POPULARITY
Categories
Análise pós-jogo da partida entre CRB x Fortaleza, válida pela 14ª rodada da Série B do Campeonato Brasileiro. Vem com a turma! CRB é superior no primeiro tempo, abre o placar com golaço de Mikael e só não amplia o placar graças a João Ricardo, que salva o Fortaleza e mantém o tricolor vivo na […]
Nick Hodge, Co-Owner of Digest Publishing and editor of Foundational Profits and Underground Alpha, joins us for our monthly longer-format discussion on different macroeconomic factors and market reactions to the war in the Middle East, his key takeaways from 2 different site visits to South Dakota and Wisconsin, and investing strategies in select copper, gold, and critical minerals stocks. We start off reviewing the mix of macroeconomic movers and knock-on effects from geopolitics as it relates to the closure of Strait of Hormuz, the US/China meetings last week, projections around central bank monetary policy options, rising bond yields and interest rates, a strengthening US dollar, GDP growth, rising inflation, sovereign debt loads, and AI datacenter buildouts. The US stock markets have shrugged off most of these economic datapoints and geopolitical news, continuing to blast up to new all-time highs over the last week. He points out that the CRB commodities index has also been strong lately, lead by base metals, soft commodities, and the energy space. When reviewing the commodities, it has been hard to ignore the strength in the copper pricing, which has been up at all-time highs over the last few weeks of May, and Nick shares his approach is to investing in the copper equities. For exposure to the base metals producers he has been positioned in the iShares MSCI Global Metals and Mining Producers ETF (PICK), which has performed quite well over the last year and especially in 2026. Nick reiterated points from our prior conversation about 2 of the copper developers with good investor engagement, solid pounds in the ground resources, and good fundamental catalysts being: Gunnison Copper Corp. (TSX: GCU) (OTCQB: GCUMF) and Aldebaran Resources Inc. (TSX-V: ALDE) (OTCQX: ADBRF). Nick highlighted the recent acquisition of Arizona Sonoran Copper Company Inc. (TSX:ASCU | OTCQX:ASCUF) by Hudbay Minerals Inc (TSX, NYSE: HBM) and how that may be used as a good case study and lens for consideration of other advanced copper development assets and what kind of projects and jurisdictions may interest the senior producers. Gladiator Metals Corp. (TSXV: GLAD) (OTCQB: GDTRF) is a copper and gold exploration story in Nick's portfolio that just released some high-grade intercepts in the Yukon, and still has a lot of drilling on tap for this season as a catalyst. When reviewing why he prefers safer jurisdictions in the Americas for copper investing, he did point out a company like Ivanhoe Mines (TSX: IVN) (OTCQX: IVPAF) is an exception, due to the quality of the management team to navigate the risks when operating in Africa. Next we got a boots-on-the-ground recap of Nick's 2 recent company site visits: Lion Rock Resources Inc. (TSXV: ROAR) (FSE: KGB) (OTCQB: LRRIF) – The company recently announced Phase One drill results at their Volney Project in South Dakota. The system features high-grade lithium, tin and tantalum hosted within spodumene-bearing LCT (Lithium-Cesium-Tantalum) pegmatites. GreenLight Metals Inc. (TSXV: GRL) (OTCQB: GRLMF)- GreenLight is a Wisconsin-focused exploration company advancing copper-gold and gold projects across the Penokean Volcanic Belt-one of North America's most prospective VMS districts. GreenLight's Wisconsin portfolio includes the Bend copper-gold deposit, the Reef high-grade gold project, and the Lobo and Lobo East massive sulfide targets. We wrapped up getting the near-term technical price support levels that Nick is watching for in gold. For now he is not concerned about gold falling into a true bear market, and he is treating the pullback we've seen in the precious metals a buying opportunity. Any short-term consolidation in pricing should be juxtaposed against the fundamental structural drivers for the longer-term precious metals bull market that are all still solidly in place. He's been using periods of sector weakness in the PMs to add to positions in both GDXJ and Royal Gold, Inc. (NASDAQ: RGLD), along with some other junior precious metals stocks. Click here to follow Nick's analysis and publications over at Digest Publishing For more market commentary & interview summaries, subscribe to our Substacks: The KE Report: https://kereport.substack.com/ Shad's resource market commentary: https://excelsiorprosperity.substack.com/ Investment disclaimer: This content is for informational and educational purposes only and does not constitute investment advice, an offer, or a solicitation to buy or sell any security. Investing in equities and commodities involves risk, including the possible loss of principal. Do your own research and consult a licensed financial advisor before making any investment decisions. Guests and hosts may own shares in companies mentioned.
Análise pós-jogo da partida entre CRB x Fortaleza, válida pelo jogo de volta da 5ª fase da Copa do Brasil 2026. Vem com a turma! Mais um objetivo alcançado! Parece que esse é o lema da Era Carpini no Fortaleza. Campeão estadual, semifinal da Copa do Nordeste, briga na parte de cima da Série B […]
On the latest episode of Minor Issues, Mark Thornton opens with a detailed analysis of the gold correction. Is the three-month decline a sign that inflation is over, or a temporary reallocation driven by war? The answer is in the data: the CRB commodity index continues to climb, the money supply is at an all-time high, and there is no evidence of deflation anywhere in the price structure. The inflation regime remains firmly in place, and the gold correction is a normal feature of bull markets whose real-world zigzags get smoothed away on long-term charts.The second half features a panel interview from VRC Media with Rick Rule, hosted by Darrell Thomas. Rule lays out the case for a decade-long commodity super cycle driven by 30 years of underinvestment in productive capacity. He delivers a sobering calculation: $39 trillion in on-balance-sheet federal debt plus $120 trillion in off-balance-sheet unfunded entitlement promises (a combined $160 trillion against $170 trillion in total private American net worth). The only realistic resolution, Rule argues, is a "dishonest default," inflating away the purchasing power of the dollar, just as happened in the 1970s when the dollar lost 75% of its value. Mark concurs, noting that the money supply is growing at record pace even as Washington insists it's being "restrictive."Mark's "Gold vs CRB Index" graph is available here: https://mises.org/MI175_GraphThe original VRIC interview is online here: https://www.youtube.com/watch?v=3kMiiC08TNo20% off listener offer on the new insulated Minor Issues tumbler and three of Mark's books, signed if ordered by the end of April: https://mises.org/MinorIssuesTumbler. Use coupon code Thornton.Be sure to follow Minor Issues at https://Mises.org/MinorIssues
Análise pós-jogo da partidade entre Fortaleza x CRB, válida pelo jogo de ida da fase 16 avos de final da Copa do Brasil 2026. Vem com a turma! Fortaleza tem segundo tempo melhor, e com um gol de Miritello, consegue buscar a virada pra cima do CRB. Vantagem de apenas um gol para a volta […]
Former Hawaiʻi Governor George Ariyoshi passes away at 100; HPR reports on the current status of CRB on Molokaʻi.
Notre Dame's Tocqueville professor of political science, Vincent Phillip Munoz (Phil to his freinds and colleagues), joins this special episode which finds all three of your regular bartenders in the same room for once while on the road in Austin, Texas. Phil is one of the leading scholars of religious liberty in the U.S., and after a progress report on the Iran War (we're still winning), and a prolonged look at the Supreme Court oral arguments in Trump v. Barbara, the birthright citizenship case heard this week, we pick Phil's brain about the status of school prayer, and whether a restoration of organized prayer in public schools has a prayer of happening, taking as our cue Gerry Bradley's recent and provocative First Things article, "How To Bring Back School Prayer."From there we briefly (but alas because we were out of sufficient time) but inadequately treat Phil's terrifically concise CRB essay "Ancient and Modern: How Straussians Interpret the Founding," mostly to annoy John Yoo—and we succeeded!
O Vitória bateu o CRB e se recuperou na Copa do Nordeste após estreia com derrota para o Botafogo-PB, em jogo que usou um time alternativo. Podcast debate planejamento e primeiros atos no regional, que tem a equipe como grande favorita. Edição também faz um balanço da atuação do clube na janela de contratações do primeiro semestre.
Estamos #NOAR! Em partida elétrica e de muitos gols, Vitória vence o CRB fora de casa pelo Nordestão. Vem acompanhar!
Claremont Review of Books published an issue in Spring 2025 called "Let's Not Do That Again: President Trump's Trade War Could Have Ended Badly" on pp. 17 through 21. We're doing a fair use and transformative reading of the essay in one of my favorite publications. This is an engagement with an essay by Christopher Caldwell, one of my favorite writers on American Politics, The piece is accessible to the public at https://claremontreviewofbooks.com/lets-not-do-that-again/ Kesler, Editor of the CRB, was one of my Ph.D. professors at Claremont Colleges (4 courses). We want to thank Claremont Review of Books for making this material available. Go to ClaremontReviewofBooks.com to subscribe for a very reasonable price and get the hard copies with aesthetically pleasing artwork and thoughtful though accessible essays in your physical mailbox. The Republican Professor is a pro-Claremont-Review-of-Books podcast. The Republican Professor is produced and hosted by Dr. Lucas J. Mather, Ph.D.
Investing in Bizarro World Episodes: https://youtube.com/playlist?list=PLIAfIjKxr02sAztzlJNy1ug5bDvTVZkME&si=w2d_EF-B5jMo1dYDSubscribe to Investing In Bizarro World: @bizarroworld Editor's Note: The price for the premium version of Investing in Bizarro World is now $149 everywhere except this link: https://bit.ly/45I69sm The response to our final offer at $99 was so strong that we're keeping it open until we record the next live episode this Thursday. You might find it especially useful as Gerardo and I navigate what we're doing with precious metals volatility in real time. Last chance at $99 right here: https://bit.ly/45I69sm —NickThe free version of the 351st episode of Investing in Bizarro World is now published.Here's what was covered:Macro Musings - Nick and Gerardo open with on-the-ground observations from Vancouver, where packed conference halls, nonstop meetings, and companies actively competing to deploy capital underscored how strong sentiment has become across the metals and resources space. Despite some high-profile voices warning of froth, both agree this market is still structurally driven — not retail-led — with China standing out as a major physical buyer. Silver pricing is highlighted as a key signal: while trading near $117 per ounce in Western markets, physical silver in China was quoted closer to $146, underscoring the premium being paid for real metal. Gold and silver consolidations are getting shorter, the U.S. dollar has touched a four-year low near 96 on the DXY, and political pressure for lower rates is intensifying. The takeaway: this remains a bull market built on currency debasement, debt, and sovereign demand — but discipline matters more than ever.Market Takes - The conversation moves into volatility, technical levels, and how to navigate sharp moves without chasing. Gold recently surged from roughly $5,000 to $5,600 in a matter of days before consolidating near $5,400. Silver corrected to about $103 while Nick and Gerardo were in Vancouver before rebounding to $120 and settling around $116. Copper pushed through all-time highs above $6 per pound, with upside potential still intact even on pullbacks toward $5.75. Tin hit record highs near $53,000–$54,000 per tonne, aluminum reached four-year highs around $3,300 per tonne, platinum broke to new highs, and palladium moved to multi-year highs. Lithium carbonate rebounded to above $23,000 per tonne after trading near $8,000–$9,000 last summer. The broader CRB commodity index has broken out, signaling strength across the entire complex. Nick reiterates the importance of buy-under prices and limit orders, using Aldebaran Resources as a case study, where a $35 million financing at C$3.25 created a brief pullback to the C$3.60 buy-under level before shares rebounded.Bizarro Banter - The discussion turns somber as Nick and Gerardo reflect on global unrest and domestic events that are increasingly shaping capital flows. Firsthand observations from a massive, peaceful protest in Vancouver — estimated at 10,000–20,000 people — serve as a contrast to recent events in Iran and the United States. They recount personal conversations with individuals directly affected by communications blackouts and violent crackdowns abroad, then pivot to concerns about law enforcement conduct, constitutional rights, and the erosion of trust at home. The core theme is consistency: when institutions lose credibility and force replaces accountability, capital predictably migrates toward hard assets, jurisdictional safety, and tangible stores of value. The metals market is responding accordingly.Premium Portfolio Picks - For paid listeners only. (Though you get a free Q&A this week.) Subscribe here: https://bit.ly/49UPxAi0:00 Introduction3:15 Macro Musings: Vancouver Conference Froth. Shorter Metals Consolidations. China Physical Premium.7:06 Market Takes: Tether Gold Hoard. Buy-Under Limit Orders. CRB Breakout Setup.26:35 Bizarro Banter: Iran Protest March. Regime Blackout Stories. ICE Shooting Outrage.45:03 Premium Portfolio Picks: (You need to subscribe to Bizarro World Live to get this section)PLEASE NOTE: There are now two versions of this podcast. 1. Bizarro World Live — Pay $2 per episode to watch us record the podcast live every Thursday and get Premium Portfolio Picks every week. Plus an archive of all premium episodes. Subscribe here: https://bit.ly/49UPxAi2. Bizarro World Free — Published the Monday after the live recording with no Premium Portfolio Picks.Visit our website Daily Profit Cycle for more content like this and more! https://dailyprofitcycle.com/
Claremont Review of Books published an issue in Summer 2025 where the question is posed on the cover, decorated by attractive art, "Will there always be an England?" We're doing a fair use and transformative reading of an essay in one of my favorite publications. This is an engagement with an essay by Christopher Caldwell, one of my favorite writers on American Politics, entitled "Land's End" in Summer 2025 Claremont Review of Books pp 8-12. The piece is accessible to the public at https://claremontreviewofbooks.com/lands-end-2/ It's the second piece in CRB history to have that title . Kesler, Editor of the CRB, was one of my Ph.D. professors at Claremont Colleges (4 courses). We want to thank Claremont Review of Books for making this material available. Go to ClaremontReviewofBooks.com to subscribe for a very reasonable price and get the hard copies with aesthetically pleasing artwork and thoughtful though accessible essays in your physical mailbox. The Republican Professor is a pro-Claremont-Review-of-Books podcast. The Republican Professor is produced and hosted by Dr. Lucas J. Mather, Ph.D.
We cover immigration today with Mark Krikorian's excellent short book review in Claremont Review of Books, Spring 2025 on page 16 of the physical print edition you get in the mail four times a year when you subscribe for a nominal charge. We do a fair use and do a transformative reading of this material. We'd like to thank Claremont Review of Books for making this material available. We'd like to thank Mark Krikorian for writing it. As of the day of recording, the piece was available to the public on the website. Just go to the website and search "Mi Casa" and follow along. But it's best to subscribe so you get the hard copies in the mail. I highly recommend that you support CRB. Subscribe today at https://claremontreviewofbooks.com/ You won't regret it. The Republican Professor is a pro-self-government podcast. The Republican Professor is produced and hosted by Dr. Lucas J. Mather, Ph.D.
There are lessons for American Political Development in poignant political phenomenology of Europe by Christopher Caldwell in Claremont Review of Books' Summer 2019 edition. We discuss his excellent piece, "Why Hasn't Brexit Happened ?" on the physical copy's pp. 33-42. We make a fair use and transformative reading of this material with application to American Political Development (APD). CRB has generously made this material available for you to follow along on their website. We want to thank Claremont Review of Books for making this material available. Go to ClaremontReviewofBooks.com to subscribe for a very reasonable price and get the hard copies with aesthetically pleasing artwork and thoughtful though accessible essays in your physical mailbox. The Republican Professor is a pro-Claremont-Review-of-Books podcast. The Republican Professor is produced and hosted by Dr. Lucas J. Mather, Ph.D.
Double Tap Episode 437 This episode of Double Tap is brought to you by: Gideon Optics, Blue Alpha, Medical Gear Outfitters, Bowers Group, Second Call Defense, and Matador Arms Welcome to Double Tap, episode 437! Your hosts tonight are Jeremy Pozderac, Aaron Krieger, Nick Lynch, and me Shawn Herrin, welcome to the show! Sponsor Black Friday Deals -Midwest Industries- 20% off MI products Code: STOCKUP25 Medical Gear Outfitters- 15% off. Free Ship over $75. Lots of special deals. Code MGO15 Primary Arms - https://www.primaryarms.com/firearms-black-friday-sale Dear WLS Phillip C - Hello gentlemen, And Aaron, brc made my absolute favorite wallet! On my second one and been carrying an Oscar Mike wallet for over 5 years. My question is was brc making the nylon goods in house or was someone making the soft foods for them to stamp a rhino onto? Have looked all across the interwebs trying to find a similar wallet to no avail. Even reached out to the customer support email from past brc orders with no reply. Maybe something Flatline Fiber Co. Could spool up and start making.? I can't be the only one who would run naked backwards thru a cornfield to get my hands on a few more Oscar Mike wallets. Thank you. Keep your powder dry. And shoot straight. #WLSISLIFE No notes Alex W - Just saying. When Shawn says Die Free Co. It sounds like hes saying "Die, freako!" Edward H - I need help deciding what to get I need a gun with a manuel saftey but I also want an external hammer with DA/SA ability, it to be in .45, and the ability to host a light and optic. Thanks Drew P - I want to get into long range shooting (1000+ yards)have my eye on a Ruger precision in 6.5 cm with a swamp fox scope, but it got me thinking what is the cheapest rifle and scope set up you could do? Could you get a set up for under $500? Lance D - You convinced to buy a chest rig from AceTac. Now, can we see your rigs and how you have them setup? Mine will be primarily used for larping/range use, and thought of using as kind of a “go bag” type setup. Thanks Scott G - Alright I I think the ace tac micro chest rig with the back pack is the closest to what I have been wanting for a day pack hunting/ hiking pack. It is missing 3 parts I think I can rig in to it but I'm looking for your advice as well. 1 I want to add a bino pouch to the chest rig , one of the set ups with a magnetic flip open top. 2 a holster for a G 19 x or G 17 my typical woods carry piece 3 water I am not a fan of bladders I like a Nalgene bottle. What does the cast think about those issues ? Nate D - Has Anyone Really Been Far Even as Decided to Use Even Go Want to do Look More Like? Harry H - What are in your opinion the best magazine? Double stack pistol Single stack pistol Ppc/smg Ar15 Bolt action Maybe give brand/model name. I have always heard pmag for ar15 but is that m2 or m3. Just a example. The winner of this week's swag pack is Alex W! To win your own, go to welikeshooting.com/dashboard and submit a question! Gun Industry News AGM Launches New Mini 4K Day/Night Scope AGM Global Vision released the Spectrum 4K-Mini, a lightweight digital day/night scope weighing 16 ounces, perfect for hunters who want mobility without losing image quality. It features a 4K ultra-HD sensor, color imaging by day, and black-and-white viewing at night, plus recording and connectivity options. This scope is simpler to use and mount compared to larger models. It costs $895 and is available now. New Compensators: Strike Industries XLogic Warpath and Mini Warpath Strike Industries launched two new compensators for .223/5.56 AR-15s called the Warpath Comp and Mini Warpath Comp. The Warpath Comp has two side ports and one top port, while the Mini has one side port and one top port. The Mini is designed to cut felt recoil by over 25%. The Mini Warpath Comp costs $51.95. Both products are currently available. Beretta's New AX800 Suprema Shotgun for Waterfowl Hunting Beretta launched the AX800 Suprema, a new semi-automatic shotgun for waterfowl hunters. It features a fast and clean B-LINK Pro gas system, Steelium Pro barrels for consistent patterns, and a Kick-Off Pro recoil reduction system. The shotgun is designed for tough weather and can be easily adjusted to fit different shooters. Prices are not specified. It will start shipping in December 2025. New 10mm Trapper Lever Gun from Marlin Marlin just released the 10mm Trapper lever gun, a first for this brand. It features stainless steel construction, a 16-inch barrel, and can hold 10 rounds of 10mm Auto. It has a peep sight and is not compatible with .40 S&W ammo. The price is $1,599, and it's available for purchase now. Affordable Micro-Compact Pistol with High Capacity Derya Arms released the DY9Z, a new striker-fired 9mm micro-compact pistol priced at $299. It has a small size for easy concealment and holds 15 rounds. The slide is ready for optics, and it comes in ten different colors. It includes a metal magazine catch to work seamlessly with the Glock 43X and PSA Micro Dagger. The DY9Z is designed for concealed carry, home defense, and recreational shooting. It's available now. New Volquartsen Mini Mamba-TF Rimfire Pistol Review Volquartsen Firearms and Davidson's released an exclusive FDE Mini Mamba-TF, a lightweight .22 LR pistol. It's designed for suppressors, measuring over 8 inches and weighing about 1 pound 12 ounces. The pistol has a 3-inch stainless steel barrel, Picatinny rail for optics, and comes with special Earth Camo grips. It costs $1,575.99 and is only available through Davidson's Gallery of Guns. SIG Sauer's Latest Rifle: The SIG516 G3 SIG Sauer has launched the SIG516 G3, a new rifle designed for tough use. It features a short-stroke piston, adjustable gas system, and is chambered in 5.56 NATO. The rifle has a 16-inch barrel, ambidextrous controls, and durable materials for long life. It's built for reliability and versatility. Pricing information isn't available yet. The rifle is currently not available. Flux Defense Launches Super Light PDW for Defense Flux Defense launched the P365 Ultra-Light Chassis System, a new Vehicle Defensive Weapon (VDW). It makes the Sig P365 much lighter and more compact, fitting easily in small spaces like gloveboxes. It can hold up to 50 rounds with extensions, weighs only 8.7 ounces, and comes with a flexible 2.0 adjustable holster. It enhances speed, accuracy, and control, making it different from other weapons. The product is currently available for purchase. O P Tactical Expands with New Carcajou Product O P Tactical is now offering products from Carcajou Tactical, a Canadian brand known for high-quality gear like the NVG Skull Harness. Items are in stock and ready to ship. New KRISS Vector Gen 3 Guns in Cool Colors KRISS USA is now shipping new color variants, Alpine and Flat Dark Earth, for the KRISS Vector Gen 3. These colors are available for the Carbine, Pistol, and Short-Barreled Rifle models. The upgrade service for Gen 2 owners will start in January 2026. Prices are $1,499.99 for the SDP, $1,749.99 for the CRB, and $1,699.99 for the SBR. The product is available now. MDT Introduces New Elite Bag Rider MDT has launched the Elite Bag Rider, a tool for precision shooters that helps improve stability and control when aiming. It has options for different shooting styles and is made from strong aluminum. The bag rider connects to several MDT buttstocks and offers adjustments for better support. It is designed to provide a smooth and snag-free shooting experience. The product is available now. Before we let you go - Join Gun Owners of America Tell your friends about the show and get backstage access by joining the Gun Cult at theguncult.com. No matter how tough your battle is today, we want you here fight with us tomorrow. Don't struggle in silence, you can contact the suicide prevention line by dialing 988 from your phone. Remember - Always prefer Dangerous Freedom over peaceful slavery. We'll see you next time! Nick - @busbuiltsystems | Bus Built Systems Jeremy - @ret_actual | Rivers Edge Tactical Aaron - @machinegun_moses Savage - @savage1r Shawn - @dangerousfreedomyt | @camorado.cam | Camorado
Oral Arguments for the Court of Appeals for the D.C. Circuit
Music Choice v. CRB
Building on insights from CRB's Horizons: Life Sciences 2025 report, this second installment of our conversation with Peter Walters, Fellow of Advanced Therapies at CRB, explores the modalities driving forward momentum across the life sciences industry, the expanding role of standardization in manufacturing networks, and how tariffs and domestic investment strategies are shaping the future of pharma manufacturing. If you missed Part One, catch our discussion on the rise of continuous manufacturing and its growing adoption across large pharma.
Coach Birks of the Autobahn Wheelers recap their 7-0 season after an 86-30 road win at Coon Rapids-Bayer, highlighting a dominant varsity performance and key JV contributions. The episode covers Aiden Kiergaard's multi-touchdown explosion, big special teams plays (including a punt return TD), and how the team adjusted after early long runs by CRB. Coach previews senior night against a close rival and reflects on the strength and depth of eight-man football across the state.
Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma e Biotech world.Zenas has made a $2 billion bet on autoimmune diseases with Chinese firm InnoCare, focusing on the development of orelabrutinib for multiple sclerosis. Former FDA director Peter Marks has joined Eli Lilly, marking the company's continued push in China. Sanofi's advancements in radiopharma, Boehringer Ingelheim's breakthrough in idiopathic pulmonary fibrosis, and Takeda's exit from cell therapy are also top stories. Cytiva filtration is highlighted as a solution for maintaining product integrity in biopharma.Biospace profiles the five most powerful women leading smaller biopharmaceutical companies, as the industry sees a shift with the departure of GSK CEO Emma Walmsley. A survey by CRB reveals that most life sciences companies are not planning new investments after tariffs, with big pharma taking the lead in manufacturing initiatives. Drug pricing criticism often overlooks the dynamic nature of drug pricing over time. Takeda's journey in building a cell therapy portfolio, only to ultimately walk away, is explored. Pfizer wins the bid for Metsera, Amgen offers Repatha at a discounted rate, and Roche acquires Akero for $3.5 billion. Biospace also honors 40 under 40 winners making an impact in the industry.Peter Marks, former director of the FDA's Center for Biologics Evaluation and Research, has taken on a new role as Senior Vice President for molecule discovery and the head of infectious diseases at Eli Lilly. Marks' controversial exit from the FDA led to his hiring by Lilly, following in the footsteps of another former FDA official, Rachael Anatol. Marks confirmed his new role to Stat News and began his first day at Lilly Research Laboratories on Monday.Support the show
Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.A new survey from CRB shows that most life sciences companies, particularly smaller biotechs, are not planning new investments in response to tariffs. The majority of manufacturing initiatives in the U.S. made in response to tariffs are coming from big pharma companies. Sky Bioscience's CB1 inhibitor, Nimacimab, showed promising weight-loss results when combined with Wegovy despite falling short of expectations in a mid-stage obesity trial. Amgen will offer its lipid-lowering drug Repatha directly to patients at a 60% discount. Biospace has honored 40 under 40 leaders in biopharma whose achievements reflect the industry's grit and impact. Pfizer beat out two other suitors for a takeover of Metsera. Maplight seeks a $227 million IPO for its neuropsych portfolio.AMT designation is taking its first steps amid uncertain benefits. Pharming's restructuring triggers a 20% reduction in its workforce. Experts are forging new paths to address scalability, cost, and other barriers surrounding cell therapy production.The CDC has adopted ACIP recommendations on chickenpox and COVID-19 vaccines. Stay tuned for upcoming events such as webinars on mRNA medicine, biopharma deregulation, and transforming digital sequences into mRNA.Various job opportunities in the life sciences industry include positions at Sonothera, Eli Lilly and Company, and Amgen.Support the show
The U.S. government is now in its second week of a shutdown—with the FDA having paused acceptance of all new drug applications for the duration. But it was business as usual at the CDC, which adopted the recent recommendations of its newly revamped advisory committee on chickenpox and COVID-19 vaccines. And another senior leader, National Institute of Allergy and Infectious Diseases Director Jeanne Marrazzo, was fired last week, after filing a whistleblower report. Across the country, cell and gene therapy leaders arrived in Phoenix for the annual Meeting on the Mesa, as the space remains in a state of flux—with regulatory and M&A momentum being stalled by commercial and market challenges. Takeda, for one, is looking to offload its cell therapy platform after years of hefty investment. President Donald Trump's long-awaited tariffs did not hit on Oct. 1 as promised. But in the face of the looming levies, Pfizer signed a drug pricing deal with the White House that provides a three-year exemption. Amgen appears to be climbing onboard as well, announcing that its lipid-lowering drug Repatha will be available at a steep discount. These moves are all well and good for Big Pharma players, but a recent report from CRB reveals most smaller biopharma companies are not planning any investments to offset tariffs. In our weekly weight loss segment, Skye Bioscience's cannabinoid receptor 1-targeting candidate nimacimab failed to outpace placebo in reducing body weight but elicited “intriguing synergy” in combination with Novo Nordisk's Wegovy, according to William Blair analysts. And regulatory documents shed further light on Pfizer's $4.9 billion takeover of Metsera, in which the New York pharma beat out two higher bidders for the promising obesity startup. Finally, make sure to check out The 5 Most Powerful Women in Biopharma and BioSpace's inaugural 40 Under 40, highlighting 40 young leaders who have made an impact on the biopharma industry.
Based on insights from CRB's Horizons: Life Sciences 2025 report, this episode of Off Script: A Pharma Manufacturing Podcast features a conversation with Peter Walters, Fellow of Advanced Therapies at CRB. Walters discusses how the industry is advancing toward continuous manufacturing, highlighted by a key finding from the report — 65% of large companies are pursuing end-to-end continuous manufacturing. This is part one of a two-part series. In part two, dropping Oct. 14, 2025, Walters will return to explore advanced therapies, tariffs, and regulatory changes shaping the global pharma manufacturing landscape.
"Digital twins are still solving problems we haven't even imagined yet."In today's episode of Bricks, Bucks & Bytes, we had James Mize from CRB and we got to learn about why pharmaceutical and biotech construction is pushing the boundaries of what's possible with digital twins, the real reason most companies stick with their tech partners, and why information management is construction's biggest unsolved problem... and many more!Tune in to find out about:✅ How predictive maintenance using digital twins is saving pharmaceutical companies millions in downtime costs✅ Why design innovation is racing ahead while construction remains stubbornly manual✅ The partnership model that actually works when choosing construction technology vendors✅ Why document control might disappear completely as AI learns where every file should liveListen now on Spotify and join the conversation about the future of construction technology.----------Our Sponsor: Archdesk - “The #1 Construction Management Software for Growing Companies - Manage your projects from Tender to Handover” check archdesk.comBuildVision - streamlining the construction supply chain with a unified platform - www.buildvision.io-------------------Chapters00:00 Intro03:05 Exploring Digital Twins in Construction09:10 The Role of CRB in Biotech and Pharmaceutical Construction14:54 Innovation in Design vs. Construction20:50 Evaluating Technology Vendors and Solutions26:43 Navigating Pricing Models for Tech Solutions36:31 Exploring Software Innovations in Construction38:34 Identifying Pain Points in Information Management43:04 Researching Solutions: Inbound vs Outbound47:18 Evaluating Information Management Tools51:42 Lessons from Technology Failures54:11 The Role of Venture Backing in Technology Solutions55:09 Importance of Construction Experience in Founders56:39 Contrarian Views on External Validation57:41 Gathering Feedback from the Field01:00:04 Maximizing ROI from Technology Investments01:02:00 Current Initiatives and Hiring Opportunities
This is part 2 of 2 of a fair use and transformative reading of an essay in one of my favorite publications. This is an engagement with an essay by Dr. William Voegeli, one of my favorite writers on American Politics, entitled "Now What? The Democrats After 2024" in Winter 2025 Claremont Review of Books pp -8-14, going from the bottom of p. 9 in the print edition through page 14.. The piece is accessible to the public at https://claremontreviewofbooks.com/now-what/ Kesler, Editor of the CRB, was one of my Ph.D. professors at Claremont Colleges (4 courses). We want to thank Claremont Review of Books for making this material available. Go to ClaremontReviewofBooks.com to subscribe for a very reasonable price and get the hard copies with aesthetically pleasing artwork and thoughtful though accessible essays in your physical mailbox. This episode includes a reading from the 1925 edition of "Streams in the Desert", January 2nd. The Republican Professor is a pro-Claremont-Review-of-Books, pro-correctly contemplating-contemporary-American-Politics, pro-Streams-in-the-Desert-original-edition-from-1925 podcast. The Republican Professor is produced and hosted by Dr. Lucas J. Mather, Ph.D.
Episode 94: Show Notes How do you know if a building lives up to its claim of being well-maintained, professionally managed, and with a quality-living offering? That's where the Certified Rental Building Program (CRB Program) comes in. We are joined today by Dilan Cetinkaya, the Director of Certification at the Federation of Rental-Housing Providers of Ontario (FPRO), the leading advocate for strong and stable rental housing and the largest association in Ontario representing those who own, manage, build, finance, service, and supply residential rental homes. At FPRO, Dilan oversees all certification standards for the Canadian Certified Rental Building Program (CRBP), and she begins our conversation by detailing the work and main focuses of CRBP. We learn about the pain points the CRB Program is trying to solve, how it separates itself from other quality claims or qualifications, the standards that need to be met to obtain CRB certification, and how long it takes to get certified. Dilan also explains how the program helps landlords and property managers compared to renters before unpacking the CRBP's green initiative, Living Green Together. To end, our guest walks us through a step-by-step guide to becoming CRB certified, and we learn what the future may hold for the CRBP and its work. Key Points From This Episode: The Canadian Certified Rental Building Program (CRBP) and Dilan Cetinkaya's role at the organisation. Why the Certified Rental Building Program (CRB Program) was created; pain points it aims to solve. How the CRB Program differentiates itself from other past quality claims or qualifications? The standards buildings are required to meet to become CRB Program certified. Understanding the frequency of accountability checks and how long it takes to be certified. How the CRB Program helps landlords and property managers versus how it helps renters. Case studies that highlight the program's impact on tenant satisfaction and retention. Living Green Together: Unpacking the CRBP's green initiative. Dilan explains how the program will make rental searches easier moving forward. A step-by-step guide to becoming CRB certified. What the CRBP has planned for its future and what tomorrow may hold for the CRB Program. How to find CRB-certified buildings in your rental search. Quotes: “For owners and managers, [the CRB Program] helps to ensure that your property is reducing its operational costs, mitigating risks, and improving asset performance. For renters, it essentially provides a stamp that this building is well-run, well-managed, [and] well-maintained.” — Dilan Cetinkaya [0:02:04] “By being CRB certified, you do get additional [ESG] points. We are recognized by [Global Real Estate Sustainability Benchmarking] and we're an industry supporter. So, you're also helping to improve your ESG performance as well.” — Dilan Cetinkaya [0:10:39] “Overall, I just think [the CRB Program] will help make the rent search easier for residents.” — Dilan Cetinkaya [0:16:52] Links Mentioned in Today's Episode: Dilan Cetinkaya on LinkedIn Dilan Cetinkaya Email Canadian CRB Program (CRBP) Federation of Rental-housing Providers of Ontario (FRPO) BOMA BEST RentSafeTO Rentals.ca Rentsync Sync or Swim Podcast Sync or Swim Email
We're doing a fair use and transformative reading of part of an essay in one of my favorite publications. This is an engagement with an essay by Dr. William Voegeli, one of my favorite writers on American Politics, entitled "Now What? The Democrats After 2024" in Winter 2025 Claremont Review of Books pp 8-9. The piece is accessible to the public at https://claremontreviewofbooks.com/now-what/ Kesler, Editor of the CRB, was one of my Ph.D. professors at Claremont Colleges (4 courses). We want to thank Claremont Review of Books for making this material available. Go to ClaremontReviewofBooks.com to subscribe for a very reasonable price and get the hard copies with aesthetically pleasing artwork and thoughtful though accessible essays in your physical mailbox. This episode includes a reading from the 1925 edition of "Streams in the Desert", January 1st. The Republican Professor is a pro-Claremont-Review-of-Books podcast. The Republican Professor is produced and hosted by Dr. Lucas J. Mather, Ph.D.
Chegou o tradicional Raio X da Série B! A gente avisou… e o Criciúma chegou! O Tigre ganhou 11 posições em 8 rodadas e entra no G4. Analisamos também as campanhas de Athletico, CRB, Goiás, Coritiba, Remo, América-MG e muito mais. No programa, o já tradicional trio formado por Fred Figueiroa, Cássio Zirpoli e Hathos […]
Brasileirão ou Copa do Brasil? Qual competição o time de priorizar? CRB foi mais difícil que o esperado? Cássio vive melhor fase na Toca? E os reforços? Porta de saída vai ser mais movimentada que a de entrada? Com Fábio Júnior, Fernanda Hermsdorff, Guilherme Macedo e Rodrigo Franco
Cantor Silverstone visits Rotem and Ta'am the studio and talks about the history of camp when he was a camper at CRB!
Estratégia de mesclar a equipe está atrapalhando? Favoritismo contra o CRB segue intacto? Onde buscar o driblador pedido pelo técnico Leonardo Jardim? Com Gabriel Duarte, Fernanda Hermsdorff, Henrique Fernandes e Rogério Corrêa. A edição é de Raquel Vieira. Dá o play!
Primeira derrota em casa no Brasileirão foi só um acidente? Resultado inesperado no jogo com o Ceará fará o Cruzeiro atuar melhor contra o CRB, na Copa do Brasil? Qual é o destino mais provável do artilheiro Kaio Jorge: a Europa ou a Seleção? Com Rodrigo Coutinho, Danny Paiva, Fernanda Hermsdorff e Rogério Corrêa. Edição: Lavínia Aguiar.
Chegou mais um Raio X da Série B do Campeonato Brasileiro. Todas as análises após a 15ª rodada. Um novo Líder, onde tudo podde acontecer, quedas de CRB e Cuiabá, farrapada do América-MG, reação a comentários, odds Betnacional e muito mais! Apresentação de Fred Figueiroa com comentários de Cássio Zirpoli e Hathos Rildo. Na edição, […]
We're continuing our fair use and transformative reading of the rest of an essay in one of my favorite publications. This is an engagement with an essay by TRP podcast guest Charles R. Kesler and one of my favorite writers on American Politics entitled "America's Red Shift" in Fall 2024 Claremont Review of Books. Kesler was also one of my Ph.D. professors at Claremont Colleges (4 courses). We pick up reading and commenting at "Kamala's Red Shift" on page 8, continuing to the end on page 12 in the hard cover edition. CRB has generously made this material available for you to follow along on their website. We want to thank Claremont Review of Books for making this material available. Go to ClaremontReviewofBooks.com to subscribe for a very reasonable price and get the hard copies with aesthetically pleasing artwork and thoughtful though accessible essays in your physical mailbox. The Republican Professor is a pro-Claremont-Review-of-Books podcast. The Republican Professor is produced and hosted by Dr. Lucas J. Mather, Ph.D.
Voltamos no embalo do forró! Depois de um mês sumidos, voltamos com pé no São João pra falar do futebol nordestino que não para – nem quando a Série A tira férias pra ver o Mundial da FIFA! Na Série B, o CRB meteu o pé na porta e detonou o líder lá no Rei Pelé!Na Série C, o CSA tá surpreendendo e firme no G8. Já Belo, Confiança e Itabaiana estão que nem fogueira molhada.Na Série D, finalmente o Santa Cruz deu alegria pro torcedor! Já o Sousa... decepcionando como sempre. E Ciel? 43 anos e artilheiraço na ativa.
O Bate-Pronto de hoje falará tudo sobre o retorno de Neymar aos gramados. O craque jogou cerca de 25 minutos contra o CRB, deu bons passes, converteu um dos pênaltis do Peixe, mas viu o time alvinegro ser eliminado da Copa do Brasil nas penalidades após empate sem gols fora de casa. O programa também repercutirá a vitória do Palmeiras sobre o Ceará por 3 a 0, projetará o jogão da equipe alviverde contra o Flamengo pelo Brasileirão e muito mais!
O Santos está eliminado da Copa do Brasil. O Peixe perdeu para o CRB, nos pênaltis, e se despediu da competição. Neymar voltou a jogar, mas não conseguiu evitar o vexame santista em Maceió. Neste episódio, Bruno Gutierrez e Nágila Luz comentam o desempenho do time em campo e os desdobramentos por conta da eliminação. Além disso, o futuro de Neymar no Santos, a pressão em cima do técnico Cléber Xavier, as críticas a gestão do clube e o que esperar do jogo contra o Vitória, pelo Campeonato Brasileiro. Dá o play para ficar por dentro de tudo isso e muito mais!
Today: A music panel highlighting some great local events and artists, from the Newport Folk Festival to the jazz offerings around town. We talk with Brian McCreath of CRB, James Bennett II of GBH News, and Berklee's Emmett Price.
O Santos perdeu para o Corinthians e segue na penúltima colocação do Campeonato Brasileiro. Em crise, o Peixe não vence uma partida desde que bateu o Atlético-MG, em 16 de abril. A pressão por resultados aumenta, com o time tendo uma decisão na Copa do Brasil pela frente. Neste episódio, Ana Canhedo, Bruno Gutierrez e Nágila Luz analisam a atuação do Peixe. Além disso, a provável volta de Neymar no duelo contra o CRB, na quinta-feira, pela Copa do Brasil e a necessidade de reforços para a sequência da temporada. Dá o play para ficar por dentro de tudo isso e muito mais!
No pós-jogo de hoje, comentamos a vitória do Sport sobre o CRB por 2 a 1, que garantiu a classificação antecipada do Leão da Ilha para a próxima fase da Copa do Nordeste! Com uma atuação de destaque de Sérgio Oliveira, o volante português foi fundamental para o triunfo rubro-negro. Ele deu uma assistência precisa […]
BillieTheGoat pulls up for a convo - DMs Fanum from AMP, partying with the Sidemen, and breaking down the most unhinged streams. From gaming and dating advice to random chats about pickles and CRB checks.Listen to the FULL PODCAST and follow us on:Spotify - https://open.spotify.com/show/4UjhcQP...Apple Podcasts - https://podcasts.apple.com/us/podcast...Tiktok - https://www.tiktok.com/@chloevsthewor...Instagram - https://www.instagram.com/chloevsthew...Chloe: https://www.instagram.com/chloeburrows/?hl=enDilemmas: chloevstheworldsubmissions@gmail.com
With a new administration in office, speculation is running high on what the future holds for financial institutions working within the cannabis-related business (CRB) industry.Today's guest is Kevin Gulledge, Senior Risk Management Consultant at Abrigo and a seasoned expert in financial compliance. With extensive experience guiding banks and credit unions through the challenges of serving CRBs, Kevin brings valuable insight into the regulatory and operational hurdles financial institutions face.In this episode, we'll break down the current speculation surrounding cannabis banking under the new administration, what we're hearing from bankers on the front lines, and any proposals in the pipeline that could impact financial institutions. Plus, we'll explore the unknowns—those lingering uncertainties that could shape the future of CRB banking.Helpful links:CRB insights webpage: MJBizDaily | Cannabis Industry Financial & Legal NewsPodcast: Banking on cannabis: Breaking down the SAFER Banking Act Whitepaper: Providing financial services to cannabis-related businessesBlog: Cannabis lending for financial institutions: Best practices
Today:We reconvene our music panelists ahead of Sunday's Grammy Awards. Almost everybody knows about Beyonce and Sabrina Carpenter, but with help from CRB's Brian McCreath, Berklee's Emmett G. Price III, and GBH's James Bennett II, we hear about some nominees you may have missed.
Ceará vai até Recife e perde para o náutico em partida com gol único. CRB recebe o Vitória, com partida marcada pela competitividade e placar com 4 gols e sai no empate. Sport vai até Fortaleza, no PV, e vence o Ferroviário com gol marcado no ultimo minuto. Todas as análises das partidas dessa super live […]
Colt and David sit down with David Israelite. David is President and CEO of the National Music Publishers' Association (NMPA), a position he has held since February 2005. Israelite is responsible for overseeing all aspects of NMPA's operations, from legal strategy and implementation to government affairs and advocacy. His leadership has produced revolutionary successes on behalf of publishers including the largest CRB rate increase in history, groundbreaking industry collaboration in royalty rate agreements, landmark settlements and model licenses with streaming platforms, and ultimately raising the profile of the publishing community. Additionally, Israelite was instrumental in guiding the effort to modernize copyright laws culminating in the Music Modernization Act (MMA) and the subsequent creation of the Mechanical Licensing Collective (MLC).Website: www.nmpa.orgFacebook: www.facebook.com/disraeliteInstagram: www.instagram.com/disraeliteTwitter (X): www.twitter.com/davidisraeliteSend us a textSupport the showCheck out our socials and follow us!Facebook: www.facebook.com/TwangTownPodcastInstagram: www.instagram.com/TwangTownPodTwitter: www.twitter.com/TwangTownPodWe would love your support to continue to bring listeners amazing content!Cash App: www.cash.app/$TwangTownPodBuzzsprout: https://www.buzzsprout.com/2232176/support
On today's Friday News Roundup, it's acronym day! District 25 Metro Council member Jeff Preptit joins host Marie Cecile Anderson and executive producer Whitney Pastorek to give us his take on Tuesday's council meeting, where MNPD's contract with surveillance tech company FUSUS was deferred once again after a passionate public hearing. We're also talking about the CRB's new MOU with MNPD, the Mayor's $527 million proposed CSP, and with sunset now at 4:30 p.m., how we're managing our SAD. Not sure what any of those letters mean? We've got you covered. Learn more about Alex Wong and his new album, “Permission.” Want some more City Cast Nashville news? Then make sure to sign up for our Hey Nashville newsletter. Follow us @citycastnashville You can also text us or leave a voicemail at: 615-200-6392 Interested in advertising with City Cast? Find more info HERE. Learn more about the sponsor of this Nov. 21st episode: Tecovas
NBC political director Chuck Todd returns for his weekly D.C. news roundup. Then we open the phone lines for a potpourri politics discussion. The GroundTruth Project's Charlie Sennott talks about the implications of Trump's win on the global stage. MIT economist Jon Gruber explains what could happen to healthcare and healthcare costs under another Trump presidency. (Jon was central in creating the Affordable Care Act during the Obama administration). CRB's Brian McCreath, Rev. Emmett G. Price III & James Bennett II return for a quarterly music panel, running through some great live music coming to Boston and reflecting on the passing of Roy Haynes & Quincy Jones. And we hear from listener's about their love for Trader Joe's and other grocery stores.
Today: Andrea Cabral fills in for Jim.Charlie Sennott of The GroundTruth Project discusses the Christian Zionist in Trump's cabinet, Mike Huckabee -- he was just named Ambassador to Israel.And we hear from CRB's Brian McCreath, Berklee College of Music's Rev. Emmett Price, and GBH's culture reporter James Bennett II about local concerts coming up.
Welcome back to an all-new episode of State of Amorica! This week, we are very pleased to welcome none other than Adam MacDougall! Adam sits down with David, Ian and guest host Ryan Oleskey to discuss his time in the Crowes and the CRB, plus his current happenings with Circles Around the Sun and a special new project he has in the works. Check it out!
O Sport está de volta ao G-4 da Série B! Depois de uma grande queda de rendimento, o Rubro-negro reencontrou o bom futebol e voltou a vencer em seus domínios. O Leão derrotou o CRB por 2 x 0, com show do meia Lucas Lima. O atleta foi o grande nome da partida, com um gol marcado e uma assistência […]
Stop Talking, Take Action, Get Results. Business and Personal Growth with Jen Du Plessis
This week join Jen and guest John Mayfield. John shares with Jen how crucial it is to keep the fundamentals, the basics in the real estate world. Listen to hear more about it! ____________________ Join the Mortgage Lending Mastery Community Today: YouTube: https://www.youtube.com/channel/UCIz6-AkN3rMajV8OHfbJ_zw?view_as=subscriber Facebook: https://www.facebook.com/JenDuPlessis22 Instagram: https://www.instagram.com/jenduplessis/ Website: www.JenDuPlessis.com LinkedIn: https://www.linkedin.com/in/jenduplessis/ LinkedTree: https://linktr.ee/jenduplessis Interested in joining the Marketer's Cruise? Go to https://marketerscruise.com/ make sure you scroll down and find my name as your referral when booking. Book a Strategy Call with Jen TODAY: www.ChatwithJen.com _________________________ About John Mayfield John Mayfield received his real estate license in 1978 at the age of 18. John has been a practicing broker since 1981 and has owned and operated as many as three offices in Southeast Missouri during his real estate career. John has taught pre and post license real estate courses since 1988. John has earned the ABR®, ABRM, CRB, CIPS, e-PRO®, GRI, RENE, (Real Estate Negotiation Expert) Military and SRS designations throughout his real estate tenure. John is also a 2015 Graduate from REALTOR® University's Master of Real Estate Program, and recipient of the Capstone Award for his thesis paper. John has earned both REALTOR-Associate and REALTOR of the Year from his local board and received the 2014 Richard A. Mendenhall Leadership award from Missouri REALTORS and the REBI Hall of Leaders Award in San Francisco, CA at the NAR Conference. In 2020, John received the prestigious DREI (Distinguished Real Estate Instructor) from the Real Estate Educators Association. John has spoken to thousands of real estate professionals in over 25 countries throughout his speaking career. He is the author of eight books and creator of the “5- Minutes Series for Real Estate Agents,” Cengage Learning, with over 25,000 copies sold. He is the co-author of “21 Mistakes Real Estate Brokers Make and How to Avoid Them,” Acclaim Press with Corky Hyatt. John is also active on a local, state and national level for the REALTORS® Association, and served as the 2010 President of the CRB Council of Real Estate Brokers and Managers. John is Liaison for the National Association of REALTORS® to Greece, Serbia and Bulgaria and the Missouri REALTORS President. John has two children, Alex and Anne, and he and his wife Kerry live in Farmington, Missouri, where John owns and operates a virtual real estate firm, an online real estate school, Global Real Estate School, and speaks full-time around the U.S. and internationally. Learn more about your ad choices. Visit megaphone.fm/adchoices