Podcasts about Cyclo

Kiera is joined by the tooth-healer himself, Jason Dent! Jason has an extensive background in pharmacy, and shares with Kiera where his pharmaceutical experience has bled over into dentistry. This includes the difference between anti-quag and anti-platelet and which medications are probably safe, what to do to shorten the drag time in the pharmacy, how to write prescriptions most efficiently, and more. Episode resources: Subscribe to The Dental A-Team podcast Schedule a Practice Assessment Leave us a review Transcript: The Dental A Team (00:00) Hello, Dental A Team listeners. This is Kiera and today is a really awesome and unique day. It is, think the second time I've had somebody in the podcast studio with me live for a podcast and it's the one and only Jason Dent. Jason, how are you? I'm doing well. Good morning. Thanks for having me. It is crazy. I I watch Instagram real like this all the time where people are like in the podcast and they're hanging out on two chairs and couches and now look at us. We're doing it. Cheers. Cheers.   That was a mic cheer for those of you who are only listening, but yeah, Jace, how does this feel to be on the podcast? It's weird. Like I was not nervous at all talking about it. I got really nervous as soon as you hit play. So if I stumble over my words, please forgive me ahead of time. Well, Jason, I appreciate you being on the podcast because marketing had asked me to do a topic about teledentistry and I was like, oh shoot, that's like not my forte at all. so   You and I were actually chatting in the hot tub. call it Think Tank session and you and I, we have a lot of good ideas that come from that Think Tank. A lot of business. no phones. That's why. We do leave our phones out. But I was talking to Jason and this is actually a podcast we had talked about quite a while ago. Jason has a lot of information on pharmacy. And if you don't know, Jason isn't really, we were going through all of it last night. It's kind of a mock in the tub. And I think it's going to be great because I feel like this is an area, I'm working at Midwestern and   knowing about how dentists, pharmacology was surely not your favorite one. Jason actually helps a lot of dentists with their clearances. And so we were talking about it and I like it will just be a really awesome podcast for you guys to brush up on pharmacology, different things from a pharmacist's side. So Jason, welcome. Thank you. Yeah, no, we were talking about it and here's like, what should I talk about on the podcast next? I have all these different topics and she's like, what do you know? And the only real interaction I have with dentists is doing clearances for procedures. We get them all the time, which makes sense.   Lots of people are on blood thinner, I've always told Kiera, like, hey, I could talk about that. Like, that's kind of a passion of mine. I'm not a dentist. Or my name is Jason Dent. So in Hebrew, Jason means tooth. No, no, no, sorry. Nerves are getting to me. Jason means healer and Dent means tooth. So my name means tooth healer. So, here's a little set. Hold on, on, hold Can we just talk about? I brought that up before you could talk about it more. So.   My name means tooth healer but I did not become a dentist. I know you wanted me to become a dentist. did. I don't know why. I enjoy medicine. I know what you're going to get to already. The things you're going to ask me. There's been years of this. But nevertheless, that's my name. We'll get that out of the way. But you did give me a great last name. So I mean, it's OK. You're All is fair and love here. SEO's up for that. But yeah, Jason, I'm going to get you right into the show. And I'm going to be the host. And we're going to welcome to the podcast show. Jace, how are you?   Good, good, good. Good, good, good. So by getting into clearances, right? This is what you're kinda talking about with you know, before we get to clearances, I actually wanted Jason, for the listeners who don't know you, who haven't talked to you, who don't know, let's kinda just give them like, how did you go from, Kiera wanted you to be a dentist, to now Jason, you are on the podcast talking as our expert on pharmacy. fantastic. I've always really loved medicine, a ton. As a kid getting headaches and taking Excedrin, like you just feel like a miserable pile of crap.   and then you take two pills and all of a sudden you feel better. Like that's amazing, like how does that happen? Also getting ear aches as a kid, just being in so much pain and then taking some medicine and you start feeling a lot better. I always had a lot of appreciation for that. I've always been mechanically inclined. I went to, started doing my undergrad and took biology and learned about ATP synthase, which is a spinning enzyme that's inside the mitochondria, like a turbine engine. I used to work on small engines on my dirt bike and thought that is so cool. So I really got wrapped up into chemistry.   All the mechanics of chemistry really pulled me in. I'm not getting goosebumps. checking. I usually get goosebumps when I think about chemistry. But it's so cool. You think an engine's awesome, like pistons and camshafts and pressures, the cell is the same thing. It's not as loud, so it's not as cool. But it's fascinating. that's why we're like. ⁓   chemistry and really got into coagulation. So I did my residency after pharmacy school. we went to Arizona for three years. ⁓ You did and your main focus, you were never wanting to be the guy behind the counter. No, I haven't done that. Yeah. No, I love them though. I've always really want to go clinical. ⁓ But I love my retail ⁓ pharmacists. They're amazing resources. And ⁓ I use the retail pharmacist every day still to this day, but I went more the clinical route, really love the chemistry aspect of it.   did my doctorate degree and then I did my residency in Reno. Reno's kind That's how we got here everybody. Welcome to Reno. Strategically placed because I was really interested in critical medicine and where we're located we cover a huge area. So we pull in to almost clear, we go clear to Utah, clear to California, all of Northern Nevada. We get cases from all over. So we actually are kind like the first hub of care for lot of areas. So we really get an eclectic mixture of patients that come in that need-   all kinds of different cases that are coming to them. So it's what I really wanted. So I did my residency in critical care there. And then for the next 10 years, I worked in vascular medicine with my final five years being the supervisor of the clinic. Ran all the ins and outs of that. So my providers, two doctors were on our view. So when we talk about dentistry, talk about production, those kinds of things, totally get it. My doctors were the exact same way, my vascular providers. ⁓   There's some pains there, right? You wanna be seeing patients as much as possible, being able to help as many people, keeping the billing up. And had other nurse practitioners, four practitioners, a fleet of MAs, eight pharmacists. We also had that one location we had, going off the top of my head, I think we had eight locations running as well. And we took care of all the different kinds of vascular cases that came to us. Most common was blood clots, ⁓ which is just a...   which is an easier way of saying VTE. There's so many different ways to say a blood clot. Like you might hear patients say, I've had a PE or a DVT or a venous thromboembolism or a clot in my leg, right? They're all clots, but in different locations. Same with an MI, and MI can be a clot as well. ⁓ there's a lot of, everybody's kind of saying the same thing, but sometimes the nomenclature can make it sound hard, but it really is actually pretty simple.   No. And Jason, I love that you went through, you've been in like, and even in your, ⁓ when you were getting your doctorate, you were in the ER. You also worked in retail pharmacy. remember you having a little sticker on your hand. And retail pharmacy, I have a lot of respect for those guys. They have a lot of pressure on them. and then you also, ⁓ what was that test that you had to take that? I don't know. You were like studying forever for it. ⁓ board certification for, ⁓ NABP. Yeah. So I did that board certification as well.   And now you've moved out of the hospital side onto another section in your career. Now in the insurance, right? So it's really, really interesting. So now I'm on the other side reading notes and evaluating clinical appropriateness and trying to help patients with getting coverage and making those kinds of determinations. So yeah, I've really jumped all over. Really love my clinical days. I know. don't I don't I do miss them. But yeah, kind of had a good exposure to a lot of.   pharmacy a lot a lot of dentists actually with all the places that come through which Jason I really appreciate that and honestly I know you are my spouse and so it's fun to have you on but when I go into conversations like this I don't know any of this information and so finding experts and Jason I think here's me talk more about dentistry and my business than I do hear about him on pharmacy so as we were chatting about this I really realized you are a wealth of knowledge because you've been on the clinical side so you've done a lot of patient care and you've seen how   medications interact and I know you've had a few scares in your career and ⁓ you've known some physicians that have had a few scares and ⁓ you've seen plenty of patients pass away working in the ER and gosh in Arizona drownings were such a big deal. I remember when you were in the ER on your rotations I'd be like who died today? Like tell me the stories and you've really seen and now going on to the insurance side I felt like you could just be such a good wealth of knowledge because I know dentists are sometimes so   I would say like maybe just a little more anxious when it comes to medications. I know that dental students from Midwestern were like here was like four months and we had to like pass it, learn it. And Jason, you've done four years plus clinical residency, plus you've been in it. And something I really love about Nevada Medicine is they've been so collaborative with you.   like your heart, your cardiologist, they diagnose and then they send to you to treat with medicine and... Yeah, I've been really lucky being here in Reno too. The cardiology team has been amazing to work with. We started a CHF program, sorry, congestive heart failure program for patients. So we would collaborate with cardiologists. They'd see the cardiologists and then they send them to the pharmacist to really manage all the medications. So there's pillars of therapy ⁓ called guideline directed medical therapy and the pharmacist would take care of all that. So that's gonna be your...   your beta blockers, your ACEs, your ARBs, your Entresto, which would be a little bit better, spironolactone. So just making sure that all these things are dosed appropriately, really monitoring the heart, and make sure that patients are getting better. we've had real positive outcomes when the, sorry, this is totally off topic. do, talk about that study. When we looked at when patients were coming to see our pharmacists in our clinic that we started up, the patients were half as likely to be readmitted. And this was in 2018, and our pharmacists,   We're thinking about all the medications. We're usually adjusting diabetes medications too at the same time. Just kind of naturally just taking care of all the medications because we kind of got a go ahead from the providers, a collaborative practice agreement that we could make adjustments to certain medications within certain parameters. So we weren't going rogue or maverick, but we were definitely trying to optimize our medications as much as possible. And then years later, some studies came out with, I'm sure you've seen Jardins and Farseegh. not trying to, I'm not.   I don't get any kickback from them. I have no conflicts to share. But because our pharmacists were really optimizing that medication, those medications were later shown to reduce hospitalizations and heart failure, even though they're diabetes medications. Fascinating. So it wasn't really the pharmacists. It was just the pharmacists doing as much as they can with all the tools that were in front of them. And then we found out that the patients were going back to the hospital.   half as much as regular patients. So, yeah, being here, it's been so amazing to work with providers here. the providers here want help, want to help patients, don't have an ego. I mean, I just, it's awesome. I love it. I do love how much I think Jason sees me geek out about dentistry and I watching Jay's geek about his pharmacy and how much he loves helping patients. And ⁓ really that was the whole idea of, all right.   Dentistry has pharmacy as a part of it. And I know a lot of dentists are sending in clearances and I know working in a chair side, it would be like, oh no, if they're on warfarin or on their own blood clot, you guys, honestly don't even know half of what I'm talking about because this is not my jam, which is why Jason's here. But I do know that there was always like, well, we got to talk with their provider. And so having Jason come in and just kind of explain being the pharmacist that is approving or denying or saying yes or no to take them off the blood thinners in different parts, because you have seen several dental   I don't know what they're called. What is it? Clarence's? that what comes to you? don't even know. All day my mind, it's like, here is the piece of paper that gets mailed to you to the pharmacist and then you mail it back. So whatever that is. But Chase, let's talk about it because I think you can give the dentist a lot of confidence coming from a pharmacist. What you guys see on that side. When do you actually need to approve or disapprove? Let's kind of dig into that. Yeah. Well, first of all, I think I'm not a replacement for any kind of clinical judgment whatsoever. Every patient's different. But the American Diabetes Association, you   I work with diabetes a lot. American Dental Association has some really great guidelines on blood thinners and I would always reference them. I actually looked at their website today. Make sure I'm up to speed before I get back on this again. They have resources all around making decisions for blood thinners. And I think the one real important thing in putting myself in the shoes of a dentist or any kind of staff that's around a patient that's in a chair, if they say I'm on a blood thinner, right, a flag goes up. At least in my mind, that's what goes up.   Like, okay, how do we get across this bridge? And I think the important thing to really distinct right then when they say they're on a blood thinner is that is kind of a slang word for a lot of different medications, right? Like it's the overarching word that everybody pulls up saying, I'm on a blood thinner. It's like, okay, but I don't know what say. It's like, I have a car. You're like, okay, do you have a Mazda? Do you have?   Toyota, Honda, what do you have? or even worse it'd be like saying I have a vehicle, right? So when somebody says they're on a blood thinner, it opens up a whole box of possibilities of what they're Blood thinners are also, doesn't, when they're taking these types of medications that are quote unquote a blood thinner, it doesn't actually thin the blood, like adding water to the blood, if that makes sense, or like thinning paint, or like thinning out a gravy, right? It doesn't do the same thing. Blood thinners, really what they're doing is they're working on the blood, which.   which is really cool, try not to tangent on that. ⁓ When they're working on the blood, it's not thinning it per se, but it's making it so that the proteins or platelets that are in it can't stick together and make a cloth quite as easy. So whenever somebody's on a blood thinner, I usually ask, what's the name of the blood thinner that you're on? It's not bad that they use that slang, that's okay, on the same page, but it's really broken into two different classes. There's anticoagulant and antiplatelet.   And a way to kind of remember which is which, when residents would come through our clinics, the way that I teach them is a clot is like a brick wall. You know, it's not always a brick wall. Usually the blood is a liquid going through. But once they receive some kind of chemical message, it starts making a brick wall with the mortar, which is the concrete between the and the bricks, the two parts. When it's an anti-quagent, it's working on that mortar part. When it's an anti-platelet, it's working on the bricks part, right? You need both to make a strong clot or strong brick wall.   But if you can make one of them not work, obviously like if your mortar is just water, it's not working, right? You're not gonna make a strong brick wall. So that's kind of the two deviants right there. So that's what I do in my mind real quickly to find out because antiplatelets are usually, so that's gonna be like your Plavix, Ticagrelor, Brilinta. And hold on, antiplatelets are bricks? Good job, bricks. They're the bricks. And so the reason I was thinking you could remember this because I'm, antiplatelets, it's a plate and a plate is more like a brick.   And anti coagulant, I don't know why quag feels like mortar to me, like quag, like, know, it's like slushy in the blood, like it's coagulating. It's a little bit of that, like, honestly, I'm just thinking like coagulated blood is a little bit more mortar-ish. And so platelet is your plate, like a brick, and anti-quag is like.   the gilly between the bricks. Okay, okay, I got it. Yeah, so there's an exception to every rule, but when they're on that Don't worry, this is Kiera, just like very basic. You guys are way smarter listening to this, and that's why Jason's here. No, no, you helped me pass pharmacy school. When we were doing all the top 200, you helped me memorize all know what flexorill is, all right? That's a muscle relaxant. Cyclo? I don't know that part. It's a cyclo, because you guys are cycling and flexing. I don't actually know. just know it's a muscle relaxant, so that's about as far as I got. When we're looking at antitick platelets, so that's the brick part, so that's going to be your, you know,   Hecagrelor, Breitlingta, Clopidogrel is the most common one. It's the cheapest one, so probably see that one the most. Those, I mean, there's an exception to every rule, but that's generally being used after like a stent's placed in the heart. It can be used for VTE, there's some out there, but that's pretty rare. But also for some valves that are placed in the hearts, it can be used for that as well. So antiplatelet, really thinking more like a cardiac event, right? Like I said, there's always an exception to every rule, but that's kind of where my mind goes real quickly, because we're gathering information from the patient.   They're on anticoagulant. Those are like going to be the new ones that you see commercials for all the time. So Xeralto, Alequis, those are the two big ones right now. They're replacing the older one. And also we were supposed to do a disclaimer of this is current as of today because the ADA guidelines do change. this will be current as of today. And Jason, as a pharmacist, is always looking up on that. I had no clue that you are that up to speed on dental knowledge. so just throwing it out there that if you happen to catch his podcast,   a few years back that obviously check those guidelines for sure. But the new ones are the Xarelto and Eloquist. They're replacing the older ones of warfarin. Warfarin's been around for a really long time. We've seen that one. Those are anti-coagulants. So when you're looking, when a patient says that, generally they're on that medication because they've possibly had a clot in the past or they have a heart condition called atrial fibrillation. Those are kind of the two big ones. Like I said, there's always caveats to it, but that's kind of where my mind goes real quickly. And then,   as far as getting patients cleared, the American Dental Association has really good resources on their website. You can look at those and they're always refreshing that up. They even say in their own words that there's limited data around studying patients in the dental chair and with anticoagulants or anti-platelets. It's pretty limited. There's a few studies, some from 2015, some from 2018. There's one as recent as 2021, which is nice. But really, all of those studies come together and it's really more of an expert consensus.   And with that expert consensus, they have kind of simplified things for dentistry, which is really nice. ⁓ comparing that to, we have more data for like total hip replacement, total knee replacement. We have a lot of data and we know really what we should be doing around then. But going back to dentistry, we don't have as much information, so they always say use clinical judgment, but they do give some really great expert guidance on that. So if a patient's on an anticoagulant, ⁓   they generally recommend that it doesn't need to be stopped unless there's a high bleeding risk for a patient. as a provider or as a clinician in the practice, you can be looking at high bleeding risk. Some things that make an oral procedure a little bit lower risk is one, it's in the compressible site, right? Like we can actually put pressure on that site. That's the number one way to stop bleeding is adding pressure. It's not like it's in the abdominal cavity where we can't get in and can't apply pressure. So number one, that kind of reduces the bleeding risk.   is number one. Two, we can add topical hemostatic agents. Dentists would know that better than me. There's a lot of topical ways to do that. So not only pressure, but there's those things as well. And also, but there are some procedures that are a little bit more likely to bleed. And that's where you and dentists would come in hand in What's the word in APO? Oh, the APOectomy. I got it right. Good job. like, didn't you tell me last night that the ADA guideline was like what?   three or four or more teeth? great question. So you can extract one to three teeth is what their expert consensus One to three teeth without. Without really managing or stopping anticoagulation or doing anything like that. I think that's some good guidance from them. I'm gonna add a Jasonism on that though. So with warfarin, I do see why dentists would be a little bit more conservative or worried about stopping the warfarin because warfarin isn't as stable as these newer agents. Warfarin, the levels.   quote unquote levels can go really high, they can go really low. And if the warfarin levels are high, they're more likely to bleed. So I do think it makes sense to have a really recent INR. That's how we measure what the warfarin's doing. I think that makes a lot of sense, but the ADA guidelines really go into the simplification version of all these blood thinners. Generally, it's recommended to not stop them because the risk of stopping them outweighs the benefit of stopping them in almost every case. Almost every case.   ⁓ So when you're with that patient, right, they say I'm on a blood thinner, finding out which kind of blood thinner that they're on, you find out that they're on Xeralto, right? How long have you been on Xeralto for? I've been on it for years. You don't know exactly why, but if they haven't had any recent bleeding, you're only gonna remove one tooth. ⁓ You can do what's called a HasBlood score. That kind of looks at the bleeding risk that they'd have. That'd be kind of going a notch above, but in my mind, removing one tooth isn't a real serious bleeding risk. I'd love to hear from my dentist friends if they...   disagree, right, but ADA says one to three tooth removals, extractions, that's the fancy word. Extractions, yeah, for extracting teeth out. Is not really that invasive. Sure. It's not that high risk, so it's usually perfectly fine. So if a patient was on Xarelto, ⁓ no other, this is in a vacuum, right? I'm not looking at any other factors, which you should be looking at other factors. I would be perfectly fine to just remove one to two.   And when those clearances come in, because dentists do send them, talk about what happens. You guys were working in the hospital and you guys would get these clearances all the time. do. We get them so often. I mean, we get like four or five a day. We'd love to give it to our students, student pharmacists, and ask them what to do. And they would usually look up the American Dental Association guidelines and come up with something. We're like, yep, that's what we say too. In fact, we say it so many times a day that we have a smart phrase.   which just blows in the information real quickly and faxes it right back to the So it's like a copy paste real quick. So what I wanted to point out when Jason told me this is dentists like hearing this and learning this, this can actually save you guys a ton of time to be able to be more confident, to not need to send those clearances on. And we were actually talking last night about how I think this might be a CYA for dentists. like, as we were talking, I think Jason, you seeing so many other aspects of medicine, like you've literally seen patients die, you've seen other areas.   And so coming from that clinical vantage point, we were realizing that dentists, we are so blessed to live in an injury. I enjoy dentistry because possibly there's someone dying, not super high, luckily in dentistry. The only time that I have actually had a doctor have a patient pass away, and it was only when they were completely sedated and doing ⁓ some other things, but that was under the care of an anesthesiologist. And so that's really our high, high risk. And so hearing this, Jason,   That was one of the reasons I wanted him to come on is to give you doctors more confidence of do we have to always send to a pharmacist? I mean, hearing that on the pharmacy side, they're just sending these back and not to say to not see why a to not cover this because you might be questioning like, well, do I really need to? But you also were talking about some other ways of so number one, you guys are just going to copy back the 88 guidelines. So so 88 guidelines. Yeah. And I think that that gives a lot of confidence to a provider or a dentist is that you can go to the 88 guidelines and read them, right? Like you're listening to some   nasally monotone pharmacist on a podcast. Rumor has it, people love him at the hospital. were like, you're the voice, he's been told he has a good radio So for the clinic, I was the voice. Like, yeah, you've reached the vascular clinic, right? And they're like, oh my gosh, you're the voice. But sorry, you me distracted. That'll be your next career, Jace. You're going to be a radio host. OK. I would love that. I love music. But you're hearing from a nasally guy, but you can actually read the ADA guidelines. You just go right to the ADA, click on Resources, and under Resources, it has the   around anticoagulants, I think that's the best way to get a lot of confidence about it because they have dentists who are the experts making calls on these. I'm just reiterating what they say, but I think it makes a lot of sense to help providers. And the reason why my heart goes out to you as well is having the providers that used to work underneath me, they're always looking for our views, which is a fancy way of making sure that they're drilling and filling. Can I say that? Yeah, can say drilling and filling. They're being productive, right? They're being productive, right?   They're always looking to make sure if a patient's canceling, like get somebody in here. Like I need to be helping people all day long. That's how I, we keep the lights on. That's how I help as many people. And so if you have a patient coming in the chair and it has an issue, they say I'm on Xeralto. Well, you can ask real quickly, why are you on Xeralto? I had a clot 10 years ago. my gosh. Well, yeah, we're pretty good to go. Then I'm not worried. We're only removing one tooth or we're just doing a cavity or a cleaning. Something like that. Shouldn't be an issue whatsoever because there's experts in the dental. ⁓   in the dental society, the ADA guidelines that recommend three teeth or less, minimally invasive. They really recommend if it's gonna be really high bleeding risk. And clinically, that's where you would come in, ⁓ or yourself. know, apioectomy is one that's like on the fence line. I don't know where implants set. though, and like we were talking, implants aren't usually like a date of procedure. Most people aren't popping in, having tooth pain, and we're like, let's do an implant. Now sometimes that can be the case, but typically that one's gonna have   a few other pieces involved. And so that is where you can get a clearance if you want to. ⁓ But we were really looking at this of like so many dentists that I know that you've seen will just send in these clearances because they are. And I think maybe a way to help dentists have more confidence is because you know, I love routines. I love to not have to remember things. So why don't we throw it in, have the team member set it up where every quarter we just double check the ADA guidelines. Are there any updates? Are there any other things that we need to do on that? That way you can just see like   getting into the language of this, of what do I need to do? Because honestly, you guys, know pharmacy was not a big portion for it, so, recommending different parts, but I think this is such a space where you can have confidence, and there's a few other things I wanna get to, and I you- I some pearls too. Okay, go. I'm so when she get me into talking about drugs, I'm not gonna stop. So, some other things around that too is these newer blood thinners like Xarelto Eloquist, they now have reversal agents, so a lot of providers in the past were really worried about bleeding because we can't turn it off. We can turn those off. Warfarin has reversal as well, right?   So I'm looking at these patients. It's really low risk. It's in the mouth, generally speaking. Very rarely are they a high bleeding risk. Now if you're doing maxillofacial surgery, this does not apply, right? This does not apply whatsoever. you're like general dentist, you're pediatric dentist. Yeah, yeah, and it's kind of on the fly. So just trying to really help you to be able to take care of those patients on the moment, have that confidence, look at the ADA guidelines, have that in front of you. I don't think it's a bad thing to ever...   check with their provider if you need to. If you're thinking, I feel like I should just check with the provider, I would never take that away from you. But I just want to kind of steer towards those guidelines that I have to help. But what did you want to share? No, yeah, I love that. And I think there were just a few other nuggets that we were chatting about last night that can help dentists just kind of get things passed a little bit easier. So you were mentioning that if they were named to their cardiologist, what was it? was like, who is the last? Great question. Yeah, when a patient's on a blood thinner,   It could be prescribed by the cardiologist. It could be prescribed by the family provider or could have been punted to like a vascular clinic like where I was working. It can go to any of those. And when you send that fax, right, if it goes to the cardiologist and it's supposed to go to the family care provider, like it just kind of goes, goes nowhere, right, from there. So I think it's a really good idea to find out who prescribed it last. If the patient doesn't know who prescribed their blood thinner last, you can call their pharmacy. I call pharmacies all day long.   I have noticed in the last year, they are way easier to get a hold of, which has made my job a lot easier, working on the insurance portion. So reaching out to the pharmacy, finding out who that provider is and sending it to them, because they should be able to help with that. I thought that was a good shift in verbiage that you had of asking instead of like the cardiologist, because that's who you would assume was the one. But you said like so many times you guys would take care of them, and then they go back to family practitioner, and you guys would get the clearances, but you couldn't clear because you weren't overseeing. So just asking the patient.   who prescribed their medication for them last time. That way you can send the clearance to the correct provider. then- And they might not know. You know patients, right? They're like, I don't know, my mom's or else, I don't know who gave it to me. Somebody told me I need to be on this. But at least that could be another quick thing. And then also we were talking last night about-   ⁓ What are some other things that dentists can do when like writing scripts to help them get what I think like overarching theme of everything we discussed is one how to help dentists have less I think drag through pharmacy. ⁓ Because pharmacy can take a little while and so perfect we now know the difference between anti-quag and anti-platelet. We know which medications are probably safe. We know we can check the ADA guidelines so that we were not having to do as many clearances. We also know if they're on a medication to find out and we do need a clearance.   who we can go to for the fastest, easiest result. And now, in talking about prescriptions, you had some really interesting tips that you could share with them. Yeah, so with writing prescriptions, right, pharmacies are pharmacies. So I'm not gonna say good thing or bad thing. There are challenges working with pharmacies. I'm not gonna play that down at all. ⁓ If you're writing prescriptions and having issues and kickbacks from pharmacies, there's some interesting laws around ⁓ writing prescriptions. Say that you're trying to ⁓ prescribe   augmentin, you know, 875 BID, and you tell the patient, hey, I want you to take this twice a day for seven days, and then you put quantity of seven, because you're moving fast, right? You want it for seven days, quantity of seven. Quantity would actually be 14, right? It's not that big of a deal. Anybody with common sense would say if you're taking a pill for twice a day for seven days, you need 14 tablets. But LAHA doesn't allow pharmacists to make that kind of a change, unfortunately. They have to follow what you're saying there. So you're going to get a...   An annoying callback that says, you wrote for seven tablets. I know you need 14. Is that OK? Just delays things, right? So ⁓ I really like the two letters QS. That's Q isn't queen. S isn't Sam. Yeah. It stands for quantity sufficient. So you don't have to calculate the amount of any medication that you're doing. So for me, as a pharmacist, when I was taking care of patients, I hated calculating the amount of insulin they would need for an entire month. So I would say.   Mrs. Jones needs 15, I'd say 15 units ⁓ QD daily. ⁓ And then I say QS, quantity sufficient, ⁓ 90 day supply through refills. So the pharmacy can then go calculate how much insulin that they need. I don't have to even do that. So anytime you're prescribing anything, I like that QS personally. So that lets the pharmacy use ⁓ common sense, as I like to call it, instead of giving you a call. I think that's super helpful. I also thought of one thing too.   going back to blood thinners is when it's kind of like a real quick, like they're not gonna have you stop the blood thinner at all. like you're seeing if you can stop the blood thinner for a patient, there's some instances it's just not gonna happen. And that's whenever they've been, they've had a clot or a stroke or a heart attack within the last three months. Three months. Yeah, that's kind of like the.   Because so many people are like, they had a heart thing like six years ago. And so I think a lot of my dentists that I worked with were like, we got to stop the blood thinners. But it sounds like it's within three months. Yeah, well, I'm just the time. Like this is general broad strokes. What I'm just trying to say is when you want to expect a no real quick. Got it. Right. So because benefits of stopping a blood thinner within those first three months of an event is very, very risky versus the, you know, the benefit of reducing a little bit of blood coming out of the mouth. Right. Like that's not that bad.   when somebody's had a stroke or a heart attack or pulmonary embolism, a clot in the lung, like we can't replace the lung, heart or brain very easily. We can replace blood a lot better. We've got buckets of it at most hospitals have buckets of it, right? So I'm always kind of leaning towards I'd rather replace blood than tissue at all times. So that's kind of a quick no. If they've had one those events in the last three months, we are really, really gonna watch their brain instead of getting.   root canal, right? Like really worried about them. So you'll just say no. And they could the dentist still proceed with the procedure or would you recommend like a three month wait? Or is it provider specific way the pros and cons because sometimes you need to get that tooth out. Great question. think then it's going to come into clinical. That's that's when you send in the clearance, right? Like, and it's great to reach out to the provider who's managing it for you. But I think it's kind of good to know exactly when you get a quick no quick no is going to be less than three months.   ⁓ Or when it's going to be like a kind of a typical, yeah, no problem. If it's been no greater than six months, they're on the typical anticoagulants or alto eloquence. Nothing crazy is going on for them. You're only removing two teeth. This is very, very low risk. But again, I'd urge everybody to read the ADA guidelines. That way you feel more comfortable with it. I'm not as eloquent as they do. They do a real good job. So I don't want to take any of their credit. I think they do a real good job of simplifying that and making you feel confident with providing.   more timely care for patients. Which is amazing. And Jayce, one last thing. I don't remember what it was. You were talking about the DEA and like six month rule. yeah. Let's just quickly talk about that and then we'll wrap this because this is such a fascinating thing for me last night. Yeah. So when comes to prescribing controlled substances, most providers have to have a DEA license. OK. First of all, though, what's your take on dentist prescribing controlled substances? ⁓ I don't think, you know, I worked on the insurance side of things. Right. And I look at the requirements for the   as the authorizations, what a patient, the criteria a patient needs to hit in order to qualify for certain medications. A lot of times for those controlled substances, they have pretty significant issues going on, like fibromyalgia or cancer-related pain or end-of-life care versus we don't, in all my scanning thread, I don't have a ⁓ perfect picture memory. Sure. But I don't usually see oral.   pain in there. There is some post-operative pain that can be covered for those kind of medications but I really recommend to keep those lower and in fact in a lot of our criteria it recommends you know have they tried Tylenol first, they tried, have they filled NSAIDs or are they contraindicated with the patient. So really they should be last line for patients in my two cents but there's always going to be a caveat to the rule right? Of course. comes through that has oral cancer and you're taking   like that would make sense to me. Got it, so then back to the DEA. Yeah, okay. Okay, ready. So as a provider, you should be checking the, if you're doing controlled substances, you should be checking the prescription drug monitoring program, or sometimes called the PDMP, looking to see if patients are getting ⁓ controlled substances from another provider. So it's really just a check and balance to make sure that they're not going from provider to provider to getting too many narcotics and causing self harm or harm to others.   And so with checking that PDMP before prescribing, I think a lot of providers do that. A lot of softwares that I'm aware of, EMRs, electronic medical records, sometimes have links so that you can do that more quickly. However, I don't think it's as intuitive that they need to be checking that every six months in some states. And like here in Nevada, you're supposed to be checking it every six months, not for a patient, but for your actual DEA registration to see if anybody else is prescribing underneath you. Because if you don't check that every six months, you could get in some serious trouble with...   not only DEA, but even more the Board of Pharmacy and your state. Now, I don't know all 50 states, so I check with your state to see if you need to be checking that every six months, but set an alarm just to check that real quickly, keep your nose clean. ⁓ I've had providers, I've had to remind to do that. And if somebody was using your account, prescribing narcotics, you'd never know unless you went and checked that PDMP.   Yeah, I remember last night you were like, and if that was you, I would not want to be you. The Board of Pharmacy is going to be real excited to find you. So that was something where I was like, got it. So, and we all know I'm big on let's make it easy. And Jason, I love that you love this so much and you just brought so much value today. And like also for me, it's just fun to podcast. fun. Yeah. But I got a nerd out on my world a little bit. Bring it into yours. I work with dentists or at least you know, when I was working in Vascular Clinic all day long. Great questions that would come through. Yeah.   So I think for all of us, as a recap on this is number one, I think setting yourself ⁓ some cadences. So maybe every quarter we check our ADA guidelines and we check our, what is it, PDMP. PDMP. so each state, so they call it Prescription Drug Monitoring Program. We need that. Yeah, but there are different acronyms in different states, though. That's just what it's called in Nevada. I forget what it is in California, but you can check your state's prescription monitoring program, make sure that opioids aren't being prescribed under your name. Got it. So we just set that as a cadence.   We know one to three teeth most likely if they're on a blood thinner is According to the 88 as of today is good to go You know things that are going to get a quick know are going to be within the last three months of the stroke the heart attack or the Clot I'm thinking like the pulmonary embolus. Yeah, that's what we're trying to prevent   Those are gonna be quick knows and then if we're prescribing, let's do QS. We've got quantity is sufficient so that we're not getting phone calls back on those medications that we are. And then on narcotics, just being a bit more cautious. Of course, this is provider specific and in no way, or form did Jason come on here to tell you you are the clinical expert.   Jason's the clinical expert on medications. And if you guys ever have questions, I know Jason, you geek out and you want to talk to people so that anyone wants to chat shop. Be sure to reach out and we'll be able to connect you in. we've even talked about possibly, so let me know listeners. You can email in Hello@TheDentalATeam.com of ask a pharmacist anything. I talked to Jason. I was like,   We'll just have them like send in questions and maybe get you back on the podcast or we do a webinar. But any last thoughts, Jace, you've got of pharmacy and dentistry as we as we wrap up today? No, I think that's pretty much it. So check the ADA guidelines. I think it's really good to have cross communication between professions. Right. If you're working with the pharmacy, CVS, Walgreens or something like that or Walmart, I know that it can be challenging. Right. They're under different pressures. You're under different pressure. So I think ⁓ just coming in with an understanding, not being angry at each other.   you know what mean, is super beneficial and working together. When it comes to it, every dentist that I've talked to is actually worried about their patient. Every pharmacist that I've worked with is really worried about the patient as well. So we're trying to accomplish the same thing, but we have different rules and our hands are bound in different ways that annoy each other, right? Like I know Dr. Jones, want 14 tablets, but you said seven. And I know Common Sense says I should give them 14, but I've got to make that change.   knowing that their hands are tied by the law. They can't use as much common sense, which is aggravating. I mean, that's why I love what I gotta do here. I gotta just kind of help a lot more and use common sense and improve patient care. But those kinds of things I think are really beneficial as you work together and then not being so afraid of blood thinners, right? So I think those guidelines do a great job of giving you confidence and not worrying about the side effects. And there's a lot of things that you can do locally for bleeding.   You have a lot of control over that. I think that's pretty cool, the tools they have. Yeah. And at the end of the day, yes, you are the clinician. You are the one who is responsible for this. so obviously, chat, but I think collaborating, talking to other pharmacists, talking to them in your state, finding out what are the state laws, things like that I think can be really beneficial just to give you peace of mind and confidence. And again, dentistry, are maybe a bit more risk adverse because luckily we don't have patients dying That's great thing. Yeah, that's fantastic. I want my dentists to be risk adverse. I think so too. But Jason, I appreciate you being on the podcast today.   And for all of you listening, ⁓ more confidence, more clarity, more streamline to be able to serve and help our patients better. if we can help you in any way or you've got more questions, reach out Hello@TheDentalATeam.com. And as always, thanks for listening. I'll catch you next time on the Dental A Team podcast.  

Cyclo-cross has never not been a part of the Rodeo story, even if it hasn't been front and center. For a company that doesn't not make cyclo-cross-capable bikes, all these double negatives leave us pondering the sport every time we hear #crossiscoming. This year, Stephen answered the call of cyclo-cross, and so too did Cam Little, a Rodeo rider from West Virginia and Marian University. Now that the season has wrapped up, it was time to podcast about it, even if Logan, our host, is somewhat of a cyclo-cross skeptic. Host: Logan Jones-WilkinsGuests: Stephen Fitzgerald and Cameron Little Editor and Producer: Logan Jones-Wilkins Hosted on Acast. See acast.com/privacy for more information.

Nou capítol de Viatge Electrònic ja disponible!! Avui programa en format dj mix per a fer baixar el torrons. Avui escoltareu temes downtempo i deep house. Enllaç de les plataformes al link de la bio. Tracklist: 1- Charlotte Gainsbourg - Deadly Valentine (Soulwax Remix) - Deadly Valentine (Because Music, 2017) 2- Matteo Ceccarini feat. D'amato - Firefliess (Ensaime Remix) - Fireflies (Deriva Collective, 2022) 3- Jo Bubbles - Pantoufles Plage - Molntjänst (Self Released, 2022) 4- Zopelar - We Can Make It - Call It Love (Apron Records, 2025) 5- Ed Wizard & Disco Double Dee - Disco Dimension - Editorial #7 (Editorial, 2013) 6- Parallel Dance Ensemble - Shopping Cart - Possessions And Obssessions (Permanent Vacation, 2011) 7- Jügen Paape - So Weit Wie Noch Nie (Original Mix) - So Weit Wie Noch Nie (Kompakt, 2002) 8- Bedouin - Better Than This - Into the Wind (Human By Default, 2024) 9- D'Al Senio feat. ML Dubois Kone - On the Move - Owl's Touch (Switch Records, 2020) 10- Federico Martelli feat. Hue - Unsogno - Unsogno (Self Released, 2025) 11- Mark Grant - Jazzy Kinda Sum'n (Original Mix) - Jazzy Kinda Sum'n (Cyclo, 2000) 12- Cos-Ber-Zam - Ne Noya (Daphni Mix) - Jiaolong (Jiaolong, 2012)

Vous pouvez joindre Joueurs info service au 09 74 75 13 13, de 8h à 2h, 7 jours sur 7. Votre appel est anonyme et non surtaxé (coût d'une communication locale depuis un poste fixe ou inclus dans les forfaits des box et des mobiles).Que vous soyez concerné directement ou indirectement par un problème de jeu excessif, n'hésitez pas à appeler Joueurs info service, vous y trouverez :Des professionnels formés aux difficultés rencontrées avec la pratique de jeu excessifUne écoute sans jugement et confidentielleDes informations précises, une aide personnaliséeDes orientations adaptées à votre situationHébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

Have you ever met someone whose imagination reminds you that creativity can heal, teach, and connect us all?In this inspiring episode of Real Talk with Grace Redman, I sit down with Drew Robinson, dynamic author, screenwriter, and creative visionary whose stories blend fantasy, science fiction, and heartfelt human connection.Drew's journey is a testament to the power of storytelling not just as art, but as transformation. Living with autism, he has used writing to navigate emotion, build connection, and turn challenge into creativity. His books from Lexa and the Gordian Maze of Terror to Vampire Academia explore courage, identity, and empathy through strong, imaginative characters and powerful themes.Drew is one of the kindest humans I have connected with. His heart and soul touched me in a way that no one else has. What You'll Hear in This Episode:

"Pour la journée internationale du diabète, on entame l'épisode avec quelques recommandations. On parle également, boîte à livre, art de rue et science-fiction. Que la Petite Reine soit avec vous !!"Hébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

Le vélo Vert Festival déménage et change de date. Direction Bourg St MauriceHébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

Chapo De Bruxelles à l'Atlas marocain : cet épisode des Socquettes en Titane mêle grand voyage à vélo, chronique engagée et artisanat cycliste. On parle bikepacking, partage, lenteur, et peinture de cadres avec Carte Blanche Custom(Bruxelles). Une virée sonore qui donne envie de préparer ses sacs, de (re)peindre son cadre… et de repartir. L'épisode en bref Le voyage : Pyrénées → Espagne → Portugal → ferry → Maroc (Marrakech, Ouarzazate, Essaouira, Agadir), puis retour par l'Algarve, Sardaigne, Italie, remontée jusqu'en Belgique. Bikepacking vs cyclotourisme : confort de jour contre confort du bivouac ; sacs compacts vs sacoches + porte-bagages ; possibilités hybrides. Peinture de cadres : démontage, masquage précis (vinyl cutter/“ploteuse”), apprêt, couches, vernis et ponçage entre couches ; un travail d'artisanat qui prend du temps. Chronique : “pédaler pour demain” — le vélo comme utopie concrète, à hauteur de ville et de cœur. Les voix & l'équipe Animation Clément Soupart — producteur-animateur du podcast Les Socquettes en Titane (studio bruxellois, rendez-vous vélo en direct puis en podcast). Chronique Katia – « La nomade sédentaire » — chronique sur l'utopie cyclable, la lenteur choisie et l'espace public apaisé. Invités Antoine (voyageur à vélo) — itinérance jusqu'au Maroc via une trace « Caravans North », gestion des rencontres, de la météo et de la déconnexion numérique. Dorian – Carte Blanche Custom (Bruxelles) — peinture de cadres personnalisée : masquage de précision, finitions haut de gamme, collaborations avec des marques gravel/route (ex. OPEN). Points clés à retenir Voyager seul… pour mieux partager : la solitude révèle l'envie de rencontres ; on finit souvent par rouler à deux ou en petit groupe quelques jours. Mixer les approches : combiner sacs de bikepacking et porte-bagages avec dry-bags sanglés pour garder de la modularité (courses, eau) sans alourdir à l'excès. Peindre un cadre, c'est surtout de la préparation : masquage des filetages/inserts, apprêt d'adhésion, ponçage pour l'accroche, couches de peinture puis vernis dans la bonne fenêtre de temps ; reponçage pour la finition. Utopie concrète : le vélo ne sauve pas tout, mais il sauve des journées — une forme de résistance joyeuse au quotidien urbain. Écouter l'épisode ? ? Partage : #Bikepacking #Vélo #Gravel #Bruxelles #Maroc #Atlas #PeintureVélo #OpenCyclesHébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

Dans ce nouvel épisode d'En Roue Libre, Gordon De Winter, Fred Amorison, Gérard Bulens et Félix Pouilly reviennent sur la victoire de Marion Norbert-Riberolle à Ruddervoorde. Et bien sûr quelques mots sur leurs attentes concernant la saison de cyclo-cross.  

Ozlem Goker-Alpan, MD, Founder and President, Lysosomal & Rare Disorders Research & Treatment Center (LDRTC) and Raphael Schiffmann, MD, of the Texas Christian University, discuss best practices to identify and treat neurologic problems associated with lysosomal disorders.This continuing education activity is provided through collaboration between the Lysosomal and Rare Disorders Research and Treatment Center (LDRTC), CheckRare CE, and AffinityCE. This activity provides continuing education credit for physicians, physician assistants, nurses, nurse practitioners, and genetic counselors. A statement of participation is available to other attendees. To complete the program and obtain credit, visit https://checkrare.com/learning/p-lysosomal-disorders-and-the-brain/ Support for this educational activity provided by Takeda and Ultragenyx.Learning ObjectivesAfter participating in the activity, learners should be better able to:Describe the role of the neurologist in the team approach to careList best practices to assess neurologic and cognitive involvement  in persons with LDsCite best practices to assess developmental delay and regression in pediatric patients with suspected LDsDescribe the latest clinical research to improve central outcomes in persons with LDs and central nervous system involvementFacultyOzlem Goker-Alpan, MD, Founder and President, Lysosomal & Rare Disorders Research & Treatment Center (LDRTC), Fairfax, VA Raphael Schiffmann, MDTexas Christian University,Fort Worth, TXDisclosuresAffinityCE staff, LDRTC staff, planners, and reviewers, have no relevant financial relationships with ineligible companies to disclose. Faculty disclosures, listed below, will also be disclosed at the beginning of the Program.Ozlem Goker-Alpan MDDr. Goker-Alpan is on the Advisory Board/Consultant for Chiesi, Takeda, Sanofi, Prevail/Lilly, Sparks Therapeutics, Uniqure, Exegenesis, Astellas, Freeline, Team Sanfilippo. She receives grants/research support from Chiesi, Sanofi, Takeda, Prevail/Lilly, Spark Therapeutics, Amicus, Freeline, Sangamo, Cyclo, Odorsia, $DMT, Homology, Protaliz. She is on the speaker bureau for Sanofi, Takeda, Amicus, Chiesi.Raphael Schiffman, MDDr. Schiffmann is consultant for Amicus Therapeutics, Protalix Biotherapeutics, Chiesi Farmaceutici and 4D Molecular TherapeuticsMitigation of Relevant Financial RelationshipsAffinityCE adheres to the ACCME's Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CME activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity. Conflicts of interest for presenting faculty with relevant financial interests were resolved through peer review of content by a non-conflicted reviewer. PhysiciansThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.Physician AssistantsThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physician Assistants should claim only the credit commensurate with the extent of their participation in the activity.NursesContinuing Nursing Education is provided for this program through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation (ANCC). This activity provides a maximum of 1 hours of continuing nursing education credit.Nurse PractitionersThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Nurse practitioners should claim only the credit commensurate with the extent of their participation in the activity.Genetic CounselorsCategory 2 CEUThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credit™. Genetic counselors should claim only the credit commensurate with the extent of their participation in the activity.CME InquiriesFor all CME policy-related inquiries, please contact us at mailto:ce@affinityced.comSend customer support requests to mailto:cds_support+ldrtc@affinityced.comCopyright© 2025. This CME-certified activity is held as copyrighted © by Lysosomal and Rare Disorders Research and Treatment Center (LDRTC) and AffinityCE. Through this notice, Lysosomal and Rare Disorders Research and Treatment Center (LDRTC) and AffinityCE grant permission of its use for educational purposes only. These materials may not be used, in whole or in part, for any commercial purposes without prior permission in writing from the copyright owner(s).

durée : 00:03:50 - Le coup de cœur, ici Orléans - Le dimanche 7 septembre 2025, le Cyclo Spectacle débarque à Darvoy pour une expérience inédite ! Enfourchez votre vélo et laissez-vous guider à travers un parcours surprenant mêlant arts de la scène et découvertes locales. Départ dès 14h00 à Darvoy. Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.

Nous sommes en août, période de vacances estivales et de chassé-croisé, je vous propose de redécouvrir le témoignage de Gaëtan. Gaëtan nous emmène faire le tour du Sud-Ouest à vélo et parcourir le chemin de Saint-Jacques-de-Compostelle. Un voyage synonyme de l'été !Dans cet épisode, on se demande comment :➕Etre dépaysé en partant à la découverte de sa région (attention traversée des Pyrénées en vue !)

Radio Sports, partenaire média du championnat BikingMan, revient sur l'étape Alpes-Maritimes 2025 qui a tenu toutes ses promesses.1000 km, 52 cols mythiques et plus de 22 000 m de dénivelé positif ont façonné cette aventure extrême, où chaque coureur a dû puiser profondément dans ses ressources physiques et mentales. ? Un podium forgé dans la souffrance et l'émotion Résultats Top 5? Rémi Borrion (Dijon) — 53h02Déjà triple vainqueur BikingMan, Rémi signe sa 4e victoire sur l'épreuve, qu'il qualifie lui-même de « plus belle ». Malgré des nausées dès les premiers kilomètres et un départ prudent (4e au CP1), il a su renverser la course grâce à son expérience et à une stratégie millimétrée.? Bastien Froidevaux (Suisse) — 54h40Pour son premier BikingMan, cet ancien pro venu de Lausanne visait avant tout l'aventure. Il a trouvé bien plus : des émotions brutes, jusqu'aux larmes dans la descente du Turini, et une deuxième place méritée après avoir dominé les premiers checkpoints.? Jan Gutermann (Île-de-France) — 60h10Handicapé par un genou douloureux et des soucis de selle, il n'a jamais lâché, incarnant parfaitement l'esprit ultra-cycliste.4e : Yannick Rougier (Montpellier) — 63h15Impressionnant de régularité et de gestion d'effort sur les plus longues rampes.5e : Steven Leroy (Le Havre) — 65h06Toujours combatif, il complète ce Top 5 d'un niveau exceptionnel. ? Chaleur accablante, cols sans fin : une édition redoutable Le décor était planté : une canicule dès la première journée a provoqué de nombreux abandons. Bastien Froidevaux confiait :« L'avant-dernier col, il n'y avait pas un arbre pendant une heure. Avec la chaleur, c'était terrible. »Mais c'est aussi pour cela que le BikingMan fascine : repousser ses limites, trouver des solutions dans la difficulté, gérer le corps et la tête sur trois jours sans filet. ?‍♂️ Entre performance et introspection Bastien résume l'état d'esprit partagé par beaucoup :« On fait du sport pour vivre ces émotions. On évacue tout. Comme dans la vie : tu as froid, tu trouves une solution, tu dors où tu peux. »Quant à Rémi, ses 15 000 km déjà accumulés cette année parlent pour lui. Il enchaînera dès le mois prochain avec le BikingMan Aura, toujours en quête du titre sur le championnat. ? Des partenaires fidèles pour équiper les ultra-cyclistes Ekoï, équipementier officiel, présentait une collection conçue avec Axel Carion (fondateur du BikingMan) pour répondre aux exigences extrêmes : maillots à flasques intégrées, vestes techniques, chaussettes et gants pensés pour l'ultra-distance.Go'lum, la frontale ultra-légère « qu'on oublie sur le casque », testée dès les premières éditions et encore perfectionnée cette année avec des modes auto-adaptatifs pour prolonger l'autonomie. ? Suivez la suite du championnat avec Radio Sports Radio Sports continue de couvrir tout le championnat BikingMan 2025. Retrouvez bientôt :le résumé du BikingMan Aura en juillet,puis d'autres étapes spectaculaires à travers le monde.? Pour ne rien manquer, abonnez-vous à nos alertes et suivez-nous sur les réseaux sociaux !Hébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

Ozlem Goker-Alpan, MD, Founder and President, Lysosomal & Rare Disorders Research & Treatment Center (LDRTC) and Ravi Kamath, MD, PhD, of Fairfax Radiological Consultants & Inova Health System and University of Virginia School of Medicine Fairfax, Virginia, USA discuss best practices to identify and treat bone problems associated with lysosomal disorders.This continuing education activity is provided through collaboration between the Lysosomal and Rare Disorders Research and Treatment Center (LDRTC), CheckRare CE, and AffinityCE. This activity provides continuing education credit for physicians, physician assistants, nurses, nurse practitioners, and genetic counselors. A statement of participation is available to other attendees.This educational program is supported by an educational grant from Takeda and Ultragenyx.To obtain credit, visit https://checkrare.com/learning/p-skeletal-involvement-in-lysosomal-disorders/quizzes/evaluation-skeletal-involvement-in-lysosomal-disorders/ FacultyOzlem Goker-Alpan, MD, Founder and President, Lysosomal & Rare Disorders Research & Treatment Center (LDRTC), Fairfax, VA Ravi Kamath, MD, PhD,Fairfax Radiological Consultants & Inova Health System and the University of Virginia School of Medicine, Fairfax, VirginiaDisclosuresAffinityCE staff, LDRTC staff, CheckRare staff, planners, and reviewers, have no relevant financial interests to disclose. All faculty disclosures are listed below and are included in the beginning of each presentation.Dr. Goker-Alpan is on the Advisory Board/Consultant for Chiesi, Takeda, Sanofi, Prevail/Lilly, Sparks Therapeutics, Uniqure, Exegenesis, Astellas, Freeline, Team Sanfilippo. She receives grants/research support from Chiesi, Sanofi, Takeda, Prevail/Lilly, Spark Therapeutics, Amicus, Freeline, Sangamo, Cyclo, Odorsia, DMT, Homology, Protaliz. She is on the speaker bureau for Sanofi, Takeda, Amicus, ChiesiDr. Kamath is on the Advisory Board for Spur Therapeutics and Intrinsic Therapeutics. He is also a consultant for Sanofi, Shire and Takeda.  Mitigation of Relevant Financial RelationshipsAffinityCE adheres to the ACCME's Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CME activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity. A non-conflicted reviewer resolved conflicts of interest for presenting faculty with relevant financial interests through peer review of content.Learning ObjectivesDescribe the role of the orthopedic surgeon in the team approach to careDescribe best practices to monitor bone abnormalities in persons with LDsDescribe best practices to treat bone abnormalities in persons with LDsDescribe research trends in bone abnormalities in persons with LDsPhysiciansThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.Physician AssistantsThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physician Assistants should claim only the credit commensurate with the extent of their participation in the activity.NursesContinuing Nursing Education is provided for this program through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation (ANCC). This activity provides a maximum of 1 hours of continuing nursing education credit. Nurse PractitionersThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Nurse practitioners should claim only the credit commensurate with the extent of their participation in the activity.Genetic CounselorsCategory 2 CEUThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credit™. Genetic counselors should claim only the credit commensurate with the extent of their participation in the activity.Other ProfessionalsAll other health care professionals completing this continuing education activity will be issued a statement of participation indicating the number of hours of continuing education credit. This may be used for professional education CE credit. Please consult your accrediting organization or licensing board for their acceptance of this CE activity.Commercial Support Support for this educational activity was provided by Takeda and Ultragenyx. Participation CostsThere is no cost to participate in this activity.CME InquiriesFor all CME policy-related inquiries, please contact us at ce@affinityced.com.Send customer support requests to cds_support+ldrtc@affinityced.com.

Quelle étape en Corse pour cette 50e édition d'un BikingMan. Axel Carion, entouré de son équipe, avait bien préparé son parcours. Aucun problème à noter durant toute cette semaine, avec toujours le même dévouement et la merveilleuse bienveillance des fameux Race Angels. C'est d'ailleurs les m^mes mots qui reviennent dans la bouche des coureurs : merci et bravoRecord de l'épreuve battue, avec 50 % des participants, dont c'était un premier BikngMan. Classement final Louis Défaut – 1er en 45h12minSimon Scodavolpe – 2e en 50h17minSimon Savre – 3e en 52h30minLorris Pasquier – 4e en 54h45minBenjamin Bodot – 5e en 56h10minDiane Servettaz la Savoyarde, s'est distinguée en franchissant la ligne d'arrivée en 72h38min, vainqueur chez les femmes.Nous nous sommes baladés au milieu des inscrits, lors de la journée des contrôles des vélos, la veille du départ. Ils ont tous le sourire, un peu stressés, mais heureux de participer à cette manche du Championnat du Monde d'ultra distance.Hébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

durée : 00:03:58 - Dormir dans une paillourte ou une cyclo-cabane en sud Finistère

This CME program provides information on best practices to manage children with lysosomal disorders who have been identified by newborn screening. WIth the wide range of symptoms and severities that present for these rare conditions, it is not always certain when the best time to start treatment is in these patients.Continuing Education InformationThis continuing education activity is provided by AffinityCE and the Lysosomal and Rare Disorders Research and Treatment Center (LDRTC). This activity provides continuing education credit for physicians. A statement of participation is available to other attendees.To obtain credit, visit https://checkrare.com/learning/p-transforming-clinical-outcomes-with-early-treatment-of-lysosomal-disorders/ Faculty and DisclosuresAffinityCE staff, LDRTC staff, planners, and reviewers, have no relevant financial relationships with ineligible companies to disclose. Faculty disclosures, listed below, will also be disclosed at the beginning of the Program.Ozlem Goker-Alpan MDFounder and CMO, Lysosomal & Rare Disorders Research & Treatment CentersDr. Goker-Alpan is on the Advisory Board/Consultant for Chiesi, Takeda, Sanofi, Prevail/Lilly, Sparks Therapeutics, Uniqure, Exegenesis, Astellas, Freeline, Team Sanfilippo. She receives grants/research support from Chiesi, Sanofi, Takeda, Prevail/Lilly, Spark Therapeutics, Amicus, Freeline, Sangamo, Cyclo, Odorsia, DMT, Homology, Protaliz. She is on the speaker bureau for Sanofi, Takeda, Amicus, ChiesiDavid F. Kronn MDAssociate Professor of Pathology and Pediatrics                                                New York Medical CollegeDr. Kronn is on the Advisory Board for Sanofi. He is also on the speaker bureau for Sanofi. He receives research funding from Sanofi.Uma Ramaswami FRCPCH, MDRoyal Free London Hospitals & Genetics and Genomic Medicine, University College LondonDr. Ramaswami is on the Advisory Board for Amicus, Chiesi, Sanofi and Takeda. She receives research grants from Chiesi and Intabio.Liz Jalazo MDAssistant Professor of Pediatrics and GeneticsUniversity of North Carolina at Chapel HillDr. Jalazo is on the Advisory Board for Sanofi and Ionis. Lindsay Torrice MSN, CPNP-PC MDAssistant Professor of PediatricsUniversity of North Carolina at Chapel HillMs. Torrice has no financial relationships to disclose.Mitigation of Relevant Financial RelationshipsAffinityCE adheres to the ACCME's Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CME activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible companies. All relevant financial relationships for faculty were mitigated by the peer review of content by non-conflicted reviewers before the commencement of the activity.Learning ObjectivesAt the end of this activity, participants should be able to:•     Cite the importance of early diagnosis and treatment of lysosomal storage disorders•     List the guidelines for the early treatment of LDs and enhanced integration of newborn screening programs•     Identify key research gaps and priorities and strengthen collaboration among researchers and healthcare professionals•     List the educational resources and support programs for familiesPhysiciansThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.Other ProfessionalsAll other healthcare professionals completing this continuing education activity will be issued a statement of participation indicating the number of hours of continuing education credit. This may be used for professional education CE credit. Please consult your accrediting organization or licensing board for their acceptance of this CE activity.Commercial SupportThis activity was supported by educational grants from Takeda, Sanofi, and Chiesi.Participation CostsThere is no cost to participate in this activity. CME InquiriesFor all CME policy-related inquiries, please contact us at ce@affinityced.com.Send customer support requests to cds_support+ldrtc@affinityced.com.

Avant toute chose, sachez que la semaine du vélo commence ce 24 mars à Liège. Au programme jusqu'au 30 : des projections, conférences, tests vélo, formations, ballades au coeur de la ville... et le petit dej offert sur les pistes cyclables ce matin pour lancer cette première édition ! 3 idées remarquées à Bike Brussels : Le vélo cargo modulable Moduleo : ce vélo est doté d'une roue avant et de deux roues arrières. Entre ces roues, on peut placer un adulte, des enfants, un caisson pour transporter jusqu'à 70 kg de matériel. Et l'idée a même été remarquée par les sapeurs-pompiers... Ozo, un kit pour transformer son vélo classique en vélo avec assistance électrique : les avantages sont à la fois financiers et écologiques. La micro-caravane pour vélo Jabiru : il s'agit d'une tente gonflable qui se gonfle au-dessus d'une remorque vélo. A louer à partir d'une trentaine d'euros par jour pour voir si le concept vous plait.Vous aimez ce contenu ? Alors n'hésitez pas à vous abonner, à lui donner des étoiles et à partager ce podcast autour de vous. Ça nous aide à nous faire connaitre et à essaimer les idées constructives qui rendent le monde plus joli !Une chronique signée Leslie Rijmenams à retrouver (aussi) sur Nostalgie et www.nostalgie.be.

Dans ce film immersif et authentique, Adrien Leroux vous plonge à seulement 22 ans dans le BikingMan Sri Lanka : une épreuve gravel du championnat du monde d'ultracyclisme. L'objectif : parcourir 1 000 km en total autonomie au cœur de la jungle sri lankaise, le tout en moins de cinq jours. Eléphants, serpents, varans… Adrien pédale parmi une faune dangereuse et inhospitalière. Certaines rencontres dont l'étudiant en journalisme se souvient encore. Le Sri Lanka est une véritable fournaise : les températures atteignent parfois les 45 °C et les 90 % d'humidité rendent l'air irrespirable. Des conditions dantesques qui ont poussé le jeune ultracycliste à s'arracher et atteindre ses limites, au bord de l'épuisement. Des plages paradisiaques de l'océan indien aux champs de thé perchés à 2 500 mètres d'altitude, Adrien vous emmène dans une aventure rythmée et haletante. Plus qu'une performance sportive, la course est une invitation à la rencontre et à la découverte d'un peuple d'une bienveillance sans égale. Adrien le dit lui-même : « J'avais l'impression d'être un cyclonaute voyageant de planète en planète à la rencontre d'une culture radicalement différente de la nôtre mais incroyablement riche ». Franchira-t-il la ligne d'arrivée à temps ?Hébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

Itt a hetedik Vakfolt díjátadó. András és Péter állandó műsorvezetőtársaként visszatér Mikó László azaz CyClo. Megtárgyalják a 2025-ös Oscar-díjra jelölt filmeket, színészeket, írókat, rendezőket, esélyeket latolgatnak, és persze hagyományosan kiosztják a Vakfolt saját díjait is, saját jelöltlistával. Az adás a hétvégén a Vakfolt Extrában folytatódik további kategóriákkal. Az alábbi kategóriákat hallhatjátok ebben az adásban: Férfi mellékszereplő Női mellékszereplő Egészestés animációs film Idegen nyelvű film Adaptált forgatókönyv Eredeti forgatókönyv Rendezés Férfi főszereplő Női főszereplő Legjobb film A Vakfolt Extrában hallgathatjátok a legjobb filmzene, legjobb vizuális effektusok, és a többi Oscar-kategóriát, valamint a Vakfolt saját kategóriáit, mint a legjobb alakítások rossz filmekben, a legjobb állati alakítások, és így tovább. Ha tetszett az adásunk, támogass bennünket a Vakfolt Extrával! Csatlakozz a Facebook-csoportunkhoz is! Mostantól Vakfolt logós pólót és egyéb kellékeket is szerezhetsz magadnak a webshopunkból! További linkek A Vakfolt podcast Facebook oldala A Vakfolt podcast az Instagramon Vakfolt címke a Letterboxdon A Vakfolt podcast a YouTube-on A Vakfolt podcast a YouTube Music-on A Vakfolt podcast a Spotify-on A Vakfolt podcast a Google podcasts oldalán A Vakfolt az Apple podcasts oldalán A főcímzenéért köszönet az Artur zenekarnak Emailen is elértek bennünket: ezitt@vakfoltpodcast.hu  

Tous les matins à 7h10, Alex nous fait faire le tour du monde avec des histoires incroyables et vraies !

Tous les matins à 7h10, Alex nous fait faire le tour du monde avec des histoires incroyables et vraies !

Tous les matins à 7h10, Alex nous fait faire le tour du monde avec des histoires incroyables et vraies !

Nouvel équipier de Wout van Aert à la Visma | Lease a bike et l'un des meilleurs ennemis d'Arnaud De Lie dans les sprints en bosse, Axel Zingle nourrit de nombreuses ambitions suite à son transfert dans l'une des meilleures équipes du monde.

Ce week-end, Mathieu van der Poel et Fem ven Empel vont remettre leur titre mondial en jeu, lors des Championnats du monde de cyclo-cross en France, à Liévin. Avant ce grand rendez-vous, Matthieu, Anselme (abzh35), Geoffrey (darth-minardi) et Johann (bullomaniak) font dans ce podcast Chasse-Patate le bilan de la saison, qui a notamment vu Michael Vanthourenhout et Lucinda Brand remporter la Coupe du monde. https://www.youtube.com/watch?v=LwrksA6Dpg4 Programme 0:00 - Introduction 1:49 - Une saison sur une bonne note ? 31:32 - Le bilan chez les hommes 53:32 - Le bilan chez les femmes 1:01:19 - Les pronos pour les Mondiaux 1:15:39 - Conclusion

Bienvenue dans ce nouvel épisode d'En Roue Libre présenté par Gordon De Winter, et accompagné de Julien Gillebert, Fred Amorison. Notre invité est Clément Horny, coureur de VTT et de cyclo ! Au programme : un petit bilan de la saison de cyclo-cross en cours, et une préface des championnats de Belgique de cx. 

In deze aflevering van Z 7 op 7:Kledingketen JBC wint de prestigieuze Mercuriusprijs, een van de belangrijkste prijzen in de Belgische retail. Ze behaalden de prijs voor hun tweedehandsconcept ‘Op-Nieuw'. Een tweedehandswinkel met ingezamelde kinder- en babykleding van JBC. En zo zijn er nu al drie.  De outdoor spinning keten Cyclo Studio haalt een nieuwe investeerder binnen: Jeroen De Wit, oprichter en CEO van software Teamleader. Het jonge bedrijf telt momenteel vijf vestigingen, maar wil de komende jaren sterk groeien.En het was uitkijken naar de impact van het einde van het fiscale gunstregime voor auteursrechten, waarop onder andere heel wat programmeurs beroep deden. Uit een onderzoek van Hudson blijkt dat de werkgevers dat netto-inkomstenverlies niet hebben kunnen compenseren.

Hoy te traigo un episodio que te va a tener enganchada, de principio a fin. ¿Qué cómo lo sé? Porque así estaba yo mientras escuchaba a nuestra invitada, Paloma Alma.Paloma es la fundadora de CYCLO, una marca que empezó con 26 años y que ha conseguido escalar y posicionar como referente en el sector, gracias a las claves que nos comparte a continuación.Así que muy atenta, porque este episodio es de los buenos.¡Qué lo disfrutes! NOTAS DEL PODCAST:https://yoemprendedora.es/de-mentalidad-emprendedora-a-empresaria-con-paloma-alma/ 

De 12 à 14h du lundi au samedi, et de 13h à 15h le dimanche, vivez le début de l'étape en direct. François Pinet, Simon Dutin, Ludovic Duchesne, Yohan Bredow, Frederic Brindelle et Romain Asselin reviennent également sur les faits marquants de l'étape de la veille et présentent les enjeux de l'étape du jour. Et pour les accompagner, un consultant de choix : Jérôme Pineau, membre de la Dream Team RMC.

Suscríbete y activa las notificaciones para estar al tanto de los episodios de la 5ª temporada.Suscríbete a nuestra newsletter en https://www.luminiscenciadeltalento.com/ y descubre cómo potenciar tu propia luminiscencia.Súmate a la conversación en Instagram:https://www.instagram.com/luminiscenciadeltalentohttps://www.instagram.com/tanialasanta/Cada lunes a las 15:00h un nuevo episodio. ********************************Paloma Alma es una mujer luminiscente, empresaria en serie en el sector de la menstruación: fundadora de Cyclo, de Menstruall y de varios proyectos relacionados con el ciclo menstrual.Su historia nos permite hacer el viaje completo desde la fundación de una empresa hasta la salida de ella, así como la búsqueda y reinvención de ti misma más allá de tu marca.Puedes encontrar a Paloma Alma en:https://www.instagram.com/palomaalma__/https://www.instagram.com/menstru_all/https://www.instagram.com/conunpardeovarios_podcast/https://www.palomaalma.com/https://www.menstruall.com/********************************Expande tu carrera y tu negocio a través de la Luminiscencia del Talento®️: el método con base científica que te lleva a tu expansión individual y a nuestra expansión colectiva a través de tu luminiscencia. Tu luminiscencia es tu capacidad única de emitir luz a raíz de las circunstancias vitales que la han activado. Al contrario del brillo, que depende de la mirada externa, tu luminiscencia te devuelve tu poder personal.En este podcast descubrirás cómo liberar tu luminiscencia y entenderás este fenómeno en profundidad a través episodios prácticos y de entrevistas a personas que han hecho grandes transformaciones en su vida desde su luminiscencia. De la mano de Tania Lasanta, mentora de mujeres líderes y fundadora de Luminiscencia del talento®️. A través de sus programas, mentorías y servicios, ayuda a mujeres líderes a ocupar su espacio y alcanzar la facturación y posicionamiento que desean, en https://www.tanialasanta.com/

At 46, Kateřina Nash has been racing bikes for three decades and continues to compete at the highest level. Originally from the Czech Republic, she competed in skiing throughout her early life, even competing in two Winter Olympics before discovering a love for mountain biking. She was part of the first cohort of the groundbreaking LUNA Pro Team in 2002, and stayed with the team for more than two decades. In that time, she won seven Cyclo-cross World Cups, competed in three Summer Olympics, and, for the past few years, has served as a Vice President of the UCI and President of the Athletes' Commission.Payson caught up with Kateřina in Bentonville last week to talk about growing up behind the Iron Curtain, moving to the U.S. on a ski scholarship, and why she still can't believe she got to sign with the LUNA Pro Team. She talks about how her training has changed as she's gotten older, why she still loves professional racing, and how she's managed to stay so fast for so long. She also talks about how her roles within the UCI came about, and the phone call she received last year that is an athlete's worst nightmare. Use code PAYSON20 for 20% off at voler.com through May 30th.Instagram: @theadventurestacheYouTube: Payson McElveen

Humans have had an insatiable appetite for inhibiting production of prostaglandins for centuries! This series delves into the history of aspirin and NSAIDs, looking at the understanding of the prostaglandin pathway. ·       Intro 0:12 ·       In this episode 0:23 ·       What are NSAIDs? 0:53 ·       Prostaglandins 5:50 ·       What are prostaglandins? 7:19 ·       Where do prostaglandins come from? 8:45 ·       So, what do we do with prostaglandins? 13:15 ·       How did they figure out prostaglandins? 13:55 ·       Naming the prostaglandin 21:25 ·       Phospholipids 24:46 ·       Arachidonic acid 25:28 ·       Arachidonic acid into prostaglandins: how do you prove it? 26:32 ·       How does arachidonic acid turn into prostaglandins? 27:27 ·       Cyclo-oxygenase 28:36 ·       mRNA and COX-2 32:50 ·       On the next episode 35:55 ·       Summary 36:38 ·       Thanks for listening 37:49 Disclosures: Brown reports no relevant financial disclosures. We'd love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum. References: Botting RM. Pharmacol Rep. 2010;doi:10.1016/s1734-1140(10)70308-x. Flower RJ. Br J Pharmacol. 2006;doi:10.1038/sj.bjp.0706506. Flower RJ. Br J Pharmacol. 2019;doi:10.1111/bph.14588. Kurzrok R, et al. Exp Biol Med. 1930;doi:10.3181/00379727-28-5265. https://www.nobelprize.org/prizes/medicine/1970/euler/biographical/. von Euler US. J Physiol. 1936;doi:10.1113/jphysiol.1936.sp003433.

Paloma Alma es una crack. Quizá la conoces porque en 2016 empezó el proyecto CYCLO, siendo pionera en romper tabúes sobre la menstruación, el dolor, el ciclo hormonal, fértil y creativo de las mujeres, y muchas más cosas. También publicó un libro (llamado tb CYCLO), y ha tenido 2 hijos. Compartió su primer relato de parto en el episodio 45, y un par de años después vuelve al podcast para hablar del nacimiento de su segundo bebé en el episodio 154. Paloma nos habla de cómo se cuidó durante el embarazo (y qué tuvo que hacer para poder permitírselo económicamente), cómo de distinta fue la segunda experiencia, qué pasó durante su parto y también después. Además, como es una mujer tan creativa y visionaria, ha empezado este 2024 su siguiente etapa profesional con un proyecto maravilloso: una comunidad y directorio donde mujeres como tú y como yo pueden encontrar todo tipo de profesionales especialistas en la salud sexual, menstrual y reproductiva femeninas. Te aconsejo que le eches un vistazo en https://www.menstruall.com/ Bienvenida al podcast, espero que disfrutes este episodio tanto como yo. ¡CLICA PLAY y EMPEZAMOS! --- Planeta Parto es el podcast en el que hablo con mujeres sobre sus relatos de parto y la manera única en la que dieron a luz a sus bebés. Todas las historias importan: los partos vaginales, los fisiológicos, los inducidos, los hospitalarios, los que ocurren en casa, los auto-gestionados, las cesáreas, los intrumentalizados, los salvajes, los complicados, los respetados, los arrebatados. Todos. Escuchar el podcast, con la biblioteca de más de 140 episodios de todo tipo, ayuda muchas mujeres a informarse, sentirse preparadas, ganar seguridad, y entender de qué va realmente parir a un bebé - o curar una herida antigua. Si te gusta el programa, ¡suscríbete! Acompáñame cada semana y escucha relatos emocionantes, conmovedores e informativos que te ayudarán a conocer y vivir el parto de otra manera. Por último... ¡no dudes en escribirme! Me encantará saber de ti, quién eres, por qué escuchas este programa o si te ha ayudado. Soy Isa y me encontrarás en en instagram bajo @planetaparto.podcast (https://instagram.com/planetaparto.podcast) o por email en isa@planetaparto.es

Chris lands in a snowy Budapest in the early hours of the morning - tired but hungry for answers...If you have any information that might aid our investigation, send them to motordoping@gmail.com.Do make sure to subscribe to Ghost In The Machine, so that you don't miss an episode.-------In January 2016,19-year-old Belgian cyclist Femke van den Driessche was caught with a collection of wires, motors and batteries buried deep inside her bike at the Cyclo-cross World Championships.She was then suspended for six years and bore the wrath of global media as the only rider ever to be banned by The Union Cycliste Internationale (UCI) for having a motor in her bike, despite numerous previous suspicions of other competitive cyclists that have never been confirmed or disproved.Eight years later, Chris is on a mission to reveal the truth around motors in cycling as he peers beneath the surface of sports' most incredible discovery...and beyond. Hosted on Acast. See acast.com/privacy for more information.

Az idei már a hatodik Vakfolt díjátadó, és András és Péter állandó műsorvezetőtársaként visszatér Mikó László azaz CyClo. Megtárgyalják a 2024-es Oscar-díjra jelölt filmeket, színészeket, írókat, rendezőket, esélyeket latolgatnak, és persze hagyományosan kiosztják a Vakfolt saját díjait is, saját jelöltlistával. Az adás hamarosan a Vakfolt Extrában folytatódik további kategóriákkal. Az alábbi kategóriákat hallhatjátok ebben az adásban: Férfi mellékszereplő Női mellékszereplő Egészestés animációs film Idegen nyelvű film Adaptált forgatókönyv Eredeti forgatókönyv Rendezés Férfi főszereplő Női főszereplő Legjobb film A Vakfolt Extrában hallgathatjátok a legjobb filmzene, legjobb vizuális effektusok, és a többi Oscar-kategóriát, valamint a Vakfolt saját kategóriáit, mint a legjobb alakítások rossz filmekben, a legjobb állati alakítások, és így tovább.  Ha tetszett az adásunk, támogass bennünket a Vakfolt Extrával! Csatlakozz a Facebook-csoportunkhoz is! Mostantól Vakfolt logós pólót és egyéb kellékeket is szerezhetsz magadnak a webshopunkból! További linkek A Vakfolt podcast Facebook oldala A Vakfolt podcast az Instagramon A Vakfolt podcast a Twitteren Vakfolt címke a Letterboxdon A Vakfolt podcast a YouTube-on A Vakfolt podcast a YouTube Music-on A Vakfolt podcast a Spotify-on A Vakfolt podcast a Google podcasts oldalán A Vakfolt az Apple podcasts oldalán A főcímzenéért köszönet az Artur zenekarnak András az X-en: @gaines_ Péter az X-en: @freevo Emailen is elértek bennünket: ezitt@vakfoltpodcast.hu  

Una de esas verdades, con las que convivimos en silencio a la hora de sacar adelante nuestras empresas siendo mujer, es el batiburrillo mental, físico y emocional que nos provoca el ciclo menstrual. Según la invitada de este episodio: reconciliarnos con nuestro ciclo menstrual nos permite vivirlo en positivo y trabajar mejor. Esta semana en FocusPreneur Podcast

Host Chris Marshall-Bell speaks to senior figures in cycling - are the authorities doing enough to safeguard the sport? This podcast is now a live investigation. We've received multiple tipoffs so far - but if you have any information that might aid our investigation, send them to motordoping@gmail.com. Do make sure to subscribe to Ghost In The Machine, so that you don't miss an episode. We'll be back in a few weeks, as Chris heads to Istanbul for answers...-------In January 2016,19-year-old Belgian cyclist Femke van den Driessche was caught with a collection of wires, motors and batteries buried deep inside her bike at the Cyclo-cross World Championships.She was then suspended for six years and bore the wrath of global media as the only rider ever to be banned by The Union Cycliste Internationale (UCI) for having a motor in her bike, despite numerous previous suspicions of other competitive cyclists that have never been confirmed or disproved.Eight years later, Chris is on a mission to reveal the truth around motors in cycling as he peers beneath the surface of sports' most incredible discovery...and beyond. Hosted on Acast. See acast.com/privacy for more information.

Host Chris Marshall-Bell finds himself outside the home of the Van den Driessches...-------In January 2016,19-year-old Belgian cyclist Femke van den Driessche was caught with a collection of wires, motors and batteries buried deep inside her bike at the Cyclo-cross World Championships.She was then suspended for six years and bore the wrath of global media as the only rider ever to be banned by The Union Cycliste Internationale (UCI) for having a motor in her bike, despite numerous previous suspicions of other competitive cyclists that have never been confirmed or disproved.Eight years later, Chris is on a mission to reveal the truth around motors in cycling as he peers beneath the surface of sports' most incredible discovery...and beyond. Hosted on Acast. See acast.com/privacy for more information.

Host Chris Marshall-Bell continues his investigation on the cobbled streets of Aalst - which takes quite the turn...-------In January 2016,19-year-old Belgian cyclist Femke van den Driessche was caught with a collection of wires, motors and batteries buried deep inside her bike at the Cyclo-cross World Championships.She was then suspended for six years and bore the wrath of global media as the only rider ever to be banned by The Union Cycliste Internationale (UCI) for having a motor in her bike, despite numerous previous suspicions of other competitive cyclists that have never been confirmed or disproved.Eight years later, Chris is on a mission to reveal the truth around motors in cycling as he peers beneath the surface of sports' most incredible discovery...and beyond. Hosted on Acast. See acast.com/privacy for more information.

2023 végén kiválasztjuk a kedvenc filmjeinket az idei bemutatók közül. A hagyományoktól eltérően ezúttal nem top 10-es, hanem top 5-ös listával jelentkezünk, ám nem kell attól tartanotok, hogy kevesebb érdekes filmről fogtok hallani, ugyanis ezúttal nemcsak András és Péter, hanem állandó vendégeink-műsorvezetőtársaink, Gyöngyösi Lilla, Rácz Viktória, és Mikó László azaz CyClo is csatlakoztak az adáshoz, és egészen különleges filmes gyöngyszemekkel készültek. Ennek köszönhetően minden eddiginél hosszabb, három óra fölötti toplistázós adással érkeztünk. Igyekeztünk olyan filmeket választani, amelyek a magyar mozipremier-naptár szerint, valamint a streamingen és VOD-n történő megjelenésünk szerint 2023-ra estek, de így is lesz néhány olyan helyezett, amelyeket a magyar nézők döntő többsége csak 2024-ben láthat majd, csak nekünk volt szerencsénk elcsípni azokat fesztiválokon. Így tekinthetitek az adásunkat ajánlónak is a januári-februári mozinaptárra.  Ha tetszett az adásunk, támogass bennünket a Vakfolt Extrával! Csatlakozz a Facebook-csoportunkhoz is! Mostantól Vakfolt logós pólót és egyéb kellékeket is szerezhetsz magadnak a webshopunkból! További linkek A Vakfolt podcast Facebook oldala A Vakfolt podcast az Instagramon A Vakfolt podcast a Twitteren Vakfolt címke a Letterboxdon A Vakfolt podcast a YouTube-on A Vakfolt podcast a Spotify-on A Vakfolt podcast a Google podcasts oldalán A Vakfolt az Apple podcasts oldalán A főcímzenéért köszönet az Artur zenekarnak András az X-en: @gaines_ Péter az X-en: @freevo Emailen is elértek bennünket: ezitt@vakfoltpodcast.hu  

We're getting to the end of the Life in the Peloton season, and I've saved a special episode for this week. Just as the long road season winds down, the winter cyclo-cross season is firing up for the year. And you might be asking – what exactly is cyclo-cross racing? To learn a little bit about the sport and its history, I've found someone who can talk me through it. But it's not just any old person, I've gone and found the best in the business, the undisputed G.O.A.T – Sven Nys.   Sven has an incredible ability to teach and talk about cyclo-cross to literally anyone – from kids right up to pros, and he does it in such a humble and entertaining way. He's so good at it because he is an absolute champion and a true giant of the sport, the best to have ever thrown a leg over a cyclo-cross bike – or I should probably say to have thrown a cyclo-cross bike over his shoulder.   An incredibly dominant rider throughout his career, Sven won literally everything of importance – earning him the nicknames The Cannibal, and the Eddie Merckx of cyclo-cross. At his peak in the 2004 – 2005 season, he did something that no other cyclo-cross rider has ever done, when he took out the National and World Championships, won the Superprestige, and the Gazet van Antwerpen, and finished the season ranked number one in the UCI rankings and the World Cup. He is the only cyclo-cross rider to have achieved this even once, and he went close to repeating the incredible feat in the following season – only just falling short when he crashed in the final lap of the World Championships.   It's an absolute privilege to have Sven join me on Life in the Peloton today, I hope you enjoy the listen!   Cheers,   Mitch

Monica Wong and Quynh Nguyen are the founders of a Little Green Cyclo. I met Monica and Quynh back in the day in 2010 when they first started with their first Vietnamese food truck serving delicious Banh Mi and various dishes. Monica grew up on the East Coast where her family owned one of the first Chinese restaurants in downtown Boston. Monica worked many years in finance, before deciding to get back in the food business. Quynh grew up in Saigon, Vietnam and spent most of her childhood playing table tennis for her country's National Team. After moving to the states working various jobs and Quynh then opened her own a Cajun restaurant in San Jose,CA. Quynh then joined forces with Monica and started Little Green Cyclo.After 13 years of business, Monica and Quinn have created not only one of the original Vietnamese Food trucks in the San Francisco Bay Area; but also now have a full service bistro and their own brand of award winning ready-to-drink Vietnamese Coffee. I really enjoyed sitting down with Monica and Quynh after being a customer for so many years. It was great to have them their story and appreciate them for all their support in my journey as well. Little Green Cyclo https://www.littlegreencyclo.comLGC Vietnamese Coffeehttps://coffeelgc.com Full Bio , Links and Show Notes:https://www.foodoriginspodcast.com/podcast-episode-30Support the show

durée : 00:04:17 - Vizo sport - par : Alex VIZOREK - Alex Vizorek nous parle d'un sport à mi-chemin entre le Tour de France et la bataille de Verdun.

This month, The Cycling Podcast Féminin team get what they wished for: a fiercely fought battle between two teammates. Lotte Kopecky and Demi Vollering gunned it out at Strade Bianche with the Dutchwoman eventually crowned the victor after a tense photo finish. Despite being pipped into second, the Italian classic marked yet another chapter in Kopecky's extraordinary early season in which she has never finished lower than runner-up.  Rose Manley, Orla Chennaoui and Lizzy Banks discuss the race and its fallout, including the controversial disqualification of Kristen Faulkner for the wearing of a continuous glucose monitor.  Rose also speaks to Puck Pieterse, one of the unlikely stars of Strade Bianche. Cyclo-cross racer Pieterse finished fifth in her first ever Women's World Tour road race. She explains her approach to having fun on the bike and why we won't be seeing her at any more road races this season. The team also talk about a less acrimonious team one-two finish at Trofeo Alfredo Binda. Last month's interviewee Shirin van Anrooij took the win there, followed by her Trek-Segafredo teammate Elisa Balsamo. Orla closes the show with a beautiful tribute to our deeply missed friend Richard Moore, who passed away a year ago. The Cycling Podcast is supported by Supersapiens and Science in Sport. Follow us on social media: Twitter @cycling_podcast Instagram @thecyclingpodcast Sports Podcast Awards shortlist The Tour d'Écosse series has been shortlisted for the 2023 Sports Podcast Awards. It's a public vote so it's over to you. If you enjoyed the series and would like to vote, you can do so here. You need to create an account to vote and we are in the ‘wilderness' category. The 11.01 Cappuccino Our regular email newsletter is now on Substack. Subscribe here for frothy, full-fat updates to enjoy any time (as long as it's after 11am). Supersapiens Supersapiens is a continuous glucose monitoring system that helps you make the right fuelling choices. See supersapiens.com Science in Sport The Cycling Podcast has been supported since 2016 by Science In Sport. World leading experts in endurance nutrition. Go to scienceinsport.com to see the whole range. Join the Science In Sport Classic 100 Challenge on Strava. Ride 100km between March 18-31 for a chance to win a trip of a lifetime to the finish of Paris-Roubaix. MAAP The Cycling Podcast x MAAP collection is available now. Go to maap.cc to see the full MAAP range. D Vine Cellars To order The Cycling Podcast Highlights case, or any of the cases commemorating the 2022 Grand Tours visit dvinecellars.com Friends of the Podcast Sign up as a Friend of the Podcast at thecyclingpodcast.com to listen to more than 60 exclusive episodes. The Cycling Podcast is on Strava The Cycling Podcast was founded in 2013 by Richard Moore, Daniel Friebe and Lionel Birnie.

In 2000, female riders were able to take part in the cyclo-cross world championship for the first time. There has been a men's event since 1950, but took another half century for female riders to be allowed to take part. Cyclo-cross involves races on grassland and sand, which includes steep gradients and often sees riders forced to jump off and run with their bikes across muddy sections of the course. Matthew Kenyon has been talking to Dutch rider Daphny van den Brand about the sport, her campaign and that first ever global showpiece in the Dutch town of Sint Michielsgestel. (Photo: Daphny van der Brand. Credit: Getty Images)

durée : 00:04:03 - Vizo sport - Alex Vizorek nous parle d'un sport à mi-chemin entre le Tour de France et la bataille de Verdun.

Hey Y'All!  It's been a while since we've updated you a bit on the podcast so we start today's recording with a quick update.  Then we hope on the line with Sara Qiu, the Spanish cyclo-tourist who we talked with in episode 38. She's crossed over onto the continent of Asia and is riding through Turkey at the moment.  It was fun to hear how she's grown as a cyclo-tourist and as a person!   You can hear and see much more of Sara's story on her YouTube channel -  Journey From the Road.  She posts back and forth in Spanish and English.  Keep up with her @journeyfromtheroad on Instagram as well!   You can follow us @theinfatuasianpodcast on Instagram and Facebook.  Email us at infatuasianpodcast@gmail.com and we'll read your message on the air! Thanks for listening! Our Theme: “Super Happy J-Pop Fun-Time” by Prismic Studios was arranged and performed by All Arms Around  #cyclotourist #journeyfromtheroad #asianpodcast #asian #asianamerican #infatuasian #iinfatuasianpodcast #aapi #veryasian #asianamericanpodcaster #representationmatters

Cyclo-cross returns to Centennial Park in Fayetteville, Arkansas October 14th thru the 16th. OZCX is a family and spectator friendly event culminating with the UCI Cyclo-cross World Cup. The event partners with Arkansas Children's Hospital - Northwest to raise funds and awareness for pediatric care across NWA.