Podcasts about wake forest institute

Phase Holographic Imaging (OTCQB: PHIXF) is a medical technology company that develops and markets its non-invasive time-lapse imaging instruments for long-term quantitative analysis of living cells. Patrik Eschricht, CEO of PHI, joins us to discuss how they distinguish themselves from competitors by working with Wake Forest Institute of Regenerative Medicine, as well as how they have taken action on future plans. View Podcast Transcript

Subscriber-only episode3D printed skin – huge advances could revolutionise wound healingTwo major advances in 3D printing human skin could lead to major advances in wound healing.  A team of scientists at Wake Forest Institute for Regenerative Medicine in the US have printed full thickness human skin for the first time. They successfully printed all six major human cell types present in human skin, creating normal skin layers -  the epidermis, dermis, and hypodermis. The bioprinted skin formed blood vessels, skin patterns, and showed normal tissue formation. It also produced more collagen which will reduce scarring. If you pay to subscribe to the extended version of the podcast you can hear about another study where the Brazilian cosmetic company Grupo Boticário  has 3D printed skin which includes hair follicles. Stolen mobile phones in Brazil can now be blocked immediatelyA new system that blocks stolen mobile phones via an app or the web has been launched in Brazil. Almost a million mobiles were stolen in 2022 in Brazil. Many Brazilians use the instant payment system Pix,  so blocking a stolen phone as quickly as possible can significantly reduce the amount money stolen from someone's account. More than a million people have registered to use the Celular Seguro programme in its first two weeks. Using the country's citizen registration scheme, it allows people to block or unblock their phones from a trusted and registered source. The programme is presented by Gareth Mitchell and the studio expert is Angelica Mari.More on this week's stories: Multicellular bioprinted skin facilitates human-like skin architecture in vivo Incorporation of hair follicles in 3D bioprinted models of human skinBrazil's Grupo Boticário develops 3D skin with bioprinting technologySafe Cell Phone is now available on GOV.BRStolen cell phone blocking will be immediate via application or web by registered personEditor: Ania LichtarowiczProduction Manager: Liz Tuohy Recording and audio editing : Lansons | Team Farner For new episodes, subscribe wherever you get your podcasts.Follow us on all the socials: Join our Facebook group Instagram Twitter/X If you like Somewhere on Earth, please rate and review it on Apple PodcastsContact us by email: hello@somewhereonearth.coSend us a voice note: via WhatsApp: +44 7486 329 484Find a Story + Make it News = Change the World

3D printed skin – huge advances could revolutionise wound healingTwo major advances in 3D printing human skin could lead to major advances in wound healing.  A team of scientists at Wake Forest Institute for Regenerative Medicine in the US have printed full thickness human skin for the first time. They successfully printed all six major human cell types present in human skin, creating normal skin layers -  the epidermis, dermis, and hypodermis. The bioprinted skin formed blood vessels, skin patterns, and showed normal tissue formation. It also produced more collagen which will reduce scarring. If you pay to subscribe to the extended version of the podcast you can hear about another study where the Brazilian cosmetic company Grupo Boticário  has 3D printed skin which includes hair follicles. Stolen mobile phones in Brazil can now be blocked immediately A new system that blocks stolen mobile phones via an app or the web has been launched in Brazil. Almost a million mobiles were stolen in 2022 in Brazil. Many Brazilians use the instant payment system Pix,  so blocking a stolen phone as quickly as possible can significantly reduce the amount money stolen from someone's account. More than a million people have registered to use the Celular Seguro programme in its first two weeks. Using the country's citizen registration scheme, it allows people to block or unblock their phones from a trusted and registered source.  The programme is presented by Gareth Mitchell and the studio expert is Angelica Mari. More on this week's stories: Multicellular bioprinted skin facilitates human-like skin architecture in vivo Incorporation of hair follicles in 3D bioprinted models of human skinBrazil's Grupo Boticário develops 3D skin with bioprinting technologySafe Cell Phone is now available on GOV.BRStolen cell phone blocking will be immediate via application or web by registered personSupport the showEditor: Ania LichtarowiczProduction Manager: Liz Tuohy Recording and audio editing : Lansons | Team Farner For new episodes, subscribe wherever you get your podcasts.Follow us on all the socials: Join our Facebook group Instagram Twitter/X If you like Somewhere on Earth, please rate and review it on Apple PodcastsContact us by email: hello@somewhereonearth.coSend us a voice note: via WhatsApp: +44 7486 329 484Find a Story + Make it News = Change the World

One of the hardest parts of telling any history, is which innovations are significant enough to warrant mention. Too much, and the history is so vast that it can't be told. Too few, and it's incomplete. Arguably, no history is ever complete. Yet there's a critical path of innovation to get where we are today, and hundreds of smaller innovations that get missed along the way, or are out of scope for this exact story. Children have probably been placing sand into buckets to make sandcastles since the beginning of time. Bricks have survived from round 7500BC in modern-day Turkey where humans made molds to allow clay to dry and bake in the sun until it formed bricks. Bricks that could be stacked. And it wasn't long before molds were used for more. Now we can just print a mold on a 3d printer.   A mold is simply a block with a hollow cavity that allows putting some material in there. People then allow it to set and pull out a shape. Humanity has known how to do this for more than 6,000 years, initially with lost wax casting with statues surviving from the Indus Valley Civilization, stretching between parts of modern day Pakistan and India. That evolved to allow casting in gold and silver and copper and then flourished in the Bronze Age when stone molds were used to cast axes around 3,000 BCE. The Egyptians used plaster to cast molds of the heads of rulers. So molds and then casting were known throughout the time of the earliest written works and so the beginning of civilization. The next few thousand years saw humanity learn to pack more into those molds, to replace objects from nature with those we made synthetically, and ultimately molding and casting did its part on the path to industrialization. As we came out of the industrial revolution, the impact of all these technologies gave us more and more options both in terms of free time as humans to think as well as new modes of thinking. And so in 1868 John Wesley Hyatt invented injection molding, patenting the machine in 1872. And we were able to mass produce not just with metal and glass and clay but with synthetics. And more options came but that whole idea of a mold to avoid manual carving and be able to produce replicas stretched back far into the history of humanity. So here we are on the precipice of yet another world-changing technology becoming ubiquitous. And yet not. 3d printing still feels like a hobbyists journey rather than a mature technology like we see in science fiction shows like Star Trek with their replicators or printing a gun in the Netflix show Lost In Space. In fact the initial idea of 3d printing came from a story called Things Pass By written all the way back in 1945! I have a love-hate relationship with 3D printing. Some jobs just work out great. Others feel very much like personal computers in the hobbyist era - just hacking away until things work. It's usually my fault when things go awry. Just as it was when I wanted to print things out on the dot matrix printer on the Apple II. Maybe I fed the paper crooked or didn't check that there was ink first or sent the print job using the wrong driver. One of the many things that could go wrong.  But those fast prints don't match with the reality of leveling and cleaning nozzles and waiting for them to heat up and pulling filament out of weird places (how did it get there, exactly)! Or printing 10 add-ons for a printer to make it work the way it probably should have out of the box.  Another area where 3d printing is similar to the early days of the personal computer revolution is that there are a few different types of technology in use today. These include color-jet printing (CJP), direct metal printing (DMP), fused deposition modeling (FDM), Laser Additive Manufacturing (LAM, multi-jet printing (MJP), stereolithography (SLA), selective laser melting (SLM), and selective laser sintering (SLS). Each could be better for a given type of print job to be done. Some forms have flourished while others are either their infancy or have been abandoned like extinct languages. Language isolates are languages that don't fit into other families. Many are the last in a branch of a larger language family tree. Others come out of geographically isolated groups. Technology also has isolates. Konrad Zuse built computers in pre-World War II Germany and after that aren't considered to influence other computers. In other words, every technology seems to have a couple of false starts. Hideo Kodama filed the first patent to 3d print in 1980 - but his method of using UV lights to harden material doesn't get commercialized.  Another type of 3d printing includes printers that were inkjets that shot metal alloys onto surfaces. Inkjet printing was invented by Ichiro Endo at Canon in the 1950s, supposedly when he left a hot iron on a pen and ink bubbled out. Thus the “Bubble jet” printer. And Jon Vaught at HP was working on the same idea at about the same time. These were patented and used to print images from computers over the coming decades. Johannes Gottwald patented a printer like this in 1971. Experiments continued through the 1970s when companies like Exxon were trying to improve various prototyping processes. Some of their engineers joined an inventor Robert Howard in the early 1980s to found a company called Howtek and they produced the Pixelmaster, using hot-melt inks to increment the ink jet with solid inks, which then went on to be used by Sanders Prototype, which evolved into a company called Solidscape to market the Modelmaker. And some have been used to print solar cells, living cells, tissue, and even edible birthday cakes. That same technique is available with a number of different solutions but isn't the most widely marketable amongst the types of 3D printers available. SLA There's often a root from which most technology of the day is derived. Charles, or Chuck, Hull coined the term stereolithography, where he could lay down small layers of an object and then cure the object with UV light, much as the dentists do with fillings today. This is made possibly by photopolymers, or plastics that are easily cured by an ultraviolet light. He then invented the stereolithography apparatus, or SLA for short, a machine that printed from the bottom to the top by focusing a laser on photopolymer while in a liquid form to cure the plastic into place. He worked on it in 1983, filed the patent in 1984, and was granted the patent in 1986.  Hull also developed a file format for 3D printing called STL. STL files describe the surface of a three-dimensional object, geometrically using Cartesian coordinates. Describing coordinates and vectors means we can make objects bigger or smaller when we're ready to print them. 3D printers print using layers, or slices. Those can change based on the filament on the head of a modern printer, the size of the liquid being cured, and even the heat of a nozzle. So the STL file gets put into a slicer that then converts the coordinates on the outside to the polygons that are cured. These are polygons in layers, so they may appear striated rather than perfectly curved according to the size of the layers. However, more layers take more time and energy. Such is the evolution of 3D printing. Hull then founded a company called 3D Systems in Valencia California to take his innovation to market. They sold their first printer, the SLA-1 in 1988. New technologies start out big and expensive. And that was the case with 3D Systems. They initially sold to large engineering companies but when solid-state lasers came along in 1996 they were able to provide better systems for cheaper.  Languages also have other branches. Another branch in 3d printing came in 1987, just before the first SLA-1 was sold.  Carl Deckard  and his academic adviser Joe Beaman at the University of Texas worked on a DARPA grant to experiment with creating physical objects with lasers. They formed a company to take their solution to market called DTM and filed a patent for what they called selective laser sintering. This compacts and hardens a material with a heat source without having to liquify it. So a laser, guided by a computer, can move around a material and harden areas to produce a 3D model. Now in addition to SLA we had a second option, with the release of the Sinterstation 2500plus. Then 3D Systems then acquired DTM for $45 million in 2001. FDM After Hull published his findings for SLA and created the STL format, other standards we use today emerged. FDM is short for Fused Deposition Modeling and was created by Scott Crump in 1989. He then started a company with his wife Lisa to take the product to market, taking the company public in 1994. Crump's first patent expired in 2009.  In addition to FDM, there are other formats and techniques. AeroMat made the first 3D printer that could produce metal in 1997. These use a laser additive manufacturing process, where lasers fuse powdered titanium alloys. Some go the opposite direction and create out of bacteria or tissue. That began in 1999, when Wake Forest Institute of Regenerative medicine grew a 3D printed urinary bladder in a lab to be used as a transplant. We now call this bioprinting and can take tissue and lasers to rebuild damaged organs or even create a new organ. Organs are still in their infancy with success trials on smaller animals like rabbits. Another aspect is printing dinner using cell fibers from cows or other animals. There are a number of types of materials used in 3D printing. Most printers today use a continuous feed of one of these filaments, or small coiled fibers of thermoplastics that melt instead of burn when they're heated up. The most common in use today is PLA, or polylactic acid, is a plastic initially created by Wall Carothers of DuPont, the same person that brought us nylon, neoprene, and other plastic derivatives. It typically melts between 200 and 260 degrees Celsius. Printers can also take ABS filament, which is short for acrylonitrile-butadien-styerene. Other filament types include HIPS, PET, CPE, PVA, and their derivative forms.  Filament is fed into a heated extruder assembly that melts the plastic. Once melted, filament extrudes into place through a nozzle as a motor sends the nozzle on a x and y axis per layer.  Once a layer of plastic is finished being delivered to the areas required to make up the desired slice, the motor moves the extruder assembly up or down on a z axis between layers. Filament is just between 1.75 millimeters and 3 millimeters and comes in spools between half a kilogram and two kilograms. These thermoplastics cool very quickly. Once all of the slices are squirted into place, the print is removed from the bed and the nozzle cools off. Filament comes in a number of colors and styles. For example, wood fibers can be added to filament to get a wood-grained finish. Metal can be added to make prints appear metallic and be part metal.  Printing isn't foolproof, though. Filament often gets jammed or the spool gets stuck, usually when something goes wrong. Filament also needs to be stored in a temperature and moisture controlled location or it can cause jobs to fail. Sometimes the software used to slice the .stl file has an incorrect setting, like the wrong size of filament. But in general, 3D printing using the FDM format is pretty straight forward these days. Yet this is technology that should have moved faster in terms of adoption. The past 10 years have seen more progress than the previous ten though. Primarily due to the maker community. Enter the Makers The FDM patent expired in 2009. In 2005, a few years before the FDM patent expired, Dr. Adrian Bowyer started a project to bring inexpensive 3D printers to labs and homes around the world. That project evolved into what we now call the Replicating Rapid Prototyper, or RepRap for short.  RepRap evolved into an open source concept to create self-replicating 3D printers and by 2008, the Darwin printer was the first printer to use RepRap. As a community started to form, more collaborators designed more parts. Some were custom parts to improve the performance of the printer, or replicate the printer to become other printers. Others held the computing mechanisms in place. Some even wrote code to make the printer able to boot off a MicroSD card and then added a network interface so files could be uploaded to the printer wirelessly. There was a rising tide of printers. People were reading about what 3D printers were doing and wanted to get involved. There was also a movement in the maker space, so people wanted to make things themselves. There was a craft to it. Part of that was wanting to share. Whether that was at a maker space or share ideas and plans and code online. Like the RepRap team had done.  One of those maker spaces was NYC Resistor, founded in 2007. Bre Pettis, Adam Mayer, and Zach Smith from there took some of the work from the RepRap project and had ideas for a few new projects they'd like to start. The first was a site that Zach Smith created called Thingiverse. Bre Pettis joined in and they allowed users to upload .stl files and trade them. It's now the largest site for trading hundreds of thousands of designs to print about anything imaginable. Well, everything except guns. Then comes 2009. The patent for FDM expires and a number of companies respond by launching printers and services. Almost overnight the price for a 3D printer fell from $10,000 to $1,000 and continued to drop. Shapeways had created a company the year before to take files and print them for people. Pettis, Mayer, and Smith from NYC Resistor also founded a company called MakerBot Industries. They'd already made a little bit of a name for themselves with the Thingiverse site. They knew the mind of a maker. And so they decided to make a kit to sell to people that wanted to build their own printers. They sold 3,500 kits in the first couple of years. They had a good brand and knew the people who bought these kinds of devices. So they took venture funding to grow the company. So they raised $10M in funding in 2011 in a round led by the Foundry Group, along with Bezos, RRE, 500 Startups and a few others. They hired and grew fast. Smith left in 2012 and they were getting closer and closer with Stratasys, who if we remember were the original creators of FDM. So Stratasys ended up buying out the company in 2013 for $403M. Sales were disappointing so there was a changeup in leadership, with Pettis leaving and they've become much more about additive manufacturing than a company built to appeal to makers. And yet the opportunity to own that market is still there. This was also an era of Kickstarter campaigns. Plenty of 3D printing companies launched through kickstarter including some to take PLA (a biodegradable filament) and ABS materials to the next level. The ExtrusionBot, the MagicBox, the ProtoPlant, the Protopasta, Mixture, Plybot, Robo3D, Mantis, and so many more.  Meanwhile, 3D printing was in the news. 2011 saw the University of Southhampton design a 3d printed aircraft. Ecologic printing cars, and practically every other car company following suit that they were fabricating prototypes with 3d printers, even full cars that ran. Some on their own, some accidentally when parts are published in .stl files online violating various patents.  Ultimaker was another RepRap company that came out of the early Darwin reviews. Martijn Elserman, Erik de Bruin, and Siert Wijnia who couldn't get the Darwin to work so they designed a new printer and took it to market. After a few iterations, they came up with the Ultimaker 2 and have since been growing and releasing new printers  A few years later, a team of Chinese makers, Jack Chen, Huilin Liu, Jingke Tang, Danjun Ao, and Dr. Shengui Chen took the RepRap designs and started a company to manufacturing (Do It Yourself) kits called Creality. They have maintained the open source manifesto of 3D printing that they inherited from RepRap and developed version after version, even raising over $33M to develop the Ender6 on Kickstarter in 2018, then building a new factory and now have the capacity to ship well over half a million printers a year. The future of 3D Printing We can now buy 3D printing pens, over 170 3D Printer manufacturers including 3D systems, Stratasys, and Ceality but also down-market solutions like Fusion3, Formlabs, Desktop Metal, Prusa, and Voxel8. There's also a RecycleBot concept and additional patents expiring every year.  There is little doubt that at some point, instead of driving to Home Depot to get screws or basic parts, we'll print them. Need a new auger for the snow blower? Just print it. Cover on the weed eater break?  Print it. Need a dracolich mini for the next Dungeons and Dragons game? Print it. Need a new pinky toe. OK, maybe that's a bit far. Or is it? In 2015, Swedish Cellink releases bio-ink made from seaweed and algae, which could be used to print cartilage and later released the INKREDIBLE 3D printer for bio printing. The market in 2020 was valued at $13.78 billion with 2.1 million printers shipped. That's expected to grow at a compound annual growth rate of 21% for the next few years. But a lot of that is healthcare, automotive, aerospace, and prototyping still. Apple made the personal computer simple and elegant. But no Apple has emerged for 3D printing. Instead it still feels like the Apple II era, where there are 3D printers in a lot of schools and many offer classes on generating files and printing.  3D printers are certainly great for prototypers and additive manufacturing. They're great for hobbyists, which we call makers these days. But there will be a time when there is a printer in most homes, the way we have electricity, televisions, phones, and other critical technologies. But there are a few things that have to happen first, to make the printers easier to use. These include: Every printer needs to automatically level. This is one of the biggest reasons jobs fail and new users become frustrated. More consistent filament. Spools are still all just a little bit different. Printers need sensors in the extruder that detect if a job should be paused because the filament is jammed, humid, or caught. This adds the ability to potentially resume print jobs and waste less filament and time. Automated slicing in the printer microcode that senses the filament and slices. Better system boards (e.g. there's a tool called Klipper that moves the math from the system board on a Creality Ender 3 to a Raspberry Pi). Cameras on the printer should watch jobs and use TinyML to determine if they are going to fail as early as possible to halt printing so it can start over. Most of the consumer solutions don't have great support. Maybe users are limited to calling a place in a foreign country where support hours don't make sense for them or maybe the products are just too much of a hacker/maker/hobbyist solution. There needs to be an option for color printing. This could be a really expensive sprayer or ink like inkjet printers use at first We love to paint minis we make for Dungeons and Dragons but could get amazingly accurate resolutions to create amazing things with automated coloring.  For a real game changer, the RecycleBot concept needs to be merged with the printer. Imagine if we dropped our plastics into a recycling bin that 3D printers of the world used to create filament. This would help reduce the amount of plastics used in the world in general. And when combined with less moving around of cheap plastic goods that could be printed at home, this also means less energy consumed by transporting goods. The 3D printing technology is still a generation or two away from getting truly mass-marketed. Most hobbyists don't necessarily think of building an elegant, easy-to-use solution because they are so experienced it's hard to understand what the barriers of entry are for any old person. But the company who finally manages to crack that nut might just be the next Apple, Microsoft, or Google of the world.

Supply chains need to be transformed, not just optimized, to survive the climate crisis. In this episode, Deborah explores the “weird science” behind cutting-edge concepts with Tom Van Aken, CEO of Avantium, a plant-based plastics manufacturer, Dr. Anthony Atala, Director of the Wake Forest Institute of Regenerative Medicine and a bioengineering pioneer, Eben Bayer, CEO of Ecovative, a company that grows mushrooms as an alternative materials source, Tyler Cole, an electrofuels expert and the host of the Net-Zero Carbon podcast, and Zero100 research science director Colin Gilbert. Could the innovations we're exploring today completely change how supply chains source materials, manufacture goods, and ship products?Episode links:SynBio Radically Reinvents Supply Chain Avantium Tom Van Aken Avantium Holds First Piling Ceremony for its FDCA Flagship Plant Wake Forest Institute for Regenerative Medicine Dr. Anthony Atala Growing new organs Ecovative Eben Bayer Premium Leather Producer ECCO Leather Partners With Ecovative to Pursue New Mycelium Materials Net-Zero Carbon podcast Tyler Cole Freight Waves: The Nerve Center of the Global Supply Chain Developing Sustainable Aviation Fuel (SAF) The Paris Agreement Ambition gap

The Wake Forest Institute for Regenerative Medicine (WFIRM) is recognized as an international leader in translating scientific discovery into clinical therapies. Leading WFIRM is Dr. Tony Atala, whose research, innovation, and thought leadership have shaped the field of regenerative medicine for over two decades.Physicians and scientists at WFIRM were the first in the world to engineer laboratory-grown organs that were successfully implanted into humans. Today, this interdisciplinary team that numbers about 400 is working to engineer more than 40 different replacement tissues and organs, and to develop healing cell therapies – all with the goal to cure, rather than merely treat, disease. Dr. Atala joins Thomas Osha, the host of The Commons, for a conversation highlighting the science, progress, and promise of regenerative medicine.  To learn more about WFIRM, please visit: https://school.wakehealth.edu/Research/Institutes-and-Centers/Wake-Forest-Institute-for-Regenerative-Medicine.This is the first in a series of conversations with leading researchers around North America, exploring the breadth of research being conducted at leading Knowledge Communities.

Dr. Anthony Atala, MD, (https://school.wakehealth.edu/Faculty/A/Anthony-Atala) is the G. Link Professor and Director of the Wake Forest Institute for Regenerative Medicine, and the W. Boyce Professor and Chair of Urology. A practicing surgeon and a researcher in the area of regenerative medicine, fifteen applications of technologies developed Dr. Atala's laboratory have been used clinically. He is Editor of 25 books and 3 journals, has published over 800 journal articles, and has received over 250 national and international patents. Dr. Atala was elected to the Institute of Medicine of the National Academies of Sciences, to the National Academy of Inventors as a Charter Fellow, and to the American Institute for Medical and Biological Engineering. Dr. Atala is a recipient of the US Congress funded Christopher Columbus Foundation Award, bestowed on a living American who is currently working on a discovery that will significantly affect society; the World Technology Award in Health and Medicine, for achieving significant and lasting progress; the Edison Science/Medical Award for innovation, the R&D Innovator of the Year Award, and the Smithsonian Ingenuity Award for Bioprinting Tissue and Organs. Dr. Atala's work was listed twice as Time Magazine's Top 10 medical breakthroughs of the year, and once as one of 5 discoveries that will change the future of organ transplants. He was named by Scientific American as one of the world's most influential people in biotechnology, by U.S. News & World Report as one of 14 Pioneers of Medical Progress in the 21st Century, by Life Sciences Intellectual Property Review as one of the top key influencers in the life sciences intellectual property arena, and by Nature Biotechnology as one of the top 10 translational researchers in the world. Dr. Atala has led or served several national professional and government committees, including the National Institutes of Health working group on Cells and Developmental Biology, the National Institutes of Health Bioengineering Consortium, and the National Cancer Institute's Advisory Board. He is a founding member of the Tissue Engineering Society, Regenerative Medicine Foundation, Regenerative Medicine Manufacturing Innovation Consortium, Regenerative Medicine Development Organization, and Regenerative Medicine Manufacturing Society.

“The clinical finding showing that the cell therapy treatment safely reduced severe autism spectrum disorder characterizations in children is encouraging,” said Anthony Atala, M.D., Editor-in-Chief of STEM CELLS Translational Medicine and director of the Wake Forest Institute for Regenerative Medicine. “The findings are promising and open the opportunity for the development of a translational medicine approach that could help affected children.”

Brandon Scott Barney is the co-founder of Primary Ocean, a company that cultivates giant kelp, and Julie Allickson, the Chief Manufacturing Development Center Officer at Wake Forest Institute for Regenerative Medicine whose team is helping critically ill people by creating viable organs for transplants in a laboratory. Tune in to hear how these compassionate leaders found their callings and are now developing cutting-edge innovations that help people and the planet.

An estimated 107,000 people in the United States are currently on the waiting list for organ transplantation. These patients face waiting times of 3-5 years or longer before receiving an organ. Even after receiving a donated organ, organ-transplant patients face a high risk of tissue rejection. Regenerative medicine promises the possibility of laboratory-grown organs, specially tailored to the biology and needs of individual patients, but how close is this technology to reality? In this month's episode, we discuss the potential of regenerative medicine to replace damaged organs and tissues and cases where stem cell and regenerative medicine influence health today. Tiffany Garbutt from The Scientist's Creative Services team spoke with Anthony Atala, the W. Boyce Professor and Chair of Urology and the G. Link Professor and Director of the Wake Forest Institute for Regenerative Medicine to learn more. The Scientist Speaks is a podcast produced by The Scientist's Creative Services team. Our podcast is by scientists and for scientists. Once a month, we bring you the stories behind news-worthy molecular biology research. This month's episode is sponsored by PHCbi. PHC Corporation of North America is a global leader in the development, design, and manufacturing of laboratory equipment. Products include the space-saving and energy-efficient VIP® ECO, TwinGuard® and VIP Series ultra-low temperature freezers, cryogenic and biomedical freezers, pharmacy and high-performance refrigerators, cell culture CO2 and multigas incubators, and Drosophila and plant Growth Chambers.

Dr. Anthony Atala is the Founding Director of the Wake Forest Institute for Regenerative Medicine and the Chair of Urology at the Wake Forest School of Medicine. His team developed the first lab-grown organ to be implanted into a human and he currently oversees a team of over 400 researchers who are working to develop cell therapies and engineer replacement organs and tissues.

Dr. Ross, PhD, BCPP is a Biophysicist in the field of energy medicine working with the Wake Forest Institute of Regenerative Medicine. She is also the author of "Etiology: How to Detect Disease Before It Manifests In Your Body" She understands how energy affects biology and puts it into practice!  She has studied how energy affects cells and molecules in our body that modulate pain and inflammation.   Dr. Ross has so much to say in this podcast episode about increasing our vibrational energy to heal from illness. She also discusses her basic science research into the field of energy medicine, which I'm so excited about!! Hope you enjoy this episode! She's a treasure! SHOWNOTES HERE ---------------------------------------------------------------- Our Manifestation 4-Step Hypnosis Recordings is Still Available on Our Website for a Limited Time You can sign up here! ------------------------------------------------------------------ Don't forget to check out our social media, FOLLOW and leave us a comment! 1. Instagram @Health_Is_PowHer 2. Facebook  3. Pinterest ------------------------------------------------------------------ We hope you enjoy the episode and if you do, please SUBSCRIBE, RATE, and REVIEW So you can help us increase our reach to help more women awaken their best selves, have more energy, and live the life they dreamed of while healing and recovering from any pain and health issues! ----------------------------------------------------------------- The Health Is PowHer wellness coaching members club has launched! We'd love to have you and if you're interested in awakening your best self, having more energy, and living the life to your full health potential, and are determined to feel better then check us out with the link below! https://healthispowher.com/health-is-powher-members-club/ ------------------------------------------------------------------ DISCLAIMER   Anna Esparham, M.D.is a medical doctor, but she is not your doctor, and she is not offering medical advice on this podcast. If you are in need of professional advice or medical care, you must seek out the services of your own doctor or health care professional. The opinions of podcast guests are not necessarily those of Dr. Esparham, MD and Health Is PowHer, LLC and do not represent her or the company.  This podcast provides information only, and does not provide any financial, legal, medical or psychological services or advice. None of the content on this podcast prevents, cures or treats any mental or medical condition. You are responsible for your own physical, mental and emotional well-being, decisions, choices, actions and results. Health Is PowHer, LLC disclaims any liability for your reliance on any opinions or advice contained in this podcast.

Anthony Atala, MD (the G. Link Professor and Director of the Wake Forest Institute for Regenerative Medicine, and the W. Boyce Professor and Chair of Urology), joins host Lauren Richardson (@lr_bio) to discuss the results and implications of the article "A tissue-engineered uterus supports live births in rabbits" by Renata S. Magalhaes, J. Koudy Williams, Kyung W. Yoo, James J. Yoo & Anthony Atala, published in Nature Biotechnology.In the introduction, we also discuss the new article "Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis" by Alejandro Aguilera-Castrejon, Bernardo Oldak, Tom Shani, Nadir Ghanem, Chen Itzkovich, Sharon Slomovich, Shadi Tarazi, Jonathan Bayerl, Valeriya Chugaeva, Muneef Ayyash, Shahd Ashouokhi, Daoud Sheban, Nir Livnat, Lior Lasman, Sergey Viukov, Mirie Zerbib, Yoseph Addadi, Yoach Rais, Saifeng Cheng, Yonatan Stelzer, Hadas Keren-Shaul, Raanan Shlomo, Rada Massarwa, Noa Novershtern, Itay Maza & Jacob H. Hanna, published in Nature.

About Our Guest: Dr. Batra obtained his PhD in medical physiology from the University of Ottawa, Canada and completed post-doctoral training with world-renowned scientists in Sapporo, Japan and Berne, Switzerland. He is a Fellow of the American College of Cardiology and an Adjunct Professor at the Wake Forest Institute for Regenerative Medicine. Sanjay has 25 years of global experience in start-ups, biotech, large pharma and medical devices including 10 years in the Johnson & Johnson family of companies, culminating as VP, R&D Pharmaceuticals, Asia-Pacific and Japan. Dr. Batra has been directly involved in 80 clinical trials in all phases of development and commercialization. Hope you enjoyed this episode of Talent Talks! Tune in biweekly as we sit down with executives to hear how they acquire talent for their companies. Check out the links below to get additional information: Sanjay's LinkedIn: https://www.linkedin.com/in/sanjay-ba... VIAS Partners Website: https://viaspartners.com/ GTS Scientific Website: https://gtscareers.com/ Connect with Robb: https://www.linkedin.com/in/r-hoylegts/

Anthony Atala, MD (the G. Link Professor and Director of the Wake Forest Institute for Regenerative Medicine, and the W. Boyce Professor and Chair of Urology), joins host Lauren Richardson to discuss the results and implications of the article "A tissue-engineered uterus supports live births in rabbits" published in Nature Biotechnology.

The creators of the award-winning documentary, They Say It Can't Be Done, in partnership with the Federalist Society's Regulatory Transparency Project, present It Can Be Done Live - a conversation between entrepreneurs, regulatory experts, and noted academics around creative and bipartisan solutions to global challenges to our shared future. The second of four panel events, It Can Be Done Live: The Future of Our Health, took place on September 17th, 2020.We are in the throes of a global pandemic that threatens the lives of millions and the way of life for billions more. Our healthcare systems are stretched to their limits. At the same time, innovations are being developed that could move us from treatments to outright cures. How do we ensure that these advancements are safe and effective, but not needlessly delayed when we need them most? The panelists will explore the potential of human ingenuity to solve these problems and the conditions necessary to make those solutions a reality. We say it can be done.Featuring:Julie Allickson, Chief Manufacturing Development Center Officer, Wake Forest Institute for Regenerative MedicineBetsy McCaughey, Chairman, Committee to Reduce Infection DeathsJoshua Sharfstein, Vice Dean for Public Health Practice and Community Engagement, Bloomberg School of Public Health, Johns Hopkins UniversityDan Troy, Chief Business Officer, Chief Administrative Officer, and General Counsel, ValoModerator: Christina Sandefur, Executive Vice President, Goldwater InstituteIntroduction: Nathan Kaczmarek, Vice President & Director, Regulatory Transparency Project and Article I Initiative, The Federalist Society* * * * * As always, the Federalist Society takes no position on particular legal or public policy issues; all expressions of opinion are those of the speaker. About The Film:They Say It Can't Be Done is a documentary that explores how innovation can solve some of the world’s largest problems. The documentary tracks four companies on the cutting edge of technological solutions that could promote animal welfare, solve hunger, eliminate organ wait lists & reduce atmospheric carbon.

The creators of the award-winning documentary, They Say It Can't Be Done, in partnership with the Federalist Society's Regulatory Transparency Project, present It Can Be Done Live - a conversation between entrepreneurs, regulatory experts, and noted academics around creative and bipartisan solutions to global challenges to our shared future. The second of four panel events, It Can Be Done Live: The Future of Our Health, took place on September 17th, 2020.We are in the throes of a global pandemic that threatens the lives of millions and the way of life for billions more. Our healthcare systems are stretched to their limits. At the same time, innovations are being developed that could move us from treatments to outright cures. How do we ensure that these advancements are safe and effective, but not needlessly delayed when we need them most? The panelists will explore the potential of human ingenuity to solve these problems and the conditions necessary to make those solutions a reality. We say it can be done.Featuring:Julie Allickson, Chief Manufacturing Development Center Officer, Wake Forest Institute for Regenerative MedicineBetsy McCaughey, Chairman, Committee to Reduce Infection DeathsJoshua Sharfstein, Vice Dean for Public Health Practice and Community Engagement, Bloomberg School of Public Health, Johns Hopkins UniversityDan Troy, Chief Business Officer, Chief Administrative Officer, and General Counsel, ValoModerator: Christina Sandefur, Executive Vice President, Goldwater InstituteIntroduction: Nathan Kaczmarek, Vice President & Director, Regulatory Transparency Project and Article I Initiative, The Federalist Society* * * * * As always, the Federalist Society takes no position on particular legal or public policy issues; all expressions of opinion are those of the speaker. About The Film:They Say It Can't Be Done is a documentary that explores how innovation can solve some of the world’s largest problems. The documentary tracks four companies on the cutting edge of technological solutions that could promote animal welfare, solve hunger, eliminate organ wait lists & reduce atmospheric carbon.

The creators of the award-winning documentary, They Say It Can't Be Done, in partnership with the Federalist Society's Regulatory Transparency Project, present It Can Be Done Live - a conversation between entrepreneurs, regulatory experts, and noted academics around creative and bipartisan solutions to global challenges to our shared future. The second of four panel events, It Can Be Done Live: The Future of Our Health, took place on September 17th, 2020.We are in the throes of a global pandemic that threatens the lives of millions and the way of life for billions more. Our healthcare systems are stretched to their limits. At the same time, innovations are being developed that could move us from treatments to outright cures. How do we ensure that these advancements are safe and effective, but not needlessly delayed when we need them most? The panelists explored the potential of human ingenuity to solve these problems and the conditions necessary to make those solutions a reality. We say it can be done.Featuring:- Julie Allickson, Chief Manufacturing Development Center Officer, Wake Forest Institute for Regenerative Medicine- Betsy McCaughey, Chairman, Committee to Reduce Infection Deaths- Joshua Sharfstein, Vice Dean for Public Health Practice and Community Engagement, Bloomberg School of Public Health, Johns Hopkins University- Dan Troy, Chief Business Officer, Chief Administrative Officer, and General Counsel, Valo- [Moderator] Christina Sandefur, Executive Vice President, Goldwater InstituteVisit our website - www.RegProject.org - to learn more, view all of our content, and connect with us on social media.

The creators of the award-winning documentary, They Say It Can't Be Done, in partnership with the Federalist Society's Regulatory Transparency Project, present It Can Be Done Live - a conversation between entrepreneurs, regulatory experts, and noted academics around creative and bipartisan solutions to global challenges to our shared future. The second of four panel events, It Can Be Done Live: The Future of Our Health, took place on September 17th, 2020.We are in the throes of a global pandemic that threatens the lives of millions and the way of life for billions more. Our healthcare systems are stretched to their limits. At the same time, innovations are being developed that could move us from treatments to outright cures. How do we ensure that these advancements are safe and effective, but not needlessly delayed when we need them most? The panelists explored the potential of human ingenuity to solve these problems and the conditions necessary to make those solutions a reality. We say it can be done.Featuring:- Julie Allickson, Chief Manufacturing Development Center Officer, Wake Forest Institute for Regenerative Medicine- Betsy McCaughey, Chairman, Committee to Reduce Infection Deaths- Joshua Sharfstein, Vice Dean for Public Health Practice and Community Engagement, Bloomberg School of Public Health, Johns Hopkins University- Dan Troy, Chief Business Officer, Chief Administrative Officer, and General Counsel, Valo- [Moderator] Christina Sandefur, Executive Vice President, Goldwater InstituteVisit our website - www.RegProject.org - to learn more, view all of our content, and connect with us on social media.

You're listening to the September episode of 3 Minute 3Rs.The papers behind the pod:1. Multicellular 3D Neurovascular Unit Model for Assessing Hypoxia and Neuroinflammation Induced Blood-Brain Barrier Dysfunction. Scientific Reports https://www.nature.com/articles/s41598-020-66487-82. Automated and rapid self-report of nociception in transgenic mice. Scientific Reports https://www.nature.com/articles/s41598-020-70028-83. Zebrafish as an alternative animal model in human and animal vaccination research Laboratory Animal Research https://labanimres.biomedcentral.com/articles/10.1186/s42826-020-00042-4 Transcript: It's the 3rd Thursday of September, and you're listening to 3 Minute 3Rs, your monthly recap of efforts to replace, reduce, and refine the use of animals in research. This month, we'll let mice do the talking and hear about using zebrafish to study vaccines. But let's start with an update on an organoid.[NC3Rs] Back in 2018, Goodwell Nzou and colleagues from the Wake Forest Institute for Regenerative Medicine in the United States published their microscopic replica of the human brain, formed from the six major neural cell types including neurons and immune cells. This miniature organ, or organoid, not only promoted the formation of a blood brain barrier, the resultant barrier was also functional.Fast forward to today, and in a publication in Scientific Reports, Nzou et al have demonstrated how this platform could be used in drug screening. Disruption of the blood brain barrier in neurological disorders, such as ischaemic stroke, is common, exacerbating the injury to the brain and contributing to cognitive impairment. By culturing the organoid in hypoxic conditions, replicating low oxygen resultant from a stroke, they were able to show expression of proteins critical for blood brain barrier function were altered, leaving the barrier disrupted and leaky. Inducing ischaemic stroke in rodents is associated with significant welfare concerns, including death, weight loss, sensorimotor defects and seizures. Using organoids can replace some of these experiments in disease modelling and therapeutic development, so this new publication could have big implications for the 3Rs. You can find out more by following the link in the description.[Lab Animal] Next, some self-reporting of pain. Mice are inevitably used to study the mechanisms underlying nociception, with the goal of better understanding pain in people and how to treat it. Many studies rely on reflex assays, but interpreting these can be subjective and there's uncertainty about what the mice are feeling and reacting to. This can limit study of the neuronal pathways involved and the affective components of pain perception.A new study in the journal Scientific Reports presents an assay in which transgenic mice learn to self-report exposure to a nociceptive stimulus. The mice, head fixed in the current study, were trained to lick a water spout in response to optogenetic stimulation of heat-sensing neurons in their hind paw. The authors suggest that self-reporting may provide a quicker read-out of nociception that may better reflect the animals' affective state, and hopefully help make results with the mice more translationally relevant. And we'll finish with a topic that's likely on many of our minds: vaccines.[NA3RsC] You are probably aware of the recent push to develop a vaccine for COVID-19. Before these vaccines are given to people... See acast.com/privacy for privacy and opt-out information.

Dr. Kenneth L. Koch is a practicing physician, professor of gastroenterology at Wake Forest University, and professor at the Wake Forest Institute for Regenerative Medicine. He’s been on numerous institutional, divisional, and national committees and boards, and has authored hundreds of papers and book chapters during his career. His latest book is called, Nausea and Vomiting: Diagnosis and Treatment, which he co-edited and co-authored. Considering iboga is commonly thought of and experienced as purgative, I thought it imperative to know what happens to our bodies when we vomit in general, but more importantly, while during iboga experiences. Topics of our discussion include: what happens to the body when one eats wood; how the notion of disgust from taste and smell can cause nausea which can lead to vomiting; the gut as a primitive and protective warning system; how the body chooses from which end (e.g. mouth or anus) to expel noxious foreign agents; iboga is commonly referred to as a medicine, so how does the body know whether something is a medicine or a toxin; “optokinetic nystagmus” phenomenon and how psychedelics likely produce states similar to motion sickness, which lead to vomiting. Also, please visit my Podcast Supplements article regarding afterthoughts of Kenneth and I's conversation (https://amhouot.com/65-ep2-6_the-root-of-vomiting_kenneth-l-koch/).CONNECTTwitter (https://twitter.com/AMhouot)LinkedIn (https://www.linkedin.com/in/amhouot/)Academia (https://independent.academia.edu/AMHouot)ResearchGate (https://www.researchgate.net/profile/Am_Houot)DISCLAIMERIBOGANAUTICS podcast is for informational and educational purposes only. Efforts are made to broadcast correct information, but no guarantee is given regarding the accuracy of any statements or opinions. Contributors are not responsible for any damages arising from podcast consumption. Iboga has potential psychosomatic risks and therefore is not suitable for everyone. If wanting to consume iboga, seek out countries where it is administered legally and under professional supervision. Views discussed are not substitute for medical advice nor should be construed as best practice. Comments, suggestions, or correction of errors are welcome considering psychedelic science and related fields steadily advance.

Tissue Engineering, Regenerative Medicine, Creativity and Spirituality Professor David Williams' contributions to biomaterials, medical devices and tissue engineering impact all of our lives. Many of us might receive an implant or medical device at some point, but chances are we already know clients or loved ones with pacemakers, heart valves, hip replacements, etc. This is where the groundbreaking research of David Williams affects us all. Scientist and shaman: friends from different walks of life share a deep conversation. Take a glimpse into the life of a world-renowned scientist. This interview is a deep dive into topics such as science, ethics, spirituality, poetry and creativity. Professor David Williams has had 50 years experience in the fields of biomaterials, medical devices and tissue engineering, gained during appointments at the University of Liverpool in the UK, and more recently at various positions around the world. During his career, he has published over 30 books and 420 papers: his latest book, Essential Biomaterials Science, was published by Cambridge University Press in June 2014. He was global President of the Tissue Engineering & Regenerative Medicine International Society from 2013-2015. While retaining the title of Emeritus Professor at Liverpool, he is currently Professor and Director of International Affairs, Wake Forest Institute of Regenerative Medicine, North Carolina, USA. In addition, he is a Visiting Professor in the Chris Barnard Department of Cardiothoracic Surgery, Cape Town, South Africa. David's poetry book, A Decade of Transition: A Collection of the Poems of David Williams, is available on Amazon. Contact David at williamsdavid44@gmail.com  I love so many of David's poems, but I chose to share this one, since the topic is so relevant to our global situation. Silence is Complicity  The mute poet street Silently leads to unspoken words Scribed on the pavement’s feet Understood by mice and birds Those without tongues can still tweet Passions have to be stirred The corrupting lies that each day greet Us cannot be shelved as if not heard No difference can I make, an idea you should eat Then regurgitate with bile, a disgusting curd And spew out your righteousness, complete With honor, truth, feeling, anger unfurled Silence is complicity, as if brains effete Turn off with ease the almighty absurd Winston-Salem, NC © David Williams 2018 Links Essential Biomaterials Science available on Amazon A Decade of Transition: A Collection of the Poems of David Williams available on Amazon Thank you for much for supporting this podcast at www.patreon.com/evangelinehemrick

For more delicious news, go to www.GoodNewsGoodPlanet.com, and scroll to bottom for more ways to find the feel good stuff!* 3D PRINTED BODY PARTS Organ matches can be hard to come by. Patients typically wait for transplants for months, even years, sometimes dying before receiving them. But now there are companies combating the life-threatening organ shortage with 3D printing. The process is called "Bioprinting" and it uses human tissue cells as “ink”. It actually isn't a new idea. 3D printers can already make human skin and even retinas. But the method has been limited to small, thin tissues that lack blood vessels. New 3D printing technologies could soon change that. The Wake Forest Institute for Regenerative Medicine is creating artificial ears. A hydrogel scaffold is printed and then covered in skin and cartilage cells. These cells propagate, forming an ear-like structure. The original scaffold biodegrades, leaving the newly formed ear behind. By using the patient’s own cells, the organ has less chance of rejection once transplanted. United Therapeutics in New Hampshire is using a similar method to create lungs. A collagen infrastructure is 3D printed and then impregnated with human cells to animate it. The process, called "recellularization" is still in its early stages and not without challenges. The more complex an organ, the more difficult the task. Organs may someday be manufactured in large numbers, not only solving the organ shortage, but also reshaping our life spans. Imagine getting a new heart and lungs when your original ones give out. The future possibilities are exciting, though much further research and testing are still needed. While printing a 3D brain is a long way off, Sharon Presnell—chief scientist of Organovo whose company is 3D printing thin sheets of liver—says, “We all think it’s going to be possible at some point in the future. Where we differ, is on how long it will take.” *Hungry for more of the Good Stuff? Search "Good News Good Planet" on YouTube, Instagram, Patreon, Alexa and wherever you listen to your favorite podcasts.

Researchers from Wake Forest Institute for Regenerative Medicine (WFIRM) used an integrated tissue-organ printer (ITOP) to 3D-bioprint a trachea. Researchers have already 3D-printed tracheal splints and scaffolds to grow tissue-engineered tracheas, but this is the first trachea with various functional materials. Previous attempts failed because they only used regenerated cartilage tissue. According to the researchers, they weren't strong enough to hold the airways open or provide the necessary flexibility.These constructs were printed with cartilage and smooth muscle regions at the same time using biodegradable polyester material and stem cell hydrogels. The cartilage provides enough support to avoid collapse, and the smooth muscle offers the needed flexibility.The proof-of-concept could one day lead to custom patient care for those suffering from tracheal stenosis, or the narrowing of the windpipe. Now, these patients need breathing tubes. In the future, medical professionals could use the patient's medical records to print biocompatible replacements.Next, the team will test long-term functionality to make sure the 3D-bioprinted tracheas maintain their initial characteristics. WFIRM has done some impressive work in the past, everything from 3D printing human ears to growings livers, kidneys, and even anal sphincters.

Read the full blog here: https://texasback.com/the-future-of-spine-surgery-will-involve-3d-printing/ There is an interesting intersection at work between the disciplines of mechanical engineering and orthopedic surgery. For example, spine surgeon Dr. Michael Hisey of Texas Back Institute earned his undergraduate degree in mechanical engineering from The California Institute of Technology. Of course, he then went on to medical school and specialized in orthopedic surgery, but his fascination with engineering continues to this day. This partially explains his interest in the 3D printing of medical devices. A Brief History of 3D Printing While it seems that 3D technology has just recently burst on the scene, in fact, it has been around since 1981. It was originally known as “additive manufacturing” and was invented by Hideo Kodama of Nagoya Municipal Industrial Research Institute in Japan. The first medical application of 3D printing occurred in 1999 when scientists at Wake Forest Institute for Regenerative Medicine printed synthetic scaffolds of a human bladder and then coated them with the cells of human patients. The newly generated tissue was then implanted into the patients with little to no chance that their immune systems would reject them, as they were made of their own cells. The market for 3D printing is growing rapidly. One example of this growth is Essentium Inc., a Texas-based 3D printing company that is transforming additive manufacturing for use in a broad range of industries. Read the full blog here: https://texasback.com/the-future-of-spine-surgery-will-involve-3d-printing/

This is a keynote session from DPharm 2018. Dr Atala, a renowned key opinion leader on the topic of regenerative medicine, brings the DPharm audience a fascinating presentation on how it's possible to reduce the number of patients needed in clinical trials with the advancement of regenerative medicine, and how regenerative medicine can improve accuracy and speed up the clinical trial process. Speaker: Anthony Atala, MD, Director, Wake Forest Institute for Regenerative Medicine The 9th annual DPharm conference will take place on September 17-18, 2019 in Boston, MA. Learn more at theconferenceforum.org.

WFIRM talks to Dr. John Jackson, an Associate Professor at the Wake Forest Institute for Regenerative Medicine about bioprinting for the wounded warrior including corporal tissue as well as ear hair follicle regeneration.

When organs like kidneys and livers fail, it can be scary—especially for kids. But the science of regenerative medicine, where new organs are created from a patient's own cells and tissue, is a promising new field in medicine. Dr. Anthony Atala is the Director of the Wake Forest Institute for Regenerative Medicine and he joins Nate on this episode to talk about how new organs can be created in the lab using 3D printers.

A lab at The Wake Forest Institute for Regenerative Medicine in Winston-Salem, North Carolina, is printing organs using human cells in a biodegradable frame allowing for nerves and blood vessels to grow into the organ and function normally. We go inside this lab that is bringing the science of regenerative medicine to a new level. SciTech Now airs weekly on public television stations nationwide (check local listings). For more for more stories like this visit scitechnow.org Like us on Facebook: facebook.com/scitechnow Follow us on Twitter: @SciTechNow Join the conversation with #SciTechNow

This episode we take on a future full of bioprinted replacement organs. You asked for more hopeful futures, this is about as hopeful as they get!     We start by hearing a bit about what the current organ donation market is like from Christine Gentry, who donated a kidney to a stranger. Then we talk to Dr. Anthony Atala,  the Director of the Wake Forest Institute for Regenerative Medicine and of the world’s leading regenerative medicine specialists. Dr. Atala has implanted organs grown from the cells of patients themselves in clinical trials. Then Kelly and Zach Weinersmith join us to talk about what they learned while writing a chapter about bioprinting for their new book Soonish: Ten Emerging Technologies That'll Improve and/or Ruin Everything. And finally, we get an impassioned indictment of 3D printing file formats from Meghan McCarthy, Project Lead for the NIH 3D Print Exchange.    Further reading:    Organ Donation Statistics  Neural and cognitive characteristics of extraordinary altruists  Boston woman's donation creates 3rd-longest kidney transplant chain, saving 28 people  The Doctor and the Salamander  How An Economist Helped Patients Find The Right Kidney Donors  TED Talk: Printing a Human Kidney  Rebuilding the Breast  Soonish: Zach and Kelly Weinersmith on 10 technologies that will change everything  Online Course Bioprinting: 3D Printing Body Parts  Scientists 3-D Print Mouse Ovaries That Actually Make Babies    If you’re interested in becoming a living organ donor and want to know what it’s like, you can get in touch with Christine Gentry. Her email is christine.gentry at gmail.com, and she’s all about helping people understand donation.     Flash Forward is produced by me, Rose Eveleth. The intro music is by Asura and the outtro music is by Hussalonia. Our intro future voices were skillfully provided by Alyssa Mondelli, BW and Josh Kirby. The music from the intro was by Unheard Music Concepts, PC III and Soft and Furious. The episode art is by Matt Lubchansky.     If you want to suggest a future we should take on, send us a note on Twitter, Facebook or by email at info@flashforwardpod.com. We love hearing your ideas! And if you think you’ve spotted one of the little references I’ve hidden in the episode, email us there too. If you’re right, I’ll send you something cool.     And if you want to support the show, there are a few ways you can do that too! Head to www.flashforwardpod.com/support for more about how to give. But if that’s not in the cards for you, you can head to iTunes and leave us a nice review or just tell your friends about us. Those things really do help.     That’s all for this future, come back next time and we’ll travel to a new one. Learn more about your ad choices. Visit megaphone.fm/adchoices

Congressional candidate Mark Walker talks about his platform in Election 2014. The College of Textiles at NCSU is developing "smart" fabrics. And researchers at the Wake Forest Institute for Regenerative Medicine are growing synthetic organs to test new drug therapie

PRE-RECORDED TUESDAY, MARCH 29, 2014 3:30 PM PST Our incredible special guests today are: Joan F. Schanck, MPA William Hinman, CFRE, MBA Kelly Milukas, RMF Commissioned Artist  Katie Jackson, VP, Help 4 HD International SUBJECT Tonight we have four amazing and incredible guests here to talk about Regenerative Medicine Foundations upcoming Conference and Gallery Opening event which will be held at the Claremont Hotel in Berkeley, CA (May 5-7). We have Joan Schank, MPA, Academic Research Program office at Wake Forest Institute for Regenerative Medicine and Director of Education for the Regenerative Medicine Foundation. We have Bill Hinman, CFRE, MBA and Executive Director of the National Regenerative Medicine Foundation. Its mission is to encourage and promote unbiased efforts which accelerate the discovery and development of new regenerative medicine therapies for patients. Then we have Kelly Milukas, from Tiverton, RI, an amazing and talented award winning, multimedia, modern fine artist. She has been commissioned by RMF since 2010 to present her art exhibit “Keys to the Cure”. Visit her beautiful textural and pastel works atwww.kellymilukas.com. Katie Jackson, VP H4HDI and patient advocate extraordinaire is also with us tonight. She will be one of several honored panel speakers at the Conference Gallery Opening Event on May 5th. It's going to be an awesome show today!

The Nobel Prize in Physiology or Medicine 2014 was awarded with one half to John O'Keefe and the other half jointly to May-Britt Moser and Edvard I. Moser "for their discoveries of cells that constitute a positioning system in the brain".The Nobel Prize in Physics 2014 was awarded jointly to Isamu Akasaki, Hiroshi Amano and Shuji Nakamura "for the invention of efficient blue light-emitting diodes which has enabled bright and energy-saving white light sources".The Nobel Prize in Chemistry 2014 was awarded jointly to Eric Betzig, Stefan W. Hell and William E. Moerner "for the development of super-resolved fluorescence microscopy".A team of scientists took soil samples at 596 sites across New York's Central Park. They analysed the soil samples an discovered 167,000 different kinds of microbes, the vast majority of which were unknown to science.The characteristics of a previous mate can affect the attributes of a fruit fly's offspring. Even if the previous mate is not the genetic father of the offspring.Researchers at the Wake Forest Institute for Regenerative Medicine in Winston-Salem, North Carolina are developing artificial penises developed from a patient's own cells. The team is hoping to receive approval from the US FDA to begin human testing the lab-grown penises within five years.

TUESDAY, MARCH 29, 2014 3:30 PM PST Our incredible special guests today are: Joan F. Schanck, MPA William Hinman, CFRE, MBA Kelly Milukas, RMF Commissioned Artist  Katie Jackson, VP, Help 4 HD International SUBJECT Tonight we have four amazing and incredible guests here to talk about Regenerative Medicine Foundations upcoming Conference and Gallery Opening event which will be held at the Claremont Hotel in Berkeley, CA (May 5-7). We have Joan Schank, MPA, Academic Research Program office at Wake Forest Institute for Regenerative Medicine and Director of Education for the Regenerative Medicine Foundation. We have Bill Hinman, CFRE, MBA and Executive Director of the National Regenerative Medicine Foundation. Its mission is to encourage and promote unbiased efforts which accelerate the discovery and development of new regenerative medicine therapies for patients. Then we have Kelly Milukas, from Tiverton, RI, an amazing and talented award winning, multimedia, modern fine artist. She has been commissioned by RMF since 2010 to present her art exhibit “Keys to the Cure”. Visit her beautiful textural and pastel works at www.kellymilukas.com. Katie Jackson, VP H4HDI and patient advocate extraordinaire is also with us tonight. She will be one of several honored panel speakers at the Conference Gallery Opening Event on May 5th. It's going to be an awesome show today!

George Christ, PhD visits Regenerative Medicine Today and shares his vision on regenerative medicine. Dr. Christ is a professor at Wake Forest University and the Wake Forest Institute for Regenerative Medicine. Dr. Christ's research interests are in the area of functional genomics, that is, establishing a verifiable link between changes in gene expression [...]