Podcasts about United Therapeutics

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Best podcasts about United Therapeutics

Latest podcast episodes about United Therapeutics

The Road from Carmel
Raymond Dwek CBE FRS (1949-60)

The Road from Carmel

Play Episode Listen Later Dec 13, 2024 43:52


Joining Jill and Doron on the 34th episode of the podcast, the sixteenth of our second season, to tell us his story is esteemed British scientist Professor Raymond Dwek, who attended Carmel College from 1949 to ‘60, accompanied by his older brother Joe.  Both brothers would go on to become governors of Carmel. Raymond studied Chemistry at Manchester University and completed his DPhil at Oxford University.  During this time, both Raymond and his wife Sandra also taught at Carmel.  He became Professor of Glycobiology, a field he was instrumental in creating, in the Department of Biochemistry at Oxford, which he headed for several years.  He is an emeritus fellow of Exeter College at Oxford and emeritus director of the Oxford Glycobiology Institute, which he founded.  The institute gave rise to a company that became publicly listed and developed a drug - eventually approved worldwide - for Gaucher disease, a rare, genetic metabolic disorder with a much enhanced incidence among Ashkenazi Jews.  A second company that arose from the institute was taken over by United Therapeutics, a $15 billion NASDAQ-listed US biotech company, of which Raymond is a Director.  He has authored several scientific volumes and over 600 published papers, has formally advised scientific institutions in Israel, the United States and China, was appointed Commander of the Order of the British Empire for services to scientific collaboration between the United Kingdom and Israel, and was elected a Fellow of the Royal Society.  He and Sandra live in Oxford, and have four children, including a daughter, Deborah, who also attended Carmel. Hear Raymond talk about the Dwek dynasty, an unexpected guest at a midnight feast, the best teacher he ever knew, his brother Joe's ‘special diet', building Ben Gurion University from a camel market, his CBE award by Princess Anne, and the secret to a long and happy marriage. Thank you, Professor Raymond Dwek, for turning us again to Carmel days!   Dedication: at Raymond's request, this episode is dedicated to his daughter Deborah, his brother Joe, and Joe's son Jonathan, all of whom went to Carmel, along with all the other members of the Dwek family that did so too.    Personal mentions in this episode: Rabbi Dr. Kopul Rosen (Headmaster) Bella Rosen (Co-founder) Rabbi Jeremy Rosen (Headmaster) Romney Coles (Chemistry) Dr. David Stamler (Headmaster) John Bunney (Physics) Ron Evans (Mathematics) Murray Roston (English & Hebrew) Ted Fields (Rowing) Malcolm Shifrin (Librarian) Dr. Alexander Tobias (Jewish Studies) Meir Gertner (Jewish Studies) Philip Skelker (Headmaster) Joe Dwek Deborah Dwek David Sheldon Jerrold Roston Jonathan Dwek   Feel free to leave a comment letting us know what you liked about this episode, and rate us on your favorite podcast platform

Green Rush Podcast
Alternatively Speaking: Lou Reese, Next-Gen Vaccines

Green Rush Podcast

Play Episode Listen Later Nov 21, 2024 55:45


Welcome to the Green Rush, a weekly conversation at the intersection of cannabis, psychedelics, the capital markets, and culture, produced by KCSA Podcast Labs. Today, we have a special episode featuring our newest production, Alternatively Speaking. In our debut season, we're diving into a revolutionary concept in health span, longevity, and healthcare. We sat down with Lou Reese, co-founder and Vice Chairman of Vaxxinity, a purpose-driven biotechnology company pioneering a new class of medicines aimed at disrupting existing treatments for chronic diseases. Founded in 2014 alongside his wife and CEO, Mei Mei Hu, Vaxxinity is at the forefront of developing "next generation" vaccines for chronic conditions such as Alzheimer's, Parkinson's, heart disease, and migraine. Lou Reese also serves on the Executive Committee of United Biomedical, Inc. (UBI), a multinational biopharmaceutical organization focused on developing diagnostics and immunotherapeutics for global health improvement. Lou was a director at ShenLian Biotech, one of the largest animal health companies in China, and co-founded an investment firm with ventures spanning real estate, energy, hospitality, and life sciences. Podcast Highlights: Introduction & Lou Reese's Background (3:00): Lou's journey and his mission to eliminate global suffering. Synthetic Peptide Technology (10:15): Discussion of Vaxxinity's innovative approach to vaccine development. Active Immunotherapy Medicines (18:30): Vaxxinity's work on developing active immunotherapy medicines. Parkinson's Disease Breakthrough (23:45): Promising results from Vaxxinity's Parkinson's trials. Company Restructuring (32:00): Vaxxinity's decision to delist and deregister, and plans for becoming a B Corp. Army of Compassion (41:30): Global prevention trial for Alzheimer's and partnership with former Governor David Beasley. Future of Healthcare (48:45): Lou's vision for affecting billions of lives and revolutionizing healthcare spending. Social Media: Lou Reese's LinkedIn: https://www.linkedin.com/in/lou-reese-6b54504/  X: https://x.com/notloureese  Other Links/Mentions/Resources: Vaxxinity's official website: https://www.vaxxinity.com/  World Food Programme: https://www.wfp.org/  Mayo Clinic: https://www.mayoclinic.org/  UT Health: https://www.uthscsa.edu/  Amprion: https://www.amprionme.com/  United Therapeutics: https://www.unither.com/  Show Credits: This episode was hosted by Lewis Goldberg of KCSA Strategic Communications.  Special thanks to our Program Director, Shea Gunther, and Executive Producer, Maria Petsanas. You can learn more about how KCSA can help your cannabis and psychedelic companies by visiting www.kcsa.com or emailing AltSpeaking@kcsa.com. You can also connect with us via our social channels: X: @KCSAPodcastLabs Instagram: @KCSAPodcastLabs LinkedIn: https://www.linkedin.com/company/kcsapodcastlabs/

Airplane Geeks Podcast
824 Robinson Hydrogen-Powered Helicopter

Airplane Geeks Podcast

Play Episode Listen Later Nov 13, 2024 59:36


A Robinson hydrogen helicopter, Boeing machinists' new contract, furloughed Boeing staff and impending layoffs, Jeppesen possibly for sale, incendiary devices at DHL, Boom Supersonic XB-1 test flight, shots fired at Spirit, and air tanker minimum drop height. Aviation News Unither Bioelectronics Signs Agreement with Robinson Helicopter Company Unither Bioelectronics Inc. (UB) and Robinson Helicopter Company have entered into a strategic collaboration agreement to accelerate UB's development and certification of hydrogen-powered helicopters based on Robinson R44 and R66 models. UB is a subsidiary of United Therapeutics Corporation and CEO Martine Rothblatt said “...we look forward to using protons from green hydrogen to drive the membrane-based fuel cell powerplants in our Robinson R66 organ delivery electric helicopters.” Robinson R66 (Courtesy Robinson Helicopter Company) United Therapeutics adds hydrogen to its electric helicopter plans United Therapeutics is a biotechnology company that says it has been working on a hydrogen-powered R44 prototype for about a year and a half, and its first hover is “hopefully imminent.” In 2016, United Therapeutics began developing a battery-electric-powered Robinson R44 through a partnership with Tier 1 Engineering. A Guinness World Record was set in 2018 for the farthest distance traveled by an electric helicopter—30 nautical miles. UT also has partnerships with eVTOL developers EHang and Beta Technologies. Boeing strike ends as workers accept new contract The Machinists Union members accepted the contract with Boeing. Workers will get pay rises over four years. The union had demanded a 40% wage increase and restoration of a defined-benefit pension. The 38% wage increase plus a $12,000 bonus amounted to a 40% increase. The new contract does not restore the pension but promises that the next Boeing airplane will be built in the Seattle area. According to some analysts, the strike cost Boeing around $100 million a day in lost revenue. Boeing to repay furloughed staff, proceed with job cuts During the strike, Boeing furloughed some salaried employees, but CEO Kelly Ortberg said they would be repaid for lost wages. At the same time, Ortberg said a 10% cutback of the global workforce would proceed. A Society of Professional Engineering Employees in Aerospace (SPEEA) spokesperson said it was informed that 60-day notices of job losses would be issued to its members on Nov. 15, 2024. SPEEA has reached a tentative agreement with Spirit AeroSystems on a new four-year contract that offers at least a 19% pay increase over four years. It includes provisions for greater increases if needed to keep up with labor market conditions, and a guaranteed minimum 5% bonus in the spring of 2025. Report Says Boeing Eyeing Sale Of Jeppesen As Boeing CEO Kelly Ortberg looks to sell off non-core assets, Bloomberg quotes unnamed sources as saying Jeppesen is a candidate. Jeppesen is the world's largest provider of aviation charts and air navigation materials. Boeing may be looking to get $6 billion for the company. Boeing paid bought Jeppesen in 2000 for $1.5 billion. Boeing also owns ForeFlight but the Bloomberg report does not mention that company, Russia Suspected of Plotting to Send Incendiary Devices on U.S. Bound Planes Electric massagers that held a magnesium-based flammable substance were shipped via DHL from Lithuania and ignited at DHL logistics hubs in Germany and England. Security officials say this was part of a covert Russian operation seeking to start fires on aircraft flying to the U.S. and Canada. Boom Supersonic's XB-1 jet sets new speed record during 7th test flight Boom Supersonic plans ten subsonic test flights of their XB-1 supersonic demonstrator aircraft before supersonic speed testing begins. Boom has now completed the seventh of those ten subsonic test flights reaching an altitude of 23,015 feet (7,

Biotech Bytes: Conversations with Biotechnology / Pharmaceutical IT Leaders
How Tech Is Solving The Organ Shortage Problem with Shola Oyewole

Biotech Bytes: Conversations with Biotechnology / Pharmaceutical IT Leaders

Play Episode Listen Later Oct 31, 2024 35:39 Transcription Available


The organ shortage crisis is one of modern medicine's greatest challenges, but innovative technologies like 3D printing and AI are changing the game. Please visit our website to get more information: https://swangroup.net/ In this episode, I talk with Shola Oyewole, VP of Digital Innovation at United Therapeutics, to explore how they lead the charge in organ development through advanced tech. From creating genetically modified organs to personalized medicine, Shola shares his insights into the future of healthcare.Technology is reshaping healthcare in powerful ways, and United Therapeutics is proving that innovation and empathy can go hand in hand. Don't miss this inspiring episode, in which we uncover how the future of medicine is being built today.Specifically, this episode highlights the following themes:Tackling the organ shortage through 3D printing and genetic modificationAI and data governance challenges in healthcareFostering innovation through teamwork and open competitionsLinks from this episode:Get to know more about Shola Oyewole:https://www.linkedin.com/in/sholaoyewoleLearn more about United Therapeutics: https://www.unither.comRead NPR's Insightful Article on Organ Transplants: https://www.npr.org/2024/04/13/1244583164/patients-die-every-day-waiting-for-organ-transplants-the-problem-isnt-a-lack-ofCheck Out the Netflix Documentary on "We Are the World": https://www.comingsoon.net/movies/trailers/1477397-the-greatest-night-in-pop-trailer-previews-netflix-documentary-about-the-making-of-we-are-the-world-songRead Forbes' Article on Martine Rothblatt: https://www.forbes.com/sites/richardjchang/2024/07/18/meet-the-new-biotech-martine-rothblatt-billionaire-putting-pig-hearts-in-humansGet to know more about Steven Swan: https://www.linkedin.com/in/swangroup

20-Minute Health Talk
Newsroom: Northwell Health announces the 2024 Constellation Forum

20-Minute Health Talk

Play Episode Listen Later Sep 25, 2024 3:08 Transcription Available


Listen to this Northwell Newsroom article about the 7th annual Northwell Health Constellation Forum, taking place on October 17, 2024. This leading innovation summit brings together healthcare visionaries, investors and disruptors for a day of discussion and collaboration. Registrants can join virtually or in person in New York City starting at 9 a.m. EST.  Register here. Speakers include industry leaders from United Therapeutics, IBM, the American College of Physicians, the FDA, and more. Andrea Califano, PhD, president, CZ Biohub New York, Chan Zuckerberg Initiative Douglas Kelly, MD, deputy center director for science, chief scientist, Center for Devices & Radiological Health (CDRH), Food and Drug Administration (FDA) Arvind Krishna, chairman and CEO, IBM Geoff Ling, MD, PhD, CEO, Ling and Associates, LLC, and former founding director of the Biological Technologies Office at the Defense Advanced Research Projects Agency (DARPA) Darilyn V. Moyer, MD, executive vice president and CEO, American College of Physicians Shola Oyewole, senior vice president, Innovative Technology, United Therapeutics Murthy Simhambhatla, PhD, president and CEO, SetPoint Medical Craig Venter, PhD, founder, J. Craig Venter Institute Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. Interested in a career at Northwell Health? Visit http://bit.ly/2Z7iHFL and explore our many opportunities.   Facebook –   / northwellhealth   Instagram -   / northwellhealth   X - https://www.x.com/northwellhealth LinkedIn - https://www.linkedin/northwellhealth

The 7investing Podcast
United Therapeutics: Leading a Biotech Revolution

The 7investing Podcast

Play Episode Listen Later Sep 4, 2024 10:32


United Therapeutics (Nasdaq: UTHR) is a very smart, very innovative, and very profitable company. First it treated an untreatable disease. Now it's disrupting the entire organ transplant industry. In today's show, 7investing CEO Simon Erickson introduces United Therapeutics, describing why the company was created and its five commercially-approved drugs. He also explains how its four synthetic organ programs could disrupt the entire organ transplant market. See why United Therapeutics is a stock that should be on your radar. To join our free email list, visit 7investing.com/email.

Oral Arguments for the Court of Appeals for the Federal Circuit
United Therapeutics Corporation v. Liquidia Technologies, Inc.

Oral Arguments for the Court of Appeals for the Federal Circuit

Play Episode Listen Later Sep 3, 2024 40:43


United Therapeutics Corporation v. Liquidia Technologies, Inc.

The Tim Ferriss Show
#749: Michael Lewis and Martine Rothblatt

The Tim Ferriss Show

Play Episode Listen Later Jun 25, 2024 138:19


This episode is a two-for-one, and that's because the podcast recently hit its 10-year anniversary and passed one billion downloads. To celebrate, I've curated some of the best of the best—some of my favorites—from more than 700 episodes over the last decade. I could not be more excited. The episode features segments from episode #427 "Michael Lewis — Inside the Mind of the Iconic Writer" and episode #487 "Dr. Martine Rothblatt — A Masterclass on Asking Better Questions and Peering Into the Future."Please enjoy!Sponsors:Shopify global commerce platform, providing tools to start, grow, market, and manage a retail business: https://shopify.com/tim (one-dollar-per-month trial period)AG1 all-in-one nutritional supplement: https://drinkag1.com/tim (1-year supply of Vitamin D [and 5 free AG1 travel packs] with your first subscription purchase.)Eight Sleep's Pod 4 Ultra sleeping solution for dynamic cooling and heating: https://eightsleep.com/tim (save $350 on the Pod 4 Ultra)Timestamps:[04:13] Notes about this supercombo format.[05:16] Enter Michael Lewis.[05:54] Why Michael quit his well-paid job to become a full-time author.[12:58] Liar's Poker is a cautionary tale, not a how-to book.[15:16] On ambition and the metrics of success.[18:31] Maximizing self-satisfaction, optimizing the writing process, and learning to sing.[20:51] The value of having an impolite editor on your side.[23:52] On the merits of productive laziness.[28:13] How Michael determines if a project should proceed.[29:51] Michael's billboard.[32:45] Enter Martine Rothblatt.[33:14] Martine's appreciation for Alan Watts' book on human identity.[35:34] Martine's thoughts on AI-human coexistence in the movie Her.[36:31] BINA48 and realistic human simulations in media.[39:53] Martine's role models and inspirations.[41:20] When Martine started a biotech company to save her daughter's life.[52:44] Glaxo Wellcome's misconceptions about Martine's successful drug.[56:17] Martine's interest in satellite communication systems.[1:00:33] Promoting scientific literacy and curiosity.[1:05:20] Questioning authority and Martine's transgender journey.[1:10:28] Martine's non-binary gender identity.[1:12:34] Key decisions in Martine's transition.[1:13:28] The need for genetic information protection laws.[1:16:00] South American population and organ transplant research.[1:21:42] Vagus nerve manipulation for various therapies.[1:31:25] Martine's Alzheimer's cognitive enabler patent.[1:38:17] The Rothblatt family's "love nights" tradition.[1:43:54] The possibility of machines experiencing love.[1:49:20] Ethical considerations for future technology.[1:52:44] Current practices future generations might view as barbaric.[1:57:42] United Therapeutics' zero-carbon-footprint headquarters.[2:00:32] Refurbishing unusable lungs to save lives.[2:04:45] United Therapeutics' focus on long-term COVID-19 effects.[2:07:26] Martine's billboard.[2:08:27] Advice for finding positivity in life.[2:11:48] Parting thoughts.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Elevate Medical Affairs Podcast Channel
Medical Congresses: Optimizing Your Most Strategic Investment

Elevate Medical Affairs Podcast Channel

Play Episode Listen Later Jun 11, 2024 20:49


In this podcast, we discuss a data-driven approach for optimizing congress planning and execution. MAPS speaks with experts from United Therapeutics and Veeva for tips on finding the right events, effectively engaging the right experts, and enabling medical teams to do more with less.

I AM BIO
Biotech is Climate Tech

I AM BIO

Play Episode Listen Later Apr 9, 2024 21:27


Biotech companies are addressing climate change through innovation—from carbon neutral facilities to agricultural innovations to reduce greenhouse gas emissions. BIO was on the ground at the COP28 UN Climate Change Conference in Dubai to deliver the message that biotech is climate tech.Follow us on LinkedIn, X, Facebook and Instagram. Visit us at https://www.bio.org/

What's Happening MoCo?
What's Happening with BioTech Business? Brad L Stewart

What's Happening MoCo?

Play Episode Listen Later Mar 12, 2024 20:56


Montgomery County's Economic Develop Corporation's (MCEDC) Senior Vice President Brad L. Stewart joined the latest episode of the What's Happening MoCo podcast, which is now available. The episode centers on biotech and life sciences business in the County. Mr. Stewart will share his career journey and provide insight into the County's biotech and life sciences industry and will talk about the growth of AstraZeneca and United Therapeutics in the region.  To hear the interview and gain some tips for local entrepreneurs, listen to the What's Happening MoCo podcast via a podcast platform including Apple Podcasts Spotify, Amazon Music (ask Alexa to play the What's Happening MoCo podcast), iHeartRadio, TuneIn and others. The video version of the podcast can be viewed on the What's Happening MoCo Facebook page or on County Cable Montgomery, Xfinity Channel 996, RCN 1056 or Verizon 30.  

Pharma and BioTech Daily
Biopharma Buzz: Key Updates in Pharma and Biotech World

Pharma and BioTech Daily

Play Episode Listen Later Feb 23, 2024 2:28


Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world. On February 22, 2024, significant developments in the biopharma industry were reported. Ori Capital raised a new biotech fund to support startups working on innovative drugmaking approaches. The Biden administration pledged $100 million towards women's health research as part of an initiative led by First Lady Jill Biden. Moderna faced challenges in transitioning but pitched a new RSV shot and vaccines for the future. Novavax agreed to pay Gavi in a settlement over a COVID vaccine contract. A paper in NEJM highlighted the "remarkable" results of CAR-T therapy in treating autoimmune diseases, shedding light on its potential benefits and remaining challenges. Moderna is banking on an experimental RSV vaccine to drive future sales. The state of biosimilars in 2024 was discussed, noting that while the U.S. market had initially fallen short of expectations, more products have entered the market recently after a slow start.Moderna reported a surprise profit in Q4 despite a 43% decline in COVID-19 vaccine revenue. The company beat analyst estimates thanks to deferred payments and cost savings. Pfizer and Moderna both exceeded expectations in COVID-19 sales but face challenges with declining revenues in the future. Novavax settled a $400 million agreement with Gavi for their COVID-19 vaccine. Bristol Myers Squibb is focusing on advanced modalities to combat cancer. Protagonist published promising phase II data for a blood cancer therapy. The biopharma industry is seeing an increase in data analysts as data becomes more important. Gilead CEO O'Day was named the new board chair of PhRMA.This week's Commercialization Weekly highlights several key developments in the biopharma industry. United Therapeutics has taken the unusual step of suing the FDA over a rival's drug application, alleging that the agency is allowing rule violations. The FDA is set to review expanded use of Sarepta's Duchenne gene therapy, while Iovance prepares for the launch of its 'TIL' cell therapy after receiving approval. Astrazeneca also received a new approval for Tagrisso in lung cancer treatment. Additionally, Abbvie's proposed acquisition is facing delays due to a "second request" from the FTC. These developments showcase the ongoing challenges and advancements in the biopharma sector.

CRUSADE Channel Previews
Why Only Trump Can Restore The Big Business That Is Empire Muricah

CRUSADE Channel Previews

Play Episode Listen Later Dec 18, 2023 71:10


SPECIAL GUEST Frank Wright Website - Substack -  Pope Francis  They are going to set these Priests up with a homosexual couple and a Priest will refuse and then the games begin. This is setting up Priests to be persecuted. I have expected the worst from the Vatican these days and that is precisely what we are getting. I agree w/ you, the trouble is Rage Farming is very lucrative.  It is a dopamine loop. What are my duties and what should I be doing w/ my life? That is what we should be looking at ‘what in my life can I control' and do that first. That is rewarding. The Catholic faith doesn't exist in the Holy See only. The impressions are important, like when I wear these glasses w/ no lenses.  JB Pritzker Governor of Illinois  The transgender phenomenon.  Social Contagion - you get this through watching and listening to others in that group. This whole conceptual world, you can transform not just as running faster if you buy THESE shoes but now it is you can become another sex. It is the penuchle of consumerism.  When I wear a wig I do it in a dignified manner. You are looking to escape your depression by buying a new vagina or penis. Martine Aliana Rothblatt - who had previously been a founder of Sirius satellite radio, headed United Therapeutics and was the highest paid female CEO in the U.S. The subject of her SXSW talk was artificial intelligence and specifically "mind cloning," which included her discussion of the "mind clone" she had built of her wife Bina, known as BINA48. Among other topics, she projected a future in which robots would have constitutional rights and envisioned ways to help ease robots' potential anxiety about not being human. What is a midwit? It isn't about winning the argument but it is about displaying your own vanity. You don't have to be cleaver to get into University any longer. You listened to those ‘experts' during COVID and they were all wrong. The fantasy empire is bad for business.  If you haven't gotten any business, you can't recruit soldiers and you can't pay for the ammunition, then where is your power? The power w/ the US is mainly in the Navy right? It is going to be difficult to steal another election this time. People in the United States really don't belive in the US anymore. That is precisely what happened to the Russian Empire. 100% correct assessment by Frank Wright. If you look back at the COVID thing it penalized the wise and gave praise to the idiots. 30-40% rouge DNA - COVID vaccine Shops were shuttered, community groups and such have forever changed.

Connected With Latham
Episode 61 – Drug Pricing: New OIG Guidance Reaffirms the Seven Elements of an Effective Compliance Program

Connected With Latham

Play Episode Listen Later Dec 7, 2023 12:45


In November, the Department of Health and Human Services' Office of the Inspector General (OIG) issued new compliance program guidance that affirms OIG's long-standing focus on the seven elements of an effective compliance program, first published in 2003. In this episode of Connected With Latham, partner Chris Schott and associate Danny Machado are joined by guest Lynn Robson of United Therapeutics. They discuss how the OIG's compliance framework is relevant to drug manufacturers, how past enforcement actions can inform implementation of a compliance program, and how an effective compliance program can be beneficial in the enforcement context.   This podcast is provided as a service of Latham & Watkins LLP. Listening to this podcast does not create an attorney client relationship between you and Latham & Watkins LLP, and you should not send confidential information to Latham & Watkins LLP. While we make every effort to assure that the content of this podcast is accurate, comprehensive, and current, we do not warrant or guarantee any of those things and you may not rely on this podcast as a substitute for legal research and/or consulting a qualified attorney. Listening to this podcast is not a substitute for engaging a lawyer to advise on your individual needs. Should you require legal advice on the issues covered in this podcast, please consult a qualified attorney. Under New York's Code of Professional Responsibility, portions of this communication contain attorney advertising. Prior results do not guarantee a similar outcome. Results depend upon a variety of factors unique to each representation. Please direct all inquiries regarding the conduct of Latham and Watkins attorneys under New York's Disciplinary Rules to Latham & Watkins LLP, 1271 Avenue of the Americas, New York, NY 10020, Phone: 1.212.906.1200

The NACE Clinical Highlights Show
The APAPP Podcast Ep. 7: What's new in Pulmonary Hypertension in 2023

The NACE Clinical Highlights Show

Play Episode Listen Later Sep 12, 2023 34:36


Show NotesNACE is excited to provide you with this podcast episode from our educational collaborator, The Association of Pulmonary Advanced Practice Providers (APAPP).  APAPP is the first  association of Advanced Practice Providers (APPs), both Nurse Practitioners and Physician Assistants, who work in the field of pulmonary medicine. APAPP's mission is to work together for the advancement of the profession and for the well-being of  patients with pulmonary diseases. To learn more about APAPP and to get involved, please visit https://www.pulmapp.com.GuestMartha Kingman, FNP-C, DNP Family Nurse Practitioner in the pulmonary hypertension clinic at the University of Texas Southwestern Medical Center at Dallas. She is presently serving as sub-investigator in numerous ongoing pulmonary hypertension clinical trials. She is a member of the speakers' bureaus for Actelion, United Therapeutics, and Gilead, and she gives her time and expertise to several nursing advisory boards. Martha is an active member of the PH Professional Network, having previously served on the national conference planning committee, and she has chaired the Research and Publications Committee of the Pulmonary Hypertension Association. She currently serves on the Editorial Board of Advances in Pulmonary Hypertension, the PHA's journal.Dr. Kingman earned a bachelor's degree from Tulsa University School of Nursing in Tulsa, following which she worked in emergency department settings as a staff nurse and then as director of the ED after which she obtained her Master of Science in Nursing degree from Texas Woman's University in Dallas. When she became board certified as a Family Nurse Practitioner, she accepted the job of nurse practitioner in the pulmonary department at UTSW Medical Center and remains in that role today.  The majority of her clinical work involves the follow-up outpatient care of a large group of pulmonary hypertension patients at UTSW Medical Center. In May 2011, Dr. Kingman obtained her Doctorate in Nursing Practice from Texas Christian University.Martha has published in the area of pulmonary hypertension and has spoken at local and national conferences.  Her main area of research interest involves the safety of intravenous prostacyclins in the hospital setting.HostCorinne R. Young, MSN, FNP-C, FCCPDirector of APP and Clinical Services, Colorado Springs Pulmonary ConsultantsPresident, APAPP, Colorado Springs, COCorinne Young is a Nurse Practitioner began working in the area of pulmonary disease in California in 2005. Since 2011, she has worked in a private pulmonary practice in Colorado Springs, Colorado. Involvement and the representation of advanced practice providers in the pulmonary world has been an important priority for Corinne.  To that end,  Corinne is the Founder and President of the Association of Pulmonary Advanced Practice Providers.In addition to her work with APAPP, Corinne is currently one of ten NPs nationwide to become a Fellow of the American College of Chest Physicians. She works closely with the American College of Chest Physicians CHEST programs, and serves on the Interprofessional Team Network, Clinical Research Network, and on the Executive Programing Committee. Additionally, Corinne serves on the American Board of Internal Medicine Pulmonary Disease Board.This Podcast episode does not offer CME/CE Credit.Please visit http://naceonline.com to engage in more live and on demand CME/CE content.

How I Built This with Guy Raz
Electrifying aviation with Kyle Clark of BETA Technologies

How I Built This with Guy Raz

Play Episode Listen Later Aug 24, 2023 42:55


Not only is BETA Technologies completely changing the flying experience with its all-electric aircraft, it's upending the logistics of shipping altogether... This week on How I Built This Lab, founder and CEO Kyle Clark shares how BETA is building zero-emission, battery-powered aircraft, as well as a national charging network. Also, how the transition to electric will address aviation's emissions problem, and how a chance encounter with United Therapeutics founder Martine Rothblatt started it all. This episode was produced by Sam Paulson, with music by Ramtin Arablouei and Sam Paulson.Edited by John Isabella, with research help from Casey Herman. Our audio engineer was James Willetts.You can follow HIBT on Twitter & Instagram, and email us at hibt@id.wondery.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

ASCO Daily News
How Oncologists Are Confronting the Cancer Drug Shortage

ASCO Daily News

Play Episode Listen Later Aug 10, 2023 25:17


Drs. Vamsi Velcheti, Taofeek Owonikoko, and Janakiraman Subramanian discuss their experiences navigating the cancer drug shortage in the United States, the impact on patients and clinical trial enrollment, lessons learned, and proactive strategies to mitigate future crises. TRANSCRIPT  Dr. Vamsi Velcheti: Hello, I'm Dr. Vamsi Velcheti, your guest host for the ASCO Daily News Podcast today. I'm a professor of medicine and director of thoracic oncology at the Perlmutter Cancer Center at NYU Langone. On today's episode, we'll be discussing the impact of the shortage of cancer chemotherapy drugs across the United States. This has been affecting several thousands of patients with adult and pediatric cancers and hampering enrollment in clinical trials. Among the shortages are very commonly used drugs like cisplatin, carboplatin, methotrexate, and fludarabine. Some of these shortages have persisted since the time of the pandemic in 2020.   So today, to discuss this really troubling scenario, I have two outstanding colleagues, Dr. Janakiraman Subramanian, the director of thoracic oncology at Inova Schar Cancer Institute in Virginia, and Dr. Taofeek Owonikoko, a professor of medicine and the chief of the Division of Hematology and Oncology at the University of Pittsburgh Hillman Cancer Center in Pittsburgh.   Our full disclosures are available in the transcript of this episode, and disclosures relating to all episodes of the podcast are available at asco.org/DNpod.  So, a recent survey by the NCCN found that 90% of the nation's largest cancer centers have experienced a shortage in carboplatin, and 70% of the centers have reported a shortage in cisplatin. These are platinum-based chemotherapies we use frequently in patients with cancer, and these are often curative intent treatments for several cancers, and these are used in several tumor types, both solid tumors and hematologic malignancies. So, the scale of the problem is immense.   Dr. Owonikoko, I'd like to hear your take on this situation and how are you dealing with this at the UPMC Cancer Center.  Dr. Taofeek Owonikoko: Yeah, thank you, Dr. Velcheti, and happy to be part of this panel. As you rightly surmised, the chemotherapy drug shortage is what we've all experienced across the length and breadth of the United States. Our cancer center here in Pittsburgh is not an exception. We've had to be proactive as well as think outside the box to be able to manage the challenge. Just like every other cancer center across the country, maybe to varying degrees, we've had to look at patients in need of chemotherapy with these standard-of-care agents such as cisplatin or carboplatin, and to some degree docetaxel, during this past episode of drug shortage that we all went through. And while we did not have to, fortunately, cancel any patient treatment, we all went through it with bated breath; not sure of where the next batch of chemotherapy drugs will come through, but I would say in the past couple of weeks, we've actually seen some improvement in drug availability.   But before then, we've had to have contingency plans where, on a weekly basis, we review our patient list and the drug regimens that they're going to need, and must make sure that we have enough drug on hand for those patients. And in situations where we thought we might not have enough drug; we also had a plan to use alternative regimens. We were proactive in having guiding principles that are consistent with ASCO's recommendations in terms of quality care delivery for cancer patients. So, I'm sure that this is more or less the same approach adopted by other leading cancer centers across the country.   Dr. Vamsi Velcheti: Thank you, Dr. Owonikoko. And Dr. Subramanian, you're in a community setting, a large cancer center that serves a lot of patients in the state of Virginia. So, what is the scale of the problem at your institution and how are you handling it?   Dr. Janakiraman Subramanian: First of all, Dr. Velcheti, thanks for having me here on this panel. And as you rightly said, this is a significant problem, and it is across the country like Dr. Owonikoko said. And as medical oncologists, we are not always thinking of drug shortages. Our focus is on taking care of our patients. So, this is one more issue that we need to keep in mind now as we manage our patients with cancer. When this shortage started, the biggest problem, as you know, was when we became aware of this was primarily in cisplatin and we had some of our patients who were getting curative treatment and we had to make a decision - can they get cisplatin or can they get carboplatin. And one of the things we did was to have an ethics committee that will review each patient that is being planned to receive cisplatin-based chemotherapy and come to a decision on how best we can support them.   The template for some of this was based upon some of the triage mechanisms we used during COVID, as well as the ASCO guideline document for managing this chemotherapy shortage, which was one of the blueprints we used. And they have reviewed all cases, all patients that are being planned for cisplatin or carboplatin for that matter, and we come to a decision based on that. And we also have another committee that constantly monitors drug availability on a weekly basis and tries to forecast where the next problem would be as we take care of our patients.   And particularly as a lung cancer doctor, we've had situations where we had to use carboplatin instead of cisplatin and even we also have carboplatin shortage. And so, the committee usually approves two cycles at a time, but thankfully so far we have not had a situation where we could not offer our patients the chemotherapy treatment. But we are very carefully monitoring the situation, hoping that this will improve.   The other aspect of the shortage has been in 5FU. A lot of our GI colleagues; I treat esophageal cancer patients as well, where we've had to forego the bolus 5FU and have a 10% reduction on all 5FU infusions. And we've been using some of that dose reduction to ensure that we can have 5FU available for all our patients. And that's how we've been trying to manage this shortage situation here at Inova Schar.   Dr. Vamsi Velcheti: Dr. Subramanian and Dr. Owonikoko, we are oncologists, we are treating patients, and the toughest part really is telling a patient that we don't have access to certain drugs and we have to switch treatments to perhaps another treatment regimen that may be suboptimal. And it's always a very anxiety-provoking discussion, and especially for patients with metastatic cancer, they're already under a lot of stress and it's a really difficult conversation. How do you handle that, Dr. Owonikoko?  Dr. Taofeek Owonikoko: That's a conversation we all hope we don't have to have. And fortunately, with this current crisis, I've actually not had such misfortune of having to inform a patient that we don't have drugs to treat them or that we have to switch to something inferior. But conceptually, it's possible that could have happened and that would have been very difficult. But the one thing that we did, though, as part of our mitigation strategy was actually to inform the patient ahead of time because the way we handled this was to look at our inventory on a week-by-week basis. And if there are patients where we felt maybe they will be coming in towards the end of the week and we may not have enough drugs for them, to let them know the possibility exists that we might have to switch them to something different. While we did not have to do that for any patient, yes, there are patients that we had to give that heads up to, to say, “We're having this shortage. We're doing everything we can to make sure it's available. But just in case it's not available…” I think what is most important for most patients is to be aware of that decision ahead of time, to be able to process it, and to be transparent.   The other challenge that we face was, if you have to choose between patients, what should be your guiding principles as to who gets the drug and who doesn't get it? I think it's very easy for all of us to say, “Oh, if it's curative intent, we do it. If it's not curative intent, we don't do it.” It's a little more complicated than that because if we put the equity hat on, curative intent doesn't actually mean that that life is more valuable than somebody who cannot be cured. And this is where really, I think having people with expertise in ethics of care delivery and disaster management will be very important for us to proactively anticipate that, should this become a recurrent problem in the future that we actually have a well-vetted approach, just like we did during COVID where you have to ration resources that we have those people with expertise to help us as oncologists because not all of us, at least personally I can speak for myself, that is not my area of expertise and comfort.  Dr. Vamsi Velcheti: Excellent points. Dr. Subramanian, anything to add?  Dr. Janakiraman Subramanian: Oh, absolutely. I echo what Dr. Owonikoko said. These are conversations that we would like to hopefully never have with our patients. But this is a crisis that we are facing now. And personally, I can tell you two situations where we ran into this problem. But overall, though, we never had to stop a treatment or cancel a treatment for our patient. In the first situation, we had a young man with a rare germ cell tumor in the hospital for whom cisplatin was key. He was already in the ICU and sometimes the treatment start dates are not perfect, unlike what we do in the outpatient setting, depending on how well he's doing or the treatment start dates might move by a day or so. So we basically had to hold a certain dose of cisplatin for him.   This brings the next question, which is how do we decide who gets cisplatin versus who can go for an alternative option? And I think Dr. Owonikoko made a great point where, just because it is a curative disease does not mean their life is more valuable. This is where I think trying to make that decision at an individual level, as an individual treating physician can be extremely hard. And that's why at our institution we have this ethics committee where we have oncologists, pharmacists, and ethicists that review these chemotherapy orders, particularly for cisplatin, and try to use some guiding principles that we learned from COVID as well as ASCO's guidance to decide how we assign our resources. That's one option, one way we have done it.    And then in another situation that was faced by one of my GI oncology colleagues was a patient that was originally planned to go on a clinical trial where the chemotherapy backbone was FOLFOX and because we had the 5FU shortage, we could not offer that patient clinical trial enrollment. And that was a tough conversation where they had to tell them that they could not go on a clinical trial that they were looking forward to. And this then brings the next question, which is by foregoing the bolus 5FU and by the 10% reduction in the infusional 5FU, are we providing them inferior treatment? And it's a conversation that's had at a very individual level. I don't envy my colleague who had to have that conversation. It's a challenge and we try to do our best to communicate to our patients that we are trying to provide care without trying to compromise the effectiveness of treatment for them.  Dr. Vamsi Velcheti: Thank you so much both of you. And we had the same issues here at NYU in New York City as well. It appears, you know, the degree of shortage and the drugs that are in shortage has been somewhat different at different locations across the United States. But the theme has been that we are having to ration treatments for our patients. And of course, there are some tumor types where there's really no adequate substitution, for example, GU cancers. I mean, you can't really not give them cisplatin. A lot of these are situations which have curative intent and young patients. So, it's really troubling.   And I think one of the things that really came out of this is there's been a lot of push from professional societies that actually ASCO has been spearheading and some intense discussions with CMS and legislators to kind of provide more long-term fix for these things. And I think all of us have to be more engaged in those discussions with our professional societies like ASCO to kind of help promote awareness. So if you kind of think about it, these drugs are not that expensive. These are generic drugs that we've all been using for such a long time. And the fact that we can't provide these drugs for various reasons is kind of really concerning. We spend so much money on research and more expensive drugs and not being able to manufacture these drugs within the country and kind of having to rely on complex supply chains is troubling, and I hope the situation improves very soon.    So, I know both of you are at large cancer centers that enroll patients on clinical trials. Of course, these drugs, especially carboplatin, for lung cancer, especially, are like core treatments that are used in managing cancer patients with lung cancer. So how is this affecting your clinical trial accrual? Are you prioritizing patients on clinical trials for these drugs? Have you had to make any decisions to hold clinical trial accrual for certain trials? Kind of curious to hear.  Dr. Taofeek Owonikoko: Yeah, so I can maybe weigh in a little bit on that in terms of what we've had to do for patients receiving treatment as standard of care versus those going on clinical trials. As we all recognize that when a patient goes on a clinical trial, even if they are going to receive a standard-of-care regimen as part of that trial, it still has to be administered in line with the protocol. So, during the extreme period of shortage anxiety, we actually had consideration for perhaps not putting patients on trial if we're not sure that they will be able to continue to receive the protocol-mandated treatment, whether it's a control intervention or the experimental intervention.   The good thing to come out of this is at least here at UPMC, we actually did not have any instance where we had to deny a patient clinical trial participation. But there were anxious periods when we already had patients enrolled and they were scheduled to receive a platinum-containing regimen and we were not sure whether or not we were going to have adequate supply of the drug for them while on trial. I think this really raises an important consideration going forward as we come out of this current shortage. I don't by any stretch of the imagination assume that this is going to be the last one we experience, but I think the lessons learned here, we have to also carry that forward both in the design of the trial as well as in the regulatory environment surrounding clinical trial conduct, to say, should another incidence of drug shortage are to happen, how do we actually operationalize that with respect to patients on trial, whether starting or already on trial?   I think it's much more challenging when the patient is already on the trial, they've already started. It's less challenging if you just have to make a decision about somebody starting newly on the trial. But equally important is that by not allowing new patients to go on trial is denying something that potentially could be of benefit to them, albeit it is still a trial, it's not an established treatment option yet.  Dr. Janakiraman Subramanian : I completely agree with Dr. Owonikoko. Those were very key points and issues that we face as well. In terms of my patients with lung cancer, we haven't had a problem in getting them on clinical trials. Even though we have had carboplatin shortage patients who are already on treatment, they were able to get the carboplatin. For new patients, we were still able to provide them carboplatin as well. The biggest problem for clinical trials has been primarily with my GI colleagues who have to use 5FU. And there, as I said before, we are unable to give bolus 5FU and there is a 10% reduction of the infusional 5FU. So, we can't have any of these patients go on clinical trials.    And as a result, anything that has to do with 5FU has come to a screeching halt in terms of clinical trials for our patients. And I think I echo the point of Dr. Owonikoko that by no means this is the last drug shortage we're going to be dealing with and we are here today discussing this, also because this shortage has not ended. It's been ongoing. It's one of the longest drug shortages in my memory as a medical oncologist, and that's concerning. We still see that there is some improvement, but we haven't gotten past it yet.     And therefore, as we develop clinical trials and we need to have methods to address drug shortages and how we manage patient enrollment as well as how do we manage existing patients who are already on a clinical trial and, if possible, what might be their options in that situation. We may not have all the answers, but it is definitely an issue that we need to think about in the future as we develop and implement newer clinical trials for our patients.  Dr. Vamsi Velcheti: I completely agree and great points, both of you. And we've had the same issues with clinical trials at NYU Langone as well due to the shortage. It's been a challenge, and I think this is a problem that's so complex because of supply chain issues and the way the drugs are priced and incentives for manufacturing these drugs in the United States are not lucrative enough to actually onshore a lot of the production of these drugs.   I think at the end of the day, I think we have to come up with some creative, innovative, reimbursement structures for these generic chemotherapy drugs. I think this would require a very complex economic solution that perhaps ASCO and other organizations should kind of really foster an environment of innovation to kind of help facilitate onshoring some of the manufacturing of these key drugs within the United States. I think ASCO is already trying to do that, trying to collaborate with all the stakeholders to kind of address this problem is very critical, and I think all of us have to be engaged in some of the advocacy efforts that are ongoing to kind of address these drug shortages. And this is not a short-term problem.  So, Dr. Owonikoko and Dr. Subramanian, any final thoughts before we wrap up the podcast today?  Dr. Janakiraman Subramanian: So, Vamsi, you mentioned the whole complex supply chain and the fact that we rely primarily on overseas manufacturers to get these drugs that are off-patent but still a key backbone of our cancer treatment. I think those are all key issues that policymakers and leaders in the field have to keep in mind. As an institution at Inova, one of the key mechanisms that have helped us to sort of stay ahead of the shortage was to have this inventory management team that monitors the inventory out there. And in fact, the inventory management team does have access to what the inventory is in some of their main suppliers in terms of the drugs. And they also have an idea of how many patients are going through treatment, what is the weekly usage of a specific drug like carboplatin. And they try to forecast what is coming down the road and try to prepare for it.   And as we try to look for solutions, maybe a forecasting mechanism in a larger scale like either spearheaded by ASCO or by policymakers level that can, for the overall country, try to see where some of the inventory is for some of these critical drugs and try to prepare for it ahead of time, rather than wait till we hit the shortage and then try to find alternative suppliers to get the drug, which obviously doesn't happen quick enough. It takes months or even longer to catch up and get the inventory back to the level where we can comfortably take care of our patients.  I think that is something we should be advocating for that as well as the professional societies should take a handle on that and see if they can support something like that as well as letting the institutions know ahead of time what's coming might be very helpful.  Dr. Vamsi Velcheti: Yeah, very good point, Janakiraman, and I think that's a key takeaway here. I think we have to learn from other industries and try to– I mean this is not unique to healthcare by any means. I mean these chronic shortages due to supply chain issues, inventory management, there might be some learnings from other industries here that we probably should also focus on inventory management and improve supply chain logistics.   Dr. Owonikoko, any closing thoughts?   Dr. Taofeek Owonikoko: Yeah, I agree as well with all the points made by Dr. Subramanian and yourself. This is a chronic problem that requires a long-term strategy. I think it's both an economic problem as well as a regulatory problem. As we all know, part of the reason why we went through this current crisis is the regulatory decision by the FDA regarding safety of one of the manufacturers. So being proactive in terms of how these audits are conducted and giving people lead time I think will help avoid similar situations in the future.    It's an economic problem. There's a reason why a lot of the big pharma companies are not producing these drugs. And if the cost of production is such that the amount of money you get paid is enough to cover your price, I think there is an economic issue there to be addressed. That is unfortunately not within the scope of what any one of us can do individually, but as advocates in terms of the structure of incentivizing new drug versus old drug, some of these newer drugs are quite expensive, but oftentimes they are used along with standard drugs that are not as expensive. So, where do we strike that balance where we do not stifle innovation but at the same time, we don't create a perverse incentive system where everybody just wants to come up with the newest, most expensive drug and nobody is interested in really producing the backbone chemotherapy and other agents that will make those new drugs work well.   So, I think we have to pay attention. We have to advocate for our patients through our different institutions and organizations, and I hope that society as a whole that we've learned a lot of lessons from this crisis and that will help us craft some long-term strategies.   Dr. Vamsi Velcheti: Thank you both Dr. Owonikoko and Dr. Subramanian for your time today to speak with me and our listeners and for sharing your insights with us on the ASCO Daily News podcast.   Dr. Taofeek Owonikoko: Thank you.   Dr. Janakiraman Subramanian: Thank you.  Dr. Vamsi Velcheti: And thank you to our listeners for your time today. If you value the insights that you hear on ASCO Daily News Podcast, please take a moment to rate, review and subscribe wherever you get your podcast. Thank you so much.  Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.  ASCO Resources Related to Drug Shortages are available here.     Follow today's speakers:    Dr. Vamsidhar Velcheti    @VamsiVelcheti    Dr. Janakiraman Subramanian  @RamSubraMD  Dr. Taofeek Owonikoko  @teekayowo    Follow ASCO on social media:     @ASCO on X (formerly Twitter)    ASCO on Facebook    ASCO on LinkedIn      Disclosures:     Dr. Vamsidhar Velcheti:     Honoraria: ITeos Therapeutics    Consulting or Advisory Role: Bristol-Myers Squibb, Merck, Foundation Medicine, AstraZeneca/MedImmune, Novartis, Lilly, EMD Serono, GSK, Amgen, Elevation Oncology, Taiho Oncology, Merus    Research Funding (Inst.): Genentech, Trovagene, Eisai, OncoPlex Diagnostics, Alkermes, NantOmics, Genoptix, Altor BioScience, Merck, Bristol-Myers Squibb, Atreca, Heat Biologics, Leap Therapeutics, RSIP Vision, GlaxoSmithKline      Dr. Janakiraman Subramanian:  Consulting or Advisory Role: AstraZeneca, Boehringer Ingelheim, Pfizer, Novartis, Daichi, G1 Therapeutics, Jazz Pharmaceuticals, Janssen Oncology, Lilly, Blueprint Medicines, Axcess, BeiGene, Cardinal Health, Takeda, OncoCyte  Speakers' Bureau: AstraZeneca, Boehringer Ingelheim, G1 Therapeutics, Jazz Pharmaceuticals, Janssen Oncology  Research Funding (Inst.): G1 Therapeutics, Tesaro/GSK, Novartis, Genentech, Novocure, Merck   Dr. Taofeek Owonikoko:  Stocks and Other Ownership Interests: Cambium Oncology, GenCart, Coherus Biosciences  Consulting or Advisory Role: Novartis, Celgene, Abbvie, Eisai, GI Therapeutics, Takeda, Bristol-Myers Squibb, MedImmune, BerGenBio, Lilly, Amgen, AstraZeneca, PharmaMar, Boehringer Ingelheim, EMD Serono, Xcovery, Bayer, Merck, Jazz Pharmaceuticals, Zentalis, Wells Fargo, Ipsen, Roche/Genentech, Janssen, Exelixis, BeiGene, Triptych Health Partners, Daichi, Coherus Biosciences  Speakers Bureau: Abbvie  Research Funding (Inst.): Novartis, Astellas Pharma, Bayer, Regeneron, AstraZenece/MedImmune, Abbvie, G1Therapeutics, Bristol-Myers Squibb, United Therapeutics, Amgen, Loxo/Lilly, Fujifilm, Pfizer, Aeglea Biotherapeutics, Incyte, Merck, Oncorus, Ispen, GlaxoSmithKline, Calithera Biosciences, Eisai, WindMIL, Turning Point Therapeutics, Roche/Genentech, Mersana, Meryx, Boehringer Ingelheim  Patents, Royalties, Other Intellectual Property (Inst.):   Overcoming Acquired Resistance to Chemotherapy Treatments Through Suppression of STAT3  Selective Chemotherapy Treatments and Diagnostic Methods Related Thereto  DR4 Modulation and Its Implications in EGFR-Target Cancer Therapy Ref: 18089 PROV (CSP) United States Patent Application No. 62/670,210 June 26, 2018 (Co-Inventor)  Soluble FAS ligand as a biomarker of recurrence in thyroid cancer; provisional patent 61/727,519 (Inventor)  Other Relationship: Roche/Genentech, EMD Serono, Novartis  Uncompensated Relationships: Reflexion Medical           

Cold Call
How Martine Rothblatt Started a Company to Save Her Daughter

Cold Call

Play Episode Listen Later Apr 26, 2023 20:38


When serial entrepreneur Martine Rothblatt (founder of Sirius XM) received her seven-year-old daughter's diagnosis of Pulmonary Arterial Hypertension (PAH), she created United Therapeutics and developed a drug to save her life. When her daughter later needed a lung transplant, Rothblatt decided to take what she saw as the logical next step: manufacturing organs for transplantation. Rothblatt's entrepreneurial career exemplifies a larger debate around the role of the firm in creating solutions for society's problems. If companies are uniquely good at innovating, what voice should society have in governing the new technologies that firms create?

LifeSci Beat
Alex Sapir, Former CEO of ReViral Ltd. and Dova Pharmaceuticals, on Advancing Pipeline Candidates and Financing Biotech Companies

LifeSci Beat

Play Episode Listen Later Apr 3, 2023 36:41


In the eighth episode of this season, we chatted with Alex Sapir about his various experiences leading life sciences companies through commercial launches and key funding milestones. We spoke about his career beginnings at GSK, ZS Associates, and United Therapeutics. Additionally, we covered his CEO tenures at Dova Pharmaceuticals and ReViral Ltd - both of which were acquired.

Design Nerds Anonymous
How to Amplify Your Impact Demystifying Sustainability

Design Nerds Anonymous

Play Episode Listen Later Oct 27, 2022 33:08


In this episode, ThinkLab interviews David Schwarz, founding partner at HUSH, about the design firm's innovative approach to sustainability, and Rebecca Best, head of sustainability at Material Bank, on how the world's largest material aggregator is helping designers make more sustainable decisions.   Our first guest is David Schwarz, founding partner at HUSH, an experience design firm. Schwarz shares forward-thinking ways HUSH is leveraging design to connect the occupants of a space to how their own daily microdecisions affect the sustainability of a building. To that end, he describes an award-winning project, designed in partnership with United Therapeutics, which sought to make a building's cutting-edge engineering visible and able to be appreciated by workers and visitors.   Our next guest, Rebecca Best, is vice president of sustainability at Material Bank. She explains that sustainability is so complex — requiring designers to balance climate, human health, and social justice concerns — that it can't really be simplified. She counsels design firms to focus on making the decision-making process more efficient and shares strategies for how to empower clients.     In this episode:  [4:12] David details the two-part mission behind HUSH's memorable project with United Therapeutics.  [15:55] “We don't want to require that our clients become sustainability and energy experts.”  [24:17] Rebecca describes the most pressing sustainability concerns by sector.  [28:56] Rebecca speaks to the importance of celebrating small wins as a way to encourage collective action.  Connect with our interviewees on LinkedIn:  David Schwarz   Rebecca Best    This season of Design Nerds Anonymous is brought to you by Mannington Commercial, theMART, and NeoCon, companies doing big things to move the design industry forward.    Download our leading-edge playbook: 5 Personas and 50 Ways to Design Their Phygital Journey.    Design Nerds Anonymous is a proud member of the SURROUND Podcast Network. Discover more shows from SURROUND at surroundpodcasts.com. This episode of Design Nerds Anonymous was produced and edited by SANDOW Design Group, with music from Blue Dot Sessions. Special thanks to the podcast production team: Hannah Viti, Wize Grazette, and Samantha Sager. 

Freely Filtered, a NephJC Podcast
Freely Filtered 044: Pigs on the Wing: Xenotransplantation

Freely Filtered, a NephJC Podcast

Play Episode Listen Later Apr 11, 2022 63:12 Very Popular


The Filtrate:Joel TopfJoshua WaitzmanNayan AroraJordy CohenSpecial Guest:Josh Mezrich Editor:Nayan AroraShow Notes:When Death Becomes Life: Notes from a Transplant Surgeon. AmazonAm J Transplant 2022 Jan 20. doi: 10.1111/ajt.16930. PMID: 35049121Coverage on NephJCFirst transplant of a pig into a human. NYU transplant. Keith Reemtsma's experience with chimpanzees transplantation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1408776/?page=1 Infection of human cells by an endogenous retrovirus of pigsUnited Therapeutics page on xenokidney.Article by Starzl on the early days of kidney transplant, including David Humes experiment grafting kidneys to the arms and grafts of patients. The Early Days of TransplantationPatient in Groundbreaking Heart Transplant DiesHeterotopic heart transplantation: where do we stand?Denton Cooley and the first artificial heart transplantFor the First Time in North America, a Woman Gives Birth After Uterus Transplant From a Deceased DonorBlacksburg company raised genetically modified pig for first heart transplant into humanChristiaan Barnard and the first human-to-human heart transplantMaking The Impossible Possible: A Conversation With Martine Rothblatt. The founder of United Therapeutics and SiriusXMPaige Porrett, M.D., Ph.D. first authorJayme Locke, M.D., MPH senior authorLouise Penny author pageThe Four QuestionsChutzpod!Joshua Malina, not the new cantor at Temple Israel.Primitive Technology YouTube Channel

AKTIONÄR TV-Expertensendung
Opening Bell: Bitcoin, Coinbase, Peloton, Amazon, Nike, Apple, Meta, United Therapeutics, Alibaba

AKTIONÄR TV-Expertensendung

Play Episode Listen Later Feb 7, 2022 20:11


Vor dem Wochenende trat der amerikanische Leitindex auf der Stelle. Der Dow Jones ging beinahe unverändert aus dem Handel. Der S&Phingegen legte um 0,5 Prozent zu.

Trans Resister Radio
Revivicor My Soul, AoT#341

Trans Resister Radio

Play Episode Listen Later Jan 17, 2022 58:46


Anyone who is sick of it all, come listen to this podcast and join Aaron in saying FTW.  Topics include: appearances on other shows, Patreon, transhumanist agenda, nothing makes sense, average person's viewpoint, charade of politics, no winning Covid situation, Trump supporters will follow him to any end, insurrection, coup, January 6, constantly changing story, Biden a total lame duck, 2024 election, crime, Robocop, Detroit, Martine Rothblatt's Pig Heart Revival, genetic engineering, United Therapeutics, Revivicor, Soylent Green, Matrix Resurrections, Keanu Reeves, Alex Jones

AKTIONÄR TV-Expertensendung
Moderna, Delta Airlines, Carnival, Booking, Enphase, United Therapeutics, Shopify - Opening Bell

AKTIONÄR TV-Expertensendung

Play Episode Listen Later Jan 13, 2022 12:05


Die Anleger an der Wall Street präsentierten sich gestern weitestgehend zurückhaltend. Der Anstieg der Inflation auf sieben Prozent bremste die gute Laune. Der Dow Jones ging mit einem kleinen Plus von 0,1 Prozent aus dem Handel.

AKTIONÄR TV-Expertensendung
Moderna, Delta Airlines, Carnival, Booking, Enphase, United Therapeutics, Shopify - Opening Bell

AKTIONÄR TV-Expertensendung

Play Episode Listen Later Jan 13, 2022 12:05


Die Anleger an der Wall Street präsentierten sich gestern weitestgehend zurückhaltend. Der Anstieg der Inflation auf sieben Prozent bremste die gute Laune. Der Dow Jones ging mit einem kleinen Plus von 0,1 Prozent aus dem Handel.

AKTIONÄR TV-Expertensendung
WeWork, Snap, Facebook, Zoom Video, Nvidia, Alibaba, Intel, United Therapeutics - Opening Bell

AKTIONÄR TV-Expertensendung

Play Episode Listen Later Oct 22, 2021 19:44


Der S&Pstieg gestern auf ein neues Allzeithoch. Am Ende des Tages legte er 0,3 Prozent zu. Dem Dow Jones gelang es nicht auf ein Rekordhoch zu steigen.

Hurdle
174. Devon Still, Former NFL Player & Advocate for Childhood Cancer Awareness

Hurdle

Play Episode Listen Later Aug 30, 2021 30:06


Wow. I probably say that word at least 15 times in today's episode with Devon Still, former NFL player, author, speaker, and advocate for childhood cancer awareness. In 2014, Devon's world was turned upside down when his then 4-year-old daughter Leah was diagnosed with stage 4 neuroblastoma in 2014 and given a 50-50 chance to survive. In today's episode, he talks me through all of it — from feeling powerless at her bedside to how he learned to embrace vulnerability. A huge thank you to United Therapeutics for setting up this conversation, as Devon recently partnered with them on a new "Braving NeuroBLASToma" campaign. SOCIAL @stillinthegame @emilyabbate @hurdlepodcast CHECK OUT THE NEW HURDLE WEBSITE! JOIN: THE *Secret* FACEBOOK GROUP LEAVE ME A VOICE MESSAGE! Whether you just want to say hi or have a question you want to ask, I'd love to hear from you! Bonus: Your listener question could be answered in an upcoming episode of the show! P.S. No topics are off limits. --- Send in a voice message: https://anchor.fm/hurdle/message

PF News & Perspectives
FDA Accepts Priority Review Request for Tyvaso DPI

PF News & Perspectives

Play Episode Listen Later Jun 24, 2021 5:52


Pulmonary Fibrosis News Columnist and Forum Moderator Charlene Marshall reads an article summarizing the review request for Tyvaso DPI to be used in patients with pulmonary arterial hypertension (PH) and PH associated with interstitial lung diseases (ILDs), including those with IPF. Tyvaso is currently approved by the Food and Drug Administration in the US, however, the examination of how an inhaled form of Tyvaso (Tyvaso DPI) might better assist patients with PH and PH-ILDs is currently under way by United Therapeutics. If you have ILD-induced pulmonary hypertension, have you ever spoken to your doctor about Tyvaso? Are you interested in learning more about Pulmonary Fibrosis? If so, please visit: https://pulmonaryfibrosisnews.com

The Unspeakable Podcast
Buck Angel Bucks the Trend: An Old-School Transexual on the New Transgender Movement

The Unspeakable Podcast

Play Episode Listen Later May 30, 2021 80:34


Buck Angel is an entrepreneur and a speaker and educator about transgender issues, particularly issues related to trans healthcare. Now in his late 50s, he transitioned from female to male in his late 20s and has more recently became a controversial figure in certain corners of the trans community. He talked with Meghan about why he's so controversial, what it's been like to spend decades on masculinizing hormone therapy, and why he's worried about the number of clinicians now prescribing such therapies to young people after minimal psychological counseling.    For the record: at one point in the interview Buck mistakenly referred to the biotech entrepreneur Martine Rothblatt as Martine Rathbaum. He also suggested that Rothblatt, who is the founder of the biotech company United Therapeutics, is among the billionaire class. As of March 2021, United Therapeutics was reportedly worth $7.1 billion. Rothblatt herself, according to Forbes, is worth $390 million.     Guest Bio: Buck Angel is an entrepreneur and educator in the area of trans male healthcare and sexual wellness. He has also been a groundbreaking figure in the porn industry, which you can learn about on his website and also in a documentary about his life, Mr. Angel, which was released in 2013 and premiered at the South by Southwest Film Festival. 

Build The Future
Derek Morris of United Therapeutics — The Future of Transplants, Organs, and Art

Build The Future

Play Episode Listen Later May 18, 2021 39:42


In this episode of Build the Future, we talk with Derek Morris, a Director of Engineering at United Therapeutics. At United Therapeutics they’re on a mission to develop novel, life-extending technologies for patients battling with lung disease. In addition to developing medicine and transplant technology, they’re also leading cutting-edge research on organ manufacturing (3D printing of organs) which Derek leads.This episode should be reclassified as a schedule 1 stimulant — full of energy and optimism, we go off track on a wild tangent adventure covering art, media, inputs, the future, the World's Fair, and of course the incredible work being done at UT to print 3D organs.To listen to more episodes and to stay connected, follow along athttps://www.buildthefuturepodcast.com/https://twitter.com/camwieseDon’t forget to leave a review and subscribe.Have a great week and until next time, go build!

ASCO Daily News
Dr. Taofeek Owonikoko Previews a Dynamic #ASCO21 Education Program Focused on Equity

ASCO Daily News

Play Episode Listen Later May 6, 2021 12:11


In this episode, Dr. Taofeek Owonikoko, lung cancer specialist at the Winship Cancer Institute at Emory University and chair of the 2021 ASCO Annual Meeting Education Program, discusses the diverse ways that cancer care equity will be featured during #ASCO21.   Transcript ASCO Daily News: Welcome to the ASCO Daily News podcast. I'm Geraldine Carroll, a reporter for the ASCO Daily News. My guest today is Dr. Taofeek Owonikoko, a lung cancer specialist at the Winship Cancer Institute at Emory University. Dr. Owonikoko serves as the chair of the education program of the 2021 ASCO Annual Meeting. And he's here to tell us about the diverse sessions that will be featured this year. Dr. Owonikoko reports no conflicts of interest relating to our discussion today. His full disclosures and those relating to old episodes of the podcast are available at asco.org/podcast. Dr. Owonikoko, it's great to have you on the podcast today. Dr. Taofeek Owonikoko: Thank you. Glad to be here. ASCO Daily News: Health equity is the major theme of this year's Annual Meeting. And as you know, ASCO's President, Dr. Lori Pierce, has been focusing on patient care equity during her term. Can you tell us about how the concept of cancer care equity has been incorporated into the education program this year? Dr. Taofeek Owonikoko: Thank you very much. I actually want to use this opportunity for us to thank all the ASCO volunteers, who spent countless hours putting together a very educational program for the Annual Meeting. It's very difficult for me to come out and say [that] this is the best session to go to. I think all of the sessions are very important and educational. The challenges that we've faced with COVID-19 that is making this a virtual meeting, actually, I think is an opportunity for people to be able to participate in all these sessions. Having said that, there are some sessions that we intentionally placed within the Education Program based on how important we felt these topics were to our patients, to their caregivers, family members, and also to ASCO members. We want sessions that focus on various aspects of health equity from individual patient interaction with their providers, to patient experience within the larger context of how health care systems are built, and how we deliver care. Some of the sessions that I really encourage members to listen to and participate in will be--there is a session that is going to bring diverse viewpoints from across the world, not just in the U.S. We want to see how oncologists practice in a limited resource setting, how they go about taking care of patients, and how they are able to use the challenges that they face as a stepping stone to bring the best care forward for that patient. So we have this session where we're going to have a speaker from Uganda in Africa. We have another speaker from Pakistan representing the Asian viewpoint. We are going to have a speaker who will speak to delivering care to the inner city population here in the U.S. And that session will also have a speaker that will discuss how we take care of our patients within the Native American community here in the U.S. So you're going to see these diverse viewpoints that we feel will shed light on the important point that Dr. Pierce has been trying to make with the presidential theme, that we need to focus on every patient, everywhere in terms of equitable care delivery. ASCO Daily News: Intersectionality in cancer care is a topic that has been getting more attention over the past year. How will this issue be addressed during the Education Program? Dr. Taofeek Owonikoko: We've talked about determinants of health outcomes for patients. How we look at all of these issues in isolation, whether it's gender, sexual orientation, race or ethnic background, rural versus urban, big city versus small towns, and different regions of the world. There's actually now this emerging consensus that a lot of these factors actually do not stand alone. There is an intersection of where someone lives and what type of access they have to health care--where someone lives and what type of care providers, someone's gender, and their socioeconomic status influencing the outcomes of care that they get. So this session on intersectionality, I think will really bring this to the forefront of our discussion about how to address health inequities--that we don't want to focus on one issue at a time. All these issues are important and they are interrelated. I think this type of session will help all of us to understand that there's a lot going on that determines the outcome for patients, especially for patients with cancer. One additional session I want to highlight, which is also very important to the presidential theme is the session on viruses and cancer. While there is this pandemic with the COVID-19 virus that we are very aware of, what we also did not want to lose sight of is the fact that viruses are etiology for cancer. This has been a topic that we've been struggling with for decades. And now that everyone is paying attention to the COVID-19 virus and development of a vaccine to prevent the infection or make the severity less for those who eventually get infected, I think we also need to bring that focus back to what viruses have done as etiology for different types of cancer--from either neck cancer to cervical cancer to liver cancer. And bringing this session together which speaks to how viral infection could be a key driver of the geographical differences in incidence of cancer around the world, I think will be very important for ASCO members and the general audience attending the meeting. ASCO Daily News: Absolutely, well you spoke about the pandemic and of course today health care inequality is more relevant than ever. As you say, the pandemic has disproportionately affected people of color, so clearly changes must occur if the oncology field if it is to make strides in improving outcomes for patients of color, increasing representation in clinical trials, for example, improving access to precision medicine and more. So what do you hope that people will take away from this meeting, that will stay with them in the months and years ahead? Dr. Taofeek Owonikoko: Yeah, I'm very hopeful that at the end of the Annual Meeting, with all the offerings we have in terms of educational sessions and topical issues that we want to address and some of them very provocative, we will learn that we have to be honest and open. Some of these issues are not easy to discuss, but we have to confront them if we are going to get past that, and not just brush them aside but actually have genuine discussion and be open about what the challenges are. I think that, when we look at the impact of cancer care delivery and the disparate outcomes that we see across different minority communities, including people of color, this doesn't just start from where you're delivering care, it also has to do with how we actually develop treatments that are given to patients. And nothing brings that to the surface [more] than what we've observed in terms of participation of people of color in cancer clinical trials. I know that this is a vaccine issue it's not something that I just started today, but we have to then become more systematic as to how we address it. If we are going to develop drugs that are going to be applicable to all populations, we have to be intentional in making sure that we have equitable and fair representation of all people, and that the treatment would be applicable too, so that we can start learning right from the beginning of the earliest stages of drug development. Whether there are unique differences in the way these drugs work, whether there are cultural influences that would determine whether or not the way we want to administer the drug is going to have any impact. And I want to use this to highlight one session that we have put together that's going to talk about minority patient enrollment in clinical trials. This session is not about the problem. We all recognize what the problem is. This is actually a session that is meant to show potential solutions, where we invited experienced investigators in this area to talk about gaps in how we conduct clinical trials, and what can be done to improve that process. They will talk about communications and blind-spots that we as oncologists and investigators may not even be aware of when we talk about clinical trials and we want someone to participate--what are the things that we can do to make sure that we convey the information about this study in a culturally appropriate manner, so that our own attitude of presenting the trial does not alienate and discourage participation from people of color and other minority groups? And then, there will be a talk about a real world experience of a large trial where key factors led to success in recruiting people of color on a large randomized phase III trial of prostate cancer that will be shown and shared with the audience. And people can take this back home to their individual practices and countries to see whether or not some of these strategies will also be applicable to them to help get around this problem of poor enrollment of minority patients in cancer clinical trials. ASCO Daily News: Thank you, Dr. Owonikoko, for highlighting some of these important issues on minority enrollment in cancer clinical trials, intersectionality, and cancer care, the management of DNA virus associated cancers, and the always popular ASCO voices session, which this year will use the power of the narrative to advocate for equity in cancer care. Dr. Owonikoko, thank you again for taking the time to speak with me today. Dr. Taofeek Owonikoko: Thank you. ASCO Daily News: And thank you to our listeners for joining us as well. If you're enjoying the content on the podcast, please take a moment to rate, and review us wherever you get your podcasts.   Disclosures: Dr. Taofeek Owonikoko Stock and Other Ownership Interests: Cambium Oncology Consulting or Advisory Role: Novartis, Celgene, Abbvie, Eisai, G1 Therapeutics, Takeda, Bristol-Myers Squibb, MedImmune, BerGenBio, Lilly, Amgen, AstraZeneca, PharmaMar, Boehringer Ingelheim, EMD Serono, Xcovery, Bayer, Merck, Jazz Pharmaceuticals, Zentalis, Wells Fargo, Ipsen, Eisai, Roche/Genentech, Janssen Speakers' Bureau: Abbvie Research Funding (Institution): Novartis, Astellas Pharma, Bayer, Regeneron, AstraZeneca/MedImmune, Abbvie, G1 Therapeutics, Bristol-Myers Squibb, Corvus Pharmaceuticals, United Therapeutics, Amgen, Loxo/Lilly, Fujifilm, Pfizer, Aeglea Biotherapeutics, Incyte, Merck, Oncorus, Ipsen, GlaxoSmithKline, Calithera Biosciences, Eisai, WindMIL, Turning Point Therapeutics, Roche/Genentech, Mersana, Meryx, Boehringer Ingelheim Patents, Royalties, Other Intellectual Property (Institution): OVERCOMING ACQUIRED RESISTANCE TO CHEMOTHERAPY TREATMENTS THROUGH SUPPRESSION OF STAT3, SELECTIVE CHEMOTHERAPY TREATMENTS AND DIAGNOSTIC METHODS RELATED THERETO, DR4 Modulation and its Implications in EGFR-Target Cancer Therapy Ref:18089 PROV (CSP) United States Patent Application No. 62/670,210 June 26, 2018 (Co-Inventor), Soluble FAS ligand as a biomarker of recurrence in thyroid cancer; provisional patent 61/727,519 (Inventor) Other Relationship: Roche/Genentech, EMD Serono Uncompensated Relationships: Reflexion Medical Disclaimer: The purpose of this podcast, is to educate and to inform. This is not a substitute for professional medical care, and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.

The Clinical Research Circle
United Therapeutics UTHR Stock and A Mini CAR T Lesson

The Clinical Research Circle

Play Episode Listen Later Mar 5, 2021


Dan, Chris, Monica, and Dr Al discuss UTHR and CAR T Therapy

Health Professional Radio - Podcast 454422
United Therapeutics - TYVASO® (treprostinil) INCREASE Study Data

Health Professional Radio - Podcast 454422

Play Episode Listen Later Feb 21, 2021 12:01


Dr. Leigh Peterson, Ph.D., Vice President of Product Development at United Therapeutics discusses data published in the "New England Journal of Medicine" (Jan 2021) on the INCREASE study evaluating Tyvaso in pulmonary hypertension associated with interstitial lung disease (PH-ILD). The INCREASE study is the first to demonstrate a clear benefit in patients with PH-ILD, a life-threatening disease with no currently FDA-approved treatments. She talks about what's next for Tyvaso as they look to achieve FDA approval. Leigh Peterson: In her role as Vice President, Product Development, Dr. Peterson is responsible for coordinating and managing all aspects of preclinical and clinical development of United Therapeutics’ products. Dr. Peterson joined United Therapeutics in 2008 as a Senior Clinical Research Scientist and was promoted to her current role as Vice President of Product Development in March 2017. Dr. Peterson received a BS in Biochemistry from the University of Wyoming, a PhD in Molecular Biology - Human Genetics from the University of Utah, and conducted postdoctoral research in Developmental Neurobiology at The Rockefeller University.

Hand Curated Episodes for learning by OwlTail
The Tony Robbins Podcast: The Wonder Woman who might save your life | Meet Martine Rothblatt, Sirius XM co-founder who now creates life-saving technologies

Hand Curated Episodes for learning by OwlTail

Play Episode Listen Later Dec 24, 2020


Published on 24 May 2019. After co-founding SiriusXM Radio, Martine Rothblatt took a leap of faith when her youngest daughter developed a fatal lung illness with no available treatment. Determined to help her daughter, and with no formal background in science or biology, she created United Therapeutics, which developed a lifesaving molecule that not only saved her daughter, but tens of thousands of others in the process – proving that when your WHY is strong enough, you’ll find the HOW.   In this exclusive interview with Tony Robbins at one of his business seminars, Martine shares how she has built her entire career on achieving the seemingly impossible, and also reveals her own process for turning visionary ideas into technology that changes lives.

Philosophica
#487: Dr. Martine Rothblatt — A Masterclass on Asking Better Questions and Peering Into the Future

Philosophica

Play Episode Listen Later Dec 20, 2020 118:42


Podcast: The Tim Ferriss Show (LS 81 · TOP 0.01% what is this?)Episode: #487: Dr. Martine Rothblatt — A Masterclass on Asking Better Questions and Peering Into the FuturePub date: 2020-12-16Dr. Martine Rothblatt — A Masterclass on Asking Better Questions and Peering Into the Future | Brought to you by FreshBooks cloud-based small business accounting software, Headspace easy-to-use app with guided meditations, and Athletic Greens all-in-one nutritional supplement Dr. Martine Rothblatt (@skybiome) is Chairman and CEO of United Therapeutics, a biotechnology company she started to save the life of one of her daughters. The company offers FDA-approved medicines for pulmonary hypertension and neuroblastoma and is working on manufacturing an unlimited supply of transplantable organs.Dr. Rothblatt previously created and led Sirius XM as its Chairman and CEO and launched other satellite systems for navigation and international television broadcasting. In the field of aviation, her Sirius XM satellite system enhances safety with real-time digital weather information to pilots in flight nationwide. She also designed the world's first electric helicopter and piloted it to a Guinness world record for speed, altitude, and flight duration.In the legal arena, Dr. Rothblatt led efforts of the transgender community to establish their own health law standards and of the International Bar Association to protect autonomy rights in genetic information via an international treaty. She also published dozens of scholarly articles and papers on the law of outer space, resulting in her election to the International Institute of Space Law, and represented the radio astronomy community's scientific research interests before the Federal Communications Commission.She has bachelor's (communications studies, summa cum laude), JD (Order of the Coif) and MBA degrees from UCLA, which in 2018 awarded her its highest recognition, the UCLA Medal, and she holds a PhD in medical ethics from the Royal London School of Medicine and Dentistry. Her patented inventions cover aspects of satellite communication, medicinal biochemistry, and cognitive software.Dr. Rothblatt's recent books are on xenotransplantation (Your Life or Mine), gender identity (Transgender to Transhuman), and cyberethics (Virtually Human). She occasionally posts on Instagram at @transbinary and Twitter at @skybiome.Please enjoy!*This episode is brought to you by FreshBooks. I've been talking about FreshBooks—an all-in-one invoicing + payments + accounting solution—for years now. Many entrepreneurs, as well as the contractors and freelancers that I work with, use it all the time.FreshBooks makes it super easy to track things like expenses, project time, and client info, and then merge it all into great-looking invoices. FreshBooks can save users up to 200 hours a year on accounting and bookkeeping tasks. Right now FreshBooks is offering my listeners a free 30-day trial, and no credit card is required. Go to FreshBooks.com/Tim and enter “Tim Ferriss” in the “How did you hear about us?” section!*This episode is also brought to you by Headspace! Headspace is your daily dose of mindfulness in the form of guided meditations in an easy-to-use app. Whatever the situation, Headspace can help you feel better. Overwhelmed? Headspace has a 3-minute S.O.S. meditation for you. Need some help falling asleep? Headspace has wind-down sessions their members swear by. And for parents, Headspace even has morning meditations you can do with your kids. Headspace's approach to mindfulness can reduce stress, improve sleep, boost focus, and increase your overall sense of well-being.Go to Headspace.com/Tim for a FREE one-month trial with access to Headspace's full library of meditations for every situation.*This episode is also brought to you by Athletic Greens. I get asked all the time, “If you could only use one supplement, what would it be?” My answer is usually Athletic Greens, my all-in-one nutritional insurance. I recommended it in The 4-Hour Body in 2010 and did not get paid to do so. I do my best with nutrient-dense meals, of course, but AG further covers my bases with vitamins, minerals, and whole-food-sourced micronutrients that support gut health and the immune system. Right now, Athletic Greens is offering you their Vitamin D Liquid Formula free with your first subscription purchase—a vital nutrient for a strong immune system and strong bones. Visit AthleticGreens.com/Tim to claim this special offer today and receive the free Vitamin D Liquid Formula (and five free travel packs) with your first subscription purchase! That's up to a one-year supply of Vitamin D as added value when you try their delicious and comprehensive all-in-one daily greens product.*If you enjoy the podcast, would you please consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it really makes a difference in helping to convince hard-to-get guests. I also love reading the reviews!For show notes and past guests, please visit tim.blog/podcast.Sign up for Tim's email newsletter (“5-Bullet Friday”) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissFacebook: facebook.com/timferriss YouTube: youtube.com/timferrissThe podcast and artwork embedded on this page are from Tim Ferriss: Bestselling Author, Human Guinea Pig, which is the property of its owner and not affiliated with or endorsed by Listen Notes, Inc.

Podcast Notes Playlist: Latest Episodes
#487: Dr. Martine Rothblatt — A Masterclass on Asking Better Questions and Peering Into the Future

Podcast Notes Playlist: Latest Episodes

Play Episode Listen Later Dec 20, 2020 118:42


Tim Ferriss Show Podcast Notes Key Takeaways To find your purpose is the best feeling ever, Martine describes it as “a lightning bolt to your soul”Science is about critical thinking and asking ‘Why’To cultivate more science in society, we have to relate it to people’s everyday livesPharmaceutical companies should get consent before mining genome data from remote isolated communities for the purpose of medicine development“I would say that one of the greatest unmet medical needs today is an adequate supply of transplantable organs”“I am absolutely convinced that in this decade, the 2020s, we will be delivering manufactured organs by electric helicopter” – Martine RothblattIn the future, people will be able to wear headsets that stimulate the vagus nerve to target particular ailments, with no pills or medical expenses“I believe this kind of bridging of electronics and the mind is really right around the corner” – Martine RothblattThe ability to create a technology doesn’t necessarily grant the right to make it, that right is coupled with the obligation to have the consent of whoever may be adversely affected by itIn a future full of innovation, techno-ethics is a field with rich possibilitiesHumans spewing greenhouse gases into an undeniably thin atmosphere, yet fearing nuclear energy, will seem barbaric to future generations“Identify the corridors of indifference and run like hell down them” – Martine RothblattRead the full notes @ podcastnotes.orgDr. Martine Rothblatt — A Masterclass on Asking Better Questions and Peering Into the Future | Brought to you by FreshBooks cloud-based small business accounting software, Headspace easy-to-use app with guided meditations, and Athletic Greens all-in-one nutritional supplement Dr. Martine Rothblatt (@skybiome) is Chairman and CEO of United Therapeutics, a biotechnology company she started to save the life of one of her daughters. The company offers FDA-approved medicines for pulmonary hypertension and neuroblastoma and is working on manufacturing an unlimited supply of transplantable organs.Dr. Rothblatt previously created and led Sirius XM as its Chairman and CEO and launched other satellite systems for navigation and international television broadcasting. In the field of aviation, her Sirius XM satellite system enhances safety with real-time digital weather information to pilots in flight nationwide. She also designed the world’s first electric helicopter and piloted it to a Guinness world record for speed, altitude, and flight duration.In the legal arena, Dr. Rothblatt led efforts of the transgender community to establish their own health law standards and of the International Bar Association to protect autonomy rights in genetic information via an international treaty. She also published dozens of scholarly articles and papers on the law of outer space, resulting in her election to the International Institute of Space Law, and represented the radio astronomy community’s scientific research interests before the Federal Communications Commission.She has bachelor’s (communications studies, summa cum laude), JD (Order of the Coif) and MBA degrees from UCLA, which in 2018 awarded her its highest recognition, the UCLA Medal, and she holds a PhD in medical ethics from the Royal London School of Medicine and Dentistry. Her patented inventions cover aspects of satellite communication, medicinal biochemistry, and cognitive software.Dr. Rothblatt’s recent books are on xenotransplantation (Your Life or Mine), gender identity (Transgender to Transhuman), and cyberethics (Virtually Human). She occasionally posts on Instagram at @transbinary and Twitter at @skybiome.Please enjoy!*This episode is brought to you by FreshBooks. I’ve been talking about FreshBooks—an all-in-one invoicing + payments + accounting solution—for years now. Many entrepreneurs, as well as the contractors and freelancers that I work with, use it all the time.FreshBooks makes it super easy to track things like expenses, project time, and client info, and then merge it all into great-looking invoices. FreshBooks can save users up to 200 hours a year on accounting and bookkeeping tasks. Right now FreshBooks is offering my listeners a free 30-day trial, and no credit card is required. Go to FreshBooks.com/Tim and enter “Tim Ferriss” in the “How did you hear about us?” section!*This episode is also brought to you by Headspace! Headspace is your daily dose of mindfulness in the form of guided meditations in an easy-to-use app. Whatever the situation, Headspace can help you feel better. Overwhelmed? Headspace has a 3-minute S.O.S. meditation for you. Need some help falling asleep? Headspace has wind-down sessions their members swear by. And for parents, Headspace even has morning meditations you can do with your kids. Headspace’s approach to mindfulness can reduce stress, improve sleep, boost focus, and increase your overall sense of well-being.Go to Headspace.com/Tim for a FREE one-month trial with access to Headspace’s full library of meditations for every situation.*This episode is also brought to you by Athletic Greens. I get asked all the time, “If you could only use one supplement, what would it be?” My answer is usually Athletic Greens, my all-in-one nutritional insurance. I recommended it in The 4-Hour Body in 2010 and did not get paid to do so. I do my best with nutrient-dense meals, of course, but AG further covers my bases with vitamins, minerals, and whole-food-sourced micronutrients that support gut health and the immune system. Right now, Athletic Greens is offering you their Vitamin D Liquid Formula free with your first subscription purchase—a vital nutrient for a strong immune system and strong bones. Visit AthleticGreens.com/Tim to claim this special offer today and receive the free Vitamin D Liquid Formula (and five free travel packs) with your first subscription purchase! That’s up to a one-year supply of Vitamin D as added value when you try their delicious and comprehensive all-in-one daily greens product.*If you enjoy the podcast, would you please consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it really makes a difference in helping to convince hard-to-get guests. I also love reading the reviews!For show notes and past guests, please visit tim.blog/podcast.Sign up for Tim’s email newsletter (“5-Bullet Friday”) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim’s books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissFacebook: facebook.com/timferriss YouTube: youtube.com/timferriss

The Tim Ferriss Show
#487: Dr. Martine Rothblatt — The Incredible Polymath of Polymaths

The Tim Ferriss Show

Play Episode Listen Later Dec 16, 2020 118:42


Dr. Martine Rothblatt — The Incredible Polymath of Polymaths | Brought to you by FreshBooks cloud-based small business accounting software, Headspace easy-to-use app with guided meditations, and Athletic Greens all-in-one nutritional supplement Dr. Martine Rothblatt (@skybiome) is Chairman and CEO of United Therapeutics, a biotechnology company she started to save the life of one of her daughters. The company offers FDA-approved medicines for pulmonary hypertension and neuroblastoma and is working on manufacturing an unlimited supply of transplantable organs.Dr. Rothblatt previously created and led Sirius XM as its Chairman and CEO and launched other satellite systems for navigation and international television broadcasting. In the field of aviation, her Sirius XM satellite system enhances safety with real-time digital weather information to pilots in flight nationwide. She also designed the world’s first electric helicopter and piloted it to a Guinness world record for speed, altitude, and flight duration.In the legal arena, Dr. Rothblatt led efforts of the transgender community to establish their own health law standards and of the International Bar Association to protect autonomy rights in genetic information via an international treaty. She also published dozens of scholarly articles and papers on the law of outer space, resulting in her election to the International Institute of Space Law, and represented the radio astronomy community’s scientific research interests before the Federal Communications Commission.She has bachelor’s (communications studies, summa cum laude), JD (Order of the Coif) and MBA degrees from UCLA, which in 2018 awarded her its highest recognition, the UCLA Medal, and she holds a PhD in medical ethics from the Royal London School of Medicine and Dentistry. Her patented inventions cover aspects of satellite communication, medicinal biochemistry, and cognitive software.Dr. Rothblatt’s recent books are on xenotransplantation (Your Life or Mine), gender identity (Transgender to Transhuman), and cyberethics (Virtually Human). She occasionally posts on Instagram at @transbinary and Twitter at @skybiome.Please enjoy!*This episode is brought to you by FreshBooks. I’ve been talking about FreshBooks—an all-in-one invoicing + payments + accounting solution—for years now. Many entrepreneurs, as well as the contractors and freelancers that I work with, use it all the time.FreshBooks makes it super easy to track things like expenses, project time, and client info, and then merge it all into great-looking invoices. FreshBooks can save users up to 200 hours a year on accounting and bookkeeping tasks. Right now FreshBooks is offering my listeners a free 30-day trial, and no credit card is required. Go to FreshBooks.com/Tim and enter “Tim Ferriss” in the “How did you hear about us?” section!*This episode is also brought to you by Headspace! Headspace is your daily dose of mindfulness in the form of guided meditations in an easy-to-use app. Whatever the situation, Headspace can help you feel better. Overwhelmed? Headspace has a 3-minute S.O.S. meditation for you. Need some help falling asleep? Headspace has wind-down sessions their members swear by. And for parents, Headspace even has morning meditations you can do with your kids. Headspace’s approach to mindfulness can reduce stress, improve sleep, boost focus, and increase your overall sense of well-being.Go to Headspace.com/Tim for a FREE one-month trial with access to Headspace’s full library of meditations for every situation.*This episode is also brought to you by Athletic Greens. I get asked all the time, “If you could only use one supplement, what would it be?” My answer is usually Athletic Greens, my all-in-one nutritional insurance. I recommended it in The 4-Hour Body in 2010 and did not get paid to do so. I do my best with nutrient-dense meals, of course, but AG further covers my bases with vitamins, minerals, and whole-food-sourced micronutrients that support gut health and the immune system. Right now, Athletic Greens is offering you their Vitamin D Liquid Formula free with your first subscription purchase—a vital nutrient for a strong immune system and strong bones. Visit AthleticGreens.com/Tim to claim this special offer today and receive the free Vitamin D Liquid Formula (and five free travel packs) with your first subscription purchase! That’s up to a one-year supply of Vitamin D as added value when you try their delicious and comprehensive all-in-one daily greens product.*If you enjoy the podcast, would you please consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it really makes a difference in helping to convince hard-to-get guests. I also love reading the reviews!For show notes and past guests, please visit tim.blog/podcast.Sign up for Tim’s email newsletter (“5-Bullet Friday”) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim’s books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissFacebook: facebook.com/timferriss YouTube: youtube.com/timferriss

I'm Aware That I'm Rare: the phaware® podcast
Episode 357: PAH Today - Moving Forward

I'm Aware That I'm Rare: the phaware® podcast

Play Episode Listen Later Dec 16, 2020 17:08


SPECIAL EDITION: Moving Forward The PAH Initiative and United Therapeutics are excited to bring you the PAH Today National Broadcast Series. This series of virtual events is intended for adult patients with pulmonary arterial hypertension (PAH) and their caregivers. Advancements in the care and treatment of PAH are improving the lives of those impacted by this life-threatening disease. The National Broadcast Series will include insights and perspectives on today’s approaches to managing PAH from nationally recognized PAH healthcare providers. Join patients and caregivers across the nation to hear current considerations in the care of PAH. This is the 4th of 4 PAH Today broadcasts to learn about how you can be empowered to stay informed, motivated, and focused on your future. Presented by Dr. Lana Melendres-Groves the Director of the Pulmonary Hypertension Program at the University of New Mexico and PAH patients Denise B. & Lauren J. Learn more at: www.pahinitiative.com  Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Never miss an episode with the phaware® podcast app. Follow us @phaware on Facebook, Twitter, Instagram, YouTube & Linkedin Engage for a cure: www.phaware.global/donate #phaware #ClinicalTrials

I'm Aware That I'm Rare: the phaware® podcast
Episode 355 - PAH Today: The Pathways To Treatment

I'm Aware That I'm Rare: the phaware® podcast

Play Episode Listen Later Dec 9, 2020 22:50


SPECIAL EDITION: The Pathways To Treatment The PAH Initiative and United Therapeutics are excited to bring you the PAH Today National Broadcast Series. This series of virtual events is intended for adult patients with pulmonary arterial hypertension (PAH) and their caregivers. Advancements in the care and treatment of PAH are improving the lives of those impacted by this life-threatening disease. The National Broadcast Series will include insights and perspectives on today’s approaches to managing PAH from nationally recognized PAH healthcare providers. Join patients and caregivers across the nation to hear current considerations in the care of PAH. This is the 3rd of 4 PAH Today broadcasts to learn about how medications work to treat PAH and how finding the right combination of medications could help improve your symptoms. Presented by Dr. Lana Melendres-Groves the Director of the Pulmonary Hypertension Program at the University of New Mexico and Dr. Sean M. Studer Chief of Medicine at NYU-Woodhull Medical Center in Brooklyn, New York. Learn more at: www.pahinitiative.com  Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Never miss an episode with the phaware® podcast app. Follow us @phaware on Facebook, Twitter, Instagram, YouTube & Linkedin Engage for a cure: www.phaware.global/donate #phaware #ClinicalTrials

I'm Aware That I'm Rare: the phaware® podcast
Episode 353 - PAH Today: Shape the Future

I'm Aware That I'm Rare: the phaware® podcast

Play Episode Listen Later Dec 2, 2020 13:04


SPECIAL EDITION: How Decisions Today Can Shape the Future The PAH Initiative and United Therapeutics are excited to bring you the PAH Today National Broadcast Series. This series of virtual events is intended for adult patients with pulmonary arterial hypertension (PAH) and their caregivers. Advancements in the care and treatment of PAH are improving the lives of those impacted by this life-threatening disease. The National Broadcast Series will include insights and perspectives on today’s approaches to managing PAH from nationally recognized PAH healthcare providers. Join patients and caregivers across the nation to hear current considerations in the care of PAH. This is the second of 4 PAH Today broadcasts to learn about risk status, an important part of today's approach to treating PAH. You'll hear how risk status gives your healthcare provider a new way to assess your progress, and how it could help determine whether more can be done to improve your symptoms today and down the road. Presented by Dr. Lana Melendres-Groves the Director of the Pulmonary Hypertension Program at the University of New Mexico and Nurse Practitioner Melisa Wilson. Learn more at: www.pahinitiative.com  Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Never miss an episode with the phaware® podcast app. Follow us @phaware on Facebook, Twitter, Instagram, YouTube & Linkedin Engage for a cure: www.phaware.global/donate #phaware #ClinicalTrials

I'm Aware That I'm Rare: the phaware® podcast
Episode 351 - PAH Today: Beyond the Basics

I'm Aware That I'm Rare: the phaware® podcast

Play Episode Listen Later Nov 25, 2020 20:11


SPECIAL EDITION: Beyond the Basics The PAH Initiative and United Therapeutics are excited to bring you the PAH Today National Broadcast Series. This series of virtual events is intended for adult patients with pulmonary arterial hypertension (PAH) and their caregivers. Advancements in the care and treatment of PAH are improving the lives of those impacted by this life-threatening disease. The National Broadcast Series will include insights and perspectives on today’s approaches to managing PAH from nationally recognized PAH healthcare providers. Join patients and caregivers across the nation to hear current considerations in the care of PAH. This is the first of 4 PAH Today broadcasts to learn more about your symptoms and how your healthcare provider can use them to monitor your PAH. Presented by Dr. Lana Melendres-Groves the Director of the Pulmonary Hypertension Program at the University of New Mexico and Dr. George Ruiz Chief of Cardiology at MedStar Union Memorial Hospital. Learn more at: www.pahinitiative.com  Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Never miss an episode with the phaware® podcast app. Follow us @phaware on Facebook, Twitter, Instagram, YouTube & Linkedin Engage for a cure: www.phaware.global/donate #phaware #ClinicalTrials

NGMC Continuing Medical Education
PERT CME:Operationalizing PERT

NGMC Continuing Medical Education

Play Episode Listen Later Nov 19, 2020 62:10


Enduring CME will expire on 11/19/2022. Presenter: Sara Hegab, MD, Henry Ford Health System, Detroit, MI Objectives - Introduction and Case Presentation - Philosophy and Rationale - Set Up and Initiation - Operations - Performance - Challenges Disclosures - Research support: Henry Ford Hospital receives financial support in the form of research grants from Actelion, Bayer, United Therapeutics and Gilead in the area of pulmonary hypertension - Bayer-Speaker, Advisory Board Accreditation and Designation: The Northeast Georgia Medical Center & Health System, Inc. is accredited by the Medical Association of Georgia to provide continuing medical education for physicians. The Northeast Georgia Medical Center & Health System, Inc. designates this live activity for a maximum of 1 AMA PRA Category 1 Credit(s) TM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

NGMC Continuing Medical Education
PERT CME: Pulmonary Embolism Response Teams: Sometimes It Takes a Village

NGMC Continuing Medical Education

Play Episode Listen Later Nov 16, 2020 66:09


Enduring CME will expire on 11/16/2022. Presenter: Sara Hegab, MD, Henry Ford Health System, Detroit, MI Objectives •Challenges in management of patients with massive and submassivePE •Team based approach to PE management •Post-PE Syndrome Disclosures - Research support: Henry Ford Hospital receives financial support in the form of research grants from Actelion, Bayer, United Therapeutics and Gilead in the area of pulmonary hypertension - Bayer-Speaker, Advisory Board Accreditation and Designation: The Northeast Georgia Medical Center & Health System, Inc. is accredited by the Medical Association of Georgia to provide continuing medical education for physicians. The Northeast Georgia Medical Center & Health System, Inc. designates this live activity for a maximum of 1 AMA PRA Category 1 Credit(s) TM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Fun with the Maryland STEM Festival
Working on Lungs outside the body

Fun with the Maryland STEM Festival

Play Episode Listen Later Nov 5, 2020 9:38


Sam Popa, Associate Director, discusses his work at United Therapeutics on lungs outside the body that increases the success rate of donated organs. https://www.unither.com/index.html Follow the Festival on Twitter @mdstemfest, Instagram @mdstem, Facebook @marylandstemfestival and on our website www.marylandstemfestival.org. You can e-mail your thoughts and comments to us at mdstemfest@gmail.com

Steve Forbes: What's Ahead
S3E8: Making the Impossible Possible: A Conversation with Martine Rothblatt

Steve Forbes: What's Ahead

Play Episode Listen Later Oct 30, 2020 57:05


Future Positive
Innovating for Human Longevity with Dean Kamen and Martine Rothblatt

Future Positive

Play Episode Listen Later Jul 18, 2020 29:24


In this episode, our podcast host Dr. Emily Church looks at how technology is innovating modern medicine at an exponential rate to be smarter and proactive. In a special recording from Visioneering, XPRIZE founder Peter H. Diamandis is joined by two of the world’s greatest entrepreneurs: iBOT & Segway inventor engineer Dean Kamen, and science innovator and founder of United Therapeutics, Martine Rothblatt. They discuss the future of health and medicine where biology IS technology. Drawing from their own inspirational experience, including printing new organs, and eradicating diabetes and Alzheimers, Peter, Dean and Martine discuss the positive impact that innovation is having on human health and longevity. Recently named by Fortune as one of the “World’s 50 Greatest Leaders,” Peter H. Diamandis is the founder and executive chairman of the XPRIZE Foundation, which leads the world in designing and operating large-scale incentive competitions. He is also the executive founder of Singularity University, a graduate-level Silicon Valley institution that counsels the world's leaders on exponentially growing technologies. As an entrepreneur, Diamandis has started over 20 companies in the areas of longevity, space, venture capital and education. He is cofounder of BOLD Capital Partners, a venture fund with $250M investing in exponential technologies, and co-founder and Vice Chairman of Celularity, Inc., a cellular therapeutics company. Diamandis is a New York Times Bestselling author of two books: Abundance – The Future Is Better Than You Think and BOLD – How to go Big, Create Wealth & Impact the World. His newest book in this series of exponential technologies—The Future is Faster Than You Think—was released on January 28, 2020. He earned degrees in molecular genetics and aerospace engineering from the MIT and holds an M.D. from Harvard Medical School. Diamandis’ favorite saying is “the best way to predict the future is to create it yourself.”Dr. Martine Rothblatt founded Lung Biotechnology, as well as its parent company, United Therapeutics, in order to develop therapies for orphan diseases such as PAH. She earned her PhD in medical ethics from the Royal London School of Medicine and Dentistry, Queen Mary College, University of London and also obtained JD and MBA degrees from the University of California at Los Angeles. Prior to entering the life sciences field, Dr. Rothblatt was active in satellite communications, founding Sirius XM Satellite Radio and serving as its Chairman and CEO. She has also published many books, including Your Life or Mine: How Geoethics Can Resolve the Conflict Between Public and Private Interests in Xenotransplantation.Dean Kamen, Founder of FIRST and President of DEKA Research & Development CorporationDean Kamen is an inventor, an entrepreneur, and a tireless advocate for science and technology. His roles as inventor and advocate are intertwined—his own passion for technology and its practical uses has driven his personal determination to spread the word about technology's virtues and by so doing to change the culture of the United States.As an inventor, he holds more than 440 U.S. and foreign patents, many of them for innovative medical devices that have expanded the frontiers of health care worldwide. While still a college undergraduate, he invented the first wearable infusion pump, which rapidly gained acceptance from such diverse medical specialties as oncology, neonatology, and endocrinology. In 1976, he founded his first medical device company, AutoSyringe, Inc., to manufacture and market the pumps. Then, working with leading diabetes researchers, Dean pioneered the design and adoption of the first portable insulin pump. It was quickly demonstrated that using a pump could much more effectively control patients’ blood glucose levels. . At age 30, he sold AutoSyringe to Baxter Healthcare Corporation. Following the sale of AutoSyringe, Inc., he founded DEKA Research & Development Corporation to develop internally generated inventions as well as to provide research and development for major corporate clients. Kamen led DEKA's development of the HomeChoiceTM peritoneal dialysis system for Baxter International Inc. The HomeChoiceTM system allows patients to be dialyzed in the privacy and comfort of their home and quickly became the worldwide market leader. Kamen also led the development of technology to improve slide preparation for the CYTYC (now Hologic Inc.) ThinPrep® Pap Test. Kamen-led DEKA teams have also developed critical components of the UVARTM XTSTM System, an extracorporeal photophereisis device marketed by Therakos, a unit of Johnson & Johnson, for treatment of T-Cell lymphoma. An advanced prosthetic arm in development for DARPA should advance the quality of life for returning injured soldiers. Other notable developments include the HydroflexTM surgical irrigation pump for C.R. Bard, the CrownTM stent, an improvement to the original Palmaz-Schatz stent, for Johnson & Johnson, the iBOTTM mobility device, and the Segway® Human Transporter.Kamen has received many awards for his efforts. Notably, Kamen was awarded the National Medal of Technology in 2000. Presented by President Clinton, this award was in recognition for inventions that have advanced medical care worldwide, and for innovative and imaginative leadership in awakening America to the excitement of science and technology. Kamen was elected a member of the National Academy of Engineering in 1997. He was awarded the Lemelson-MIT Prize in 2002, and was inducted into the National Inventors Hall of Fame in May 2005. He is a Fellow of the American Institute for Medical & Biological Engineering, as well as many other national and international engineering organizations.In 2010, Dean hosted the Planet Green television series Dean of Invention.In addition to DEKA, one of Dean's proudest accomplishments is founding FIRST® (For Inspiration and Recognition of Science and Technology), an organization dedicated to motivating the next generation to understand, use and enjoy science and technology. Founded in 1989, this year FIRST® will serve more than 1,000,000 young people, ages 6 to 18, in more than 86 countries around the globe. Last year, high-school-aged participants were eligible to apply for more than $50 million in scholarships from over 200 leading colleges, universities, and corporations.Links: https://www.firstinspires.org/robotics/frchttps://www.unither.com/ See acast.com/privacy for privacy and opt-out information.

From Scratch with Jessica Harris
Martine Rothblatt

From Scratch with Jessica Harris

Play Episode Listen Later May 29, 2020 31:15


Martine is a pioneer in the satellite industry, launching companies including Geostar, PanAmSat, and Sirius Satellite Radio. She also founded United Therapeutics, a pharmaceutical company focused on cardiopulmonary disorders. In 2013, she became the highest paid female CEO in America. Martine is a helicopter pilot and a parent of four children. She also used to […]

Good News Good Planet
Printed Body Parts

Good News Good Planet

Play Episode Listen Later May 26, 2020 2:26


For more delicious news, go to www.GoodNewsGoodPlanet.com, and scroll to bottom for more ways to find the feel good stuff!* 3D PRINTED BODY PARTS Organ matches can be hard to come by. Patients typically wait for transplants for months, even years, sometimes dying before receiving them. But now there are companies combating the life-threatening organ shortage with 3D printing. The process is called "Bioprinting" and it uses human tissue cells as “ink”. It actually isn't a new idea. 3D printers can already make human skin and even retinas. But the method has been limited to small, thin tissues that lack blood vessels. New 3D printing technologies could soon change that. The Wake Forest Institute for Regenerative Medicine is creating artificial ears. A hydrogel scaffold is printed and then covered in skin and cartilage cells. These cells propagate, forming an ear-like structure. The original scaffold biodegrades, leaving the newly formed ear behind. By using the patient’s own cells, the organ has less chance of rejection once transplanted. United Therapeutics in New Hampshire is using a similar method to create lungs. A collagen infrastructure is 3D printed and then impregnated with human cells to animate it. The process, called "recellularization" is still in its early stages and not without challenges. The more complex an organ, the more difficult the task. Organs may someday be manufactured in large numbers, not only solving the organ shortage, but also reshaping our life spans. Imagine getting a new heart and lungs when your original ones give out. The future possibilities are exciting, though much further research and testing are still needed. While printing a 3D brain is a long way off, Sharon Presnell—chief scientist of Organovo whose company is 3D printing thin sheets of liver—says, “We all think it’s going to be possible at some point in the future. Where we differ, is on how long it will take.” *Hungry for more of the Good Stuff? Search "Good News Good Planet" on YouTube, Instagram, Patreon, Alexa and wherever you listen to your favorite podcasts.

I'm Aware That I'm Rare: the phaware® podcast

Avi Halpert is Vice President, Corporate Real Estate at United Therapeutics. In this episode, Avi discusses his role of overseeing the development of UT's Silver Spring, Maryland headquarters as well as site development of their North Carolina facilities to meet corporate energy goals. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Never miss an episode with the phaware® podcast app. Follow us @phaware on Facebook, Twitter, Instagram, YouTube & Linkedin Engage for a cure: www.phaware.global/donate #phaware

ideacity On The Air
Martine Rothblatt - Flying Cars & Artificial Organs

ideacity On The Air

Play Episode Listen Later Feb 12, 2020 20:00


Martine and Moses talk about viable ways people can live longer

Trans Resister Radio
One World One Sphere, Unisphere, AoT#243

Trans Resister Radio

Play Episode Listen Later Sep 3, 2019 59:10


This episode of The Age of Transitions radio show covers the forceful land deals of influential players, transhumanism, and the infamous Octopus conspiracy made famous by Danny Casolaro. The new Unisphere facility, corporate headquarters of United Therapeutics, is a main focus during the conversation.  topics include: transhumanism, transhumanists, Martine Rothblatt, biotech, pharmaceuticals, pulmonary arterial hypertension, drugs, Ewing Cole, Maryland flag, Washington DC, Lake Buena Vista, Disney World, Florida, CIA, Danny Casolaro, Indio CA, Cabazon Band of Mission Indians, reservation, Fantasy Springs, Wackenhut, California, tribal land, art, Rachel Haywire, transhumanist party

Clinical Research Podcast
United Therapeutics - Glassdoor Review - EP. 8

Clinical Research Podcast

Play Episode Listen Later Jun 22, 2019 35:45


In this episode we talk about United Therapeutics. The first sponsor in the glassdoor review series. I hope you enjoy this one. Don't forget to Subscribe for new content! Subscribe: https://youtube.com/eliteclinicalrese... Call or Text: 910-502-3732 Email: eliteclinicalgroup@gmail.com Podcast: https://anchor.fm/clinical-research-p... Steemit: https://steemit.com/@ecrgmedia Advertise: eliteclinicalgroup@gmail.com Watch: » Industry News: https://goo.gl/fNXpQ5 » All Videos: https://goo.gl/87XEFW » Interview Recaps: https://goo.gl/wJsk6W » Glassdoor Reviews: https://goo.gl/AbQzqe We do: » Insider Interviews » Resume Reviews » Question and Answer » Discuss all things Clinical Research » News and Product Reviews » Education --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/clinical-research-podcast/message Support this podcast: https://anchor.fm/clinical-research-podcast/support

The Tony Robbins Podcast
The Wonder Woman who might save your life | Meet Martine Rothblatt, Sirius XM co-founder who now creates life-saving technologies

The Tony Robbins Podcast

Play Episode Listen Later May 24, 2019 56:14


After co-founding SiriusXM Radio, Martine Rothblatt took a leap of faith when her youngest daughter developed a fatal lung illness with no available treatment. Determined to help her daughter, and with no formal background in science or biology, she created United Therapeutics, which developed a lifesaving molecule that not only saved her daughter, but tens of thousands of others in the process – proving that when your WHY is strong enough, you’ll find the HOW.   In this exclusive interview with Tony Robbins at one of his business seminars, Martine shares how she has built her entire career on achieving the seemingly impossible, and also reveals her own process for turning visionary ideas into technology that changes lives.

FirstWord Pharmaceutical News
FirstWord Pharmaceutical News for Thursday, November 15 2018

FirstWord Pharmaceutical News

Play Episode Listen Later Nov 15, 2018 5:09


Today in FirstWord:

Industry Focus
Healthcare: MannKind's Back from the Brink

Industry Focus

Play Episode Listen Later Sep 5, 2018 27:32


A new cash lifeline from United Therapeutics buys the diabetes drugmaker more time to increase sales of its inhaled insulin. Also, make-or-break news is fast approaching for cardiovascular drugmaker, Amarin. MNKD, UTHR, AMRN

MizMaryland | Soul Force Politics
021 — Dr. Martine Rothblatt: A Genius Mind and a Noble Heart

MizMaryland | Soul Force Politics

Play Episode Listen Later Apr 18, 2018 52:17


Today’s guest is a truly remarkable genius, tenacious innovator, and creative problem solver. She also happens to be one of the kindest, most generous, and caring humans I have met. If you have never heard Martine Rothblatt speak of the many ways she has conquered the impossible, then buckle up for a sweet ride on today’s show where we meet the blending of a genius mind with a noble heart. Her insatiable curiosity has produced everything from satellite radio and life-saving pharmaceuticals to improved lung transplantation techniques, development of potential pig-to-human organ transplants, to the first prototypes for electric helicopters, and building robotic cybernetic companions. She is a futurist of the highest order – one that does not just predict; Martine Rothblatt DELIVERS. She has a law degree, an MBA, and a PhD in medical ethics. Dr. Rothblatt is the founder and former CEO and Chairman of Sirius XM satellite radio, the founding CEO and pioneer of an orphan drug at United Therapeutics that saved the life of her own child before making millions of dollars saving the lives of others, and a futurist that tells us what she sees in the fields of artificial intelligence, mind files, and the exploration of consciousness. Each week at the end of our show, you hear me encourage you with words that I use as my own personal daily mantra: Be the change you want to see. Create the world you want to manifest. Break through the illusions of impossibility. Live your life’s purpose with clarity, intention, and truth. Choose only love. Be. ONE. Martine Rothblatt encompasses all of this in the most magnificent way. Thank you for joining us today to listen to her wisdom. ______________ In the first video below, Morgan Freeman meets the robot Bina 48 on his National Geographic show, “The Story of God.” And after seeing this, Whoopi Goldberg went to interview Martine and Bina Rothblatt for a segment for ABC’s “The View.” Martine Rothblatt was named one of the “100 Greatest Living Business Minds” by Forbes Magazine

FirstWord Pharmaceutical News
FirstWord Pharmaceutical News for Monday, August 7 2017

FirstWord Pharmaceutical News

Play Episode Listen Later Aug 7, 2017 1:48


Bill Murphy's  RedZone Podcast | World Class IT Security
#067: Shola: A CIO's Journey To Solving Global Grand Health Challenges| Lessons in Innovation| Mentorship| & Continuous Learning

Bill Murphy's RedZone Podcast | World Class IT Security

Play Episode Listen Later Jan 6, 2017 37:57


My guest for this episode is Shola Oyewole, CIO of United Therapeutics. As a member of the Senior Executive Leadership of United Therapeutics Corporation, Shola provides technology, vision, and leadership in the development and implementation of the global information technology (IT) program. In that role he supports the Finance, HR, R&D, Manufacturing, Sales & Marketing, and various business units in planning and implementing enterprise information systems to support both distributed and centralized business operations, and achieve more effective and cost beneficial enterprise-wide IT operations. Additionally, Shola provides strategic and tactical planning, budget development, evaluation, and coordination of the information and technology systems for the corporation. He facilitates communication between staff, management, vendors, and other technology resources within (and outside) of the organization. Major Take-Aways From This Episode: 1. In our discussion we highlighted the importance of continuous learning in not just tech domain but all elements leadership, innovation and team building for example. 2. The Importance of mentors. 3. Innovation and help desk ideas that will spark your imagination 4. Branding and marketing an IT Dpt. Click here see an example of the logo below for his team that was developed related to the marketing and branding of the IT department. 5. Stories of how Shola said 'Yes' to requests his CEO made that lead to major new sources of revenue for the company. Ways to connect with SholaPrabhash Shrestha: LinkedIn Twitter Other Resources: United Therapeutics Website Advanced Therapies For Patients Suffering with PAH, CIO Review Harvard Business School Classes Singularity University Click Here for Time Stamped Show Notes Sponsored By: ________________________________________ This episode is sponsored by the CIO Security Scoreboard, a powerful tool that helps you communicate the status of your IT Security program visually in just a few minutes. ________________________________________ Credits: Outro music provided by Ben's Sound Other Ways To Listen to the Podcast iTunes | Libsyn | Soundcloud | RSS Feed | LinkedIn Leave a Review If you enjoyed this episode, then please consider leaving an iTunes review here. Click here for instructions on how to leave a review if you're doing this for the first time. About Bill Murphy Bill Murphy is a world renowned IT Security Expert dedicated to your success as an IT business leader. Follow Bill on LinkedIn and Twitter.

FirstWord Pharmaceutical News
FirstWord Pharmaceutical News for Wednesday, March 11, 2015

FirstWord Pharmaceutical News

Play Episode Listen Later Mar 11, 2015 1:39


FirstWord Pharmaceutical News
FirstWord Pharmaceutical News for Monday, September 1, 2014

FirstWord Pharmaceutical News

Play Episode Listen Later Sep 1, 2014 19:52