Podcasts about Genetic variation

Hello everyone. Welcome to the latest episode of The Matchbox Podcast powered by Ignition Coach Co. I'm your host, Adam Saban, and on this week's episode we're discussing whether or not acclimatizing for altitude can be substituted with heat training and how to best execute VO2max intervals.   Today's show is also brought to you by Flow Formulas. Head over to flowformulas.com today to check out their full suite of endurance nutrition offerings and make sure to use the discount code “Matchbox” when checking out.   As always, if you like what you hear please share this with your friends and leave us a five star review and if you have any questions for the show drop us an email at matchboxpod@gmail.com with email title The Matchbox Podcast or head over to ignitioncoachco.com and fill out The Matchbox Podcast listener question form. Alight let's get into it!   For more social media content, follow along @ignitioncoachco @adamsaban6 @dizzle_dillman @dylanjawnson @kait.maddox   https://www.youtube.com/channel/UCnvEDN2A2ZjhNHb6uxh84PQ https://www.youtube.com/c/DylanJohnsonCycling https://www.ignitioncoachco.com  Intro/ Outro music by AlexGrohl - song "King Around Here" - https://pixabay.com/music/id-15045/    The following was generated using Riverside.fm AI technologies Summary The conversation discusses the use of heat acclimation as a substitute for altitude training. The coaches agree that heat acclimation can be a good alternative if altitude training is not possible. Both heat and altitude acclimation increase blood volume, which can help with performance at altitude. However, heat acclimation should not be seen as a replacement for altitude acclimation, as the effects are not as significant. The coaches also discuss the stress on the nervous system during heat and altitude acclimation, and the importance of managing intensity during workouts. They also touch on the genetic variation in response to altitude and the potential benefits of heat acclimation over altitude acclimation. The conversation then transitions to discussing VO2 max intervals and how to approach them. The coaches advise against taking breaks in the middle of intervals and recommend adjusting the power target if necessary. They also emphasize the importance of pacing and mental strategies to push through the challenging moments of VO2 max intervals. Keywords heat acclimation, altitude training, blood volume, nervous system, intensity, genetic variation, VO2 max intervals, pacing, mental strategies Takeaways Heat acclimation can be a substitute for altitude training if altitude acclimation is not possible. Both heat and altitude acclimation increase blood volume, which can benefit performance at altitude. Managing intensity during heat and altitude acclimation is important to avoid excessive stress on the nervous system. There is genetic variation in response to altitude, and individual differences should be considered when planning acclimation strategies. During VO2 max intervals, it is important to pace yourself and avoid taking breaks in the middle of intervals. Adjusting the power target and using mental strategies can help push through the challenging moments of VO2 max intervals. Titles Genetic Variation in Response to Altitude Heat Acclimation vs. Altitude Training: Pros and Cons Sound Bites "Heat acclimation and altitude acclimation increase blood volume." "The effects of heat and altitude acclimation are not as significant as altitude acclimation alone." "Adjusting the power target and using mental strategies can help push through the challenging moments of VO2 max intervals." Chapters 00:00 Heat Acclimation vs. Altitude Training 09:07 Managing Intensity and Stress during Acclimation 12:01 Genetic Variation in Response to Altitude 19:34 Approaching VO2 Max Intervals

In this episode, we discuss Autism with Dr. Leanna Hernandez. Dr. Hernandez is an Assistant Professor in the Department of Psychiatry and Biobehavioral Sciences at UCLA and director of the Hernandez Lab. She is a member of UCLA's Center for Autism Research and Treatment, Center for Neurobehavioral Genetics, and the Brain Research Institute, and serves as Co-Director of the Genetics, Genomics, and Informatics Core for UCLA's Intellectual and Developmental Disabilities Research Center.Hernandez Lab https://www.hernandezlabucla.orgAdditive effects of oxytocin receptor gene polymorphisms on reward circuitry in youth with autism https://www.nature.com/articles/mp2016209Imaging-genetics of sex differences in ASD: distinct effects of OXTR variants on brain connectivity https://www.nature.com/articles/s41398-020-0750-9Oxytocin and Vasopressin and the Autistic Phenotype https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000660031273 https://www.youtube.com/watch?v=DAtmC-s1_e0(0:00) Intro; Dr. Leanna Hernandez(2:24) Autistic Phenotypes(4:13) Dr. Hernandez education journey into Autism and the Hernandez Lab(9:03) 2017 Paper Oxytocin Receptor Gene, Common Genetic Variance, Single Nucleotide Polymorphisms (SNP), and Reward and Social Processing and the Nucleus Accumbens (NAc)(15:10) Differences in Brain Connectivity between Autistics and Non-Autistics(20:06) Social Cognition, Boy Bias in Autism; GENDAAR Consortium and Sex- and Diagnosis-Differences(21:48) GENDAAR(22:45) Boys versus Girls Connectivity involving the NAc with and without Autism(25:38) Different Connectivity correlated with Different ADOS scores for Repetitive Behaviors(26:35) Female Protective Effect for Autism; Camouflaging/Masking(30:19) The Assessment process for Girls and the Oxytocin Receptor Gene Sex Differences and Socialness and understanding the Boy Bias(32:48) Current Research and a Genome Wide approach and Polygenic Risk Scores(35:10) Oxytocin and Excitation/Inhibition(37:08) Sharing Information and Current Research(41:45) The Future of Autism Research(45:48) Reviews/Ratings and Contact Infoemail: info.fromthespectrum@gmail.comX: https://twitter.com/rps47586Facebook: https://www.facebook.com/fromthespectrum.podcast

In this episode, we are joined by Dr. Amy Dapper, an assistant professor in the Department of Biological Sciences, to talk about the Dapper Lab, the importance of studying evolutionary biology, and how students can get involved with research at Mississippi State University.

O uso de roupas é um comportamento moderno importante. Separe trinta minutinhos do seu dia e descubra com a Mila Massuda como se originou esse comportamento e como ele contribuiu para a expansão bem-sucedida dos humanos em latitudes mais altas eclimas frios.   Apresentação: Mila Massuda (@milamassuda) Roteiro: Mila Massuda (@milamassuda) e Emilio Garcia (@emilioblablalogia) Edição: @Matheus_Heredia, Clayton Heringer (@tocalivros) e Juscelino Filho (@canalmusicalia) Produção: Prof. Vítor Soares (@profvitorsoares) e BláBláLogia (@blablalogia) Gravado nos estúdios TocaCast   ‌Quer ir além dos trinta minutinhos e se aprofundar no mundo da Ecologia?   CURSO DE ECOLOGIA POR APENAS R$42,00  https://cursosdebiologia.hotmart.host/     REFERÊNCIAS:   D'ERRICO, F. et al. The origin and evolution of sewing technologies in Eurasia and North America. Journal of Human Evolution, v. 125, p. 71–86, 1 dez. 2018.   ELIASON, C. M. et al. Exceptional preservation and the fossil record of tetrapod integument. Proceedings of the Royal Society B: Biological Sciences, v. 284, n. 1862, p. 20170556, 6 set. 2017.   JABLONSKI, N. G. The evolution of human skin pigmentation involved the interactions of genetic, environmental, and cultural variables. Pigment Cell & Melanoma Research, v. 34, n. 4, p. 707–729, 4 maio 2021.   KITTLER, R.; KAYSER, M.; STONEKING, M. Molecular Evolution of Pediculus humanus and the Origin of Clothing. Current Biology, v. 13, n. 16, p. 1414–1417, 19 ago. 2003.   KOWALCZYK, A.; CHIKINA, M.; CLARK, N. Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness. eLife, v. 11, p. e76911, 7 nov. 2022.   LASISI, T. et al. Human scalp hair as a thermoregulatory adaptation. 22 jan. 2023.   LU, C. P. et al. Spatiotemporal antagonism in mesenchymal-epithelial signaling in sweat versus hair fate decision. Science, v. 354, n. 6319, 23 dez. 2016.   OCOBOCK, C. et al. Brown adipose tissue thermogenesis among a small sample of reindeer herders from sub-Arctic Finland. Journal of Physiological Anthropology, v. 41, n. 1, 20 abr. 2022.   PAGEL, M.; BODMER, W. A naked ape would have fewer parasites. Proceedings of the Royal Society of London. Series B: Biological Sciences, v. 270, n. suppl_1, 7 ago. 2003.‌   ROGERS, ALAN R.; ILTIS, D.; WOODING, S. Genetic Variation at the MC1R Locus and the Time since Loss of Human Body Hair. Current Anthropology, v. 45, n. 1, p. 105–108, fev. 2004.   ‌TOUPS, M. A. et al. Origin of Clothing Lice Indicates Early Clothing Use by Anatomically Modern Humans in Africa. Molecular Biology and Evolution, v. 28, n. 1, p. 29–32, 7 set. 2010.

Amander Clark, Ph.D., delves into crafting artificial ovaries for fertility and aging research. She stresses the importance of diversity in stem cell studies to ensure comprehensive findings. By assembling ovarian models from various genetic backgrounds, her team aims for inclusive representation in biomedical research, potentially offering insights into reproductive health and disease. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38334]

Amander Clark, Ph.D., delves into crafting artificial ovaries for fertility and aging research. She stresses the importance of diversity in stem cell studies to ensure comprehensive findings. By assembling ovarian models from various genetic backgrounds, her team aims for inclusive representation in biomedical research, potentially offering insights into reproductive health and disease. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38334]

Amander Clark, Ph.D., delves into crafting artificial ovaries for fertility and aging research. She stresses the importance of diversity in stem cell studies to ensure comprehensive findings. By assembling ovarian models from various genetic backgrounds, her team aims for inclusive representation in biomedical research, potentially offering insights into reproductive health and disease. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38334]

Amander Clark, Ph.D., delves into crafting artificial ovaries for fertility and aging research. She stresses the importance of diversity in stem cell studies to ensure comprehensive findings. By assembling ovarian models from various genetic backgrounds, her team aims for inclusive representation in biomedical research, potentially offering insights into reproductive health and disease. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38334]

Amander Clark, Ph.D., delves into crafting artificial ovaries for fertility and aging research. She stresses the importance of diversity in stem cell studies to ensure comprehensive findings. By assembling ovarian models from various genetic backgrounds, her team aims for inclusive representation in biomedical research, potentially offering insights into reproductive health and disease. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38334]

Daniel Geschwind, M.D., Ph.D., explains autism's genetic roots using a polygenic model, where multiple genes, including common variations, contribute to the risk. Geschwind stresses a continuum in social behavior, showcasing features like synesthesia and exceptional talents as part of human variation. Geschwind,emphasizes the complexity of autism, urging recognition of strengths and vulnerabilities in the spectrum of human cognition and behavior. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39166]

Daniel Geschwind, M.D., Ph.D., explains autism's genetic roots using a polygenic model, where multiple genes, including common variations, contribute to the risk. Geschwind stresses a continuum in social behavior, showcasing features like synesthesia and exceptional talents as part of human variation. Geschwind,emphasizes the complexity of autism, urging recognition of strengths and vulnerabilities in the spectrum of human cognition and behavior. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39166]

Daniel Geschwind, M.D., Ph.D., explains autism's genetic roots using a polygenic model, where multiple genes, including common variations, contribute to the risk. Geschwind stresses a continuum in social behavior, showcasing features like synesthesia and exceptional talents as part of human variation. Geschwind,emphasizes the complexity of autism, urging recognition of strengths and vulnerabilities in the spectrum of human cognition and behavior. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39166]

Daniel Geschwind, M.D., Ph.D., explains autism's genetic roots using a polygenic model, where multiple genes, including common variations, contribute to the risk. Geschwind stresses a continuum in social behavior, showcasing features like synesthesia and exceptional talents as part of human variation. Geschwind,emphasizes the complexity of autism, urging recognition of strengths and vulnerabilities in the spectrum of human cognition and behavior. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39166]

Daniel Geschwind, M.D., Ph.D., explains autism's genetic roots using a polygenic model, where multiple genes, including common variations, contribute to the risk. Geschwind stresses a continuum in social behavior, showcasing features like synesthesia and exceptional talents as part of human variation. Geschwind,emphasizes the complexity of autism, urging recognition of strengths and vulnerabilities in the spectrum of human cognition and behavior. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39166]

Daniel Geschwind, M.D., Ph.D., explains autism's genetic roots using a polygenic model, where multiple genes, including common variations, contribute to the risk. Geschwind stresses a continuum in social behavior, showcasing features like synesthesia and exceptional talents as part of human variation. Geschwind,emphasizes the complexity of autism, urging recognition of strengths and vulnerabilities in the spectrum of human cognition and behavior. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39166]

Daniel Geschwind, M.D., Ph.D., explains autism's genetic roots using a polygenic model, where multiple genes, including common variations, contribute to the risk. Geschwind stresses a continuum in social behavior, showcasing features like synesthesia and exceptional talents as part of human variation. Geschwind,emphasizes the complexity of autism, urging recognition of strengths and vulnerabilities in the spectrum of human cognition and behavior. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39166]

Ruff Diesel  @RuffDiesel (aka Terrence Ruffin) is a 2x Arnold Classic Champ, 2x Mr. Olympia Runner Up,  and 5th place of Mr. Olympia 2023.Please share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.Watch The Podcast:https://www.youtube.com/channel/UCqgN2kieCEHwZ9M-QFBxfCgPharma TRT, GH analogs, peptides, IGF-1, var troche, fat-loss/hair-loss treatments, etc | HRT Men's Health Optimization: https://transcendcompany.com/patient-intake-form/?ls=Nyle+NaygaHuge Elements Line (astragalus, citrus bergamot, etc): https://hugesupplements.com/collections/elementsCode 'NYLE' for 10% off - proceeds go towards upgrading content productionHuge Supplements (Protein, Pre, Utilize, Vital): https://hugesupplements.com/?aff=165Support code 'NYLE' 10% offYoungLA Clothes: https://www.youngla.com/discount/nyleYoungLA For Her: https://www.youngla.com/collections/all-products-1/For-HerCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/transparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastCoaching | Personalized program:  https://www.nylenaygafitness.comTimestamps:00:00:00 - Teaser & Introduction00:01:36 - Time Management in Bodybuilding Prep and Off-Season Maintenance00:09:51 - Optimal Body Fat Percentage and Waist Management in Bodybuilding00:19:20 - The Influence of Genetics and Steroids on Muscle Building and Nutrition 00:25:47 - From Special Forces Training to Bodybuilding00:31:46 - Bodybuilding Journey: From Weightlifting at 13 to Early Gains and Diet Strategies00:36:53 - Discussion on Starting Lifting Young and Dealing with Health Issues00:42:43 - Strengths and Weaknesses of Bodybuilders in Classic Physique00:48:52 - Top 5 Exercises for Long-Term Training00:54:12 - Impact of Genetic Variation and Quality of Supplements in Bodybuilding01:02:35 - Off-Season Steroid Dosages and the Ageless Physique of Pro Bodybuilders01:06:36 - Q & A : Questions From The Audience01:33:56 - The End #psychology #stories #podcast #mentalhealth #discipline #selfdevelopment #personaldevelopment #fitness #ifbbpro #npc #bodybuilder #bodybuilding #tiktok #shizzy #olympia #mrolympia #2023olympia #selfimprovement #workout #gym #nutrition #mensphysique #classicphysique #love #discipline #relationships #chrisbumstead #tren #workout #gym #trt #hormones #discipline #hardstyle #steroids #larrywheels #bodybuilding #peptides fitness trt hormones personal development

Dr. Corey Watson is an Associate Professor at the University of Louisville. His work focuses on characterising and cataloguing antibody genetic diversity in human and mouse to better understand disease susceptibility and clinical health outcomes. Dr. William Lees is a researcher at University of London. His work focuses on developing Adaptive Immune Receptor (AIR) reference sets for diverse species and the annotation of experimental sequence data. In this episode we talk about the recent work by the Germline Database Working Group of the AIRR-Community. The accuracy of V and J gene segment assignment improves with the quality of the reference germline set. The accurate assignment is critical for characterization of somatic hypermutation. We discuss the challenges in creating a database to hold all relevant and potentially relevant germline information, especially in the light of increased discovery rate through technological advances and improved analysis pipelines. We also reflect on the complexity in handling personalised germline reference sets. The episode is hosted by Dr. Ulrik Stervbo and Dr. Zhaoqing Ding. Comments are welcome to the inbox of onairr@airr-community.org  or on social media under the tag #onAIRR. Further information can be found here: https://www.antibodysociety.org/the-airr-community/airr-c-podcast.  Website of the AIRR-C Germline Database Working Group https://www.antibodysociety.org/the-airr-community/airr-working-groups/germline_database/  Papers mentioned Collins, Andrew M., Mats Ohlin, Martin Corcoran, James M. Heather, Duncan Ralph, Mansun Law, Jesus Martínez-Barnetche, et al. 2023. “AIRR-C Human IG Reference Sets: Curated Sets of Immunoglobulin Heavy and Light Chain Germline Genes.” BioRxiv. https://doi.org/10.1101/2023.09.01.555348  Rodriguez, Oscar L., Yana Safonova, Catherine A. Silver, Kaitlyn Shields, William S. Gibson, Justin T. Kos, David Tieri, et al. 2023. “Genetic Variation in the Immunoglobulin Heavy Chain Locus Shapes the Human Antibody Repertoire.” Nature Communications 14 (1). https://doi.org/10.1038/s41467-023-40070-x  Lees, William D., Scott Christley, Ayelet Peres, Justin T. Kos, Brian Corrie, Duncan Ralph, Felix Breden, et al. 2023. “AIRR Community Curation and Standardised Representation for Immunoglobulin and T Cell Receptor Germline Sets.” Immunoinformatics (Amsterdam, Netherlands) 10 (100025): 100025. https://doi.org/10.1016/j.immuno.2023.100025  Jackson, Katherine J. L., Justin T. Kos, William Lees, William S. Gibson, Melissa Laird Smith, Ayelet Peres, Gur Yaari, et al. 2022. “A BALB/c IGHV Reference Set, Defined by Haplotype Analysis of Long-Read VDJ-C Sequences From F1 (BALB/c x C57BL/6) Mice.” Frontiers in Immunology 13. https://doi.org/10.3389/fimmu.2022.888555  Ford, Easton E., David Tieri, Oscar L. Rodriguez, Nancy J. Francoeur, Juan Soto, Justin T. Kos, Ayelet Peres, et al. 2023. “FLAIRR-Seq: A Method for Single-Molecule Resolution of near Full-Length Antibody H Chain Repertoires.” The Journal of Immunology 210 (10): 1607–19. https://doi.org/10.4049/jimmunol.2200825  Omer, Aviv, Ayelet Peres, Oscar L. Rodriguez, Corey T. Watson, William Lees, Pazit Polak, Andrew M. Collins, and Gur Yaari. 2022. “T Cell Receptor Beta Germline Variability Is Revealed by Inference from Repertoire Data.” Genome Medicine 14 (1). https://doi.org/10.1186/s13073-021-01008-4  Rodriguez, Oscar L., Catherine A. Silver, Kaitlyn Shields, Melissa L. Smith, and Corey T. Watson. 2022. “Targeted Long-Read Sequencing Facilitates Phased Diploid Assembly and Genotyping of the Human T Cell Receptor Alpha, Delta, and Beta Loci.” Cell Genomics 2 (12): 100228. https://doi.org/10.1016/j.xgen.2022.100228  Tools mentioned TIgGER (Immcantation) https://tigger.readthedocs.io/en/stable  IgDiscover https://github.com/NBISweden/IgDiscover  Partis https://github.com/psathyrella/partis MiXCR https://mixcr.com

This month, the genetic variants inherited from millions of years back that protect from disease but can cause illnesses; also, signs that we trust human-sourced information more than what a computer might say, how the whiff of a female can make some mice live longer, what bird's eggs can tell us about dinosaurs, and how taking a leaf out of "doughnut economics" can help academics combat the climate crisis... Get the references and the transcripts for this programme from the Naked Scientists website

Drei Gläser Milch sollte jeder Mensch am Tag für eine gesunde Ernährung zu sich nehmen - so hieß es jedenfalls lange! Doch in den vergangenen Jahren haben immer mehr Menschen aufgehört, Milch und Milchprodukte zu konsumieren, viele von ihnen aus Tierwohlgründen. Wissenschaftsjournalistin Yasmin Appelhans hat sich die Forschung rund um das Thema Milch angesehen. Im Gespräch mit Host Maja Bahtijarević erklärt sie, warum Menschen überhaupt einmal angefangen haben, Milch zu trinken und was sich dadurch für sie verändert hat. Außerdem geht es darum, ob Milch wirklich gesund ist oder nicht sogar krank machen kann - und um die Frage, wie sich unser Milchkonsum eigentlich auf das Klima auswirkt. Und wir fragen uns: Können Maske-tragende Kühe ihren Teil zum Klimaschutz beitragen?  DIE HINTERGRUNDINFORMATIONEN • Entwicklung des Milchkonsums in der Eurasischen Steppe: Jeong C, Wilkin S, Amgalantugs T, Bouwman AS, Taylor WTT, Hagan RW, et al. Bronze Age population dynamics and the rise of dairy pastoralism on the eastern Eurasian steppe. Proceedings of the National Academy of Sciences. 2018;115(48): E11248–E11255. https://doi.org/10.1073/pnas.1813608115 • Milchverbrauch pro Kopf und Land: Per capita milk consumption. https://ourworldindata.org/grapher/per-capita-milk-consumption [Abgerufen am 1. März 2023] • Konsum von Milch und Milchprodukten in Deutschland: BMEL-Statistik: Milch und Milcherzeugnisse. https://www.bmel-statistik.de/ernaehrung-fischerei/versorgungsbilanzen/milch-und-milcherzeugnisse [Abgerufen am 15. März 2023] • Regionale Unterschied bei Laktoseintoleranz: Storhaug CL, Fosse SK, Fadnes LT. Country, regional, and global estimates for lactose malabsorption in adults: a systematic review and meta-analysis. The Lancet Gastroenterology & Hepatology. 2017;2(10): 738–746. https://doi.org/10.1016/S2468-1253(17)30154-1 • Milchkonsum im östlichen Afrika: Bleasdale M, Richter KK, Janzen A, Brown S, Scott A, Zech J, et al. Ancient proteins provide evidence of dairy consumption in eastern Africa. Nature Communications. 2021;12(1): 632. https://doi.org/10.1038/s41467-020-20682-3 • Laktasepersistenz in Sudan: Hollfelder N, Babiker H, Granehäll L, Schlebusch CM, Jakobsson M. The Genetic Variation of Lactase Persistence Alleles in Sudan and South Sudan. Genome Biology and Evolution. 2021;13(5): evab065. https://doi.org/10.1093/gbe/evab065 • Bericht zu Milch als Nahrungsmittel vom Max Rubner-Institut 2014: Max Rubner-Institut. Ernährungsphysiologische Bewertung von Milch und Milchprodukten und ihren Inhaltsstoffen: Bericht für das Kompetenzzentrum für Ernährung, Bayern November 2014. 2014 Nov [Accessed 29th March 2023]. https://www.openagrar.de/receive/openagrar_mods_00016213 [Abgerufen am 29. März 2023] • Veröffentlichung zu Milch als Nahrungsmittel 2018: Watzl MP Bernhard. Gesundheitliche Bewertung von Milch und Milchprodukten und ihren Inhaltsstoffen. Ernaehrungs Umschau International. 2018;2/2018: 22–33. https://doi.org/10.4455/eu.2018.006 • Veröffentlichung mit Theorie zur Entstehung von Krebs vom Nobelpreisträger zur Hausen: zur Hausen H. Red meat consumption and cancer: reasons to suspect involvement of bovine infectious factors in colorectal cancer. International Journal of Cancer. 2012;130(11): 2475–2483. https://doi.org/10.1002/ijc.27413 • Stellungnahme zu Bovine Meat and Milk Factors des Bundesintituts für Risikobewertung: Bundesinstitut Für Risikobewertung. Neue Erkenntnisse zu „Bovine Meat and Milk Factors“ (BMMF): Stellungnahme Nr. 036/2022 des BfR vom 30. November 2022. BfR-Stellungnahmen. 2022;2022: no. 036. https://doi.org/10.17590/20221130-121559 • Website mit seltsamen Korrelationen: Spurious correlations. http://tylervigen.com/spurious-correlations [Abgerufen am 4. März 2023] • Projekt InnoRind mit Forschung zur umweltfreundlichen und tierfreundlichen Rinderhaltung: Projekt InnoRind. https://www.innorind.uni-kiel.de/de [Abgerufen am 29. März 2023] • Informationen Für Landwirt*innen zur klimafreundlichen und stickstoffarmen Fütterung von Milchvieh: Fütterungsmonitoring. https://infothek.die-milchkontrolle.de/elearning/fuetterungsmonitoring/ [Abgerufen am 29. März 2023] • Zugabe zu Gülle kann Methanausstoß reduzieren: Holtkamp F, Clemens J, Trimborn M. Calcium cyanamide reduces methane and other trace gases during long-term storage of dairy cattle and fattening pig slurry. Waste Management. 2023;161: 61–71. https://doi.org/10.1016/j.wasman.2023.02.018 • Umweltfreundlichkeit verschiedener Milchersatzprodukte gegenüber Kuhmilch (Our Word in Data): Environmental footprints of dairy and plant-based milks. https://ourworldindata.org/grapher/environmental-footprint-milks [Abgerufen am 1. März 2023] • Informationen zur kuhgebundenen Kälberaufzucht: Thünen-Institut, Kuhgebundene Kälberaufzucht. https://www.thuenen.de/de/themenfelder/nutztierhaltung-und-aquakultur/kuhgebundene-kaelberaufzucht# [Abgerufen am 29. März 2023]

Drei Gläser Milch sollte jeder Mensch am Tag für eine gesunde Ernährung zu sich nehmen - so hieß es jedenfalls lange! Doch in den vergangenen Jahren haben immer mehr Menschen aufgehört, Milch und Milchprodukte zu konsumieren, viele von ihnen aus Tierwohlgründen. Wissenschaftsjournalistin Yasmin Appelhans hat sich die Forschung rund um das Thema Milch angesehen. Im Gespräch mit Host Maja Bahtijarević erklärt sie, warum Menschen überhaupt einmal angefangen haben, Milch zu trinken und was sich dadurch für sie verändert hat. Außerdem geht es darum, ob Milch wirklich gesund ist oder nicht sogar krank machen kann - und um die Frage, wie sich unser Milchkonsum eigentlich auf das Klima auswirkt. Und wir fragen uns: Können Maske-tragende Kühe ihren Teil zum Klimaschutz beitragen?  DIE HINTERGRUNDINFORMATIONEN • Entwicklung des Milchkonsums in der Eurasischen Steppe: Jeong C, Wilkin S, Amgalantugs T, Bouwman AS, Taylor WTT, Hagan RW, et al. Bronze Age population dynamics and the rise of dairy pastoralism on the eastern Eurasian steppe. Proceedings of the National Academy of Sciences. 2018;115(48): E11248–E11255. https://doi.org/10.1073/pnas.1813608115 • Milchverbrauch pro Kopf und Land: Per capita milk consumption. https://ourworldindata.org/grapher/per-capita-milk-consumption [Abgerufen am 1. März 2023] • Konsum von Milch und Milchprodukten in Deutschland: BMEL-Statistik: Milch und Milcherzeugnisse. https://www.bmel-statistik.de/ernaehrung-fischerei/versorgungsbilanzen/milch-und-milcherzeugnisse [Abgerufen am 15. März 2023] • Regionale Unterschied bei Laktoseintoleranz: Storhaug CL, Fosse SK, Fadnes LT. Country, regional, and global estimates for lactose malabsorption in adults: a systematic review and meta-analysis. The Lancet Gastroenterology & Hepatology. 2017;2(10): 738–746. https://doi.org/10.1016/S2468-1253(17)30154-1 • Milchkonsum im östlichen Afrika: Bleasdale M, Richter KK, Janzen A, Brown S, Scott A, Zech J, et al. Ancient proteins provide evidence of dairy consumption in eastern Africa. Nature Communications. 2021;12(1): 632. https://doi.org/10.1038/s41467-020-20682-3 • Laktasepersistenz in Sudan: Hollfelder N, Babiker H, Granehäll L, Schlebusch CM, Jakobsson M. The Genetic Variation of Lactase Persistence Alleles in Sudan and South Sudan. Genome Biology and Evolution. 2021;13(5): evab065. https://doi.org/10.1093/gbe/evab065 • Bericht zu Milch als Nahrungsmittel vom Max Rubner-Institut 2014: Max Rubner-Institut. Ernährungsphysiologische Bewertung von Milch und Milchprodukten und ihren Inhaltsstoffen: Bericht für das Kompetenzzentrum für Ernährung, Bayern November 2014. 2014 Nov [Accessed 29th March 2023]. https://www.openagrar.de/receive/openagrar_mods_00016213 [Abgerufen am 29. März 2023] • Veröffentlichung zu Milch als Nahrungsmittel 2018: Watzl MP Bernhard. Gesundheitliche Bewertung von Milch und Milchprodukten und ihren Inhaltsstoffen. Ernaehrungs Umschau International. 2018;2/2018: 22–33. https://doi.org/10.4455/eu.2018.006 • Veröffentlichung mit Theorie zur Entstehung von Krebs vom Nobelpreisträger zur Hausen: zur Hausen H. Red meat consumption and cancer: reasons to suspect involvement of bovine infectious factors in colorectal cancer. International Journal of Cancer. 2012;130(11): 2475–2483. https://doi.org/10.1002/ijc.27413 • Stellungnahme zu Bovine Meat and Milk Factors des Bundesintituts für Risikobewertung: Bundesinstitut Für Risikobewertung. Neue Erkenntnisse zu „Bovine Meat and Milk Factors“ (BMMF): Stellungnahme Nr. 036/2022 des BfR vom 30. November 2022. BfR-Stellungnahmen. 2022;2022: no. 036. https://doi.org/10.17590/20221130-121559 • Website mit seltsamen Korrelationen: Spurious correlations. http://tylervigen.com/spurious-correlations [Abgerufen am 4. März 2023] • Projekt InnoRind mit Forschung zur umweltfreundlichen und tierfreundlichen Rinderhaltung: Projekt InnoRind. https://www.innorind.uni-kiel.de/de [Abgerufen am 29. März 2023] • Informationen Für Landwirt*innen zur klimafreundlichen und stickstoffarmen Fütterung von Milchvieh: Fütterungsmonitoring. https://infothek.die-milchkontrolle.de/elearning/fuetterungsmonitoring/ [Abgerufen am 29. März 2023] • Zugabe zu Gülle kann Methanausstoß reduzieren: Holtkamp F, Clemens J, Trimborn M. Calcium cyanamide reduces methane and other trace gases during long-term storage of dairy cattle and fattening pig slurry. Waste Management. 2023;161: 61–71. https://doi.org/10.1016/j.wasman.2023.02.018 • Umweltfreundlichkeit verschiedener Milchersatzprodukte gegenüber Kuhmilch (Our Word in Data): Environmental footprints of dairy and plant-based milks. https://ourworldindata.org/grapher/environmental-footprint-milks [Abgerufen am 1. März 2023] • Informationen zur kuhgebundenen Kälberaufzucht: Thünen-Institut, Kuhgebundene Kälberaufzucht. https://www.thuenen.de/de/themenfelder/nutztierhaltung-und-aquakultur/kuhgebundene-kaelberaufzucht# [Abgerufen am 29. März 2023]

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.03.01.530170v1?rss=1 Authors: Tichelman, N. L., Foerges, A. L., Elmenhorst, E.-M., Lange, D., Hennecke, E., Baur, D. M., Beer, S., Kroll, T., Neumaier, B., Bauer, A., Landolt, H.-P., Aeschbach, D., Elmenhorst, D. Abstract: The EEG alpha rhythm (8-13 Hz) is one of the most salient human brain activity rhythms. Spectral power in the alpha range in wakefulness and sleep varies among individuals based on genetical predisposition, yet knowledge about the underlying genes is scarce. The EEG alpha oscillations are related to cerebral energy metabolism and modulated by the level of attention and vigilance. The neuromodulator adenosine is directly linked to energy metabolism as product of adenosine tri-phosphate (ATP) breakdown and acts as a sleep promoting molecule by activitating A1 and A2A adenosine receptors. We quantified EEG oscillatory alpha power in wakefulness and sleep, as well as A1 adenosine receptor availability by positron emission tomography with 18F-CPFPX, in a large sample of healthy volunteers carrying different alleles of gene variant rs5751876 of ADORA2A encoding A2A adenosine receptors. Oscillatory alpha power was higher in homozygous C-allele carriers (n = 27, 11 females) compared to heterozygous and homozygous carriers of the T-allele (n(C/T) = 23, n(T/T) = 5, 13 females) (F(18,37) = 2.35, p = 0.014, Wilk's Lambda = 0.487). Across considered brain regions an effect of ADORA2A genotype on A1 adenosine receptor binding potential was found (F(18,40) = 2.62, p = 0.006, Wilk's Lambda = 0.459) and after correction for multiple testing this effect was shown to be significant for circumscribed occipital region of calcarine fissures. A correlation between individual differences in oscillatory alpha power and adenosine receptor availability was found for the subgroup of female participants only. In conclusion: a genetic variation in the adenosinergic system affects individual alpha power, although a direct modulatory effect via the A1AR has been demonstrated for females only. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Africa is thought to be the ancestral homeland of all modern human populations within the past 300,000 years. It is also a region of tremendous cultural, linguistic, climatic, and genetic diversity. Despite the important role that African populations have played in human history, they remain one of the most underrepresented groups in human genomics studies. A comprehensive knowledge of patterns of variation in African genomes is critical for a deeper understanding of human genomic diversity, the identification of functionally important genetic variation, the genetic basis of adaptation to diverse environments and diets, and the origins of modern humans. We have characterized genomic variation in thousands of ethnically and geographically diverse Africans in order to reconstruct human population history and local adaptation to variable environments and have identified candidate loci that play a role in alcohol metabolism and skin color. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Education] [Show ID: 38304]

Africa is thought to be the ancestral homeland of all modern human populations within the past 300,000 years. It is also a region of tremendous cultural, linguistic, climatic, and genetic diversity. Despite the important role that African populations have played in human history, they remain one of the most underrepresented groups in human genomics studies. A comprehensive knowledge of patterns of variation in African genomes is critical for a deeper understanding of human genomic diversity, the identification of functionally important genetic variation, the genetic basis of adaptation to diverse environments and diets, and the origins of modern humans. We have characterized genomic variation in thousands of ethnically and geographically diverse Africans in order to reconstruct human population history and local adaptation to variable environments and have identified candidate loci that play a role in alcohol metabolism and skin color. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Education] [Show ID: 38304]

Africa is thought to be the ancestral homeland of all modern human populations within the past 300,000 years. It is also a region of tremendous cultural, linguistic, climatic, and genetic diversity. Despite the important role that African populations have played in human history, they remain one of the most underrepresented groups in human genomics studies. A comprehensive knowledge of patterns of variation in African genomes is critical for a deeper understanding of human genomic diversity, the identification of functionally important genetic variation, the genetic basis of adaptation to diverse environments and diets, and the origins of modern humans. We have characterized genomic variation in thousands of ethnically and geographically diverse Africans in order to reconstruct human population history and local adaptation to variable environments and have identified candidate loci that play a role in alcohol metabolism and skin color. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Education] [Show ID: 38304]

Africa is thought to be the ancestral homeland of all modern human populations within the past 300,000 years. It is also a region of tremendous cultural, linguistic, climatic, and genetic diversity. Despite the important role that African populations have played in human history, they remain one of the most underrepresented groups in human genomics studies. A comprehensive knowledge of patterns of variation in African genomes is critical for a deeper understanding of human genomic diversity, the identification of functionally important genetic variation, the genetic basis of adaptation to diverse environments and diets, and the origins of modern humans. We have characterized genomic variation in thousands of ethnically and geographically diverse Africans in order to reconstruct human population history and local adaptation to variable environments and have identified candidate loci that play a role in alcohol metabolism and skin color. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Education] [Show ID: 38304]

Africa is thought to be the ancestral homeland of all modern human populations within the past 300,000 years. It is also a region of tremendous cultural, linguistic, climatic, and genetic diversity. Despite the important role that African populations have played in human history, they remain one of the most underrepresented groups in human genomics studies. A comprehensive knowledge of patterns of variation in African genomes is critical for a deeper understanding of human genomic diversity, the identification of functionally important genetic variation, the genetic basis of adaptation to diverse environments and diets, and the origins of modern humans. We have characterized genomic variation in thousands of ethnically and geographically diverse Africans in order to reconstruct human population history and local adaptation to variable environments and have identified candidate loci that play a role in alcohol metabolism and skin color. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Education] [Show ID: 38304]

Africa is thought to be the ancestral homeland of all modern human populations within the past 300,000 years. It is also a region of tremendous cultural, linguistic, climatic, and genetic diversity. Despite the important role that African populations have played in human history, they remain one of the most underrepresented groups in human genomics studies. A comprehensive knowledge of patterns of variation in African genomes is critical for a deeper understanding of human genomic diversity, the identification of functionally important genetic variation, the genetic basis of adaptation to diverse environments and diets, and the origins of modern humans. We have characterized genomic variation in thousands of ethnically and geographically diverse Africans in order to reconstruct human population history and local adaptation to variable environments and have identified candidate loci that play a role in alcohol metabolism and skin color. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Education] [Show ID: 38304]

Africa is thought to be the ancestral homeland of all modern human populations within the past 300,000 years. It is also a region of tremendous cultural, linguistic, climatic, and genetic diversity. Despite the important role that African populations have played in human history, they remain one of the most underrepresented groups in human genomics studies. A comprehensive knowledge of patterns of variation in African genomes is critical for a deeper understanding of human genomic diversity, the identification of functionally important genetic variation, the genetic basis of adaptation to diverse environments and diets, and the origins of modern humans. We have characterized genomic variation in thousands of ethnically and geographically diverse Africans in order to reconstruct human population history and local adaptation to variable environments and have identified candidate loci that play a role in alcohol metabolism and skin color. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Education] [Show ID: 38304]

Africa is thought to be the ancestral homeland of all modern human populations within the past 300,000 years. It is also a region of tremendous cultural, linguistic, climatic, and genetic diversity. Despite the important role that African populations have played in human history, they remain one of the most underrepresented groups in human genomics studies. A comprehensive knowledge of patterns of variation in African genomes is critical for a deeper understanding of human genomic diversity, the identification of functionally important genetic variation, the genetic basis of adaptation to diverse environments and diets, and the origins of modern humans. We have characterized genomic variation in thousands of ethnically and geographically diverse Africans in order to reconstruct human population history and local adaptation to variable environments and have identified candidate loci that play a role in alcohol metabolism and skin color. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Education] [Show ID: 38304]

Africa is thought to be the ancestral homeland of all modern human populations within the past 300,000 years. It is also a region of tremendous cultural, linguistic, climatic, and genetic diversity. Despite the important role that African populations have played in human history, they remain one of the most underrepresented groups in human genomics studies. A comprehensive knowledge of patterns of variation in African genomes is critical for a deeper understanding of human genomic diversity, the identification of functionally important genetic variation, the genetic basis of adaptation to diverse environments and diets, and the origins of modern humans. We have characterized genomic variation in thousands of ethnically and geographically diverse Africans in order to reconstruct human population history and local adaptation to variable environments and have identified candidate loci that play a role in alcohol metabolism and skin color. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Education] [Show ID: 38304]

Africa is thought to be the ancestral homeland of all modern human populations within the past 300,000 years. It is also a region of tremendous cultural, linguistic, climatic, and genetic diversity. Despite the important role that African populations have played in human history, they remain one of the most underrepresented groups in human genomics studies. A comprehensive knowledge of patterns of variation in African genomes is critical for a deeper understanding of human genomic diversity, the identification of functionally important genetic variation, the genetic basis of adaptation to diverse environments and diets, and the origins of modern humans. We have characterized genomic variation in thousands of ethnically and geographically diverse Africans in order to reconstruct human population history and local adaptation to variable environments and have identified candidate loci that play a role in alcohol metabolism and skin color. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Education] [Show ID: 38304]

As humans have evolved, so has our ability to drastically alter the planet we call home. In this collection of talks from the CARTA symposium, "Humans: The Planet-Altering Apes" you will learn about specific examples on how humans have changed Earth and what can be done to prevent its cataclysmic demise. David Holway addresses the challenges of emerging invasive species in our ecosystem. Oliver Ryder discusses the accelerated rate of loss of species due to human activities. Patricia Hunt talks about how human made chemicals and pollutants are impacting global fertility rates. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 38207]

As humans have evolved, so has our ability to drastically alter the planet we call home. In this collection of talks from the CARTA symposium, "Humans: The Planet-Altering Apes" you will learn about specific examples on how humans have changed Earth and what can be done to prevent its cataclysmic demise. David Holway addresses the challenges of emerging invasive species in our ecosystem. Oliver Ryder discusses the accelerated rate of loss of species due to human activities. Patricia Hunt talks about how human made chemicals and pollutants are impacting global fertility rates. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 38207]

As humans have evolved, so has our ability to drastically alter the planet we call home. In this collection of talks from the CARTA symposium, "Humans: The Planet-Altering Apes" you will learn about specific examples on how humans have changed Earth and what can be done to prevent its cataclysmic demise. David Holway addresses the challenges of emerging invasive species in our ecosystem. Oliver Ryder discusses the accelerated rate of loss of species due to human activities. Patricia Hunt talks about how human made chemicals and pollutants are impacting global fertility rates. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 38207]

As humans have evolved, so has our ability to drastically alter the planet we call home. In this collection of talks from the CARTA symposium, "Humans: The Planet-Altering Apes" you will learn about specific examples on how humans have changed Earth and what can be done to prevent its cataclysmic demise. David Holway addresses the challenges of emerging invasive species in our ecosystem. Oliver Ryder discusses the accelerated rate of loss of species due to human activities. Patricia Hunt talks about how human made chemicals and pollutants are impacting global fertility rates. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 38207]

As humans have evolved, so has our ability to drastically alter the planet we call home. In this collection of talks from the CARTA symposium, "Humans: The Planet-Altering Apes" you will learn about specific examples on how humans have changed Earth and what can be done to prevent its cataclysmic demise. David Holway addresses the challenges of emerging invasive species in our ecosystem. Oliver Ryder discusses the accelerated rate of loss of species due to human activities. Patricia Hunt talks about how human made chemicals and pollutants are impacting global fertility rates. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 38207]

As humans have evolved, so has our ability to drastically alter the planet we call home. In this collection of talks from the CARTA symposium, "Humans: The Planet-Altering Apes" you will learn about specific examples on how humans have changed Earth and what can be done to prevent its cataclysmic demise. David Holway addresses the challenges of emerging invasive species in our ecosystem. Oliver Ryder discusses the accelerated rate of loss of species due to human activities. Patricia Hunt talks about how human made chemicals and pollutants are impacting global fertility rates. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 38207]

As humans have evolved, so has our ability to drastically alter the planet we call home. In this collection of talks from the CARTA symposium, "Humans: The Planet-Altering Apes" you will learn about specific examples on how humans have changed Earth and what can be done to prevent its cataclysmic demise. David Holway addresses the challenges of emerging invasive species in our ecosystem. Oliver Ryder discusses the accelerated rate of loss of species due to human activities. Patricia Hunt talks about how human made chemicals and pollutants are impacting global fertility rates. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 38207]

We are experiencing an accelerated rate of loss of species due to human activities. This anthropogenic phenomenon extends beyond extinction. It encompasses an expanded loss of biodiversity as the genetic diversity of species diminish, reducing gene pools to “gene puddles.” We know details of species extinctions events from the fossil record, historical record, and from ancient DNA studies, and that historical processes shape extinction risk. Habitat loss and changing eco-environmental conditions, competition, and other factors produce genomic impacts, also influencing extinction risk. The legacy of past events impacts resiliency of species in the current environment in interpretable ways. Demographic trajectories reveal vulnerability to extinction. Remarkable advances in genomics technologies portend a deeper understanding of the evolution of life and the vulnerability of extant species to changes now taking place through human agency. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 37906]

We are experiencing an accelerated rate of loss of species due to human activities. This anthropogenic phenomenon extends beyond extinction. It encompasses an expanded loss of biodiversity as the genetic diversity of species diminish, reducing gene pools to “gene puddles.” We know details of species extinctions events from the fossil record, historical record, and from ancient DNA studies, and that historical processes shape extinction risk. Habitat loss and changing eco-environmental conditions, competition, and other factors produce genomic impacts, also influencing extinction risk. The legacy of past events impacts resiliency of species in the current environment in interpretable ways. Demographic trajectories reveal vulnerability to extinction. Remarkable advances in genomics technologies portend a deeper understanding of the evolution of life and the vulnerability of extant species to changes now taking place through human agency. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 37906]

We are experiencing an accelerated rate of loss of species due to human activities. This anthropogenic phenomenon extends beyond extinction. It encompasses an expanded loss of biodiversity as the genetic diversity of species diminish, reducing gene pools to “gene puddles.” We know details of species extinctions events from the fossil record, historical record, and from ancient DNA studies, and that historical processes shape extinction risk. Habitat loss and changing eco-environmental conditions, competition, and other factors produce genomic impacts, also influencing extinction risk. The legacy of past events impacts resiliency of species in the current environment in interpretable ways. Demographic trajectories reveal vulnerability to extinction. Remarkable advances in genomics technologies portend a deeper understanding of the evolution of life and the vulnerability of extant species to changes now taking place through human agency. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 37906]

We are experiencing an accelerated rate of loss of species due to human activities. This anthropogenic phenomenon extends beyond extinction. It encompasses an expanded loss of biodiversity as the genetic diversity of species diminish, reducing gene pools to “gene puddles.” We know details of species extinctions events from the fossil record, historical record, and from ancient DNA studies, and that historical processes shape extinction risk. Habitat loss and changing eco-environmental conditions, competition, and other factors produce genomic impacts, also influencing extinction risk. The legacy of past events impacts resiliency of species in the current environment in interpretable ways. Demographic trajectories reveal vulnerability to extinction. Remarkable advances in genomics technologies portend a deeper understanding of the evolution of life and the vulnerability of extant species to changes now taking place through human agency. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 37906]

We are experiencing an accelerated rate of loss of species due to human activities. This anthropogenic phenomenon extends beyond extinction. It encompasses an expanded loss of biodiversity as the genetic diversity of species diminish, reducing gene pools to “gene puddles.” We know details of species extinctions events from the fossil record, historical record, and from ancient DNA studies, and that historical processes shape extinction risk. Habitat loss and changing eco-environmental conditions, competition, and other factors produce genomic impacts, also influencing extinction risk. The legacy of past events impacts resiliency of species in the current environment in interpretable ways. Demographic trajectories reveal vulnerability to extinction. Remarkable advances in genomics technologies portend a deeper understanding of the evolution of life and the vulnerability of extant species to changes now taking place through human agency. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 37906]

We are experiencing an accelerated rate of loss of species due to human activities. This anthropogenic phenomenon extends beyond extinction. It encompasses an expanded loss of biodiversity as the genetic diversity of species diminish, reducing gene pools to “gene puddles.” We know details of species extinctions events from the fossil record, historical record, and from ancient DNA studies, and that historical processes shape extinction risk. Habitat loss and changing eco-environmental conditions, competition, and other factors produce genomic impacts, also influencing extinction risk. The legacy of past events impacts resiliency of species in the current environment in interpretable ways. Demographic trajectories reveal vulnerability to extinction. Remarkable advances in genomics technologies portend a deeper understanding of the evolution of life and the vulnerability of extant species to changes now taking place through human agency. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 37906]

We are experiencing an accelerated rate of loss of species due to human activities. This anthropogenic phenomenon extends beyond extinction. It encompasses an expanded loss of biodiversity as the genetic diversity of species diminish, reducing gene pools to “gene puddles.” We know details of species extinctions events from the fossil record, historical record, and from ancient DNA studies, and that historical processes shape extinction risk. Habitat loss and changing eco-environmental conditions, competition, and other factors produce genomic impacts, also influencing extinction risk. The legacy of past events impacts resiliency of species in the current environment in interpretable ways. Demographic trajectories reveal vulnerability to extinction. Remarkable advances in genomics technologies portend a deeper understanding of the evolution of life and the vulnerability of extant species to changes now taking place through human agency. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 37906]

We are experiencing an accelerated rate of loss of species due to human activities. This anthropogenic phenomenon extends beyond extinction. It encompasses an expanded loss of biodiversity as the genetic diversity of species diminish, reducing gene pools to “gene puddles.” We know details of species extinctions events from the fossil record, historical record, and from ancient DNA studies, and that historical processes shape extinction risk. Habitat loss and changing eco-environmental conditions, competition, and other factors produce genomic impacts, also influencing extinction risk. The legacy of past events impacts resiliency of species in the current environment in interpretable ways. Demographic trajectories reveal vulnerability to extinction. Remarkable advances in genomics technologies portend a deeper understanding of the evolution of life and the vulnerability of extant species to changes now taking place through human agency. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 37906]

We are experiencing an accelerated rate of loss of species due to human activities. This anthropogenic phenomenon extends beyond extinction. It encompasses an expanded loss of biodiversity as the genetic diversity of species diminish, reducing gene pools to “gene puddles.” We know details of species extinctions events from the fossil record, historical record, and from ancient DNA studies, and that historical processes shape extinction risk. Habitat loss and changing eco-environmental conditions, competition, and other factors produce genomic impacts, also influencing extinction risk. The legacy of past events impacts resiliency of species in the current environment in interpretable ways. Demographic trajectories reveal vulnerability to extinction. Remarkable advances in genomics technologies portend a deeper understanding of the evolution of life and the vulnerability of extant species to changes now taking place through human agency. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 37906]

Huberman Lab Podcast Notes Key Takeaways Neural circuits (not individual brain areas) trigger aggressionAggression is not a switch, it's a process with a beginning, middle, and endAggression actually hinges on the hormone estrogenTestosterone in and of itself does not trigger aggression – testosterone aromatized into estrogen within the brain and binding to estrogen receptors in area of the brain that leads to aggressionEstrogen triggers aggression in brain and testosterone increases the pressure toward an aggressive episodeRecipe for aggression & reactivity: increased cortisol, reduced serotonin, short daysSelf-regulation is a key component of whether someone will engage in aggressive behaviorTools to reduce aggressive tendencies and impulsivity: pay attention to how daylight changes makes you feel, supplement with omega-3, supplement with ashwagandha in 2 week on/2week off cycles, get sunlight early in the day, try a hot bath or sauna, avoid beverages that contain both alcohol and caffeineRead the full notes @ podcastnotes.orgThis episode I describe the neural mechanisms that activate and control aggressive states and beahviors and the role of hormones—estrogen and testosterone—in mediating violent and and/or competive aggression. I also describe tools that can be used to modulate the factors that have been shown to ‘prime' an individual for aggression, including sunlight, estrogen sensitivity, competition within social settings, and overall stress levels, and the hormone cortisol. I discuss how substances such as caffeine and alcohol can impact impulsive behaviors, and how nutrition and supplementation can be used to regulate mood and aggression.  Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman ROKA: https://www.roka.com -- code: huberman Helix Sleep: https://www.helixsleep.com/huberman See Andrew Huberman Live: The Brain Body Contract https://hubermanlab.com/tour Our Patreon page https://www.patreon.com/andrewhuberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Aggression, Types of Aggression (00:03:33) AG1 (Athletic Greens), ROKA, Helix Sleep (00:08:29) Neural Circuits for Aggression, “Hydraulic Pressure Model”  (00:15:50) Brain Regions Controlling Aggression, Ventromedial Hypothalamus (VMH)  (00:22:14) Psychiatric Disorders & Aggression  (00:23:36) Stimulation of the VMH, Estrogen Receptors & Aggression (00:31:57) Neural Circuits Mediating Physical Acts of Aggression, Biting (0:35:56) Testosterone & Competitiveness/Estrogen & Aggression  (00:43:00) Sunlight, Melatonin & Aggression  (00:45:46) Cortisol, Serotonin & Aggressive Behaviors  (00:51:56) Tool: Omega-3 Supplementation & Mood  (00:54:18) Tool: Sunlight, Sauna & Cortisol Reduction (00:55:54) Tool: Ashwagandha & Cortisol Reduction (00:57:06) Tool: Seasonality/Sunlight, Genetic Variation in Estrogen Sensitivity (01:00:37) Testosterone & Aggression, Competitive Work Environments (01:05:07) Testosterone, Amygdala, Challenge & Effort  (01:09:27) Caffeine, Alcohol & Impulsivity  (01:13:15) Tool: Caffeinated Alcohol Beverages, Impulsivity & Aggression  (01:17:18) Tool: ADHD, Acetyl-L Carnitine & Aggressive Behavior  (01:24:10) Factors Affecting the “Hydraulic Pressure Model” of Aggression  (01:25:44) Book by Dr. David Anderson, Aggression & Social Relationships  (01:27:35) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Patreon, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter Title Card Photo Credit: Mike Blabac Disclaimer

This episode I describe the neural mechanisms that activate and control aggressive states and beahviors and the role of hormones—estrogen and testosterone—in mediating violent and and/or competive aggression. I also describe tools that can be used to modulate the factors that have been shown to ‘prime' an individual for aggression, including sunlight, estrogen sensitivity, competition within social settings, and overall stress levels, and the hormone cortisol. I discuss how substances such as caffeine and alcohol can impact impulsive behaviors, and how nutrition and supplementation can be used to regulate mood and aggression.  Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman ROKA: https://www.roka.com -- code: huberman Helix Sleep: https://www.helixsleep.com/huberman See Andrew Huberman Live: The Brain Body Contract https://hubermanlab.com/tour Our Patreon page https://www.patreon.com/andrewhuberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Aggression, Types of Aggression (00:03:33) AG1 (Athletic Greens), ROKA, Helix Sleep (00:08:29) Neural Circuits for Aggression, “Hydraulic Pressure Model”  (00:15:50) Brain Regions Controlling Aggression, Ventromedial Hypothalamus (VMH)  (00:22:14) Psychiatric Disorders & Aggression  (00:23:36) Stimulation of the VMH, Estrogen Receptors & Aggression (00:31:57) Neural Circuits Mediating Physical Acts of Aggression, Biting (0:35:56) Testosterone & Competitiveness/Estrogen & Aggression  (00:43:00) Sunlight, Melatonin & Aggression  (00:45:46) Cortisol, Serotonin & Aggressive Behaviors  (00:51:56) Tool: Omega-3 Supplementation & Mood  (00:54:18) Tool: Sunlight, Sauna & Cortisol Reduction (00:55:54) Tool: Ashwagandha & Cortisol Reduction (00:57:06) Tool: Seasonality/Sunlight, Genetic Variation in Estrogen Sensitivity (01:00:37) Testosterone & Aggression, Competitive Work Environments (01:05:07) Testosterone, Amygdala, Challenge & Effort  (01:09:27) Caffeine, Alcohol & Impulsivity  (01:13:15) Tool: Caffeinated Alcohol Beverages, Impulsivity & Aggression  (01:17:18) Tool: ADHD, Acetyl-L Carnitine & Aggressive Behavior  (01:24:10) Factors Affecting the “Hydraulic Pressure Model” of Aggression  (01:25:44) Book by Dr. David Anderson, Aggression & Social Relationships  (01:27:35) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Patreon, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter Title Card Photo Credit: Mike Blabac Disclaimer