Podcasts about forensic chemistry

At the beginning of the 1900s, New York City was in turmoil. Prohibition loomed, outbreaks of typhoid and an influenza pandemic had people on edge, and the city was steeped in corruption. One of the many consequences of that corruption was a completely inept coroners office. Instead of having trained medical examiners work out the causes of sudden and suspicious deaths, New York City coroners were politically appointed. And they didn't have the slightest idea of how to do a thorough autopsy. They were sign painters and milkmen and funeral home operators and people who had done favors for the party. They bungled the cause of death so consistently and so dramatically that the police and the district attorney's office told coroners to stay away from their crime scenes. This was a horrific situation, unless you were a poisoner. In January, 1915, New York City's government released a report saying that murderers were easily escaping justice and that “skillful poisoning can be carried on almost with impunity.”In this episode of Tiny Matters, Sam and Deboki chat with Pulitzer Prize-winning journalist Deborah Blum, the author of The Poisoner's Handbook, about the rise of forensic toxicology in the United States. Listeners will be taken on a journey through some of the disturbing poisoning cases of the time that helped lay the groundwork for the field — with a focus on arsenic, radium and cyanide — and the pivot role medical examiner Charles Norris and chemist Alexander Gettler played in restoring public safety and finally stopping poisoners in their tracks. We have a YouTube channel! Full-length audio episodes can be found here. And to see video of Sam, Deboki, and episode guests, check out Tiny Matters YouTube shorts here!We love our listeners and we want to bring you more of what you like! Head to bit.ly/tinypodsurvey to give us feedback and help us make Tiny Matters even better. The survey should take no more than 5-10 minutes to fill out. Your motivation? Filling out the survey will enter you into a Tiny Matters mug raffle! Links to the Tiny Show & Tell stories are here and here. Pick up a Tiny Matters mug here! All Tiny Matters transcripts are available here.

Welcome back to another season of LNXdance with your Co-Hosts, Marcus & Mari!Join us for this super inspiring episode as we have the privilege of interviewing the one and only Dr. Bruno Rodriguez, Ph.D. Check out his biography below and listen in to find out how he juggles it all: doctoral degree in Microbiology, cross-genre training, AND international career as a dancer, performer, and educator!Born and raised in Puerto Rico, Bruno Rodriguez began his salsa training at the age of 9 under the direction of Julie Mayoral, Nalliene Velez, and Jayson Molina. He won his first junior world championship at the age of 11 and started training in jazz at the age of 14. After winning his first soloist professional world title in 2014, Bruno moved to Penn State University to pursue a Master's in Forensic Chemistry, where he also choreographed and directed the Performance Team of the Penn State Ballet Club. He then moved to New York City in 2017 to pursue his academic and salsa dancing career. Bruno won his second soloist world title in 2018 at the La Negra International Championship in Spain and started his professional partnership with Karel Flores in 2018. In December 2022, Bruno earned his Ph.D. in Microbiology from the NYU School of Medicine and joined the Biology adjunct faculty of Hunter College while traveling and teaching alongside Karel Flores at multiple international salsa events.Comparte el amor  with our lovely guest by leaving a comment on this episode and letting us know what your favorite part of this chat was. We want to send a big thank you to Dr. Bruno Rodriguez for making this Sip & Chat happen and for sharing his story with us!Dr. Bruno on IG:https://www.instagram.com/thebrunorodriguez/Adjunct Professor: https://hunter.cuny.edu/ Published Article: https://www.nature.com/articles/s41467-023-38783-0LNX x FuegoDanceShoes Brand AmbassadorsAñadele Sazón by wearing Fuego Shoes! Use our code LNX10 for 10% off. Click the link to learn more!Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the Show.--Brought to you by MotionScoop Dance Corp, LNXdance Podcast is a series of conversations FOR Latinx dancers and educators BY Latinx dancers and educators. Join Mari & Marcus -M&M- as they dive deep into important topics in the dance industry and explore how being part of the Latinx community affects us, our contributions, decisions, and careers. We hope you enjoy our sip and chat, don't forget to subscribe and leave a comment with what you loved, questions and topics for next time! Follow us on our Instagram page LNXdance to interact with our community and with us.For business inquiries and to apply to be a guest, please email motionscoopinfo@gmail.com ¡Adiós! Hosts: Marcus Mantilla-Valentin & Mari VasconezSponsors: MotionScoop Dance Corp.

The Local Lens is a public health podcast going inside one community's experience with the drug epidemic. Everyone in the town of Stanton, KY sees this drug issue differently from each other, either because of their personal lives or professional roles. This show aims to showcase those different perspectives by having honest, in-depth interviews.There is a chase happening in the world of chemistry. The list of drugs and chemicals being abused is growing so fast that no one can truly keep up. We are all aware of fentanyl at this point, but what most people do not realize is that fentanyl is an umbrella-term for a whole category of drugs. The terrifying fact is this: most people are unaware of the chemical mixtures out there. If someone thinks they are taking a Xanax pill, it could very easily be a counterfeit pill made with 5 different kinds of fentanyl. It is nearly impossible for anyone to know exactly what drugs and chemicals they are buying or selling. One place that can tell what is in a drug is the Kentucky State Police's forensic lab. On this episode, chemist Rebecca Stone tells us about the changing drug landscape from a chemical perspective. This science-heavy episode is not meant to bring a level of understanding, but just a basic awareness of what is out there. These are our people, using our voices, telling our stories, because no one sees it like we do.24-Hour Crisis Line: 1-800-562 8909Visit findhelpnowky.org to find treatment options for you in Kentucky.Need help now? Call the Mountain Comp Care 24-Hour Helpline: 1-800-422-1060Learn more about the Kentucky State Police's Angel Initiative here.Keep up with The Local Lens on Facebook, Instagram (@thelocallens_podcast) or on their website.The Local Lens is sponsored by Kentucky Opioid Community Healing (from the Kentucky Rural Health Information Organization) and Powell County CARES (from the Powell County Health Department).Find Powell County CARES on social media:https://www.facebook.com/powellcountycaresInstagram: @powellcountycares

Dr Kari Pitts is a Forensic Chemist and Mineralogist in the Physical Evidence Team of ChemCentre's Forensic Science Laboratory. She holds a PhD and a Masters in Forensic Science from UWA, and a Bachelor of Science with Honours from Curtin University. Working at ChemCentre for nearing 16 years, her expertise is trace evidence; including paint, glass, gunshot residue, soils, fibres, and anything else that isn't biological, a drug or radioactive. Dr Pitts has reported over 300 cases and given expert evidence in criminal trials in Australia and New Zealand. With a passion for outreach, she was the 2016 RACI WA Bayliss youth lecturer and a 2019-20 Science and Technology Australia Superstar of STEM.   In our conversation, we talk about Kari's journey to forensic science, working with physical evidence, and how it's not quite like CSI. Show Notes: https://steampoweredshow.com/shows/kari-pitts Connect with STEAM Powered: Website YouTube Facebook Instagram Twitter Patreon Ko-Fi

In episode one of our Strengthening the Forensic Workforce season, Just Science sat down with Dr. José Almirall, a Distinguished University Professor in the Department of Chemistry and Biochemistry and Director of the National Science Foundation-funded Center for Advanced Research in Forensic Science at Florida International University, and Dr. Sarah Kerrigan, Professor and Chair of the Forensic Science Department at Sam Houston State University and Director of the Institute for Forensic Research, Training and Innovation, to discuss the inception of the Forensic Science Education Programs Accreditation Commission (FEPAC) and chemistry programs in forensic science. Built on the foundation of the Technical Working Group on Education and Training in Forensic Science, or TWGED, FEPAC became an official standing committee of the American Academy of Forensic Sciences and awarded its first accreditation in February 2004. Since then, over 50 undergraduate and master's level forensic science programs have been accredited in the United States. Listen along as Dr. Almirall and Dr. Kerrigan discuss their roles as founding members and early adopters of FEPAC, training the next generation of forensic chemists, and the importance of expanding the number of forensic science Ph.D. programs. This episode is funded by the National Institute of Justice's Forensic Technology Center of Excellence.

Dr. Theresa Stotesbury, Forensic Chemist from Ontario Tech University has been studying different aspects of blood such as time of deposition from DNA degradation, extreme temperature effects, blood substitutes, animal blood and much more!Originally aired on April 15, 2021

In this Episode I sit down again and talk with Dr. Lauryn DeGreeff.  She has complete more research since the last time we talked to her and has focused on odor mixtures.  We talk about mixture vs cocktail and debunk a few myths that exist in the K9 world. In my intro I cover the topic of FALSE ALERTS and what a 3 main causes and some ideas on how to fix them. PHD, Forensic Chemistry, Florida International University Dr. Lauryn E. DeGreeff has worked in the field of analytical chemistry in support of canine detection for more than 12 years. She received a Ph.D. in Chemistry with an emphasis in Forensic Science from Florida International University in 2010. Her research focused on the sampling, characterization, and delivery of human odor, living and deceased, for the purpose of canine detection. Following the completion of her doctorate, she worked as a research fellow at the Federal Bureau of Investigation, Counterterrorism and Forensic Science Research Unit. Her research focus was detection and determination of human scent and odor and human blood or the development / improvement of canine training aids and training methods. Dr. DeGreeff began her research at the U.S. Naval Research Laboratory in 2012 with research efforts focused on the characterization of explosives for instrumental and canine detection. She has since developed and patented a canine training tool for training on mixed odors, which has recently been brought to commercial market. Additional research has included a chemistry-based approach to studying canine olfaction for the purpose of improving canine training and informing field vapor sampling practices. Dr. DeGreeff has published numerous journal articles, holds three patents, has presented her research at numerous national and international conferences, and frequently gives educational seminars law enforcement officers and military personnel. Non Profit Shout out: Vegas Casino K9 Foundation www.vck9f.org/donate  Show Sponsors: Getxent odor tubes: www.getxent.com Sci K9 home of the TADD: www.scik9.com Precision Explosives: www.pre-exp.com Ford K9: Go check out the NEW www.fordk9.com NEW Webinars, Classes, Seminars and soon ONLINE CLASSES with 14 Instructors. Go view all our upcoming classes and seminars which now includes PUPPY COGNITION. Where is Cameron teaching? Go view the EVENTS page: https://www.fordk9.com/events/   Looking for your next TRAINED Detection dog???                   Contact us Info@fordk9.com   Go support K9s Talking Scents Podcast and buy some gear https://www.fordk9.com/product-category/hats/    

Trusting Your Gut, Growing, and Being a Leader.In this episode of The Outspoken Podcast, host Shana Cosgrove talks to Amanda O'Donohue, Chief Operating Officer (COO) and Chief Experience Officer (CXO) at Nyla Technology Solutions. Amanda discusses the value of the culture at Nyla and her journey with Shana for the past six years. She also talks about being a leader and the dynamic with her team. We get to hear a good bit of advice on trusting your gut, growing, and getting out of your comfort zone. Lastly, Amanda goes into her regrets, superpowers, and how she got away with shoving a pie in Shana's face! QUOTES “I feel like in business and in life, there's not always a right answer or wrong answer. So, you have to go with what you think is best and be okay with that.”– Amanda O'Donohue [19:36] “I think if you can't experiment and try out new things, you can't grow.”– Amanda O'Donohue [34:25] “I think there's something validating [to knowing] that you following your gut is working. You're making good decisions. I think that's the biggest thing is it's given me a lot more confidence.”– Amanda O'Donohue [54:56]   TIMESTAMPS  [00:04] Intro [02:35] Meet Amanda O'Donohue [03:59] Growing Up Wanting to be a Pharmacist [04:43] Forensic Chemistry and Trying New Things [05:44] Growing Up in Buffalo [07:02] Work During and After College [08:52] Meeting Shana [13:52] Starting at Nyla [15:28] Staying at Nyla [17:34] Before Nyla and Becoming a Leader [19:18] Figuring it Out and Team Dynamic [27:17] Moving Back Home [30:01] Culture and Experience Working at Nyla [34:49] Philanthropy at Nyla [39:03] Shoving Pie in Shana's Face! [40:22] Programs Amanda Found for Nyla [44:26] Getting a Business Coach [47:07] Amanda's Superpowers [49:35] Recruiting [50:59] Regrets and Growing [52:16] Amanda and Shana's Dynamic [54:21] Amanda's Favorite Book [55:09] Wrap Up Questions [60:39] Outro   RESOURCES https://thedailyrecord.com/leading-women/ (The Daily Record Leading Women Award) http://www.buffalo.edu/ (University at Buffalo) https://www.towson.edu/ (Towson University) https://mentholatumointment.com/ (Mentholatum) https://www.sba.gov/federal-contracting/contracting-assistance-programs/hubzone-program (HUBZone) https://disa.mil/ (DISA) https://www.riseliveweekend.com/ (Rachel Hollis Conference) https://k9sforwarriors.org/ (K9s For Warriors) https://www.habitat.org/ (Habitat for Humanity) https://www.google.com/chromebook/ (Chromebook) https://www.baltimorecityschools.org/schools/97 (Collington Square Elementary/Middle School) https://www.linkedin.com/in/joditurnerhume/ (Jodi Hume) on LinkedIn https://www.linkedin.com/in/edmullin/ (Ed Mullin) on LinkedIn https://www.baltimoreroboticscenter.com/ (Baltimore Robotics Center) https://www.linkedin.com/in/garyabonner/ (Gary Bonner) on LinkedIn https://www.pcsforpeople.org/ (PCs for People) https://www.hiringourheroes.org/ (Hiring Our Heroes (HOH)) https://www.linkedin.com/in/courtney-davis-4a186416a/ (Courtney Davis) on LinkedIn https://www.dllr.state.md.us/employment/appr/ (Maryland Apprenticeship and Training Program (MATP)) https://governor.maryland.gov/ (Governor Larry Hogan) https://www.nsa.gov/ (NSA) https://www.amazon.com/21-Irrefutable-Laws-Leadership-Anniversary/dp/0785288376 (The 21 Irrefutable Laws of Leadership: Follow Them and People Will Follow You) by John C. Maxwell   RELEVANT LINKS https://www.linkedin.com/in/amanda-o-donohue-677a6648/ (Amanda O'Donohue)  on LinkedIn https://nylatechnologysolutions.com/ (Nyla Technology Solutions) I'd love to hear from you -- your feedback is important to me and I read all of it. If you enjoyed the podcast, I hope you'll give us 5 stars. I'll be sure to thank you via email. If not, let me know what you think we should do differently. Don't forget to hit “subscribe” so you'll receive notifications about guest interviews and other topics that drop every Tuesday. Live well,

We're super excited to introduce you to Dr. Tamara King, who we will be chatting with today. Dr. King got her B.S. in Forensic Chemistry from the University of Mississippi, and a Ph.D in Pharmaceutical Sciences from the University of Florida. She then did a one year long postdoctoral fellowship at the Division of Applied Regulatory Sciences at the FDA, and is now a DMPK scientist at BMS. Learn about the career of a fascinating scientist! 

The forensic chemistry laboratory performs analyses of drugs, including controlled substances, pharmaceuticals and clandestine laboratory samples. Chemists in the section analyze evidence items and conclusively identify a controlled substance or perform sufficient analysis to determine that no controlled substances are present.

William Shirley, 10 out of 10 on the Armineh Davis Kindness Scale, left us a year ago in a pandemic to pursue his dreams in the very cold state of Michigan. Having been entirely isolated in his apartment for the year, William could not wait to catch up with his TTC family.This stuff also happens: Some of the TTC Teens made their #TTCDivaDads return to breakdown Spacegirl the Musical, coming soon. Rodney and Dana recorded TOGETHER, which meant Dana was lucky enough to try Rod’s newest cocktail…. Or was he? Cynthia performer her now iconic Mike Kilgore impression, and we all learned the importance of always saving the last one for Andy. DRINK RECIPE: To a cocktail shaker, add:2 oz white rum0.5 oz gunpowder green tea simple syrup*0.4 oz fresh lime juice0.4 oz fresh lemon juice4 drops black lemon bitters or daiquiri bitters4 drops sea salt saline solutionShake with ice. You want quite a bit of dilution from your ice, so either shake with wet ice or with some crushed ice in with your larger ice. You could also add 1/3 oz of ice-cold water to your shaker if you do not have wet ice or crushed ice available, or if you simply want more dilution to your daiquiri. Double-strain into a chilled glass. You want to double-strain in order to avoid getting small ice chips in your drink.Support TTC by going to ibelieveinTTC.comLINKS: https://www.ttcdivadads.com/ https://www.facebook.com/TTCDivaDads https://www.instagram.com/TTCDivaDads/https://www.youtube.com/channel/UCYD2...https://twitter.com/TTCDivaDadshttps://www.tiktok.com/@ttcdivadadsBio:William is originally from Austin, Texas. He first found TTC in 2017 when he auditioned for BIG RIVER. Over the next three years, he participated in three other shows: BEAUTY AND THE BEAST, SHE LOVES ME, and ROCK OF AGES. He was also the assistant stage manager for the 2019 production of THE ROCKY HORROR SHOW.William received his bachelor's degree in Forensic and Investigative Science at Texas A&M University last May, and he moved to East Lansing, Michigan in August. He is currently working on a dual degree program at Michigan State University, pursuing a masters degree in Forensic Chemistry and a PhD in Chemistry. TTC provided a constant home and friendship for William while living in BCS, and he is very thankful for the theatre and all his friends there!

Season 2 Episode 5: Smoking Gun. Jean Servais Stas, Belgian chemist extraordinaire, finds a way to prove a murder featuring an unusual poison. Other shows you should check out! Old Timey Crimey: https://open.spotify.com/show/5RT0RA9i9kV7ldhWu04FcU?si=DiD_SV7ETwuo2ef77bV5Zg Short Story, Short Podcast: https://open.spotify.com/show/3q2moJE65wLBf0zFjqhMhu?si=3zbTwhkIQnOYVqbd_TmZYQ Social Media: Come chat with me on Twitter, FB, or Instagram! Sources: Nigel McCrery. Silent Witnesses: The Often Gruesome but Always Fascinating History of Forensic Science. David E. Newton. Forensic Chemistry. "Types of Poison." Britannica. "Jean Servais Stas." Wikipedia. D. Thorbun Burns, Henrik Deelstra. "Some aspects of the rise of analytical chemistry in Belgium." Analytical Bioanalytical Chemistry. Deborah Blum. "Nicotine and the Chemistry of Murder." Wired. Nene Adams. "Hippolyte Visart de Bocarme." Murderpedia. Music Deadly Roulette by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/3625-deadly-roulette License: http://creativecommons.org/licenses/by/4.0/ Dark Hallway (clean) by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/3607-dark-hallway-clean- Inspiring Chopin Nocturne by MusicLFiles Link: https://filmmusic.io/song/6937-inspiring-chopin-nocturne License: http://creativecommons.org/licenses/by/4.0/ Villainous Treachery by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/4588-villainous-treachery License: http://creativecommons.org/licenses/by/4.0/ Dark Dance by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/3604-dark-dance License: https://filmmusic.io/standard-license

If you thought a career in science means spending your best years in a dark laboratory for long, boring hours doing routine experiments, think again! Dr. Cora Young, from York University in Toronto, does a significant part of her environmental chemistry work in the field. From measuring air quality in residential and business spaces, to going high altitude on airplanes, or doing measurements in forests and even in the Arctic. In this episode, we discuss research in the growing field of environmental chemistry, how it differs from traditional analytical chemistry, and what it means bringing high precision analysis out of controlled laboratory environments. Dr. Young sheds light on how analyzing air quality can have a profound impact on international regulations and quality of life. From understanding emissions of worrisome pollutants such as polyfluoroalkyl substances (PFAS), to how cooking at home can affect our health, this is a fascinating discovery of the chemistry of air.

Episode 35: A conversation with Dr. Darren Williams of Sam Houston State University about cleaning processes and materials. Dr. Williams has been at SHSU since 2004 teaching Physical Chemistry, Forensic Chemistry, and graduate courses in Spectroscopy and Thermodynamics. He came to Huntsville from the US-DOE Pantex Plant in Amarillo. He taught at West Texas A&M University for four years after obtaining his Ph.D. from Oregon State University in 1997. He is originally from Fort Worth, and obtained his B.S. in chemistry from the University of Texas at Austin in 1992. He is the author of over two dozen research articles and book chapters covering a broad range of topics, such as cleaning process changes to reduce environmental impacts, contact angle methods for cleanliness verification, prediction of the spectroscopy of aged explosives, and chemical education improvements in Physical Chemistry. Dr. Williams leads the Cleaning Research Group at Sam Houston State University that studies all aspects of finishing and cleaning of high-value and mission-critical parts in the aerospace, medical, electronics, and manufacturing sectors. His lab has dry vapor spray, ultrasonic, vapor degreasing, and vacuum cycle cavitation cleaning equipment. The CRG formulates and tests azeotropic solvent blends, and measures flashpoint, viscosity, surface tension, and specific gravity. Much of the research is performed and published openly, but the CRG also performs contracted work under non-disclosure for external clients. Dr. Williams created the Product Quality Cleaning Workshop in 2018 to address the growing need for education on cleaning processes in industry. The next workshop is May 13-14th, 2020 at Sam Houston State University in Huntsville, TX. Registration is now open at https://tinyurl.com/wcnjjw5

On this episode we will focus on the factual side of mysteries. First we interview Rich Cohen and discuss his latest historical true crime. THE LAST PIRATE OF NEW YORK A GHOST SHIP, A KILLER AND THE BIRTH OF A GANGSTER NATION. The true account of Albert Hicks rise to become the man gangsters told stories about. He was the last man hung for piracy in New York.Next we interview Anita Zannin. She graduated Magna Cum Laude from Buffalo State College with a Bachelor of Science degree in Forensic Chemistry and a second Bachelor of Science degree in Criminal Justice. She received a Master of Science degree in Forensic Science from Syracuse University. Additionally, she taught for 4 years for Syracuse University's Forensic and National Security Sciences Institute and has been named a Visiting Professor at Francisco Marroquin Law School in Guatemala. Additionally she served as the faculty advisor to Syracuse University’s Forensic and National Security Sciences Institute’s Graduate Student Organization; Forensic Science: Code Orange (FSCO). Prior to entering the Forensics field, Ms. Zannin worked and studied in the medical field for many years. We discuss her role in crime solving and whether fiction gets it right.

In June 2019 Gudrun talked with Serena Carelli. Serena is member of the Research Training Group (RTG) Simet, which is based in Karlsruhe, Ulm and Offenburg. It started its work in 2017 and Gudrun is associated postdoc therein. The aim of that graduate school is to work on the better understanding of Lithium-ion batteries. For that it covers all scales, namley from micro (particles), meso (electrodes as pairs) to macro (cell) and involves scientists from chemistry, chemical engineering, material sciences, electro engineering, physics and mathematics. The group covers the experimental side as well as modeling and computer simulations. Serena is one of the PhD-students of the program. She is based in Offenburg in the group of Wolfgang Bessler (the deputy speaker of the RTG). Her research focusses on End-of-life prediction of a lithium-ion battery cell by studying the mechanistic ageing models of the graphite electrode among other things. Mathematical modelling and numerical simulation have become standard techniques in Li-ion battery research and development, with the purpose of studying the issues of batteries, including performance and ageing, and consequently increasing the model-based predictability of life expectancy. Serena and others work on an electrochemical model of a graphite-based lithium-ion cell that includes combined ageing mechanisms: Electrochemical formation of the solid electrolyte interphase (SEI) at the anode, breaking of the SEI due to mechanical stress from volume changes of the graphite particles, causing accelerated SEI growth, gas formation and dry-out of the electrodes, percolation theory for describing the loss of contact of graphite particles to the liquid electrolyte, formation of reversible and irreversible Li plating. The electrochemistry is coupled to a multi-scale heat and mass transport model based on a pseudo-3D approach. A time-upscaling methodology is developed that allows to simulate large time spans (thousands of operating hours). The combined modeling and simulation framework is able to predict calendaric and cyclic ageing up to the end of life of the battery cells. The results show a qualitative agreement with ageing behavior known from experimental literature. Serena has a Bachelor in Chemistry and a Master's in Forensic Chemistry from the University of Torino. She worked in Spain, the Politécnico de Torino and in Greece (there she was Marie Curie fellow at the Foundation for Research and Technology - Hellas) before she decided to spend time in Australia and India. References Serena's Linked in site A. Latz & J. Zausch: Thermodynamic consistent transport theory of Li-ion batteries, Journal of Power Sources 196 3296--3302, 2011. T. Seger: Elliptic-Parabolic Systems with Applications to Lithium-Ion Battery Models, Doktorarbeit Universität Konstanz, 2013. M. Kespe & H. Nirschl: Numerical simulation of lithium-ion battery performance considering electrode microstructure, International Journal of Energy Research 39 2062-2074, 2015. J.-M. Tarascon & M. Armand: Issues and challenges facing rechargeable lithium batteries, Nature 414 359-367, 2001. W.G. Bessler: Elektrische Energiespeicherung mit Batterien und Brennstoffzellen, Forschung im Fokus, Hochschule Offenburg (2018). Podcasts A. Jossen: Batterien, Gespräch mit Markus Völter im Omega Tau Podcast, Folge 222, 2016. J. Holthaus: Batterien für morgen und übermorgen, KIT.Audio Podcast, Folge 2, 2016. D. Breitenbach, U. Gebhardt, S. Gaedtke: Elektrochemie, Laser, Radio, Proton Podcast, Folge 15, 2016. M. Maier: Akkumulatoren, Gespräch mit G. Thäter im Modellansatz Podcast, Folge 123, Fakultät für Mathematik, Karlsruher Institut für Technologie (KIT), 2017. V. Auinger: Optimale Akkuladung, Gespräch mit G. Thäter im Modellansatz Podcast, Folge 160, Fakultät für Mathematik, Karlsruher Institut für Technologie (KIT), 2018.

In June 2019 Gudrun talked with Serena Carelli. Serena is member of the Research Training Group (RTG) Simet, which is based in Karlsruhe, Ulm and Offenburg. It started its work in 2017 and Gudrun is associated postdoc therein. The aim of that graduate school is to work on the better understanding of Lithium-ion batteries. For that it covers all scales, namley from micro (particles), meso (electrodes as pairs) to macro (cell) and involves scientists from chemistry, chemical engineering, material sciences, electro engineering, physics and mathematics. The group covers the experimental side as well as modeling and computer simulations. Serena is one of the PhD-students of the program. She is based in Offenburg in the group of Wolfgang Bessler (the deputy speaker of the RTG). Her research focusses on End-of-life prediction of a lithium-ion battery cell by studying the mechanistic ageing models of the graphite electrode among other things. Mathematical modelling and numerical simulation have become standard techniques in Li-ion battery research and development, with the purpose of studying the issues of batteries, including performance and ageing, and consequently increasing the model-based predictability of life expectancy. Serena and others work on an electrochemical model of a graphite-based lithium-ion cell that includes combined ageing mechanisms: Electrochemical formation of the solid electrolyte interphase (SEI) at the anode, breaking of the SEI due to mechanical stress from volume changes of the graphite particles, causing accelerated SEI growth, gas formation and dry-out of the electrodes, percolation theory for describing the loss of contact of graphite particles to the liquid electrolyte, formation of reversible and irreversible Li plating. The electrochemistry is coupled to a multi-scale heat and mass transport model based on a pseudo-3D approach. A time-upscaling methodology is developed that allows to simulate large time spans (thousands of operating hours). The combined modeling and simulation framework is able to predict calendaric and cyclic ageing up to the end of life of the battery cells. The results show a qualitative agreement with ageing behavior known from experimental literature. Serena has a Bachelor in Chemistry and a Master's in Forensic Chemistry from the University of Torino. She worked in Spain, the Politécnico de Torino and in Greece (there she was Marie Curie fellow at the Foundation for Research and Technology - Hellas) before she decided to spend time in Australia and India. References Serena's Linked in site A. Latz & J. Zausch: Thermodynamic consistent transport theory of Li-ion batteries, Journal of Power Sources 196 3296--3302, 2011. T. Seger: Elliptic-Parabolic Systems with Applications to Lithium-Ion Battery Models, Doktorarbeit Universität Konstanz, 2013. M. Kespe & H. Nirschl: Numerical simulation of lithium-ion battery performance considering electrode microstructure, International Journal of Energy Research 39 2062-2074, 2015. J.-M. Tarascon & M. Armand: Issues and challenges facing rechargeable lithium batteries, Nature 414 359-367, 2001. W.G. Bessler: Elektrische Energiespeicherung mit Batterien und Brennstoffzellen, Forschung im Fokus, Hochschule Offenburg (2018). Podcasts A. Jossen: Batterien, Gespräch mit Markus Völter im Omega Tau Podcast, Folge 222, 2016. J. Holthaus: Batterien für morgen und übermorgen, KIT.Audio Podcast, Folge 2, 2016. D. Breitenbach, U. Gebhardt, S. Gaedtke: Elektrochemie, Laser, Radio, Proton Podcast, Folge 15, 2016. M. Maier: Akkumulatoren, Gespräch mit G. Thäter im Modellansatz Podcast, Folge 123, Fakultät für Mathematik, Karlsruher Institut für Technologie (KIT), 2017. V. Auinger: Optimale Akkuladung, Gespräch mit G. Thäter im Modellansatz Podcast, Folge 160, Fakultät für Mathematik, Karlsruher Institut für Technologie (KIT), 2018.

Narcan and Synthetic Opioids: vive la résistance? Probably not. Read this absolutely brilliant piece from The Tox & The Hound here. (They did all the hard work and we stole their sources.) Opioid "resistance" to naloxone is most likely not a thing, per se. The reported effect from synthetic and novel opioids are unlikely to be due to the agent's binding affinity for receptors within the brain, but rather from an ability to rapidly permeate the blood brain barrier much faster than "traditional" opioids such as heroin. Even in cases where a synthetic opioid agent was identified, the vast majority of cases did not need more than 4mg of naloxone to achieve reversal. Synthetic opioids don't bind any more "tightly" to receptors than naloxone. Synthetic opioids will usually cross the blood brain barrier faster than traditionally encountered agents. Most available evidence shows that synthetic opioid toxicity does not require significantly more naloxone to achieve clinically significant effect. Ergo, the traditional serial naloxone dosing algorithm does not need much modification. 0.04mg -> 0.4mg -> 2mg -> 4mg -> 8mg -> 10mg Not all that "overdoses" is an opioid. Consider all other causes of altered mental status or coma. Namely: hypothermia, hypoxia, and hypercarbia. Acidosis may potentiate the effect of opioids, highlighting the demand for timely and effective ventilation. Polypharmacy or adulteration is increasingly common. Consider intoxication by additional agents. Anchoring bias is a dangerous phenomenon: don't get burned! The Nose Knows. Or does it? Intranasal (IN) naloxone is popular among many EMS agencies as well as law enforcement, fire departments, and bystanders. IN naloxone has been shown to be effective in several randomized controlled trials for successful reversal of opioid intoxication. However... There are important pitfalls to be cognizant of when choosing this option for delivering naloxone.  Intranasal naloxone has poor bioavailability when compared to IV or IM dosing, so higher doses may be required to achieve clinical effect. This is further potentiated by the maximum volume able to be absorbed by the nasal mucosa (around 0.5mL). Patients administered intranasal naloxone may have a variable or delayed response in achieving reversal. Protect Ya Neck Standard isolation precautions are adequate protection against the overwhelming majority of overdose scenes. In the rare instance where respiratory or splash exposure is a concern, a properly fitted N95 mask and goggles will be sufficient. To date, there has yet to be a laboratory confirmed case where a first responder or emergency healthcare provider has suffered a clinically significant opioid intoxication (bradypnea, hypoxia ) as the result of an occupational exposure to fentanyl or its analogues. TotalEM Podcast: https://www.totalem.org/emergency-professionals/podcast-73-ppe-in-opiate-overdoses References 1) Wax, P. M., Becker, C. E., & Curry, S. C. (2003). Unexpected “gas” casualties in Moscow: A medical toxicology perspective. Annals of Emergency Medicine, 41(5), 700–705. https://doi.org/10.1067/mem.2003.148 2) Stolbach, A. (2018). Is This Anything? Naloxone-resistant opioids. Retrieved from https://emcrit.org/toxhound/is-this-anything/ 3) Sutter, M. E., Gerona, R. R., Davis, M. T., Roche, B. M., Colby, D. K., Chenoweth, J. A., … Albertson, T. E. (2017). Fatal Fentanyl: One Pill Can Kill. Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine, 24(1), 106–113. https://doi.org/10.1111/acem.13034 4) Klar, S. A., Brodkin, E., Gibson, E., Padhi, S., Predy, C., Green, C., & Lee, V. (2016). Furanyl-Fentanyl Overdose Events Caused by Smoking Contaminated Crack Cocaine — British Columbia, Canada, July 15–18, 2016. MMWR. Morbidity and Mortality Weekly Report, 65(37), 1015–1016. https://doi.org/10.15585/mmwr.mm6537a6 5) Uddayasankar, U., Lee, C., Oleschuk, C., Eschun, G., & Ariano, R. E. (2018). The Pharmacokinetics and Pharmacodynamics of Carfentanil After Recreational Exposure: A Case Report. Pharmacotherapy. https://doi.org/10.1002/phar.2117 6) George, A. V., Lu, J. J., Pisano, M. V., Metz, J., & Erickson, T. B. (2010). Carfentanil--an ultra potent opioid. The American Journal of Emergency Medicine, 28(4), 530–2. https://doi.org/10.1016/j.ajem.2010.03.003 7) Melichar, J. K., Nutt, D. J., & Malizia, A. L. (2003). Naloxone displacement at opioid receptor sites measured in vivo in the human brain. Eur J Pharmacol, 459(2–3), 217–219. https://doi.org/10.1016/S0014-2999(02)02872-8 8) Cole, J. B., & Nelson, L. S. (2017). Controversies and carfentanil: We have much to learn about the present state of opioid poisoning. American Journal of Emergency Medicine. https://doi.org/10.1016/j.ajem.2017.08.045 9) Connors, N. J., & Nelson, L. S. (2016). The Evolution of Recommended Naloxone Dosing for Opioid Overdose by Medical Specialty. Journal of Medical Toxicology, 12(3), 276–281. https://doi.org/10.1007/s13181-016-0559-3 10) ACMT and AACT Position Statement: Preventing Occupational Fentanyl and Fentanyl Analog Exposure to Emergency Responders. (2016). https://doi.org/10.1007/s13181-017-0628-2 11) Casale, J. F., Mallette, J. R., & Guest, E. M. (2017). Analysis of illicit carfentanil: Emergence of the death dragon. Forensic Chemistry, 3, 74–80. https://doi.org/10.1016/j.forc.2017.02.003 12) Zuckerman, M., Weisberg, S. N., & Boyer, E. W. (2014). Pitfalls of intranasal naloxone. In Prehospital Emergency Care (Vol. 18, pp. 550–554). https://doi.org/10.3109/10903127.2014.896961 13) Chou, R., Korthuis, P. T., McCarty, D., Coffin, P. O., Griffin, J. C., Davis-O’Reilly, C., … Daya, M. (2017). Management of Suspected Opioid Overdose With Naloxone in Out-of-Hospital Settings. Annals of Internal Medicine, 167(12), 867. https://doi.org/10.7326/M17-2224 14) Rzasa Lynn, R., & Galinkin, J. (2018). Naloxone dosage for opioid reversal: current evidence and clinical implications. Therapeutic Advances in Drug Safety, 9(1), 63–88. https://doi.org/10.1177/2042098617744161 15) Kim, S., Wagner, H. N., Villemagne, V. L., Kao, P. F., Dannals, R. F., Ravert, H. T., … Civelek, a C. (1997). Longer occupancy of opioid receptors by nalmefene compared to naloxone as measured in vivo by a dual-detector system. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 38(11), 1726–31. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/9374341

Ryan Gregg, Ph.D. is a Medical Science Liaison at OneOme. He obtained a B.S. with Honors in Forensic Chemistry from the University of Mississippi, and a Ph.D. in Pharmacology from the Center for Substance Abuse and Research at Temple University School of Medicine. Ryan has a diverse background of experience in pre-clinical and clinical research in psychiatry, hematology, pain, and oncology. His role at OneOme centers around provider education and training on the utility and benefits of pharmacogenomic testing for the Northeast and Southeast United States, as well as working with physicians, pharmacists, and nurse practitioners to implement pharmacogenomic testing into clinical practice. OneOme's RightMed® pharmacogenomic test helps healthcare providers with timely, evidence-based prescription decisions by combining a patient's genetic profile and current medications in an interactive report that easily integrates into current practices. OneOme's RightMed test covers cardiovascular disease, cancer, chronic pain, diabetes, psychiatric conditions, and more. The OneOme platform was co-developed and exclusively licensed from Mayo Clinic to bring pharmacogenomics into routine clinical care.

Show Title: Research, Education, and the Future of Forensic Science: an Interview with Dr. Katherine A. Roberts, Director of the CSULA Graduate Program in Criminalistics  Dr. Roberts is the Director of the California State University, Los Angeles Graduate Program in Criminalistics. She has served as the Director of the Master of Science degree program there since 2002,and played a leading role in the university’s FEPAC accreditation. Her research interests cover a wide array of forensic disciplines, but focus primarily of trace evidence analysis, sexual assault evidence, and mitochondrial DNA analysis. Dr. Roberts was the PI of a National Institute of Justice-funded study to investigate the use of samplematrix™ to stabilize crime scene biological samples for optimized analysis and room temperature storage from 2009-2011. She is the PI for a National Science Foundation grant that was awarded to CSULA in 2015 to establish the Center for Interdisciplinary Forensic Science Research as a research site within the NSF Industry-University Cooperative Research Center (I/UCRC) program. The Center will enhance research training and education in multiple forensic science disciplines, including Forensic Microscopy, Trace Evidence Analysis, Forensic Science Research Methods, Forensic Chemistry, and Applications of Forensic Science. Dr. Roberts is currently collaborating with a consortium of European universities to develop a portable, inexpensive, and rapid method of dating latent fingerprints. Her publications are on topics related to trace evidence analysis, forensic examination of sexual assault evidence, and mitochondrial DNA analysis. Dr. Roberts is currently serving as the  Interim Executive Director of the California Forensic Science Institute.