 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

It's so exciting when a familiar drug in one area shows promise as a new treatment for another health problem. Researchers and clinicians pay attention, especially when the drug is inexpensive and easily tolerated. Such is the case with Panacur (fenbendazole), a dewormer that has caught the attention of cancer researchers. It's early days of studying its effects on cancer, but some people want to start using it now! And no wonder. It's mechanism of action is the same one used by several well-known cancer drugs! But would the high doses needed cause the same kind of severe long-term effects of other chemo drugs we're already using? Dr. Lauren Barrow joins us for a fascinating discussion prompted by listener Tracie's question about her dog's mast cell tumors. We talk about the thinking general practitioners engage in around repurposing drugs for cancer … and why a trip to the oncologist might be a good idea. After all, oncologists (especially veterinary oncologists) are not just the keepers of insights and expertise about standard treatment methods … they are the researchers on the cutting edge of oncology. They're the ones who research and repurpose drugs! Links Mentioned in Today's Show: Podcast About Panacur (fenbendazole): https://www.dogcancer.com/podcast/drugs/panacur-for-cancer-in-dogs-dr-nancy-reese-qa/ Article about Mast Cell Tumors: https://www.dogcancer.com/articles/types-of-dog-cancer/mast-cell-tumors-in-dogs/ Article about Benadryl: https://www.dogcancer.com/articles/drugs/benadryl-for-dogs/ Article about oncologists Related Links: Podcast about Tagamet and Benadryl for Dogs: https://www.dogcancer.com/podcast/drugs/tagamet-and-benadryl-for-dogs-nancy-reese-dvm-mpvm-phd-deep-dive/ Chapters: 00:00 START                              00:58 Tracie's Call                    02:13 Worried About Chemotherapy; Are There Other Drugs?        02:54 Panacur for Mast Cell Tumors?            04:45 Other Drugs Kill Using Microtubules, Too: Chemotherapy Drugs       05:14 Any Drug Used to Kill Cancer May Have Side Effects, Even Repurposed Drugs          06:56 Any Other Repurposed Drugs for Mast Cell Tumors?  07:12 Mast Cells Are Immune Cells That Release Histamine 07:35 Give Benadryl to Help with Histamine Symptoms        08:56 Inflammatory Cascades Are Messy     10:46 Grade Three Mast Cell Tumors Are Serious     11:30 Find Out If There's Metastasis Already 11:54 This Is a Case for an Oncologist's Expertise      13:36 Do Oncologists Respect the Word No?            15:06 Chemotherapy in Humans Is Different 17:25 Oncologists Know More About Repurposed Drugs Because They Are the Researchers!       18:46 Cutting Edge Therapies Are at the Onc's Office           19:20 Palladia for Mast Cell Tumors  -- Get to know today's guest, Dr. Lauren Barrow: https://www.dogcancer.com/people/lauren-harper-barrow-dvm-cna/ For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Take Home Points: Airway management is paramount; expect a challenging intubation and consider controlling the airway early if there is apparent airway compromise. Understanding the cause of angioedema (mast cell vs. bradykinin mediated) helps dictate directed management. Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. REBEL Core Cast ... Read more The post REBEL Core Cast 108.0 – Angioedema appeared first on REBEL EM - Emergency Medicine Blog.

Have you noticed that your PMS mood symptoms are worsening the older you get? In this episode, I explain why this happens and what you can do about it. Connect with me on Instagram! Sign up for the Hormone Empowered Masterclass! Stop feeling like a victim of your hormones, and begin experiencing healing now! Schedule your Hormone Jumpstart Session! Podcast episode with my client, Heather Shuler: PMS Rage and Hating Your Hormones

Dr. Tom Fabian discusses Mast Cell Activation, Dysbiosis, and IBS at the Functional Medicine Discussion Group meeting on August 24, 2023 with moderator Dr. Ben Weitz.   [If you enjoy this podcast, please give us a rating and review on Apple Podcasts, so more people will find The Rational Wellness Podcast. Also check out the video version on my WeitzChiro YouTube page.]    Podcast Highlights 6:18  IBS is a condition that is diagnosed mainly by symptoms and these are part of the Rome IV Criteria.  [These are found at TheRomeFoundation.org]  There are four recognized subtypes of IBS: IBS-C (constipation), IBS-D (diarrhea), IBS-M (mixed), and IBS-U (undefined).  Bloating and distension are common symptoms associated with IBS, but they are not officially included in the Rome IV criteria.  There is no currently accepted test for the diagnosis of IBS.  This is a good review article on what we currently know about IBS: Camilleri M, Boeckxstaens G.  Irritable bowel syndrome: treatment based on pathophysiology and biomarkers.  Gut. 2023 Mar;72(3):590-599.    11:38  There are a number of conditions that result in similar symptoms to IBS, including Bile-acid malabsorption, exocrine pancreatic insufficiency, carbohydrate intolerance, SIBO, SIFO, Dyssynergic defecation, Ehlers-Danlos syndrome, mast cell activation syndrome, eosinophilic gastroenteritis, intra-abdominal adhesions, celiac disease, and giardiasis. Dr. Fabian noted that we are learning that a significant number of patients with IBS symptoms, esp. on the diarrhea side, have a sucrase-isomaltase deficiency, which is one of the brush border enzymes in the small intestine.  This leads to a malabsorption of sucrose and certain starches. 16:15  IBS Mechanisms.  Diet is an important factor since 85% of IBS patients report their symptoms are triggered by eating, often 60 min or so after eating.  Leaky gut is a factor in most GI conditions. We see immunoactivation/inflammation, though a more subtle form of inflammation than what we see with inflammatory bowel disease like Crohn's disease. This is where mast cells come into play. There is also the gut-brain axis. 18:12  Disorders of Gut-Brain Interaction.  The new name for functional GI disorders being adopted in research is Disorders of Gut-Brain Interaction.  This is a good review article on this:  Vanuytsel T, Bercik P, Boeckxstaens G.  Understanding neuroimmune interactions in disorders of gut–brain interaction: from functional to immune-mediated disorders  Gut 2023;72:787-798.   We see as part of the pathophysiology in IBS a subtle mucosal infiltration of immune cells, especially mast cells and eosinophils, along with the increased release of  nociceptive mediators, which lead to visceral hypersensitivity, which plays a role in abdominal pain. 22:20  The pathogenesis of IBS is explained well in the following article: Carco C, Young W, Gearry RB, Talley NJ, McNabb WC, Roy NC. Increasing Evidence That Irritable Bowel Syndrome and Functional Gastrointestinal Disorders Have a Microbial Pathogenesis. Front Cell Infect Microbiol. 2020 Sep 9;10:468.  Dysfunctional microbiota leads to increased intestinal permeability that leads to immune activation that results in mast cell activation and visceral hypersensitivity that leads to abdominal pain, bloating, and altered motility.                         Dr. Tom Fabian is a leading expert on the role of the microbiome in health, immune function, chronic disease and aging. He received his PhD in molecular biology from the University of Colorado Boulder, and he's worked as a biomedical researcher in the biotechnology industry and more recently as a consultant in the microbiome testing field.  Currently, Dr. Fabian serves as a consultant and science advisor with Diagnostic Solutions Lab. Tom's website is Microbiome Mastery.com.  Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorder...

Immune explains how mast cells, IgE antibody, and the brain collaborate to promote avoidance of certain foods to evade allergic responses. Hosts: Vincent Racaniello, Cynthia Leifer, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts. RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Mast cells and immune avoidance behavior (Nature) Immune sensing of food allergens promotes avoidance (Nature) Immunology that underlies picky eating (Nature) Time stamps by Jolene. Thanks! Music by Steve Neal. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv