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// UPDATE ON LITTLE SUGAR GROUP RIDE //Saturday, Oct. 11 at 9:00am!Will leave from Finish Line for a 11.7mi route that covers the finish.Route: https://www.strava.com/routes/3411217966276238992
Today, I'm joined by the remarkable Dr. Vonda Wright, an orthopedic surgeon, elite sports doctor, and a passionate advocate for redefining how we age. Dr. Wright's philosophy goes far beyond the operating room—she believes that saving our mobility is truly what saves us from the ravages of chronic disease and a life of unnecessary pain. Fresh from the operating room and still in her scrubs, she sits down to share her mission: empowering women (and men!) with the knowledge and actionable habits that protect our strength, bones, and brains as we move through midlife and beyond. Episode Timestamps: Saving mobility to prevent chronic disease ... 00:07:17 Empowering women in healthcare decisions ... 00:09:04 Focusing on women's strength, aging, and research ... 00:11:23 Master athletes: mobility impact on aging bones and brain ...00:12:12 MRI evidence: active vs. sedentary muscle ... 00:15:51 Can seniors regain strength? Real-life transformation ... 00:19:54 Nutrition basics: protein, sugar, and inflammation ... 00:27:53 Critical decade: 35–45 and early warning signs ... 00:42:16 Hormone optimization and bone health ... 00:48:37 Dr. Vonda's personal menopause journey ... 00:52:08 Lifting, sprinting, and body recomposition ... 00:58:10 Fitness advice: women vs. men, VO2 max, and frailty ... 01:00:05 Rapid fire: exercise tips, nutrition, aging myths ... 01:05:41 Book announcement and key takeaways ... 01:09:09 Final thoughts: It's never too late ... 01:10:03 Our Amazing Sponsors: MitoLux Lite Sunlamp - UVB at 295 nm to naturally boost vitamin D, plus red light for collagen and infrared for recovery. Get 10% off your MitoLux Lite Sunlamp at https://mitolux.com/NAT10. NAT10 will be automatically applied at checkout. BEAM Minerals - Mineral deficiency support. One shot in the morning, tastes like water, and you've just restored every essential mineral your cells are craving. Go to beamminerals.com, use code NAT20, and get 20% off your first order. Nootropept by LVLUP - an advanced cognitive enhancement formula that combines fast-acting neuropeptides, cholinergic support, and mitochondrial-boosting compounds to sharpen mental clarity, memory, and long-term brain performance. Visit https://lvluphealth.com/ and use code NAT at checkout for 20% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
Is your smartwatch just a fun gadget, or a serious medical device? In this episode, Jonathan Wolf is joined by Dr. Malcolm Findlay, a leading consultant cardiologist, to explore the powerful health data available on your wrist. They decode the most misunderstood metric, Heart Rate Variability (HRV), and reveal how your wearable can provide clinical-grade insights into your heart's health. Dr. Findlay explains the counter-intuitive science behind HRV — why more ‘wobble' in your heartbeat is a sign of good health — and breaks down the two opposing nervous systems that control it. He shares the latest on how these devices can accurately detect serious conditions like atrial fibrillation and why he, as a cardiologist, trusts the ECG function on a consumer smartwatch to make diagnoses. For listeners who track their own data, this episode is a practical guide to what your numbers actually mean. Dr. Findlay explains how to interpret your personal HRV trends, what constitutes a significant change, and when you should use the ECG feature. He also debunks common myths about heart rate zones, revealing the level of exercise intensity that truly benefits your long-term health. The episode concludes with an empowering look at how this technology is shifting control into our own hands. Can a simple alert from your watch really help prevent a catastrophic event like a stroke? Discover which metrics matter most and how to use them to guide your wellness journey.
Think your breathing has little impact on performance? Adam shows how BioHarmonizing your breath with 5.5-second rhythms, CO2 tolerance, & HRV tracking can improve sleep, reduce stress, & raise endurance. Meet our guest Adam is a serial entrepreneur who, after selling Captify Technologies in 2021, became fascinated with the power of breath work. He studied under Patrick McKeown, the world's #1 functional breath work expert & now lead advisor at FivePointFive, a breath work app built to enhance mental & physical fitness while tracking results in real time. Thank you to our partners Outliyr Biohacker's Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Resonant frequency breath rates around 5.5 seconds in & out optimize nervous system balance & boost HRV Wearables & apps track markers like HRV & VO2 max, helping you personalize & monitor progress over time Breath work isn't one size fits all. Optimal rates & techniques shift based on your health, training, & daily needs HRV is more than daily changes. Look at trends over time & compare to your own baseline, not others Specific breath work improves oxygen use & increases VO2 max by up to 8–11% within weeks—huge for athletes Higher carbon dioxide tolerance trained with nose breathing & breath holds helps your body use oxygen more efficiently Slower longer exhales & relaxed breathing after exercise speed up recovery by up to 46%—faster performance gains Breathing through your nose especially in childhood shapes facial & dental structure & boosts immunity Intentional breathing is the quickest way to shift your nervous system within seconds you reduce stress & regain focus Functional breath work is research based & used by top athletes. Ignore old myths about breathing being just spiritual Episode highlights 0:00 Introduction 01:09 Why 5.5 breathing matters 03:10 How to measure breath & nervous system health 13:53 How breath work boosts recovery & performance 17:42 Practical tools for safer, smarter breathing 47:11 Common breathing myths & mistakes 56:13 The FivePointFive platform & future of breath work Links Watch it on YouTube: https://youtu.be/8UwPvUohZec Full episode show notes: outliyr.com/229 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick
“I can never get a good workout in… I don't have the time.” I hear it all the time, especially from busy women. But get ready to learn the best way NEVER to say that statement again! In this episode, I sit down with Ulrich Dempfle, the CEO of CAROL, to talk about why carving out even a few minutes for exercise in midlife can be a total game-changer. Ulrich explains that the right movement is one of the most powerful things you can do to boost health span, energy, and quality sleep. So we dive into the science of VO₂ max and mitochondrial function (which start to decline in our 30s), and how efficient workouts can slow that process dramatically. For busy women in midlife, heart health and metabolic health are front and center, and CAROL's unique approach makes it possible to train smarter, not longer, for ultimate health. Tune in here to learn all about CAROL, and discover how quick, intentional exercise can fit seamlessly into your hectic life WITHOUT sacrificing results! Ulrich Dempfle Ulrich Dempfle is the CEO and co-founder of CAROL Bike. He began his career as a mechanical engineer in Germany's automotive industry, but later became a healthcare system consultant and is now a fitness tech pioneer. Ulrich's personal fitness transformation is proof of CAROL's power. He stresses the importance of not only improving fitness but also delaying the aging process. By significantly improving his own VO2max, CAROL Bike has helped him turn back the clock on aging and keep it there. IN THIS EPISODE Positive and healthy alternatives to long cardio exercises Comparing the benefits of different training methods All about CAROL, and how it can help you get your energy back How 5 minutes on the CAROL bike can be transformative for you Physical, mental, and cognitive benefits of the CAROL bike The science behind short, effective, rehit workouts How CAROL is ideal for supporting women's unique hormonal shifts in perimenopause and menopause Use the code MARIZA to claim $100 OFF your CAROL bike! QUOTES “Unfortunately, with aging, we all lose about 10% of our VO2 max per decade. So it's a progressive thing. It starts from around 30, and if you don't do something about it, you will lose fitness progressively throughout your life.” “Based on the feedback we're receiving, [we] make it as simple as possible and take as many barriers away to actually stick to a workout and reap the benefits that are available from this ultra short, super efficient workout.” RESOURCES MENTIONED Preorder the Perimenopause Revolution and get your VIP ticket to the Perimenopause Solution event http://hayh.site/pr_bl_ap-snyder_a_opt Get $100 off your CAROL bike HERE with code: MARIZA https://carolbike.pxf.io/GK3LaE CAROL YouTube CAROL Instagram CAROL Facebook RELATED EPISODES #546: How to Stay Lean, Energized and Strong By Working With Your Physiology, Not Against It with Dr. Stacy Sims #646: The Number One Exercise Hack I'm Doing Daily In Peri To Burn Fat, Build Lean Muscle and Boost Energy & Mental Clarity #552: The Midlife Muscle Crisis: Why Maintaining Muscle Is Necessary For Fat Loss, Strength and Longevity with Dr. Gabrielle Lyon 672: Unbreakable: How to Build a Body And Life That Defies the Rules of Aging with Dr. Vonda Wright
Gravel Union Talks is a podcast series full of inspiring stories, news and events from the world of gravel biking. Each month hosts Carlo and Olly will be chatting with guests who are passionate about riding off the beaten track… adventure riding, bike packing and gravel racing. In this episode:Matt Hart from TorqGravel Union Talks podcast with hosts Carlo van Nistelrooy and Olly Townsend.GU's editor-in-chief Olly on last month's most popular articles on the Gravel Union platform.Want to bring in ideas for topics or guests? Mail Olly at info@gravelunion.cc Check out our platform and socials : www.gravelunion.ccInsta: @gravel_union / Facebook: https://www.facebook.com/GravelUnion/Komoot: https://www.komoot.nl/user/1080024447202JOIN US NOW FOR FREE on www.gravelunion.ccShownotes:Matt Hart: Torq websitehttps://www.torqfitness.co.ukThe Gear – Wahoo Trackr heart rate monitorIf your typical gravel ride prioritises views over VO2 max, friends over FTP and having-a-good-time over heart rate zones, then Wahoo's Trackr heart rate monitor probably isn't for you. But, on the other hand if you'd like to try and enhance your fitness levels, efficiently burn off a few more calories or even sign up for a gravel race, then read on, as this gadget could be just what you need.The Gear – Hydration VestsIf you're heading out for a quick ride then it's easy enough to grab a wattle bottle, fill it with the beverage of your choice and head out the door. But what if you're going to be out all day, or for multiple days, or you want to carry more things than you can cram in your jersey pocket? A hydration vest might be the answer, so we've put together an overview of three of the best. The Gear - Torq Explore Supercharged Adventure FoodTorq might be better known to some of you as purveyors of nutrition products for use during rides – energy drinks/gels/bars/jellies etc but did they also know that they make a range of “adventure foods” too? At first glance these might look like they're primarily aimed at bikepackers and ultradistance riders (which they are), but Olly has found another perfectly good use for them during shorter duration gravel rides too.
Send us a textIn this podcast episode, I am once again chatting with one of my old mates Aaron Deere about the science of longevity. In particular in this episode we focus on how fitness, strength training, and cardiovascular health are critical to aging well. I always enjoy bringing Aaron on to the podcast and this conversation is certainly right up my street.In this episode we talk about evidence-based strategies for maintaining health span, including VO2 max testing to bone density, muscle mass preservation, and practical exercise prescriptions. Our conversation challenges the notion of quick-fix supplements for longevity, emphasising instead the importance of consistent, personalised physical activity across every life stage. Listen in to discover actionable insights into how you can optimise your fitness and potentially extend your lifespan and improve your overall quality of life.Links mentioned in this episode:The LiftMor Trial Thanks for listening to our podcast and please feel free to get in touch: Tweet us at @fmedassociates Follow us on Instagram or Facebook @petewilliams_fma Email us on info@fm.associates For more information about our services please visit our website www.functional-medicine.associates We would love to hear from you!
You ask, I answer! This month the Qs are a little nutrition heavy, but we are also covering beer miles, medal displays, VO2 max, and a whole lot more! See the full list of Qs and the meme/GIF As at http://DizRuns.com/1314. Love the show? Check out the support page for ways you can help keep the Diz Runs Radio going strong! http://dizruns.com/support Become a Patron of the Show! Visit http://Patreon.com/DizRuns to find out how. Get Your Diz Runs Radio Swag! http://dizruns.com/magnet Subscribe to the Diz Runs Radio Find Me on an Apple Device http://dizruns.com/itunes Find Me on an Android http://dizruns.com/stitcher Find Me on SoundCloud http://dizruns.com/soundcloud Please Take the Diz Runs Radio Listener Survey http://dizruns.com/survey Win a Free 16-Week Training Plan Enter at http://dizruns.com/giveaway Join The Tribe If you'd like to stay up to date with everything going on in the Diz Runs world, become a member of the tribe! The tribe gets a weekly email where I share running tips and stories about running and/or things going on in my life. To get the emails, just sign up at http://dizruns.com/join-the-tribe The tribe also has an open group on Facebook, where tribe members can join each other to talk about running, life, and anything in between. Check out the group and join the tribe at https://www.facebook.com/groups/thedizrunstribe/
Following on from her breast cancer diagnosis in 2021, TV presenter Julia Bradbury joins Liz to reveal how we can be healthier and fitter than ever before after recovery.Julia shares how her cancer diagnosis changed her attitude to her health and the valuable insights she has since gained from genetic testing.Liz and Julia also dig deep into VO2, grip strength and balance as markers of longevity, chat through their lifestyle strategies to prioritise brain health. They also bond over their shared love of the outdoors for better health. Links mentioned in the episode:Hack Yourself Healthy by Julia BradburyFollow Julia Bradbury on InstagramITV Julia Bradbury Breast Cancer and Me Lifecode GX genetic testingEat to beat disease in midlife - with Aaron DeereHooke ClinicWhat to eat to beat disease - with Dr William LiFollow Dr Nasha Winters on InstagramAvoid osteoporosis, frailty and immobility - with Dr Vonda WrightNutrigenomics for wellbeing - with Emma BeswickA Better Second Half by Liz EarleHave a question for Liz? Send a WhatsApp message or voicenote to 07518 471846, or email us at podcast@lizearlewellbeing.com for the chance to be featured on the showPlease note, on some occasions, we earn revenue if you click the links and buy the products, but we never allow this to bias our coverage and always honestly review. For more information please read our Affiliate Policy. Hosted on Acast. See acast.com/privacy for more information.
Luke Way, founder of Isocapnic Technologies, reveals how respiratory limitations affect athletic performance and how proper breathing training can unlock significant performance gains.• Approximately 70% of athletes are functionally limited by their respiratory systems, meaning they physically cannot breathe enough air to perform at their true potential• VO2 max testing provides valuable insights beyond just a number, showing how different body systems contribute to or limit performance• Many athletes compensate with rapid, shallow breathing (up to 70 breaths per minute) instead of utilizing their full lung capacity• Breathing deeper rather than faster is more efficient as each breath contains "dead space" air that doesn't participate in gas exchange• The Isocapnic device allows athletes to train respiratory muscles without hyperventilation, conditioning them for sustained deep breathing• Nasal breathing is beneficial for low-intensity activities but physically cannot meet ventilation demands during high-intensity exercise• Proper respiratory training can reduce the energy cost of breathing from 18% to 8% of total energy expenditure during endurance activities• Blood work several times per year helps athletes monitor important markers like ferritin levels to optimize training and recovery• Consistency in training, recovery, and injury management is the ultimate differentiator for athletic successFor more information about respiratory training and to connect with Luke Way, visit Isocapnic Technologies online or reach out at Kelowna Hockey Fest.Support the show Check out our Website | Twitter | LinkedIn | Instagram | Tiktok | Spotify | Apple | Google | Youtube l Save 20% on Perfect Sports Supplements
In this episode of the Optimal Aging Podcast, Jay Croft speaks with Dr. Jonathan Graff-Radford, a Mayo Clinic neurologist and co-author of the new edition of the Mayo Clinic Guide to Alzheimer's and Other Dementias. They discuss how Alzheimer's disease begins 20 years before symptoms appear, what can be done to prevent or delay it, and what health and fitness professionals working with people over 50 need to know now.Dr. Radford shares powerful new insights on early detection tools, lifestyle factors like exercise and hearing loss, and how fitness protocols can support cognitive health. You'll also hear how dual-tasking workouts, VO2 max, and neuroplasticity play a role in long-term brain health.If you serve older adults in health, fitness, or wellness, this is a must-listen.
Hello everyone. Welcome to the latest episode of The Matchbox Podcast powered by Ignition Coach Co. I'm your host, Adam Saban, and on this week's episode we're talking about how to execute workouts targeting maximum aerobic power, ways to periodize your training for general fitness, and then we share ideas for how to maintain (or even improve) fitness while going through a season of decreased training time. As always, if you like what you hear make sure to share this with your friends and leave us a five star review and if you have any questions for the show drop us an email at matchboxpod@gmail.com with the topic of discussion in the email title or head over to ignitioncoachco.com and fill out The Matchbox Podcast listener question form. You can also sign up for the Matchbox Patreon and get priority placement for your submitted questions. Alight let's get into it! For more social media content, follow along @ignitioncoachco @adamsaban6 @dizzle_dillman @dylanjawnson @kait.maddox https://patreon.com/MatchboxPodcast?utm_medium=unknown&utm_source=join_link&utm_campaign=creatorshare_creator&utm_content=copyLink https://www.youtube.com/c/DylanJohnsonCycling https://www.ignitioncoachco.com https://www.youtube.com/@DrewDillmanChannel Intro/ Outro music by AlexGrohl - song "King Around Here" - https://pixabay.com/music/id-15045/ The following was generated using Riverside.fm AI technologies Summary This conversation delves into the intricacies of VO2 max workouts, the importance of maximizing aerobic power, and strategies for building consistent fitness. The hosts discuss how to approach off-season training, emphasizing the need for intentionality in workouts and the balance between intensity and volume. They also explore the significance of maintaining fitness while reducing training hours, particularly through cross-training and strategic planning. Chapters 00:00 Understanding VO2 Max Workouts 11:50 Maximizing Aerobic Power Training 15:13 Building Consistent Fitness 23:00 Off-Season Training Strategies
Today we dive into your awesome questions with what might be one of our longest podcasts to date. We tackle back pain and bad bike position. We get into the best lifting exercises for performance. We look at the power behind tackling non-traditional triathlons and other events. We look at how to be faster and stronger as you age. Vo2 max as seniors. How do you know when you need a break. Capitalizing on race fitness or flirting with burnout? And We put the spotlight on ourselves to find out what we preach but don't always follow. Topics: Back pain Bad bike position When to get new shoes for cycling and running Complex lifting for strength and speed Do the best triathletes lift heavy?? What advice to we give out but not always follow? Do we look at workouts we give and think, "man, I'm glad I'm not doing that." Non traditional triathlons Being a well rounded athlete Keep triathlon as your base focus but branch out Capitalizing on fitness gained from a race or flirting with burnout? 60+ athletes and speed, strength, and injury prevention How to tell when it's time to take a break from swim, or bike, or run What do you want to be doing in 10 years? When do I go from a online training plan to a coach? What coaches are good for Mike Tarrolly - mike@c26triathlon.com Robbie Bruce - robbie@c26triathlon.com
Vi svarer på lytterspørsmål: hvorfor mindre volum og høyere innsats ofte gir bedre resultater, hvordan du kan teste VO2‑max (4x4/Cooper), hvorfor sykling sjelden gir samme puls som løping, og hvorfor grundig oppvarming (20+ min) reduserer skader. Praktiske råd for å trene hardere — men smartere. .
We kick this one off AMA-style and with a tasty update: Buttered Maple Bacon Keto Brick is back as a seasonal drop this Sunday, the 14th, at noon Central. We talk fall vibes, pecan butter and chunks, and why the cacao-butter version hits just right. We also run through how we're leveling up the Natural State Savages show: bigger medals and trophies (plus a fun surprise), premium venue with dedicated dressing rooms and a backstage livestream, on-site shirt printing, top-tier vendors and a DEXA Fit tie-in, a smoother running order, and even family-friendly touches like getting the kids involved. My dad's smoking barbecue butts all night and Stan's grilling chicken, and judges' feedback will happen upstairs in a single session. Competitor registration closes Sunday the 21st so we can finalize bios and peak-week logistics; spectator tickets are on the same site.In the AMA, we cover a lot: sucralose isn't doomsday but we still lean to stevia/monk fruit; you don't need carbs to run if you're deeply fat-adapted (we reference our VO2 testing and staying mostly in Zone 3). For building, accept a reasonable body-fat window—about 12–15 percent for most guys—while pushing progressive overload. We reframe “cheat days” into on-plan free meals during non-prep phases. On a budget? Eggs, ground beef, and buying from local farmers still win, and bricks are cost-effective per calorie. Protein shakes are overrated versus real food, especially when isolates crank up GI issues. We close with a reverse-diet playbook (bump protein first, then fats, progress weekly, phase out refeeds as daily intake rises) and advice for perimenopause/menopause: eat enough, lift with intent, and prioritize muscle and bone.If this one sparks more questions, send them our way for the next AMA.Greg Mahler is also a lifetime natural bodybuilder, and can be followed on Instagramhttps://www.instagram.com/ketogreg80/Register For My FREE Masterclass: https://www.ketobodybuilding.com/registration-2Get Keto Brick: https://www.ketobrick.com/Subscribe to the podcast: https://open.spotify.com/show/42cjJssghqD01bdWBxRYEg?si=1XYKmPXmR4eKw2O9gGCEuQ
Discover the truth about your body fat percentage and why your bathroom scale is lying to you. In episode 813 of the Savage Perspective Podcast, host Robert Sikes sits down with Dexafit's Jerry Bylers to reveal what a DEXA scan truly says about your body composition, visceral fat, and bone density. They analyze Robert's personal results from years of a ketogenic diet, exploring his resting metabolic rate, VO2 max, and how his body has become incredibly efficient at burning fat for fuel, offering a deep dive into understanding the data that drives real progress.Ready to transform your own body composition? Join Robert's FREE Bodybuilding Masterclass to learn the proven strategies to build muscle and burn fat effectively. Sign up here: https://www.ketobodybuilding.com/registration-2Get Keto Brick: https://www.ketobrick.com/Subscribe to the podcast: https://open.spotify.com/show/42cjJssghqD01bdWBxRYEg?si=1XYKmPXmR4eKw2O9gGCEuQChapters:0:00 - What is a DEXA Scan? 0:35 - Navy Vet's New Mission in Arkansas 1:48 - From Navy Retirement to Fitness Expert 2:54 - How a Simple Chat Started a Business 4:15 - No More 3-Hour Drives For This Test 5:24 - Hospital-Grade Tech For Everyday People 8:28 - See Your Body Data on a Big Screen TV 10:53 - Stop Guessing, Start Knowing Your Body 12:15 - My Exact Body Fat Percentage Revealed 14:20 - How Much "Bad" Fat Am I Storing? 15:59 - The Muscle Index That Predicts Longevity 19:45 - Are You "Big Boned?" The Truth 22:47 - Your Skeleton Weighs HOW MUCH?! 24:51 - How Often Should You Get a DEXA Scan? 27:32 - Find Out Your TRUE Calorie Burn (RMR) 31:43 - My Shocking Cardio Fitness Score 34:12 - The Ultimate Fitness Marker Explained (VO2 Max) 39:17 - Sugar-Burner vs. Fat-Burner: What Fuel Do You Use? 43:30 - 10+ Years on a Ketogenic Diet Did THIS to My Metabolism 46:32 - The Keto Advantage: A "Nearly Unlimited" Fuel Source 50:12 - Why All Lifters Need Good Cardio 52:25 - Finding Out My "Biological Age" 55:32 - Special Offer: FREE 3D Body Scan 58:39 - The Winning Combo for Bodybuilders 1:01:40 - Why Every Athlete Needs This Data 1:02:45 - How To Book Your Own DEXA Scan
In this episode of the Movement Logic Podcast, Dr. Sarah Court and Laurel Beversdorf critically evaluate the claims made by YogaU Online about the connections between breathing practices and bone health during a recent promotional webinar for a new workshop called “Breath As Medicine: Yogic Breathing for Vital Aging.” They meticulously analyze research studies cited by YogaU, debunking pseudoscientific assertions about nitric oxide production, VO2 max, and the impact of breathing on bone density. The hosts highlight the ethical implications of such misleading information and emphasize the importance of evidence-based practices in the fitness and yoga communities. The discussion also touches on marketing tactics that prey on the fears of older women, underscoring the need for transparency and integrity in health advice.Sign up for the Bone Density Course Interest List here!Movement Logic on Instagram03:48 Calling Out Pseudoscience05:19 Yoga U's Dubious Claims17:47 The Breath as Medicine Workshop18:39 Debunking the Claims32:57 Understanding Breathing Pathologies01:01:56 Lung Function and Bone Mineral Density: A Study Review01:03:57 Debunking Misleading Claims in Yoga Marketing01:09:38 Sleep Apnea Studies and Their Misuse01:17:57 Hypoxia and Bone Health: Misinterpretations01:23:23 Nitric Oxide and Aging: Separating Fact from Fiction01:41:02 Cardiovascular Fitness: Misconceptions and Realities01:50:47 Yoga U's Ethical Dilemma and Call for Accountability01:59:38 Conclusion and Call to ActionReferences:Episode 5 Does Yoga Asana Build Bone Density?Episode 38 Got Bones? Yoga Asana Isn't EnoughEpisode 79 Make YogaU Make SenseEpisode 92 Make Dr. Loren Fishman Make SenseTwelve-Minute Daily Yoga Regimen Reverses Osteoporotic Bone LossRecognizing and Treating Breathing Disorders: A Multidisciplinary Approach by Leon ChaitowBreath: The New Science of a Lost Art by James NestorAssociation between lung function and bone mineral density in children and adolescentsAssessment of Bone Mineral Density and Bone Metabolism in Young Men with Obstructive Sleep ApneaBone Mineral Density and Changes in Bone Metabolism in Patients with Obstructive Sleep Apnea SyndromeHypoxia is a Major Stimulator of Osteoclast Formation and Bone ResorptionMolecular Mechanisms Involved in Hypoxia-Induced Alterations in Bone RemodelingFront Page Fitness podcastYoga Meets Movement Science podcast
In this episode, Dr. Matt Kaeberlein sits down with Joel Jamieson to explore the science of heart rate variability and how it connects to longevity, recovery, and performance. Joel shares his journey from training elite fighters to becoming a global authority on HRV training, emphasizing that healthspan is built on consistency, balance, and resilience rather than endless high-intensity workouts. The discussion dives into why VO2 max is one of the strongest predictors of longevity, how the parasympathetic nervous system and vagus nerve health regulate stress and recovery, and why zone 2 cardio, metabolic flexibility, and steady improvements in cardiovascular health matter more than chasing short-term results. This conversation reframes strength vs endurance, highlights key anti-aging biomarkers, and shows how recovery science can transform both athletes and everyday people seeking lasting health.
Lauren Rosenberg, a highly experienced Physician Associate, has dedicated nearly two decades to Internal Medicine and Health Optimization. Driven by a passion for preventative care, Lauren founded Vent Health to shift the focus from disease treatment to prevention. She specializes in a personalized approach that blends genetics, epigenetics, biomarkers, and lifestyle factors to tailor health interventions that extend and optimize each patient's healthspan. Lauren's practice includes prescribing peptides (GLP, CLP/GIP) for weight loss, insulin resistance, pre-diabetes, etc. This episode concentrates on MENOPAUSE. Lauren and Heather discuss what symptoms could be related to Menopause. Lauren will speak about hot flashes, heart palpitations, frozen shoulder, brain fog, lack of libido, itchy ears, anxiety, trouble sleeping, hair changes, urinary tract infections. They will discuss what can you do at home and what treatments can be beneficial from professionals, such as GLP 1's for weight gain and hormone replacement options. Lauren is a frequent speaker at the Age Management Medicine Group (AMMG) and the American Academy of Anti-Aging Medicine (A4M) conferences. Lauren's practice includes Cardiology prevention: Diagnostics and AI analysis to detect dangerous plaque and calcium; advanced lipid testing and cardiovascular genetics Longevity biomarkers: DNA methylation for biological age, VO2 max testing, Telomere health; Therapeutic plasma exchange Cancer prevention: methylated DNA screens, preventative MRIs, tumor marker testing. Lauren's Website: https://myventhealth.com/about/ Heather's Website: www.heatherthomson.com Social Media: IG: https://www.instagram.com/iamheathert/ You Tube: https://youtube.com/@iamheathert?si=ZvI9l0bhLfTR-qdo SPONSORS: BLISSY: Blissy is offering 60-nights risk-free PLUS an additional 30% off when you shop at www.Blissy.com/HEATHERPOD and use code HEATHERPOD. Your hair and skin will thank you! AIRDOCTOR: Go to AirDoctorPro.com and use promo code HEATHER to get UP TO $300 off today! AirDoctor comes with a 30-day money back guarantee, plus a 3-year warranty—an $84 value, free! Get this exclusive, podcast-only offer now at www.AirDoctorPro.com using promo code HEATHER. Learn more about your ad choices. Visit megaphone.fm/adchoices
Andy, Rick, and Sarah host this week's episode at Garmin's HQ in Southampton, UK, in front of a live audience as they dive into exactly what you can expect at your autumn marathon training. From training tips to race day tricks, we've got you covered!Rick learns what VO2 max is as he tests out the brand new Garmin Fenix 8 Pro, Sarah recaps an epic week at UTMB, and Andy shares his nerves and excitement ahead of starting his marathon training block for Valencia!Check out the new Garmin Fenix 8 Pro here!The Running Channel Podcast tackles one big topic each episode, amongst helpful tips and light-hearted chat on the latest news in the running world. Hosted by Sarah Hartley (amateur runner) and Andy Baddeley (former pro runner) alongside Rick Kelsey (recovering runner), the TRC Podcast is friendly, jargon-free, and the perfect accompaniment to your runs. Join The Running Channel Club for exclusive additional podcast episodes, bite-sized courses, live Q&As and so much more! Head to club.therunningchannel.comFor all enquiries contact podcast@therunningchannel.com .If you liked this, please subscribe wherever you get your podcasts. And leave us a 5* review and rating, it really helps us get discovered.We're on YouTube too, so check us out there: www.youtube.com/runningchannel .Mentioned in this episode:Use code THERUNNINGCHANNEL to get 15% off for the next two weeksUse code THERUNNINGCHANNEL to get 15% off for the next two weeks
If you're interested in boosting your cardiovascular fitness, I've got three steps for you to do. Your cardiovascular fitness - VO2 max - is the most powerful predictor of longevity. Together with your lower body strength, they will tell the story of your future. What is VO2 max? Oxygen consumed in milliliters per kilogram per minute. Strongest predictor of longevity, alongside lower body strength. VO2 Max and muscle mass peaks typically at age 25, with studies suggesting an average annual reduction of about 1% after. Increasing your VO2 max can significantly increase your longevity. It can reduce all-cause mortality by 10-25%. Just going from low to above-average fitness levels can reduce mortality risk by 60-70% over a decade. The 3 Steps to Improve Cardio Fitness 1. Long slow aerobic exercise Walking, hiking, biking, swimming. Work just below threshold (can talk, slightly breathy). 80% of the time will be spent here. 20% should be spent doing HIIT or strength training. 2. High-Intensity Interval Training (HIIT) 10-15% improvement in 5-10 weeks 15–30 seconds of breathless effort (sprinting effect). Breathless in 30 seconds or less. 3. Strength training Improves muscle, may enhance your body composition or weight Improving both your fitness (oxygen delivery and use) and reducing weight means your ml/kg/min will go up as you consume more oxygen with less body weight .. and even if you don't lose weight your muscle is metabolically active and consumes oxygen while fat doesn't. So let's come back to the value of VO2 for reducing all cause mortality. A modest increase of 3.5 ml/kg/min (1 MET) is all it takes to reduce all-cause mortality by up to 25%. How do you know your Cardio Fitness is improving? Short of getting a VO2 max test, you can measure in other ways: Resting heart rate – first thing in morning Recovery heart rate at end of interval and one minute later One-mile walk test Why Muscle Still Matters? More muscle = higher oxygen demand → better VO2 Max. Fat mass doesn't contribute to oxygen use. Muscle quality declines with age → requires smarter training, especially during menopause. Watch this episode on Flipping50TV YouTube. References: Journal of American College of Cardiology. 2018, PMID: 30384883. Circulation. 2007, PMID: 17548726. Other Episodes You Might Like: Previous Episode - 80 Lb Perimenopausal Weight Loss After Corporate Burnout Next Episode - From Your Mouth to Your Gut: Hearing Health Whisper More Like This - Extended Cardio and Low Protein Equal Short Term Weight Loss Resources: Join the Hot, Not Bothered! Challenge to learn why timing matters and why what works for others is not working for you. Use Flipping 50 Scorecard & Guide to measure what matters with easy at-home self-assessment test you can do in minutes. Are you burning belly fat or burning out? Get the Menopause Fitness Guide to High-Intensity Interval Training to help you lose more fat and stay on track!
Proactive Health, Optimized Longevity The healthcare system is built around reaction—but what if we flipped the script? Join biochemist Phil George and Jason from Healthspan Longevity for a groundbreaking conversation about proactive health strategies that redefine aging and wellness. *Why Healthspan Matters More Than Lifespan—Because living long isn't the same as living well. Learn how to maximize your quality of life through longevity science. *The Power of Proactive Testing*—Advanced diagnostics like DEXA scans, VO2 max tests, cognitive assessments, and metabolic rate analysis detect health risks _before_ symptoms appear. *Key Pillars of Longevity*—Discover how sleep, nutrition, exercise, social engagement, and emotional well-being work together to create a thriving, resilient body and mind. *Beyond “Normal” Health Markers—Why standard lab results aren't enough and how aiming for optimal ranges unlocks better long-term outcomes. *Cognitive and Olfactory Testing—Surprising insights into how early changes in smell and memory can signal brain health shifts—and what you can do about it. *The Truth About Nutrition & Supplements—When dietary patterns matter more than pills, and why a _food-first approach_ is key to sustainable health. *Personalized, Data-Driven Strategies—Because longevity isn't one-size-fits-all. Learn how individual health trends shape better, tailored recommendations. If you're ready to move from reactive to proactive, this episode is packed with the science and strategies to help you live better, longer. Tune in to revolutionize your approach to health and longevity! Available now on all podcast platforms. Please feel free to email Phil at philgeorge@charter.net with any health/nutrition/exercise questions. https://www.wellnesswave.net/
Време е за още един вълнуващ епизод от #realitycheck сериите ни. В него тестваме нашите VO2 max и други важни телесни показатели, които ще Ви покажат още информация, ако искате и Вие да разберете повече за спсобностите на Вашето тяло и за това как се справяте в спортния си път. Благодарим за съдействието на DexaFit София, които любезно направиха нашите тестове и откликнаха да ги анализираме заедно чрез техния управляващ директор Денис Колев, който и довежда световната компания у нас. Тестовете, които направихме бяха за VO2 max, което е показател за аеробната издръжливост и кардиореспираторната форма, който представлява максималното количество кислород, което тялото може да използва по време на интензивна физическа активност. По-високата стойност на VO2 max означава, че тялото по-ефективно използва кислорода за производство на енергия, което води до по-добра издръжливост, по-малко умора и по-добро цялостно здраве. VO2 max. е показател за атлетичната производителност и трябва да се увеличава, когато нивото на физическата Ви подготовка се подобрява. Водещият световен експерт по дълголетие Питър Атия вярва, че VO2 max може да се счита за показател на продължителността на живота. Познавайки Вашият VO2 max можете да таргетирате Вашите тренировки спрямо целите, които имате, а именно да възстановявате, горите мазнини или тренирате сърцето и аеробната си издръжливост по-добре. Сканирахме и телата си с DexaFit скенер, който дава информация за телесния състав, разпределението на подкожните мазнини и нивата на висцералните мазнини. Здравето на опорно-двигателния апарат, оценка на състоянието на мускулите, симетрията, силата на скелета и потенциалните рискове, свързани със саркопения и остеопороза. Оценка на рисковете за здравето, биологичната възраст и потенциалните рискове за заболявания като сърдечни болести и диабет. Направихме си и Resting Metabolic Rate (RMR) тест, който показва скоростта на метаболизма ни в покой - броят на калориите, които тялото изгаря без да правим нищо. От изследването става ясен и коефициента на дихателна обмяна (RER), който разкрива предпочитаните от тялото Ви източници на гориво. В теста ще разберете и сърдечния си ритъм в покой, което предоставят ценна информация за риска от заболявания, които ще попречат на Вашето дълголетие. С данните от изследването може да подобрите диетата си за оптимална енергийна ефективност и избягване на преяждане или недояждане, след като вече знаете точните си калорийни нужди и предпочитано гориво. DexaFit София: https://www.sofia.dexafit.com/bg ул. „Атанас Дуков“ 32 088 358 1717 Приятно гледане и слушане! Последвай ни и в: Facebook: https://bit.ly/2FJlMHl https://www.youtube.com/@LegendiBG Instagram: https://www.instagram.com/legends__podcast/ Twitter: https://twitter.com/LegendiLegends Spotify: https://open.spotify.com/show/4hTic33jhXgBh31GM6AEYL Apple Podcasts: https://podcasts.apple.com/bg/podcast/legendi-legends/id1538275381 SoundCloud: https://soundcloud.com/cfcjgwgp3shy Deezer: https://www.deezer.com/us/show/2067872?deferredFl=1 - Георги Харизанов Веселин Вълчев Легенди / Legends Българският подкаст
What if you could get twice the health and brain benefits of traditional cardio in just five minutes?I know, it sounds impossible. Most people think they need to spend 45 minutes on a treadmill to see real results, but the science shows otherwise.In today's episode, I'm diving into one of the smartest, most time-efficient workouts I've ever come across. It's called REHIT and studies show it can improve your VO2 max, boost your mood, supercharge learning and even cut your risk of metabolic disease by over 60%.I'll share how this simple shift in training can literally rewire your brain for focus, memory, and performance, while giving you back hours of your life each week.Joining me is Ulrich Dempfle, CEO and Co-Founder of Carol Bike, who helped take this groundbreaking science out of the lab and into a form anyone can use at home.If you've ever said, “I don't have time to exercise,” this conversation is going to change the way you think about fitness, brain health, and what's possible in just two 20-second sprints./ / / Are you ready to take the next step on your brain optimization journey? / / /Choose your own adventure. Below are the best places to start:>>> CAROL Bike>>> Kwik Mind Supplement>>> Join Limitless Live 2025 in San Diego 8-10 December>>> Discover Your Unique KWIK BRAIN C.O.D.E To Activate Your GeniusTake your first step by choosing one of the options above, and you will find everything you need to ignite your brilliant brain and unlock your exceptional life, allowing you to achieve and surpass all of your personal and professional goals.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this solo episode, Dr. Stephanie explores the benefits of high-intensity interval training (HIIT) for women in perimenopause and menopause. Inspired by an Instagram poll, she highlights how sprinting and HIIT improve longevity, cardiovascular health, and muscle maintenance. Dr. Stephanie discusses VO2 max, the importance of fast-twitch muscle fibres, and the hormonal effects of aging. She prescribes low-impact HIIT options like cycling and elliptical, with an eye on the AI-driven CAROL bike for efficiency.Save $100 with code BETTER at https://carolbike.com As the doctor says, 'Today is the oldest you've ever been and the youngest you'll ever be, so why not start now?'Episode Overview (timestamps are approximate):(0:00) Intro/Teaser(3:00) Benefits of High Intensity Interval Training(8:00) Improving Bone Density and VO₂ Max(16:00) Sprint Training for Muscle Fibre Health(27:00) Impact of Menopause on Exercise(42:00) Efficient, Personalized Workouts With CarolResources mentioned in the episode can be found at: https://drstephanieestima.com/podcasts/ep432/We couldn't do it without our sponsors:LIFT - If you want muscle for longevity, clarity, and confidence—come LIFT with me. Head over to https://drstpehanieestima.com/lift and join today.PURALITY HEALTH - Zinc is my go‑to for immune resilience, skin integrity, and day‑to‑day vitality. Go to https://puralityhealth.com/better and use code BETTER for 10% off your first purchaseAPOLLO - The Apollo wearable supports energy, focus, relaxation, and sleep by syncing with your rhythms. Go to https://apolloneuro.com/better to check it out and use code BETTER to receive $60 off your purchase.BIOPTIMIZERS-MAGNESIUM - Magnesium Breakthrough contains multiple types of magnesium plus cofactors like B6 to enhance absorption. Visit https://bioptimizers.com/better and use code BETTER to save 15%.EIGHT SLEEP - If you're going through menopause or just struggling with night sweats, you have to try this. Head over to https://eightsleep.com/drstephanie and use the code DRSTEPHANIE to get $350 off your Pod 5 Ultra.
Phil Batterson is a competitive runner, former running coach, and the founder of Critical Oxygen. Phil has a PhD in human bioenergetics and a love for all sorts of endurance sports, from rowing to track and field and ultras. His goal with Critical Oxygen is to teach athletes and coaches how to optimize their physiology to maximize endurance performance. This episode is important and is a repost of episode 330 from 2023. Phil breaks down some of the complex physiology behind the three different thresholds to make it more accessible, as well as providing practical ways to apply it in training. Some of our discussion includes: Phil's journey into endurance training and exercise science What physiology defines each of the three thresholds How runners can determine their own thresholds The importance of lactate threshold work for race preparation Common mistakes when using training zones How to integrate VO2 max work with cross training Whether you like to geek out on physiology or just want to race faster, you'll learn a lot from my conversation with Phil! Links & Resources from the Show: Follow Phil on Instagram Check out the Critical Oxygen podcast and blog Let me help you get the most out of your training Thank you to 2Before! We are supported by 2Before, a powerful sports supplement made from New Zealand Blackcurrants designed to increase endurance, manage inflammation, support immunity, and promote adaptation. 2Before helps to boost performance by increasing blood flow, making it more efficient for the body to pump oxygenated nutrient-rich blood into the muscles. Just like beetroot but more effective, blackcurrant berries are vasodilators, helping you get more blood flow to where it's needed. Boost your performance and immune system with 2before: use code JASON for 30% off 20 packs and multi-serve packs at 2Before.com. Thank you to 2Before for supporting Strength Running! Thank you LMNT! A big thanks to LMNT for their support of this episode! They make electrolyte drinks for athletes and low-carb folks with no sugar, artificial ingredients, or colors. They are offering a free gift with your purchase at LMNT. And this does NOT have to be your first purchase. You'll get a sample pack with every flavor so you can try them all before deciding what you like best. LMNT's products have some of the highest sodium concentrations that you can find. Anybody who runs a lot knows that sodium, as well as other electrolytes like magnesium and potassium, are essential to our performance and how we feel throughout the day. If you're not familiar, LMNT is my favorite way to hydrate. They make electrolytes for athletes and low-carb folks with no Sugar, artificial ingredients, or colors. I'm now in the habit of giving away boxes of LMNT at group runs around Denver and Boulder and everyone loves this stuff. Boost your performance and your recovery with LMNT. They're the exclusive hydration partner to Team USA Weightlifting and quite a few professional baseball, hockey, and basketball teams are on regular subscriptions. So check out LMNT to get a free sampler pack and get your hydration optimized for the upcoming season. Thank you Gut & Green! Previnex's new Gut & Green Superfoods powder is my new go-to. It has organic barley and oat grass, alfalfa, spirulina, chlorella, kale and broccoli… and that's it. Their ingredients are backed by clinical data and contain three specific gut fibers that help promote GI health, digestion, reduced inflammation, and a better microbiome. With twice of the fiber of my last greens mix and a better flavor, it's a no brainer for me. Try it for yourself here at previnex.com and be sure to use code “JASONGREENS” to save 15% off your first order. Don't tell anyone, but if you put Gut & Green Superfoods powder in your cart, then the 15% off discount will work for anything else you add into your cart as well. Thanks Gut & Green!
Support your health journey with our private practice! Explore comprehensive lab testing, functional assessments, and expert guidance for your wellness journey. Find exclusive offers for podcast listeners at nutritionwithjudy.com/podcast. _____What if the sugar diet isn't working because of sugar, but because of protein restriction?FGF-21 is similar to a metabolic reset switch, powerful when used occasionally, but risky if left on all the time. Chronic activation often comes with trade-offs such as muscle loss, hormonal changes, and nutrient deficiencies. Robert Sikes and I talk about how the Sugar Diet may leverage FGF-21 but that there are ways to leverage FGF-21 without using sugar. Robert Sikes is the founder of Keto Brick. He has been following a ketogenic lifestyle for over a decade and turned professional in bodybuilding in 2023. Through his work, Robert coaches athletes and everyday people to optimize performance, build muscle, and achieve sustainable health without extreme dieting or performance-enhancing drugs.In this episode, I sit down with Robert Sikes (aka Keto Savage) to unpack his latest self-experiment: eating 4,000 calories per day with 400g of fat and minimal protein, and doubling his testosterone in just 2 weeks.We discuss the following: Why the sugar diet became popularRobert's diet experimentAre some not built for low carb?Recommended protein macrosWhat is VO2 max testingHow long to get fat adaptedRobert's keto bodybuilding programOptimal testosterone rangeLessons from 11 years of ketoRobert's cacao sourcing journeyWhere to find Robert SikesJudy's pull-up journey (bonus)_____EPISODE RESOURCESInstagramKeto BrickKeto SavageKeto BodybuildingNatural States SavagesSavage Perspective PodcastNwJ Interview with Robert Sikes Part 1NwJ Interview with Robert Sikes Part 2NwJ Interview with Robert Sikes Part 3NwJ Interview with Robert Sikes Part 4EFH Personalized Health Plan_____WEEKLY NEWSLETTER
Your fancy smartwatch is lying to you about your VO2 max, and chasing that number is sabotaging your race timesMost runners obsess over VO₂ max, but few really understand what it means or how to use it. In this episode, I break down the truth about what VO₂ max actually measures, why your watch might be misleading you, and how to train in a way that builds lasting fitness. If you've ever wondered why your numbers don't match how strong you feel, or how to make sense of VO₂ workouts without burning out, this conversation will give you the clarity and tools to get there.Key TakeawaysVO2 max shows your genetic potential for using oxygen, but having a high number doesn't guarantee fast race times.Smartwatches often give inaccurate VO₂ max numbers because they can't measure things like sleep, recovery, or stress.The right workouts and patience can help you train smarter, improve steadily, and unlock real race-day performance.Timestamps[00:15] What You'll Learn[00:49] Vo2 Max Defined[03:29] How To Improve Your Vo2 Max[07:24] Use This To Improve Your Vo2 Max Now[08:03] Run Science Nerd Break - Vo2 Max Tops Out[09:03] Why Smart Watches Get It All Wrong[09:51] Why You Need Patience To Improve Your Vo2 Max[11:01] Use This To Get a Higher Vo2 Max and Race FasterLinks & Learnings
“ Don't waste your time and money on things that are perishable. Invest in yourself,” explains Vonda Wright, M.D. Vonda Wright, M.D., double board-certified orthopedic surgeon, internationally recognized sports medicine expert, and member of mindbodygreen's board of scientific advisors, shares a powerful new lens on longevity—one that's rooted in science, shaped by mindset, and powered by muscle. Here are the key points: - Aging is a superpower (~3:28) - The six time bombs of aging (~7:25) - Building mental resilience (~9:35) - Muscle, brain, bone (14:00) - The frailty line & VO2 max (~15:00) - Creatine dosage (~18:10) - Metabolism & muscle (~21:15) - What's overrated vs. underrated (~23:50) - Blood work & menopause (~31:55) - Wright's personal practices to decrease inflammation (~33:40) - Type 2 muscle fibers (~36:50) - Advice to her younger self (~41:00) - Closing thoughts (~44:40) Referenced in the episode: - Follow Wright on Instagram (@drvondawright) - Pick up her book, Unbreakable: A Woman's Guide to Aging with Power - Check out her website (https://www.drvondawright.com/) - Listen to her previous episode (Why women should lift heavier & eat more) We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices
Walking speed predicts your risk of death better than cholesterol—and this episode reveals why. You'll learn how to test your biological age at home in just 10 seconds, and how to use that information to upgrade your human performance, extend your longevity, and tailor your biohacking strategy for maximum results. Discover the overlooked role of pelvic floor strength, glute activation, and neuromuscular training in brain optimization, metabolism, and injury prevention. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey speaks with Dr. Vonda Wright, a double board-certified orthopedic surgeon, hormone optimization expert, and elite sports medicine pioneer who's worked with Olympic athletes, military special forces, and high-performing women through every phase of life. With decades of experience in functional medicine, movement science, and hormone therapy, Dr. Wright shares the essential strategies to prevent frailty, rebuild strength, and thrive through perimenopause and beyond. You'll learn: • How walking speed reveals aging and longevity better than traditional blood tests • The biomechanics behind muscle “shutdown” and how to turn muscles back on • The truth about C-sections, pelvic floor rehab, and functional motion assessments • Which supplements, nootropics, and hormone therapies restore metabolism and vitality • Why perimenopause is a turning point for brain, bone, and cardiovascular health • Testing tools and training methods to upgrade strength, prevent falls, and age powerfully Whether you want to feel stronger, think sharper, or stay youthful into your 90s, this is your roadmap for smarter not harder biohacking with real-world impact. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: 10-second walk test longevity, pelvic floor dysfunction and aging, glute activation for brain health, perimenopause hormone replacement therapy, VO2 max biohacking, estrogen for bone density, neuromuscular reactivation exercises, functional movement assessment AI, post-C-section core recovery, velocity training for longevity, strength vs muscle mass aging, menopause testosterone therapy, mitochondrial health for women, sleep optimization progesterone, cold therapy for muscle recovery, fascia training for anti-aging, diastasis recti long-term effects, smart exercise hacks for aging, hormone optimization for libido and brain, smarter not harder fitness protocols Thank you to our sponsors! Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino. Resources: • Vonda's Website: https://www.drvondawright.com/ • Vonda's Instagram: https://www.instagram.com/drvondawright/?hl=en • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer1:23 — Intro2:55 — Muscle Atrophy and Reactivation6:10 — Pelvic Floor Health and Rehab8:47 — Joint Mobility and Movement10:02 — Science of Muscle Function18:23 — Perimenopause and Menolescence27:58 — Four Essential Female Hormones42:50 — VO2 Max and Longevity49:24 — Velocity Training and Bone Health62:30 — Turning Menopause into Power65:58 — Closing Thoughts and Book Rec See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
¿Dónde está el verdadero límite del cuerpo humano?
By age 50, you've already lost half of your NAD levels—and without it, your energy, mind, and health decline faster. In this powerful episode, Dr. Kerry Gelb continues his conversation with Harvard-trained physician, NAD expert and CMO in Wonderfeel Youngr™ NMN Dr. Andrew Salzman to explore how NAD impacts blood pressure, muscle growth, VO2 max, sleep quality, heart health, and even eye diseases like glaucoma and macular degeneration. Discover how lifestyle factors like poor sleep, stress, refined carbs, and sedentary habits deplete NAD—and how exercise, diet, and smart supplementation (NMN, NR, resveratrol, hydroxytyrosol, ergothioneine) can restore it.
How to be a strong runner even as you ageWe all know the saying, "Age is just a number," but when it comes to running, that number can sometimes feel like a roadblock. However, I'm here to tell you that with the right approach, you can absolutely continue to improve your speed and perform at your best, no matter your age. So, let's explore how to stay fast as the years go by!Let's dive in! First off, it's important to understand what changes as we age. Muscle mass starts to decline after age 30, which affects our strength and speed. Also, aerobic capacity (the ability of your heart and lungs to provide oxygen to your muscles) tends to decrease with age. This makes it harder to sustain faster paces.But here's the good news: these age-related changes aren't permanent. By being proactive in our training, we can maintain and even enhance our running performance over time.Don't compare yourself to pro or olympic athletes. You aren't a pro.
Just finished your race season? Don't jump straight into base training! September-October is actually PRIME TIME for targeting your biggest limiters and making breakthrough improvements. With your peak fitness still in the bank from racing, this crucial 8-week window lets you focus on quality sessions without race stress - whether that's getting explosive with anaerobic power, experimenting with new threshold intervals like over-unders, or trying constant power VO2 max work instead of your usual 30/30s. It's the perfect time to experiment with volume, cadence, equipment changes, and push your limits when you have the mental bandwidth to truly focus. Remember: base training needs 3-4 focused months, not endless zone 2, so use this time to squeeze that extra 1% out of your season! Check out our coaching services and training plans if you need help structuring this focused approach. Chapters:00:00 - Introduction & Common Questions02:15 - Who This Strategy Is For04:30 - Why Train Limiters Instead of Taking a Break07:45 - Using Your In-Season Fitness Bank10:20 - Experimentation Without Race Pressure13:00 - Anaerobic Power Training Focus17:30 - Threshold & VO2 Max Training22:45 - Mixing Quality Sessions with Fun Rides25:10 - Timeline Adjustments for Different Climates27:30 - Why Not to Jump Straight to Base Training29:00 - Final Thoughts & ResourcesJoin this channel to get access to videos a month early! And it directly supports the channel so we can bring you more content!https://www.youtube.com/channel/UCS9FDuHl_qp8ajqQuWwNtew/join
Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3079: Eric Leija breaks down the pros and cons of LISS and HIIT, revealing that while HIIT offers faster fat loss and aerobic gains in less time, LISS may be more sustainable and supportive of muscle preservation. The takeaway: the most effective cardio is the one you'll actually stick with, consistency beats intensity if enjoyment is missing. Read along with the original article(s) here: https://www.ericleija.com/liss-vs-hiit-which-approach-is-better-for-fat-loss/ Quotes to ponder: "While HIIT may be more effective for fat loss, it's not a good long-term strategy if you dread the activity so much you avoid it." "One study found that it took around 6-8 weeks of LISS to achieve the same amount of aerobic endurance (VO2 max) improvement seen in just 2 weeks of consistent HIIT." "While a 20 minute HIIT workout can burn as many calories as a 40-60 minute LISS workout, the HIIT exercise also boosts your metabolism for up to 24 hours afterward." Learn more about your ad choices. Visit megaphone.fm/adchoices
Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3079: Eric Leija breaks down the pros and cons of LISS and HIIT, revealing that while HIIT offers faster fat loss and aerobic gains in less time, LISS may be more sustainable and supportive of muscle preservation. The takeaway: the most effective cardio is the one you'll actually stick with, consistency beats intensity if enjoyment is missing. Read along with the original article(s) here: https://www.ericleija.com/liss-vs-hiit-which-approach-is-better-for-fat-loss/ Quotes to ponder: "While HIIT may be more effective for fat loss, it's not a good long-term strategy if you dread the activity so much you avoid it." "One study found that it took around 6-8 weeks of LISS to achieve the same amount of aerobic endurance (VO2 max) improvement seen in just 2 weeks of consistent HIIT." "While a 20 minute HIIT workout can burn as many calories as a 40-60 minute LISS workout, the HIIT exercise also boosts your metabolism for up to 24 hours afterward." Learn more about your ad choices. Visit megaphone.fm/adchoices
Hello everyone. Welcome to the latest episode of The Matchbox Podcast powered by Ignition Coach Co. I'm your host, Adam Saban, and on this week's episode we're talking about how to incorporate mountain bike skills into your training program, whether or not heat training is beneficial for athletes who don't compete in the heat, and how to interpret data from VO2max and Lactate testing. As always, if you like what you hear make sure to share this with your friends and leave us a five star review and if you have any questions for the show drop us an email at matchboxpod@gmail.com with the topic of discussion in the email title or head over to ignitioncoachco.com and fill out The Matchbox Podcast listener question form. You can also sign up for the Matchbox Patreon and get priority placement for your submitted questions. Alight let's get into it! For more social media content, follow along @ignitioncoachco @adamsaban6 @dizzle_dillman @dylanjawnson @kait.maddox https://patreon.com/MatchboxPodcast?utm_medium=unknown&utm_source=join_link&utm_campaign=creatorshare_creator&utm_content=copyLink https://www.youtube.com/c/DylanJohnsonCycling https://www.ignitioncoachco.com https://www.youtube.com/@DrewDillmanChannel Intro/ Outro music by AlexGrohl - song "King Around Here" - https://pixabay.com/music/id-15045/ The following was generated using Riverside.fm AI technologies Summary In this conversation, the hosts discuss various aspects of mountain biking, including skill improvement, training strategies, and the importance of heat training. They emphasize the necessity of spending time on trails to enhance biking skills and the benefits of private lessons for personalized feedback. The discussion also covers the significance of heat training for overall performance, even in cooler conditions, and the value of understanding VO2 max and lactate thresholds for effective training. Regular testing is highlighted as a means to track progress and make informed adjustments to training plans. Chapters 00:00 Improving Mountain Biking Skills 11:30 The Benefits of Heat Training 18:37 Understanding VO2 Max and Lactate Thresholds
Send us a textEpisode OverviewIn this solo episode of The Own It Show, Justin Roethlingshoefer continues his 4-part series on cellular restoration—this week focusing on the critical role of oxygen in healing, performance, and longevity. Justin breaks down why oxygen isn't just about breathing—it's the fuel of life at the cellular level. From VO2 max to nasal breathing, he explains how to reclaim your energy, sharpen your mind, and add years to your healthspan by training smarter, not just harder.If you've ever felt chronically tired, foggy, or like your workouts just aren't working anymore, this episode will help you connect the dots—and take action.Key Timestamps00:00 Introduction: The Importance of Oxygen00:16 Welcome to the On It Show01:45 Understanding Cellular Health04:00 The Role of Oxygen in Cellular Function08:30 Measuring Oxygen Efficiency: VO2 Max18:46 Practical Tips for Improving Oxygen Efficiency27:12 Conclusion and Next StepsEpisode Highlights● Oxygen = Energy: Learn why oxygen is the most overlooked yet essential factor in healing and energy production. ● The Power of VO2 Max: Discover how this single metric outperforms smoking and cholesterol as a predictor of longevity. ● You're Not Just Tired—You're Under-Oxygenated: Brain fog, poor sleep, and slow recovery might not be age or stress—it might be oxygen inefficiency. ● Train the System, Not Just the Muscles: Why many fit people still burn out—and how to change that by improving oxygen delivery. ● Practical Protocols: Justin shares a clear, actionable framework to improve VO2 max through breath work, zone 2 cardio, high-intensity intervals, and key nutrients.Action Steps● Test your VO2 max: Use the 12-minute run method to estimate your baseline. ● Start breath training: Practice nasal breathing and breath holds to improve CO2 tolerance. ● Train in Zone 2: Get 180 minutes/week of steady-state cardio at 60–70% of your max heart rate. ● Add VO2 Max Intervals: 30 minutes/week of short bursts at 90–100% of your max heart rate. ● Eat for Oxygen: Boost nitric oxide with beets, pomegranates, cordyceps, citrulline, and optimize iron + B vitamins for red blood cell health. ● Track HRV: Use Oura, WHOOP, or another device to monitor adaptation and cellular readiness.“Are you just breathing, or are your cells fully alive?” Let this question guide your n=========================== Subscribe and Listen to the Own It Show HERE: ➡︎ YouTube:https://www.youtube.com/@justinroethlingshoefer➡︎ Apple Podcasts:https://apple.co/3KCyN3j➡︎ Spotify: https://open.spotify.com/show/3F58Ez4lbIKQ6kMu2pfpIG =========================== Resources: ⚡️CHECK OUR PROGRAMS: https://ownitcoaching.com/programs/⚡️BOOK: https://thepowerofownershipbook.com/ =========================== Connect with Justin Roethlingshoefer on Social Media: ➡︎ linkedin.com/in/justin-roethlingshoefer➡︎https://www.instagram.com/justinroeth/?hl=en Own It Success is different so own your different!
Think more data means better health? Dr. Zain Hakeem challenges the obsession with endless biomarkers & breaks longevity down to its core drivers. You'll see how effect size, simplicity, consistency, beat the latest trends & how to bioharmonize your lifestyle around what truly works. Meet our guest Dr. Hakeem is a dual board-certified physician in Internal Medicine & Pediatrics, with a background in philosophy from LSU & a medical degree from Texas College of Osteopathy. He practices both primary & hospital medicine, blending acute care insight with preventative strategies. He's the creator of the Rx-Bayes app, which helps doctors interpret diagnostic accuracy through a statistical lens. On his YouTube channel, he breaks down health misinformation, explores true longevity optimization, & discusses why meaning is essential to living well. Thank you to our partners Outliyr Biohacker's Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Focus on five key drivers like VO2 max, strength, social connections, not smoking & blood pressure instead of chasing 100+ biomarkers Prioritize interventions with the biggest impact on lifespan rather than spending energy on minor or unproven strategies Avoid mistaking correlation for causation by digging deeper into the real reasons behind trends Recognize that the number of social interactions directly influences mortality risk & shouldn't be overlooked Improve VO2 max & strength through exercise to dramatically cut mortality risk even with simple changes Avoid Goodhart's Law by targeting true overall strength instead of isolated metrics like grip strength Choose practices with real effects backed by evidence rather than wasting time chasing small wins Optimize both quantity & quality of life by aiming to enjoy more years not just add them Understand that both too much & too little sleep carry risks while exercise may be more influential than sleep alone Rely on interventions supported by strong human evidence like clinical trials & Bradford Hill criteria Episode Highlights 3:36 5 Longevity Drivers That Matter Most 10:07 What the Research Gets Wrong 25:19 VO2 Max, Strength & Social Health Deep Dive 40:02 Exercise, Adaptation & Anti-Fragility 47:18 The Limits of Stacking & Testing 1:08:21 Redefining Longevity, Sleep & What Really Matters Links Watch it on YouTube: https://youtu.be/YhcdonAJm8M Full episode show notes: outliyr.com/220 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick
In today's episode, I'm joined by Adam Kadela, co-founder of DexaFit and DexaFit Dx. A former athlete and trader turned health tech entrepreneur, Adam set out to make advanced diagnostic testing, like DEXA scans and VO2 max, accessible outside of elite labs and into everyday wellness routines.We talk about the evolution of DexaFit from local clinics to a global platform trusted by athletes and doctors. He explains why tracking the right metrics matters, how often to test, the truth about body recomposition, the best ways to lower visceral fat, and what most people get wrong about wearables and weight loss.Leave Us A Voice Message! | https://telbee.io/channel/4_b9zzx58wdkuwirqkcxwa/Topics Discussed: → What does a DEXA scan reveal about your health?→ How often should you get a body composition test?→ Why is visceral fat more dangerous than body fat?→ Can blue light exposure affect weight gain?→ How does VO2 max relate to longevity?Sponsored By: → AG1 | Get a FREE 1-year supply of Vitamin D3+K2 AND 5 free AG1 Travel Packs with your first subscription at drinkAG1.com/bewell→ Be Well By Kelly Protein Powder & Essentials | Get $10 off your order with PODCAST10 at bewellbykelly.com→ Hiya Health | Get 50% off your first order at HiyaHealth.com/Kelly and give your kids the full-body nourishment they need to grow into healthy, happy adults.→ WeNatal | You can use my link, wenatal.com/kelly, with any subscription order, to get a free one month supply of WeNatal's Omega DHA+ Fish Oil valued at 35 dollars.→ Vuori | Get 20% off your first order of Vuori AND free shipping on orders over $75 at vuori.com/kellyTimestamps: → 00:00:00 - Introduction → 00:03:01 - Adam's background → 00:07:09 - DEXA & D1 athletes → 00:11:53 - Breaking down a DEXA scan→ 00:15:12 - Women's bone health → 00:22:41 - DEXA's data & frequency → 00:26:31 - Body recomp tips → 00:32:07 - Body fat & body composition → 00:35:43 - Aging & muscle loss → 00:37:45 - Understanding DEXA scan results → 00:42:14 - Lowering visceral fat → 00:48:27 - Blue light, weight gain, & intermittent fasting → 00:52:13 - VO2 max & resting metabolic rate → 00:56:47 - Gym testing (IN BODY)→ 00:59:26 - Lean mass & watching the scale → 01:05:11 - Wearable recommendations Check Out DexaFit:→ Get 25% off with code BEWELL25 at https://www.dexafit.com/redeem-code→ InstagramCheck Out Kelly:→ Instagram→ Youtube→ Facebook
Is Zone 2 cardio really the key to longevity and fat loss—or have we been misled? In this solo episode, Louisa challenges the fitness status quo and reveals why low-intensity steady-state cardio might be wasting your time—especially if you're a woman. Drawing on new 2025 research and her deep background in exercise physiology, Louisa explains how men and women respond differently to training, and why higher-intensity workouts may be far more effective for improving mitochondrial health, brain aging, VO2 max, and metabolic flexibility. If you're a woman in your 30s, 40s, 50s, or 60s trying to optimize your longevity, brain function, and body composition—this is a must-listen. True optimization and longevity never come from comfort alone. You'll learn: Why Zone 2 may not improve mitochondrial health like you think The real training zones that boost VO2 max, fat oxidation & brain function How perimenopausal and menopausal women must train differently The exact weekly routine to optimize longevity, body comp & cognition *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Troscriptions: Head to www.troscription.com/neuro | Code: NEURO for 10% your first order Boncharge: Head to www.boncharge.com | Code: NEURO15 for 15% off Ketone IQ: Head to www.ketone.com/NEURO for 30% OFF your subscription order + receive a free gift with your second shipment. Manukora: Head to www.manukora.com/neuro to save up to 31% plus $25 worth of free gifts with the Starter Kit. *** I'm Louisa Nicola — clinical neuroscientist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ *** Topics discussed: 00:00:00: Exercising in zone 2 is a waste of time 00:00:43: Research that shifted her views, especially for women 00:01:41: What Is Zone 2? – Definition and physiology explained 00:02:17: Zone 2 in Practice – How it's measured in real-world settings 00:03:23: Comfort Zone Training – Why Zone 2 is easy but not effective 00:04:16: Elite Athletes vs. The Rest of Us 00:05:10: Why intensity matters more 00:08:11: Time efficiency and real-life experience 00:09:23: Brain Health & Mitochondria – Higher intensity for cognition 00:10:15: Why Zone 2 doesn't have special signaling power 00:12:25: Why higher zones burn fat better 00:13:35: Zones 1 through 5 explained 00:14:00: Zone 5: The Death Zone 00:15:18: Menopause & Muscle Fibers 00:16:55: Lactate Fuels the Brain 00:18:11: How to Train for Longevity – Resistance, intensity, and logic 00:23:59: VO2 Max 00:26:40: Norwegian 4x4 and weekly training strategy 00:30:00: Resistance Training 101 – 5x5 sets, compound lifts, and strength focus 00:31:38: Zone 2 as Recovery – When and how to actually use it 00:33:07: Final Takeaway – Zone 2 isn't bad, but it shouldn't be your priority
In recent years “Zone 2 training” has gained immense popularity in fitness and health circles, often being proclaimed the “best” cardiovascular training for metabolic health. Zone 2 training is sustained, low-intensity exercise below the lactate threshold that is commonly employed by many elite level endurance athletes, with a variety of proposed performance benefits. This led to interest from health-conscious folks about its ability to improve markers like VO2 max and mitochondrial function, which are associated with better health outcomes and longevity. Prof. Brendon Gurd, an exercise physiologist at Queen's University, is the co-author of a recent review published in Sports Medicine that examined some of the claims made around zone 2 training and health in the general population. This episode looks at whether the evidence truly supports Zone 2 as a uniquely effective training zone or if this hype has outpaced the research. These insights help professionals and individuals make evidence-based recommendations and avoid unintended negative consequences of following certain ideas. About The Guest Dr. Brendon Gurd is a Professor in the School of Kinesiology and Health Studies at Queen's University, where his research focuses on exercise physiology and skeletal muscle adaptation. His work explores how different intensities and types of exercise influence mitochondrial content and function in muscle tissue, with the goal of understanding how to optimize health and performance through training. Timestamps [03:23] Discussion with Professor Brendan Gurd [05:56] Zone two training: Mechanisms and misconceptions [10:56] Practical applications and recommendations [22:16] Research gaps and future directions [35:47] Key ideas segment (Sigma Nutrition Premium) Links to Resources Subscribe to Sigma Nutrition Premium Join the Sigma email newsletter for free Enroll in the next cohort of our Applied Nutrition Literacy course List of Sigma's Recommended Resources Review paper: Storoschuk et al., 2025 – Much Ado About Zone 2: A Narrative Review Assessing the Efficacy of Zone 2 Training for Improving Mitochondrial Capacity and Cardiorespiratory Fitness in the General Population Lecture Slides: Prof. Brendon Gurd – Is Zone 2 the optimal intensity for inducing mitochondrial adaptation?
Rhonda Patrick, Ph.D. (@foundmyfitness) is a biomedical scientist and the founder of FoundMyFitness, a platform dedicated to delivering rigorous, evidence-based insights on improving healthspan and mitigating age-related diseases.Sponsors:Helix Sleep premium mattresses: https://HelixSleep.com/Tim (27% off all mattress orders)Momentous high-quality creatine and other supplements: https://livemomentous.com/tim (code TIM for up to 35% off)David Protein Bars 28g of protein, 150 calories, and 0g of sugar: https://davidprotein.com/tim (Buy 4 cartons, get the 5th free.)Monarch Money track, budget, plan, and do more with your money: MonarchMoney.com/Tim (50% off your first year at monarchmoney.com with code TIM)Timestamps:[00:00:00] Start.[00:04:54] Dealing with aging parents and other topics on the table.[00:10:43] How a common multivitamin helps reverse cognitive and memory aging.[00:12:04] The importance of supplementation — especially as we age.[00:13:10] Effectively supplementing with omega-3 fish oil to counter APOE4 and Alzheimer's risks.[00:16:50] The CoQ10 and omega-3 protocol that has helped Rhonda's father manage Parkinson's symptoms for nearly a decade.[00:19:28] Sulforaphane: a potent NRF2 activator with an unexpected benefit for Rhonda's mother's tremors.[00:25:34] How Rhonda convinced her mom to start CrossFit and the power of community-based, senior-focused fitness.[00:26:52] The earlier the intervention, the better the outcomes.[00:32:25] Intermittent fasting vs. extended fasting and my own results.[00:44:31] Does fasting destroy muscle mass? Debunking the catabolism fear and understanding the crucial role of the re-feeding phase.[00:57:24] "Dirty" fasting: what really happens to autophagy and metabolic benefits when you add a splash of cream or MCT oil to your coffee?[01:00:44] VO2 max: the one metric that may predict lifespan more accurately than anything else, and how we work to improve it.[01:12:07] How a two-year exercise program reversed heart aging by 20 years in previously sedentary, middle-aged adults.[01:16:18] Lactate isn't the enemy: how vigorous exercise creates a superfuel that protects and grows the brain.[01:20:30] The optimal sauna protocol (temperature and frequency) for slashing dementia risk by 66%.[01:29:17] If you're human, you'll find a use for curcumin.[01:30:43] Creatine for cognition: moving beyond the gym with a powerful, science-backed tool for focus and combating sleep deprivation.[01:42:41] Still vitamin D deficient despite taking supplements? Here's the critical cofactor you're probably missing.[01:53:52] Shocking sources of microplastics in our daily lives, including chewing gum and teabags.[02:04:10] The uncomfortable truth about "moderate" alcohol consumption, cancer risk, and why the "sick quitter" hypothesis makes most older studies unreliable.[02:17:03] The ups and downs of ketamine and psilocybin on cognition and longevity.[02:24:19] Parting thoughts and where to find more from Rhonda.*Show notes for this episode: https://tim.blog/2025/07/24/dr-rhonda-patrick/For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Brian Kennedy is a renowned biologist, leader in aging research, and director of the Center for Healthy Longevity at the National University of Singapore. In this episode, Brian shares insights from ongoing human aging studies, including clinical trials of rapamycin and how dosing strategies, timing, and exercise may influence outcomes. He presents two key models of aging—one as a linear accumulation of biological decline and the other as an exponential rise in mortality risk—and explains why traditional models of aging fall short. He also explains why most current aging biomarkers lack clinical utility and describes how his team is working to develop a more actionable biological clock. Additional topics include the potential of compounds like alpha-ketoglutarate, urolithin A, and NAD boosters, along with how lifestyle interventions—such as VO2 max training, strength building, and the use of GLP-1 and SGLT2 drugs—may contribute to longer, healthier lives. We discuss: Brian's journey from the Buck Institute to Singapore, and the global evolution of aging research [2:45]; Rethinking the biology of aging: why models like the hallmarks of aging fall short [9:45]; How inflammation and mTOR signaling may play a central, causal role in aging [14:15]; The biological role of mTOR in aging, and the potential of rapamycin to slow aging and enhance immune resilience [17:30]; Aging as a linear decline in resilience overlaid with non-linear health fluctuations [22:30]; Speculating on the future of longevity: slowing biological aging through noise reduction and reprogramming [33:30]; Evaluating the role of the epigenome in aging, and the limits of methylation clocks [39:00]; Balancing the quest for immortality with the urgent need to improve late-life healthspan [43:00]; Comparing the big 4 chronic diseases: which are the most inevitable and modifiable? [47:15]; Exploring potential benefits of rapamycin: how Brian is testing this and other interventions in humans [51:45]; Testing alpha-ketoglutarate (AKG) for healthspan benefits in aging [1:01:45]; Exploring urolithin A's potential to enhance mitochondrial health, reduce frailty, and slow aging [1:05:30]; The potential of sublingual NAD for longevity, and the combination of NAD and AKG for metabolic and exercise enhancement [1:09:00]; Other interventions that may promote longevity: spermidine, 17
VO2 max intervals are flashy, hard, and wildly misunderstood. In this solo episode, I break down how to actually use VO2 max work to boost your HYROX performance without burning yourself into the ground.You'll learn:What VO2 max training actually is (and what it's not)Why your heart rate data might be lying to youHow to structure intervals that build speed, power, and toleranceWhen VO2 work makes you stronger… and when it's just junk volumeAnd how to use it wisely inside group fitness or CrossFit-style programmingRMR Training APP Podcasthttps://www.rmr.training/rmr-app-podRMR Training App- Communityhttps://www.rmr.training/rmr-training-app-2Off- Seasonhttps://www.rmr.training/base-builder-podcast
You've got an hour or less to train, what do you do? Spencer Martin of the Beyond the Peloton newsletter & podcast + WEDU's Outcomes / The Move takes a break from the Tour de France to join Choose the Hard Way creator Andrew Vontz to talk about what they do when life and work are at max stress and you have little time to workout. Is Zone 2 really the right move if you have a few hours a week to train and you're a cyclist, runner or triathlete with a long training history and navigating highly stressful moments in work, family and life? Should you follow a rigid training program or freestyle? Vo2 max intervals every time the road goes uphill, Zwift racing, Zwift pace partners, bodyweight workouts, push-ups & pull-ups before the kids wake up at 5 a.m. are some of the methods Andrew and Spencer use to get fit when they can in the time they have. As we age, family, parenting, work, health, wellness and just staying alive start to become higher priorities. But we all still want to go fast when it's time to run, ride or get out there and tackle that gravel monument. Andrew Huberman and Peter Attia have many great ideas about how to make that happen, this conversation focuses more on the practical versus the perfect. What gets done is what works, and many people struggle to fit it all into the day. Whether you're racing Unbound, BWR, Mid South, Overland, Gravel Worlds or just a busy parent who enjoys running, riding, lifting, hybrid training, Hyrox or being able to get up off the floor after a Netflix binge without injuring yourself, your fascia and breathwork will thank you for listening to this stunning episode. Leave a comment or DM @hardwaypod and let us know what you think of this new experimental episode format. The number one way to support Choose the Hard Way is to become a paid subscriber to https://alwaysthehardway.substack.com/. That's where I share my reflections on these interviews and write about engaged mindfulness, bikes and life. At https://www.onerealvoice.com/, Andrew Vontz coaches leaders 1:1 to help them thrive as storytellers and stand out in the long-form podcast conversations where real influence is built. If you have a podcast or are starting one, I also provide strategic guidance to set yourself up to win from the beginning and keep on winning with every episode. When you're ready to be great, DM me @hardwaypod or send an email to hello@onerealvoice.com Wherever you're listening to this podcast, please subscribe and do humanity a favor when you hit 5 stars. Crypto curious? With over $1 trillion in transactions to date, https://www.blockchain.com/ is your trusted partner on your crypto journey. Create your free wallet and get up to 10% in annual rewards by putting your crypto to work. Go to Blockchain.com to get started today, no experience required. Choose the Hard Way Newsletter: https://alwaysthehardway.substack.com/ One Real Voice podcast coaching & strategy: https://www.onerealvoice.com/ Beyond the Peloton Newsletter: https://beyondthepeloton.substack.com/