Podcasts about yopp

When a group of young moms died around the same time, clinicians Dr. Justin Yopp and Dr. Don Rosenstein wanted to refer their widowed spouses to a grief support group… but none existed. So they started their own.  In this conversation, Kate, Justin, and Don discuss: The grief of imagined futures  The particular needs of parents with cancer and those of widowed parents How to talk to kids about cancer  How to parent while you have cancer Together, they uncover the magic of we. This summer, we are re-sharing our all-time favorite episodes. While this conversation originally aired in 2020, Kate caught up with Don and Justin to get an update on what they are working on lately. You won't want to miss their important (and practical!) update.   Watch clips from this conversation, read the full transcript, and access discussion questions by clicking here or visiting katebowler.com/podcasts. Follow Kate on Instagram, Facebook, or X (formerly known as Twitter)—@katecbowler. Links to social pages and more available at linktr.ee/katecbowler.See omnystudio.com/listener for privacy information.

Depois do meu vídeo em que falo que a Olympikus e Fila não tem tênis na listagem de tênis autorizados para uso em prova, o que dizer das grandes marcas que, propositadamente, fazem tênis que não podem ser usados por atletas de elite nas provas por infringirem as normas da World Athletics? | A Maratona de Blumenau já foi uma das provas de 42 km mais importantes do Brasil e onde normalmente os corredores batiam seus recordes pessoais por causa do percurso plano e clima frio. Depois de um grande hiato, ela está de volta e será disputada no dia 23 de julho - Mais informações e inscrições - https://maratonadeblumenau.com.br/ Entrevista com Raul Cardozo, diretor da Maratona de Blumenau - https://youtube.com/live/yM4o_Zex2MU | Óculos YOPP da Maratona do Rio - https://www.yopp.com.br/maratonarj | HISTÓRICO DE PROVAS DA YESCOM - https://www.yescom.com.br/site/historico.html | PARCEIROS | GEIS DE CARBOIDRATO Z2 - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.z2foods.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ - Use o cupom CORRIDANOAR para ter 10% de desconto | PULSEIRAS DE IDENTIFICAÇÃO SELFID - ⁠⁠⁠⁠https://www.selfid.com.br/⁠⁠⁠⁠ use o CUPOM "CNA2019" 10% de desconto | ÓCULOS YOPP - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://cnoar.run/oculosyopp⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ - Use o cupom "corridanoar10" para ter 10% de desconto em todo o site | PROVAS LIVE! RUN XP - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://liverun.com.br/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ | use o cupom CORRIDANOAR para ter 20% de desconto | PRODUTOS CORRIDA NO AR e CAFÉ & CORRIDA ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.runfor.com.br/corrida-no-ar⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ | Use o cupom "CAFEECORRIDA10" para ter 10% de desconto | Comunidade CORRIDA NO AR no Whatsapp: Use os convites para entrar nos grupos: PROVAS - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://cnoar.run/provas⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ | SÓ PARA MULHERES - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://chat.whatsapp.com/C8BScuZ7HpsFUl9ynbK4pP⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ TREINAMENTO - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://cnoar.run/treinamento⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ TÊNIS - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://cnoar.run/tenis⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ACESSÓRIOS - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://cnoar.run/acessorios⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ LESÕES - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://cnoar.run/lesoes⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ CAFÉ & CORRIDA - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://cnoar.run/cafeecorrida⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ CLASSIFICADOS (NOVOS & USADOS) - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://chat.whatsapp.com/H8w33DIHyxKKNJqHP9bAPN⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  CUPONS & LINKS - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://cnoar.run/CuponseLinks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ OUTRAS DISCUSSÕES - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://cnoar.run/OutraDiscussoes⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ | DIVULGUE SEU TRAMPO (YT, IG, TT, podcast) -  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://chat.whatsapp.com/GoRqaytc3h58loJztY7KAS⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ DIVULGAÇÃO DE EVENTOS (provas, treinões e cia) - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://chat.whatsapp.com/IQGNacRUIVLA8axQl9iFBs⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ | O Café & Corrida é uma live que rola de segunda à sexta, às 6 da manhã e às 6 da tarde no Youtube e depois vira podcast que está disponível nos principais agregadores

This week, Nick Averwater continues his conversation with Dr. Mike Yopp, Director of Bands at Middleton High School in Middleton, TN, a town of just a few hundred people in the southwestern part of the state. The high school serves Middleton and several surrounding communities as part of the Hardeman County School District. In March of 2023, a few weeks after this conversation, it was announced that, in the Fall, Dr. Yopp will be relocating to Freed-Hardeman University in Henderson, TN where he will be a professor, and Director of the newly-formed jazz band.In this episode we'll learn more about the recruitment strategies and philosophies that have served Dr. Yopp so well in seven different programs at the high school and college level.Our conversation was recorded January 26, 2023. We've broken it up into two episodes, and this is part two.

This week, Nick Averwater talks with Dr. Mike Yopp, Director of Bands at Middleton High School in Middleton, TN. Middleton is a town of just a few hundred people in the southwestern part of the state, but the high school serves several surrounding communities as part of the Hardeman County School District. In March of 2023, a few weeks after this conversation, it was announced that Dr. Yopp will be taking on a new role as a professor and Director of the jazz band at Freed-Hardeman University in Henderson, TN.In this episode he'll tell us about the people and experiences that inspired him to become a music educator, but the majority of the conversation will focus on his strategies and philosophies about recruitment, something he has been very successful at doing at both the high school and college level.Our conversation was recorded January 26, 2023. We've broken it up into two episodes, and this is part one.

The Widower's Journey Podcast is pleased to announce that we have landed an interview with Dr. Justin Yopp, Ph.D., Associate Professor at the North Carolina University Department of Psychiatry and co-author of the intriguing book, The Group – Seven Widowed Fathers Reimagine Life. Listen as your host, Herb Knoll, and Dr. Yopp discuss the background in writing The Group, and highlighted many of the best practices the seven widowed fathers devised as they raised their children as single parents.   

Anastasia Yopp Candidate for Connecticut State Representative

Candidate for State Rep, Anna Yopp joins the show

Anastasia Yopp for State Rep 20th District

 Anastasia Yopp for State Rep 20th District

Why can some people ignore the facts about President Joe BidenHey Limousine Liberals,Are you willing to let an illegal immigrant family move in with YOU?Have the same old political parties ruined democracy for America?What will 2024 Look like ?Today's Guest:CT GOP candidate for Attorney General @Jessica KordasWeekly Contributor Retired NYPD Detective Chris StromCT GOP candidate for state rep Anastasia YoppAuthor and media personality Dan WosFriday Panel special guestTexas Warrior Raven HarrisonFounder Of Patriot Podcast Network and host of The Great Divide with Alan JacobyCandidate for Lt Gov in Colorado Darryl Gibbs for ColoradoAaron Lewis for CT "Connecticut"Support the show

David fills us in on the exciting things in Memphis, Tennessee including the new Flip Side Memphis (pinball & food) location. Plus, David talks about his legendary Yoppsicles that can […]

Organizer Debbie Yopp discusses the Brew n Que Festival coming to George Ingalls Equestrian Center in Norco. 

My name is John Yopp and I am running for Onslow County Sheriff as a Republican Candidate. ​ I am a lifelong resident of Onslow County. I care deeply about the people that live in our community. My family has been living in Onslow County, NC since the 1790s.  We even have a road named after us, Yopp Road. We are known as a hardworking and reliable family willing to help and serve our fellow citizens.  For the past 20 years, I have faithfully dedicated my life to serving the people in this community. ​ On September 11th, 2001, I had an interview with the Onslow County Sheriff's Office. While in the waiting room, I watched the atrocious acts of terrorism unfold in New York City on the tv screen. Despite the chaos, danger, and imminent threat, I watched the selfless bravery of police officers, EMS workers, and firefighters, as they ran into doomed buildings to save people they didn't even know, and this strengthened my commitment and propensity to serve.  PRINCIPLED, CONSISTENT LEADERSHIP SERVING ONSLOW COUNTY In 2001, I began serving as a Correctional Officer in the Onslow County Jail. From there, I assumed the role of patrol deputy for the Onslow County Sheriff's Office and continued to work there for several years. I am currently a Sergeant for the North Topsail Beach Police Department. My entire law enforcement career has been spent working in Onslow County, doing my best to ensure the best possible outcome for each and every citizen I have been called to serve.

Today we talk to Dr. Justin Yopp about the widowed parent program he and a colleague began after noting a lack of group support particularly for young father's recently bereaved.  https://widowedparent.org Dr. Yopp is a clinical psychologist and Assistant Professor in the Department of Psychiatry at UNC. He is a member of the UNC Comprehensive Cancer Support Program at the North Carolina Cancer Hospital where he provides inpatient as well as outpatient assessment and therapeutic services for children and adolescents with cancer. He also works with children whose parents have serious medical illnesses such as cancer. His research is in the area of children's adaptation to cancer. Dr. Yopp came to UNC from St. Jude Children's Research Hospital in Memphis, TN, where he served as a clinical psychologist and coordinator of the inpatient consultation-liaison service. Prior to working at St. Jude, Dr. Yopp completed his internship and postdoctoral fellowship at Nationwide Children's Hospital in Columbus, Ohio. He earned his doctoral degree in clinical psychology from Central Michigan University and completed a pediatric psychology externship at Children's Hospital of Michigan. He is a native of Raleigh.    

Dans ce nouvel épisode, je suis ravie de vous partager ma conversation avec Yannick. Yannick est éducatrice canine aux multiples casquettes. Dans cette discussion, elle retrace son parcours avec Yopp et Yeti, ses deux fidèles compagnons qui l'accompagnent dans toutes ses aventures. Passionnée et spécialisée en sport canin, Yannick nous raconte son expérience de la compétition et nous explique comment elle accompagne les chiens sportifs tout au long de leur vie. Engagée pour l'intégration du chien dans notre société, Yannick nous parle aussi de son travail depuis plus de 15 ans aux côtés de la Métropole de Lyon et nous donne des conseils pour agir à notre échelle. Sommaire :  00:10 : Présentation du podcast 01:24 : Présentation de Yannick, Yeti et Yopp  07:30 : Son parcours d'éducateur canin 11:00 : Présentation de Canissimo 17:00 : Sa pratique des sports canins 24:20 : Transmettre sa passion des sports canins  31:50 : Sa collaboration avec la Métropole de Lyon 37:30 : L'intérêt de rester patt'partout (chien et humain) 44:45 : Conseils pour débuter le sport avec son chien et s'impliquer  53:20 : Soutenir le podcast On en parle dans cet épisode : Le compte Instagram de Canissimo : https://www.instagram.com/canissimo.sportscanins/ La page Facebook de Canissimo : https://www.facebook.com/Canissimo.lyon La page Facebook de Yannick : https://www.facebook.com/yannick.thouloncanissimo Le site internet de Yannick : http://www.canissimo.fr/ Catherine Collignon Camille N'Guyen - Muzo+ : https://muzoplus.fr/ Treating Separation Anxiety in dogs - Malena Demartini Price Lives de la Karen Pryor Academy Poursuivez votre écoute en suivant La Niche sur : Le site : http://laniche-podcast.fr/ Instagram : https://www.instagram.com/lanichepodcast/ Facebook : https://www.facebook.com/lanichepodcast YouTube : https://www.youtube.com/channel/UC8FGY3ZcycTD6AfcTVNaIKA Musique : Dolling - Cybersdf Source: https://soundcloud.com/cybersdf Licence: https://creativecommons.org/licenses/by/3.0/deed.fr Téléchargement (6MB): https://auboutdufil.com/?id=502

InvicTech's CEO, Patrick Yopp, joins Coruzant Technologies for the Digital Executive podcast. He shares how you need to commit to something bigger than yourself. It will humble, challenge, and it will make you grow in significant ways.  At the end of the day, you must learn to trust yourself.

The IcePod goes live and Antarctic! For our first live episode that we broadcasted during the APECS workshop "Antarctic Science: Global connections", we met with the Australian weather observer and Ph.D. candidate Vicki Heinrich. Well, actually, it wasn't only Vicki but we had another special guest: Vickie's pet cat sneaking around.  For more than ten years, Vicki has been a regular in the Antarctic to look at the clouds and play with balloons, all courtesy of the Australian Bureau of Meteorology (BoM). To be trained on the ten types of clouds, she found this opportunity once in a newspaper, and it saved her from the mining industry. To get paid to stay twelve months at a weather station in Antarctica still feels extraordinary to her – as are the beauty of the Antarctic icescape and the many friendships she has built along the way, both with colleagues and penguin colonies. So why did Vicki then move into psychology? In 2019, she started her Ph.D. thesis with the project "Use of Weather and Climate Information: Risk perception and decision-making in the Antarctic" in order to learn more about how people use weather information to make their daily decisions. To get to know the other side – the user's perspective – is clearly an add-on to her career, and to us as her project got YOPP-endorsed. It turns out – as a preliminary result – everybody wants to know about the wind.For updates and other materials, check also our website: https://theicepodcast.home.blog/If you want to know more about the Association for Polar Early Career Scientist check the APECS website at https://apecs.is/More about the APECS workshop "Antarctic Science: Global connections" can be found at https://www.apecs.is/events-archive/390-scar-2020-workshop.html?layout=*Read about Vicki's project at https://www.facebook.com/UWCIAntarctica or at the YOPP-endorsement projects overview https://apps3.awi.de/YPP/The IcePod is the podcast about polar science and the people. We'll talk to scientists who went on board Polarstern, the German research icebreaker, for the biggest research expedition in the Arctic. The IcePod is the official podcast of the Year of Polar Prediction initiative to improve weather and sea-ice forecast in the Arctic and Antarctic. Editorial responsibility: Kirstin Werner and Sara Pasqualetto Music from https://filmmusic.io"Sweeter Vermouth" by Kevin MacLeod (https://incompetech.com) Licence: CC BY (https://creativecommons.org/licences/by/4.0/) Photo credit: Peter Hargreaves

The evidence God was well aware of the times we are living in, and planned a way of escape, continues to grow! Let's look at a special word by Jonathan Cahn at "The Return" on September 26th. And afterwards, let's respond with a "Yopp."The Return: https://youtu.be/D8whU4HxyjA Jonathan Cahn's message is found at 2:00

Savannah Yopp is a sophomore attending Cranbrook Kingswood Upper school. She has been training classical ballet since she was 7 years old and she has always had great interest in the arts. Savannah talks about how she used to walk around in tippy toes when she was young, her favorite memory with a ballet company, and the power of teleportation.

When a group of young moms died around the same time, clinicians Justin Yopp and Don Rosenstein wanted to refer their widowed spouses to a grief support group... but none existed. So they started their own. Kate, Justin, and Don discuss the loss of imagined futures and the particular needs of young, widowed parents. Together, they uncover the magic of we.CW: Doctors describe their work with patients who have cancer, death of a spouseFor show notes, the transcript, and discussion questions: https://katebowler.com/podcasts/justin-yopp-and-don-rosenstein-the-magic-of-we/ To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoicesSee omnystudio.com/listener for privacy information.

When a group of young moms died around the same time, clinicians Justin Yopp and Don Rosenstein wanted to refer their widowed spouses to a grief support group... but none existed. So they started their own. Kate, Justin, and Don discuss the loss of imagined futures and the particular needs of young, widowed parents. Together, they uncover the magic of we. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Here is the second episode on the YOPP Targeted Observing Periods, or TOPs. This time, we speak to Thomas Jung, head of the section Climate Dynamics at the German Alfred Wegener Institute and professor for Physics of the Climate System at the University of Bremen. Even more important, as the chair of the Polar Prediction Project's Steering Group, he is the captain and structured mind behind YOPP and PPP. His ability to chair a meeting even with fever from his bed not only provides him with all the skills needed to steer the Polar Prediction Project during a pandemic, but has been the ultimate test of his leadership skills. Keeping a healthy balance between management and science is probably his secret to success, in addition to creating extensive but ultrapractical mindmaps and building an international network across the academic community and forecasting experts. Thomas has also been the winner of our YOPP TOP Twitter challenge. How did he overcome the jumpiness of forecast? Here, he unveils his secret: Well, it's just like planning your next barbecue weekend (something we all look forward to during this COVID-19 summer). Take your time between an ice cream and a cold drink and listen to this episode for a look behind the scenes of YOPP, how the project came to life and how it still surprises its master of mind maps and virtual meetings.  For updates and other materials, check also our website: https://theicepodcast.home.blog/Arctic Drift Audiologbuch (in German): https://open.spotify.com/show/2f321wQiWNhIpGdi57aoRr?si=h9pA2a8BRJS4Xh-xQSM63AThe IcePod is the podcast about polar science and the people. We'll talk to scientists who went on board Polarstern, the German research icebreaker, for the biggest research expedition in the Arctic. The IcePod is the official podcast of the Year of Polar Prediction initiative to improve weather and sea-ice forecast in the Arctic and Antarctic. Editorial responsibility: Kirstin Werner and Sara Pasqualetto Music from https://filmmusic.io"Sweeter Vermouth" by Kevin MacLeod (https://incompetech.com) Licence: CC BY (https://creativecommons.org/licences/by/4.0/) Photo credit: Martina Buchholz (Alfred Wegener Institute)

The Group offers a singular perspective on grief by weaving together the latest thinking on bereavement, resiliency and post-traumatic growth with the true story of seven men who were raising children on their own after the deaths of their wives. The men connected with each almost immediately, and over the next several years forged a deep bond as their monthly meetings evolved into a forum for healing and personal reinvention that transformed them in unexpected ways.The authors co-led the support group and partnered with the men to write their story, which is interspersed with the latest in bereavement research conveyed in an easily relatable way. The fathers' touching efforts to care for themselves, their families, and each other offers a gripping narrative that shows how each of us has the potential to rebuild new and meaningful lives. Powerful, enlightening and hopeful, The Group will help you make sense of grief and inspire you to reimagine your life moving forward.Justin Yopp, PhD, is a clinical psychologist and Associate Professor of Psychiatry at the University of North Carolina at Chapel Hill where he directs the pediatric psycho-oncology consultation services within the UNC Comprehensive Cancer Support Program.https://www.amazon.com/Justin-M-Yopp/e/B076J6P5QB/ref=dp_byline_cont_pop_book_2 See acast.com/privacy for privacy and opt-out information.

In 2010 Dr. Justin Yopp and his colleague, Don Rosenstein, piloted a support group for widowed dads that grew into being part of the Widowed Parent Project. A decade later, Dr. Yopp and his team continue to learn from widowed parents about the unique challenges of grieving their partner, raising children as a solo parent, and forming a new trajectory for their lives and their families.  Learn more about the Widowed Parent Project. Read The Group: Seven Widowed Fathers Reimagine Life *all proceeds from the book go directly to the Widowed Parent Project.* Watch Dr. Yopp's TEDx Talk

On Today's episode of Ask a Death Doula, my guest is Justin M. Yopp, PhD,. Justin Yopp is a clinical psychologist and Associate Professor in the Department of Psychiatry at the University of North Carolina at Chapel Hill. As a member of UNC’s Comprehensive Cancer Support Program, Dr. Yopp offers psychotherapy, assessment, and consult-liaison services for both pediatric oncology and adult oncology populations at the N.C. Cancer Hospital. Dr. Yopp also co-leads the Widowed Parent Program (www.widowedparent.org), which offers support groups for parents who have lost a spouse or partner and are raising children on their own and conducts research to support grieving families. He co-authored The Group: Seven Widowed Fathers Reimagine Life (Oxford Press), which weaves together contemporary thinking on grief, adaptation and resiliency with the true story of the men from their first support group. Prior to joining the faculty at UNC, Dr. Yopp served as a psychologist at St. Jude Children's Research Hospital. links mentioned in this Interview:: ** website: www.widowedparent.org ** TED talk: https://www.ted.com/talks/justin_yopp_more_than_grief_how_seven_fathers_reimagined_life_after_loss ** Book:The Group: Seven Widowed Fathers Reimagine Life The Group: How Seven Widowed Fathers Reimagine Life

Here is the first episode!In an interview with us, climate scientist Thomas Rackow talks about his duties as a YOPP modelling lecturer for the MOSAiC school aboard the Russian research icebreaker Akademik Fedorov that accompanied Polarstern on her transit into the central Arctic sea ice in September and October 2019. It's all about first times: not only Rabe Socke went to the Arctic for the first time, but also Thomas had his first glimpse of northern lights, and got the polar virus. How is it to put your first step on Arctic sea ice and at the same time becoming a VIP by carrying a walkie-talkie around? Thanks to T-Racks, everyone on board Akademik Fedorov is able now to predict where the sea ice goes and sing along with Thomas on his ukulele.And by the way: if you miss the music, find the very special playlist by Thomas on Spotify: https://open.spotify.com/playlist/1TvucfsBWJ3VrJtOukAsQF?si=GoFc5_XVTNm8HiLPOjF3ggIf you want to listen to the full episode with music, check back with us: polarprediction@gmail.comFor updates and other materials, check also our website: https://theicepodcast.home.blog/Arctic Drift Audiologbuch (in German): https://open.spotify.com/show/2f321wQiWNhIpGdi57aoRr?si=h9pA2a8BRJS4Xh-xQSM63ACuriously Polar: https://open.spotify.com/show/0HqZdOUwP78cF8em0nQ9Rp?si=zXBuvoCATae7HGWrBpuudQThe IcePod is the podcast about polar science and the people. We'll talk to scientists who went on board Polarstern, the German research icebreaker, for the biggest research expedition in the Arctic. The IcePod is the official podcast of the Year of Polar Prediction initiative to improve weather and sea-ice forecast in the Arctic and Antarctic.Editorial responsibility: Kirstin Werner and Sara PasqualettoMusic from https://filmmusic.io"Sweeter Vermouth" by Kevin MacLeod (https://incompetech.com)Licence: CC BY (https://creativecommons.org/licences/by/4.0/)Photo credit: Sam Cornish

ENCORE EPISODE - originally published January 16, 2019 I had such a great discussion with Dr. Justin Yopp of the University of North Carolina for this episode. Justin is a clinical psychologist and is co-author of the book, “The Group: Seven Widowed Fathers Reimagine Life.” I really enjoyed our wide-ranging discussion. It was a fascinating mix of practical and academic, and included some great stories from the widowed dads in the book about their experiences. Some of the topics we covered include: the dual process model of coping and bereavement; post-traumatic growth; the concept of being a ‘good enough' parent; the unique hardships of being a widowed father; and the research into the needs of widowed parents being conducted at UNC. By the way, if you're a widowed mom or dad with kids 18 & under at home, and widowed less than three years, I'd encourage you to answer the survey on their web site…this is such important work and, surprisingly, there is very little research that's been done on the needs of widowed parents. Look for the link in the show notes for episode 9. I hope you enjoy my discussion with Dr. Justin Yopp.

Discuss on Reddit ➤ Support the Show ➤ We meant what we said, and we said what we meant: this podcast is faithful 100%. Faithful, that is, in our commitment to talk all about Ahrens and Flaherty’s Broadway flop-turned-amateur success story ‘Seussical the Musical!’ With it’s time on Broadway being tumultuous at best, Jimi and Tommy band together to work out what went wrong and why this show has such a fantastic life outside of the Great White Way. With backstage drama, complex book dissections and plenty of made-up words this Happy Hour is one not to be missed! Seussical the Musical (Original Broadway Cast) Amazon / iTunes / Spotify Zania is the Dr. Seuss inspired word of the day. Get it trending! Why does Aaron Carter have so many Broadway credits?! We’ll never know. Here’s a fantastic article from the New York Times which talks about why Seussical took a nosedive when it came to Broadway. If you want to get a sense of where the Seussical creative team was emotionally at opening, have a look at this video... They love the laughter, they love the living, why are we talking about them in a Dr. Seuss episode? Who knows. But ‘The Moomins’ are a delight for all. Who knew there would be more than one Hallowe’en/Christmas mashup?! If you haven’t seen the fever dream that is the Kathy Najimy documentary on Dr. Seuss you REALLY need to. It seems to always come up when we chat Ahrens and Flaherty but what do you think about scaling back productions on Broadway? Is there too much pressure to go big budget? Let us know on Reddit! We are absolutely ecstatic to be working with The Broadway Podcast Network - the premiere digital destination for everyone, everywhere who loves theatre and the performing arts. If you haven’t had a chance yet, check out their website, follow them on socials and tell them we sent you! We have always been about nurturing a musical theatre community outside of Broadway and the West End so this will help so many more people hear our collective musical theatre nerd ‘YOPP!’ so give them your support! A Cursed Quiz Question Rumor has it that this musical is cursed. During out of town tryouts the lady’s bathroom in the theatre caught on fire, a dancer ran into the pit injuring a saxophonist who would die of a heart attack after being rushed to the hospital and the leading actor dropped dead in the wings during the second preview. What show?

Coping with your own grief when a spouse dies is hard enough. But what do you do when on top of that you need to raise a grieving family, get everyone to school on time, pay all the bills, and run the household all on your own? These are just some of the challenges widowed parents face. While grief professionals may offer helpful insights, our guest and psychologist Dr. Justin Yopp explains why peer support groups for widowed parents may be one of the most helpful resources for bereaved fathers and mothers. This episode is for widowed parents who are looking for inspiration and practical advice on parenting after loss. Based on insights gained by facilitating widowed parenting groups and academic research, Dr. Yopp offers compassionate guidance that respects each individual's journey. His book, The Group: Seven Widowed Fathers Reimagine Life, is based on the “Single Fathers Due to Cancer” project, a group facilitated by Dr. Yopp and his colleague Donald L. Rosenstein at the University of North Carolina. They now collaborate with other colleagues at UNC to run The Widowed Parent project, which is committed to supporting widowed mothers and fathers with children in the home. Proceeds from The Group are all donated back into the project in order to benefit the families. Learn More about Justin Yopp and the Widowed Parent Project: Widowed Parent Website Widowed Father's Facebook Page Widowed Parents on Twitter Widowed Parent Story on YouTube

“You're not alone. There are many, many people out there going through the same thing as you. You do not have to be perfect. You were not perfect before your husband or wife or partner died, and you don't need to be perfect now. Give yourself some leeway. Be self-forgiving, and be patient with yourself. You're going to drop a lot of balls. You're going to sometimes feel like it's overwhelming. You're going to feel like you're not sure you can do this, or you don't know how to move forward. You're going to have questions abound. Rely on your friends and family, even if they can't fully appreciate it. Give yourself some space; this takes time. There's no clock on this, no time limit.”  - Dr. Justin Yopp I had such a great discussion with Dr. Justin Yopp of the University of North Carolina for this episode. Justin is a clinical psychologist and is co-author of the book, “The Group: Seven Widowed Fathers Reimagine Life.” I really enjoyed our wide-ranging discussion. It was a fascinating mix of practical and academic, and included some great stories from the widowed dads in the book about their experiences. Some of the topics we covered include: the dual process model of coping and bereavement; post-traumatic growth; the concept of being a ‘good enough' parent; the unique hardships of being a widowed father; and the research into the needs of widowed parents being conducted at UNC. By the way, if you're a widowed mom or dad with kids 18 & under at home, and widowed less than three years, I'd encourage you to answer the survey on their web site…this is such important work and, surprisingly, there is very little research that's been done on the needs of widowed parents. Look for the link in the show notes for episode 9. I hope you enjoy my discussion with Dr. Justin Yopp.

Justin M. Yopp, Ph.D., is a clinical psychologist and Associate Professor of Psychiatry at the University of North Carolina. Dr. Yopp also co-leads the Widowed Parent program at UNC and […] The post Justin Yopp: Bereaved Dads: Making The Most of Mr. Mom appeared first on Open to Hope.

Episode 29: Field Recording #3: Yopp In Episode 29, Joey talks with listener-favorite, Yopp, about many things. Topics include knitting, blacksmithing, woodworking, magic mirrors, and fly fishing. This is the third field recording he made at UWC IX, back in June. Yopp was previously discussed on Episode 13: Magical Love Pants, and you should definitely hit up those show notes to see the magical love pants. Sponsors We are Knitcrate Ambassadors! Are you the kind of knitter who would enjoy receiving a surprise package of yarn in the mail every month? Then you need to sign up for a Knitcrate subscription. Every month, you will receive a selection of curated yarn, a pattern specifically paired to use with the yarn, and a treat. Use code KD20 at checkout for 20% off your first package when you sign up for a subscription. Special thanks to our sponsor: Coveted Yarn! Coveted Yarn is a local yarn shop in Gloucester, Massachusetts, and is an authorized dealer of our favorite knitting needles: Karbonz, by Knitter's Pride. In addition to a great variety of widely distributed yarn, Coveted Yarn offers their own signature line of yarn — Flat Rocks Yarn, which is dyed by the shop owner's sister. You can also find McPorter Farms knitting accessories and buttons at Coveted Yarn. World-wide shipping is available. Contact them via their website or at 1-978-282-8809 for more information and to place an order. Notes Misc Ukulele World Congress (UWC) — Joey had a great time again this year, and gathered several field recordings while he was there

March 6, 2016; Fourth Sunday in Lent; Mark 10:13-16   For the text of this sermon, go to www.unionuniversitychurch.org and select "Sermons-Text" from the menu.

Justin Yopp, PhD is a clinical psychologist at the University of North Carolina and is a member of the UNC Comprehensive Cancer Support Program. His clinical practice focuses on providing therapeutic services to both pediatric and adult patients with or affected by cancer.   In 2010, Dr. Yopp and his colleague, Dr. Don Rosenstein, developed a support program for widowed fathers who lost their wives to cancer. They currently run a support group for widowed fathers, are conducting research in the field, and have created an online resource of this population of widowers: www.singlefathersduetocancer.org  The Single Fathers Due to Cancer Program at UNC is dedicated to helping the tens of thousands of fathers who have lost their wives/partners to cancer and who are figuring out how to be an “only” parent to a grieving child. The program is first-of-its-kind in the United States and has a website offering resources, information and support to widowed fathers: http://singlefathersduetocancer.org. The site includes a series of short videos of widowed fathers discussing their experiences.

Die Pathogenität von enteropathogenen Yersinien-Spezies wird von einem Virulenzplasmid pYV kodiert. Das pYV kodiert für den Typ-III-Sekretions-/Translokationsapparat und die Yops. Sechs Yop-Effektorproteine sind bekannt, die in die eukaryote Zelle transloziert werden: YopE, YopH, YopM,YopO/ YpkA, YopP/ YopJ und YopT. Die intrazellulären Angriffspunkte und Wirkungen der einzelnen Yops auf die Zielzelle sind Gegenstand aktueller Forschung. In dieser Arbeit wurden erstmals systematisch potentielle Zytoskelettveränderungen von Thrombozyten durch Inkubation mit Yersinia-Monosekretionsmutanten YopH, YopE, YopO, YopP, YopM und den Yersinia-Monodeletionsmutanten DeltaYopH, DeltaYopE, DeltaYopT, DeltaYopO und DeltaYopM untersucht. Im zeitlichen Verlauf adhärieren uninfizierte Thrombozyten durch eine Zunahme der Fläche durch Ausbildung von Filopodien und Lamellipodien. In den durchgeführten Experimenten ähneln die mit der YopP-Monosekretionsmutante inkubierten Thrombozyten uninfizierten Thrombozyten, d.h. YopP zeigt als Einziges der untersuchtes Yops keinen Einfluss auf das Zytoskelett. Mit der YopH, YopM, YopE bzw. YopO-Monosekretionsmutante inkubierte Thrombozyten zeigen kleinere Zellflächen und eine Dominanz von abgerundeten Zellen. Dies deutet auf eine schlechtere Adhäsion der Zellen an der extrazellulären Matrix hin. In mit WA-C(pTRANS,pCJYM-HA) infizierten HeLa-Zellen konnte YopM zunächst im Zytosol, nach 2-4h Infektion zusätzlich im Zellkern lokalisiert werden. Ausserdem zeigten mit WAC(pTRANS,pCJYM-HA) infizierte HeLa-Zellen Zytoskelettveränderungen: ein ungeordnetes Zytoskelett mit Vakuolen, vereinbar mit einer Ablösung der Zelle von der Matrix. Kaya et al. konnten im Affinitätsblot in vitro eine Interaktion von YopM mit der intrazellulären Cystein-Protease Calpain zeigen. Wegen der morphologischen Ähnlichkeit zwischen mit WA-C(pTRANS,pCJYM) inkubierten bzw. mit Calpeptin, einem Calpain-Inhibitor, inkubierten Thrombozyten wurde die von Kaya et al. dargestellte Interaktion zwischen YopM und Calpain in vivo in dieser Arbeit überprüft. Die Präzipitationsversuche aus infizierten HeLa-Zellen über Calpain sowie über YopM ergaben keinen Hinweis auf eine Interaktion von YopM und Calpain. McDonald et al. publizierten RSK 1 und PRK 2 als intrazelluläre Interaktionspartner von YopM. Funktionelle Studien über die Proteine RSK 1 und PRK 2 lassen darauf schließen, dass sie regulierende Einflüsse auf das Zytoskelett, die Translation und das Zellüberleben haben. Diese Funktionen und die beobachteten Einflüsse von YopM auf das Zytoskelett der Zielzelle sind mit einem Modell vereinbar, in dem YopM die Zytoskelettveränderungen durch Interaktion mit RSK 1 und PRK 2 hervorrufen könnte. Diese Hypothese muss durch zukünftige Forschungen geklärt werden.

Die Exposition von Makrophagen gegenüber Bakterien oder LPS führt über die Aktivierung zellulärer Signalkaskaden zu einer vermehrten Expression von Genen, deren Proteinprodukte zelluläres Überleben unter Infektionsbedingungen ermöglichen. Die Aktivierung des Transkriptionsfaktors NF - kB spielt dabei eine wichtige Rolle. Pathogene Yersinia enterocolitica - Stämme hemmen die Aktivierung von NF - kB und induzieren Apoptose bei Makrophagen. In dieser Arbeit konnte gezeigt werden, dass das Yersinia - Effektorprotein YopP maßgeblich an der Apoptoseinduktion beteiligt ist. Bei Infektionsversuchen konnten lediglich die Yersinienstämme bei Makrophagen Apoptose induzieren, die über einen funktionstüchtigen Typ III - Sekretionsapparat und ein dadurch transloziertes YopP verfügen. Eine transiente Überexpression der transkriptionell aktiven NF - kB - Untereinheit p65 schützt Makrophagen spezifisch vor durch Yersinien, nicht jedoch vor durch Salmonellen induzierter Apoptose. Das weist darauf hin, dass YopP durch die Blockierung des NF - kB aktivierenden Signalwegs Apoptose bei Makrophagen vermittelt. Die Transfektion von J774A.1 Makrophagen mit YopP induzierte bei 40 - 50% der transfizierten Zellen Apoptose. Durch die zusätzliche Stimulation mit LPS konnte die Apoptoserate auf 80 - 90% gesteigert werde. Dieser synergistische, proapoptotische Effekt ist direkt auf durch LPS induzierte Signaltransduktions -prozesse zurückzuführen. Aus Transfektionsversuchen mit dominant - negativen Signalmolekülen der TLR - Signalkaskade ergaben sich Hinweise auf eine Beteiligung der Transmitter MyD88 und IRAK2 an der Apoptoseeinleitung. IRAK1 und TRAF6 scheinen dagegen eher ein antagonistisches, NF - kB aktivierendes LPS - Signal zu bedienen, welches unter dem Einfluss von YopP unterdrückt wird. Dadurch überwiegt das durch LPS induzierte, proapoptotische Signal, welches den apoptotischen Zelltod einleitet. Die Aktivierung des Apoptoseprogramms selbst erfolgt über FADD und Caspase - 8.

Die Pathogenität von Y. enterocolitica O:8 ist gekoppelt an das Vorhandensein des 70 kb großen Virulenzplasmides (pYV), das für die Gene eines Typ-III-Sekretionssystems kodiert und die Translokation von 6 Yop Effektorproteinen (YopE, YopH, YopM, YopO, YopP und YopT) in das Zytosol eukaryontischer Zellen ermöglicht. Intrazellulär interagieren Yop Proteine dabei mit verschiedenen Zellstrukturen und Signaltransduktionskaskaden, wodurch es zu einer Modulation der Immunantwort im Wirtsorganismus kommt. Durch systematische Mutagenese der yop-Gene und Untersuchung der yop Deletionsmutanten im Mausinfektionsmodell konnte in dieser Arbeit ein Einfluss der Yop Proteine auf die Virulenz und die Auslösung einer Immunantwort nachgewiesen werden. Die Translokation eines heterologen Antigens (YopE/LLO) durch das Typ-III-Sekretionssystem führte zur Induktion einer spezifischen CD4 und CD8 T-Zellantwort gegen Listeriolysin O (LLO) und ermöglichte die Verwendung von Y. enterocolitica als oralen Lebendimpfstoff zur Immunisierung gegen eine Listeria monocytogenes Wildtyp Infektion.

Yersinien sind auf Grund ihres spezifischen Typ III-Proteinsekretionssystems (TTSS) in der Lage, nach Anlagerung an Zellen bakterielle Virulenzproteine in das Innere der Wirtszelle zu translozieren. Dies führt zu einer Zellparalyse und bei Makrophagen zum Zelltod. Eines der translozierten Virulenzproteine ist YopP/J, das die Signalwege der mitogenaktivierten Proteinkinasen (MAPK) sowie des Transkriptionsfaktors NF-kB in der Wirtszelle inhibiert. Es wird angenommen, dass YopP/J zur Familie der Cystein-Proteasen zählt. Es zeigt Homologien zu AvrRXV/AvrBst von Xanthomonas campestris, welches eine dem apoptotischen Zelltod vergleichbare sogenannte „Hypersensitive Reaktion (HR)“ bei Pflanzen auslösen kann. Die Bakterien der enteropathogenen Spezies Yersinia enterocolitica, welche nach oraler Aufnahme im terminalen Ileum durch M-Zellen in die Lymphfollikel der Peyerschen Plagues wandern, werden anhand ihrer Oberflächen-(O)- und Geißel-(H)-Antigene in verschiedene Serotypen unterteilt. Unsere Studien haben gezeigt, dass sich einzelne Y. enterocolitica-Serotypen in der Apoptoseinduktion bei Makrophagen unterscheiden. In der vorliegenden Arbeit wurde den Mechanismen der Apoptoseinduktion durch die verschiedenen Y. enterocolitica-Serotypen nachgegangen. Zunächst konnte YopP für die unterschiedlichen Apoptose-Effekte verantwortlich gemacht werden. Durch DNA-Austausch und der anschließenden Modifikation einzelner Aminosäuren zwischen YopP von Y. enterocolitica-Serotyp O8 und Y. enterocolitica-Serotyp O9 konnte Arginin (R) an Position 143 als essentielle AS der Effektordomäne von YopPO8 definiert werden. YopP von Y. enterocolitica-Serotyp O9 und Y. enterocolitica-Serotyp O3 besitzt an dieser AS-Position Serin (S). YopPO8 vermittelt deutlich stärker Apoptose als YopPO9 und YopPO3. Der erhöhten Apoptoseinduktion durch YopPO8 geht eine effiziente Unterdrückung der NF-kB-Aktivierung vorraus. Die Inhibition des antiapoptotischen NF-kB-Signalwegs durch YopP scheint Voraussetzung für die Apoptoseinduktion durch Yersinia zu sein. Des weiteren wurde in dieser Arbeit mit Hilfe des Hefe-2-Hybrid-Systems nach neuen unbekannten intrazellulären YopP-Interaktionspartner gesucht. Aus einer Maus-Milz-cDNA-Genbank konnten 22 potentielle YopP-Interaktionspartner isoliert werden. In in vitro-Bindungsstudien konnte bis zum jetzigen Zeitpunkt eine Interaktion von YopP mit vier Proteinen (PP2Ac, FWD2, eEf1bb, Smad1) bestätigt werden. Weiterführende Bindungs- und Funktionsanalysen werden noch durchgeführt. Die möglichen Auswirkungen dieser Interaktionen werden diskutiert. Die durchgeführten Studien erbrachten zudem Hinweise auf eine Modifikation von YopP in der Wirtszelle. Darüberhinaus konnte mit Hilfe des Hefe-2-Hybrid-Systems der Interaktionsbereich von YopP mit seinem Zielprotein IKKb eingeschränkt werden. Die durchgeführten Bindungsanalysen mit IKKb-Deletionsmutationen weisen auf eine Bindung von YopP an den IKKb-N-Terminus hin. Das Ergebniss wurde durch in vitro-Bindungsstudien bestätigt. Unter anderem scheint Alanin an IKKb-Position 120 die Interaktion mit YopP zu bestimmen. So konnten im Rahmen dieser Doktorarbeit unterschiedliche Aspekte der Wechselwirkung von Y. enterocolitica YopP mit der Wirtszelle und Wirtszellproteinen analysiert werden. Diese Studien tragen zum besseren Verständnis der Immunmodulation durch pathogene Bakterien bei.