Podcasts about arachidonic

In this penultimate instalment on our dairy series, I'm going to cover the effects of dairy on pain, and what to be aware of when managing endo. And yes - it's not straight forward! In our first episode on dairy and endo, we discussed A1 casein, but for those who haven't listened to that episode, let's cover it again. A1 casein is a type of milk protein which research suggests some people find triggers intestinal inflammation and gut issues. The data on humans is emerging, and whilst it's true for a number of people, not everyone will have this inflammatory reaction to A1 casein. However, if you do experience inflammatory reactions to A1 casein, this can trigger a systemic full body inflammatory response with regular exposure, in a few ways. Read more. Shownotes A1 casein https://pmc.ncbi.nlm.nih.gov/articles/PMC5593102/ https://www.youtube.com/watch?v=JirAKjC_Kh0 https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2024.1501596/full https://pmc.ncbi.nlm.nih.gov/articles/PMC7033038/ https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2024.1363455/full https://pmc.ncbi.nlm.nih.gov/articles/PMC5593102/ https://www.tandfonline.com/doi/10.3109/09513590.2011.588753 https://www.clinsurggroup.us/articles/JGRO-10-226.pdf https://pubmed.ncbi.nlm.nih.gov/6790261/ https://pubmed.ncbi.nlm.nih.gov/3488529 https://www.sciencedirect.com/science/article/abs/pii/S1130862119303158 https://www.sciencedirect.com/science/article/pii/S0021925818953226 https://www.sciencedirect.com/science/article/pii/S0015028206014373 https://pmc.ncbi.nlm.nih.gov/articles/PMC9396281 Lactose https://www.theendobellycoach.com/podcast/endo-belly-dairy https://pmc.ncbi.nlm.nih.gov/articles/PMC2835780/ https://pmc.ncbi.nlm.nih.gov/articles/PMC9101724/ https://academic.oup.com/rheumatology/article-abstract/47/8/1223/1785625 https://www.jacionline.org/article/0091-6749(91)90180-V/pdf https://onlinelibrary.wiley.com/doi/full/10.1111/apt.12306 https://pmc.ncbi.nlm.nih.gov/articles/PMC9101724/ Histamines https://www.sciencedirect.com/science/article/pii/S0021925818953226 https://www.sciencedirect.com/science/article/pii/S0015028206014373 https://pmc.ncbi.nlm.nih.gov/articles/PMC9396281 https://my.clevelandclinic.org/health/articles/24854-histamine https://integrativewomenshealthinstitute.com/histamine-intolerance-autoimmunity-and-endometriosis/ Arachidonic acid https://lipidworld.biomedcentral.com/articles/10.1186/s12944-019-1039-y https://pubmed.ncbi.nlm.nih.gov/29610056/ https://www.mdpi.com/2075-1729/13/3/654 https://www.clinsurggroup.us/articles/JGRO-10-226.pdf Free resources: This podcast!  Endometriosis Net Column Endometriosis News Column Newsletter Instagram Email me: hello@theendobellycoach.com Ways to work with me: This EndoLife, It Starts with Breakfast digital cookbook Masterclasses in endo nutrition, surgery prep and recovery and pain relief Live and Thrive with Endo: The Foundations DIY course One to one coaching info and application This episode is sponsored by BeYou Cramp Relief Patches. Soothe period cramps the natural way with these 100% natural and discreet menthol and eucalyptus oil stick on patches. Click here to find out more and to shop: https://beyouonline.co.uk/pages/how-it-works Produced by Chris Robson

Humans have had an insatiable appetite for inhibiting production of prostaglandins for centuries! This series delves into the history of aspirin and NSAIDs, looking at the understanding of the prostaglandin pathway. ·       Intro 0:12 ·       In this episode 0:23 ·       What are NSAIDs? 0:53 ·       Prostaglandins 5:50 ·       What are prostaglandins? 7:19 ·       Where do prostaglandins come from? 8:45 ·       So, what do we do with prostaglandins? 13:15 ·       How did they figure out prostaglandins? 13:55 ·       Naming the prostaglandin 21:25 ·       Phospholipids 24:46 ·       Arachidonic acid 25:28 ·       Arachidonic acid into prostaglandins: how do you prove it? 26:32 ·       How does arachidonic acid turn into prostaglandins? 27:27 ·       Cyclo-oxygenase 28:36 ·       mRNA and COX-2 32:50 ·       On the next episode 35:55 ·       Summary 36:38 ·       Thanks for listening 37:49 Disclosures: Brown reports no relevant financial disclosures. We'd love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum. References: Botting RM. Pharmacol Rep. 2010;doi:10.1016/s1734-1140(10)70308-x. Flower RJ. Br J Pharmacol. 2006;doi:10.1038/sj.bjp.0706506. Flower RJ. Br J Pharmacol. 2019;doi:10.1111/bph.14588. Kurzrok R, et al. Exp Biol Med. 1930;doi:10.3181/00379727-28-5265. https://www.nobelprize.org/prizes/medicine/1970/euler/biographical/. von Euler US. J Physiol. 1936;doi:10.1113/jphysiol.1936.sp003433.

Any Purchase of Equi Life products through my affiliate links supports you and the mission to spread true health empowerment: https://equi.life?irad=908976&irmp=2507476 Sources: https://stephencabral.com/podcast/1348/ To Schedule a free Health Conversation Visit: rootlvlwellness.com or email me at mathew@rootlvlwellness.com (1) Sedentary lifestyle, lack of blood flow 2) Too much caffeine, reduces the size of the brain (3) Excess alcohol, get to grow bad bacteria in the gut (4) Nicotine (5) Processed sugar (6) A 2003 study showed a high saturated diet doubled the risk for Alzheimer's. Keep your level of Arachidonic acid low, AA is highly inflammatory. You can test your level with an Omega 3 test. Bonus 1) A high vegetable diet lowered risk of Alzheimer's & cognitive decline by 35% Take a FREE Toxicity Assessment or Thyroid Assessment: https://stephencabral.com/assessments/?x=matdiaz&c=6ec01bcd Recommended Resources: https://stephencabral.com/resources/?x=matdiaz&c=6ec01bcd If you don't own your Health who does? Make sure to Like, Comment, and Subscribe and share with anyone who you feel it could serve. Follow Me On IG @mathewthehealthcoach --- Send in a voice message: https://anchor.fm/mathew-diaz/message

https://bengreenfieldfitness.com/fishoilpodcast After publishing my recent giant fish oil article , I've been getting plenty of questions about fish oil lately, including: -Based on human clinical research, what are the actual proven benefits of fish oil? -What kind of dosages/types of fish oil were used in studies? -Are there concerns about rancidity/oxidation when taking fish oil? -What kind of amount and EPA/DHA ratio is ideal? -Are there people who shouldn't take fish oil? -Are there certain nutrients or supplements that should be taken with fish oil? -How can one test their omega fatty acid status? And much more. So I finally decided to get a couple of true, unbiased fish oil experts on my show. is my first guest. He is an internationally recognized expert on omega-3 fatty acids and how they can benefit patients with heart disease. He obtained his Ph.D. in Human Nutrition from the University of Minnesota and did post-doctoral fellowships in Clinical Nutrition and Lipid Metabolism with Dr. Bill Connor at the Oregon Health Sciences University. His interest in omega-3 fatty acids began with his postdoctoral work when he published his first study on the effects of salmon oil on serum lipids in humans (1980). Since that time he has been the recipient of five NIH grants for studies on the effects of omega-3 fatty acids (EPA and DHA) on human health. He has more than 300 publications relating to fatty acids, including omega-3s, in medical literature and was an author on two American Heart Association scientific statements on fatty acids: “, and “ both published in the journal Circulation. Dr. Harris is a Professor in the Department of Medicine in the Sanford School of Medicine at the University of South Dakota and the President and CEO of OmegaQuant. Dr. Harris's daughter, , PhD, RD is my second guest. Kristina received her PhD in Nutritional Sciences from Pennsylvania State University in 2013 and completed her training to become a Registered Dietitian in 2014. As a graduate student, she studied under Dr. Penny Kris-Etherton, an internationally-recognized expert in fats and nutrition. She worked as a postdoctoral fellow at the University of Colorado-Denver under Dr. John Peters in the area of worksite wellness before returning to the omega-3 field. Kristina joined the family business Analytics as a Research Associate in 2014, with a particular focus on omega-3s in maternal health, helping create the Prenatal DHA test and the Mother’s Milk DHA test. In 2020, she became Assistant Professor (non-tenure) in the Department of Internal Medicine at the University of South Dakota Sanford School of Medicine. (2020-2022). She lives in Sioux Falls, South Dakota with her husband, two kids, one old dog, and four grandparents. During this discussion, you'll discover: -The 2 sources of Omega-3 fatty acids...8:35 Plant derived fatty acid ALA, alpha linolenic acid( 18 carbons); an acid in the omega-3 family – not the same thing as the fish derived omega-3 Fish derived EPA (20 carbons) and DHA (22 carbons) Cannot get much of the good stuff from ALA (seeds and nuts) Algal oil from micro algae (single cell organism, not kelp) that make EPA/DHA naturally; at the base of the marine food chain Omega-3 fatty acids are made by plants, not fish Some companies grow these algae in big ponds, harvest the omega-3 fatty acids and put in capsules Vegan derived EPA/DHA products has exactly the same molecules as EPA/DHA derived from fish, but does not come from fish, it comes from algae Process is expensive Aquaculture industry is driving the demand for algal oil 70~80% of fish oil produced is fed back to the fish Other sources of fish oil are genetically modified land plants Canela seed oil; Australia is at the forefront to put genes into oil producing land plants, like soy beans -What makes essential fatty acids so essential...15:45 Cell membranes, made up of fatty acids, surround every cell in the body For structural aspect of the cell Provides starting products for different signaling pathways, affects how cells communicate internally and externally Membrane fluidity; more carbon and double bonds makes cell membranes more flexible and fluid Cell membranes are comprised of dietary fats The body can’t make the essential omega-6 fatty acids (linoleic) and omega-3 fatty acids(ALA and EPA/DHA); these comes from the diet Trans-fats are also dietary fats Other fats, like saturated fats and monounsaturated fats, are affected by metabolism -Omega-3 fatty acids being oxidized once it enters the body is a misconception...19:36 Oxidation has different meanings to a biochemist and a food scientist: Oxygen molecules are added to the fatty acids by enzymes in order to be activated Lipid peroxidation destroys, produces unwanted by-products; does not happen inside the body because of the different anti-oxidants that protect against this type of oxidation Article: The body has ways of cleaning up things it doesn’t want -Ratio of omega fatty-acids in the body and what the ratios should be...25:32 Good ratio of EPA to DHA is when eaten in fish EPA taken alone increases EPA and decreases DHA a little bit; increased omega-3 index - the measure of EPA/DHA in red blood cells (RBC) Pure DHA taken alone increases both EPA and DHA in RBC DHA is the predominant omega-3 fatty acid in membranes 85% DHA to 15% EPA in RBC In fish oil, total dose (EPA+DHA) is the important thing A study found the ideal optimum fatty acid levels (EPA+DHA) to be 8~12% index Ratio of omega-6 to omega-3 -Ethyl Ester and Triglyceride forms of Omega-3 fatty acids...33:20 Different ways Omega-3 fatty acids are processed and concentrated Ethyl ester is the first highly concentrated form; first to be concentrated into a capsule Triglycerides form is the more natural form (how it would be present in the fish) Most fish oil supplements in the U.S., if it does not say it is in triglyceride form, is an ethyl ester No standardized way to know if it is triglycerides or ethyl ester Biggest difference as far as bioavailability goes is if supplements are taken with meals Ethyl esters, if taken without a meal might not be absorbed at all; absorbed well if taken with a meal, preferably a meal that contains fats Triglycerides are not affected by that meal component as ethyl esters All pharmaceutical brands of fish oil are ethyl esters More EPA and DHA molecules in a 1 gram capsule if in ethyl ester form Distinction only came up around 15 years ago when ethyl ester form of fatty acids was seen as not well absorbed by the body when taken on an empty stomach Taking ethyl ester form supplements without food might not get the desired omega-3 index result -What genes convert ALA or plant-based oil into EPA/DHA...45:15 Genetic conditions that affect omega-3 fatty acid levels FADS genes produce the enzymes that convert ALA to EPA and DHA Enzymes also convert linoleic acid to arachidonic acid (polyunsaturated omega-6 fatty acid) Natural variations by populations in the kinds of mutations that are present in the FADS genes can affect levels, particularly of arachidonic acid Omega-3 EPA/DHA are not much affected by the FADS genes Major genetic effect driving omega-3 levels in the population is not known Is there a genetic effect on the absorption of omega-3 in the population? No study on why a certain population has a huge absorption response while in another population, there is hardly any response Nomenclature: Omega-3 ­– a fatty acid where the 1ˢᵗ double bond counting from the omega carbon is in the third position Omega-6 – a fatty acid where the 1ˢᵗ double bond counting from the omega carbon is in the sixth position Cannot be inter-converted Plants can convert omega-6’s into omega-3’s, animals cannot -Ratio of omega-6 to omega-3 fatty acids...52:17 “Ratio of omega-6 to omega-3” is imprecise – it’s not clear what type omega-6 or omega-3 is referred to; for example, there are 7 omega-6 fatty acids in the blood It also presumes that ALA and EPA/DHA have the same biologic activity or they have the same value when they do not The same is also true on the omega-6 side To say “total omega-6 to total omega-3 ratio” would also be confusing; it does not say what type fatty acids are there; it does not tell anything about it's effect on health - some fatty acids are beneficial and some are not You can have very high levels of omega-6 and omega-3 in your blood, or you can have very low levels, and yet have the same ratio It also presumes that all omega-6’s are bad and all omega-3’s are good, which is not true Omega-3 fatty acids being good is not questionable What’s questionable is the goodness or badness of omega-6’s; linoleic acid is not made in the body and has to be eaten Studies have shown that high levels of linoleic acid in the blood always predict lower incidence of heart disease and diabetes, and conversely Focus on the omega-3 index is that EPA/DHA are what is missing in our diets; there are plenty of omega-6’s -Link between Omega-6 and inflammation and chronic disease...1:00:18 High consumption of oxidized PUFAs , primarily found in vegetable oils which are high in omega-6 fatty acids Omega-6 fatty acid that gives rise to eicosanoids in the inflammatory pathway is Arachidonic acid, a synthetic product of linoleic acid Eicosanoids is associated with increased incidence of inflammation and chronic diseases like arthritis, cancer, etc. Synthesis of arachidonic acid is very regulated; tissue levels remain the same regardless the amount of linoleic acid consumed, to a point (it eventually runs out if linoleic acid consumption is stopped) Higher levels of linoleic acid in the blood means you are eating more of it, which comes from vegetable oil; the only way to get high levels in your blood is to eat more For heart disease and diabetes, higher levels of linoleic acid is good for the heart and metabolism; less people develop these diseases if they have high levels of linoleic acid The best way to decrease the ratio is to increase your omega-3 side; by increasing EPA/DHA, EPA replaces, to some extent, the arachidonic acid Having more long-chain omega-3 in the membranes lowers omega-6, correcting the proportion -Contaminants in fish oil, cleanliness, sourcing, concerns about packaging, shelf life, heat exposure during the manufacturing process...1:06:13 Article: Adding anti-oxidants makes a lot of sense Nitrogen blanketed environment during encapsulation Fish oil “gone rancid” does not necessarily mean the omega-3 fatty acids are gone, it just smells bad; the bad smell is caused by any of 6 molecules The best way to know the fish oil supplements are working for you is by testing -And much more! Resources from this episode: - - (use code BGF20 to save 20%) -Articles: Episode sponsors: -: If you're ready to upgrade your fish oil, head over to and grab Kion Omega. Use code BGF20 to save 20% off your first order. -: Enjoy all the benefits of the 11 superfoods and their micronutrients that help increase resting metabolism, support cardiovascular health, and remove toxins to turn back the hands of time! Receive a 20% discount on your entire order when you use discount code BENG20. -: I’ve been using Four Sigmatic products for awhile now and I’m impressed by the efficacies of their mushroom products. I use them. I like them. I support the mission! Receive 15% off your Four Sigmatic purchase when you use discount code BENGREENFIELD. -: Organic brands you love, for less. Your favorite organic food and products. Fast and free shipping to your doorstep. Receive a gift card worth up to $20 when you begin a new membership. Do you have questions, thoughts or feedback for Dr. Harris or me? Leave your comments below and one of us will reply!

Omega-3 or fish oil supplements are popular right now. Folks take these in an effort to achieve the right balance of omega-3 and omega-6 essential fatty acids. It's true that for optimal health, we really need to optimize the ratio of these essential fatty acids. The right balance can protect our heart health, reduce inflammation in the body and improve neurological function. But how do we get there? Are supplements the best way to get these essential fatty acids? How can we get more omega-3 fatty acids in our diet? Is it possible to get too much omega-3? Is omega-6 all bad? Sally Fallon Morell, the head of the Weston A. Price Foundation, dispels myths and misconceptions about essential fatty acids in this episode, as she explains principle 8 of the Wise Traditions diet: how traditional peoples ate just the right balance of omega-3 and omega-6 fatty acids. (These fatty acids are called essential, by the way, because we must get them from our diet. Our bodies can’t make these on their own.) She covers the importance of arachidonic acid, the role of DHA and EPA, and the ideal ratios of omega-3 and omega-6 fatty acids. Most importantly, she discusses which foods to include in the diet to strike the delicate balance that is critical for improved health and wellbeing. See Sally's blog at nourishingtraditions.com Check out our sponsors: Ancestral Supplements and North Star Bison Find more resources on our website: westonaprice.org Register for our conference at wisetraditions.org 

Here are 3 ways to clear stubborn inflammation: managing your fatty acids, taking a new supplement that jump-starts the resolution process, or going with the aspirin protocol from a few episodes ago. Tune in for the details! This episode is brought to you by Ancestral Supplements' "Living" Collagen. Our Native American ancestors believed that eating the organs from a healthy animal would support the health of the corresponding organ of the individual. Ancestral Supplements has a nose-to-tail product line of grass-fed liver, organs, "living" collagen, bone marrow and more... in the convenience of a capsule. For more information or to buy any of their products, go to https://chrismasterjohnphd.com/ancestral This episode is brought to you by Ample. Ample is a meal-in-a-bottle that takes a total of two minutes to prepare, consume, and clean up. It provides the right balance of nutrients needed for a single meal, all from a blend of natural ingredients. Ample is available in original, vegan, and keto versions, portioned as either 400 or 600 calories per meal. I'm an advisor to Ample, and I use it to save time when I'm working on major projects on a tight schedule. Head to https://amplemeal.com and enter the promo code “CHRIS15” at checkout for a 15% discount off your first order.” To get these episodes free of ads, with transcripts, and weeks or sometimes even months before they are released to the public, along with access to monthly live Q&A sessions, sign up for the CMJ Masterpass at https://chrismasterjohnphd.com/masterpass. Use the code LITE10 to get 10% off. To make it easier to get the discount, use this link, which has the coupon already activated: https://masterpass.chrismasterjohnphd.com/cmj-masterpass/2200/buy?coupon=LITE10 Here are links mentioned in this episode: The last episode on omega-6 and omega-3 fatty acids:   https://chrismasterjohnphd.com/2019/01/08/omega-6-omega-3-fatty-acid-ratio-care/ The aspirin episode: https://chrismasterjohnphd.com/2019/01/01/aspirin-goes-best-bicarbonate-glycine/ Here are products mentioned in this episode. Purchasing them using these links earns me a small commission at no extra cost to you, which helps support the free work I provide: Arachidonic acid supplements: https://chrismasterjohnphd.com/aa Specialized pro-resolving mediators: https://chrismasterjohnphd.com/spm

Because we’ve demonized the use of anabolics for cosmetic purposes, there’s a lot of it being sold on the black market— much of which isn’t legitimate. What are some of the worst compounds to take from an unreliable source? Why is arachidonic acid such an important nutrient for performance? On this episode, I’m joined by author, scientist and anabolics expert, Bill Llewellyn, to discuss these questions and more. Aside from protein, arachidonic acid is the most important nutrient in training and performance. -Bill Llewellyn     Three Takeaways Only ⅓ of the anabolic products sold on the gray market are actually legitimate. Testosterone cypionate vs. testosterone enanthate when it comes to legitimacy: 35% of cypionate samples were legit while enanthate was legitimate over 70% of the time. Arachidonic acid is a natural anabolic. It can help facilitate growth and muscle recovery, and it can help you break through plateaus. At the start of the show, Bill talked about how he got started and why the demonization of anabolic steroids is a farce. Next, we talked about the work Bill’s company is doing in creating a test for growth hormone. We also talked about what percentage of the compounds on the market are actually legit.   We also discussed; The best compounds according to label claim How hard it is to tell the difference between the real stuff and the fake stuff The power of supplementing arachidonic acid The medicinal, life-enhancing and restorative qualities of anabolics and testosterone are incredible. Yet in order for patients to see these benefits, they need to be getting legitimate products in the first place. That’s why it’s so important to educate people on the right products and how to get them through legitimate channels to avoid harm or wasting money on glorified placebos.   Guest Bio- Bill is an author and scientist in the field of human performance enhancement. He is also the founder of Molecular Nutrition. His books include the Anabolics Book and the Sports Supplements Reference Guide. Find him on Facebook https://www.facebook.com/AuthorWL/.

“How can I optimize my health and longevity?” “How can I live a long time and feel good doing it?” “What supplements should I take for peak performance?” “What should my ideal diet look like?” Honestly, without any data about your blood and biomarkers, you have no idea. This is because unless you know what your blood looks like under a microscope, there is no way for you to identify with 100% confidence what steps you should take to eat the right diet, to take the right supplements, to protect your health, to enhance your well-being, to perform at peak capacity, and perhaps most importantly, to live as long as possible with as high a quality of life as possible. Enter blood testing. Blood testing is the most important step you can take to identify and prevent life-threatening diseases before they happen to you. With your blood test results in hand, you can catch critical issues in your body before they manifest as heart disease, cancer, diabetes, or worse. Knowledge of exactly what is going on inside your body empowers you to implement a science-based disease-prevention program that can literally add decades of healthy years to your life. And if your goal is to not only stop disease, but to also perform at your peak physical and cognitive capacity, blood testing is absolutely crucial for identifying which diet, which supplements and which lifestyle steps you should take to optimize your specific and unique health parameters. But sadly, most annual medical check-ups that the average physician orders are simply routine, old-school blood tests that don't even test for the most important markers of disease risk, and that are simply designed to make sure you're “not dying”. They aren't designed to optimize longevity or to ensure your body is completely primed to perform at peak capacity. What most people don't realize is that you can skip your physician and simply manage the entire process for getting your blood work done yourself. And if you want to test absolutely every little thing that affects your organs, your energy, your hormones, your health and your longevity, then you've found the ultimate answer. I worked closely with WellnessFX, America's top laboratory for concierge blood testing and online access to all your blood testing results, to develop the and , which is the most complete blood testing package for men that money can buy.  This is by far the most comprehensive blood testing package I recommend and is designed for the high performer, biohacker or anti-aging enthusiast who wants access to the same type of executive health panel and screening that would normally cost tens of thousands of dollars at a longevity institute. The panel I discuss in today's podcast dives deep into overall metabolic functioning for optimal long-term health and longevity, and includes thyroid function, stress response, blood glucose regulation, sex hormone balance, heavy metals, inflammation, organs of detoxification (liver, kidneys, gallbladder, and lungs), proteins, electrolytes, blood oxygen and nutrient delivery, immune system status, vitamin D status and much, much more, including: 25-Hydroxy-Vitamin D Apolipoprotein A-1 Apolipoprotein B Blood Lead Blood Mercury Cardio IQ Lipoprotein Fractionation Ion Mobility Complete Blood Count w/ differential Complete Metabolic Panel Copper Cortisol Dehydroepiandrosterone Sulfate Ferritin, serum Fibrinogen Folate Free Fatty Acids Hemoglobin A1c Homocysteine High-sensitivity C-reactive protein IGF-1 (Growth hormone surrogate) Insulin Iron, TIBC Lipid Panel Lipoprotein (a) Luteinizing Hormone Omega 3 Fatty Acids RBC Magnesium Reverse T-3 Selenium SHBG (sex hormone binding globulin) T-3 Total T-3 Uptake T-4 (Thyroxine) T-3 Free T-4 Free Testosterone + Free Testosterone Thiamine Thyroglobulin Antibodies Thyroid Peroxidase AB TSH Uric Acid Vitamin A Vitamin B12 Zinc Estradiol As you can see, I've held nothing back and covered all bases with this customized blood panel. You will not find a test this comprehensive anywhere else, guaranteed. From identifying disease to optimizing longevity and anti-aging to maximizing performance, this test gives you absolutely everything you need. During this podcast, in which I cover my own results from my recent longevity panel, you'll discover: My own process of testing my blood. I had 19 tubes of blood drawn; you typically have 3-5 tubes drawn in a blood test. My motivation: What if you want the same type of blood test that would be tens of thousands of dollars at a longevity center? I wanted to advise myself with more precision than typical blood tests such as TSH. I designed a package with Wellness FX, for men and women. I do this on a quarterly basis; although once a year (or once per life) is sufficient for most people. First thing you see on the report: cardiovascular health. Basic lipid panel. Risk factors: Red (high caution); orange (pay attention); green (good to go). A lot of red doesn't necessarily mean a bad thing; all green doesn't necessarily mean all good either. My total cholesterol is red: 267. High cholesterol isn't a risk factor; it's when it becomes oxidized. My HDL levels are through the roof: 151. High level of HDL could mean your body is carrying a lot of metabolites to the liver due to constant inflammation. I tested all my inflammations, all very low. Question to ask: are you a lean mass hyper responder? Could have a higher LDLP particle count. High HDL, inflammation is low, not of concern. High cholesterol and high inflammation, be concerned. Below lipid panel you'll see LDL particles. I use the Thorne multivitamin. The chlorogenic acid you find in artichoke extract is efficacious in lowering APOB My peak LDL size has been climbing; ideally I want it above 222 1/2. My LDL particle count is actually low. Small low density lipoprotein low compared to peak LDL size. Overall I'm happy with my results. Look for increase in the size of my LDL particles. “How can I live a long time and feel good doing it?” Free fatty acids associated with diabetes and heart disease. Omega Index: two different fatty acids in your red blood cells. Arachidonic acid levels are normal; I feel like I could step up my Omega 6 fatty acid intake. (Sprinkle hemp seeds on your salad.) Metabolic health: Risk factors for diabetes and insulin resistance. You want your insulin levels relatively low. Wellness FX will give suggestions on how to lower insulin levels. My blood glucose level wasn't concerning, but a bit higher than normal. Homa IR score: Takes both glucose and insulin levels into account. A ratio of glucose vs. insulin. Thyroid health: You typically see only TSH. Mine has much more... My antibodies to thyroid are very low. Reverse T3 is very low; not concerned about stress. Free thyroxin index is normal. Thyroid peroxidase is a target of antibodies. I have low T3, T4, both total and free. My natural weight is 190-195; my actual weight is 175. I rarely eat until I'm full. Metabolic hormones: IGF is a bit low; I'll take colostrum for this. Cortisol: It's at 24; I want it between 2-20. If it's elevated on one snapshot, consider testing again. Cortisol metabolites. Dutch test for hormones. (link needed) Liver and Kidneys: High levels of creatinine; if you exercise prior to a lab test, the creatinine will be elevated. Blood urea nitrogen elevated. Forms when proteins break down. Elevates when people are a) dehydrated or b) exercised the day prior to the test. My liver values are of concern. ALT when elevated mildly not of concern; mine have raised each of the last 3 tests. Foods that are good for the liver. “What supplements should I take for peak performance?” Milk thistle Holy basil Dandelion root Non-alcoholic fatty liver disease. I may fall into this category. Metabolism Reset Diet by Dr. Allen Christianson (link needed) Something I do to sleep on int'l flights: an edible of marijuana. Metabolized by the liver; could have contributed to my high levels. Electrolytes Looking at Co2 and chloride levels. My Co2 has dropped. Bone health: More Vitamin D is not better; Above 80 you have increased risk of mortality. If calcium is abnormal, can be caused by abnormal albumin. The blood: You have two components of your blood: cellular (red, white, platelets) and liquid (plasma). My mean platelet volume is okay. My white blood cell count looks great. Either too little or too much can lead to mortality. Red blood cells: Look great. I spend time in the sauna which is great for blood production. My iron levels are fine. An extra steak or two per week wouldn't kill me. Floradix (link) Vitamins and minerals: Folic acid is essential for DNA synthesis. When folate is high, it could mean using a lousy multivitamin. Vitamin B12 is required for proper nerve function; mine is through the roof. Vitamin A is in perfect amount. Red blood cell magnesium the most precise way to measure magnesium in cells. Copper needed in trace amounts. Zinc important for nails, DNA synthesis, chronic disease management; too much causes bad breath, excessive sweating. Black ant extract is great for zinc. Resources from this episode: [pdf-embedder url="https://bengreenfieldfitness.com/wp-content/uploads/2018/09/Lab-Results-WellnessFX.pdf" title="Ben Greenfield Lab Results – WellnessFX"] - - - - - - - -Almsbio Glutathione with Q10 - - - - - - - - - - - - - Episode sponsors: - are the foundation of total human optimization. I highly recommend their toothpaste! Use my link and get 10% off your order. - Give the middle finger to aging. Use Kion Serum anywhere you’d like more vibrant, youthful skin and hair.   - It’s like having a personal trainer in your pocket. Inspiring music, inspiring trainers guiding your through your workout. Use my link and get 30% off a new membership. - Reclaim your inner-warrior. Have more energy. Boost your libido. Jet Pack is like a cup of coffee for your crotch. Enter code “ben” and get yourself 15% off your order at checkout. Do you have questions, thoughts or feedback for me about these lab results? Leave your comments below and I'll reply ASAP!

Some of us eat low-fat diets. Others eat high-protein/low-carb. But very few of us eat high-fat diets. All of the healthy people groups that Dr. Weston A. Price studied ate diets higher in fat than those we eat today. This is one reason that in today's conversation, Sally Fallon Morell, the head of the Weston A. Price Foundation, suggests that we all could benefit from upping our fat intake. More fat in our diet? Why? And how much should we be eating? What is a healthy fat, anyway? And are animal fats even necessary? Sally meticulously answers all of these questions and more, as she dives into Principle #7 of the Wise Traditions diet. She explains in detail the role of fats in biochemical body processes and the role fat played in traditional diets. She makes a compelling case for animal fats, in particular, since the body requires arachidonic acid to function properly and this omega-6 fatty acid is found only in animal fats. After listening to this episode, you will be prepared to challenge the diet dictocrats, and you will probably also be craving a hearty serving of butter, which you may enjoy guilt-free. Learn more about the Wise Traditions dietary principles at westonaprice.org.

In today’s episode of The Plant Trainers Podcast, we talk to Adam Sud about treating drug addiction through a plant-based diet. Adam, a 7th generation Texan, formally weighed over 300lbs, was a drug and food addict suffering from severe depression. Through his own journey he discovered how plants can help others like him overcome addiction. Today he is over 4 years sober and weighs 165lbs. He is a certified holistic lifestyle coach and developed a program using plant-based nutrition as a tool for addiction recovery and relapse prevention. We take the idea of drug, alcohol and food addiction as well as depression to a deeper level with Adam. We’ve seen this pattern come up with many amazing transformational stories. All of us need to really understand why this is such a common theme and what role diet really has in the treatment and healing process.   In this episode we discuss: Family Adam’s low point and how he got there ADD, ADHD and Adderall Addiction and Depression Which came first… Rip and Engine 2 My fault Make the change Sober Living Being comfortable being uncomfortable Arachidonic acid Addressing addiction Passion vs addiction Changing nutrition in rehab   Links to things we mentioned: Adam Sud’s , , by Michael Greger M.D. , Doug Lise by David Clark         Don’t forget to contact us at  with your question for our “Hey Plant Trainers” segment!     Do you want to create lifelong healthy eating habits for you or your family? Are you looking to help prevent heart disease, cancer and chronic diseases? Are you looking for guidance with your plant-based nutrition? We can help. If you are serious about getting results, you may be eligible for a FREE 30-minute Skype or phone consultation, where we can help you with your goals NOW. Easily book your session .    Subscribe to Adam’s Journey by clicking .   We hope you enjoyed this podcast! Please take a moment and  – we would be grateful! This will help get our podcast out to others who may enjoy it. We promise to read your reviews and consider your feedback. This show is for you. Please subscribe to The Plant Trainers Podcast on ,  or  so you will know when we release a new episode. Now also available to ! Help us by spreading the news about our totally awesome Podcast!   Click for a list of our services

How do we age, we burn up, dry up, turn to stone and we rust. This video gives you the details of aging and how you can delay the process.   When Robert Seik, PharmD, owner of Partell Specialty Pharmacy received his training from the American Academy of Anti-Aging Medicine, a physician, Dr. Eric Braverman, lectured to the audience on the processes that cause aging. Simply put, he said we burn up, dry up, turn to stone and we rust.   If you support the body's physiologic symptoms to help us maintain our good health, to maintain good repair and to rid the body of environmental toxins, it is possible to maintain our body's functions as long as we live.   We dry up-our body needs water and it needs certain ions, like Sodium, Magnesium, Potassium and Calcium. These ions tell the water where it belongs. Water needs to flow in and out of cells so it can be used during metabolic processes, lubricate the joints, and help keep the cells clean. If we don't have the right balance of these electrolytes then water doesn't go where it is supposed to go. That's why in Functional Medicine, they focus on Magnesium supplementation, which is found in dark green, leafy vegetables. Sodium is also a large focus, which you can find in pure nutrient dense sea salt, like Hawaiian or Mediterranean sea salts.   Dehydration is also a problem. Mild dehydration may manifest as slight fatigue, brain fog and hunger, Robert recommends that people in Las Vegas drink at least a gallon of water a day as well as 1 Liter per every hour of exercise. This water should be pure water, not exposed to a lot of environmental toxins.   How do we burn up? Inflammation in your body drives the disease process. Even low amounts of inflammation that might be causing a mild amount of pain. This mild inflammation could be causing your cardiovascular system to deteriorate. Over time, mild inflammation can really have a lot of negative health effects. Mild inflammation can transition into overt inflammation, which can cause autoimmune disease. There are inflammatory cytokines on blood tests that can be measured to evaluate just how bad the inflammation is in the body.   Ways to reduce the inflammation would be to avoid or reduce exposure to the things that cause this inflammation. For example, feedlot beef is very different from grass fed beef and you would want to avoid eating the feedlot beef. There are no Omega 3 fatty acids in the feedlot beef and it contains Arachidonic acid, which actually propels the inflammatory molecules. Grass fed beef is rich in Omega 3 fatty acids.   Omega 3 fatty acids are actually one of the top nutrient deficiencies in America. A recommended supplement is to take a high quality supplement of Omega 3 fish oil, 3000-6000 mg/day, even 9000 mg a day for those with people with cardiovascular disease in order to quell that inflammation.   There are other anti-inflammatories as well, such as the herbs Boswellia and Cat's claw. Vit D also reduces inflammation and maybe that is why low vitamin D is associated with diseases of inflammation.   Why do we turn to stone? Environmental chemicals and our body's inability to put Calcium where it really belongs both cause atherosclerosis or hardening of the arteries. We are unable to put the Calcium into the bone because of several factors. Hormones and cofactors are important players in activating and allowing osteoblasts to bring that Calcium into the bone. When these are off balance or depleted the Calcium ends up where it shouldn't-in our arteries.   How do we rust? Our body oxidizes and this is why antioxidants are so important.   Our body oxidizes and this is why antioxidants are so important. We need to start off with a very nutrient dense diet first. We then can add antioxidants such as Vit A, Vit E, Vit C, and Alpha Lipoic Acid (ALA). Robert likes to add CoQ10 to these for complete coverage. Metametrix Ion panel can help you identify your deficiencies, your toxic burden and allows you to measure your total body status of antioxidant nutrients (www.metametrix.com). A Physician must order this test.   So, if we're not drying up, burning up, turning to stone and rusting then our body will maintain better functionality overall including cognition, cardiovascular health, joint and bones and your overall health will improve.   by Robert Seik, PharmD

Arachidonic acid (AA) is released by phospholipase A(2) (PLA(2)) and then converted into vasoactive and inflammatory eicosanoids by cyclooxygenases (COX) and lipoxygenases (LOX). These eicosanoids are important paracrine regulators of vascular permeability, blood flow, local pro- and anticoagulant activity and they play a major role in the local inflammatory response. We have investigated the presence of mRNAs for PLA(2) and for isoforms of COX and LOX in both human endothelial cells (EC) and in human smooth muscle cells (SMC) in culture and in vascular biopsies of human umbilical veins (HUVB) and arteries (HUAB) by using the reversed transcription-polymerase chain reaction (RT-PCR) technique. Results show detectable levels of PLA(2) type IV (cPLA(2)) in cultured EC and SMC and in vascular wall biopsies from HUAB and HUVB. The cultured EC and SMC demonstrate higher levels of both COX-1 and COX-2 with PCR analyses than do vascular wall biopsies from HUAB and HUVB. This indicates a difference in the native expression of COX-1 and COX-2 in cultures of EC and SMC compared to that in biopsies from intact vessel walls. The EC and SMC in culture do not express mRNA for 5-LOX, that was, however, expressed in the vascular wall biopsies. This speaks in favour of a constitutive, i.e, in vivo expression of 5-LOX in SMC in the vascular wall of both umbilical vein and arteries. Thus results from in vitro studies of constitutive COX and LOX expression in EC and vascular SMC in culture cannot simply be extrapolated to represent in vivo conditions.