Docs Who Lift

Learn what age-related macular degeneration (AMD) isWhat causes AMDThe types of AMDThe update on NAION - listen to last year's podcast all about itWhy we aren't too concernedClick here to join Dr. Spencer's online clinic VineyardClick to read the JAMA AMD articleClick to read the Ophthalmology journal AMD article

Menopausal hormonal therapy should not be a blanket recommendation for everyone going through menopauseWeight management in women is influenced by hormonal changes throughout life stages.Retrospective analyses can provide insights but have limitations.The wellness industry often oversimplifies complex medical issues.Hormonal replacement therapy may have subtle benefits for weight management.Confounding factors like SSRIs can complicate weight loss efforts.A holistic approach is essential for managing women's health during menopause.Education and awareness are crucial for women navigating menopause.Future research should focus on randomized controlled trials for better clarity.Understanding individual patient experiences is key to effective treatment.Click here to see her studyClick here to follow Dr. Tchang on XClick here to join Dr. Spencer's clinic Vineyard 

Dr. Grant Tinsley joins the discussion as the body composition expert.Myostatin is a key regulator of muscle growth.Wendy Whippete the most jacked muscled up dogThe concern of GLP-1 receptor agonists and muscle mass loss.Overview of Courage trial looking at semaglutide and trevogrumab and lean mass lossUpcoming Believe trial coming out (bimagrumab and semaglutide)Exercise remains crucial for muscle health and function.MRI data from SURPASS MRI provides new insights into muscle volume changes.The combination of medications may have varying effects on muscle mass.Caution is advised regarding the long-term effects of new drugs.Clinical benefits of medications often outweigh concerns about muscle loss.Future research will explore the synergy between exercise and medication.Other docs who lift podcasts with Dr. Grant:Tirzepatide muscle lossLean mass loss and GLP-1 meds

Takeaways:The MAHA report aims to address public health issues but lacks actionable policies.Historical context is crucial for understanding current dietary guidelines.Funding for nutrition research has been inadequate, impacting the quality of data.Public perception of nutrition often outpaces scientific evidence.The evolution of dietary guidelines reflects political and social influences.There is a need for more rigorous nutrition science to inform policy.The dietary guidelines have not significantly improved population health metrics.Political will is essential for implementing effective nutrition policies.Nutrition science faces challenges in funding and research infrastructure.The MAHA report's recommendations may be more performative than substantive. Food policy changes are often superficial and ineffective.There is a significant disconnect between policy and actual health outcomes.Nutrition science is underfunded and lacks high-quality research.Misinformation in nutrition can lead to harmful public health outcomes.The focus on food additives distracts from more pressing issues like obesity.Experts are being sidelined in favor of political agendas.Public trust in health recommendations has eroded post-COVID.Nutrition policies need to be based on solid scientific evidence.The food industry needs clearer guidance on reformulating products.Future nutrition policies must prioritize public health over political gainRead Dr. Kevin's paperFollow Dr. Kevin on instagramJoin Dr. Spencer's clinic

Click to read Joy PrescriptionsDrs. Karl and Spencer talk to Dr. Tiffany Moon all about Joy Prescriptions. Learn how to stop chasing perfection and embrace connection. 00:00Introduction to Dr. Tiffany Moon02:02Journey to Reality TV: The Real Housewives of Dallas05:58Life After Reality TV: Finding Joy and Purpose09:59The Joy Prescription: A New Approach to Life17:01Work-Life Integration: Balancing Career and Family22:09Empowering Women: The Lead Her Summit22:33Tiffany's Journey: From Childhood to Medical Success24:43The Quest for Joy: Breaking the Hedonic Treadmill26:42Finding Gratitude and Connection in Life28:37Coping Mechanisms: Humor and Self-Reflection29:57The Joy Prescription: A Path for High Achievers32:29Reconstructing Identity: Beyond External Validation35:37The Impact of Sports on Identity and Achievement40:54Closing Thoughts: Embracing Joy and Connection

Tirzepatide is more effective for weight loss than semaglutide.Cost-effectiveness is crucial in prescribing weight loss medications.Patients with severe obesity should receive more expensive medications for better outcomes.Both medications show significant benefits for obesity-related conditions.Long-term studies indicate sustained weight loss with both drugs.Gender differences affect weight loss outcomes with these medications.Safety profiles show tirzepatide may be better tolerated than semaglutide.The need for affordable drug pricing is emphasized.Clinical benefits extend beyond weight loss to include metabolic health.Future studies are needed to confirm cardiovascular benefits of tirzepatide.Click here to see the studyClick here to join Dr. Spencer's new online clinic

TakeawaysMASH is a significant obesity-related complication.Semaglutide shows promise in treating MASH.Weight loss is crucial for improving liver health.Bariatric surgery remains the most effective treatment.The Essence trial indicates a 63% resolution of NASH.New medications are being developed for obesity treatment.Early intervention is key to preventing severe liver damage.Accessibility of medications is a major concern.Comparative studies are essential for evaluating new treatments.Future treatments may include innovative delivery methods.Chapters00:00 Introduction to MASH and Semaglutide Study04:29 Understanding Metabolic Dysfunction and Its Implications08:02 Essence Trial: Semaglutide's Impact on MASH12:58 Comparative Analysis of New Treatments for MASH17:30 The Future of Obesity Treatment and Drug AccessibilityJoin Vineyard - Dr. Spencer's online clinicSee the study

Drs. Karl and Spencer chat with return guest Dr. Lauren Semple about creatine, protein, cortisol, fasting exercise, and training in women.Follow Dr. Lauren's instagramJoin Dr. Spencer's online clinic

Drs. Karl and Spencer discuss a new study looking at tirzepatide and metabolic rate. They also discuss a patient case of tirzepatide induced anhedonia.Here is the tirzepatide studyIf interested in joining Dr. Spencer's clinic Vineyard - Click Here 

Drs. Karl and Spencer discuss the claim that GLP-1 meds cause more fat cells.Learn about if and how GLP-1 meds increase fat cells and what that means along with other claims about these medicine.Join Dr. Spencer's online clinic that specializes in GLP-1 medicines

Drs. Karl and Spencer talk to Dr. Kenneth Qiu all about direct medical care - the future of medicine.Learn about how bypassing insurance and creating a relationship directly with a doctor can improve your health and save money in the long run.Follow Dr. Qiu on Linked inSee Dr. Spencer's direct care model with Vineyard

Drs. Karl and Spencer discuss with Dr. Grant Tinsley all about the new analysis of how much "lean mass" is lost with tirzepatide, the most powerful medicine available for weight loss.Learn:The difference between fat free mass and lean mass and lean soft tissue and muscle.If GLP-1 medicines cause muscle loss specificallyHow to minimize muscle loss when taking these medicinesOur new study together.Click here for the tirzepatide paperClick here to see Dr. Grant Tinsely's InstagramClick here to join Vineyard

Drs. Karl and Spencer discuss how bad the Hims and Hers ad was.From an outside perspective, the ad may have seemed good.But when you dig deeper, it was actually really bad.Listen to learn.Join Dr. Spencer's new online clinic - Vineyard.

Drs. Karl and Spencer chat with NMN and NAD expert Dr. Charles Brenner all about these supposed longevity supplements.Learn about NAD metabolismWhether it's worth supplementing or not with NAD or NMNFollow Dr. Brenner on Twitter

Drs. Karl and Spencer chat with Dr. Fatima Cody Stanford all about obesity, genetics, and her appearance on 60 minutes.Does Dr. Sanford believe lifestyle doesn't matter for obesity?Find out by listening!Watch Dr. Stanford's 60 minute clip Join Dr. Spencer's Obesity Clinic

Drs. Karl and Spencer chat about the new Lancet Commission's report on Clinical Obesity along with the new study on high dosed Wegovy. Learn:How 7.2 mg of Wegovy (semaglutide) compares to 2.4 mgWhat the proposed definitions of clinical and preclinical obesity areClick here to join Dr. Spencer's new online clinic

Drs. Karl and Spencer chat with Dr. Sowa about her book The Ozempic Revolution.Learn:Why she wrote the book.The top 3 things to know when starting a GLP-1 medicine.Also hear the top criticism from Drs. Karl and Spencer. You will laugh.Click here to get the bookIf you're on a GLP-1 currently and want to switch to Dr. Spencer's new clinic, Click Here

Drs. Karl and Spencer discuss the concept of "microdosing" GLP-1 receptor agonists along with talk about the new top line results from REDEFINE which studied the new drug CagriSema. 

Drs. Karl and Spencer chat with Dr. Lauren Colenso-Semple all about how the menstrual cycle and how it should affect your workout programming. Should you change your workouts around your menstrual cycle? Find out by listening! Check out her instagramRead her paper on exercise and menstrual cyclesRead her paper on protein synthesis throughout the menstrual cycle

Drs. Karl and Spencer discuss the topline results from Surmount 5 which put Zepbound (tirzepatide) against Wegovy (semaglutide) for weight loss. They also discuss some news around compounded GLP-1s.Learn:Weight loss and glycemic differences between tirzepatide and semaglutideWhat the FDA is thinking for compounded GLP-1sIf you're not on Dr. Spencer's virtual clinic waitlist, click here

Drs. Karl and Spencer chat with Dr. Shivani Misra, a metabolic specialist physician researcher from the UK, all about the various forms of diabetes mellitus.Learn:The types of diabetes mellitusThe monogenic forms (some what refer to as MODY)The differences within type 2 diabetesWhether CGMs (continuous glucose monitors) are usefulIf low carb could help someFollow Dr. Misra on X/Twitter 

Drs. Karl and Spencer chat with AtlasMD - Dr. Josh Umbehr all about making healthcare cheaper using direct primary care.Learn:How cheap labs and and meds should beHow cutting out the middlemen can help healthcare and decrease costsFind AtlasMD here

Drs. Karl and Spencer discuss the brand new 3 year study of tirzepatide in those with prediabetes along with a discussion on semaglutide treating osteoarthritis.Learn:If people lose weight and keep it off with tirzepatideHow many people regain weight after stopping the medicineLong-term side effectsIf semaglutide helps with osteoarthritisClick here to read the tirzepatide studyClick here to read the semaglutide study

Drs. Karl and Spencer invite Dr. Andrea Love back to the podcast to discuss a recent Joe Rogan podcast with Calley and Casey Means along with the concept of Make America Healthy Again and RFK jr.Learn:What the docs agree with.What they don't agree with.Is raw milk okay?Are cancer rates rising?and moreFollow Dr. Andrea here https://www.instagram.com/dr.andrealove

Drs. Karl and Spencer discuss all things cortisol and poke fun at the influencers who try to fear monger exercise due to cortisol increases.Learn:What is cortisol and what does it do?Is  cortisol bad?Should you worry about cortisol increases with exercise?Should you take supplements to lower cortisol?and more

Drs. Karl and Spencer discuss their ideal healthcare delivery system.Learn:Spencer's journey building and selling Sequence and what he wants to do next.How Dr. Karl believes healthcare should be and what he's doing next.Click here to get on Dr. Spencer's waitlist 

Drs. Karl and Spencer discuss BS supplements claiming to be like Ozempic along with discuss some new obesity drugs coming down the pipeline that were announced in phase 1 and 2 trials.Are there any supplements that can mimic Ozempic?What is amylin and how does it help with weight and sugars?What is this new oral drug "amycretin" in phase 1 trials?and more

Drs. Karl and Spencer chat with Dr. Jen Gunter all about menopause.Learn:How it's diagnosed.When and when not to treat.The various treatment.If it is indicated for cardiovascular disease prevention or body composition.Whether or not you should get labs.See more at Dr. Gunter's website 

Drs. Karl and Spencer talk about the top line results from study showing liraglutide may have some benefit in Alzheimer's along with top line results from the Summit trial showing heart failure benefits with tirzepatide.They also discuss the women's boxing controversy and BMI in athletes.

Drs. Karl and Spencer chat with return guest and bone expert endocrinologist Dr. Rachel Pessah-Pollack all about the new Vitamin D guidelines.Should healthy people even check a vitamin D level?Should they supplement with vitamin D?What people should check or supplement?Click here for the new guidelines 

Does semaglutide cause blindness?What is NAION (nonarteritic anterio ischemic optic neuropathy)?What about worsening of diabetic retinopathy with semaglutide?What can you do to minimize the risk of NAION and retinopathy?Get the full study hereRead Dr. Brugger's blog

Tirzepatide may be a good option if you have obesity and obstructive sleep apnea.Click here to read the study

Click here to read about the gastric ablation and trial.Click here to see Dr. McGowan's clinic

Drs. Karl and Spencer discuss the recent FLOW trial where semaglutide was found to be kidney protective. They also go off about the costs of these medicines and what to do (including compounding considerations). Click here to see the study

Drs. Karl and Spencer discuss the most recent South Park episode where GLP-1 medicines are discussed along with the dysfunctions of our healthcare system among other issues.

Drs. Karl and Spencer discuss the fallacies of functional medicine. You'll learn what functional medicine is and whether you should seek it out.

Drs. Karl and Spencer respond to Jillian Michaels on the Bill Maher show

Drs. Karl and Spencer discuss with gastroenterologist Dr. McGowan all about endoscopic gastroplasty. See recent study on cost effectiveness of endoscopic gastroplasty vs semaglutide Check out his program

Drs. Karl and Spencer discuss the new studies about GLP-1 medicines and Parkinson's and heart failure along with how these meds are not just weight loss drugs but health promoting medicines. Click here to see the Parkinson's study Click here to see the heart failure study

Drs. Karl and Spencer chat with Kasey Potts all about her journey with lipedema. Learn more about how this condition is diagnosed and treated. Check out her instagram

Drs. Karl and Spencer chat with Dr. Amron all about lipedema. He is a specialized surgeon who treats lipedema daily. Learn about diagnosing and treating this condition that is commonly mistaken with obesity. Check his sites https://www.dramronconsultations.com/ https://www.advancedlipedematreatment.com/

Drs. Karl and Spencer discuss a new study showcasing the importance of exercise during and after GLP-1 medicine use. Click here to see the original study Click here to see the extension study

Drs. Karl and Spencer discuss a recent Mark Hyman podcast where he perpetuated some myths about obesity and GLP-1 receptor agonist medicines.

Drs. Karl and Spencer discuss whether your doctor needs to look a certain way in order to be a good doctor.

Drs. Karl and Spencer chat with Drs. Jess and Andrea all about popular podcasters like Andrew Huberman etc. and the spread of pseudoscience.

Drs. Karl and Spencer chat about their now defunct supplement company along with the ethics of big pharma direct to consumer marketing (including influencers).

Drs. Karl and Spencer chat with Dr. Brianna Durand all about the pelvic floor and incontinence when lifting etc. empower.physio pelvicrehab.org

Drs. Karl and Spencer chat with Dr. Stuart Phillips all about protein. How much do you need to eat for optimal health and body composition and more!

Drs. Karl and Spencer chat with Dr. Nicola Guess all about the evidence behind using continuous glucose monitors in those without type 2 diabetes. Learn whether they are useful for even harmful Read her review paper here

Drs. Karl and Spencer discuss the new SELECT results that show a decrease in cardiovascular events in those taking Wegovy who have a history of cardiovascular disease. See trial below https://www.nejm.org/doi/full/10.1056/NEJMoa2307563

Drs. Karl and Spencer discuss how tirzepatide is now approved for obesity. Learn: When will it be available How much will is cost Any differences compared to Mounjaro Surmount 3 trial