Podcasts about Geschwind

  • 59PODCASTS
  • 79EPISODES
  • 39mAVG DURATION
  • ?INFREQUENT EPISODES
  • Mar 13, 2025LATEST

POPULARITY

20172018201920202021202220232024


Best podcasts about Geschwind

Latest podcast episodes about Geschwind

Brain & Life
Finding Joy with Parent and Autism Advocate Tola Andu

Brain & Life

Play Episode Listen Later Mar 13, 2025 69:13


In this episode of the Brain & Life Podcast, co-host Dr. Daniel Correa is joined by Tola Andu, an autism advocate and content creator who shares her journey raising her 19-year-old son Kevin on social media under the handle @RaisingKevin_. Her platform sheds light on autism and offers a joyful perspective on raising a neurodivergent child. Tola discusses her passion for changing the narrative surrounding autism and advocating for acceptance and understanding, especially within the Nigerian community. Dr. Correa is then joined by Dr. Dan Geschwind, a professor and academic and research leader at the UCLA, and one of the world's leading experts on autism who guided development of the Autism Genetic Resources Exchange alongside Cure Autism Now, currently run by Autism Speaks. Dr. Geschwind explains risk factors, diagnostic processes, and what research is being done in the autism community.   Additional Resources Raising Kevin What is Autism Spectrum Disorder? What Does Neurodivergent Mean? A Theater Group That Features Neurodiversity on the Stage Other Brain & Life Podcast Episodes From Adolescence to Adulthood: Exploring Autism with Abbey and Christine Romeo ‘Bake Off' Star Lizzie Acker on Showstopping Cakes through Neurodivergent Eyes   We want to hear from you! Have a question or want to hear a topic featured on the Brain & Life Podcast? ·       Record a voicemail at 612-928-6206 ·       Email us at BLpodcast@brainandlife.org   Social Media: Tola Andu @RaisingKevin_; Dr. Dan Geschwind @uclacart Hosts: Dr. Daniel Correa @neurodrcorrea; Dr. Katy Peters @KatyPetersMDPhD

Devils in the Details
#80: Special– The Double Signing of Matthijs de Ligt and Noussair Mazraoui (with Marc Geschwind)

Devils in the Details

Play Episode Listen Later Aug 14, 2024 69:12


Today, we welcome Marc Geschwind (@MarcGeschwind) to discuss Matthijs de Ligt and Noussair Mazraoui, travelling all the way from their time as youngsters at Ajax to their journeys at superclubs over the last few seasons. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Hi, Baby! Der Mama-Podcast
Autismus und ADHS – Unser Weg zur Doppeldiagnose

Hi, Baby! Der Mama-Podcast

Play Episode Listen Later Jul 14, 2024 65:13


Seit Kurzem hat unser sechsjähriger Sohn die Doppeldiagnose Autismus und ADHS. Wie kamen wir zur Diagnose ADHS? Was waren typische Anzeichen für uns als Eltern, die den Verdacht aufbrachten, dass unser Sohn auch ADHS hat? Wie lief die Diagnose für ADHS generell ab? Und wie geht es uns jetzt, mit dieser Doppeldiagnose. Was ändert sich dadurch, für unseren Sohn, aber auch für uns als Familie? Und: ich spreche in dieser Folge auch offen und ehrlich über das meiner Meinung nach sehr wichtige Thema ADHS und Medikamente für Kinder, das von zu vielen Menschen aus Angst vor zu viel Gegenwind totgeschwiegen wird. *Über die Erstdiagnose Autismus gibt es eine eigene Podcast-Folge "Unser Sohn ist Autist", die im März 2023 erschien und die ihr hier hören könnt *Rabattcodes und Infos zu Werbepartnern findest Du hier: https://linktr.ee/hibabypodcastQuellen zu Zahlen und Fakten in dieser Folge: https://publications.aap.org/pediatrics/article/151/2/e2022056594/190525/Prevalence-and-Disparities-in-the-Detection-of?autologincheck=redirected McKechnie DGJ, O'Nions E, Dunsmuir S, Petersen I. Attention-deficit hyperactivity disorder diagnoses and prescriptions in UK primary care, 2000-2018: population-based cohort study. BJPsych Open. 2023 Jul 17;9(4):e121. doi: 10.1192/bjo.2023.512.Bachmann, Christian J.; Philipsen, Alexandra; Hoffmann, Falk. ADHS in Deutschland: Trends in Diagnose und medikamentöser Therapie. Bundesweite Auswertung von Krankenkassendaten der Jahre 2009–2014 zur Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS) bei Kindern, Jugendlichen und Erwachsenen. Dtsch Arztebl Int 2017; 114: 141-8; DOI: 10.3238/arztebl.2017.0141 Ramaswami & Geschwind (2018) „Genetics of autism spectrum disorder“ Sandin (2017) „the heritability of autism spectrum disorder“#autismus #adhs #neurodivergenz #neurodivergentekinder #autismusfamilien #lebenmitautismusundadhs #mamapodcast #neurodivergentesfamilienleben Hosted on Acast. See acast.com/privacy for more information.

trashaLISTic - Der Reality-TV Podcast auf Couch Island
Kampf der Realitystars - Folge 06: Sie reiten geschwind, auf Amadeus und Sabrina

trashaLISTic - Der Reality-TV Podcast auf Couch Island

Play Episode Listen Later May 22, 2024 36:58


Eine Folge voller authentischer Momente: Der Fakeste im Format wird einfach durch einen Pferdekopf ersetzt, in Calvins Bauchtasche ist kein Delfin und Lilo sieht den großen Streit nicht hervor. Lasst uns lieber über die schönen Momente sprechen, z.B. über Maurice' Studiengang. Schaut auch bei Insta rein: https://www.instagram.com/trashalistic/

Under Pleasure
#59 Beyond "toxic" masculinity! So findest du deinen wahren sexuellen Ausdruck - mit Sex-Coach Lukas Geschwind

Under Pleasure

Play Episode Listen Later Mar 1, 2024 47:28


In dieser Podcastfolge spreche ich mit Lukas Geschwind über Bilder und Konditionierungen, die Männlichkeit umgeben. Wir erläutern, was es mit toxischer Männlichkeit auf sich hat und wie du aus erlernten Mustern ausbrechen kannst, um deinen ganz eigenen wahren sexuellen Ausdruck zu finden. Lukas ist sexological Bodyworker und somatischer Coach für Intimität und Sexualität. Er versteht sich als queerer Cis-Mann. Du erfährst: wann Geschlechterrollen dein Erleben von Sexualität einschränken wie du Ausprägungen von toxischer Männlichkeit begegnen kannst wie du mehr für deine sexuellen Bedürfnisse einstehen und sorgen kannst welche Räume es braucht, wenn du deinen wahren sexuellen Ausdruck finden möchtest Infos zu Lukas: Lukas' Website Workshop “Liebe, Sex und Männlichkeiten” Zu Christins Website: ⁠https://christinchudy.com⁠ Zu Christins Instagram: ⁠https://www.instagram.com/christinchudy/

Slovakia Today, English Language Current Affairs Programme from Slovak Radio
Tracing rose breeder Rudolf Geschwind (29.2.2024 16:00)

Slovakia Today, English Language Current Affairs Programme from Slovak Radio

Play Episode Listen Later Feb 29, 2024 23:48


Paying tribute to the last rose breeder in Slovakia who passed away on Saturday, 24 February 2024, we get back to the series tracing the work of internationally acclaimed 19th century rose breeder Rudolf Geschwind. As he was a great role model for Szilvester Gyory, we will present to you some of Geschwind's rose varieties that have been popular in Norh America, Iceland, Scandinavian countries as well as South Africa and New Zealand up until today. Featuring Jana Salatova, garden designer, Ivana Sarvasova and Vladimir Jezovic, Arboretum Borová hora, Peter Hoťka, Arboretum Mlyňany - Slovak Academy of Sciences, Charles Quest-Ritson, historian and author of RHS Encyclopedia of roses and Erich Unmuth, Rosenkultivarium Baden.

Slovakia Today, English Language Current Affairs Programme from Slovak Radio
Slovakia Today, English Language Current Affairs Programme from Slovak Radio (29.2.2024 16:00)

Slovakia Today, English Language Current Affairs Programme from Slovak Radio

Play Episode Listen Later Feb 29, 2024


Paying tribute to the last rose breeder in Slovakia who passed away on Saturday, 24 February 2024, we get back to the series tracing the work of internationally acclaimed 19th century rose breeder Rudolf Geschwind. As he was a great role model for Szilvester Gyory, we will present to you some of Geschwind's rose varieties that have been popular in Norh America, Iceland, Scandinavian countries as well as South Africa and New Zealand up until today. Featuring Jana Salatova, garden designer, Ivana Sarvasova and Vladimir Jezovic, Arboretum Borová hora, Peter Hoťka, Arboretum Mlyňany - Slovak Academy of Sciences, Charles Quest-Ritson, historian and author of RHS Encyclopedia of roses and Erich Unmuth, Rosenkultivarium Baden.

The Jayme & Grayson Podcast
Eric Geschwind of Pinnacle Bank is here to help support Coats for Kids - HR1

The Jayme & Grayson Podcast

Play Episode Listen Later Dec 1, 2023 39:09


Zwischenwasser
#144 Zwischen Kröger und Kristmas

Zwischenwasser

Play Episode Listen Later Nov 27, 2023 21:32


Die voradventliche Zeit mit ihren kurzen dunklen Tagen, lädt zum Verweilen und der Beschäftigung mit den wichtigen Fragen, Kann die Butter an den Rand, ist Chad Kröger wirklich ein Musikant? Keine Angst wir werden es dir sagen, und damit du auch in Zukunft nicht musst verzagen, brauchen für die nächsten Folgen deine Fragen Beantworten werden wir auch diese Geschwind, und mit den tollen Spendenaktionen aus deiner Nähe helfen wir jedem Kind. Zwischenwasser-Podcast-Playlist: http://bit.ly/ZwiwaPlaylist Du willst Teil der ZWIWA-Community werden? Folgen, Teilen und mit uns in Kontakt treten! Zwischenwasser auf Instagram: http://bit.ly/ZwiwaInsta

Die Märchentante - Dein Einschlafpodcast
Geschwind, wie der Wind

Die Märchentante - Dein Einschlafpodcast

Play Episode Listen Later Nov 26, 2023 28:07


✨NEU: Unser EINSCHLAF-ADVENTSKALENDER ✨Jeden Tag ab 20 Uhr - eine neue Einschlaf-Folge auf unserem YouTube-KanalDIREKT-LINKFolge 141: GESCHWIND, WIE DER WINDIn dieser Folge wartet eine entspannende Abendroutine / Meditation und ein Märchen aus TIROL zum Einschlafen auf Dich. Es ist ein klassisches Märchen mit einem König, einer Prinzessin einen Drachen - und natürlich mit einem Helden. Und der Held dieser Geschichte heißt Max.Max erbt drei ganz besondere Hunde von seinem Vater und nimmt es mit einem gefährlichen Drachen auf, um die Königstochter zu retten - ob es ihm wohl gelingt?Gerne verrate ich Dir: Auch dieses Märchen wird gut ausgehen, sodass Du jederzeit einfach einschlafen kannst.

Science (Video)
Autism: The Human Brain on a Continuum with Daniel Geschwind - Autism Tree Project Foundation Global Neurodiversity Conference 2023

Science (Video)

Play Episode Listen Later Nov 22, 2023 33:10


Daniel Geschwind, M.D., Ph.D., explains autism's genetic roots using a polygenic model, where multiple genes, including common variations, contribute to the risk. Geschwind stresses a continuum in social behavior, showcasing features like synesthesia and exceptional talents as part of human variation. Geschwind,emphasizes the complexity of autism, urging recognition of strengths and vulnerabilities in the spectrum of human cognition and behavior. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39166]

Health and Medicine (Video)
Autism: The Human Brain on a Continuum with Daniel Geschwind - Autism Tree Project Foundation Global Neurodiversity Conference 2023

Health and Medicine (Video)

Play Episode Listen Later Nov 22, 2023 33:10


Daniel Geschwind, M.D., Ph.D., explains autism's genetic roots using a polygenic model, where multiple genes, including common variations, contribute to the risk. Geschwind stresses a continuum in social behavior, showcasing features like synesthesia and exceptional talents as part of human variation. Geschwind,emphasizes the complexity of autism, urging recognition of strengths and vulnerabilities in the spectrum of human cognition and behavior. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39166]

Autism (Audio)
Autism: The Human Brain on a Continuum with Daniel Geschwind - Autism Tree Project Foundation Global Neurodiversity Conference 2023

Autism (Audio)

Play Episode Listen Later Nov 22, 2023 33:10


Daniel Geschwind, M.D., Ph.D., explains autism's genetic roots using a polygenic model, where multiple genes, including common variations, contribute to the risk. Geschwind stresses a continuum in social behavior, showcasing features like synesthesia and exceptional talents as part of human variation. Geschwind,emphasizes the complexity of autism, urging recognition of strengths and vulnerabilities in the spectrum of human cognition and behavior. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39166]

University of California Audio Podcasts (Audio)
Autism: The Human Brain on a Continuum with Daniel Geschwind - Autism Tree Project Foundation Global Neurodiversity Conference 2023

University of California Audio Podcasts (Audio)

Play Episode Listen Later Nov 22, 2023 33:10


Daniel Geschwind, M.D., Ph.D., explains autism's genetic roots using a polygenic model, where multiple genes, including common variations, contribute to the risk. Geschwind stresses a continuum in social behavior, showcasing features like synesthesia and exceptional talents as part of human variation. Geschwind,emphasizes the complexity of autism, urging recognition of strengths and vulnerabilities in the spectrum of human cognition and behavior. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39166]

Health and Medicine (Audio)
Autism: The Human Brain on a Continuum with Daniel Geschwind - Autism Tree Project Foundation Global Neurodiversity Conference 2023

Health and Medicine (Audio)

Play Episode Listen Later Nov 22, 2023 33:10


Daniel Geschwind, M.D., Ph.D., explains autism's genetic roots using a polygenic model, where multiple genes, including common variations, contribute to the risk. Geschwind stresses a continuum in social behavior, showcasing features like synesthesia and exceptional talents as part of human variation. Geschwind,emphasizes the complexity of autism, urging recognition of strengths and vulnerabilities in the spectrum of human cognition and behavior. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39166]

Science (Audio)
Autism: The Human Brain on a Continuum with Daniel Geschwind - Autism Tree Project Foundation Global Neurodiversity Conference 2023

Science (Audio)

Play Episode Listen Later Nov 22, 2023 33:10


Daniel Geschwind, M.D., Ph.D., explains autism's genetic roots using a polygenic model, where multiple genes, including common variations, contribute to the risk. Geschwind stresses a continuum in social behavior, showcasing features like synesthesia and exceptional talents as part of human variation. Geschwind,emphasizes the complexity of autism, urging recognition of strengths and vulnerabilities in the spectrum of human cognition and behavior. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39166]

UC San Diego (Audio)
Autism: The Human Brain on a Continuum with Daniel Geschwind - Autism Tree Project Foundation Global Neurodiversity Conference 2023

UC San Diego (Audio)

Play Episode Listen Later Nov 22, 2023 33:10


Daniel Geschwind, M.D., Ph.D., explains autism's genetic roots using a polygenic model, where multiple genes, including common variations, contribute to the risk. Geschwind stresses a continuum in social behavior, showcasing features like synesthesia and exceptional talents as part of human variation. Geschwind,emphasizes the complexity of autism, urging recognition of strengths and vulnerabilities in the spectrum of human cognition and behavior. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39166]

Hemispherics
#62: Los savants: lo que el cerebro es capaz de hacer

Hemispherics

Play Episode Listen Later Aug 12, 2023 64:03


En el episodio de hoy, hablo de un tema que se escapa un poco de la temática habitual del podcast. Este episodio es una “curiosidad de la neurociencia”; una indagación en un tema que desde hace muchos años me ha llamado la atención. Se trata de los savants. Los savants son personas que bien porque han nacido con problemas en el desarrollo o por una lesión cerebral adquirida, son capaces de tener habilidades extraordinarias. Parece ser que la mitad de los savant son autistas, uno de cada diez autistas es savant y uno de cada mil individuos que tienen dañado el cerebro o padecen retraso mental. Son personas que, sin necesidad de entrenamiento, aprendizaje o interés previo, tienen unas habilidades increíbles, sobre todo en el campo de la música, el cálculo o el dibujo. Referencias del episodio: 1. Treffert D. A. (2014). Savant syndrome: realities, myths and misconceptions. Journal of autism and developmental disorders, 44(3), 564–571. (https://pubmed.ncbi.nlm.nih.gov/23918440/). 2. Treffert DA. The savant syndrome: an extraordinary condition. A synopsis: past, present, future. Philos Trans R Soc Lond B Biol Sci. 2009 May 27;364(1522):1351-7 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677584/). 3. Barr MW. Some notes on echolalia, with the report of an extraordinary case. J Nerv Ment Dis 1898;25:20-30 (https://zenodo.org/record/1734113). 4. Mishkin M, Malamut B, Bachevalier J. Memories and habits: two neural systems. In: Lynch G, McGaugh JL, Weinberger NM, editors. Neurobiology of learning and memory. New York: Guilford Press;1984. p.65-77. 5. Kapur N. (1996). Paradoxical functional facilitation in brain-behaviour research. A critical review. Brain : a journal of neurology, 119 ( Pt 5), 1775–1790.https://doi.org/10.1093/brain/119.5.1775 (https://pubmed.ncbi.nlm.nih.gov/9236635/). 6. Boso, M., Emanuele, E., Prestori, F., Politi, P., Barale, F., & D'Angelo, E. (2010). Autism and genius: is there a link? The involvement of central brain loops and hypotheses for functional testing. Functional neurology, 25(1), 15–20 (https://pubmed.ncbi.nlm.nih.gov/20630121/). 7. Snyder, A. W., Mulcahy, E., Taylor, J. L., Mitchell, D. J., Sachdev, P., & Gandevia, S. C. (2003). Savant-like skills exposed in normal people by suppressing the left fronto-temporal lobe. Journal of integrative neuroscience, 2(2), 149–158. https://doi.org/10.1142/s0219635203000287 (https://pubmed.ncbi.nlm.nih.gov/15011267/). 8. Snyder, A. W., & Thomas, M. (1997). Autistic artists give clues to cognition. Perception, 26(1), 93–96. https://doi.org/10.1068/p260093 (https://pubmed.ncbi.nlm.nih.gov/9196693/). 9. Humphrey, N. (1998). Cave Art, Autism, and the Evolution of the Human Mind. Cambridge Archaeological Journal, 8(2), 165-191. doi:10.1017/S0959774300001827 (https://www.cambridge.org/core/journals/cambridge-archaeological-journal/article/abs/cave-art-autism-and-the-evolution-of-the-human-mind/7E969D1ACAB536BD809348B9B4FE5C4D#). 10. Spikins, P., Scott, C. & Wright, B. (2018). How Do We Explain ‛Autistic Traits' in European Upper Palaeolithic Art?. Open Archaeology, 4(1), 262-279. https://doi.org/10.1515/opar-2018-0016 (https://www.degruyter.com/document/doi/10.1515/opar-2018-0016/html#APA). 11. Folgerø, P. O., Johansson, C., & Stokkedal, L. H. (2021). The Superior Visual Perception Hypothesis: Neuroaesthetics of Cave Art. Behavioral sciences (Basel, Switzerland), 11(6), 81. https://doi.org/10.3390/bs11060081 (https://pubmed.ncbi.nlm.nih.gov/34073168/). 12. Lai G, Pantazatos SP, Schneider H, Hirsch J. Neural systems for speech and song in autism. Brain. 2012 Mar;135(Pt 3):961-75. doi: 10.1093/brain/awr335. Epub 2012 Feb 1. PMID: 22298195; PMCID: PMC3286324 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286324/). 13. Beate H. A memoir of the savant syndrome. Bright splinters of the mind: a personal story of research with autistics savant. London: Jessica Kingsley Publishers; 2001. p. 160 (https://www.proquest.com/docview/198983834). 14. Muñoz-Yunta JA , Ortiz T, Amo C, Fernández-Lucas A, Maestú F, Palau-Baduell M. El síndrome de savant o idiot savant. Rev Neurol 2003;36 (S1):157-0 (https://neurologia.com/articulo/2003061). 15. Geschwind, N., & Galaburda, A. M. (1985). Cerebral lateralization. Biological mechanisms, associations, and pathology: I. A hypothesis and a program for research. Archives of neurology, 42(5), 428–459. https://doi.org/10.1001/archneur.1985.04060050026008 (https://pubmed.ncbi.nlm.nih.gov/3994562/). 16. Navarro-Pardo E, Alonso-Esteban Y, Alcantud-Marin F, Murphy M. Do Savant Syndrome and Autism Spectrum Disorders Share Sex Differences? A Comprehensive Review. Soa Chongsonyon Chongsin Uihak. 2023 Apr 1;34(2):117-124. doi: 10.5765/jkacap.230008. PMID: 37035793; PMCID: PMC10080262 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080262/). 17. Pring, L., Ryder, N., Crane, L., & Hermelin, B. (2010). Local and global processing in savant artists with autism. Perception, 39(8), 1094–1103. https://doi.org/10.1068/p6674 (https://pubmed.ncbi.nlm.nih.gov/20942360/). 18. Mottron L, Dawson M, Soulières I. Enhanced perception in savant syndrome: patterns, structure and creativity. Philos Trans R Soc Lond B Biol Sci. 2009 May 27;364(1522):1385-91. doi: 10.1098/rstb.2008.0333. PMID: 19528021; PMCID: PMC2677591 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677591/). 19. Park HO. Autism Spectrum Disorder and Savant Syndrome: A Systematic Literature Review. Soa Chongsonyon Chongsin Uihak. 2023 Apr 1;34(2):76-92. doi: 10.5765/jkacap.230003. PMID: 37035789; PMCID: PMC10080257 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080257/). 20. Treffert, D. A., & Treffert, D. A. (2021). The Sudden Savant: A New Form of Extraordinary Abilities. WMJ : official publication of the State Medical Society of Wisconsin, 120(1), 69–73 (https://pubmed.ncbi.nlm.nih.gov/33974770/). 21. Documental “Mentes prodigiosas”. https://www.youtube.com/playlist?list=PL10391BEC6C746C6D 22. Daniel Tammet: sinestesia numérica. https://www.youtube.com/watch?v=HqBzez4WKuU&ab_channel=nuecesyneuronas 23. Documental sobre savant en Discovery: https://www.youtube.com/watch?v=BhZTM-aB0lw&t=2290s&ab_channel=PROYECTOTHERAPI 24. Accidental Genius | Darold Treffert | TEDxFondduLac : https://www.youtube.com/watch?v=Wxe1PkyJev8&ab_channel=TEDxTalks

The Jayme & Grayson Podcast
Eric Geschwind of Pinnacle Bank joins us to talk Operation Breakthrough - HR1

The Jayme & Grayson Podcast

Play Episode Listen Later Aug 9, 2023 38:24


Slovakia Today, English Language Current Affairs Programme from Slovak Radio
RERUN: Tracing Rudolf Geschwind - Diaries (27.7.2023 16:00)

Slovakia Today, English Language Current Affairs Programme from Slovak Radio

Play Episode Listen Later Jul 27, 2023 31:08


RERUN: Following the news bulletin we will continue in the series about the rose breeder Rudolf Geschwind. In the 5th part, we trace the mystery of the now world famous rose breeder's lost diaries. Are they in Slovakia?

Devils in the Details
#43: Mason Mount and Andre Onana Deep Dive (with Orlando Valman and Marc Geschwind)

Devils in the Details

Play Episode Listen Later Jul 24, 2023 72:11


Two great new signings, two great guests to give us the best info. We first welcomed Orlando Valman (@0rland1nh0) to give us the lowdown on Mason Mount's career to date, after which Marc Geschwind (@MarcGeschwind) spoke to us about Andre Onana's rise to fame at Ajax. You can find Orlando over at Scouted Football (@ScoutedFtbl) or The Chelsea Spot (@TheChelseaSpot) and Marc at EiF Soccer (@EiFSoccer).

PaperPlayer biorxiv neuroscience
Improved Protocol for Reproducible Human Cortical Organoids Reveals Early Alterations in Metabolism with MAPT Mutations

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Jul 11, 2023


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.11.548571v1?rss=1 Authors: Bertucci, T., Bowles, K. R., Lotz, S., Qi, L., Stevens, K., Goderie, S. K., Borden, S., Oja, L., Lane, K., Lotz, R., Lotz, H., Chowdhury, R., Joy, S., Arduini, B. L., Butler, D. C., Miller, M., Baron, H., Sandhof, C. A., Silva, M. C., Haggarty, S. J., Karch, C. M., Geschwind, D. H., Goate, A. M., Temple, S. Abstract: Cerebral cortical-enriched organoids derived from human pluripotent stem cells (hPSCs) are valuable models for studying neurodevelopment, disease mechanisms, and therapeutic development. However, recognized limitations include the high variability of organoids across hPSC donor lines and experimental replicates. We report a 96-slitwell method for efficient, scalable, reproducible cortical organoid production. When hPSCs were cultured with controlled-release FGF2 and an SB431542 concentration appropriate for their TGFBR1/ALK5 expression level, organoid cortical patterning and reproducibility were significantly improved. Well-patterned organoids included 16 neuronal and glial subtypes by single cell RNA sequencing (scRNA-seq), frequent neural progenitor rosettes and robust BCL11B+ and TBR1+ deep layer cortical neurons at 2 months by immunohistochemistry. In contrast, poorly-patterned organoids contain mesendoderm-related cells, identifiable by negative QC markers including COL1A2. Using this improved protocol, we demonstrate increased sensitivity to study the impact of different MAPT mutations from patients with frontotemporal dementia (FTD), revealing early changes in key metabolic pathways. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Was talkst du!
Leidet ihr auch an Tromsö?

Was talkst du!

Play Episode Listen Later Mar 22, 2023 60:45


Geschwind rollern wir verkatert dem Frühling entgehen. Aber Vorsicht: Wenn man die Kindern ans Steuer lässt, kann man schnell abstürzen. Lasst uns dabei eine kleine Pause machen und eine Brotzeit einlegen. Dabei erzählen wir euch von einer kleiner Insel im Meer, einem kleinen Aufruhr in England und vielleicht liest euch JP auch noch etwas vor. LG an alle!

Axess Podd
Förklara din forskning 2023 – Från förintelse till internering med Britta Zetterström Geschwind

Axess Podd

Play Episode Listen Later Mar 13, 2023 29:16


Britta Zetterström Geschwind har disputerat inom etnologi vid Stockholms universitet och är idag forskning-koordinator vid Sveriges museum om Förintelsen. Hon är aktuell med en studie av Gunnarpshemmet, ett interneringsläger för kvinnliga flyktingar i Sverige mellan 1945 och 1946. Varför låste man in kvinnor som nyss suttit i koncentrationsläger?

PaperPlayer biorxiv neuroscience
Transcriptional networks predating cognition-associated pyramidal lineages are restructured by erythropoietin

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Feb 5, 2023


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.02.04.527116v1?rss=1 Authors: Singh, M., Zhao, Y., Daguano Gastaldi, V., Wojcik, S. M., Curto, Y., Kawaguchi, R., Merino, R. M., Fernandez Garcia-Agudo, L., Taschenberger, H., Brose, N., Geschwind, D., Nave, K.-A., Ehrenreich, H. Abstract: Recombinant human erythropoietin (rhEPO) has potent procognitive effects,hematopoiesis-independent, but underlying mechanisms and physiological role of brain-expressed EPO have remained obscure. Here, we provide encyclopedic transcriptional hippocampal profiling of mice treated with rhEPO. Based on ~108,000 single nuclei, we unmask multiple pyramidal lineages with their comprehensive molecular signatures. By temporal profiling and gene regulatory analysis, we build a developmental trajectory of CA1 pyramidal neurons derived from multiple predecessor lineages and elucidate gene regulatory networks underlying their fate determination. With EPO as tool, we discover novel populations of newly differentiating pyramidal neurons, overpopulating to ~200% upon rhEPO with upregulation of genes crucial for neurodifferentiation, dendrite growth, synaptogenesis, memory formation, and cognition. Using a Cre-based approach to visually distinguish pre-existing from newly formed pyramidal neurons for patch-clamp recordings, we learn that rhEPO treatment differentially affects excitatory and inhibitory inputs. Our findings provide mechanistic insight into how EPO modulates neuronal functions and networks Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Autism Annex: The STAR Autism Support Podcast
Neuroscience and Genetics: Dr. Geschwind on the Science of Autism

Autism Annex: The STAR Autism Support Podcast

Play Episode Listen Later Feb 2, 2023 26:07 Transcription Available


Dr. Daniel Geschwind is a distinguished professor of neurology, psychiatry, and human genetics at UCLA, and one of the world's leading experts in autism science.  In this episode he explains what we can learn about autism and the brain through cutting-edge neuroscience and genetic research. 

PaperPlayer biorxiv neuroscience
Senescent Schwann cells induced by aging and chronic denervation impair axonal regeneration after peripheral nerve injury

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Dec 8, 2022


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.07.519441v1?rss=1 Authors: Fuentes-Flores, A., Geronimo-Olvera, C., Necunir-Ibarra, D. S., Patel, S. K., Bons, J., Wright, M. C., Geschwind, D., Höke, A., Gomez-Sanchez, J. A., Schilling, B., Campisi, J., Court, F. A. Abstract: After peripheral nerve injuries, successful axonal growth and functional recovery requires the reprogramming of Schwann cells into a reparative phenotype, a process dependent on the activation of the transcription factor c-Jun. Nevertheless, axonal regeneration is greatly impaired in aged organisms or after chronic denervation leading to important clinical problems. This regenerative failure has been associated to a diminished c-Jun expression by Schwann cells, but whether the inability of these cells to maintain a repair state is associated to the transition into a phenotype inhibitory for axonal growth, has not been evaluated so far. We find that repair Schwann cells transitions into a senescent phenotype, characterized by diminished c-Jun expression and secretion of factor inhibitory for axonal regeneration in both aging and chronic denervation. In both conditions, elimination of senescent Schwann cells by systemic senolytic drug treatment or genetic targeting improves nerve regeneration and functional recovery in aging and chronic denervation, associated with an upregulation of c-Jun expression and a decrease in nerve inflammation. This work provides the first characterization of senescent Schwann cells and their impact over axonal regeneration in aging and chronic denervation, opening new avenues for enhancing regeneration, and functional recovery after peripheral nerve injuries. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Bullet und Fist
Folge 27: HOUSE OF FLYING DAGGERS oder GESCHWIND WIE DER WIND

Bullet und Fist

Play Episode Listen Later Nov 23, 2022 110:20


Das Trio Infernale begibt sich in die Wälder voller Emotionen, Ränkespielen und natürlich gibt es auch auf die Nuss. Spätestens wenn die Kerleim Cast von irgendwelchen Inseln voller Frauen schwadronieren und unser Held einen auf Wind macht. Dass es dabei natürlich höchst mayestetisch bleibt, dafür sorgt das Wuxia-Genre im Alleingang.. Kommt mit uns in eine wundervolle Abkehr vom Actionallerlei. Liebe und Action, selten passte es so formvollendet wie hier. Das Schallwellenglockenspiel haben wir aber alle drei eher wenig kapiert, ist aber egal, weil schön!! Viel Spaß!

Slovakia Today, English Language Current Affairs Programme from Slovak Radio
RERUN: TRACING RUDOLF GESCHWIND - part V - Diaries. (13.10.2022 16:00)

Slovakia Today, English Language Current Affairs Programme from Slovak Radio

Play Episode Listen Later Oct 13, 2022 31:49


Following the news bulletin we will continue in the series about the rose breeder Rudolf Geschwind. In the 5th part, we trace the mystery of the now world famous rose breeder's lost diaries. Are they in Slovakia?

PaperPlayer biorxiv neuroscience
Single-cell analysis characterizes non-enhancing region of recurrent high-grade glioma

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Oct 13, 2022


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.10.10.511639v1?rss=1 Authors: Patel, K. S., Tessema, K. K., Kawaguchi, R., Alvarado, A. G., Muthukrishnan, S. D. D., Hagiwara, A., Swarup, V., Liau, L. M., Wang, A. C., Yong, W., Geschwind, D., Nakano, I., Goldman, S., Everson, R., Ellingson, B., Kornblum, H. Abstract: Both therapy for and molecular investigations into high-grade glioma largely focus on the contrast-enhancing (CE) portion of the tumor. However, given the invasive nature of glioma, residual tumor cells responsible for recurrence exist in the peripheral, non-enhancing (NE) region. Single-cell/single-nucleus RNA-sequencing and subsequent bioinformatics analyses offer a flexible and scalable framework that allows powerful examination of tumor and non-tumor cell subpopulations across various contexts. In this study, we used pre-operative magnetic resonance images to prospectively identify biopsy targets in the CE region and NE sites that lie 0.5-2.0 cm beyond the CE edge from multiple pathologically and molecularly distinct recurrent high-grade gliomas and leveraged single-nucleus RNA-sequencing to generate over 30,000 individual RNA profiles. We analyzed multiple glioma cellular states, non-malignant cell types, and cell-cell interaction patterns, all of which revealed both conserved and patient-specific features. Recurrent gliomas recapitulate the previously reported cellular heterogeneity of primary gliomas. Systematic comparison of the CE and NE regions identified altered composition of malignant and non-malignant cell compartments, as well as cell type- and patient-specific differences in gene expression and pathway activation profiles. We established that NE regions up to 1.5 cm beyond the CE edge contain up to 60% infiltrating malignant cells, of which a significant subset are actively proliferating. These NE glioma cells are preferentially in OPC-like and NPC-like rather than MES-like cellular states. NE cells have altered gene expression patterns, with specific upregulation of certain genes like DGKB and OPHN1 relative to CE regions. We built an integrated atlas of cell-cell communication networks among malignant and non-malignant subpopulations in the two regions of glioma and identified a significantly rewired connectome in the NE regions of all tumors. With respect to tumor-immune interactions, NE regions had decreased numbers of T cells and myeloid cells, along with decreased HLA:CD8 signaling between glioma and immune cells, suggesting decreased immune detection and cell mediated immunity. Furthermore, our findings suggest glioma cells in NE regions maintain interactions with non-malignant neural tissue. Overall, we characterize the NE region in all pathological subtypes of recurrent high-grade glioma and identify possible mechanisms driving progression and recurrence, as well as areas of future therapeutic study. Copy rights belong to original authors. Visit the link for more info Podcast created by PaperPlayer

I Want To Believe: Season 2
S5 Death and Exorcism | Halloween Special 2022

I Want To Believe: Season 2

Play Episode Listen Later Oct 1, 2022 37:28


I Want to Believe the Podcast – S5 2022 Halloween Special – Death and Exorcism Open: Exorcism of Emily Rose Trailer | Closing song: Eyes Without A Face by Billy Idol Clips throughout episode: Buzzfeed Unsolved Welcome to the I Want to Believe podcast and our Halloween special for 2022! A familiar voice is back with us for the spooky season, friend to the show, Valerie Lofaso. The Exorcism of Emily Rose was a 2005 horror movie about a young woman who had become possessed by several demons. The movie was based on true events… in this episode, we'll be sharing those events with you. Anneliese Michel, the woman that Emily Rose was based on, grew up devoutly Catholic in Bavaria, West Germany in the 1960s. When she was 16, one day at school she blacked out and was seen walking around in dazed state and unresponsive to those who approached her. Though Anneliese did not remember what happened, friends and family told her of the trance-like state she had been in. Little did they know, this was only the beginning. After numerous exorcisms of Anneliese ended in tragedy, her parents and priests involved were charged with her death. Was it temporal lobe epilepsy and Geschwind syndrome as the prosecution presented? Or was it actual demonic possession, which the defense argued? Listen to the episode for the whole story and decide for yourself. - My latest spooktacular book, We Only Come Out at Night, is available for purchase. This book is a collection of short horror stories and is a great companion piece for your Halloween festivities. You can get it at: SlevikStore.Company.Site or at the Green Hand Bookshop in Portland, Maine. Valerie's Tangled Web of Friends book series can be found on all online booksellers: B&N | Amazon | Bookshop.org | Goodreads Lastly, my documentary, Otherworldly Amor has a new home. It is streaming exclusively on ParaFlixx Paranormal+ this is a subscription service much like Netflix and offers monthly or yearly subscriptions. Once subscribed, you have access to not only Otherworldly Amor but hundreds of other paranormal shows, documentaries and even horror movies. Another great tool for harnessing your Halloween hellscapes. By using the code OTHERWORLDLYAMOR10 at checkout, you can get 10% off your first 3 months. Sources: All That's Interesting | NCBI | Diabolical Confusions --- Support this podcast: https://anchor.fm/207believe/support

Spectrum Autism Research
Autism researcher Daniel Geschwind nets top National Academies prize

Spectrum Autism Research

Play Episode Listen Later Sep 26, 2022 2:41


The prize recognizes Geschwind's contributions to our understanding of autism genetics. The post Autism researcher Daniel Geschwind nets top National Academies prize appeared first on Spectrum | Autism Research News.

Spectrum Autism Research
Autism researcher Daniel Geschwind nets top National Academies prize

Spectrum Autism Research

Play Episode Listen Later Sep 15, 2022 2:41


The prize recognizes Geschwind's contributions to our understanding of autism genetics.

Spectrum Autism Research
Autism researcher Daniel Geschwind nets top National Academies prize

Spectrum Autism Research

Play Episode Listen Later Sep 15, 2022 2:41


The prize recognizes Geschwind's contributions to our understanding of autism genetics.

PaperPlayer biorxiv neuroscience
The genetics of cortical organisation and development: a study of 2,347 neuroimaging phenotypes

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Sep 8, 2022


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.09.08.507084v1?rss=1 Authors: Warrier, V., Stauffer, E.-M., Huang, Q. Q., Wigdor, E. M., Slob, E. A. W., Seidlitz, J., Ronan, L., Valk, S. L., Mallard, T. T., Grotzinger, A. D., Romero-Garcia, R., Baron-Cohen, S., Geschwind, D. H., Lancaster, M., Murray, G. K., Gandal, M. J., Alexander-Bloch, A., Won, H., Martin, H. C., Bullmore, E. T., Bethlehem, R. A. I. Abstract: Our understanding of the genetic architecture of the human cerebral cortex is limited both in terms of the diversity of brain structural phenotypes and the anatomical granularity of their associations with genetic variants. Here, we conducted genome-wide association meta-analysis of 13 structural and diffusion magnetic resonance imaging derived cortical phenotypes, measured globally and at 180 bilaterally averaged regions in 36,843 individuals from the UK Biobank and the ABCD cohorts. These phenotypes include cortical thickness, surface area, grey matter volume, and measures of folding, neurite density, and water diffusion. We identified 4,349 experiment-wide significant loci associated with global and regional phenotypes. Multiple lines of analyses identified four genetic latent structures and causal relationships between surface area and some measures of cortical folding. These latent structures partly relate to different underlying gene expression trajectories during development and are enriched for different cell types. We also identified differential enrichment for neurodevelopmental and constrained genes and demonstrate that common genetic variants associated with surface area and volume specifically are associated with cephalic disorders. Finally, we identified complex inter-phenotype and inter-regional genetic relationships among the 13 phenotypes which reflect developmental differences among them. These analyses help refine the role of common genetic variants in human cortical development and organisation. Copy rights belong to original authors. Visit the link for more info Podcast created by PaperPlayer

Slovakia Today, English Language Current Affairs Programme from Slovak Radio
RERUN: Lotta on KEXP. Roses by Geschwind. (2.6.2022 16:00)

Slovakia Today, English Language Current Affairs Programme from Slovak Radio

Play Episode Listen Later Jun 2, 2022 28:50


Reintroducing Slovak musician Lotta through her music with KEXP's Kevin Cole. Shortly ahead of the Rose festivity event in Dolna Krupa, western Slovakia, we map the world famous cultivars that were bred in Krupina, central Slovakia.

StadtRadio Göttingen - Beiträge
Haushaltsdefizit, Innenstadtentwicklung und Baumaßnahmen – Duderstadts Bürgermeister Thorsten Feike im Interview

StadtRadio Göttingen - Beiträge

Play Episode Listen Later Feb 16, 2022 7:52


Geschwind wie der Wind soll das Internet in Duderstadt werden. Die Stadt hatte erst kürzlich bekannt gegeben, dass die Arbeiten im Frühjahr starten sollen. Und auch sonst gibt es einige Baustellen in der Eichsfeldstadt zu beackern. Allen voran dürfte die Pandemie weiterhin das bestimmende Thema sein und den Haushalt diktieren. Über all diese Themen hat Steffen Hackbarth heute Morgen mit Bürgermeister Thorsten Feike gesprochen.

Cybr Podcast
From baker to Full-Stack Developer with Miwha Geschwind

Cybr Podcast

Play Episode Listen Later Nov 15, 2021 28:48


I met Miwha at a local meetup here in Denver, and we started talking about her job, how she got that job, and what led her down the path of web development. She told me that she used to have her own pastry baking business but a series of events led to her joining a coding boot camp, and then getting a full-time dev job soon after that. Then, as we were planning this episode, she announced that she had just landed yet another job! So for this episode, Miwha shares her story with us so that 1) if anyone listening is thinking of transitioning to the IT industry, they can see that it's absolutely possible, and 2) so that we can get practical tips on how to land a job in the IT industry and in present times.

Slovakia Today, English Language Current Affairs Programme from Slovak Radio
RERUN: Tracing Rudolf Geschwind - part 3 - Proving Geschwind. (28.10.2021 16:00)

Slovakia Today, English Language Current Affairs Programme from Slovak Radio

Play Episode Listen Later Oct 28, 2021 30:49


In this part of our series tracing the work of this significant rose breeder, we ask experts in Europa Rosarium, Sangerhausen, Germany, Rosenkultivarium in Baden, Austria, and Technical University in Zvolen, how to identify the origin of the rose.

Bakom bokhyllan
#37 Varför ska man ha en mentor?

Bakom bokhyllan

Play Episode Listen Later Sep 28, 2021 21:09


Den akademiska världen kan vara svårnavigerad, även för den som har kommit en bit på sin forskarkarriär. Då kan det vara skönt att ha en mer erfaren forskare att vända sig till. Men vad innebär det att ha, eller att vara, en mentor? I höstens första avsnitt av universitetsbibliotekets podd Bakom bokhyllan får lyssnarna möta mentorn Laura Alvarez Lopez och den tidigare mentanden Britta Zetterström Geschwind som berättar om sina erfarenheter. Båda deltog i förra omgången av Humanvetenskapliga områdets mentorsprogram på Stockholms universitet, som startar på nytt hösten 2021.

The Crossbar Podcast
Ajax Season Preview with Marc Geschwind

The Crossbar Podcast

Play Episode Listen Later Aug 16, 2021 36:10


In the first installment of my Dutch Eredivisie season preview series, I chat with Marc Geschwind. Marc is a co-founder of the popular Twitter account @EifSoccer, and you can follow his personal account @MarcGeschwind for all his thoughts on Ajax and football more broadly. Be sure to follow the show on Twitter as well @thecrossbarpost and check out our new website at crossbarpost.nl. Happy listening!

Enneagrampodden
Avsnitt 20 Ledarstilar del 3

Enneagrampodden

Play Episode Listen Later Jul 6, 2021 71:06


Dags för säsongens sista avsnitt! Vi rundar av våra samtal om nio olika ledarstilar med att intervjua tre ledare. Vi arbetar både med dem och deras team - och de är väl insatta i sina strategier. Lyssna på hur de ser på sitt ledarskap och vilka styrkor och utmaningar de har - tre personer, tre helt olika erfarenheter. STORT tack för er medverkan; Åse Geschwind från Trafikkontoret med Fyrans strategi, Elin Lörelius från Uppsala Universitet och Robert Fredell från Svensk Ventilationsservice.

Zurück in deine Kraft - Für einen bewussten und achtsamen Umgang mit Trauer und Verlust
Wie du den Verlust eines geliebten Tieres verarbeiten kannst - Inspirationsgespräch mit Alice Geschwind

Zurück in deine Kraft - Für einen bewussten und achtsamen Umgang mit Trauer und Verlust

Play Episode Listen Later Jun 13, 2021 58:39


Herzlich willkommen zur heutigen Folge von „Zurück in deine Kraft – Für einen bewussten & achtsamen Umgang mit Trauer und Verlust“. Ich freue mich sehr, dass du hier bist und dir damit Zeit für dich und dein Wohlbefinden schenkst. In dieser Folge ist die liebe Alice Geschwind zu Gast. Alice erzählt von dem Verlust ihres geliebten Familienhundes. Sie berichtet, wie sie mit dem Verlust umgegangen ist und wie ihr verstorbener Hund jetzt immer noch ganz nahe bei ihr ist. Du erfährst in dieser Folge: • wie Du mit Deiner Trauer um ein geliebtes Haustier umgehen kannst. • wie Dein verstorbenes Haustier als Krafttier immer bei dir bleibt. • was Dankbarkeit im Trauerprozess verändert. • warum das Leben immer für uns ist. Durch den Trauerprozess hat Alice ihr Herzensprojekt entwickelt: Die Herzensbox! Die Herzensbox ist die von Alice entwickelte Starterbox für mehr tägliche Selbstliebe. Die Herzensbox ist die Eintrittskarte für ein glückliches und erfülltes Leben. Du findest Alice und die Herzensbox auf Instagram unter: alice_geschwind und über ihre Website und den Online Shop: www.herzensbox.de Ich wünsche dir viel Inspiration und ganz viel Spaß beim Zuhören und freue mich auf dein Feedback. Schreibe mir hierfür gerne in dem Post von heute auf Instagram (backtohappiness_coaching), dein Feedback zu der Folge. Alle Informationen zum Meditations-Mentoring für Trauernde findest du hier: https://www.backtohappiness.de/meditationsmentoring/ Kennst du schon mein Trauerjournal, das dich 6 Monate in Form von täglichen Schreibimpulsen durch deine Trauer begleitet? Du kannst es hier bestellen: https://www.backtohappiness.de/trauerjournal/ Wenn du näher mit mir zusammenarbeiten möchtest, buche gerne eine kostenlose backtohappiness.session und wir schauen, ob ich dich mit meiner Arbeit noch tiefgehender unterstützen kann: https://www.backtohappiness.de/angebote/ Und hier findest du noch mehr über mich: Meine Webseite: www.backtohappiness.de Instagram: backtohappiness_coaching Facebook: Backtohappiness Youtube: backtohappiness by Vanessa Rippegarten Freebie: Hol dir hier 9 Tipps, die mir aus meiner Trauer herausgeholfen haben: www.backtohappiness.de Du bist nicht alleine in deiner Trauer! Alles Liebe, deine Vanessa

Brain Talk | Being Patient for Alzheimer's & dementia patients & caregivers
What Are Rapidly Progressive Dementias? with Dr. Michael Geschwind

Brain Talk | Being Patient for Alzheimer's & dementia patients & caregivers

Play Episode Listen Later May 4, 2021 37:29


Dr. Michael Geschwind, professor of neurology at the University of California San Francisco Memory and Aging Center, speaks about the symptoms, diagnoses and treatments of rapidly progressive dementias.

Welcome to Dave's Music Room
The ThreeBees

Welcome to Dave's Music Room

Play Episode Listen Later Apr 24, 2021 162:19


Episode #9: The ThreeBees Uploaded: April 24, 2021 Carl Maria von Weber, orch. by Hector Berlioz: Aufforderung zum Tanz, Op. 65, J. 260 [10:22] Radio-Symphonie-Orchester Berlin Ferenc Fricsay, conductor DEUTSCHE GRAMMOPHON MUSIKFEST 415 789-2 Franz Biebl: Ave Maria* [7:30] arr. Tom Hart & Joseph Jennings: Steal Away to Jesus+ [5:07] Chanticleer Joseph Jennings, director CHANTICLEER RECORDS *CR-8803, +CR-8801 Johann Sebastian Bach: Cantata, “Ich Habe Genug”, BWV 82 Aria: Ich Habe Genug [7:43] Recitative: Ich Habe Genug. Mein Trost Ist Nur Allein [1:28] Aria: Schlummert Ein, Ihr Matten Augen [10:00] Recitative: Mein Gott! Wann Kommt Das Schönen Nun [0:53] Aria: Ich Freue Mich Auf Meinen Tod [3:44] Lorraine Hunt Lieberson, mezzo-soprano The Orchestra of Emmanuel Music Craig Smith, conductor NONESUCH PRCD 301093 Jorge Ben Jor: Pais Tropical [2:43] Sergio Mendes & Brasil ‘71 A&M RECORDS 25TH ANNIVERSARY CD 2516 Jean Bertet & Vincent Scotto: Elle vendait des petits gâteaux [2:34] Félix Mayol, vocals Unidentified orchestra DISQUES XX I – 21 RECORDS XXI-CD 2 1450 Jean-Loup Dabadie, Pierre Delanoë & Jean-Pierre Bourtayre: L'Amour [4:20] Mireille Mathieu, vocals Orchestra conducted by Jean Claudric CBS CK-90767 Spike Milligan: You gotta go oow! [2:42] Spike Milligan, vocals The Massed Alberts HUX RECORDS HUX 015 Kate Bush: Babooshka [3:29] Kate Bush, vocals with ensemble EMI AMERICA CDP 7 46414 2 Ludwig van Beethoven: Piano Sonata No. 28 in A Major, Op. 101 I. Etwas lebhaft mit der innigsten Empfindung [5:15] II. Lebhaft. Marschmaßig [6:22] III. Langsam und sehnsuchtsvoll [3:28] IV. Geschwind, doch nicht zu sehr, und mit Entschlossenheit [8:18] Andrew Rangell, piano DORIAN RECORDINGS DOR-90143 Johannes Brahms: Symphony No. 4 in E Minor, Op. 98 I. Allegro non troppo [11:20] II. Andante moderato [12:46] III. Allegro giocoso [6:35] IV. Allegro energico e passionate [9:44] Royal Philharmonic Orchestra Fritz Reiner READER'S DIGEST 285-0011 The Orpheus Choir of Toronto website: http://orpheuschoirtoronto.com

Dein Heile Welt Podcast
Kraftvolle Rituale für mehr Selbstliebe - Interview mit Alice Geschwind

Dein Heile Welt Podcast

Play Episode Listen Later Apr 5, 2021 37:00


Schön, dass Du wieder einschaltet hast! Diese Folge möchte ich Dir sehr ans Herz legen, weil es um eines der wichtigsten Dinge in unserem Leben geht: die Liebe zu uns selbst. Mit Alice spreche ich über Rituale, die Dich stärken und Deine Energie anheben. In dieser Folge erfährst Du: - warum sich durch Dankbarkeit ALLES in Deinem Leben verändert - welche Kraft in täglichen Selbstliebe-Ritualen liegt - welche Rolle die Kommunikation mit Dir selbst spielt - warum Aufschreiben so wichtig ist - was es mit der Herzensbox auf sich hat Mein heutiger Interviewgast ist Alice Geschwind. Alice ist Gründerin und Erfinderin der Herzensbox. Die Herzensbox ist eine von ihr persönlich entwickelte Starterbox für mehr tägliche Selbstliebe. Ihre Vision ist es ihren Kunden mit der Box von Herz zu Herz die Eintrittskarte zu einem Leben in Fülle zu geben. Sie zeigt Dir, wie Du durch einfache, kleine Handlungen im Alltag Dein Leben von Grund auf verändern kannst. Durch all die Dinge, die sie in der Herzensbox zusammengestellt hat, hat sich ihr Leben radikal verändert. Sie war früher nicht der Mensch, der ich sie heute ist. Als sie morgens das Haus verlassen hat, hat ich sie sich ausschließlich auf das Negative fokussiert. Das hat sich durch ihren ganzen Tag und durch die gesamte Woche gezogen. Heute ist es das komplette Gegenteil. Sie hat mit viel Liebe die Inhalte der Herzensbox zusammengestellt und die Dinge so zusammengefasst, wie sie ihr am Anfang geholfen haben. Neben der Herzensbox begleitet sie Menschen im Herzenscoaching dabei in die tiefe Liebe für sich und das Leben zu kommen. Wenn Dir diese Folge gefallen hat, dann freue ich mich, wenn Du sie teilst, den Podcast abonnierst und eine Rezension auf iTunes hinterlässt. Damit hilfst Du mir, dass noch mehr Menschen auf ihrem Weg der Transformation und persönlichen Weiterentwicklung unterstützt werden. Von Herzen DANKE! Und jetzt: viel Spaß beim Zuhören... __________ Hier findest Du mehr über Alice: - Homepage: https://herzensbox.de - Instagram: https://www.instagram.com/alice_geschwind/ __________ Hier findest Du mehr über mich: - Homepage: https://annalenavolk.com/ - Instagram: https://www.instagram.com/annalena_volk/ - Youtube: https://www.youtube.com/c/annalenavolk - Facebook: https://www.facebook.com/volkannalena Hast Du eine Frage? Dann schreibe mir eine Mail an: hallo@dein-heile-welt-podcast.de __________ Auf Deine Heile Welt! Deine Annalena :-)

Länderreport - Deutschlandfunk Kultur
Verkehrskonzept für Wiesbaden - Mit dem E-Bike geschwind in die Innenstadt radeln

Länderreport - Deutschlandfunk Kultur

Play Episode Listen Later Feb 15, 2021 8:07


Ohne Auto von Wiesbaden nach Mainz zu gelangen, ist kaum möglich. Zudem haben die Bürger den Bau einer neuen Straßenbahn abgelehnt. Jetzt soll eine alte Bahntrasse aktiviert werden und ein Radschnellweg gebaut werden. Von Ludger Fittkau www.deutschlandfunkkultur.de, Länderreport Hören bis: 19.01.2038 04:14 Direkter Link zur Audiodatei

Finding Genius Podcast
Making Sense of Sequencing: Exome Sequencing Analysis and What's Next with Dr. Daniel Geschwind

Finding Genius Podcast

Play Episode Listen Later Jan 16, 2021 33:34


Dr. Daniel Geschwind Bio: Dr. Geschwind is the Gordon and Virginia MacDonald Distinguished Professor of Human Genetics, Neurology and Psychiatry at UCLA. In his capacity as Senior Associate Dean and Associate Vice Chancellor of Precision Health, he leads the Institute for Precision Health (IPH) at UCLA, where he oversees campus precision health initiatives. In his laboratory, his group has pioneered the application of systems biology methods in neurologic and psychiatric disease, with a focus on autism spectrum disorders (ASD) and neurodegenerative conditions. Dr. Geschwind is a pioneer in the transcriptomic and functional genomic analyses of the nervous system. His laboratory showed that gene co-expression has a reproducible network structure that can be used to understand neurobiological mechanisms in health and disease. He led the first studies to define the molecular pathology of autism and several other major psychiatric disorders, and has made major contributions to defining the genetic basis of autism. He demonstrated the utility of using gene network approaches to discover new pathways involved in neurodegeneration and new approaches to facilitate neural regeneration.  More recently, his laboratory demonstrated how knowledge of 3-dimensional chromatin structure can be used to understand the functional impact of human genetic variation. Dr. Geschwind has trained over 70 graduate students and post-doctoral research fellows, and is among the highest cited scientists in neurology, neuroscience and genetics (H index > 140). In addition to serving on several scientific advisory boards, including the Faculty of 1000 Medicine, the Scientific Advisory Board for the Allen Institute for Brain Science, the NIMH Advisory Council and the NIH Council of Councils, he currently serves on the editorial boards of the journals Cell, Neuron and Science. He has received several awards for his laboratory's work is an elected Member of the American Association of Physicians and the National Academy of Medicine.   What can big data and genomics offer the individual regarding medical treatment? Dr. Daniel Geschwind is here to explain exome sequencing data analysis as well as how this field might expand and progress. Listen and learn What makes up our genome, how to understand the terms for each part, like exon, intron, and exome, and what parts are effected epigenetically; Why genomics testing still focuses on that 2 to 3 percent of the genome called the exome that codes for proteins; and How sequencing will broaden and change, making preventative care that much more effective for certain patients and more. Dr. Daniel Geschwind is the Gordon and Virginia MacDonald Distinguished Professor in Neurology, Psychiatry, and Human Genetics; the Senior Associate Dean and Associate Vice Chancellor for Precision Health at UCLA; and the director of the Center for Autism Research and Treatment at the Semel Institute at UCLA David Geffen School of Medicine. He opens up the world of genomics for listeners, explaining why an exome sequencing test is the center of precision medicine currently. He explains how the exome is composed of the 3% of your genome that actually codes for protein sequences. What's the rest of the genome up to? Well, scientists believe that remainder of your genome is busy regulating those sequences, determining levels and turning gene expressions on and off.  He explains how scientists use the exome sequencing process. In fact, the majority of people who say they've been sequenced mean, in fact, that their exome has been sequenced. Whole genome sequencing costs about three times as much but offers scientists the same information at this point. However, he thinks this will soon change. As the exome sequencing project continues and our knowledge accumulates, the benefits will increase from whole genome sequencing. The costs are likely to drop as well.  Once it gets inexpensive enough and we have sequenced hundreds of millions of patients with a variety of disorders, we will have much better predictive power.  For more information, he suggests UCLA's Precision Health website. Available on Apple Podcasts: apple.co/2Os0myK

PaperPlayer biorxiv neuroscience
Aberrant gliogenesis and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Nov 19, 2020


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.11.19.387639v1?rss=1 Authors: Trudler, D., Ghatak, S., Parker, J., Talantova, M., Grabauskas, T., Noveral, S. M., Teranaka, M., Luevanos, M., Dolatabadi, N., Bakker, C., Lopez, K., Sultan, A., Chan, A., Choi, Y., Kawaguchi, R., Schork, N., Stankiewicz, P., Garcia-Bassets, I., Kozbial, P., Rosenfeld, M. G., Nakanishi, N., Geschwind, D., Chan, S. F., Ambasudhan, R., Lipton, S. A. Abstract: MEF2C has been shown to be a critical transcription factor for neurodevelopment, whose loss-of-function mutation in humans results in MEF2C haploinsufficiency syndrome (MHS), a severe form of autism spectrum disorder (ASD)/intellectual disability (ID). Here, we use patient hiPSC-derived cerebrocortical neurons and cerebral organoids to characterize MHS deficits. Unexpectedly, we found an aberrant micro-RNA-mediated gliogenesis pathway that contributes to decreased neurogenesis. We also demonstrate network-level hyperexcitability in neurons, as evidenced by excessive synaptic and extrasynaptic activity contributing to excitatory/inhibitory (E/I) imbalance. Notably, the extrasynaptic NMDA receptor antagonist, NitroSynapsin, corrects this aberrant electrical activity associated with abnormal phenotypes. During neurodevelopment, MEF2C regulates many ASD-associated gene networks suggesting that our approach may lead to personalized therapy for multiple forms of ASD. Copy rights belong to original authors. Visit the link for more info

Die Slowakei hautnah, Magazin über die Slowakei in deutscher Sprache
Sonderausgabe im Zeichen der Rosen: Auf der Spur des Rosenzüchters Rudolf Josef Geschwind. (12.11.2020 15:30)

Die Slowakei hautnah, Magazin über die Slowakei in deutscher Sprache

Play Episode Listen Later Nov 12, 2020 22:53


Nachrichten.Tagesthema. Magazin - Sondeausgabe im Zeichen der Rosen: Auf der Spur des Rosenzüchters Rudolf Josef Geschwind

Slovakia Today, English Language Current Affairs Programme from Slovak Radio
Slovakia Today, English Language Current Affairs Programme from Slovak Radio (12.11.2020 16:00)

Slovakia Today, English Language Current Affairs Programme from Slovak Radio

Play Episode Listen Later Nov 12, 2020


Another part of RSI series presenting the legacy of 19th century rose breeder who worked and lived in Krupina, now central Slovakia. Today, a city walk linking spots of Geschwind life with Miroslav Lukáč from Andrej Sládkovič Museum as the guide.

Slovensko dnes, magazín o Slovensku
Zabudnuté osobnosti - Rudolf Geschwind a príbeh jeho ruží. (23.10.2020 17:30)

Slovensko dnes, magazín o Slovensku

Play Episode Listen Later Oct 23, 2020 25:41


Správy.Téma dňa. Zabudnuté osobnosti - Rudolf Geschwind a príbeh jeho ruží.

Don't Leave The House
Poor Baby Janet and Broken Kneecaps

Don't Leave The House

Play Episode Listen Later Oct 20, 2020 64:12


Thanks so much for tuning in to episode 33 of Don't Leave the House! This week Haley gets into the Enfield Poltergeist, and Amanda tells the story of the real Exorcism of Emily Rose, Anneliese Michel. Sources for this episode are: Daileymail.co.uk, BBC.co, And that's why we drink podcast Episode 56, https://allthatsinteresting.com/anneliese-michel-exorcism, https://en.wikipedia.org/wiki/Anneliese_Michel, https://www.epilepsy.com/learn/types-epilepsy-syndromes/temporal-lobe-epilepsy-aka-tle#:~:text=Temporal%20Lobe%20Epilepsy%20%28TLE%29%201%20Temporal%20lobe%20epilepsy,for%20memory%20and%20mood%20difficulties.%20More%20items...%20, https://en.wikipedia.org/wiki/Geschwind_syndrome. If you would like to support our growth, you can do so at anchor.fm/dontleavethehouse or patreon.com/dontleavethehouse. You can find us on Facebook, Instagram or Twitter. Contact us at dontleavethehousepodcast@gmail.com. We TRULY appreciate you!!! --- Support this podcast: https://anchor.fm/dontleavethehouse/support

PaperPlayer biorxiv neuroscience
Maternal immune activation during pregnancy alters early neurobehavioral development in nonhuman primate offspring

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Jul 4, 2020


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.02.185363v1?rss=1 Authors: Vlasova, R. M., Iosif, A.-M., Ryan, A. M., Murai, T., Lesh, T. A., Rowland, D. J., Bennett, J., Hogrefe, C. E., Maddock, R. J., Gandal, M. J., Geschwind, D. H., Schumann, C. M., Van de Water, J., McAllister, A. K., Carter, C. S., Styner, M. A., Amaral, D. G., Bauman, M. D. Abstract: Background: Human epidemiologic studies have implicated exposure to infectious or inflammatory insults during gestation in the etiology of neurodevelopmental disorders. Rodent models of maternal immune activation (MIA) have identified the maternal immune response as the critical link between maternal infection and aberrant brain and behavior development in offspring. The nonhuman primate MIA model provides an opportunity to maximize the translational utility of this model in a species more closely related to humans. Methods: Here we evaluate the effects of MIA on brain and behavioral development in the rhesus monkey (Macaca mulatta). A modified form of the viral mimic, Polyinosinic-polycytidylic acid (PolyIC), was delivered to pregnant rhesus monkeys (n=14) in the late first trimester to stimulate a maternal immune response. Control dams received saline injections at the same gestational time points (n=10) or were untreated (n=4). Results: MIA-treated dams exhibited a strong immune response as indexed by transient increases in sickness behavior, temperature and inflammatory cytokines. MIA-exposed offspring developed species typical milestones and demonstrate subtle changes in early in social development. However, magnetic resonance imaging demonstrated significant gray matter volume reductions in prefrontal and frontal cortices at 6, 12 and 24 months of age. Conclusions: These findings provide new insights into the emergence of neuropathology in MIA-exposed primates and have implications for the pathophysiology of human psychiatric disorders associated with maternal gestational infection. Copy rights belong to original authors. Visit the link for more info

Leaderin von Morgen
Von Pessimismus & Angst zum strahlenden Herzensmensch - Interview Alice Geschwind

Leaderin von Morgen

Play Episode Listen Later Jun 15, 2020 32:48


Ich hatte ein unglaublich inspirierendes und tiefgründiges Gespräch mit der lieben Alice. Sie erzählt von ihrer Transformation und wie sie es schafft sich immer wieder zu verändern und weiterzuentwickeln. Lange Zeit war Alice dem Leben gegenüber negativ eingestellt, oft ängstlich oder traurig - bis sie irgendwann gemerkt hat, so kann es nicht weitergehen. Ihre Transformation ist auch ihrem Umfeld nicht verborgen geblieben und sie wurde immer wieder auf ihre Veränderung angesprochen. Daraus hat sich dann sogar eine Business Idee entwickelt. Wie sprechen darüber: wie sie es geschafft hat von Angst, Traurigkeit & Negativität zu einem glücklichen, selbstbestimmten und dankbaren Leben warum Selbstliebe und Dankbarkeit so unglaublich machtvoll sind wie du von der Opferrolle in die Eigenverantwortung kommen kannst von der Vision zur Umsetzung - die ersten Schritte in deinem Business warum unser Umfeld so entscheidend ist und so vieles mehr Heute ist Alice Gründerin der Herzensbox, die Eintrittskarte zu einem glücklichen und selbstbestimmten Leben in Fülle. Alle Infos zu Alice und ihrer Herzensbox: Link Alice: https://herzensbox.de/ https://www.instagram.com/alice_geschwind/ Link Christiane: https://www.christianeoster.de/ https://www.instagram.com/christiane.oster/ E-Mail: Coaching@Christianeoster.de

Shared Madness
Episode 11: The Exorcism of Anneliese Michel

Shared Madness

Play Episode Listen Later May 24, 2020 18:43


There was a movie that came out in 2005 called The Exorcism of Emily Rose. Very few people know that this movie was actually based on the real life of a German girl named Anneliese Michel. Ann Elisabeth, AKA Anneliese, Michel was born September 21st, 1952 in Leiblfing, Bavaria, West Germany to parents Josef and Anna. Anneliese had some psychiatric issues that included seizures as well as events in which she would black out and walk around in a trance-like state. After years of medical assistance in a psychiatric hospital, Anneliese's family and friends came to the conclusion that she was under demonic possession and sought help from the Catholic Church. After 67 exorcism sessions, Anneliese was finally released of the demons that were inside of her. Unfortunately, however, Anneliese died in her home on July 1st, 1976. Her death caused a lot of backlash against her family as well as the priest that performed the exorcisms, causing this case to be one of the few exorcisms to go to court. Was she under demonic possession, or was it just her Geschwind syndrome epilepsy? Sources for this episode:  Wikipedia Time magazine Chasingthefrog.com Allthatsinteresting.com Buzzfeed Unsolved video: https://www.youtube.com/watch?v=1KgSp94nCZw&feature=emb_rel_pause --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

PaperPlayer biorxiv neuroscience
Neuronal and glial 3D chromatin architecture illustrates cellular etiology of brain disorders

PaperPlayer biorxiv neuroscience

Play Episode Listen Later May 16, 2020


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.05.14.096917v1?rss=1 Authors: Hu, B., Won, H., Mah, W., Park, R., Kassim, B., Spiess, K., Kozlenkov, A., Crowley, C. A., Pochareddy, S., Li, Y., Dracheva, S., Sestan, N., Akbarian, S., Geschwind, D. Abstract: Cellular heterogeneity in the human brain obscures the identification of robust cellular regulatory networks. Here we integrated genome-wide chromosome conformation in purified neurons and glia with transcriptomic and enhancer profiles to build the gene regulatory landscape of two major cell classes in the human brain. Within glutamatergic and GABAergic neurons, we were able to link enhancers to their cognate genes via neuronal chromatin interaction profiles. These cell-type-specific regulatory landscapes were then leveraged to gain insight into the cellular etiology of several brain disorders. We found that Alzheimer's disease (AD)-associated epigenetic dysregulation was linked to neurons and oligodendrocytes, whereas genetic risk factors for AD highlighted microglia as a central cell type, suggesting that different cell types may confer risk to the disease via different genetic mechanisms. Moreover, neuronal subtype-specific annotation of genetic risk factors for schizophrenia and bipolar disorder identified shared (parvalbumin-expressing interneurons) and distinct cellular etiology (upper layer neurons for bipolar and deeper layer projection neurons for schizophrenia) between these two closely related psychiatric illnesses. Collectively, these findings shed new light on cell-type-specific gene regulatory networks in brain disorders. Copy rights belong to original authors. Visit the link for more info

Radio Cade
Creativity and the Brain

Radio Cade

Play Episode Listen Later May 13, 2020


“Creativity is finding unity in what appears to be diversity,” says Dr. Kenneth Heilman. Author of Creativity and the Brain, Heilman, a distinguished Professor Emeritus at the University of Florida, explains where creativity may reside in the brain, how it differs from raw intelligence, and how creative people actually think. Heilman has been fascinated by creativity since childhood. Almost killed by meningitis as an infant in 1938, he was saved by a doctor who had heard of a new treatment and tried it on Heilman. “Creativity has reduced a huge amount of suffering,” Heilman says. TRANSCRIPT: Intro: 0:01 Inventors and their inventions. Welcome to Radio Cade the podcast from the Cade Museum for Creativity and Invention in Gainesville, Florida. The museum is named after James Robert Cade, who invented Gatorade in 1965. My name is Richard Miles, we’ll introduce you to inventors and the things that motivate them, we’ll learn about their personal stories, how their inventions work and how their ideas get from the laboratory to the marketplace. Richard Miles: 0:38 Creativity in the brain, where can it be found? How does it differ from intelligence? And what are creative people like? I’m your host Richard Miles, today, My guest is Dr. Kenneth Heilman, distinguished professor emeritus at the University of Florida and author of surprise, a book called “Creativity and the Brain”. Welcome to Radio Cade Ken. Dr. Kenneth Heilman: 0:56 Thank you for inviting me. Richard Miles: 0:58 So Ken, like many of our guests on this show, you spent your career in Florida, but you were born in Brooklyn. So, the first thing I gotta ask is, Dodgers or Yankees? Let’s get that out of the way first. Dr. Kenneth Heilman: 1:09 Brooklyn Dodgers. But when they moved to LA, I stopped being a professional sports fan. Richard Miles: 1:16 So you didn’t switch to another team? You just gave up entirely on sports? Dr. Kenneth Heilman: 1:19 Well, you know, here was a team that was tremendously supportive and actually started integration with Jackie Robinson and what happened because they offered him a free stadium in the park and Patriot, the hell with the fans that have been watching him for all these years, we’re going to LA and I said, look, I don’t move for businesses.The hell with this I’m not watching this anymore. Richard Miles: 1:42 And that was a precursor of things, the calmest teams to abandon their cities, to go to other markets and so on during the expansion years. Okay. Well, now that we’ve got that most important question out of the way, let’s sort of dive straight into our topic. As you know, Phoebe and I, have always been interested in the neuroscience of creativity and I think the first time we met, probably about 2010, it was to get your ideas and some other folks at the University of Florida, we’re planning a big exhibit on the neuroscience of creativity. And so we needed to get smart, and we knew that you were one of the folks to talk to. So creativity is one of those terms that gets thrown around a lot and sometimes it’s defined in different ways. So why don’t I start by asking you to define creativity from your point of view, and then how does it differ from intelligence? But let’s start with that. Dr. Kenneth Heilman: 2:25 Okay. First of all, when I was in high school, I took a public speaking course, I got to seen it, but your teachings are remember, is thought by definitions and tell people how important it is. So we’ll start with the definitions. It depends where you look up creativity for different definitions. If you go to websites, for example, it says productive and mall by originality. So according to them, if I sat down in front of a word processor and randomly hit keys for days and days and days, it would be creative because it would be original. Nobody probably would hit the same keys and if I did it long enough, it would be productive, but you wouldn’t feel this would be creative. I think the best definition, but the same complete by Banowsky who said, creativity is fine in unity in what appears to be diversity. The only problem with this definition it is no mention of originality or productivity. So I think in the book and during lectures, when I define creativity is the ability to discover, understand, develop and express in a systematic fashion, novel, orderly relationships said , in other words, finding the thread that unites. Now, a lot of people in other definitions state, it must have value, and I never understood why they put it in and sure, great artists, and you never sell your painting and it burns or something. It doesn’t mean that it wasn’t creative. Even now. It has no value. So value, I’m not sure really defines it . It defines it and far as business people, but not as far as people who produced creative products. Now let me tell you about the second part. If you look at my yearbook at high school, all the way back then he says Ken Heilman wants to do medical research. And what happened when I was a little boy, I looked down at my arm and I noticed I had a scar right near the front on the top and I asked my mother, what is that mom? She said, oh, when you were an infant, you came down with meningococcal meningitis. And this was 1938 or 1939, and the doctor said we have no cure for it. He’s going to die. It turns out this doctor actually had an appointment that Columbia University and you were working on a new drug called sulfur drugs . And he actually lifted some out of the laboratory poets and my house did a cut down. That’s what the scar was for, gave it to me, and here it’s 79, 80 years later and I’m still here. And that really brought to mind how important creativity is. You inclined have suffered with diseases and so many other problems and when you think about all the wonderful things that we’ve done, when used appropriately, creativity has reduced a huge amount of suffering . So that’s why it’s always been a very important topic to me. Richard Miles: 5:31 So can you write it? Creativity is closely linked to raw intelligence, but it’s not quite the same thing? Is that correct? Dr. Kenneth Heilman: 5:38 Well, let me talk about intelligence and creativity. Okay. First of all, let me start by saying in general, when I’ve written about this, I talk about three major steps in the creative process. The first one is preparation, and that’s learning all the skills and knowledge that you need to be creative. The second one, I call creative innovation and that’s coming up with the creative ideas. And the third stage of course is production. Now I’m not going to discuss that at all, because that depends upon the domain of creativity. But what about IQ Willem , as you probably know, okay. With IQ, when initially it was early on used people call people who have IQ over 130, 140 geniuses. And genius implies that you’re tremendously creative. And it turns out there was a psychologist, I think at Stanford, whose name was Terman . And what Termin did was gave all the students and around San Francisco and all that area an IQ test that he developed called the Stanford Benet. And then he followed all these people along and it turns out some were very successful, some or just usual, but there were no Nobel prize winners that was in his genius class, but it turns out that there was two Nobel prize winners whose IQs were too low to be in term as geniuses that reached and got the Nobel prize. So one was Shockley who invented the transistor and you know what that’s meant to our world . And another one was Alvarez who helped develop the radar. They both won Nobel prizes, but they didn’t have IQs high enough to be included in terms of geniuses. So in general, people found out that later on, there was not a direct relationship between intelligence and creativity. And in general, a lot of people who’ve written about this say, you just need to be intelligent enough to learn the skills and knowledge in the creative domain that you’re doing. People have a cutoff of about 110 or 120 , but there is no direct relationship. Richard Miles: 7:53 So it’s more of a threshold factor, right? That once you reach that threshold of somewhere between 110 and 120, there’s not a correlation that the smarter you are, the more creative you are. Dr. Kenneth Heilman: 8:02 No Relationship. Now, it turns out that special talents are important. They’re very, very important. But of course, the IQ test doesn’t test special talents. So way back in the 1700s, there was a philosopher, Gall, who was actually the founder of phrenology, but Gall had two very important postulates. One postulate was that different parts of the brain perform different actions. And the second postulate was the better developed this module was, or this specific form better develop better at work. Now, what happened was Gall, was aware that our skull grew depends upon brain growth, so we said, oh, if we measured the skull, maybe we can tell about people and what they are capable of doing. The problem with that is it became a pseudoscience and all these people were making all these crazy suggestions, but it turns out a neurologist in France in the mid- 1800s, Paul Roca, heard a student of Gall’s talking about the importance for the frontal lobes and speech and he had a patient in the hospital who had a stroke sometime before was actually dying of, I think, tetanus and the patient had trouble speaking. He could understand, but he couldn’t get out the speech. The patient died and sure enough, he had a lesion in his frontal lobe. And then, in the second paper, Paul Broca examined eight people who had problems with speech from strokes, all eight of them, they were right-handed and all eight of them had left hemisphere strokes. So that provided a positive finding that really in some way, supported Gall’s, hypothesis. And we know that the left hemisphere understands speech. One of my mentors or Norman, Geschwind looked at a huge amount of people’s brains at the auditory cortex in the left hemisphere and the right hemisphere. And he found that the auditory cortex was actually bigger in most people in the left hemisphere, but even with great geniuses, sometimes their brains are different, but this hasn’t really been evaluated today. Richard Miles: 10:16 I just wanted to interject or ask a question about the role of the left hemisphere and at least the theory and how that contributes to creativity. Cause I remember in your book, which came out in 2010, it came out. I remember you described a number of what to me were surprising associations with higher creativity, including, for instance, being lefthanded, epilepsy, having dyslexia, being slow, and learning to speak, mental illness. And if I understood correctly, the general theory sort of connecting those was a suppression of, or damage to the left hemisphere actually allowed the right hemisphere of the brain more license, I guess and that may contribute to creativity. Dr. Kenneth Heilman: 10:57 You’re jumping ahead a little bit. Okay. There have been studies for example, by Miller who’s out in San Francisco, he looked at some people who had a degenerative disease, which mainly occurred in her left hemisphere and their artistic skills actually became enhanced and what was interesting, there hasn’t been a lot of research looking at the true geniuses, but one of the interesting stories about Einstein’s brain, it turns out that Einstein said it would be okay if they took his brain out and they examined it. And he was in Princeton, New Jersey, and there was a pathologist whose name was Thomas Harvey. So Harvey took the brain out and after it was fixated, he took a knife and he cut it into small blocks, 240 little blocks, and sent it all around the world to different people. And he said, well, tell me why he was a genius. People said, wait a minute, you gave me this little block of brain, how can I do anything? Well, the only thing that Harvey did was good was he actually photographed Einstein’s brain after he took it out. And what was really interesting is that on the left hemisphere, there’s a big, big, Valley called Sylvian fissure . It’s a big Fissure and it separates the frontal lobe from the temporal lobe and the parietal lobe from the temporal lobe. And what was really interesting about Einstein’s brain is that his Sylvian fissure can go all the way back and it didn’t actually go into the prior lobe . On the left side, it stopped really, really early. And after seeing that people said, oh, that’s why he was a genius because he didn’t have these big a soul . So I go into his prior lobe and dividing up his neural networks. Well, it turns out that one of the things we know about evolution is that the more GRI and salsa you have, it means the more cortex you have, okay. And that’s not a sign of superiority, it’s a sign that something is wrong. And if you look at his history, that part of the brain is very important for language I’m his parents for them to the pediatrician when he was about three years old, because he was not talking. And the other thing that was really interesting about Einstein’s brain, if you look at it, is that his right pro lobe was huge. Now, in addition, Arnstein was also probably dyslexic again, that parietal lobes’ important. So the question comes up that his less evolved left temporal low , allow his right to actually be superior. And it turns out when you read all the Weinstein’s works about himself, he said he always used spatial reasoning. And could it be that he was such a genius because again, his left hemisphere did not develop, but his right hemisphere really alone . Now, what’s really important. Also, as we’re going to talk about the frontal lobes are very important for divergent thinking. And it turns out, as I mentioned, Einstein had a huge, huge right frontal lobe. Richard Miles: 14:20 Ken, when we talk about divergent and convergent thinking for listeners who aren’t exactly sure what we mean by that, convergent thinking is when there’s one or a couple of right answers and you’re honing in on that right answer to a given problem and divergent thinking is when there could be a range of different types of solutions to a problem. One sort of looking in the other one sorta looking out. Dr. Kenneth Heilman: 14:41 Let me talk a little bit about that because the very first step in innovation to creative process is disengagement. What do I mean by disengagement? You have say, hey, this doesn’t explain your work, this is not the truth. And maybe one of the best examples of this is Copernicus who said , hey, wait a minute, this doesn’t make sense that will all revolving around the earth. Okay, It has to be other possibilities. Could it be that we’re revolving around Mars? or the sun? And then after he disengaged from that, he went ahead and used divergent thinking other possibilities, and he came up with a concept, hey, it’s the sun. We’re revolving around the sun. So the first step in creativity is first of all, disengagement, I don’t believe that’s the way done. Maybe as a better explanation. No one’s ever painted this one. No one’s ever written music. Hey, here’s a good novel no one’s ever written about. So you disengage from what has been done and then from there, you do divergent thinking saying, hey, what are the alternatives? What are the possibilities? Now it turns out from the neurological perspective, one of my mentors, Derek Denny Brown, brain neurologist said that all animals can do two things. They can approach or they can avoid and he said, this is even true of humans. He said it turns out that the frontal lobes are the disengage void organ and the temporal and parietal lobes and several or more for approach. And we know that when people damage their frontal lobes , what they do is they separate. In other words, they can’t disengage. So if we give them a test where they have to organize cards in a certain way called the Wisconsin card sorting , once they get one successful one, that’s it they’ll keep on repeating it, repeating it, repeating it, something we call the separation. And one of the things that we use to look at divergent thinking is something we call the alternative uses test. What you say to the person, okay, I’m going to give you an object and what I want you to do is give me the different things that you can do with this object. But the more different it is, the more points you get. So for example, I give somebody a word, the brick, if they say, Oh, you use it to build houses, to build fireplaces, you get maybe a point for each of those. If you say, Oh, you know, you’ve been using it as a doorstop or a bookend you get two points. If you say, Oh, you know, what you can do is take it in the bathtub with you and after your bath, you can use it to rub off your calluses you get three points. So your idea is that’s a test of divergent thinking, but creativity. So a lot of tests of creativity are one that’s used a lot is called a Torrance test. Where they have both verbal and visual-spatial test of divergent thinking. But as I said, this is only the first sub-stage of innovation. Now, a very important thing about innovation and creativity is curiosity and risk-taking. And that’s very, very, very important. And the reason why so many people get into creative occupations is because to them, it’s very rewarding. So you go back and you go through history and you look at artists , composers, whenever even scientists and what happened was financially, they did terribly, but they wanted to create because it gave them great joy. And the best example is Galileo, who proved Copernicus thing. You know, what the Pope did to him? Prisoner the rest of his life. Richard Miles: 18:36 Yeah. Dr. Kenneth Heilman: 18:36 And it turns out they finally forgave him about 40 years ago because he showed that the sun was in the center of the universe. Now it turns out that there’s a place deep in brain called the ventral striatum. And in animals, if you stimulate that, the animal will keep on doing whatever it was doing. It’s very rewarding. And that whole system is reward system. And it’s also hooked up to the frontal lobe. And it turns out that excitability of that system is very important for the drive and motivation. It turns out that, that system was also abnormal in people who use drugs. And that’s why actually, you see your very high rate of drug abuse in people who do creative. So let me go to the third part of innovation. So we have to disengage and say, hey, it has to be better answer to divergent thinking in saying , hey, what is the possibilities create ? The next one, and the critical element is finding the thread that unites and William James was really one of the founders of current psychology and said the thread that unites unheard of, combinations of elements and subtle associations and spearmint, another famous person who said creative ideas result from the combination of ideas that have been previously isolated. And perhaps the best example is Einstein’s E equals MC squared. Prior to that time, they were isolated. So it’s very important in the creative mode that the neurons in the brain and these modules that we’re talking about, that they communicate with each other. And there’s some evidence that that’s true. So one of the great experiments showing about this communication was done by a neurosurgeon, Joe Bogan. And we talked about that the right hemisphere is important for visual-spatial and the left for verbal and we had an epileptic’s whose seizures can be controlled, so they spread from one hemisphere to the other. So they were going to cut the connection between the two hemispheres, the corpus callosum. So the seizures couldn’t go from one side to the other side, but Bogan was curious whether or not this would interfere with creativity. So they gave people the inkblot test and the inkblot tests , as you know, just has inkblots and you tell people, hey, what does this look like? And then you could judge the creativity. People like me say that looks like a moth that looks like a bat and a lot of people come up with very creative ideas. So he tested these people and then after the collosum was cut, they retested them. And the creativity was actually gone. Why? Because the visual system could not communicate with the verbal system makes sense? Richard Miles: 21:31 These various parts of the brain have to be constantly swapping information with each other. Dr. Kenneth Heilman: 21:35 And in fact, when you record from the brain, the brain waves, when people are in a creative mode, their brainwaves actually go ahead and have a certain type of coherence, like they’re all communicating with each other. So in general, one of the things we ask is how do we increase our networks? Well, one of the great stories about chemistry is about tequila. They knew benzene had six carbons, but they didn’t know how it was organized. So he was drowsy and off to sleep. When you imagine or dream about a snake, biting its own tail in gear , Hey, it’s a ring, but it turns out if you look at almost all great creative ideas, people were almost always in a state of relaxation. Isaac Newton, when he came up with calculus and he came up with the laws of gravity, there was an epidemic almost like ours , but I think it was a little bit worse and they closed up Cambridge university. It was a plague, and so, he went up to his mother’s farm and now we have plenty of time and he sat under the apple tree and thought about these problems and came up with these ideas. When he went back to Cambridge, after it was over, they gave all kinds of administrative jobs because she was so successful with the ideas, he didn’t come up with much after that. Einstein came up with most of his theories late at night, in the patent office, when it was very, very quiet. Even when you think about when you get a great idea, you yell Eureka! Well, it was Archimedes who came up with that idea, the concept of buoyancy and what was he doing? He was taking a bath, another relaxing thing. The person who actually improves the nerves theory of the brain was a spanish physician, Raymond Ecohall, and he wrote a book actually, about creativity, which is an interesting book. In the book he says, if a solution fails to appear yet, we feel success is around the corner, just try resting for awhile . Now, another thing that we know about creativity is actually that one of the most creative types of people are people who have depression and bipolar disorder tend to be very, very creative. And so we thought what’s going on here about sleep, relaxation, depression, all those kinds of things. Well, it turns out they’re all similar in that in our brain, we have a neurotransmitter called norepinephrine. And when you get norepinephrine what happens is your attention goes externally rather than internally. So for example, if you were a child and you were sitting in the back of your class, just dreaming, daydreaming all the time the teacher you would say, hey, take your son or daughter to the doctor and get em some medicine. They give medicines like Dexedrine. They increase no norepinephrine. What do people do then? They attend to the teacher, they don’t go into their own mind . If you’re going to be creative, guess what you have to do. What do depressant people do almost all day long? Go into their own mind . So we actually wanted to test that theory. I did this with a fellow David B. We gave normal participants, anagram tests . You take words and you mix up the letters and you see how long it takes them to get the word. And some of them, we gave a medication called Propranolol, it blocks norepinephrine . One of the bad side effects, it turns out, if people take it too long, is depression. And it turns out when we gave these people Propranolol, this beta blocker of norepinephrine, guess what? They performed much better. Then with another fellow George Gotcebing. We know that when we treated epileptics, we found that one of the ways of doing it is by simulating one of the cranial nerves called the Vegas nerve. And what the Vegas nerve does is actually increase the output of norepinephrine in the brain. And it’s interesting because now they also use it to treat depression and we gave creativity tests while we’re stimulating. And we weren’t stimulating and low and behold, what do we find out? That when we are stimulating him your creativity went down. So in general, it’s important to go ahead and be in a very relaxed state. Richard Miles: 26:07 It sounds like in general, there’s this obviously complex interplay between left and right hemisphere and various areas of the brain. But if I had to sum it up, it seems to me in your book, a part of what you do is say that these various conditions in left hemisphere, whether they’re through an accident of birth, or an injury, or a certain mental state, we’re in the inclination to search for that conversion type of thinking and free up, the more divergent type of thinking that may occur elsewhere in the brain. Who , for instance, like I’d signed that the example you gave of him being delayed in his speaking clearly didn’t make him not a creative person. It may been just the opposite. Dr. Kenneth Heilman: 26:44 This is important that when people get head injuries, the place that they injure most likely is the, frontal lobes and the connections. And the frontal lobes are the critical thing, both for divergent thinking and for motivation to continue working and to actually produce the creative object or thought or whatever it might be. So, no , that’s not generally true. There have been cases where people did get injured. Strokes, dementia that didn’t enhance the creativity, but remember in those people, they paid a price, they were disabled. So yes, in certain unusual cases, brain damage can enhance it. But in most people interferes with every stage, the first stage, the preparation it interferes with that, it interferes with divergent thinking and it also interferes with convergent thinking. Richard Miles: 27:36 Ken, if we could come back to the question earlier, how much of this is hardwired? And you’re basically born with this ability to do that creative type of thinking at a high level and how much of it could be taught in schools or taught in workplaces and people could sort of make themselves be more creative in general? Dr. Kenneth Heilman: 27:53 No, you’re asking a very, very important question that’s going on for centuries and centuries. In general, both are important. Nature is important. Brain development is important and nurture is important. And those two things have to go together. So for example, there’s the famous story in Romania. The leader during communist times wanted to increase the population. So we encouraged people to have more and more children and they couldn’t afford the children, so they put them into these units. They fed them, but they didn’t play with them, and they didn’t hug them. Guess what’s happened to these kids. They were all mentally impaired because they need that stimulation to have the brain growth. And this is true throughout life. So it’s not purely nature because nurture helps develop the brain. And that’s been shown, you need a combination of both, but I think it is very, very important growing up to be a stimulator as possible and to do as many new and novel things that possibly you can. One of the things that really troubles me about our educational system is that in general, they downplay the opportunity for children to be creative. So who are the first teachers they fire when you have economic problems? Richard Miles: 29:12 The music teacher and those folks, right? Dr. Kenneth Heilman: 29:14 The music teacher and the art teacher, And in general, how do they gauge how well somebody does, they gauge it by their knowledge. There’s no tests that they give em that really looks at their creativity. And none of the teachers in school talk about even how do we enhance this creativity? And it’s really a shame because it turns out there was a book written by Richard Florida, and in his book, he says something very, very, important which is coming to be true in the future. The success of different nations, societies is not going to be based on people’s labor, like labor in factories, and so forth. It’s going to be primarily based on creativity. America has been very, very fortunate because it was a country of immigration. And the people who came here said, Hey, wait, I don’t like what things are going on here, there must be a better way. And therefore, America has been a very creative country. My grandmother, who was a Jewish grew up in Belarus, was pregnant with my mother and she told her husband, I don’t want to bring my kids up here. It can be spiteful and treated badly, I want to go to America. And it turns out that America allows people to become very creative. But we need to really force that in our school systems and we’re not doing it. And we’re doing everything the opposite way. So for example, in medicine now, how did they decide how valuable you are? By how many relative value units. So I’ll just tell you the story about me very briefly. I see patients with cognitive disorders and usually, in my afternoon clinic, I would see about four patients, but I was teaching medical students. And most of these patients were sent by other neurologists because they couldn’t figure out what was going on with these patients. And if you go into pub med and type my name, you’ll see how many reports there are about unusual patients. I got a letter from an administrator at The University of Florida that said, you come to clinic at 12:30, you don’t leave clinic until past six o’clock, and you’ll only see four new patients. It wasn’t really his fault, that is the mentality now. So even medicine, if you see something interesting, something that’s different that you want to really look at and examine you can’t do it. So, and so many domains were interfering in the schools and medical schools were interfering with really the growth of creativity. Which takes time, rest and patience. Richard Miles: 31:56 We’ll Ken, thank you very much. We’re about out of time, but that’s been a fascinating discussion about the relationship of creativity and the brain. And I’m thankful that somebody invented the internet and zoom and laptops, those creative folks made this conversation possible. So thank you to that wider community who makes these conversations as possible, but thank you very much for joining us today on Radio Cade. Dr. Kenneth Heilman: 32:17 Thank you for inviting me and for all the wonderful work you all are doing in enhancing creativity to Bob Cade is so wonderful. Finding out about the museum is something that’s looking at attempting to enhance creativity. Thank you so much. Richard Miles: 32:32 Well, thanks for coming on Ken, appreciate it. Outro: 32:34 Radio Cade is produced by the Cade museum for Creativity and Invention in Gainesville, Florida . Richard Miles is the podcast host and Ellie Thom coordinates, inventor interviews. Podcasts are recorded at Hardwood Soundstage, and edited and mixed by Bob McPeak . The Radio Cade theme song is produced and performed by Tracy Collins and features violinist, Jacob Lawson.

Project Love - Für Singles
039 | Mehr Fülle im Leben – Interview mit Alice Geschwind

Project Love - Für Singles

Play Episode Listen Later Apr 16, 2020 23:22


In dieser Folge spreche ich mit Alice über ein erfülltes und glückliches Leben unter anderem auch im Single-Leben. Dabei verrät sie uns ihre Erkenntnisse und gibt konkrete Tipps an die Hand, die Du selbst für Dich gut umsetzen kannst. Viel Spaß beim Anhören Deine Maria _____________ Hier findest Du Alice: Instagram: https://www.instagram.com/alice_geschwind/ Webseite: https://herzensbox.de/ E-Mail: info@herzensbox.de _____________ Titelmusik: Gemafreie Musik von www.frametraxx.de

Kino+
Das persönliche Spezial mit Daniel, Ede, Antje und Wolfgang M. Schmitt

Kino+

Play Episode Listen Later Mar 5, 2020 89:26


Da saß es nun, das Kino-Plus-Team, bereit, ein neues Spezial zum Thema New Hollywood aufzuzeichnen. Und dann fehlte plötzlich ein Teil der Besetzung. Geschwind wurde jedoch aus der Not eine Tugend gemacht. Wolltet ihr nicht schon immer mal wissen, wie Daniel, Eddy, Antje und Wolfgang eigentlich zum Thema Film gekommen sind? In diesem ganz speziellen Spezial soll es um die privaten Anfänger eurer Lieblings-Filmnerds gehen. Um stundenlange Besuche in Videotheken, Lieblingsfilme, aufregende Kinoerlebnisse und alles, was euch die vier bislang noch nicht bei Kino Plus verraten haben. Also lehnt euch zurück und genießt dieses ganz spezielle Kino-Plus-Spezial aus den heiligen Rocket-Beans-Hallen. Danach werdet ihr uns (vielleicht) mit anderen Augen sehen...

Next Generation Football
Chelsea v Ajax UCL combined 11 FT: Marc Geschwind

Next Generation Football

Play Episode Listen Later Nov 5, 2019 41:38


Previewing the Chelsea v Ajax game, plus a combined 11 of the Ajax & Chelsea squad with EIFsoccer admin Marc Geschwind. Make sure to go follow Marc on Twitter @MarcGeschwind

PositivePsychology.com Podcast
#6 - Nicole Geschwind on Positive CBT

PositivePsychology.com Podcast

Play Episode Listen Later Oct 2, 2019 51:06


In this episode on the PositivePsychology.com podcast, Hugo talks with Positive CBT expert and researcher Nicole Geschwind. Nicole has some really interesting insights to share on positive emotions and mindfulness, as well as practical strategies for applying Positive CBT.Support the show (https://positivepsychology.com/toolkit/)

The Daily Gardener
August 29, 2019 Remaking Containers, The Botanists Patrick Browne, Rudolf Geschwind and the Countess of Roses, Christina Rossetti, Colors from Nature by Bobbi McRae, Redesigning with Hostas, and Ingrid Bergman in Cactus Flower

The Daily Gardener

Play Episode Listen Later Aug 29, 2019 13:16


Well, it's time to get serious about remaking our containers – especially on the front porch and around the front door.   Editing containers from time to time is essential to keep them looking great.   Sometimes combinations don’t work well, other times plants can grow in unexpected ways – too tall, too bushy, or just an abject failure.    With the arrival of fall, it’s the perfect time to remove spent plants and replace them with selections that are more seasonally appropriate.   Fall pansies are wonderful to incorporate if you live in a cold climate. They can take the colder temperatures with no problem. Of course mums and asters and even grasses are wonderful in fall pots.   I always like to look for bargains at my local nurseries and big box stores. Sometimes those finds get placed in containers temporarily before they find a home in the garden.   And don’t forget you can include houseplants when you’re working with your fall containers. Pathos and Croton, even chopped up sections from an overgrown Boston fern are tremendous additions to fall containers.     Brevities #OTD Today is the anniversary of the death of the Irish botanist and friend of Linnaeus, Patrick Browne who died on this day in 1790.  There are no photographs of Patrick Browne - who was also a physician; but we was described this way: “The Doctor is a tall comely man, of good address and gentle manners, naturally cheerful, very temperate and in general health.” Browne's major work was The Civil and Natural History of Jamaicapublished in 1756 in which he described 104 new species. In fact, Browne's work was the first book in the English language to use Linnaeus' classification system. Linnaeus was very pleased with Browne's work. He told the botanist Peter Collinson (who was friends with John Bartram and Benjamin Franklin) that after he had read Browne's book he reflected “No author did I ever quit more instructed" and he gushed that Browne, "ought to be honored with a Golden Statue.” Browne named the genus to which cloves belong: Syzygium aromaticum.      #OTD   Today is the birthday of the German Austrian rosarian Rudolf Geschwind who was born on this day in 1829. As a child, Geschwind loved gardening. As a young man, he studied Forestry and his first job was working for the Austro-Hungarian Department of Forestry. Although he performed excellent work in the field of forestry, Geschwind's true passion was roses. At the age of 30, Geschwind began experimenting with breeding roses.  It was a pursuit he would perfect over the next five decades. Geschwind's speciality was breeding roses that were frost resistant. Geschwind created close to 150 rose cultivars. His prized collection of climbing roses were displayed at the 1889 World's Fair in Paris. When Geschwind died in 1910, the Countess Maria-Henrieta Chotek, known as "The Countess of Roses,"  or "The Pink Countess," purchased Geschwind's entire collection - including some which had never been made public. As a member of one of the most distinguished families of the Czech nobility, Chotek had the means to handle this impressive transfer. In fact, Chotek was so serious about the effort to preserve Geschwind's work that she sent two of her gardeners to oversee the transfer of the collection. It was no small affair - it involved packing and moving over 2,000 roses to her estate - the Manor House or Castle known as Dolna Krupa. Over a century before Dolna Krupa was the place where Beethoven is presumed to have written his Moonlight Sonata. Maria-Henrieta's great grandfather, Jozef, was friends with Beethoven and he allowed Beethoven to live at Dolna Krupa for nearly a decade. Maria-Henrieta Chotek was born almost 60 years after Beethoven's stay at Dolna Krupa in 1863. As a woman who never married, her inheritance allowed her to pursue her passion for roses with abandon - and she did. She was in her 30's when she inherited Dolna Krupa. Once it was all hers, she set about creating one of the top three rosaria in Europe. During its prime, the rosaria at Dolna Krupa rivaled the roseria in France and the Rosarium of Sangerhausen in Germany. Chotek was a woman of action and she didn't just direct activities - she was very hands on. As a rosarian herself, Chotek developed new cultivars and conducted experiments. One time while visiting an exhibition, Chotek watched as a German horticulturist named Johannes Böttner presented a rambling rose called the Fragezeichen which means the "Question Mark" (What a great name!) The rose intrigued Henrieta Chotek so much, that she immediately left for Frankfurt to see the Fragezeichen trials personally. The year 1914 marked a turning point in Chotek's life and in the fate of many of Geschwind's roses. That year, in June, the Rose Congress was held at Zweibrücken. Chotek's work and rosaria were honored. But in the days following the event, Marie Henrieta's cousin, Sophie Chotek Ferdinand, wife of the Archduke Franz Ferdinand, was murdered alongside her husband in Saraevo and World War I had begun. Chotek swung in to action; this time as nurse caring for wounded soldiers. When the war was over, her rosarium was destroyed. Chotek immediately set about rebuilding her rosarium. She even began a rose breeding school right on the grounds pf Dolna Krupa. But, lacking the means and the energy of youth, Chotek was never able to restore Dolna Krupa to its former glory. During WWII, Dolna Krupa was ransacked by the Russian Army. In February, 1946, destitute and sick, Chotek died while in the care of nuns. She was 83 years old. Today, the Music Museum at Dolna Krupa holds a Rose Celebration in honor of Chotek. Tourists visit Dolna Krupa, primarily to see the place Beethoven lived. Visitors bring their own baskets and collect leaves of the wild garlic that grows rampant on the grounds of the estate.         Unearthed Words Here's an excerpt from a poem called A Year's Windfallsby the English poet, Christina Rossetti: "In the parching August wind,  Cornfields bow the head,  Sheltered in round valley depths,  On low hills outspread.  Early leaves drop loitering down Weightless on the breeze,  First-fruits of the year's decay  From the withering trees."  Christina Rossetti wrote the words to two of my favorite Christmas Carols: "In the Bleak Midwinter" and "Love Came Down at Christmas". It was Christina Rossetti who said, "My garden cannot be anything other than "my self."     Today's book recommendation: Colors from Nature by Bobbi McRae Colors from Nature was published in 1993. McRae shares how to grow plants to collect, prepare and use natural dyes.   Today's Garden Chore Now's the perfect time to relocate your hostas to improve the aesthetic of your garden. It's hard to know sometimes when you plant a hosta how you will feel about it once it's matured. When they are little, we often place hostas in a haphazard fashion - here's an empty spot - let's stick a hosta there. If you're not careful, the garden can end up looking like the hosta version of a patchwork quilt. And while you're placing them, remember that your blue or darker hostas like more shade - while the lighter colors of the yellowy green hostas and variegated hostas can take more sun.     Something Sweet  Reviving the little botanic spark in your heart #OTD On this day in 1915 Ingrid Bergman, the actress, was born in Stockholm, Sweden. (She also died on the same day in 1982 at the age of 67.) Bergman appeared in a number of films including the iconic Casablanca. In 1969, Bergman appeared in a movie called Cactus Flower. Bergman was portraying a nurse named Stephanie Dickinson working in a Dentist's office. The dentist was played by Walter Matthau. Gardeners adore the movie Cactus Flower for the following lines read by Bergman: Early in the film Bergman is talking to Matthau and she puts him in his place by saying, "Doctor, you once compared me to my cactus plant. Well, every so often, that prickly little thing puts out a flower." Then, later in the film she memorably exclaims, "My cactus! It's blooming!"     Thanks for listening to the daily gardener, and remember: "For a happy, healthy life, garden every day."

Kerkerkumpels (Pen&Paper)
Begegnung an der Großen Gleichheit [S01|E03]

Kerkerkumpels (Pen&Paper)

Play Episode Listen Later May 21, 2019 41:35


Nachdem unser dynamisches Trio die widerspenstige Ria aus dem orkischen Sex-Dungeon befreit hat, ist guter Rat teuer – denn der „Cirque du Cachot“ ist ohne sie abgereist! Geschwind machen Gustl, Brielle, Ria und Zlotan sich also eigenständig auf den Weg nach Blutstadt; ihr weg führt sie an der mysteriösen „Großen Gleichheit“ vorbei, wo sie eine spannende Bekanntschaft machen. Und was hat das alles mit Griesbrei zu tun? Findet es in dieser Folge heraus!“ Du hörst die Kerkerkumpels, einen Pen & Paper Podcast. Die Geschichte, die du hörst, ist live improvisiert und ungeschnitten. Nur Soundeffekte wurden im Anschluss hinzugefügt, um ein immersives Hörspielerlebnis zu erschaffen. Sound- & Musikquellen: „Circus Tent“ Kevin MacLeod (incompetech.com)Licensed under Creative Commons: By Attribution 3.0 Licensehttp://creativecommons.org/licenses/by/3.0/

Medical Research Mongol Podcast
2. Cesarean section and gut microbiome

Medical Research Mongol Podcast

Play Episode Listen Later Nov 9, 2017 12:34


Монголчуудын хэлж заншсанаар "хийсвэр хагалгаа"-гаар төрсөн хүүхэд эхээс үрд дамжих бактериудын нөлөөгөөр хэрхэн өөрчлөгдөж болох вэ гэдгийг ярилцна. Судалгааны дэлгэрэнгүйг: Sharon, G., Sampson, T. R., Geschwind, D. H., & Mazmanian, S. K. (2016). The central nervous system and the gut microbiome. Cell, 167(4), 915-932.

Medical Research Mongol Podcast
2. Cesarean section and gut microbiome

Medical Research Mongol Podcast

Play Episode Listen Later Nov 8, 2017 12:34


Монголчуудын хэлж заншсанаар "хийсвэр хагалгаа"-гаар төрсөн хүүхэд эхээс үрд дамжих бактериудын нөлөөгөөр хэрхэн өөрчлөгдөж болох вэ гэдгийг ярилцна. Судалгааны дэлгэрэнгүйг: Sharon, G., Sampson, T. R., Geschwind, D. H., & Mazmanian, S. K. (2016). The central nervous system and the gut microbiome. Cell, 167(4), 915-932.

Génération jeunes interprétes
L'Académie Philippe Jaroussky ; Nathalia Milstein ; Philibert Perrine et Guillaume Sigier

Génération jeunes interprétes

Play Episode Listen Later Oct 7, 2017 118:29


durée : 01:58:29 - L'Académie Philippe Jaroussky ; Nathalia Milstein ; Philibert Perrine et Guillaume Sigier - par : Gaëlle Le Gallic - **[Philippe Jaroussky](http://www.philippejaroussky.fr/) et des élèves de l’[Académie Philippe Jaroussky](http://academiejaroussky.org/) à la Seine musicale Clarisse Dalles, soprano Célia Onéto-Bensaïd, piano Sarah Jégou, violon Jérémy Garbarg, violoncelle Vincent Mussat, piano** {% image 3e5021ec-229c-4873-8563-d70e9414de3b %} **[Nathalia Milstein](http://nathaliamilstein.com/fr/biography.html), piano** **[Philibert Perrine](https://www.facebook.com/philibert.perrine), hautbois [Guillaume Sigier](http://www.guillaumesigier.fr/actualites), piano** ## Programme musical **Ludwig van Beethoven** _Sonate n° 28 en la majeur op. 101 I. Etwas lebhaft, und mit der inngsten Empfindung. Allegretto, ma non troppo II. Lebhaft. Marschmäßig. Vivace alla Marcia III. Langsam und sehnsuchtsvoll. Adagio, ma non troppo, con affetto IV. Geschwind, doch nicht zu sehr und mit Entschlossenheit. Allegro_ Nathalia Milstein **Frédéric Chopin** _Trois Mazurkas op. 63 I. Mazurka n° 39 en si majeur : Vivace II. Mazurka n° 40 en fa mineur : Lento III. Mazurka n° 41 en ut dièse mineur : Allegretto_ Nathalia Milstein {% image 37b258d3-6671-42c8-bc8b-9c044469e109 %} **Emmanuel Chabrier** _Six Mélodies, VI : L'Île heureuse_ Clarisse Dalles et Célia Onéto-Bensaïd **Francis Poulenc** _Priez pour la paix_ Clarisse Dalles et Célia Onéto-Bensaïd **Gabriel Fauré** _Prison op. 83 n° 1_ Clarisse Dalles et Célia Onéto-Bensaïd **Max Bruch** _Concerto pour violon n° 1 en sol mineur op. 26 : II. Adagio_ Sarah Jégou et Vincent Mussat **Robert Schumann** _3 Fantasiestücke op. 73_ _I. Zart und mit Ausdruck / II. Lebhaft, leicht / III. Rasch und mit Feuer_ Jérémy Garbarg et Vincent Mussat **Clara Schumann** _Trois Romances op. 22 I. Andante molto / II. Allegretto / III. Leidenschaftlich schnell_ Philibert Perrine et Guillaume Sigier **Camille Saint-Saëns** _Sonate pour hautbois avec accompagnement de piano en ré majeur op. 166 I. Andantino / II. Allegretto / III. Molto allegro_ Philibert Perrine et Guillaume Sigier **Amilcare Ponchielli** _Capriccio pour hautbois et piano_ Philibert Perrine et Guillaume Sigier ## Dans la cour des grands **[Monte-Carlo Voice Masters 2017](http://www.montecarlomusicmasters.com/voice/) Du 11 au 15 octobre Génération jeunes interprètes recevra le lauréat ou la lauréate** ## Agenda **Vivaldi-Piazzolla, Saisons : d'un rivage à l'autre 7 et 14 octobre[ Le Concert idéal](http://www.leconcertideal.com/)** **[Jeunes Talents](https://www.jeunes-talents.org/) : demandez le programme d'octobre !** ## Réseaux sociaux[](https://fr-fr.facebook.com/generationjeunesinterpretes/) [La page facebook du Fan club de Génération jeunes interprètes](https://fr-fr.facebook.com/generationjeunesinterpretes/) - réalisé par : Jean-Pierre Collard

古典音乐收割机
Sonata No.27 in E minor op.90 - II Nicht zu geschwind und sehr singbar vorzutrag

古典音乐收割机

Play Episode Listen Later Oct 29, 2016 7:56


音乐是财富是一种心情、是一个改变自己的方式。 它能表达出你的心情,释放你的压力,找到你的共鸣!

古典音乐收割机
Sonata No.28 in A major op.101 - III Langsam und sehnsuchtsvoll – Geschwind doc

古典音乐收割机

Play Episode Listen Later Oct 29, 2016 10:21


音乐是财富是一种心情、是一个改变自己的方式。 它能表达出你的心情,释放你的压力,找到你的共鸣!

Höflichkeit, Respekt, Etikette, Stil

Abhandlung über das Thema Gesittetheit. Simple und komplexe Gedankengänge zum Thema Gesittetheit in diesem kurzen Vortrag. Sukadev behandelt hier dieses Thema aus dem Geist des ganzheitlichen Yoga. Es gilt, alles mit Liebe zu betrachten. Ähnliche Begriffe sind z.B. Gespräch, Gestaltlos, Gewalt, Gewaltsamkeit, Gesichtsausdruck, Geschwind, Geschrei.

Innere Unruhe, Rastlosigkeit und Getriebenheit überwinden

Abhandlung über das Thema Gesittetheit. Simple und komplexe Gedankengänge zum Thema Gesittetheit in diesem kurzen Vortrag. Sukadev behandelt hier dieses Thema aus dem Geist des ganzheitlichen Yoga. Es gilt, alles mit Liebe zu betrachten. Ähnliche Begriffe sind z.B. Gespräch, Gestaltlos, Gewalt, Gewaltsamkeit, Gesichtsausdruck, Geschwind, Geschrei.

EiF Soccer
EIF August 5 Liverpool Preview

EiF Soccer

Play Episode Listen Later Aug 5, 2015 3:32


In the fifteenth installment of the EIF team previews, Marc "Van der" Geschwind previews Liverpool's upcoming season. Can they finally survive the loss of Suarez a year later?

CARTA - Center for Academic Research and Training in Anthropogeny (Audio)
CARTA: Human Origins: Lessons from Autism Spectrum Disorders - Daniel Geschwind: Systems Biology of Autism Spectrum Disorders

CARTA - Center for Academic Research and Training in Anthropogeny (Audio)

Play Episode Listen Later Jan 18, 2013 18:40


Daniel Geschwind (UCLA) and his colleagues have been working to identify autism risk genes and understand how these might lead to autism spectrum disorders (ASD). Many genes with distinct functions have been identified as ASD susceptibility genes. In this lecture, he indicates how systems biology approaches demonstrate that pathways necessary for normal brain development and function are altered in ASD. Identification of these pathways is the first step toward developing treatments of ASD. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 24823]

CARTA - Center for Academic Research and Training in Anthropogeny (Video)
CARTA: Human Origins: Lessons from Autism Spectrum Disorders - Daniel Geschwind: Systems Biology of Autism Spectrum Disorders

CARTA - Center for Academic Research and Training in Anthropogeny (Video)

Play Episode Listen Later Jan 18, 2013 18:40


Daniel Geschwind (UCLA) and his colleagues have been working to identify autism risk genes and understand how these might lead to autism spectrum disorders (ASD). Many genes with distinct functions have been identified as ASD susceptibility genes. In this lecture, he indicates how systems biology approaches demonstrate that pathways necessary for normal brain development and function are altered in ASD. Identification of these pathways is the first step toward developing treatments of ASD. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 24823]

CARTA - Center for Academic Research and Training in Anthropogeny (Audio)
CARTA: Human Origins: Lessons from Autism Spectrum Disorders – The Evolutionary Biology of Autism Risk Systems Biology of Autism Spectrum Disorders and The Fetal Androgen Theory

CARTA - Center for Academic Research and Training in Anthropogeny (Audio)

Play Episode Listen Later Dec 19, 2012 57:50


This fascinating and important series from CARTA explores the newest understandings of the roots of autism disorders from the foremost researchers in the world. In this episode, UCLA’s Daniel Geschwind, Simon Fraser University’s Bernard Crespi and Cambridge University’s Simon Baron-Cohen discuss The Evolutionary Biology of Autism Risk, Systems Biology of Autism Spectrum Disorders, and The Fetal Androgen Theory Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 24456]

CARTA - Center for Academic Research and Training in Anthropogeny (Video)
CARTA: Human Origins: Lessons from Autism Spectrum Disorders – The Evolutionary Biology of Autism Risk Systems Biology of Autism Spectrum Disorders and The Fetal Androgen Theory

CARTA - Center for Academic Research and Training in Anthropogeny (Video)

Play Episode Listen Later Dec 19, 2012 57:50


This fascinating and important series from CARTA explores the newest understandings of the roots of autism disorders from the foremost researchers in the world. In this episode, UCLA’s Daniel Geschwind, Simon Fraser University’s Bernard Crespi and Cambridge University’s Simon Baron-Cohen discuss The Evolutionary Biology of Autism Risk, Systems Biology of Autism Spectrum Disorders, and The Fetal Androgen Theory Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 24456]

Help 4 HD Live!
The HD Veiw with Dr. Michael Geschwind

Help 4 HD Live!

Play Episode Listen Later Apr 30, 2012 80:00


Monday, April 30, 2012 at 3:30 pm PST/6:30 pm EST Dr. Michael Geschwind is Associate Professor of Neurology and the Michael J. Homer Chair in Neurology. He received his MD and PhD in neuroscience through the National Institutes of Health-sponsored Medical Scientist Training Program at the Albert Einstein College of Medicine in New York. He completed his internship in internal medicine at the University of California, Los Angeles Medical Center, his neurology residency at the Johns Hopkins University School of Medicine in Baltimore and his fellowship in behavioral neurology at the UCSF Memory and Aging Center (MAC). He joined the Memory and Aging Center faculty in 2003 and is now an associate professor and holds the Michael J. Homer Chair in Neurology.  Dr. Geschwind's primary research interest is the assessment and treatment of rapidly progressive dementias, including prion diseases, such as Creutzfeldt-Jakob disease (CJD), autoimmune antibody-mediated dementias and encephalopathies.   He also has an active interest in movement disorders and cognition, including Progressive supranucelar palsy (PSP), corticobasal syndrome (CBS), and Huntington's disease (HD). He is an active member of the Huntington's Study Group.  Tune in for some interesting information. Visit his website: www.memory.ucsf.edu

American Journal of Psychiatry Audio

This audio program discusses a long-term study examining how the depressive state affects the assessment of personality disorder; the pharmacogenetics of antidepressant response; the association between depression and incident diabetes; how brain activity of patients with generalized anxiety disorder reacts to emotional conflict; and the neuropsychiatric aspects of lupus in a patient case that also involved erotomania and the Geschwind syndrome. Articles can be viewed online at www.ajp.psychiatryonline.org.

PaperPlayer biorxiv neuroscience
Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Jan 1, 1970


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.04.17.044222v1?rss=1 Authors: Li, J., Pan, L., Godoy, M. I., Pembroke, W. G., Rexach, J. E., Condro, M. C., Alvarado, A. G., Harteni, M., Chen, Y.-W., Stiles, L., Chen, A. Y., Wanner, I. B., Yang, X., Goldman, S. A., Geschwind, D. H., Kornblum, H. I., Zhang, Y. Abstract: Human-mouse differences are a major barrier in translational research. Astrocytes play important roles in neurological disorders such as stroke, injury, and neurodegeneration. However, the similarities and differences between human and mouse astrocytes are largely unknown. Combining analyses of acutely purified astrocytes, experiments using serum-free cultures of primary astrocytes, and xenografted chimeric mice, we found extensive conservation in astrocytic gene expression between human and mouse. However, genes involved in defense response and metabolism showed species differences. Human astrocytes exhibited greater susceptibility to oxidative stress than mouse astrocytes, due to differences in mitochondria physiology and detoxification pathways. Mouse astrocytes, but not human astrocytes, activate a molecular program for neural repair under hypoxia. Human astrocytes, but not mouse astrocytes, activate the antigen presentation pathway under inflammatory conditions. These species-dependent properties of astrocytes may contribute to differences between mouse models and human neurological and psychiatric disorders. Copy rights belong to original authors. Visit the link for more info