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Melvyn Bragg and guests discuss the most abundant lifeform on Earth: the viruses that 'eat' bacteria. Early in the 20th century, scientists noticed that something in their Petri dishes was making bacteria disappear and they called these bacteriophages, things that eat bacteria. From studying these phages, it soon became clear that they offered countless real or potential benefits for understanding our world, from the tracking of diseases to helping unlock the secrets of DNA to treatments for long term bacterial infections. With further research, they could be an answer to the growing problem of antibiotic resistance.With Martha Clokie Director for the Centre for Phage Research and Professor of Microbiology at the University of LeicesterJames Ebdon Professor of Environmental Microbiology at the University of BrightonAnd Claas Kirchhelle Historian and Chargé de Recherche at the French National Institute of Health and Medical Research's CERMES3 Unit in Paris.Producer: Simon TillotsonIn Our Time is a BBC Studios Audio ProductionReading list: James Ebdon, ‘Tackling sources of contamination in water: The age of phage' (Microbiologist, Society for Applied Microbiology, Vol 20.1, 2022) Thomas Häusler, Viruses vs. Superbugs: A Solution to the Antibiotics Crisis? (Palgrave Macmillan, 2006)Tom Ireland, The Good Virus: The Untold Story of Phages: The Mysterious Microbes that Rule Our World, Shape Our Health and Can Save Our Future (Hodder Press, 2024)Claas Kirchhelle and Charlotte Kirchhelle, ‘Northern Normal–Laboratory Networks, Microbial Culture Collections, and Taxonomies of Power (1939-2000)' (SocArXiv Papers, 2024) Dmitriy Myelnikov, ‘An alternative cure: the adoption and survival of bacteriophage therapy in the USSR, 1922–1955' (Journal of the History of Medicine and Allied Sciences 73, no. 4, 2018)Forest Rohwer, Merry Youle, Heather Maughan and Nao Hisakawa, Life in our Phage World: A Centennial Field Guide to Earth's most Diverse Inhabitants (Wholon, 2014)Steffanie Strathdee and Thomas Patterson (2019) The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug: A Memoir (Hachette Books, 2020)William C. Summers, Félix d`Herelle and the Origins of Molecular Biology (Yale University Press, 1999)William C. Summers, The American Phage Group: Founders of Molecular Biology (University Press, 2023)
Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comThis week on the podcast Mikki welcomes back Dr. Guillaume Millet, to discuss sex differences in ultra endurance events. They discuss the interplay between biology and behaviour, how females are different from men and what possible advantages (and disadvantages) this may have over the longer distance. They also discuss biomechanics, and how much of this differences in the performance may be due to sociological differences. They discuss a ton, including Guillaumes dream event where true sex differences could be put to the test if money was no object!PhD, is a professor at Jean Monnet University in Saint-Etienne.From 1998 to 2013, he held various academic positions in France, including a 4-year full-time research contract at the French National Institute for Medical Research (INSERM).In 2013, he moved to the University of Calgary where he directed a research team of ~15 trainees, the Neuromuscular Fatigue Lab. He also was Vice-Chair Research of the Canadian Society for Exercise Physiology from 2014 to 2016.Back to France in 2018, he received a very competitive IDEXLYON fellowship (1,16 million €), a program that aims to attract outstanding scientists with a strong international track record and now leads the ActiFS (Physical Activity, Fatigue, Health) academic chair.Prof. Millet was named at the Institut Universitaire de France as a Senior member in 2019 and director of the inter-university Laboratory of Human Movement Biology in 2020.His general research area investigates the physiological, neurophysiological and biomechanical factors associated with fatigue, both in extreme exercise and in patients (neuromuscular diseases, cancer, ICU). His research is focusing on understanding fatigue in order to create tailored rehabilitation programs for clinical populations in order to enhance patients' quality of life.In July 2021, he had published 5 books and 260 journal articles (cited > 10,700 times), his H index was 55. He has supervised 37 postdoctoral fellows and PhD students coming from 13 different countries and he served as an external reviewer for over 60 PhD candidates. Guillaume has been an invited speaker ~ 137 times in 17 different countries.Dr Millet's profile here: https://libm.univ-st-etienne.fr/en/research-teams/paf/researchers/millet-guillaume.html Research gate https://www.researchgate.net/profile/Guillaume-Millet-3 Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwillidenCurranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk ooff your first order
Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comThis week on the podcast Mikki speaks to Guillaume Millet about the endurance athlete. They discuss factors which determine success, how important VO2 max is for someone going long, Guillaume's flush model and what creates fatigue, how we might train to be better athletes and build resilience against fatigue.Dr. Guillaume Millet, PhD, is a professor at Jean Monnet University in Saint-Etienne.From 1998 to 2013, he held various academic positions in France, including a 4-year full-time research contract at the French National Institute for Medical Research (INSERM).In 2013, he moved to the University of Calgary where he directed a research team of ~15 trainees, the Neuromuscular Fatigue Lab. He also was Vice-Chair Research of the Canadian Society for Exercise Physiology from 2014 to 2016.Back to France in 2018, he received a very competitive IDEXLYON fellowship (1,16 million €), a program that aims to attract outstanding scientists with a strong international track record and now leads the ActiFS (Physical Activity, Fatigue, Health) academic chair.Prof. Millet was named at the Institut Universitaire de France as a Senior member in 2019 and director of the inter-university Laboratory of Human Movement Biology in 2020.His general research area investigates the physiological, neurophysiological and biomechanical factors associated with fatigue, both in extreme exercise and in patients (neuromuscular diseases, cancer, ICU). His research is focusing on understanding fatigue in order to create tailored rehabilitation programs for clinical populations in order to enhance patients' quality of life.In July 2021, he had published 5 books and 260 journal articles (cited > 10,700 times), his H index was 55. He has supervised 37 postdoctoral fellows and PhD students coming from 13 different countries and he served as an external reviewer for over 60 PhD candidates. Guillaume has been an invited speaker ~ 137 times in 17 different countries.Dr Millet's profile here: https://libm.univ-st-etienne.fr/en/research-teams/paf/researchers/millet-guillaume.html Research gate https://www.researchgate.net/profile/Guillaume-Millet-3 Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwillidenCurranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk ooff your first order
Join us as we talk to Ashish Jhina, the Co-founder Jumbotail about their story. In 2005, Ashish earned a dual degree in Biochemical Engineering and Biotechnology from IIT Delhi. He later pursued an MBA from the Stanford University Graduate School of Business and an MS in Environment and Resources—Freshwater from Stanford University in 2011. During his time at IIT Delhi, Ashish gained valuable experience interning at the Technical University of Denmark and the French National Institute of Agricultural Research. Subsequently, he worked with prominent companies such as Boston Consulting Group (BCG) and Moutain Hazelnuts. In 2009, he co-founded a company named NextDrop before co-founding Jumbotail in 2015. Ashish's dedication to excellence and his commitment to empowering retailers have resulted in Jumbotail being recognized as a transformative force within the industry. Apart from his contributions to Jumbotail, Ashish is highly regarded as a leading figure in the entrepreneurial community. For more visit - https://ajuniorvc.com/podcast/
Video: Scientist Carl Sagan testifying to the U.S. Senate in 1985 on the greenhouse effect: (2:00) WEF: The Most Evil Business in the World – Samuel Leeds (10:49) Israel caught hiding BOMBSHELL Pfizer Frequent nut consumption associated with less inflammation Brigham and Women's Hospital, September 1, 2022 In a study of more than 5,000 people, investigators from Brigham and Women's Hospital have found that greater intake of nuts was associated with lower levels of biomarkers of inflammation, a finding that may help explain the healthbenefits of nuts. The results of the study appear in the American Journal of Clinical Nutrition. “Population studies have consistently supported a protective role of nuts against cardiometabolic disorders such as cardiovascular disease and type 2 diabetes, and we know that inflammation is a key process in the development of these diseases,” said corresponding author Ying Bao, MD, ScD, an epidemiologist in BWH's Channing Division of Network Medicine. “Our new work suggests that nuts may exert their beneficial effects in part by reducing systemic inflammation.” Previously Bao and her colleagues observed an association between increased nut consumption and reduced risk of major chronic diseases and even death, but few prospective cohort studies had examined the link between nut intake and inflammation. In the current study, the research team performed a cross-sectional analysis of data from the Nurses' Health Study, which includes more than 120,000 female registered nurses, and from the Health Professionals Follow-Up Study, which includes more than 50,000 male health professionals. The team assessed diet using questionnaires and looked at the levels of certain telltale proteins known as biomarkers in blood samples collected from the study participants. They measured three well-established biomarkers of inflammation: C-reactive protein (CRP), interleukin 6 (IL6) and tumor necrosis factor receptor 2 (TNFR2). After adjusting for age, medical history, lifestyle and other variables, they found that participants who had consumed five or more servings of nuts per week had lower levels of CRP and IL6 than those who never or almost never ate nuts. In addition, people who substituted three servings per week of nuts in place of red meat, processed meat, eggs or refined grains had significantly lower levels of CRP and IL6. Peanuts and tree nuts contain a number of healthful components including magnesium, fiber, L-arginine, antioxidants and unsaturated fatty acids such as α-linolenic acid. Researchers have not yet determined which of these components, or if the combination of all of them, may offer protection against inflammation, but Bao and her colleagues are interested in exploring this further through clinical trials that would regulate and monitor diet. “Much remains unknown about how our diet influences inflammation and, in turn, our risk of disease,” said Bao. “But our study supports an overall healthful role for nuts in the diet and suggests reducing inflammation as a potential mechanism that may help explain the benefits of nuts on cardiometabolic diseases.” Blueberry extract could help fight gum disease and reduce antibiotic use Laval University (Quebec), September 2, 2022 Gum disease is a common condition among adults that occurs when bacteria form biofilms or plaques on teeth, and consequently the gums become inflamed. Some severe cases, called periodontitis, call for antibiotics. But now scientists have discovered that wild blueberry extract could help prevent dental plaque formation. Their report in ACS' Journal of Agricultural and Food Chemistry could lead to a new therapy for periodontitis and a reduced need for antibiotics. Many people have had some degree of gum inflammation, or gingivitis, caused by dental plaque. The gums get red and swollen, and they bleed easily. If left unchecked, the condition can progress to periodontitis. The plaque hardens into tartar, and the infection can spread below the gum line and destroy the tissue supporting the teeth. To treat this condition, dentists scrape off the tartar and sometimes have to resort to conventional antibiotics. But recently, researchers have started looking at natural antibacterial compounds to treat gum disease. Daniel Grenier and colleagues wanted to see if blueberry polyphenols, which work against foodborne pathogens, could also help fight Fusobacterium nucleatum, one of the main species of bacteria associated with periodontitis. In the lab, the researchers tested extracts from the wild lowbush blueberry, Vaccinium angustifolium Ait., against F. nucleatum. The polyphenol-rich extracts successfully inhibited the growth of F. nucleatum, as well as its ability to form biofilms. It also blocked a molecular pathway involved in inflammation, a key part of gum disease. The researchers say they're developing an oral device that could slowly release the extract after deep cleaning to help treat periodontitis. Meat consumption contributing to global obesity University of Adelaide, August 11, 2022 Should we be warning consumers about over-consumption of meat as well as sugar? That's the question being raised by a team of researchers from the University of Adelaide, who say meat in the modern diet offers surplus energy, and is contributing to the prevalence of global obesity. “Our findings are likely to be controversial because they suggest that meat contributes to obesity prevalence worldwide at the same extent as sugar,” says Professor Maciej Henneberg. “In the analysis of obesity prevalence across 170 countries, we have found that sugar availability in a nation explains 50% of obesity variation while meat availability another 50%. After correcting for differences in nations' wealth (Gross Domestic Product), calorie consumption, levels of urbanization and of physical inactivity, which are all major contributors to obesity, sugar availability remained an important factor, contributing independently 13%, while meat contributed another 13% to obesity. “While we believe it's important that the public should be alert to the over-consumption of sugar and some fats in their diets, based on our findings we believe meat protein in the human diet is also making a significant contribution to obesity,” Professor Henneberg says. “There is a dogma that fats and carbohydrates, especially fats, are the major factors contributing to obesity,” Mr You says. “Whether we like it or not, fats and carbohydrates in modern diets are supplying enough energy to meet our daily needs. Because meat protein is digested later than fats and carbohydrates, this makes the energy we receive from protein a surplus, which is then converted and stored as fat in the human body.” “Nevertheless, it is important that we show the contribution meat protein is making to obesity so that we can better understand what is happening. In the modern world in which we live, in order to curb obesity it may make sense for dietary guidelines to advise eating less meat, as well as eating less sugar,” he says. Study suggests possible link between artificial sweeteners and heart disease French National Institute for Health and Medical Research, September 7, 2022 A large study of French adults published by The BMJ today suggests a potential direct association between higher artificial sweetener consumption and increased cardiovascular disease risk, including heart attack and stroke. The findings indicate that these food additives, consumed daily by millions of people and present in thousands of foods and drinks, should not be considered a healthy and safe alternative to sugar, in line with the current position of several health agencies. Artificial sweeteners are widely used as no- or low-calorie alternatives to sugar. They represent a $7.2 billion (£5900m; €7000m) global market and are found in thousands of products worldwide, particularly ultra-processed foods such as artificially sweetened drinks, some snacks, and low calorie ready meals. Several studies have linked consumption of artificial sweeteners or artificially sweetened beverages (ASB) to weight gain, high blood pressure, and inflammation. To investigate this further, a team of researchers at the French National Institute for Health and Medical Research (Inserm) and colleagues drew on data for 103,388 participants (average age 42 years; 80% female) of the web-based NutriNet-Santé study, launched in France in 2009 to investigate relations between nutrition and health. Dietary intakes and consumption of artificial sweeteners were assessed by repeated 24-hour dietary records and a range of potentially influential health, lifestyle, and sociodemographic factors were taken into account. A total of 37% of participants consumed artificial sweeteners, with an average intake of 42.46 mg/day, which corresponds to approximately one individual packet of table top sweetener or 100 mL of diet soda. The researchers found that total artificial sweetener intake was associated with an increased risk of cardiovascular disease (absolute rate 346 per 100,000 person years in higher consumers and 314 per 100,000 person years in non-consumers). Artificial sweeteners were more particularly associated with cerebrovascular disease risk (absolute rates 195 and 150 per 100,000 person-years in higher and non-consumers, respectively). Aspartame intake was associated with increased risk of cerebrovascular events (186 and 151 per 100,000 person-years in higher and non-consumers, respectively), while acesulfame potassium and sucralose were associated with increased coronary heart disease risk (acesulfame potassium: 167 and 164 per 100,000 person-years; sucralose: 271 and 161 per 100,000 person-years in higher and non-consumers, respectively). Your soap and toothpaste could be messing with your microbiome University of Chicago, September 2, 2022 Antimicrobial chemicals found in common household products could be wreaking havoc with people's guts, according to a research paper out this week in the journal Science. Triclosan is an antibacterial compound used in soaps, detergent and toothpaste, as well as toys and plastics. It was originally only used in hospitals, but it found its way into homes as Americans became more germ-phobic. (However, recent studies have found it no more effective at killing bacteria than plain soap. ) Now, there are growing concerns about the possible negative effects of the chemical on human health and the environment. According to the US Food and Drug Administration (FDA), animal studies have shown that the chemical can act as a hormone disruptor. A 2008 study found traces of triclosan in the urine of 75% of the participants – some as young as six. The chemical has also been found in more than half of freshwater streams in the US. Disturbing the human microbiome has been “linked to a wide array of diseases and metabolic disorders, including obesity, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) and behavioral and metabolic disorders,” wrote the paper's authors, Alyson L Yee and Jack A Gilbert. Yee and Gilbert also suggested that exposure to triclosan could be even more detrimental to the health of developing fetuses and newborns than to adults. A 2014 New York University study found that gut disruptions in early infancy could have lasting negative effects on immune and brain development. Triclosan could also be contributing to antibiotic resistance, which scientists believe is caused by the overuse of antimicrobials in humans and animals. There are partial bans of the chemical in the European Union and in Minnesota, and the FDA says it will continue reviewing the chemical for its safety. Exposure to phthalates could be linked to pregnancy loss Peking University, September 2, 2022 A new study of more than 300 women suggests that exposure to certain phthalates — substances commonly used in food packaging, personal-care and other everyday products — could be associated with miscarriage, mostly between 5 and 13 weeks of pregnancy. The research, appearing in the ACS journal Environmental Science & Technology, is the first epidemiological study on non-work-related exposure to phthalates to provide evidence for the possible link among a general population. Out of concern over the potential health effects of phthalates, the U.S. has banned six of these substances from use in certain products made for young children. But many are still included as ingredients in paints, medical tubes, vinyl flooring, soaps, shampoos and other items. Research on phthalates has shown that long-term exposure to low levels of some of these compounds harms lab animals' health and can increase their risk for pregnancy loss. Additionally, at least one study found that female factory workers exposed to high levels of phthalates through their work were at a higher risk for miscarriage. But there is little epidemiological evidence of phthalates' effects on pregnancy among women with non-occupational exposure. Jianying Hu, Huan Shen and colleagues wanted to find out if there might be a link. The researchers tested urine samples from 132 women who had miscarriages and 172 healthy pregnant women in China. They found pregnancy loss was associated with higher levels of urinary phthalate metabolites from diethyl phthalate (DEP), di-isobutyl phthalate (DiBP) and di-n-butyl phthalate (DnBP). Although this doesn't prove that phthalates cause pregnancy loss, the study suggests an association exists that the researchers say should be studied further.
If you don't get quality sleep on a regular basis, you might have a higher risk for heart disease and stroke. In a new study presented at the European Society of Cardiology Congress 2022, researchers at the French National Institute of Health and Medical Research studied 7,200 adults, looking at five sleep habits and baseline […] The post 268. Sleeping better linked to lower risk of heart disease and stroke appeared first on Dr. David Geier - Feel and Perform Better Than Ever.
In this episode of Run with Fitpage, we had one of the top researchers globally, Dr. Guillaume Millet, to discuss a topic that is one of the most discussed and sought-after topics among us runners - FATIGUE. Dr. Guillaume Millet, Ph.D., is a professor at Jean Monnet University in Saint-Etienne. From 1998 to 2013, he held various academic positions in France, including a 4-year full-time research contract at the French National Institute for Medical Research (INSERM). He also was Vice-Chair of Research of the Canadian Society for Exercise Physiology from 2014 to 2016. His general research area investigates the physiological, neurophysiological, and biomechanical factors associated with fatigue, both during extreme exercise and in patients (neuromuscular diseases, cancer, ICU). His research is focusing on understanding fatigue in order to create tailored rehabilitation programs for clinical populations and enhance patients' quality of life. In July 2022, he had published over 275 journal articles. Guillaume has practiced various endurance sports in competition for 30 years. Among other results, he placed 3 times in the top 6 at the Ultra-Trail du Mont-Blanc®. He has published 5 books on physiology or training in endurance sports (one in English: “How to succeed at UTMB”). His book "Ultra-trail, Plaisir, performance et santé" has sold more than 12,000 copies.Follow Dr. Millet on Twitter - @kinesiologuiTo know more, log on to www.kinesiologui.comVikas hosts this weekly podcast and enjoys nerding over-exercise physiology, nutrition, and endurance sport in general. He aims to get people to get out and 'move'. When he is not working, he is found running, almost always. He can be found on nearly all social media channels but Instagram is preferred:)Reach out to Vikas:Instagram: @vikas_singhhLinkedIn: Vikas SinghGmail: vikas@fitpage.inTwitter: @vikashsingh1010
In this wide-ranging episode, we explored ideas in agriculture on how to make it both more productive and ecologically friendly. Our guest is Laurent Penet, PhD, a researcher with the French National Institute for Agriculture, Food and Environment. While we strayed from the initial question, we did cover a lot of ground on maintaining our ability to continue to produce food in the tropics and the temperate zones, how to encourage biodiversity by not killing all the weeds, why we need pollinators, and reiterated that farmers are great resources because they know the land they are working.
Mathilde Caron is a PhD. candidate at the French National Institute for Research in Digital Science and Technology and at Facebook AI (Meta AI). She does the majority of her research in the field of Machine learning called self-supervised learning. She has a few first authorships on important academic papers in the space. Her work: https://scholar.google.com/citations?user=eiB0s-kAAAAJ&hl=fr You can donate to this podcast at this bitcoin address: 33wejXuGGDtQj9GPwCgjwPxPq4dc4muZjg --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/idris-sunmola/support
Ruslan Sadykov is a researcher in the Bordeaux center of Inria, French National Institute for Informatics and Automatics. He received his master degree in Operations Research in Kazan State University, Russia, and his Ph.D. degree in Applied Mathematics in 2006 at CORE, Université Catholique de Louvain in Belgium. He was a postdoctoral researcher in Ecole Polytechnique in Paris before joining the ReAlOpt team at Inria Bordeaux as a research fellow in 2008. He was a visiting researcher at Universidade Federal Fluminense, Niteroi, Brazil during one year in 2015-2016. His research interests are in integer programming based decomposition approaches for solving combinatorial optimization problems with applications in vehicle routing, scheduling, cutting and packing. He is an author of many papers published in prestigious journals such as INFORMS Journal on Computing, European Journal of Operational Research, Computers and Operations Research, Journal on Scheduling, Mathematical Programming, Transportation Science, and Operations Research.
Lars Sandved-Smith – Meditation in Plain English with a Neuroscientist Lars stopped by to deliver the most practical podcast to date. Lars is a neuroscientist and PhD researcher at INSERM (The Institut national de la santé et de la recherche médicale) which is the French National Institute of Health and Medical Research. Lars walked us through the what, why and how of meditation in the most digestible format. He uncovered what happens to our neurology when we enter a meditative state. He showcased what benefits being metacognitive has on our everyday lives. He delivered his thoughts on meditation apps (such as Headspace) and most importantly he busts the mythical excuse of “meditation is just not for me” Stick around for a mid-podcast one rep max of meditation! Thanks Lars for stopping by on your boat (he literally recorded from his boat in Spain!!) - You can find THE FLOATING STUDIO and Lars' free classes: http://thefloatingstudio.com/ You can find meditation using HEADSPACE, CALM and INSIGHT TIMER apps.
Popular science and cell biology collide in this episode as Dodi and Conor discuss the science of cryogenics and its diverse applications. They are joined by Cytiva Senior Scientists and cryobiologists, Peter Kilbride and Julie Meneghel, as well as Fernanda Fonseca, Research Director at the French National Institute for Agriculture, Food, and Environment (INRAE). Executive Producer and PopSci enthusiast, Andrea Kilin, kicks off the discussion by sharing her experience with cryotherapy!
On the show today is Andrea Rivero, a PhD student at the French National Institute for Industrial Environment and Risks. We discuss her moving from Bolivia to France to Bolivia and back to France again and all the culture shock and challenges that entails. She talks about her time working at a large company and why she decided to go back to academia, and she tells us all about metallic nanoparticles and why they can cause so much trouble when they leak into freshwater ecosystems. "Cool Vibes" by Kevin MacLeod (incompetency.com) Licensed under Creative Commons: By Attribution 3.0 License
In the 17th and final episode of our series on science, policy, and pandemics, our host Dr Rob Doubleday and expert guests explore lessons learnt during the covid-19 pandemic and how researchers might use those lessons to prepare for future pandemics. CSaP's Science and Policy Podcast is a production of the Centre for Science and Policy at the University of Cambridge. This series on science, policy and pandemics is produced in partnership with Cambridge Infectious Diseases and the Cambridge Immunology Network. Our guests this week: Professor James Wood is Head of Department of Veterinary Medicine and Alborada Professor of Equine and Farm Animal Science. He is a veterinary epidemiologist who specializes in emerging and zoonotic infectious diseases, with a focus on bat transmitted viruses in sub-Saharan Africa and bovine tuberculosis. Professor Andres Floto is Professor of Respiratory Biology at the University of Cambridge, a Wellcome Trust Senior Investigator, and Research Director of the Cambridge Centre for Lung Infection at Papworth Hospital, Cambridge. Professor Sylvia Richardson is the Director of the MRC Biostatistics Unit and holds a Research Professorship in the University of Cambridge since 2012. She was previously Directeur de Recherches at the French National Institute for Medical Research INSERM, where she held research positions for 20 years. -- CSaP: The Science & Policy Podcast is hosted by CSaP Executive Director Dr Rob Doubleday, and is edited and produced by CSaP Communications Coordinator Kate McNeil. If you have feedback about this episode, or questions you would like us to address in a future week, please email enquiries@csap.cam.ac.uk.
Interview begins: 6:08Debrief begins: 37:58Today we are talking with Saurabh Sharma He is a partner at Jump Capital, a thesis led sector-focused and operating centric venture capital firm specializing in series A and B in growth-stage investments, Jump Capital invest in data-driven technology companies within the FinTech, B2B SaaS, IT data infrastructure and media sectors.Saurabh has a diverse background in investing, operations & product management and leads Jump's efforts in Enterprise Software and IT Infrastructure, his career as a High-Performance Computing researcher at French National Institute for Scientific Research where he focused on Compiler Optimization for mission-critical computing.Key points: Private equity style in India. (10:19) Working for Groupon (12:18) Limitations when it comes to data science (14:56) What makes Jump Capital different? (18:47) Learn more about Jump Capital: https://jumpcap.comFollow Saurabh Sharma on Linkedin: https://www.linkedin.com/in/saurabh-sharma-6ba69a1/---This episode of upside is also sponsored by Tresta. Tresta is a mobile app that lets you do business calling and texting from anywhere. With Tresta, you can set up your business phone number, download the app, and start calling and texting UNLIMITED right away.Tresta is the best business phone app on the market, whether you're a founder or freelancer / just starting your business, or you're already established. Growing your network and your business is all about communication. You've got to be available, no matter where you are. Tresta offers the call management features that empower you to communicate smarter and more efficiently, like auto attendants, call recording, user groups, and more. And you don't need any special equipment – just the smartphone you're already using. Tresta is easy to configure, so you can set everything up yourself – all online.It's just $15 per user per month, with no contract, so start your free 30-day trial today at https://tresta.com/upside–Want to share information about your company, or an opportunity with the upside audience?Book a classified advertisement and your advertisement will be read in an upcoming episode of the show.Classified ads are priced at $100, and are: Read by Jay and/or Eric on upside Linked from the show notes Linked from this website, upside.fm
Software Engineering Radio - The Podcast for Professional Software Developers
Jens Gustedt, author of the Modern C book, former co-editor of the C standard document ISO/IEC 9899:2018 and a senior scientist at the French National Institute for Computer Science and Control (INRIA) discuss what is classed as Modern C, what is legacy C and what has changed in the past 50 years in the C […]
The Languedoc Roussillon region produces good quality, reasonably-priced wine, but for how long? In June winegrowers were hard hit when temperatures reached 46 degrees Celsius, literally scorching the grapes on the vines. Extreme weather used to be the exception, now it's becoming the norm. We report from a village near Montpellier where winegrowers, on the frontline of climate change, are working with INRA to find ways to adapt and survive. Also, at least 11 million French people could be considered caregivers, taking care of elderly parents, disabled spouses, chronically-ill family members. Dr. Hélène Rossinot calls them the invisible backbone of the French healthcare system, and warns that the lack of recognition can lead to burn-out. She talks about what caregivers do, and what France should do for them. And the French love affair with burgers! McDonald's marks its 40th anniversary in the land of haute cuisine. But there's more to the official story. In this episode: - Robin Williamson, winemaker, Domaine de Saumarez - Joel Anthérieu, winemaker, Le Clos d'Isidore - Régis Sudre, winemaker, Domaine St Julia - Nathalie Ollat and Jean-Marc Touzard, of INRA, the French National Institute for Agricultural Research - Helene Rossinot, doctor, author of Aidants, ces invisibles (Those invisible caregivers) Subscribe to the Spotlight on France podcast on iTunes (link here) or Google podcasts (link here). For more stories about France and beyond, visit www.rfienglish.com.
Is there a European way to understand and manage intellectual property (IP)? Since the 18th century, Europe has always been at the forefront of innovation and competitiveness, as explained by Benoît Battistelli, who held various roles in French government departments and embassies before serving as Director General of the French National Institute for Industrial Property. and then President of the European Patent Office, one of the five largest IP offices in the world (7,000 staff), from 2010 to 2018. Currently, Mr. Battistelli is President of theAdministrative Board of the Center for International Intellectual Property Studies (CEIPI), Strasbourg, France. He shares his vision of the IP landscape and its challenges, particularly related to innovation and reforms to gain more efficiency.Every two weeks, on Tuesday, Brand & New gives the floor to inspiring individuals, with a 360-degree vision, to help brand owners, intellectual property lawyers, and marketing and finance professionals (and beyond!) stay curious and agile in an ever-evolving business environment. Brand & New is a production of the International Trademark AssociationHosted by Audrey DauvetContribution of M. Halle & S. Lagedamond - Music by JD BeatsFOR MORE INFORMATION, VISIT INTA.ORGTo go further:About Benoît Battistelli (link to http://www.ceipi.edu/en/news/piece-of-news/?tx_ttnews%5Btt_news%5D=10044&cHash=93b85ee7d4e8671ecb5bf44626b1f666)Also of interest:- European Patent Office (link to https://www.epo.org/index.html and https://worldwide.espacenet.com)- IP5 (link to https://www.fiveipoffices.org/)-INTA Daily News: How IP Offices Use Artificial Intelligence (link to https://www.inta.org/PDF%20Library/2019Daily/2019DailyNews_Day5.pdf)
In June, I will be traveling to Kyoto, Japan for the 5thWorld Parkinson Congress(WPC). WPC is a global Parkinson's event that opens its doors to all members of the Parkinson's community, from neurologists and researchers to those living with the disease. Since my diagnosis in August 2017, I’ve launched the podcast When Life Gives You Parkinson’s. As an extension of that podcast, I have teamed up with the World Parkinson Coalition to help preview WPC2019. Etienne Hirsch is Director of the French National Institute for Neuro Science, neurology and psychiatry. He’s a board member and chair for the basic science program committee for this year’s WPC. In his plenary talk, Hirsch will be examining the question, “Are we moving towards personalize medicine?” Hirsch isn’t hiding his passion for the topic, “I think that it is the most important challenge these days for Parkinson's disease.” He adds, “By the way I should not say Parkinson's disease, I should say Parkinson's diseaseswith an “s.” The concept is that everyone diagnosed with Parkinson’s is not dealing with the same disease, but different diseases that deserve different treatments. Much of Hirsch’s work revolves his belief that inflammation may actually trigger the events that lead to the death of the dopamine producing brain cells. He recalls that, until recently, it was a controversial theory, “Some people were even laughing saying that neuro inflammation is a consequence of neuron degeneration. And now we know that in fact the neuro inflammatory processes are not just a consequence of neuron degeneration. These events really participate to the cascade of events leading to degeneration in the past.” In his workshop, Hirsch will help lead a discussion around why some cells degenerate in people with Parkinson’s and some do not. Eli Pollard, Executive Director of the World Parkinson Coalition, which is the organization that hosts the triennial World Parkinson Congress is expecting just over 3,000 people to attend the event in Kyoto. She encourages participants to check out “Wellness Way” which features free fitness and exercises classes in the renewal room, complimentary massage and Raiki, the Care Partner Lounge, there is a Quiet Room for people who might need to escape the crowds or take a quick nap. There’s also a clinical research village sponsored by the Michael J. Fox Foundation and with in-kind support from the Cure Parkinson's Trust. “It is a space for just people to learn about clinical research clinical trials what you should ask if you want to engage in a clinical trial.” Pollard continues, “What are your rights as a participant in a clinical trial? What do you need to know before you sign on the dotted line?” The research village will be open all the hours that the exhibit halls. Finally, Pollard has some last minute packing tips. She recommends you pack comfortable clothes and a rain coat, because it’s going to be hot and it is the rainy season in Kyoto. While some attendees will be wearing shorts, there will be air conditioning in the conference center, so pants may be more appropriate if you tend to be cold. Do not forget to bring a pen and pad of paper to take notes and trade information with other attendees, unless you are using your phone or tablet. Most importantly, if you are a person with Parkinson’s, Pollard urges you to pack at least twice the amount of medication you think you will need and better yet, pack three times the amount. She recommends you spread it out between your carry on, your checked luggage and your travel companion. Each episode of the WPC2019 Podcast, I check in with James Heron, the Executive Director of the Japanese-Canadian Cultural Centre. This week, we wrap up our Japanese tutorial with a hodge-podge of tips and insights. Key among them is to speak directly and clearly. In North America, we tend to use idioms like “pulling-your-leg,” “bite-the-bullet,” and “dime a dozen.” When literally translated by a Japanese speaker, these phrases can be confusing. Heron uses “pulling-your-leg” as an example, “There is an expression in Japanese, ashi o hipparu,which means you have to pull someone's leg which actually means to purposefully hold someone back, to make them fail, almost to sabotage someone.” Follow me, Larry Gifford Twitter: @ParkinsonsPod Facebook: Facebook.com/ParkinsonsPod Instagram: @parkinsonspod For more info on the World Parkinson Congress head to www.WPC2019.org Facebook: Facebook.com/WorldPDCongress/ Twitter: @WorldPDCongress YouTube: WorldPDcongress Instagram: @worldpdcongress Thank you to: Etienne Hirsch, Director French National Institutes of neurosciences, cognitive sciences, neurology and psychiatry. Eli Pollard, Executive Director World Parkinson Coalition James Heron, Executive Director of Japanese Canadian Cultural Centre Credits Dila Velazquez – Story Producer Rob Johnston – Senior Audio Producer
Professor Véronique Bénéï from the French National Institute for Scientific Research talks with Eline Kieft about using her body as a source of knowledge in research, teaching and learning.
Dr. Nicolas Rougier is a full-time research scientist at the French National Institute for Research in Computer Science and Control. During the past decades he’s been working extensively on visual attention in order to understand how we visually explore a scene. Dr. Rougier discusses his work and visual attention and computation neuroscience in particular. He also dives deeper into how seeing is mostly an illusion and that we do not process all visual information that passed through our eyes and we're making deliberate (consciously or not) choices on what we concentrate.
INRA is the French National Institute for Agricultural Research. We speak with Bernard Segway on the potential effects of climate change on grape growing.