Life Optimized

This week, I speak with Dr. Elizabeth Sharp, M.D., IFMCP. She is a board-certified Internal Medicine Physician, Institute for Functional Medicine Certified Practitioner and the founder and CEO of Health Meets Wellness. Elizabeth started Health Meets Wellness to make functional medicine more accessible, combining her expertise in healthcare with physical activity, specifically yoga. She is dedicated to helping her patients reach their wellness goals and developed the Health Meet Wellness method with Troy Flanagan, Ph.D. and Susie Parker-Simmons, RDN, specifically to help patients with weight management. In addition to her innovative practice, she is an Assistant Professor at Mount Sinai Hospital. We chat about her holistic approach to health and wellness, focusing on the integration of medicine, exercise, and nutrition to optimize overall well-being and treat autoimmune diseases.In this episode you will:Understand the importance of a personalized approach in treating health conditions.Recognize the role of diet, exercise, and nutrition in optimizing health.Be able to Identify the potential triggers and root causes of autoimmune conditions.Know what questions to ask your provider for the most comprehensive assessmentLearn the key pillars to holistic health Connect with Dr. Elizabeth Sharp:Website: https://healthmeetswellness.com/Instagram: https://www.instagram.com/dr.elizabethsharp/Use code Paulvin10 for a gift!

In today's episode, I speak with Dr. Kamal Obbad, the co-founder of Nebula Genomics. Kamal is a Harvard and Gates-Cambridge Scholar with research experience at Google. Recognizing a gap in the consumer market for Whole Genome Sequencing (WGS), he co-founded Nebula Genomics to democratize access to comprehensive genomic data. Kamal aims to make personal genomics mainstream and accessible. We chat about the significance of whole genome sequencing and its potential to improve health and wellness. Kamal gives us a lesson on what the genome is, the importance of studying the whole genome sequence for health optimization, and why it has previously been so cost prohibitive to secure whole genome sequencing. In this episode you will learn:- Understand the concept of personal genomics and its potential impact on health and wellness.- Learn about the difference between whole genome sequencing and other genetic tests.- Gain knowledge about the complexity of DNA and the importance of non-coding regions in genetic analysis.- Recognize the limitations and concerns associated with genetic testing and the need for genetic counseling.- Explore the future possibilities of DNA sequencing and its role in personalized medicineLearn more about Nebula Genomics and Kamal's work: nebula.org

In today's episode, I talk with Kirsty Godso, Nike trainer and entrepreneur, about optimizing workouts and diet for maximum results. We discuss what women need to know when looking at their workout planning, the role of supplementation in fitness, and the impact of nutrition on overall health. Kirsty shares her personal journey in the fitness industry and highlights the need for trainers to adapt their programs to individual needs. We also touch on the benefits of high-intensity workouts, the challenges of balancing hormones in active females, and the importance of outdoor time for mental health. Show Highlights:The key ratio for high-intensity workouts to see results What women need to know about high-intensity workoutsThe latest in supplementation for muscle recovery and performance enhancementHow to integrate new routines to enhance sleep and reduce brain fogConnect with Kristy:madeof.comkirstygodso.comConnect with Dr. Paulvinhttps://doctorpaulvin.com/

Schlidt is the cofounder and managing partner at Palo Santo, a venture capital fund focused exclusively on the advancement of psychedelic therapies for the treatment of mental health disorders and beyond. Based on his own experience with severe depression as a teenager, Schlidt's goal is to steward the most efficacious psychedelic therapies towards FDA approval so that patients may safely, legally, and affordably access these medicines. He has deployed $25 million into 20 companies including Gilgamesh, Journey Clinical and Sensorium.Show Highlights:-The potential of psychedelics for mental health treatment.-Tim's story leading to investment in psychedelics.-Why to practice safe and supervised use of psychedelics in treatment.-Legal and ethical considerations around the use of psychedelics.-What are challenges in developing psychedelics?-Predicitons for psychedelics in mainstream medicine.-Psychedelics for therapeutic and personal growth.

Katrine is a health practitioner, author, researcher, and heavy metals detoxification specialist. After growing up in Russia and being negatively affected by radiation fallout from Chernobyl, she had to find her own path to health. She gained a wide knowledge of natural methods for detoxifying and rebuilding the body. Now she helps individuals achieve their own health goals through the combination of state-of-the-art technology, nutrition, and holistic healing. Show Highlights: -Katrine's journey of personal transformation in health. -How to prepare for radiological tests. -The current rise of bioregulators. -A deep dive into the future of supplements. -What are the long-lasting effects of neurofeedback? -Analyzing brain wave patterns.

Summary Join me in conversation with Hannah Went, a leading figure in epigenetics research, as we explore the science behind biological age testing and its potential impact on personalized healthcare. Hannah attended the University of Kentucky and graduated with a degree in Biology. Through work in the integrative medicine industry, Hannah saw an opportunity for methylation-based age diagnostics and started TruDiagnostics in 2020. TruDiagnostic is a company focusing on methylation array-based diagnostics for life extension and preventive healthcare serving functional medicine providers. Since TruDiagnostic's inception, they have created one of the largest private epigenetic health databases in the world with over 30,000 patients tested to date. Hannah has since created Everything Epigenetics where she shares insights on how DNA regulation has an impact on your health. Show Highlights: -What factors influence how your cells age? -Lifestyle tips to promote healthy cellular aging. -What makes one aging test special compared to others? -Misconceptions about biological age clocks. -What is the future of epigenetics?

In today's show, I talk to Jonah Rosner, former NFL sports scientist turned running scientist and high-performance coach. At 25 he was one of the youngest sports scientists in NFL history for the Houston Texans. He also worked across Major League Soccer at Austin FC, the NBA, and NCAA college basketball at University of Texas where he also received his master's degree in exercise physiology. Jonah specializes in using the latest sports science technology and testing to individualize strength and endurance training programs.Show HighlightsHow to improve your VO2 Max.The best supplements to enhance athletic performance.Will nitrates really improve your endurance?How to use Blood Flow Restriction to boost your training.What is biomechanical feedback and how does it help?The best wearables for performance data.ResourcesFollow Jonah - https://www.instagram.com/rosnerperformance/Connect with Dr. Paulvinhttps://doctorpaulvin.com/

In today's show I talk to Pamela Gold, the founder of PRTL (formerly HACKD Fitness) NYC's first biohacking fitness studio, author of Find More Strength: 5 Pillars to Unlock Unlimited Power and Happiness and forthcoming book Timeless in Less Time: 12 Weeks to Optimized Fitness for Life, creator of Peace Power Parenting, an online course to support conscious parenting. Pam is an expert in integrated (physical, mental and energetic) fitness, minimum effective dose fitness, and biohacking. Show Highlights:Why you need to practice self-awareness and learn to listen to your body.The positive impact of a daily meditation practice.How to balance work, family, and personal well-being.The unique needs of women in biohacking.How to optimize your health with a data-driven approach.Tools and strategies for more effective workouts.Learning to trust yourself without relying on other people's opinions.It's never too early to teach self-awareness to children.ResourcesVisit PRTL: https://prtl.com/Connect with Dr. Paulvinhttps://doctorpaulvin.com/

In today's show I talk to Wade Lightheart, 3-Time Canadian Natural Bodybuilding Champion, and one of the world's premier authorities on Natural Nutrition and Training Methods. Having majored in Sports Science at the University of New Brunswick, he has authored numerous books on health, nutrition, and exercise which have sold in over 80 countries. Wade is sought out by athletes and high-performance oriented individuals worldwide for his advice on how to optimize their health and fitness levels.Show Highlights:Why bodybuilding is the original biohacking.The biggest three factors that affect your outcomes in health and fitness.How to lose weight sustainably.The connection between resistance training and your metabolism.Why do many people fail with their diets?Ways to extend your lifespan to 100 years old.How to use your unique psychological, emotional, and genetic makeup to your advantage.ResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/

We're continuing the mini-series on Alzheimer's disease, this time with a focus on specific steps you can take to evaluate and reduce your risk of contracting the sickness. Unfortunately, there isn't yet a specific treatment for the disease, but that doesn't mean you can't take action now.Show Highlights:How to test for Alzheimer's before it's too lateLifestyle and nutrition changes you should make immediatelySurprising ways Low Dose Naltrexone can helpWhy you should care about your MicrogliaHow increasing antioxidants in your body may prevent diseaseSupplements that may reduce your risk of Alzheimer'sResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/

In this episode, we're going to discuss the latest insights and biohacking techniques to help improve brain health, with a focus on Alzheimer's disease. Learn about new medicines, supplements, and technology that can help optimize your brain performance.Show Highlights:What causes Alzheimer's disease?Which lab tests can help evaluate potential brain issues and signs of inflammation.What factors can lead to neurodegenerative symptoms.Why memory loss is a common symptom of brain issues.The latest medicines and supplements for treating Alzheimer's diseaseRecommendations for technology you can use in your own home to optimize brain performance.How you can reduce your risk of developing Azheimer's disease.ResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/

In this episode of the Life to Optimize Podcast, Dr. Neil Pop discusses two main topics: bioregulators and a new peptide called SS-31 (or Elamipretide). Bioregulators, which have been around since the Cold War, are small proteins that work on specific DNA sites to regulate gene expression and DNA methylation, promoting health and longevity. SS 31 is a mitochondrial peptide with antioxidant and anti-inflammatory properties, currently undergoing extensive research. It shows promise in heart health, tendon and joint healing, and potential benefits for Alzheimer's and brain health. Show Highlights:What are bioregulators?Ideal dosages and duration for taking bioregulators.The best place to get bioregulators and peptides.What is SS-31 and how can it help you?Can Elamipretide help your brain and prevent Alzheimer's?The surprising benefits of SS-31 and other similar peptides.ResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/

Today's episode is all about fertility. We'll be discussing various techniques to boost fertility, and the potential negative effects of birth control pills on female hormones. Cutting-edge stem cell treatments and other advancements are also discussed. We'll also cover the impact of inflammation and insulin resistance on mitochondrial function, and what that means for fitness and overall health. Show Highlights:How to reduce inflammation in your body.What can women do to boost fertility?Do stem cell treatments help with infertility?The latest advancements in female fertility treatments.How do birth control pills affect female hormones and fertility?Which lifestyle choices and supplements optimize women's sexual health?ResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/

Today's episode is all about supplements. We'll be discussing different kinds of supplements, which ones you should stay away from, and what makes supplements the way they are. Listen and find out about Spermidine, Urolithin A, and more supplements that can help you in the future.Show Highlights:What are supplements?What kind of supplements are out there?Which one's are good and bad?What's Spermidine?Urolithin A and why it's a strong supplement.What's Butyrate?The two supplements that improve overall health and longevityHow sleep influences supplemental careSupplements mentioned in this episode:SpermidineUrolithin AButyrateResveratrolApigeninMetforminResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/

Dr. Hill is one of the top peak performance coaches in the country. He holds a Ph.D. in Cognitive Neuroscience from UCLA's Department of Psychology and continues to do research on attention and cognition. Research methodology includes EEG, QEEG, and ERP. He has been practicing neurofeedback since 2003.In addition to founding Peak Brain Institute, Dr. Hill is the host of the Head First Podcast with Dr. Hill and lectures at UCLA, teaching courses in psychology, neuroscience, and gerontology.Show Highlights:Learn how you can use neurofeedback to optimize brain functionCan neurofeedback treat ADHD?How does Neurofeedback work?Discover the science behind brain mapping and how it can identify areas of the brain that need attention.How long do the benefits of neurofeedback last?Is it possible to train your brain for higher achievement?What does AI mean for the future of neurofeedback?How to be the best version of yourselfPeak Brain InstitutePeak Brain Institute - Brain Gym & Peak Performance CenterResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/

Ryan Smith received a BA in biochemistry from Transylvania University before heading to medical school in 2013. After passing USMLE Step 1, he decided to leave and open up a pharmacy in the United States that focused on peptide synthesis and formulations for pharmaceutical preparations. That pharmacy, Tailor Made Compounding, became the 4th fastest growing company in healthcare in the US and grew to 80 million in revenue within 3 years. Ryan exited Tailor Made in 2020 to create TruDiagnostic. TruDiagnostic is a CLIA certified lab and health data company which specializes in understanding and reporting insights found through Epigenetic methylation data. TruDiagnostics has also led research in the field with over 30+ clinical trials investigating the best ways to reverse these markers through diet, lifestyle, and prescription interventions. Currently, TruDiagnostic is working with collaborators from Duke, Harvard, Yale, UCSF, Ohio St. and more to uncover new insights from the methylome. TruDiagnostic is also the only commercial company on the market to offer 2nd or 3rd generation aging algorithms which have shown to be more predictive and precise than 1st generation aging clocks.Show Highlights:The current state of anti-aging medicineWhy it's important to measure biological age accurately The best measurement tools for anti-agingWhy you should start testing your biological age as early as possibleWhat data can tell us about the health of an individual beyond agingWhich lifestyle changes will be most helpful for optimizing your health spanResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/TruDiagnostic™ | Advanced Epigenetic Testing

In today's show I talk to Dr. Jay T. Wiles about Heart Rate Variability. We go really deep into all the aspects of HRV. From measuring it accurately to optimizing the factors that affect it. Everything you need to know and more!Dr. Jay T. Wiles is a clinical health psychologist, currently working as the Health Behavior Coordinator at WJB Dorn VA Medical Center in Columbia, SC and the Greenville Outpatient VA Clinic. He has specialized training in health behavior coaching, health assessment, nutritional interventions for mental and physical health, Motivational Interviewing, applied psychophysiology, and consultation. Dr. Wiles works as a consultant for companies/organizations, practitioners, and individual patients on nutritional psychology, health behavior change, applied psychophysiology, and health promotion/disease prevention via complementary and integrative practices.Show Highlights:What is Heart Rate Variability, and why should you measure it?How to measure your Heart Rate VariabilityThe common problems with wearable technologyOptimal ranges for your HRVHow to interpret your biometric dataWhat affects your HRV both positively and negativelyThe surprising connection between HRV and mental healthResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Home - Hanu Health, Inc. - Use code DRPAULVIN for 20% off

Today's episode is a deep dive into peptides. There has been a lot of hype in the Biohacking community around these amazing products. Research is quickly evolving, and keeping up with the latest developments can be difficult. Listen and learn how you can get the most out of peptides to help with your healing and recovery.Show Highlights:What are peptides?How should you take peptides?The best peptides for pain and recoveryAre there risks to taking peptides?The Wolverine Stack – the ultimate in regenerative healingHow to use peptides to lower inflammationWhy you need to pay attention to mitochondrial peptidesPeptides discussed in this episode:Thymosin Alpha 1ThymulinBPC157CJC 1295Melanotan 1 & 2Thymosin Beta 4 (TB4)TB5GHK CopperPentosan PolysulfateAOD9204P21M677TesamorelinKPVMOTS-CSS 31Resources:Connect with Dr. Paulvinhttps://doctorpaulvin.com/

Today's show is a deep dive into exogenous ketones. You'll learn about the latest advances and products, what the benefits are, and what to expect from the upcoming research in this exciting field. I'm joined by Frank LLosa, the CEO and founder of KetoneAid. He's an expert on all things ketones, and I'm excited to have him on today's show to help us learn more!Show Highlights:What are exogenous ketones?Your body's fuel source: glucose or ketonesWhy we should beware of the misinformation in the world about products related to ketones and ketosisHow to understand ketone esters, BHB, and what they do for the bodyThe top benefits of using a ketone product: recovery, mental cognition, and sleepHow exogenous ketones should be taken (Too much of a good thing is NOT good!)What to expect from exogenous ketones in brain activityHow following the keto diet differs from taking exogenous ketonesWhat exogenous ketones can do for high-performance athletes and average athletesHow to be an educated consumer in today's ketone marketWhere the future is headed in the field of exogenous ketonesAn overview of products available at KetoneAid (including their upcoming ketogenic, gluten-free beer!)Where ketone science is headed for the futureResources:Connect with Dr. Paulvinhttps://doctorpaulvin.com/Connect with Frank and KetoneAidwww.ketoneaid.com, Instagram, Facebook, and YouTube

We are diving deep into some of today's most popular scientific breakthroughs in the field of health optimization. My expert guest shares real-life applications from his wealth of knowledge and experience. Join us to learn more about feeling better, looking better, and adding years to your health span!Dr. John Sottery is a Ph.D. scientist who believes that “aging normally” is a disaster. As a 63-year-old with young children, he is incredibly focused on maximizing his health and lifespan. His goal is to teach others how to outperform their chronological age through mitochondrial and cardiovascular health, and he focuses his research on ways to turn on the body's genes that will drive protection and repair. After obtaining his doctorate in chemistry from Duke University, he led project development teams at Procter & Gamble before leaving to start several companies of his own. Through his work today, he attacks problems to understand them at a molecular level to maximize health span, slow down the damage, and accelerate repair in the body. Show Highlights:What is most important to know in optimizing mitochondrial healthWhy we need to understand what damages mitochondria, how to get rid of the damaged ones, and how to create new mitochondria from undamaged onesDr. John's #1 tip for mitochondrial health: Don't eat within three hours of going to bed.How to push your mitochondria with ice baths, saunas, or HIIT workouts–so that your body knows how to recycle defective mitochondriaHow to understand the basics of intermittent fasting, autophagy, antioxidants, and free radicalsWhy broccoli sprouts are good for us–and other foods that turn up Nrf2How the body's phase 2 toxification enzymes work to eliminate carcinogensDr. John's take on getting vital nutrients from food vs. relying on supplementsHow to get the most nutrition out of the broccoli you eatHow fasting, exercise, Resveratrol, and spermidine help turn up autophagyHighlights of the overall benefits of spermidine, including recent research about preventing colon cancer and osteoporosisSources and benefits of ergothioneine (an amino acid found primarily in mushrooms)Why copper can be the difference between mild cognitive impairment and full-blown Alzheimer's (Eat your mushrooms!)Why YOUR body has its own recipe for optimal healthDr. John's final thoughts about how excess fructose, alpha tocopherols, and omega-6 fats are harming peopleResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Connect with Dr. Johnwww.johnsottery.com, Facebook, and YouTubeMentioned in this episode: Dr. Guido Kroemer on YouTube, Nature Wants Us to Be Fat by Dr. Richard Johnson and Drop Acid by Dr. David Perlmutter

There are so many things that we are just beginning to understand about psychedelics and the power of the human brain, and researchers are discovering amazing things about the brain's power over the body. These findings have huge implications for physical fitness, metabolism, and mental health. Join us to learn more from today's expert guest!I'm joined by Shawn Wells, who is a product formulator and expert in the fields of performance nutrition, longevity, fitness, and supplementation. He has formulated over 700 supplements, foods, beverages, and cosmeceuticals, earning him the title “The Ingredientologist.” He is a Registered Dietitian and Certified Sports Nutritionist who has counseled thousands of people on natural health solutions and overcome personal serious health issues, such as Epstein-Barr virus, chronic fatigue syndrome, fibromyalgia, depression, insomnia, obesity, and a pituitary tumor. As a world-renowned thought leader on mitochondrial health, Shawn has spoken on five continents, has been prominently featured in various media outlets, and wrote The Energy Formula. His expertise can help any health-conscious individual to better manage stress and experience higher performance and more energy by utilizing his practical, holistic solutions. Show Highlights:Why Shawn is inspired to do his work by his natural curiosity, problem-solving abilities, and multiple interestsHow Shawn approaches his business and his life with a delusional perspective of seeing what's possible and where he wants to be in making an impact What we need to understand about the basics of psychedelicsHow solving our psychological problems can also have a physiological benefit for the bodyWhy SSRI medications are not the long-term solution for many problemsPrecautions to take in using psychedelics properly and doing the integration workWhat Shawn recommends when starting with psychedelics like MDMA, ketamine, and psilocybinWhy is there a huge energy cost to the body in NOT living your truthWhat Shawn sees as “the next thing” that's comingHow neuroplasticity in the brain also brings physio-plasticity to the body in a complete resetHow Shawn explains DHB as it compares to metformin, the most well-known anti-aging drug that's also used for diabetesA rundown of Shawn's new endeavors: an upcoming video course on The Energy Formula and his work on a new caffeine derivativeResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Connect with ShawnWebsite (sign up for his free, weekly newsletter), Instagram, and BookMentioned in this episodeDr. Matthew Cook, www.drinkupdate.com, and www.muscletech.com

Welcome! I'm joined by Joey Thurman, whose new book is titled The Minimum Method: The Least You can do to be a Stronger, Healthier, Happier You. Joey is a celebrity trainer, fitness expert, and bestselling author who lives in the Chicago area. He is here to share lifestyle and fitness tips, along with workout do's and don'ts. Join us to learn more!Show Highlights:What inspired Joey to address the “minimum” in getting people off the couch and interested in better health How Joey's book breaks down the “how” in helping people achieve their goalsWhy “less is sometimes more” when it comes to trainingHow to begin a full-body workout routine that will bring big benefitsWhy “training to failure” is not the best workout approachWhy most specific eating plans will only be effective for 1-2 weeksHow to approach nutrition with a plan for “adding the minimum to get to your maximum”How to understand macronutrients and micronutrientsJoey's customized guidelines for protein intake for good health–and how to add in healthy carbs and fatsJoey's take on the whey protein vs. pea protein debateWhat we should know about gut health: elimination diets, fiber, and probioticsHow Joey works with his clients in workout recovery, especially in the use of cryotherapy, sauna, breathing, and moreWhat NOT to do in the gym (i.e., exercises that don't work!)Exercises that we SHOULD do in the gym–with intentionWhat to do to be the strongest, healthiest, happiest youWhat inspired Joey to write The Minimum MethodResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Connect with JoeyWebsite, Instagram, and New Book (available for pre-order and coming out on December 27, 2022)

Joining me for today's show is Dr. Joe Lipsky, who shares helpful tips to optimize sports performance and recovery. He explains zone training, how to do it appropriately, and his approach to sports injuries and treatment. Dr. Joe Lipsky obtained his BS in Applied Psychology from Farmingdale University and his Doctor of Physical Therapy from Columbia University Medical School. He uses his combined experiences from his doctorate program and continuing education to deliver to his clients a unique blend of rehabilitation and performance therapy. At Reload Physical Therapy and Fitness, Joe specializes in helping endurance athletes overcome injuries and improve their performance and has helped clients complete their first marathons, 100-mile ultra-endurance races, and Ironman competitions. When Joe isn't working, he loves playing golf, doing his Ironman training, and traveling to new places. Show Highlights:How Joe became interested in physical therapy and working with endurance athletesWhat we should be aware of in cardio training to meet physical activity guidelinesHow Joe explains the basics of Zone Training and how to achieve maximum benefitsHow to determine max heart rate (220 - your age= max heart rate) The biggest mistakes people make in training for competitive sportsWhy wearables are important for monitoring heart rate while trainingWhat Joe recommends regarding low-intensity workouts, high-intensity workouts, and workout recovery with his clientsWhat it means to hit your “max workout”How to use the acronym SNAPSSS (Smoking, Nutrition, Alcohol, Physical Activity, Sleep, Stress, and Social Connections) to remember the components of healthWhy it's important to target different body areas in strength trainingThe most common problems that lead to leg and shoulder injuriesThe one thing that Joe wishes everyone knew about training and recoveryWhat Joe sees coming in the future for physical training and exercise and his opinion on telehealth physical therapyResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Connect with Dr. Joe and check out Reload Physical Therapy and Fitnesshttps://www.reloadpt.com, Reload Instagram, Dr. Joe Instagram, and EmailOther resources mentioned: https://shop.thebrrrn.com and www.prtl.com

Today's show takes a holistic look at the human body as a whole vessel made of physical, mental, spiritual, and emotional parts. My guest and I are discussing a variety of life optimization tips around nutrition, workouts, cold/heat exposure, and recovery. You're sure to find lots of helpful information that you can use to optimize your life. Join us to learn more! Dr. Tyler Jean is a naturopathic physician who has always been interested in the human body and holistic medicine, and he is passionate about the importance of food as medicine, while inspiring others to embrace healthier lifestyles. A former Division-1 athlete and neuroscience researcher, Dr. Tyler went on to complete his medical education at the National University of Natural Medicine in Portland, OR. As a naturopathic doctor, Tyler takes a more integrative and preventative approach to healthcare. This is also the approach that Tyler currently uses through his popular Instagram platform, @tylerjean07, where he empowers his audience with healthy recipes, educational info, brand recommendations, inspiration, and more.Show Highlights:Why Dr. Tyler felt out of alignment with traditional medicine's approach in pathologizing disease, treating disease, and managing symptomsWhat it takes to become a naturopathic doctor as far as education, regulations, and licensureHow our food affects our health, becomes our medicine, and communicates with our genesAny diet that focuses on micro nourishment from whole, unadulterated, real foods is better than the standard American dietWhy improved health requires small nutritional changes over time and an awareness of how different foods affect youWhy we all have attitudes, fears, and stress around food beyond simple nutritionWhy Dr. Tyler begins with patients doing an elimination diet and reducing problematic foodsSuggested foods to improve health: fatty fish with Omega-3 fatty acids, fiber, spices and herbsImportant do's and don'ts in the kitchen regarding plasticsHow pollutants and toxins affect the body–and how sauna treatments can helpWhat to look for in the most effective sauna treatmentsBenefits to the body in sauna, hot baths, and cold plungesHow our bodies work to generate heat in response to deliberate cold exposure–and produce more beneficial mitochondriaDetails about maximizing cold exposure benefits at homeHow Dr. Tyler has worked to maximize his visibility as a naturopathic doctor and entrepreneurResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Connect with Dr. TylerWebsite and InstagramRecipe cookbook: https://tylerjean.com/recipe-book-landing-page/Nutrition Course: https://tylerjean.com/course/TherasageUse the code FUNCTIONALFOODS to save 10%.

Today's guest is a master of many talents who has used health and life optimization tools in all facets of his life, epitomizing the idea that challenges in life are there to be overcome. We are talking about all things health and fitness with tons of helpful information you can use. Join us!Jimmy Martin is a NYC-based entrepreneur and creative currently serving as co-founder and head of fitness at Brrrn, the health and wellness behind The Today Show-touted Brrrn Board. Jimmy has over a decade of experience working as a health and wellness professional, both as a group exercise instructor and personal trainer to C-Suite executives and various celebrities in television, film, and fashion. Previously, Jimmy worked as an advertising copywriter, greeting card writer, playwright, and executive producer under his production company, Mayamo Jimmy Productions. Jimmy is a 2007 alumnus of George Mason University, where he was a member of the Division I wrestling program. He graduated with a BA in Interpersonal and Organizational Communication and minored in Business Management. Jimmy holds his national personal trainer certification from the American Council of Exercise. Show Highlights:How a common thread throughout Jimmy's life and work is his love for taking on tough challengesHow Jimmy uses humor to foster connection and compatibilityWhy Jimmy went the cold route with his exercise brand to create a completely different workout environment–and literally started it all in a beer fridgeWhy the discomfort we feel in conversations around death have parallels for Jimmy to the discomfort we experience in cool-temperature exerciseHow a 50-degree exercise environment, cold plunges, and sauna therapy utilize hormesis, or positive stress, on the human bodyHow to use cold showers, and alternating hot and cold, as the basic entry point for cold therapyHow Jimmy built the Brrrn brand in the beginning and differentiated Brrrn from the typical boutique fitness establishmentHow Brrrn adapted during the pandemic and expanded with the Brrrn Board and online workoutsHow lateral movement exercise, like the Brrrn Board, improves core strength, balance, coordination, and overall athletic performanceHow Jimmy and Brrrn are launching the first accredited slide board training for professional trainers and coachesHow health optimization and testosterone replacement therapy have led to the upcoming birth of Jimmy's baby boy through an IVF procedureResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Connect with Jimmy and BrrrnInstagram (Jimmy) and Instagram (Brrrn)

Human behavior in its many-nuanced forms governs every social interaction that we have. So many of our interactions and communications are nonverbal, and both sides depend on perceptions and context clues to make meaning out of those interactions. This aspect of human psychology is fascinating, and we are jumping into this topic on today's show. Join us to hear more from today's guest!Blake Eastman is the founder of The Nonverbal Group, which he started in NYC in 2009 as a behavioral research and education company. Through their large scale studies to record, dissect, and study human behavior, they help entrepreneurs, executives, and poker players understand the human psychology of reading people. Blake's background includes a stint as an adjunct psychology professor at City University of New York (CUNY) and time spent playing poker professionally. Show Highlights:What The Nonverbal Group does–and how it applies to real lifeHow The Nonverbal Group originated from Blake's childhood experience with anxiety about social interactions and his later frustration with the academic constraints around psychologyWhy Blake calls video “the main reality” in reading peopleWhy reading people's behavior has more to do with the invisible social norms than their movements and mannerismsHow most of human interaction comes down to perceptionWhat it means to control the context around you and control the narrativeHow social media is impacting human behaviorHow artificial intelligence is playing into human behavior and interactions–and how things will change in the next few years Why Blake can't help “noticing” what people do in every social situationHow someone can improve the perception of themselves in the entrepreneurial spaceWhy much of our anxiety and stress come from how we perceive ourselves in social interactionsFoundational tips from Blake about showing up on video and communicating effectivelyBlake's best tips for Saturday night poker playersResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Connect with BlakeWebsiteVisit their website to find out more about The Social Edge, a new 90-day program beginning January 10, 2023.

Living a life of optimum health and vitality is what everyone desires, but how much do we really know about achieving that goal? My guest today is on the cutting edge of biochemical research regarding the most critical foundations of the body's ability to resist disease, repair cellular damage, and protect neural pathways. It all comes down to plasmalogens and their marvelous work in the body. Join us to learn more!Dr. Dayan Goodenowe is a scientist at Prodrome. He is a researcher and inventor of biochemical mechanisms. His curiosity about the biochemistry of life is as insatiable today as it was 30 years ago. In those 30 years, Dr. Goodenowe invented and developed advanced bio-information technologies, designed and manufactured novel supplements, and identified prodromes of numerous diseases including Alzheimer's, dementia, Parkinson's disease, multiple sclerosis, ALS, schizophrenia, bipolar disorder, depression, and numerous cancers. Show Highlights:Get to know Dr. Goodenowe and his background in psychiatry and the biomechanics of diseaseHow Dr. Goodenowe's research shows the relationship between the decrease of plasmalogens in the brain and muscles over time and several neurological diseases How Dr. Goodenowe's work is essentially human bioengineering to optimize health and function through strategic supplementationAn explanation of metabolomics and how they work in the bodyWhy genes don't cause disease but expose the diseases we are unable to make adaptations forHow biochemical engineering can silence genetic predispositions to combat diseaseWhat plasmalogens are, what makes them unique, and what they do in the bodyWhy babies need the plasmalogens in breast milk to help prevent autism and problems in early childhood developmentWhy taking plasmalogens leads to improvements in sleep, calmness, neuromuscular performance, muscle recovery, and cognitive functionHow blood tests can determine plasmalogen levels–and why they should be done around age 40-50Dr. Goodenowe's recommendations for taking plasmalogens, specifically the ProdromeNeuro and ProdromeGlia oilsHow concussions and brain inflammation are only remedied by feeding them critical components, like plasmalogensHow plasmalogens help in cholesterol transport and oxidative stressWhat Dr. Goodenowe sees as the future of oral plasmalogens–and who should not take themResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Find out more about Dr. Goodenowe's researchWebsiteFind out more about Prodrome and order supplements Prodrome (Use the discount code “NPaulvin25.”)

Today's episode takes a close look at breathwork, contrast hot/cold therapy, and the many benefits they bring to our bodies. The physical and mental improvements from these simple hormetic practices are mind-boggling and important for us to understand. Today's expert guest breaks down the basics of what we need to know for optimal health. Join us to learn more!Avi Greenberg is a certified Wim Hof instructor who teaches private and corporate breathing and does mindfulness coaching. He helps others achieve better lifestyles by improving their relationship with stress, and he works with in-person and remote clients on breathwork, sauna usage, and cold submersion. His next worksop is in San Diego at the end of October. Show Highlights:The basics of Wim Hof breathingHow someone can get started with Wim Hof breathingHow using mouth tape for nasal breathing at night can improve your breathing, circulation, sleep quality, and immune systemAvi's recommendations for breathwork for stress management (Hint: It's all about the exhale!)Why breathing in six cycles per minute is the sweet spot for the body's nervous system–and brings multiple health benefitsHow to get started with cold exposure therapy, which boosts white blood cell and dopamine production along with numerous other benefitsHow cold showers can yield similar results and be done at home to push to a higher threshold for everyday stressHow contrast therapy (alternating hot and cold) brings added benefits to the bodyHow ending contrast therapy with cold puts the body in a relaxed and calm state because the heart rate slows downThe recommended numbers for contrasting sauna and cold plunge therapyHighlights of the important safety considerations for contrast therapy and breathwork practicesResources:Connect with Dr. Paulvinhttps://doctorpaulvin.com/Connect with AviWebsite and Instagram XPT Oxygen Advantage Wim Hof Method Remedy Place Prtl Books mentioned by Avi The Oxygen Advantage by Patrick McKeownWhat Doesn't Kill Us by Scott CarneyThe Wedge by Scott Carney

Hot Topic Alert! Today's episode takes a deep dive into weight loss and obesity medicine. These topics always generate relevant and interesting conversations. We will also look into the world of hormone balancing for males and females and answer the most common questions that come up. Join us for the conversation!Dr. Kyle Gillett is a specialist in hormones and obesity medicine. He provides holistic, individualized care to his patients, and his practice includes preventative medicine, aesthetics, sports medicine, hormone optimization, obstetrics, fertility, integrative medicine, and precision medicine, including genomics. He believes that each human is a unique creation that requires attention to the body, mind, and soul to achieve optimal health. Kyle enjoys caring for others using shared decision-making and an evidence-based, patient-centered approach. He is active in obesity medicine organizations and firmly believes that food is medicine and exercise is medicine. Dr. Gillett ascribes to six pillars of health: exercise, diet, sleep, stress, sunlight, and spirit; these are more powerful than any medication or supplement. He enjoys spending time outdoors on their farm with his wife, two sons, and their two wolfhounds. Show Highlights:Is there ONE best diet recommended for optimal weight loss?Why the best general guidelines for a healthy diet are to decrease liquid calories and processed foods while increasing the intake of whole foodsWhat Dr. Kyle looks for within lab results to get the big picture of health (Insulin resistance is a biggie!)How a DEXA scan can help track a person's progress over time in body compositionWhat Dr. Kyle views as the key factors in treating insulin resistanceThe most important lifestyle changes patients can make on the path to optimal healthAn explanation of Zone 2 exercise and its importanceWhy mitochondrial health is vital for wellnessImportant factors to consider about fastingDr. Kyle's opinion on non-DEXA-scan measures of visceral fat and body fat compositionWhat leptin resistance indicates regarding weight loss and overall healthWhat to know about testosterone and estrogen and their lab testsImportant considerations in SHBG (sex hormone-binding globulin) levelsDr. Kyle's favorite go-to natural supplements to elevate testosterone levels: carnitine, creatine, and omega-3sDr. Kyle's stance on estrogen levels in men and testosterone levels in womenWhat Dr. Kyle recommends in hormone replacement therapy for womenResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Connect with Dr. Kyle Website, Instagram, Facebook

Today's episode, my first solo show, is a deep dive into peptides, bioregulators, and how they interact with other tools in the areas of anti-aging, sports recovery, inflammation, and mitochondrial health. Biohacking technologies have just begun to scratch the surface of understanding all that peptides can do, and this is a rapidly evolving area of health optimization. Let's break down the basics of peptide therapy together.Show Highlights:A basic introduction to peptides, what they do, and how we should take themWhy some peptides have FDA approval and some do notWhy different peptides come in different forms and are administered in various waysHow peptides work well with bioregulatorsA look at common anti-inflammatory and recovery peptides: BPC-157, Thymosin Beta 4, GHK Copper, KPV, Pentosan, and CerebrolysinWhat we know about growth hormone peptides and their benefitsA look at common growth hormone peptides: Tesamorelin, CJC-1295, MK-677, and AOD ResourcesConnect with Dr. Paulvindoctorpaulvin.com

Today's episode focuses on biohacking in the skincare industry. Today's guest shares how innovations in longevity, anti-aging, and health optimization translate into topical products. Join us to learn more!Amitay Eshel is the co-founder and CEO of Young Goose, a biohacking skincare company that uses skin regenerative therapy to correct cellular damage. He has worked with hair care and red light therapy before finding his place in the skincare field. As an Israeli military veteran, he had brain injuries that prompted his interest in biohacking, longevity, and NAD. Young Goose is on the cutting edge of new skincare biohacking innovations. Show Highlights:The role of NAD in the skin and the body's regenerative processesWhat a patient can expect from using an NAD skin creamWhy Young Goose only puts NAD precursors in two of their productsWhy Young Goose's sunscreen is different from most others on the marketHow even artificial light can damage the skin and cause pigmentationWhat to look for in a sunblock (and why you should avoid chemical sunblocks) if you are concerned about your healthWhat to consider in taking NAD suppositories, IVs, and creamsHow peptides are used in Young Goose productsHow hyperbaric technologies are used in skincareHow red light therapies can help with general health and specific skincare issues to help our cells function more optimallyResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Find out more about Young GooseWebsite, Instagram, Podcast

Today's episode focuses on spermidine as a supplement with known benefits in cellular renewal, healthy aging, and beauty. Our expert guest explains what spermidine is, where it's found, and how it can be used to combat the effects of aging. She explains the research and results from the Oxford Healthspan supplement, Primeadine, which is one that I recommend to all my patients. Join us to learn more!Leslie Kenny is an autoimmune disease survivor and certified health coach. She is the founder of Oxford Healthspan and the co-founder of the Oxford Longevity Project. They offer free public service webinars about breakthrough scientific discoveries that are being translated into new protocols that patients can use. Cellular renewal is of special interest to Leslie because of its effect on the aging process. She shares with us how our bodies manufacture and use spermidine, and why most people need a supplement for maximum health and anti-aging benefits. Show Highlights:Why spermidine is of particular use in cellular renewal How our bodies repair themselves through the production of spermidine Why spermidine is produced today in supplement form even though it's present in some foodsThe relation between a healthy gut biome and spermidine productionThe hallmarks of aging and spermidine's effects on osteoporosisWhy spermidine dosage should be personalized to each person's preference Leslie's theory about gluten-free spermidine supplements and the gut biome of each person's maternal lineBenefits of spermidine, which are most notably healing of the gut lining and reducing inflammationHow Leslie has reversed her autoimmune illnesses through diet and supplementsHow spermidine helps in the autophagy process (cellular renewal and recycling), which diminishes as we ageHow spermidine assists in the growth of hair, skin, and nails–and has been linked to the reversal of gray hair!Who should take a spermidine supplement and when they should start taking itHow to get more spermidine through foodsResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Find out more: www.oxfordhealthspan.com, www.primeadine.com Find Primeadine on InstagramFind Oxford Healthspan on InstagramFor email support about Primeadine: support@oxfordhealthspan.com

Welcome to Episode 2 of the podcast! New technologies can give us much detail about our bodies' efficiency and function, but there are many questions. What technologies are most beneficial? Are there affordable options to use at home? How do we use the information to optimize health and wellness? Join us in today's conversation to learn more!Bob Troia, aka “Quantified Bob,” is well known in the personal optimization space. Based in NYC, he is a technology entrepreneur and biohacker focused on the intersection of data-driven citizen science, health and wellness, human performance, and longevity. Bob has been at the forefront of digital innovation and emerging technology for two decades, and he is a prominent voice in the biohacking and quantified self movement. He addresses many present-day issues in the field in his blog, Quantified Self, which can be found on his Website. In addition to speaking at leading international conferences, Bob has appeared on numerous media outlets including CBS News Sunday Morning, PBS Newshour Weekend, National Geographic Explorer, CBC (Canada), SBS-TV (South Korea), Fast Company, Men's Fitness, and Outside Magazine as well as many wellness-related podcasts. He is the co-founder of Awesome Labs, a health, wellness, and emerging technology studio. Show Highlights:How the biohacking movement has evolved over the last ten yearsHow biohacking has become a worldwide phenomenon that people use for various reasons to improve their health and wellnessWhat Bob sees as the current top emerging technologies in the fieldThe importance of doing research before you invest in new technologiesHow high-level athletes can use the available technologies to optimize performanceSimple biohacking modalities people can use without spending big moneyThe benefits of percussive devices and compression therapyNew technologies in electro-muscular therapy and brain-training toolsBob's recommendations regarding supplements, injections, fasts, etc. What to look for in the near future in the field of quantified health ResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Connect with BobWebsite, Instagram, TwitterFind out more about Awesome Labs, their peptide calculator app, and Awesome Breathing

Welcome to the first episode of Life Optimized! Today's focus is on heart health, which is relevant to everyone. My guest shares what we should be doing in 2022 for optimal cardiac health, new tests in the cardiac field, and how red light therapy can be used for heart health and overall well being. Join us to learn more!Dr. Michael Twyman is a board-certified cardiologist focused on the prevention and early detection of heart disease. He completed his cardiovascular training at St. Louis University and completed four years of active duty as an internist at Naval Hospital Beaufort. In private practice since 2012, he utilizes the best that conventional medicine, integrative functional medicine, quantum medicine, and biohacking can deliver to get to the root cause of a patient's cardiovascular issuesShow Highlights:How a normal person with no specific cardiac issues should assess their heart healthThe most beneficial tests to assess cardiac health: Carotid Intima-Media Thickness Test (CIMT) and CT coronary calcium scoreHow a new test, the Cleerly CCT angiogram, can go further in detecting soft plaque in the arteriesWhat an elevated CRP consistently over time says about your cardiac healthOther markers that Dr. Twyman uses to assess cardiovascular health What Dr. Twyman's opinion is of the danger of high LDL cholesterol with no other risk factorsWhy Dr. Twyman believes there is no low cholesterol number that is “too low”How genetic testing factors into tests for cardiac healthTop risk factors for heart disease: age and diabetes When someone should get screened for heart disease beyond normal lab testsThe best changes people can make at home to improve heart health by focusing on exercise, nutrition, sleep, and stress managementA look at the coolest new heart-health technologiesHow to strike a balance between conventional treatment with statins and functional medicine tools and supplementsWhat patients should know about red light therapy, also called photobiomodulation (PBM)What patients can do for mitochondrial healthWhy circadian rhythms play a huge role in cardiac and overall health and wellnessResources:Connect with Dr. Paulvinhttps://doctorpaulvin.com/Connect with Dr. Twymanwww.drtwyman.com and Instagram