Infection Control Matters

In this episode, Brett, Phil and Martin discuss a recent paper from the UK Health Security Agency (UKHSA) that examined the timeliness of data points that could be used for a centrally implemented, automated HCAI surveillance system in England, as a potential alternative to the 24 current locally-implemented system. The aim was to examine the potential for a national, automated surveillance system that could reduce the burden of the existing labour-intensive process for mandatory surveillance in England although the results were felt to be generalisable. Link to the paper we discuss: Quan TP, Eyre DW, Shadwell S, West D, Hopkins S, Chudasama D, et al. Timeliness of a potential automated system for national surveillance of healthcare-associated infections in England. J Hosp Infect 2025. https://doi.org/10.1016/j.jhin.2025.04.008. 

In this episode, we discuss the purpose of infection control matters and why we started the podcast. Recorded 1500 days after we started the podcast, Brett, Phil and Martin reflect on the podcast to date. For new listeners, is also a chance to learn more about our approach to the podcast and how to make the most of our website.

In this episode, we explore the crucial disconnect between national infection prevention and control (IPC) guidelines and the local policies implemented in residential aged care (RAC) facilities. Brett and Martin talk to Dr Sanne Peters and Dr Kirsty Buising about their recent paper that reports on their recent analysis using the AACTT (Action, Actor, Context, Target, Time) behavioural framework, which reveals a lack of alignment and specificity in many local IPC documents. We discuss: Why well-intentioned policies often fail to drive behaviour The implications of vague IPC statements in high-risk environments How local RAC settings can better translate national guidelines into actionable, behaviourally specific practices The role of co-design, leadership, and implementation science in bridging the gap The paper we discuss: Peters S, Lim LL, Francis JJ, Bennett N, Fetherstonhaugh D, Buising K, et al. Analysis of infection prevention and control documentation in residential aged care based on a behaviour specification framework. Infect Dis Health 2025. https://doi.org/10.1016/j.idh.2025.03.002.

In this episode Martin talks to Dr Andy Borman, (Acting Head and Consultant Clinical Scientist, UKHSA National UK Mycology Reference Lab. also Hon Professor of Medical Mycology, MRC CMM, University of Exeter), Dr Colin Brown (Deputy Director of Emerging and Epidemic Infections at UK Health Security Agency; Honorary Consultant in Infectious Diseases & Medical Microbiology at Royal Free London NHS Foundation Trust) and Dr Mariyam Mirfenderesky (Consultant in Medical Microbiology and Infectious Diseases North Middlesex and RF (AMS Lead) and UKHSA on HCAI). The UK Health Security Agency (UKHSA) is the national organisation in the United Kingdom responsible for protecting public health by preventing, detecting, and responding to infectious diseases and other health threats. We chat about how Candidozyma auris (formerly known as Candida auris) is identified in the lab, why it matters clinically, and what it means for infection prevention and control teams. From early lab detection to real-world frontline challenges, we discuss the key issues around this emerging pathogen — and what we need to do next. UK C. auris guidance can be found here: https://www.gov.uk/government/publications/candida-auris-laboratory-investigation-management-and-infection-prevention-and-control

In this episode of Infection Control Matters, we explore the potential of AI tools to support education and professional dialogue in infection prevention and control. We used NotebookLM, an experimental tool from Google designed to help users interact with their documents in new ways—summarising, clarifying, and even generating structured discussions based on uploaded content. Using research and guidance documents, we demonstrate how NotebookLM can be used to create a voice-generated conversation on key themes in IPC. The paper that we uploaded was the recently published cost-effectiveness research that relates to the CLEEN study that we have previously highlihghted. A link to the open access paper can be found below. The main part of this podcast was a dialogue created by NotebookLM following the upload of the paper. None of the voices are human (apart from Martin at the beginning and Brett at the end). This episode offers a glimpse into how AI might be used to support reflection, training, and knowledge sharing across the healthcare community... but with caveats!   The paper we discuss can be found here: Brain D, Sivapragasam N, Browne K, White NM, Russo PL, Cheng AC, et al. Economic Evaluation of Enhanced Cleaning and Disinfection of Shared Medical Equipment. JAMA Netw Open 2025;8(4):e258565. https://doi.org/10.1001/jamanetworkopen.2025.8565 NotebookLM: https://notebooklm.google/  

In this episode of Infection Control Matters, Martin Kiernan speaks with Dr. Nicole Stoesser about a large-scale, multi-centre study exploring the role of hospital sink infrastructure in antimicrobial resistance and pathogen dissemination. Representing the collaborative NITCAR-led "Sinkbug Consortium" we discuss surprising findings from 29 UK hospitals—including widespread antibiotic residues in sink traps—and reflect on the implications for sink design, waste disposal practices, and infection prevention strategies The paper we discuss is here: Rodger G, Chau K, Aranega Bou P, Moore G, Roohi A, The SinkBug Consortium, et al. Survey of healthcare-associated sink infrastructure, and sink trap antibiotic residues and biochemistry, in 29 UK hospitals. J Hosp Infect 2025. https://doi.org/10.1016/j.jhin.2025.02.002. Information on Nitcar: https://nitcollaborative.org.uk/wp/ Other papers of interest: Aranega-Bou P, George RP, Verlander NQ, Paton S, Bennett A, Moore G, et al. Carbapenem-resistant Enterobacteriaceae dispersal from sinks is linked to drain position and drainage rates in a laboratory model system. J Hosp Infect 2019;102(1):63-9. https://doi.org/10.1016/j.jhin.2018.12.007 Grabowski M, Lobo JM, Gunnell B, Enfield K, Carpenter R, Barnes L, et al. Characterizations of handwashing sink activities in a single hospital medical intensive care unit. J Hosp Infect 2018;100(3):e115-e22. https://doi.org/10.1016/j.jhin.2018.04.025

In this episode, Brett and Martin chat with Dr. Jessica Schults and Dr. Sally Havers about a recent study published in the American Journal of Infection Control. The study used a modified Delphi process to identify key healthcare infection surveillance priorities in Queensland. Through a two-round methodology, infection prevention experts identified 13 key infection measures for a standardized minimum dataset. This dataset aims to improve statewide HAI surveillance, enhance data consistency, and support targeted infection prevention efforts. The findings offer a model that could inform broader national and international surveillance strategies. The in-press paper is currently available here Schults JA, Havers S, Henderson B, Healy S, Runnegar N, Hurst T, et al. Expert consensus and recommendations for Healthcare-Associated Infection surveillance in Queensland, Australia: A modified Delphi study. Am J Infect Control 2025. https://doi.org/10.1016/j.ajic.2025.02.012.

In this episode, Phil and Martin talk to Dr Aline Wolfensberger, Senior Attending Physician, Department of Infectious Diseases and Hospital Epidemiology at University Hospital Zurich and a Senior Researcher at the Institute for Implementation Science in Health Care at the Univetsity of Zurich. We discuss a recent paper that has analysed a range of algorithms for detecting non-ventilator associated pneumonia (nvHAP) that have the potential for significantly reducing the surveillance burden. This work also demonstrated the value of an annual local hospital-wide point prevalence survey that provides data on which areas to target. Relevant reading: [1] Mueller A, Pfister M, Faes Hesse M, Zingg W, Wolfensberger A, Swissnoso G. Development and validation of selection algorithms for a non-ventilator hospital-acquired pneumonia semi-automated surveillance system. Clin Microbiol Infect 2024. https://doi.org/10.1016/j.cmi.2024.11.032 [2] Wolfensberger A, Scherrer AU, Sax H. Automated surveillance of non-ventilator-associated hospital-acquired pneumonia (nvHAP): a systematic literature review. Antimicrob Resist Infect Control 2024;13(1):30. https://doi.org/10.1186/s13756-024-01375-8 [3] Wolfensberger A, Jakob W, Faes Hesse M, Kuster SP, Meier AH, Schreiber PW, et al. Development and validation of a semi-automated surveillance system-lowering the fruit for non-ventilator-associated hospital-acquired pneumonia (nvHAP) prevention. Clin Microbiol Infect 2019;25(11):1428 e7- e13. https://doi.org/10.1016/j.cmi.2019.03.019

In this episode Martin Talks to Silvana Gastaldi who is a infection prevention and control health referent at UK-MED (a frontline humanitarian medical NGO). We discuss her revent paper in the Journal of Hospital Infection that reviews the literature on methods of assessing how effective environmental cleaning services and procedures are, including ATP, fluorescent UV marking, visual and microbiological methods and also discuss the potential for AI to assist in the healthcare environmental decontamination arena. The paper we discuss: Gastaldi S, Accorgi D, D'Ancona F. Tools and strategies for monitoring hospital environmental hygiene services. J Hosp Infect 2025. https://doi.org/10.1016/j.jhin.2025.01.011 To listen to a previous podcast in which Dr Phil Carling, developer of the UV marking systems talks about it's development and initial use please click here Podcast website and collections: www.infectioncontrolmatters.com

In this episode, Phil Russo talks to Brett Mitchell and Kate Browne about a study that did not make it over the line. Following a systematic review in 2021 that examined the issue of UTIs in those who self catheterise, a study to examine whether previous work demonstrating a reduction in CAUTI in indwelling catheters through the use of Chlorhexidine for meatal cleansing would be effective was designed. The team discuss the complexities of getting what was essentially a community-based study over the line and why ultimately it did not progress, much to the sadness of the team. previous relevant work is listed below. Mitchell BG, Prael G, Curryer C, Russo PL, Fasugba O, Lowthian J, et al. The frequency of urinary tract infections and the value of antiseptics in community-dwelling people who undertake intermittent urinary catheterization: A systematic review. Am J Infect Control 2021;49(8):1058-65. https://doi.org/10.1016/j.ajic.2021.01.009. Fasugba O, Cheng AC, Gregory V, Graves N, Koerner J, Collignon P, et al. Chlorhexidine for meatal cleaning in reducing catheter-associated urinary tract infections: a multicentre stepped-wedge randomised controlled trial. Lancet Infect Dis 2019;19(6):611-9. https://doi.org/10.1016/S1473-3099(18)30736-9.  

In this episode Brett and Phil chat about a few of the posters presented at the Australasian College for Infection Prevention and Control 2024 Conference held in Melbourne in November 2024. Poster topics include hand hygiene, surveillance, and a pilot RCT on chlorhexidine impregnated dressings.   You can access poster abstracts below and a pdf of the posters here Improving Hand Hygiene Practices in the Marshall Islands Epidemiology of Hospital-acquired Bloodstream Infections at a Quaternary Hospital Service An antimicrobial dressing for prevention of infection complication related peripheral intravenous catheter: an international randomised controlled trial. Comparing Healthcare Associated Infection data to Hospital Acquired Complication Infection data collection and finding the documentation differences to improve accuracy  

In this episode recorded at the 2024 Australasian College of Infection Prevention and Control (ACIPC) Conference in Melbourne, Brett and Phil talk to Dr Sarah Browning (ID Physician at Hunter New England) and two Junior Medical Officers (JMOs) Sam and Lochlan who worked on IPC-related projects whilst on placement.

In this episode, Brett, Phil and Martin reflect on the year. We chat about favourite podcasts, papers and conferences in our usual informal manner (well probably even more informal than normal). Papers we mention are listed below. Cimen C, Bathoorn E, Loeve AJ, Fliss M, Berends MS, Nagengast WB, et al. Uncovering the spread of drug-resistant bacteria through next-generation sequencing based surveillance: transmission of extended-spectrum beta-lactamase-producing Enterobacterales by a contaminated duodenoscope. Antimicrob Resist Infect Control 2024;13(1):31. https://doi.org/10.1186/s13756-024-01386-5 Torres-Teran MM, Greentree DH, Varghese MM, Cadnum JL, Pavis RL, Saade EA, et al. Identifying and Remediating Super-splasher Sinks to Reduce Dispersal of Pathogens From Sink Drains. Open Forum Infect Dis 2024;11(7):ofae293. https://doi.org/10.1093/ofid/ofae293 Bush M, Bennett CM, Hutchinson A, Bouchoucha SL. Post implementation quarantine recommendations that support preparedness: A systematic review and quarantine implementation capability framework. Infect Dis Health 2024;29(3):152-71. https://doi.org/10.1016/j.idh.2024.02.004 Dhar S, Jinadatha C, Kilgore PE, Henig O, Divine GW, Todter EN, et al. Lowering the Acquisition of Multidrug-Resistant Organisms (MDROs) With Pulsed-xenon (LAMP) Study: A Cluster-Randomized, Controlled, Double-Blinded, Interventional Crossover Trial. Clin Infect Dis 2024;79(4):1024-30. https://doi.org/10.1093/cid/ciae240 Widmer AF, Atkinson A, Kuster SP, Wolfensberger A, Klimke S, Sommerstein R, et al. Povidone Iodine vs Chlorhexidine Gluconate in Alcohol for Preoperative Skin Antisepsis: A Randomized Clinical Trial. JAMA 2024;332(7):541-9. https://doi.org/10.1001/jama.2024.8531 Leistner R, Kohlmorgen B, Brodzinski A, Schwab F, Lemke E, Zakonsky G, et al. Environmental cleaning to prevent hospital-acquired infections on non-intensive care units: a pragmatic, single-centre, cluster randomized controlled, crossover trial comparing soap-based, disinfection and probiotic cleaning. EClinicalMedicine 2023;59:101958. https://doi.org/10.1016/j.eclinm.2023.101958 Denkel LA, Voss A, Caselli E, Dancer SJ, Leistner R, Gastmeier P, et al. Can probiotics trigger a paradigm shift for cleaning healthcare environments? A narrative review. Antimicrob Resist Infect Control 2024;13(1):119. https://doi.org/10.1186/s13756-024-01474-6  

In this episode of ICMs we talk to the authors of a world first multi-centre double blind cross-over randomised control trial, which explored the effect of in-room air purification on acute respiratory tract infections.  The rationale and pragmatics of undertaking such a trial are explored, as well as interpretation of the findings.   The lead researcher, Bismi Thottiyil Sultanmuhammed Abdul, a PhD student at the University of Newcastle is joined by some of her supervisors Professors Jenny Sim and Brett Mitchell to explain this study.   The paper can be accessed here: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2825943?resultClick=1   Reference: Khadar, B. T. S. A., Sim, J., McDonald, V. M., McDonagh, J., Clapham, M., & Mitchell, B. G. (2024). Air Purifiers and Acute Respiratory Infections in Residential Aged Care: A Randomized Clinical Trial. JAMA Network Open, 7(11), e2443769-e2443769.      

In this episode, Martin talks to Dr Rebecca Crapanzano-Sigafoos (formerly Bartles) who is Executive Director, Center for Research, Practoce and Innovation at the Association for Professionals in Infection Control and Epidemiology (APIC). We talk about about her work on staffing levels for IPC Teams, beginning with her early work looking at workload and then the recent review and paper on data obtained from the beta version of the APIC Staffing Calculator. It turns out that the vast majority of 390+ participating organisations are understaffed.. What might help however was the finding that hospitals that were better staffed had significantly lower infection rates according to accepted published data. Papers we discuss are found below: Bartles R, Dickson A, Babade O. A systematic approach to quantifying infection prevention staffing and coverage needs. Am J Infect Control 2018;46(5):487-91. https://doi.org/10.1016/j.ajic.2017.11.006. Knighton SC, Engle J, Berkson J, Bartles R. A narrative review of how infection preventionist (IP) staffing and outcome metrics are assessed by health care organizations and factors to consider. Am J Infect Control 2024;52(1):91-106. https://doi.org/10.1016/j.ajic.2023.06.017. Bartles R, Reese S, Gumbar A. Closing the gap on infection prevention staffing recommendations: Results from the beta version of the APIC staffing calculator. Am J Infect Control 2024. https://doi.org/10.1016/j.ajic.2024.09.004.

In this episode, Martin talks to Cansu Cimen, a researcher at University Hospitals Groningen in the Netherlands, about a recent paper that documents an outbreak and in particular the critical role of next-generation sequencing (NGS) in tracking and controlling the transmission of MDROs via contaminated duodenoscopes. Focusing on an outbreak linked to ESBL-producing Citrobacter freundii and Klebsiella pneumoniae after endoscopic retrograde cholangiopancreatography (ERCP), standard culture methods failed to detect contamination. After many negative cultures using established methods, destructive dismantling of the implicated scope revealed contamination on hard-to-clean components, highlighting NGS as an effective tool for identifying pathogen transmission pathways. Cimen C, Bathoorn E, Loeve AJ, Fliss M, Berends MS, Nagengast WB, et al. Uncovering the spread of drug-resistant bacteria through next-generation sequencing based surveillance: transmission of extended-spectrum beta-lactamase-producing Enterobacterales by a contaminated duodenoscope. Antimicrob Resist Infect Control 2024;13(1):31. https://doi.org/10.1186/s13756-024-01386-5. Download the paper here

In this episode recorded live at the IPS Conference in Birmingham UK in September 2024, Martin talks to Claire Fitzsimons, Senior Infection Prevention and Control Practitioner at the Northern Ireland Ambulance Service Health and Social Care Trust. We discuss a poster that she presented at the conference that looked as ways of reducing glove use in the ambulance service through a range of improvement methodologies. A copy of the poster can be found here

In this episode, recorded at the 2024 Infection Prevention Society Conference in Birmingham (UK) Brett and Martin talk to Conor McGinn, Assistant Professor in the Department of Mechanical and Manufacturing Engineering at Trinity College Dublin and CEO of Akara AI, a robotics company spin-off from Trinity. We talk about a presentation that Conor gave, demonstrating how infrared sensors analysed by AI can provode feedback on techniques in the operating room and how they could improve cleaning standards in hospitals. A link to the video we discussed is here https://youtu.be/CPCFuXyQarY?si=xh1RjXAaKeKY708a and you can also see Conor's talk here https://youtu.be/3SCEkbwKhM4?si=uztJcnVIAe-vq5U8

In our second live session at a major conference, this episode of Infection Control Matters was recorded live at a plenary session to close day 1 of the Infection Prevention Society conference (Birmingham, UK). Our guest panelists include Dr Berit Muller-Pebody an Epidemiologist from the UK Health Security Agency, Prof Jennie Wilson from the University of West London and Dr Jacqui Prieto from The University of Southampton. The panel also fielded many questions from delegates from the floor. Topics covered include the role of mandatory surveillance, de-implementation, community based IPC, point prevalence studies, the UK PPS,  fundamentals of care, urinary tract infection, pneumonia and the direction of IPC.      

Dr Gemma L Saravanos (she/her) is an infectious diseases epidemiologist and a Registered Nurse leading public health research, and education of pre-registration nursing students. She is based at the Susan Wakil School of Nursing and Midwifery, University of Sydney and works across the Camperdown (Patyegarang) and Westmead (Baludarri) campuses in Sydney.   In this episode, Phil chats to Gemma about an open access publication she led discussing IPC programs contribution to environmental harm, and argues the case that increased investment in IPC is crucial for sustainable health and environmental systems.   Saravanos, G.L., Islam, M.S., Huang, Y. et al. Infection prevention and control programme priorities for sustainable health and environmental systems. BMC Global Public Health 2, 6 (2024). https://doi.org/10.1186/s44263-023-00031-4 

Our guest host, Dr Sally Havers this week talks to some of authors from ClEaning and Enhancd DisinfectioN (CLEEN) study (including some regular voices..). The study was recently published in the Lancet Infectious Disease (link below).   The CLEEN study is a world first RCT that explores the impact of cleaning and disinfection of shared medical equipment on HAIs. The study reports significant reductions in HAIs associated with increased cleaning and disinfection of shared equipment.   In this chat, the background to the study is discussed, as well as some implementation and practical considerations. We also touch on the time it takes to clean, which is related to another paper from the CLEEN study recently published in the Journal of Hospital Infection.   For those attending the 2024 IPS conference in Birmingham in a few weeks, Brett will be presenting the full methodology and main effectiveness results at the conference. Early cost-effectiveness data will also be presented, as well as results from a time and motion study exploring how long it takes to clean equipment. For those attending the 2024 ACIPC conference in Melbourne in November, there is a concurrent session on the main effectiveness results and a lightning session on how long it takes to clean equipment.   Publications Browne, K., White, N. M., Russo, P. L., Cheng, A. C., Stewardson, A. J., Matterson, G., ... & Mitchell, B. G. (2024). Investigating the effect of enhanced cleaning and disinfection of shared medical equipment on health-care-associated infections in Australia (CLEEN): a stepped-wedge, cluster randomised, controlled trial. The Lancet Infectious Diseases.   Matterson, G., Browne, K., Tehan, P., Russo, P. L., Kiernan, M., & Mitchell, B. G. (2024). Cleaning time and motion: an observational study on the time required to effectively clean shared medical equipment in hospitals. Journal of Hospital Infection.  

In this episode, Brett and Martin discuss a recent paper from Sarah Browning and colleagues that describes how an RCT on the ending of aspects of contact precautions (gloves and aprons) for MRSA and VRE could be conducted. The paper can be found here: https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(24)00243-X/abstract   Our other podcasts on contact precautions, gloves and aprons can be found here: https://infectioncontrolmatters.podbean.com/e/have-gloves-had-their-day/ https://infectioncontrolmatters.podbean.com/e/reflecting-on-a-contact-precautions-talk-at-eccmid-with-dr-gonzalo-bearman/ https://infectioncontrolmatters.podbean.com/e/25-years-of-contact-precautions-but-benefit-or-harm-and-what-is-the-evidence-with-prof-jennie-wilson/    

In this episode, Martin Kiernan catches up with Dr Gonzalo Bearman, Professor of Internal Medicine at Virginia Commonwealth University, Richmond, USA. We talk about the opportunities and dangers of using large language models like ChatGPT in the infecton prevention space. A link to a recent open access paper on this topic is here Langford BJ, Branch-Elliman W, Nori P, Marra AR, Bearman G. Confronting the Disruption of the Infectious Diseases Workforce by Artificial Intelligence: What This Means for Us and What We Can Do About It. Open Forum Infect Dis. 2024;11:ofae053 https://www.ncbi.nlm.nih.gov/pubmed/38434616 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906702/pdf/ofae053.pdf 

In this episode, Martin Kiernan talks to representatives of the Multi-disciplinary Team at Leeds Teaching Hospitals NHS Trust in the UK, Dr Jessica Martin IPC Matron Adele Dyche and Haematology Matron Katie Sweeting . Building on from previously published work, they describe how efforts from the front line can impact on water safety, including initiatives such as sink removal, education programmes and collaborative working. This work won the 2023 award for Infection Prevention and Control at the annual Nursing Times Awards The original paper from the group can be found here: Rice W, Martin J, Hodgkin M, Carter J, Barrasa A, Sweeting K, et al. A protracted outbreak of difficult-to-treat resistant Pseudomonas aeruginosa in a haematology unit: a matched case-control study demonstrating increased risk with use of fluoroquinolone. J Hosp Infect. 2023;132:52-61. https://www.ncbi.nlm.nih.gov/pubmed/36563938

In this episode, Brett and Martin report on a visit to the massive Interclean Expo held biannually in Amsterdam and the Healthcare Hygiene meeting. We report on the staggering range of equipment available and the fact that IPC often has little say in this especially if there are potential risks, referring to a previous podcast https://infectioncontrolmatters.podbean.com/e/investigating-a-unique-cpeoutbreak-a-possible-new-place-to-look/   Click here for a video of one hall at Interclean (of 12).  

In this episode, Martin has been on the road again and talks to two poster presenters at the IPAC-Canada 2024 conference. In the first part, Martin talks to Margaret Cameron from Peterborough Regional Health Centre, Ontario about the use of the Multiple Mini Interviewing approach to the selection of suitable candidates to become part of the hospital Environmental Service Attendant team. This innovative approach uses scenarios to test a candidate's suitability for this important role. In the second part, Karrie Yausie from Saskatchewan health Authority talks about a blip in orthopaedic implant SSI rates that was investigated with some interesting aspects.   You can download Margaret's poster here and Karrie's here

This week we have a second batch of posters that we liked at ESCMID Global and will be talking about: VRE Surveillance using hospital waste water during an outbreak Assessing the Hawthorne effect: Implications and solutions The impact of an early Infectious Disease consultation for CLABSI: a single centre retrospective study Semi-continuous disinfection of sinks with UVC on a haematologydepartment for infection prevention Urinary tract microbiome of asymptomatic individuals with spinal cord injury Nurses known to be colonized with livestock-associated MRSA did not cause transmission to patients Clostridium difficile contamination of australian retail vegetables and households Prolonged use of breathing systems used in anesthesia for up to 7 days instead of 24H A pdf of the posters can be downloaded here

In this episode Brett, Phil and Martin tour the posters at ESCMID Global 2024 and we discuss some of them with the authors. A link to images of the posters can be found below. Here are the posters we discuss AMR Surveillance in waste water and clinical isolates from a tertiary hospital: Preliminary results Deciphering the temporal short-term dynamics of Acinetobacter baumanii: Impact of colonisation pressure in infection in an endemic Indian intensive care unit (Manasa Tantry discussion) Post-antibiotic risk for recurrent lower respiratory tract infection during prolonged hospitalisation Transmission of MDRO during physical and occupational therapy appointmants a 3 Veterans Affairs Hospitals Aircraft lavatory wastewater surveillance for SARS-CoV2 and other coronaviruses by using family-wide RT-PCR, Thailand, October – November 2023 Enhancing feedback and implementation of infection risk scan findings (IRIS) among healthcare workers in nursing homes Proper glove use: a multicentre before-after regional study (Anne F. Voor and Juliëtte Severin discussion) Poster link to see the posters we discuss Posters from ESCMID Global - Part 1 More posters to come!

It was day 3 at ESCMID Global 2024 and Phil, Brett and Martin mull over the day. Amongst the items we discuss are: What does endogenous really mean? AI in the IPC space - friend or foe? Fungal outbreaks - epidemiological challenges and tracing the source Automated bloodstream infection surveillance The Euro PPS survey results - data in action (or inaction) Subsequent to the podcast recording the ECDC PPS results have been published and can be found here: https://www.ecdc.europa.eu/sites/default/files/documents/healthcare-associated--infections-antimicrobial-use-point-prevalence-survey-2016-2017.pdf

In this episode, Phil, Brett and Martin dicuss more sessions from ESCMID Global (Barcelona, 2024). We talk about sessions on cleaning the occupied bed space, SSI prevention and the difficulty of designing and executing good studies in IPC. We were particularly interested in papers from Italy on the use of probiotics in IPC and some papers from Prof Cassini's group are highlighted below. Calabro GE, Caselli E, Rognoni C, Laurenti P, Moscato U, ML DIP, et al. [Health Technology Assessment of the introduction of the Probiotic Cleaning Hygiene System (PCHS) in the Italian healthcare setting: update]. J Prev Med Hyg. 2023;64:E1-E35. https://www.ncbi.nlm.nih.gov/pubmed/37881619 D'Accolti M, Soffritti I, Bini F, Mazziga E, Cason C, Comar M, et al. Shaping the subway microbiome through probiotic-based sanitation during the COVID-19 emergency: a pre-post case-control study. Microbiome. 2023;11:64. https://www.ncbi.nlm.nih.gov/pubmed/36991513 D'Accolti M, Soffritti I, Bini F, Mazziga E, Mazzacane S, Caselli E. Pathogen Control in the Built Environment: A Probiotic-Based System as a Remedy for the Spread of Antibiotic Resistance. Microorganisms. 2022;10. https://www.ncbi.nlm.nih.gov/pubmed/35208679 Caselli E, Purificato I. Could we fight healthcare-associated infections and antimicrobial resistance with probiotic-based sanitation? Commentary. Ann Ist Super Sanita. 2020;56:263-6. https://www.ncbi.nlm.nih.gov/pubmed/32959791| Caselli E, D'Accolti M, Vandini A, Lanzoni L, Camerada MT, Coccagna M, et al. Impact of a Probiotic-Based Cleaning Intervention on the Microbiota Ecosystem of the Hospital Surfaces: Focus on the Resistome Remodulation. PLoS One. 2016;11:e0148857. https://www.ncbi.nlm.nih.gov/pubmed/26886448

In this episode, Brett, Martin and Phil mull over the newly published WHO discussion document on respiratory particles and Martin catches up with Prof Cath Noakes from the School of Engineering in Leeds, UK to get her take on it.   You can download the document we are discussing here https://www.who.int/publications/m/item/global-technical-consultation-report-on-proposed-terminology-for-pathogens-that-transmit-through-the-air

In this podcast, Brett and Martin reflect on the "Infection Control Papers of the Year" presented at ECCMID (AKA ESCMID Global) 2024. Here are a selection of some of the papers mentioned: Decolonization in Nursing Homes to Prevent Infection and Hospitalization https://pubmed.ncbi.nlm.nih.gov/37815935/ Reducing Hospitalizations and Multidrug-Resistant Organisms vi a Regional Decolonization in Hospitals and Nursing Homes https://pubmed.ncbi.nlm.nih.gov/38557703/ Prevention of non-ventilator-associated hospital-acquired pneumonia in Switzerland: a type 2 hybrid effectiveness-implementation trial https://pubmed.ncbi.nlm.nih.gov/36893785/ Skin Antisepsis before Surgical Fixation of Extremity Fractures https://www.nejm.org/doi/full/10.1056/NEJMoa2307679 Trial of Vancomycin and Cefazolin as Surgical Prophylaxis in Arthroplasty https://www.nejm.org/doi/full/10.1056/NEJMoa2301401 Investigation of individual nurses' relative hand hygiene performance using an anonymous automated electronic hand hygiene monitoring system and a nursing assignment schedule https://www.ajicjournal.org/article/S0196-6553(22)00468-0/abstract Environmental cleaning to prevent hospital-acquired infections on non-intensive care units: a pragmatic, single-centre, cluster randomized controlled, crossover trial comparing soap-based, disinfection and probiotic cleaning https://pubmed.ncbi.nlm.nih.gov/37089619/

In our first episode from ECCMID Global 2024, Martin and Brett reflect on the session on design of the healthcare environment sessions from Profs Hilary Humphries and Cath Noakes and a flash poster session featuring VRE Reservoirs in the environment and a tremendous piece of  Burkolderia sleuthing from the UKHSA

In this podcast, we chat with Dr Brian Forde about HAIviz. HAIviz an interactive dashboard for visualising and integrating healthcare-associated genomic epidemiological data. HAIviz displays and links the outbreak timeline, building map, phylogenetic tree, patient bed movements, and transmission network on a single interactive dashboard. You can view and use the tool for free at Permana, B., Harris, P. N., Roberts, L. W., Cuddihy, T., Paterson, D. L., Beatson, S. A., & Forde, B. M. (2024). HAIviz: an interactive dashboard for visualising and integrating healthcare-associated genomic epidemiological data. Microbial Genomics, 10(2), 001200.    

In this episode, Martin Kiernan talks to Mitch Clarke, Clinical Lead and Deputy Director of Infection Prevention and Control at Nottingham University Hospitals in the UK. We discuss an outbreak with a unique NDM CPE infection and look at where the investigations went, including a new reservoir that is a potential source - the floor scrubber. Papers underpinning this work are here: 1. Benbow A, Clarke M, Yates C, Montgomery R, Staniforth K, Boswell T, et al. Hospital-wide healthcare-associated carbapenemase-producing Enterobacterales outbreak: risks of electric floor scrubbers in catering facilities and kitchens. J Hosp Infect. 2024;146:59-65. https://www.ncbi.nlm.nih.gov/pubmed/38341149 2. Prescott K, Billam H, Yates C, Clarke M, Montgomery R, Staniforth K, et al. Outbreak of New Delhi Metallo-Beta-lactamase Carbapenemase Producing Enterobacterales on a bone marrow transplant unit: Role of the environment. Infect Prev Pract. 2021;3:100125. https://www.ncbi.nlm.nih.gov/pubmed/34368742

In this episode, Martin Talks to Dr Mark Wilcox OBE, Professor of Microbiology at the University of Leeds, Head of Microbiology Research & Development at Leeds University Hospitals NHS Trust and National Clinical Director for Infection Prevention and Control at NHS England. We mull over the possible reasons for the increase in hospital-onset, hospital attributed cases in England, including ribotypes and antibiotic use. Given that the NHS is under great stress, we discuss the damage potential from a ribotype 955 which shares some genetic characteristics with the 027 ribotype that caused so many problems in the UK and worldwide in the early 2000s. One thing that we agree on is that reductions targets (with teeth) have been very successful in the past and should we venture in that direction again? Information on data collection, hospital and national typing reports for England can be found here: https://www.gov.uk/government/collections/clostridium-difficile-guidance-data-and-analysis#epidemiology

In this episode, after an interesting discovery when searching Youtube, Brett and Martin mull over whether toilet plume is a risk factor for hospital-acquired pneumonia and C. difficile infections. The papers we discuss are listed below. Goforth MP, Boone SA, Clark J, Valenzuela PB, McKinney J, Ijaz MK, et al. Impacts of lid closure during toilet flushing and of toilet bowl cleaning on viral contamination of surfaces in United States restrooms. Am J Infect Control 2023. https://doi.org/10.1016/j.ajic.2023.11.020 Best EL, Sandoe JA, Wilcox MH. Potential for aerosolization of Clostridium difficile after flushing toilets: the role of toilet lids in reducing environmental contamination risk. J Hosp Infect 2012;80(1):1-5. https://doi.org/10.1016/j.jhin.2011.08.010 Lai ACK, Tan TF, Li WS, Ip DKM. Emission strength of airborne pathogens during toilet flushing. Indoor Air 2018;28(1):73-9. https://doi.org/10.1111/ina.12406

We chat with Dr Deirdre Fitzgerald-Hughes and Aoife Kearney about a national survey undertaken in Ireland. In the survey, they explored CPE knowledge and practices of healthcare workers, including infection prevention and control staff. There were some interesting findings that may be useful in informing IPC education and training, including convincing people that they need to know more. The paper we discuss is: Kearney, A., Humphreys, H., & Fitzgerald-Hughes, D. (2023). Infection prevention and control policy implementation for CPE: A cross-sectional national survey of healthcare workers reveals knowledge gaps and sub-optimal practices. Journal of Hospital Infection. https://doi.org/10.1016/j.jhin.2023.12.007  

In this episode, Martin Kiernan and Phil Russo talk to Professor Michael Borg of the Faculty of Medicine & Surgery in the Medical School at the University of Malta and Head of Department (Infection Control) at Mater Dei Hospital in Malta. We discuss a recent paper desctibing the stages that brought about a 90% reduction in MRSA bloodstream infections over a ten-year period. The main paper we discuss: Borg MA, Suda D, Tartari E, Farrugia C, Xuereb D, Borg Inguanez M. Preventing healthcare-associated MRSA bacteremia: getting to the root of the problem. Antimicrob Steward Healthc Epidemiol 2023;3(1):e248. https://doi.org/10.1017/ash.2023.518 Other papers by Michael include: Borg MA, Suda D, Scicluna E, Brincat A, Zarb P. Universal admission screening: a potential game-changer in hospitals with high prevalence of MRSA. J Hosp Infect 2021;113:77-84. https://doi.org/10.1016/j.jhin.2021.03.024 Borg MA, Brincat A. Addressing the controversy of 100% hand hygiene compliance: can alcohol rub consumption data serve as a useful proxy validator? J Hosp Infect 2018;100(2):218-9. https://doi.org/10.1016/j.jhin.2018.04.024 Borg MA, Waisfisz B, Frank U. Quantitative assessment of organizational culture within hospitals and its relevance to infection prevention and control strategies. J Hosp Infect 2015;90(1):75-7. https://doi.org/10.1016/j.jhin.2014.12.015 Borg MA. Lowbury Lecture 2013. Cultural determinants of infection control behaviour: understanding drivers and implementing effective change. J Hosp Infect 2014;86(3):161-8. https://doi.org/10.1016/j.jhin.2013.12.006 De Bono S, Heling G, Borg MA. Organizational culture and its implications for infection prevention and control in healthcare institutions. J Hosp Infect 2014;86(1):1-6. https://doi.org/10.1016/j.jhin.2013.10.007 Borg MA, Hulscher M, Scicluna EA, Richards J, Azanowsky JM, Xuereb D, et al. Prevention of meticillin-resistant Staphylococcus aureus bloodstream infections in European hospitals: moving beyond policies. J Hosp Infect 2014;87(4):203-11. https://doi.org/10.1016/j.jhin.2014.05.00

In this week's episode, Martin talks to Dr Tina Joshi, Associate Professor of Molecular Microbiology in Peninsula Dental School at the University of Plymouth, UK. We discuss her longstanding interest in Clostridioides difficile and her many publications, one of which on the effectiveness of hypochlorite (or lack of it) on spores has been widely covered in the media. We chat about spore attachment to surfaces, the effect of disinfectants and the differences between strains. Some of Tina's papers are listed here. Joshi LT, Phillips DS, Williams CF, Alyousef A, Baillie L. Contribution of spores to the ability of Clostridium difficile to adhere to surfaces. Appl Environ Microbiol 2012;78(21):7671-9. https://doi.org/10.1128/AEM.01862-12 Joshi LT, Welsch A, Hawkins J, Baillie L. The effect of hospital biocide sodium dichloroisocyanurate on the viability and properties of Clostridium difficile spores. Lett Appl Microbiol 2017;65(3):199-205. https://doi.org/10.1111/lam.12768 Dyer C, Hutt LP, Burky R, Joshi LT. Biocide Resistance and Transmission of Clostridium difficile Spores Spiked onto Clinical Surfaces from an American Health Care Facility. Appl Environ Microbiol 2019;85(17). https://doi.org/10.1128/AEM.01090-19 Waterfield S, Ahmed H, Jones IA, Burky R, Joshi LT. Isolation of Clostridioides difficile PCR Ribotype 027 from single-use hospital gown ties. J Med Microbiol 2022;71(6). https://doi.org/10.1099/jmm.0.001550 Ahmed H, Joshi LT. Clostridioides difficile spores tolerate disinfection with sodium hypochlorite disinfectant and remain viable within surgical scrubs and gown fabrics. Microbiology (Reading) 2023;169(11). https://doi.org/10.1099/mic.0.001418 Malyshev D, Jones IA, McKracken M, Oberg R, Harper GM, Joshi LT, et al. Hypervirulent R20291 Clostridioides difficile spores show disinfection resilience to sodium hypochlorite despite structural changes. BMC Microbiol 2023;23(1):59. https://doi.org/10.1186/s12866-023-02787-z.

In our usual Christmas episode, Brett, Phil and Martin choose our papers and podcasts of 2023. Also this time, Martin set the three of us a challenge: to find an interesting IPC-related paper from the years of our birth (more challenging for some than others..). Martin also reveals the No 1 single in our respective countries on the day of our birth. For Martin, a near miss. For Phil, a very apt song and for Brett... well, his karaoke debut cannot be far off.. Happy holidays everyone!   Martin's 1955 paper: Lowbury, E. J. (1955). "Cross-infection of wounds with antibiotic-resistant organisms." Br Med J 1(4920): 985-990. https://doi.org/10.1136/bmj.1.4920.985 Phil's 1964 paper: Murray, D. G. (1964). "Wound Infections after Surgery for Fractured Hip. A Follow-up Study." JAMA 190: 505-508. https://doi.org/10.1001/jama.1964.03070190025005 Brett's 1979 paper: Ehrenkranz, N. J. and S. J. Pfaff (1979). "Growth of hospital infection control programme and the infection control nurse." J R Soc Med 72(12): 888. https://doi.org/10.1177/014107687907201204 Our top papers   Martin's favourite paper: Wolfensberger, A., L. Clack, S. von Felten, M. Faes Hesse, D. Saleschus, M. T. Meier, K. Kusejko, R. Kouyos, L. Held and H. Sax (2023). "Prevention of non-ventilator-associated hospital-acquired pneumonia in Switzerland: a type 2 hybrid effectiveness-implementation trial." Lancet Infect Dis 23(7): 836-846. https://doi.org/10.1016/S1473-3099(22)00812-X Phil's favourite paper: Peel, T. N., S. Astbury, A. C. Cheng, D. L. Paterson, K. L. Buising, T. Spelman, A. Tran-Duy, S. Adie, G. Boyce, C. McDougall, R. Molnar, J. Mulford, P. Rehfisch, M. Solomon, R. Crawford, T. Harris-Brown, J. Roney, J. Wisniewski, R. de Steiger and A. T. Group (2023). "Trial of Vancomycin and Cefazolin as Surgical Prophylaxis in Arthroplasty." N Engl J Med 389(16): 1488-1498. https://doi.org/10.1056/NEJMoa2301401 Brett's favourite paper: Seidelman, J. L., C. R. Mantyh and D. J. Anderson (2023). "Surgical Site Infection Prevention: A Review." JAMA 329(3): 244-252. https://doi.org/10.1001/jama.2022.24075

In this week's episode Phil and Brett mull over their wishlists for what they would want in a perfect IPC world. They turn out to be a pretty undemanding pair.. not. However they both see a future in which their wishes could become true. Unsurprisingly AI and automated surveillance loom large in their thoughts.

In this episode, Brett and Martin discuss a paper they were recently involved with - a systematic review and meta-analysis on prior room occupancy and the risk to the next person. This paper has been recently published in Infection, Disease and Health. Findings provide some evidence to help inform a risk management approach when determining patient room allocation. The risk of pathogen acquisition appears to remain high, supporting the need for continued investment in this area. Here is a link to the paper. In our discussion, we also mentioned a paper about nurses views on the environment and risk: Mitchell, B. G., Russo, P. L., Kiernan, M., & Curryer, C. (2021). Nurses' and midwives' cleaning knowledge, attitudes and practices: An Australian study. Infection, disease & health, 26(1), 55-62. Link here: Nurses' and midwives' cleaning knowledge, attitudes and practices: An Australian study  

In this week's episode, Martin talks to Dr Jon Otter, epidemiologist, scientst, blogger and Joint Director of Infection Prevention and Control at Guy's and St Thomas' NHS Foundation Trust in the UK. We discuss a session at the recent ICPIC conference on the problems posed by plasmids in terms of outbreak detection, increasing antimicrobial resistance and environmental reservoirs. You can read more about Jon's thoughts in his excellent blog post at https://reflectionsipc.com/2023/09/14/cpe-and-plasmid-transfer-in-hospitals-what-can-we-do-a-rapid-reflection-from-icpic-2023/#more-5141   A paper we discuss from Kalisvar Marimuthu and colleagies can be found here https://www.nature.com/articles/s41467-022-30637-5 You can listen to Kalis discussing it on a previous podcast in our genomics collection here: https://infectioncontrolmatters.com/topics/methodology/

In this episode, Brett talks to Martin about a recent paper on the potential pitfalls of ice machines and following manufactures' instructions.   The paper we discuss is called "How clean is your ice machine?"   This paper was published in the journal of hospital infection: https://www.sciencedirect.com/science/article/abs/pii/S0195670123002700

In this episode, Martin talks to Dr Jinny Moore from the National Health Security Agency in England about detecting pathogens in the ICU environment. They discuss a recent paper where whole-genome sequencing (WGS) on presumptive S. capitis NRCS-A isolates was collected from infants admitted to nationwide NICU and from environmental sampling in two distinct NICUs. The discussion includes details on the approach to sampling (neonates and environment).   Papers discussed: Detection, survival, and persistence of Staphylococcus capitis NRCS-A in neonatal units in England https://www.journalofhospitalinfection.com/article/S0195-6701(23)00234-7/fulltext   Other papers of interest: Laurent F, Butin M. Staphylococcus capitis and NRCS-A clone: the story of an unrecognized pathogen in neonatal intensive care units. Clin Microbiol Infect. 2019;25:1081-5. https://www.ncbi.nlm.nih.gov/pubmed/30928561 Butin M, Martins-Simoes P, Rasigade JP, Picaud JC, Laurent F. Worldwide Endemicity of a Multidrug-Resistant Staphylococcus capitis Clone Involved in Neonatal Sepsis. Emerg Infect Dis. 2017;23:538-9.https://www.ncbi.nlm.nih.gov/pubmed/28221122 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382751/pdf/16-0833.pdf Butin M, Martins-Simoes P, Pichon B, Leyssene D, Bordes-Couecou S, Meugnier H, et al. Emergence and dissemination of a linezolid-resistant Staphylococcus capitis clone in Europe. J Antimicrob Chemother. 2017;72:1014-20. https://www.ncbi.nlm.nih.gov/pubmed/27999045 Van Der Zwet WC, Debets-Ossenkopp YJ, Reinders E, Kapi M, Savelkoul PH, Van Elburg RM, et al. Nosocomial spread of a Staphylococcus capitis strain with heteroresistance to vancomycin in a neonatal intensive care unit. J Clin Microbiol. 2002;40:2520-5. https://www.ncbi.nlm.nih.gov/pubmed/12089273 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC120592/pdf/1550.pdf

This week, Martin talks to Dr Jennifer Meddings, Associate Professor at University of Michigan Health and Internist at Ann Arbor about a recently published survey looking at what interventions are commonly used to prevent device-associated infections. We discuss the findings and focus in on prevention of urinary catheter-associated infections and new devices that may have an impact. The paper can be found here: Saint, S., M. T. Greene, S. L. Krein, K. E. Fowler, K. A. Linder, D. Ratz & J. Meddings (2023) What US hospitals are doing to prevent common device-associated infections during the coronavirus disease 2019 (COVID-19) pandemic: Results from a national survey in the United States. Infect Control Hosp Epidemiol, 10.1017/ice.2023.65, 1-7. https://www.ncbi.nlm.nih.gov/pubmed/37259703 Other areas and papers that we discuss are here: New tools that have been developed and piloted in a large surgical collaborative in Michigan, in our project called SUCCESS:  Surgical Urinary Catheter Care Enhancement Safety Study, which has focused on improving urinary catheter safety even beyond CAUTI prevention, including focus on reducing unnecessary use for several common elective procedures, standardizing diagnosis and management of urinary retention, and practices to reduce traumatic injury from catheters and improve success on first catheterization attempt:   https://msqc.org/success/. Kuriyama, A., K. E. Fowler, J. Meddings, H. Irie, D. Kawakami, H. Iwasaki, M. Sakuraya, K. Katayama, Y. Tokuda & S. Saint (2019) Reducing unnecessary urethral catheter use in Japanese intensive care units: A multicenter interventional study. Infect Control Hosp Epidemiol, 40, 1272-1274. https://www.ncbi.nlm.nih.gov/pubmed/31558172 Patel, P. K., A. Gupta, V. M. Vaughn, J. D. Mann, J. M. Ameling & J. Meddings (2018) Review of Strategies to Reduce Central Line-Associated Bloodstream Infection (CLABSI) and Catheter-Associated Urinary Tract Infection (CAUTI) in Adult ICUs. J Hosp Med, 13, 105-116. https://www.ncbi.nlm.nih.gov/pubmed/29154382 Patel, P. K., A. Gupta, V. M. Vaughn, J. D. Mann, J. M. Ameling & J. Meddings (2018) Review of Strategies to Reduce Central Line-Associated Bloodstream Infection (CLABSI) and Catheter-Associated Urinary Tract Infection (CAUTI) in Adult ICUs. J Hosp Med, 13, 105-116. https://www.ncbi.nlm.nih.gov/pubmed/29154382 Meddings, J., S. Saint, S. L. Krein, E. Gaies, H. Reichert, A. Hickner, S. McNamara, J. D. Mann & L. Mody (2017) Systematic Review of Interventions to Reduce Urinary Tract Infection in Nursing Home Residents. J Hosp Med, 12, 356-368. https://www.ncbi.nlm.nih.gov/pubmed/28459908

In this episode, Martin Kiernan talks to Dr Giorgia Gon, Assistant Professor of Epidemiology, London School of Hygiene and Tropical Medicine about a briefing paper that  identifies research priorities for healthcare cleaning in resource-limited settings. We discuss the process of determining the priorities, the groups involved and the final areas that should be targeted with research funding, including cost-effectiveness, the use of biocides or detergents and minimum requirements. You can find a copy of the CLEAN Briefing here Other papers of interest: 1. Cross S, Gon G, Morrison E, Afsana K, Ali SM, Manjang T, et al. An invisible workforce: the neglected role of cleaners in patient safety on maternity units. Glob Health Action. 2019;12:1480085. https://www.ncbi.nlm.nih.gov/pubmed/31154993 2. Gon G, Kabanywanyi AM, Blinkhoff P, Cousens S, Dancer SJ, Graham WJ, et al. The Clean pilot study: evaluation of an environmental hygiene intervention bundle in three Tanzanian hospitals. Antimicrob Resist Infect Control. 2021;10:8. https://www.ncbi.nlm.nih.gov/pubmed/33413647 3. Storr J, Kilpatrick C, Lee K. Time for a renewed focus on the role of cleaners in achieving safe health care in low- and middle-income countries. Antimicrob Resist Infect Control. 2021;10:59. https://www.ncbi.nlm.nih.gov/pubmed/33762000

In this episode, Martin talks to Giovanni-Battista Fucini about a recent paper from Germany that examined infection rates in critical care in which it was reported that hospitals without sinks in patient rooms have lower infection rates. Newer hospitals in Germany tend not to have sinks in the patient rooms in ICU. The paper we discuss is here: Giovanni-Battista, F., C. Geffers, F. Schwab, M. Behnke, W. Sunder, J. Moellmann & P. Gastmeier (2023) Sinks in patient rooms in the ICU are associated with higher rates of hospital-acquired infections. A retrospective analysis of 552 ICUs. J Hosp Infect, 10.1016/j.jhin.2023.05.018. https://doi.org/10.1016/j.jhin.2023.05.018 Other papers of interest are: Kotay, S. M., H. I. Parikh, K. Barry, H. S. Gweon, W. Guilford, J. Carroll & A. J. Mathers (2020) Nutrients influence the dynamics of Klebsiella pneumoniae carbapenemase producing enterobacterales in transplanted hospital sinks. Water Res, 176, 115707. https://www.ncbi.nlm.nih.gov/pubmed/32224328 Constantinides, B., K. K. Chau, T. P. Quan, G. Rodger, M. I. Andersson, K. Jeffery, S. Lipworth, H. S. Gweon, A. Peniket, G. Pike, J. Millo, M. Byukusenge, M. Holdaway, C. Gibbons, A. J. Mathers, D. W. Crook, T. E. A. Peto, A. S. Walker & N. Stoesser (2020) Genomic surveillance of Escherichia coli and Klebsiella spp. in hospital sink drains and patients. Microb Genom, 6. https://www.ncbi.nlm.nih.gov/pubmed/32553019 Mathers, A. J., K. Vegesana, I. German Mesner, K. E. Barry, A. Pannone, J. Baumann, D. W. Crook, N. Stoesser, S. Kotay, J. Carroll & C. D. Sifri (2018) Intensive Care Unit Wastewater Interventions to Prevent Transmission of Multispecies Klebsiella pneumoniae Carbapenemase-Producing Organisms. Clin Infect Dis, 67, 171-178. https://www.ncbi.nlm.nih.gov/pubmed/29409044 Grabowski, M., J. M. Lobo, B. Gunnell, K. Enfield, R. Carpenter, L. Barnes & A. J. Mathers (2018) Characterizations of handwashing sink activities in a single hospital medical intensive care unit. J Hosp Infect, 100, e115-e122. https://www.ncbi.nlm.nih.gov/pubmed/29738784 Kotay, S., W. Chai, W. Guilford, K. Barry & A. J. Mathers (2017) Spread from the Sink to the Patient: In Situ Study Using Green Fluorescent Protein (GFP)-Expressing Escherichia coli To Model Bacterial Dispersion from Hand-Washing Sink-Trap Reservoirs. Appl Environ Microbiol, 83. https://www.ncbi.nlm.nih.gov/pubmed/28235877 Garvey, M. I., N. Williams, A. Gardiner, C. Ruston, M. A. C. Wilkinson, M. Kiernan, J. T. Walker & E. Holden (2023) The sink splash zone. J Hosp Infect, 135, 154-156. https://www.ncbi.nlm.nih.gov/pubmed/36870392

Martin chats to Phil in Melbourne following a recent presentation. Yes, two old farts reminiscing about the days of wearing out the boot leather collecting surveillance data talk with envy about the potential of HAI surveillance in the era of the electronic medical record, automation and artificial intelligence. Phil refers to data in these two publications: Designing Surveillance of Healthcare-Associated Infections in the Era of Automation and Reporting Mandates The prevalence of healthcare associated infections among adult inpatients at nineteen large Australian acute-care public hospitals: a point prevalence survey

We discuss One Health in this episode with Professor Tom Riley, using C.difficile as the example of explaining why the concept of One Health is so important.   Tom is a Fellow of the Royal College of Pathologists, the Australian Society for Microbiology, the American Academy of Microbiology, the Society for Healthcare Epidemiology of America and the Faculty of Science of the Royal College of Pathologists of Australasia, and has published over 400 book chapters and refereed publications.