Podcasts about shbg

Half a million of you on Instagram. I still can't quite get over that number.To celebrate, this episode is all you — an open Ask Me Anything where I answer the questions you've actually been sending me. No guest, no agenda, just me working through your real questions about hormones, menopause, sexual health, and the stuff nobody explains to you in a normal doctor's appointment.We cover a lot of ground — how I ended up a urologist obsessed with female sexual health in the first place, the myths about hormone therapy I am still correcting in 2026, DHEA, the estrogen patch shortage, why your labs don't always tell the whole story, and yes, the Ferrari engine analogy makes another appearance. If you've been wondering something and never had the nerve to ask your own doctor — there's a good chance I answer it here.In This EpisodeHow I got here. My background as a urologist and how that path led me into female sexual health — a specialty most people don't expect a urologist to end up in.Hormones, menopause, and aging. Why hormones matter so much more than most of us were taught, and what's actually happening in your body during the menopause transition.Hormone therapy myths, corrected. I'm clearing up the misinformation that's still floating around about HRT — including specific questions on risk for women with a Factor V (Factor two) clotting diagnosis.DHEA and vaginal estrogen. What they do, why the estrogen patch shortage is happening, and what to switch to (gels, oral options) in the meantime.Testosterone, decoded. Comparing creams versus injections, how to interpret SHBG, and why I care more about how you feel than what the lab printout says.Progesterone tolerance. What to do when the standard dose doesn't agree with you, and where extended-release formulations fit in.Persistent UTIs on vaginal estrogen. Why they still happen even when you're doing everything "right," and what else might be going on.Weight gain and menopause. What the data actually says — and what gets blamed on hormones that isn't really about hormones at all.Talking about sex — with clients, with partners. A layered, step-by-step way to open the conversation about low libido without it feeling like a confrontation.Individualized care. Why hormone management should never be one-size-fits-all, and how I think about lab testing versus symptoms.What's next. vulvar DHEA, book clubs, and more ways to keep learning together.Subscribe, leave a review, and share this episode with someone who needs it.

Two athletes who worked with bodybuilding coach Bleu Taylor have passed away, raising difficult questions about coaching responsibility, athlete health and knowing when a situation is beyond a coach's role. Dr. Ashley speaks publicly about the loss of her husband and her concerns about his coaching, and Scott, Skip Hill and Andrew Berry break down her message and discuss what responsible coaching should look like. Then we get into your listener questions on mini cuts, first steroid cycles, how quickly compounds build up, Tren Ace vs. Tren E, glycogen loading for competitors with physical jobs, SHBG, Bro Splits vs. Push Pull Legs while dieting, physique critiques and more. Hear Dr. Ashley's full message here: https://www.instagram.com/p/DcJ5BMHSE4o/ 0:00 Dr. Ashley Speaks Out About Bleu Taylor 2:30 Two Former Bleu Taylor Clients Have Passed Away 3:45 Coach-Athlete Relationships & Responsibility 5:40 Knowing the Limits of a Bodybuilding Coach 12:40 What Makes a Responsible Coach? 13:15 Coaching Athletes With Questionable Health 22:45 Staying Healthy in Bodybuilding 24:30 How Common Are Mini Cuts? 34:30 Choosing Compounds for a First Steroid Cycle 38:00 How Quickly Do Steroids Build Up? 41:30 Tren Ace vs. Tren E — Is There a Difference? 43:40 Contest Prep Glycogen Loading With a Physical Job 53:30 Why SHBG Matters 55:20 What Is a Bro Split? 58:00 Bro Split vs. Push Pull Legs While Dieting 1:08:00 Physique Critique - Plus Scott gets SO Confused

Low testosterone in women starts far earlier than anyone tells you — 25% gone by the mid-20s, half by the mid-30s. Liz & Becca break down why testosterone, not estrogen, is the first hormone to go, what oral birth control does to free testosterone and SHBG, why 80% of autoimmune disease shows up in women, and what "normal range" actually means when the reference population is post-menopausal. Both hosts share their own labs, including a total testosterone of 8. *** CONNECT:

Get personalized root-cause care with Empower Functional Health.Learn more at empowerfunctionalhealth.com_____Robert Sikes put the viral sardine fast to a controlled test: five days of eating approximately 18 cans of sardines per day while maintaining roughly 3,000 calories. In this interview, Judy Cho and Robert examine what happened to his weight, blood glucose, ketones, energy, inflammation, hunger, and overall performance—and why his experience differed from the dramatic weight-loss results commonly shared across the keto and carnivore communities.They also review Robert's bloodwork before, immediately after, and several weeks after the sardine challenge, including arsenic, mercury, lead, cholesterol, thyroid markers, and SHBG. The conversation explores whether sardine fasting produces unique metabolic benefits, what may actually drive the rapid changes people report, and how extreme short-term diets can affect metabolic health, binge-restriction patterns, and long-term weight-loss success.We discuss the following: Sardine challenge previewWhy Robert tested sardine fastingEating 18 sardine cans dailyGlucose rose while ketones droppedWhy people do sardine fastRestriction, bingeing, and quick fixesHeavy metals after sardine challengeThe appeal of extreme fasting Should people fear mercury in sardines? _____EPISODE RESOURCESKeto Savage WebsiteKeto Savage YoutubeKetogenic BodybuildingSavage Perspective PodcastKeto Brick_____WEEKLY NEWSLETTER

PCOS Is Now PMOS. What the New Name Changes About How You Get Treated For decades, the diagnosis pointed at your ovaries. Cysts. Fertility. Birth control to regulate the cycle, and a shrug for everything else. This year, that changed. Polycystic ovary syndrome was formally renamed polyendocrine metabolic ovarian syndrome, or PMOS, in a global consensus published in The Lancet. The point was not cosmetic. It was an admission that this was never really a gynecological problem. Dr. Terri sits down with Dr. Cassie Smith, MD, dual board-certified endocrinologist, founder of Modern Endocrine, and author of Fix Your Gut, Fix Your Hormones, recorded on location at the EVEXIAS provider training. Dr. Smith has been making this argument for years, long before the literature caught up: the insulin, the inflammation, and the gut come first. The hormones are downstream. And if you only treat the hormones, you never actually fix anything. The conversation runs from the patient who was thin, had no cysts, had one symptom, and whose insulin nobody ever checked, all the way to what is happening right now with GLP-1s, the telehealth prescribing free-for-all, and the muscle loss almost nobody is monitoring. If you have been told your cycles are irregular and handed a prescription, if you are thin but feel metabolically off, or if you are on a GLP-1 and wondering whether you are doing it right, this one is for you. What you'll discover: 00:00 PCOS is officially renamed PMOS, and why the shift moves the focus off the ovaries entirely 00:59 The six different presentations of PCOS, including lean patients with no cysts and normal testosterone 01:42 The thin patient with one symptom, an irregular cycle, and an insulin level nobody ever ordered 03:33 The metabolic dumpster fire: how gut dysfunction drives estrogen, progesterone, insulin, and cortisol out of balance 04:08 What actually happens when you come off birth control after years of symptom suppression 05:36 The lab panel Dr. Smith runs first, including Free T3, insulin, cortisol, and a gut study 06:28 The unsexy basics: sleep, real food, sunlight, walking, and getting off the phone at midnight 07:29 Delayed childbearing, coming off the pill at 33, and the fertility math nobody explains 09:29 Treating PMOS in perimenopause when fertility is no longer the goal 10:50 Low serum testosterone with high free testosterone, and what low SHBG is telling you 11:50 The estrobolome: the gut bacteria responsible for recycling your estrogen 13:39 Why endocrinology and gynecology both missed this for so long 15:32 Fat cells as a full endocrine organ, and the signals they send when they are overfull 17:29 Ten thousand smoke signals: how inflammatory cytokines confuse your immune system 19:51 Skinny fat explained, and how you can be thin with the metabolic profile of someone who isn't 22:09 GLP-1s: what they do well, and how they are being prescribed badly 22:53 There is no magic bullet, and why your health is rent, not something you own 24:34 Telehealth vial-and-titration prescribing, the gray market, and patients with no follow-up 26:52 Doing it correctly: body composition scans, protein, resistance training, realistic timelines 29:44 GLP-1s slow gut motility. What Dr. Smith does to protect the gut long term 30:05 Fiber, hydration, and the two steps that changed one patient's life before she lost a pound The rename was the easy part. Now somebody has to start treating the whole system. The Dr. Terri Show is presented by EVEXIAS Health Solutions. For more, visit: https://www.evexias.com Connect with Dr. Terri:

Paradigm Peptides owner is headed to prison — and one customer testified that he suffers from “testosterone-induced mania.” Dave Crosland and Scott McNally react to the news story before getting into your questions on TRT Plus, strength compounds, SHBG, high-dose testosterone, Tren, DHB, first cycles and more. 0:00 “Testosterone-Induced Mania”?! 1:00 Dave Is in France 1:45 Paradigm Peptides Owner Sentenced to Prison 2:40 Reacting to the Paradigm Peptides News Segment 9:45 Steroid Cycles for Prius Owners 13:00 What Is a TRT Plus Cycle? 15:00 Best “Dry” Steroids for Strength 19:40 Dave's Fat-Loss Journey 20:00 Jack3d & the Craziest Old-School Pre-Workouts 26:40 Gut Issues & SIBO 30:30 Keep Cycling While Cutting or Take a Health Phase? 35:00 SHBG, Free Testosterone & the Megalin Receptor 37:45 1,000mg Testosterone: Start There or Taper Up? 39:20 Should You Get Back on Gear After a Layoff? 40:15 Can Oral Primo Work as an AI? 41:45 Adding DHB to the Next Cycle 44:20 Is 20 Weeks Too Long for a First Cycle? 46:30 Does DHB Control Estrogen Like EQ? 47:40 Minimum Tren Dose to Transform Your Physique? 49:20 Dealing With Loose Skin After Major Fat Loss 52:40 How to Pick the Right Steroid for Gains 56:00 It's 104 Degrees in France?! UK Blood Work Get your Labs done by Dave in the UK : https://evalbloodanalysis.com/home/ Support the Podcast Patreon — Help keep the show growing. Even $5/month makes a difference. https://www.patreon.com/thinkbigbodybuilding Sponsors TRUE NUTRITION — Custom supplements for serious lifters Use code THINK to save https://www.truenutrition.com/THINK STROM SPORTS — Performance supplements trusted by athletes UK: https://tinyurl.com/ydmbfa54 US: https://stromsportsus.com Supplement Source Canada — Top brand supplements with fast shipping http://www.supplementsource.ca Merch Official THINK BIG Merch — Train, represent, support the brand https://think-big.printify.me/products

In this Huberman Lab Essentials episode, my guest is Dr. Sara Gottfried, M.D., a Harvard-trained, board-certified gynecologist and expert in female hormone health. We discuss the key biomarkers women should track at each stage of life and how cortisol, thyroid hormone, estrogen, progesterone, and testosterone shape energy, mood, metabolism, and long-term disease risk. We also discuss PCOS, the risks and benefits of oral contraceptives, and the shift in brain metabolism that begins in perimenopause. Dr. Gottfried explains actionable tools for hormone and micronutrient testing, nutrition, stress management, and cardiometabolic screening that women can use at any age. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps (00:00:00) Female Hormone Health (00:00:24) Family History, Intergenerational Trauma; Endometriosis, Fibroids, PCOS (00:01:31) Biomarkers by Decade; Teens & Cortisol; 20s & Sex Hormones (00:03:35) Tool: Hormone Test Timing; Micronutrient Testing, Magnesium (00:05:41) Sponsor: LMNT (00:07:17) Tool: Smoothies, Greens Powders & Microbiome (00:08:12) Nutrient Panels, Antioxidants, B Vitamins, Glutathione (00:09:34) Constipation, Thyroid Dysfunction; Trauma & Female Physiology (00:11:50) Tools: Reduce Perceived Stress, Meditation, Yoga, Breathwork (00:13:30) Opportunities by Decade; Androgens & Testosterone Decline (00:14:50) PCOS, Diagnostic Criteria, Hirsutism, Cardiometabolic Risk (00:17:10) Insulin & Glucose; Tool: Continuous Glucose Monitors (00:18:05) Democratizing Health Data (00:18:52) Sponsor: AG1 (00:20:07) Longevity "Don'ts"; Chronic Cardio & Cortisol; Tool: Adaptive Exercise (00:22:46) Oral Contraceptives, Benefits & Ovarian Cancer Risk (00:24:27) Ovarian Cancer Symptoms, Bloating, CA-125 (00:25:51) Oral Contraceptive Risks, Progestins, Inflammation; SHBG & Testosterone (00:29:08) Clitoral Shrinkage; Tools: Alternatives for Painful Periods (00:30:14) Sponsor: Eight Sleep (00:31:32) Menopause & Perimenopause; 30s Hormonal Baseline (00:33:07) Female Brain, Cerebral Hypometabolism & Alzheimer's Risk (00:35:02) Slow Brain Energy, Hormone Therapy; Hot Flashes as Biomarkers (00:36:54) Tool: Coronary Artery Calcium Score Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Seu paciente treina pesado, tem exames "impecáveis" e quase nunca fala sobre uso de atalhos químicos.Até o dia em que chega ao pronto-socorro. Quanto você realmente sabe sobre o paciente que usa anabolizantes?Neste episódio, William Batah e Fernanda Justo recebem a Dra. Luciana Oliveira, endocrinologista pela UFPR, mestre pela UNIFESP e preceptora do ambulatório de endocrinologia do exercício, para destrinchar um tema que a cardiologia não pode mais ignorar. Luciana também lidera uma plataforma de notificação de complicações do uso indevido de hormônios e implantes no Brasil, o que dá ao episódio uma visão rara de quem lida com as consequências reais desse uso na prática.

Should you ever cruise on more than TRT between steroid cycles? In this episode of Blood Sweat & Gear, Skip Hill, Andrew Berry, and Scott McNally break down when a higher cruise dose might make sense, who it doesn't make sense for, and the long-term tradeoffs every enhanced lifter should understand. Along the way, they discuss James Hollingshead's Tampa Pro performance, SHBG, recovering from back injuries, bodybuilding with diabetes, partial reps, and much more. 0:00 Should You Stay Bigger Year-Round? 1:30 Support Blood Sweat & Gear on Patreon 2:20 Andrew Berry Breaks Down the Tampa Pro 5:00 James Hollingshead Was Better Than We Realized 7:40 When Does TRT Plus Make Sense? 10:20 What's the Most Common Cruise Dose? 11:30 Does Age Change the Equation? 17:20 Should You Add Another Compound? 20:30 Loving Bodybuilding vs Chasing More Gear 28:20 Andrew Berry's "Poverty Prep" Strategy 31:24 How Important Is SHBG? 40:40 Recovering From a Back Injury 46:40 Bodybuilding With Diabetes 54:55 The Most Intense Fitness Creators Online 1:03:40 Partial Reps & Intensity Techniques 1:12:00 Behind the Scenes ✅ ✅ ✅ Check out all our Peptide Affiliates at : https://thinkbigbodybuilding.com

This episode explores the opportunities and risks of testosterone optimization, beginning with the US military's decision to screen men over 30 for low testosterone. Dr. Mike Hart and Dr. Jonathan Schoeff discuss why symptoms such as fatigue, low libido, and difficulty changing body composition cannot be interpreted from a single lab value. They examine the importance of free testosterone, SHBG, insulin resistance, visceral fat, estradiol, DHT, fertility, and individualized dosing. The conversation also challenges common measures such as BMI and body fat percentage, emphasizing skeletal muscle mass, visceral adiposity, sustainable health goals, and the minimum effective intervention.   Dr. Jonathan Schoeff is a spinal surgeon and longevity medicine practitioner whose work focuses on hormone health, metabolic optimization, body composition, and individualized health strategy. Through comprehensive laboratory testing, clinical assessment, and personalized treatment planning, he helps clients understand how hormones, insulin sensitivity, muscle mass, visceral fat, lifestyle, and long-term health goals interact. Describing his role as that of a "biological strategist," Dr. Schoeff emphasizes precision over standardized protocols and develops practical plans designed around each person's biology, priorities, and daily life.   Health and Human Performance Optimization to Enhance Military Readiness — U.S. Department of War https://media.defense.gov/2026/Jul/15/2003961654/-1/-1/1/HEALTH%20AND%20HUMAN%20PERFORMANCE%20OPTIMIZATION%20TO%20ENHANCE%20MILITARY%20READINESS%20OSD004430-26%20RES%20FINAL.PDF   Influence of CAG Repeat Polymorphism on the Targets of Testosterone Action — Giacomo Tirabassi et al. https://pubmed.ncbi.nlm.nih.gov/26421011/   Comparative Effects of Daily and Weekly Boron Supplementation on Plasma Steroid Hormones and Proinflammatory Cytokines — Mohammad Reza Naghii et al. https://pubmed.ncbi.nlm.nih.gov/21129941/   Women's Health Initiative — National Heart, Lung, and Blood Institute, National Institutes of Health https://www.nhlbi.nih.gov/science/womens-health-initiative-whi   Surviving Sepsis Campaign Adult Guidelines — Society of Critical Care Medicine https://www.sccm.org/survivingsepsiscampaign/guidelines-and-resources/surviving-sepsis-campaign-adult-guidelines   The Longevity Lab — Dr. Jonathan Schoeff and Candace Schoeff https://longevitylabwellness.com/   Jonathan Schoeff on Instagram — Dr. Jonathan Schoeff https://www.instagram.com/jonschoeff/   Jonathan Schoeff on YouTube — Dr. Jonathan Schoeff https://www.youtube.com/@drjonschoeff   Show Notes   00:00 Welcome to the Hart2Heart Podcast 00:42 Military Low T Screening 04:32 Normal Ranges and Treatment 08:19 Free Testosterone and Insulin 12:35 High SHBG and Enclomiphene 15:54 hCG Fertility and Protocols 19:35 Obesity Low T Strategy 23:26 Aromatase Inhibitors and Estrogen 26:51 DHT Mood and Libido Balance 28:57 DHT Balance Risks 30:10 Minimum Effective Dose 31:55 Longevity Strategy Mindset 33:31 Clinic Cuts Alcohol Use 35:40 Goals Drive Strategy 38:06 Body Fat Targets Debate 41:54 Sustainable Leanness 45:33 Personalized Nutrition Plans 48:09 Beyond Body Fat Metrics 52:29 Rules Not Regulations 53:31 Wrap Up And Where To Find   The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart

TRT: La verdad sobre la terapia de reemplazo de testosterona | Serie completa La testosterona es, probablemente, una de las hormonas más incomprendidas y rodeadas de mitos. En esta serie especial de tres episodios, analizamos desde una perspectiva científica qué es realmente la Terapia de Reemplazo de Testosterona (TRT), quiénes pueden beneficiarse de ella y por qué no debe confundirse con el uso de esteroides para mejorar el rendimiento deportivo. Hablamos sobre cómo el cuerpo produce testosterona de forma natural, qué significan los valores medidos en nanogramos por decilitro (ng/dL), cómo un médico diagnostica el hipogonadismo y qué estudios de laboratorio son fundamentales antes de iniciar un tratamiento, incluyendo testosterona total y libre, SHBG, LH, FSH, estradiol, hemoglobina, hematocrito y PSA. También explicamos los diferentes ésteres de testosterona, como el cipionato, el enantato, el propionato y el undecanoato, sus vidas medias, sus ventajas y desventajas, así como las distintas vías de administración: inyecciones intramusculares, subcutáneas, geles, parches e implantes. Finalmente, desmontamos algunos de los mitos más comunes sobre la TRT. ¿Es lo mismo que usar esteroides? ¿Produce infertilidad? ¿Encoge los testículos? ¿Es necesario utilizar hCG o anastrozol? ¿Aumenta el riesgo de cáncer de próstata? ¿Hay que donar sangre obligatoriamente? Respondemos estas y muchas otras preguntas basándonos en la evidencia científica disponible y en las recomendaciones actuales de la medicina. Si eres un hombre mayor de 30 o 40 años, entrenas con regularidad, has escuchado hablar de la TRT o simplemente quieres entender cómo funciona la testosterona en el organismo, esta serie te dará las herramientas necesarias para tomar decisiones informadas y comprender que la salud hormonal va mucho más allá de una simple cifra en un análisis de sangre. Porque cuando se trata de tu salud, la información correcta siempre será tu mejor herramienta. #eliarevalopodcast #vospodes #mycoacheli #gorillazbarbell #MetCon #indianapolis #jcfit #USArmy

Ted's testosterone was almost 200 — 198 to be exact — and he looked healthy on the outside. Muscle, working out, doing the podcast. On the inside his hormone floor was gone. Then he did the work Mark Holman coaches men through, and now he's at 800. No TRT. All natural.   Mark Holman is a mental/physical health and testosterone optimization coach. Creator of the Unchained program (formerly Revival) and the 5-Day High-T Leadership Challenge. He was on the Modern Man Podcast before — this is Round 2. He's since moved his own total T to 1,100, doubled his free testosterone, broke his own income barrier, and met the woman he's now marrying.   In this conversation, Mark and Ted go deep on why "normal" testosterone is a lie (74% of Americans are overweight — that's the population setting the normal range), Mark's named diagnostic concept — the Health Handbrakes — that a standard blood panel won't reveal, why TRT is like winning the lottery (no process, no struggle, and you're on it for life), the free-T-vs-SHBG conversation most doctors skip, the sniper-vs-shotgun reframe for supplements (and the Tongkat Ali standardization rule most brands hide), and the leadership-testosterone connection — why lower T makes you more risk-averse and quietly shrinks your ambition.   Plus: Ted's own before/after receipts (198 → 800 natural), the University of Chicago sleep study that showed a 5-hour night drops testosterone 10-15% in one week, the 2007 JCEM data showing modern men's T is generationally lower than their fathers' generation at the same age, and Mark's closer on the nice-guy generational curse he inherited from his father and broke.   If you're a high-performing man between 25 and 55 with a "normal" blood panel and a feeling something's off — this one's for you.   Key insights from this episode:   Testosterone as an on-demand hormone (not a fixed number) Why "normal T ranges" are a lie (74% of Americans set that baseline) The Health Handbrakes: the root causes of low T that a standard panel misses The Unchained standard: 700 total testosterone is the floor, not the ceiling Free T + SHBG: why total T alone lies to you TRT is like winning the lottery: no process, no struggle, and you're on it for life Sniper vs. Shotgun supplementation (and the Tongkat Ali 2% eurycomanone rule) The testosterone-leadership connection: why low T makes you risk-averse Ted's before/after receipts: 198 to 800 natural in 18 months Mark's N=1 story: 1,100 total T, doubled free T, wife met, business broke through   Chapters: 00:00 The confession — my T was 198 02:04 What's Changed About Testosterone? 04:25 Can You Naturally Increase Testosterone? 05:47 Why "Normal" Blood Work Isn't Enough 08:36 The Testosterone Range Doctors Miss 10:00 Ted's Testosterone: 198 → 800 Naturally 11:57 What to Do If Your Doctor Says You're "Normal" 14:20 Can You Come Off TRT? 15:42 TRT vs. Fixing the Root Cause 17:58 Stress, Sleep & Free Testosterone 20:15 When Is TRT Actually Necessary? 23:04 Why Men's Testosterone Keeps Declining 25:42 The Truth About Testosterone Supplements 29:43 Zinc, Vitamin D & Deficiencies Explained 30:36 Why Most T Boosters Don't Work 33:22 The Hidden Cost of Low Testosterone 36:42 Testosterone, Leadership & Confidence 39:22 Does Sunlight on Your Balls Work? 40:23 Mark's Results: 1,100 Testosterone 45:14 Health, Wealth & Love 45:47 Free Blood Work Analysis 46:47 The Lesson That Changed Mark's Life 49:09 Ted's Biggest Takeaways Connect with Mark Holman: Instagram: https://www.instagram.com/markholmanhealth/ Free Master Class: https://go.markholmanfitness.com/testosteronemasterclass Linktree: https://linktr.ee/Markholmanhealth  

Testosterone, not GLP-1s, is what finally let Chalene Johnson lose body fat and build real muscle after 40, and she's laying out exactly how in this episode. Chalene explains why her total testosterone always looked normal on paper while she still felt exhausted and stuck in the gym, until a clinician finally tested her free testosterone and SHBG (sex hormone binding globulin) and found the real problem. In her words, total testosterone is the money in the bank, free testosterone is the cash in your pocket, and SHBG is the bank teller deciding how much you actually get to spend. She also gets into why she skipped the growth peptides everyone's talking about (tesamorelin, ipamorelin, CJC-1295) and switched from monthly testosterone injections to a daily cream instead. She talks candidly about the mold exposure that wrecked her hormones, caregiving through her father-in-law's Alzheimer's, and why she stopped weighing herself and started tracking body fat with an InBody scale instead. Topics discussed: testosterone for women, free testosterone, total testosterone, SHBG, hormone replacement therapy, perimenopause, GLP-1, tesamorelin, ipamorelin, CJC-1295, HGH, IGF-1, progressive overload, body composition, InBody scale, DEXA scan, mold toxicity, testosterone cream Midi Health testosterone for women: https://chalene.com/test Midi Health hormone and menopause care: https://chalene.com/midi   Go Beyond The Podcast Join Chalene on her private podcast

Chalene Johnson breaks down the Instagram AI feature that had the internet in a panic last week, why deepfake scammers are now stealing real videos and subtly altering someone's voice and appearance to make fake endorsements look real, and what to watch for so you don't get fooled. She also shares a new survey showing that a large percentage of perimenopausal and menopausal women have no idea what stage of reproduction they're in, and explains why she's been getting stronger and leaner using a hormone marker called sex hormone binding globulin, or SHBG, something most doctors won't test unless you specifically request it. She recommends Midi Health for anyone who wants a full hormone panel done right. Chalene gives a quick update on the Blake Lively and Justin Baldoni legal saga, including the ongoing dispute over $8 million in legal fees, then moves into the difference between Botox, Juvederm, and Sculptra, her own experience with Sculptra after her facelift, and a new lawsuit against Juvederm maker AbbVie. She closes with a passionate defense of Madonna following her World Cup halftime performance, walking through Madonna's decades of reinvention, her physical training history, and why Chalene believes the ageism criticism aimed at her is completely out of line. Topics discussed: Instagram, AI deepfakes, perimenopause, menopause, sex hormone binding globulin, Midi Health, Blake Lively, Justin Baldoni, AB 933, Botox, Juvederm, AbbVie, Sculptra, Beauty Broker, Madonna, World Cup Go Beyond The Podcast Join Chalene on her private podcast

Disclaimer: This article is for educational purposes only and is not a substitute for individualized medical advice. Talk to your own physician before making decisions about cancer screening, testing, or treatment.TL;DR* A healthy 58-year-old gets a routine full-body scan, finds a “cancer” that would never have hurt him, and ends up with permanent incontinence from unnecessary treatment. This is more common than most people realize.* Dr. H. Gilbert Welch, a Dartmouth-trained cancer epidemiologist, spent 30 years documenting overdiagnosis — the discovery of cancers that meet the technical definition but would never have caused harm. His estimate: roughly 60% of PSA-detected prostate cancers and 25% of mammography-detected breast cancers fall into this category.* The “5-year survival rate” you hear cited as proof screening saves lives is often distorted by lead-time bias — finding a cancer earlier can make survival numbers look better without adding a single day to anyone's life.* Not all screening is suspect. Colonoscopy, low-dose CT for high-risk smokers, and cervical cancer screening (Pap/HPV) have strong randomized-trial evidence behind them.* The piece conventional screening misses: metabolic health. A 2026 Nature Communications study using machine learning on UK biobank data linked insulin resistance to increased risk across at least 12 cancer types — independent of body weight — and standard checkups rarely test for it.* Want a personalized look at your own metabolic terrain? Book a Metabolic Audit Call — link in show notes, spots limited weekly.The Test That Didn't Save His LifePicture a 58-year-old man. Healthy weight, active, doesn't smoke, feels completely fine. He goes in for a routine total-body scan — the kind now available at imaging centers with no doctor's referral required. Two hours later, a radiologist flags a small spot on his prostate.Six months, two biopsies, and one surgery later, he has a diagnosis: permanent incontinence. And the cancer itself? “Clinically insignificant.” It almost certainly would never have caused him harm. He would have lived out a full life and died of something else entirely, never knowing it was there.The test didn't save his life. It changed it — for the worse.This scenario happens thousands of times a year, and it's exactly what Dr. H. Gilbert Welch — a general internist, cancer epidemiologist, and senior researcher at Brigham and Women's Hospital — spent his career warning about. His book, Should I Be Tested for Cancer?, makes a case that runs against decades of public health messaging: more testing is not automatically better testing, and early detection does not automatically mean lives saved.This article unpacks what Welch got right, where his argument leaves a gap, and what a more complete, proactive approach to cancer risk actually looks like.The Cancer Reservoir: Why Finding More Doesn't Mean Saving MoreFor decades, the operating assumption in medicine has been simple: catch cancer early, save the life. No asterisk, no nuance.Welch's research complicates that. His central idea is the cancer reservoir — the observation that most people carry small clusters of abnormal cells somewhere in their bodies right now. In the prostate, thyroid, breast, or lung. Under a microscope, these cells look like cancer. But many of them will never grow, never spread, and never threaten a life. A person could carry one for thirty years and die at 87 of heart disease, never knowing it existed.The problem is that increasingly sensitive tools — full-body scans, PSA tests, low-dose CT — are very good at finding these dormant clusters. And once something is found and labeled “cancer,” the medical system is built to treat it.Welch's numbers, drawn from randomized trial data, are striking: approximately 60% of PSA-detected prostate cancers are overdiagnosed, meaning they meet the technical definition of cancer but would never have caused symptoms or death. For mammography-detected breast cancers, the estimate is around 25% — meaning roughly one in four women treated for a screen-detected breast cancer may never have needed that treatment: the chemotherapy, the radiation, the surgery, the fear, the financial cost.This isn't an anti-medicine argument. It's a call for a conversation that rarely happens: here's the case for this test, and here's the case against it — here's what we might find that helps you, and here's what we might find that sets off a chain reaction you'll spend years managing. For most patients, that conversation never occurs.The 5-Year Survival Stat Is Misleading YouFive-year survival rates for cancer are often cited as evidence that screening works — and they sound like exactly that. But Welch shows why the number can be deceptive, and it comes down to lead-time bias.Here's the mechanism. Imagine a woman whose cancer will kill her at 65, regardless of when it's found. If screening catches it at 62, she lives three years with the diagnosis before dying at 65 — a five-year survival rate under five years. But if that same cancer isn't found until symptoms appear at 64, she lives one year with the diagnosis and dies at 65 — a five-year survival rate of zero.Same woman. Same cancer. Same date of death. But the version of her found earlier through screening appears, statistically, to have “survived longer.” Screening didn't add a single day to her life — it just moved up the start date of her diagnosis. It's the equivalent of claiming a win in a race because someone moved your starting line 200 meters ahead of everyone else's: you didn't run faster, you just started earlier. The finish line never moved.Now layer in overdiagnosis. If 1,000 people are diagnosed with cancers that would never have hurt them, and all 1,000 are alive five years later — which they would have been regardless — the survival statistics look dramatically better without a single life actually being saved. Welch's research shows that 5-year survival rates can climb while actual cancer death rates stay flat. More survivors on paper. Same number of people dying.None of this means medicine isn't making genuine progress in some cancers — colon cancer being a clear example, discussed below. It does mean that 5-year survival statistics, on their own, are not proof that a screening program is saving lives.Where the Evidence for Screening Is Actually StrongIt would be a mistake to leave this discussion thinking all screening is suspect. Welch himself is careful to draw a distinction, and there are tests with solid, randomized-trial evidence behind them.Colonoscopy for colorectal cancer is arguably the strongest case for screening that exists. It's unique because it doesn't just detect cancer — it can prevent it, by removing precancerous polyps before they ever become malignant. Colon cancer incidence and mortality have both dropped measurably in populations with high screening rates. If you're 45 or older, or have a family history, this is worth a serious conversation with your doctor.Low-dose CT for lung cancer, in high-risk individuals specifically, showed a 15–20% reduction in lung cancer deaths in the National Lung Screening Trial — but only among heavy smokers (roughly a pack a day for 20+ years). The risk-benefit math works because the baseline risk in that population is high.Cervical cancer screening — Pap smears and HPV testing — is a genuine public health success story. Rates have dropped dramatically since routine screening began, because cervical cancer has a long, slow, detectable precancerous stage that can be caught before it turns invasive.The common thread: these screenings either catch a long, slow precancerous process, or they target a population where the risk is already high enough that the math clearly favors testing. That's the question worth bringing to your doctor: given my specific risk factors, does the math on this test work in my favor?By contrast, the evidence is much weaker for consumer-marketed total-body scans, full-body MRI as a general “optimization” tool, universal PSA screening in all men over 50, and mammography in average-risk women in their 40s. These aren't mandates — they're conversations, and informed consent means understanding both sides before deciding.The Harms Nobody Talks AboutHealthcare marketing tends to present testing as one-sided: test early, catch it early, save your life. Welch's research catalogs the costs that rarely make it into that pitch.False positives. A mammogram flags a shadow. It isn't cancer — but you don't know that yet. Six weeks of follow-up imaging, maybe a biopsy, and the stress hormones flooding your body during that stretch are a real physiological cost, even when the final answer is “you're fine.”Unnecessary treatment. When a cancer that would never have caused harm is treated anyway — with surgery, radiation, or chemotherapy — the harm is real and the benefit is zero.The cancer label itself. Research shows that being labeled a cancer patient, even for a cancer that's never actively treated, changes a person's psychology, relationships, insurability, and life trajectory. Welch identifies this as a form of harm medicine rarely accounts for.Radiation exposure. Repeated CT scans carry cumulative radiation risk. A full-body scan can expose a person to the radiation equivalent of hundreds of chest X-rays — a real risk added to the body in pursuit of a cancer that may never develop.Welch's central reframe: the question isn't “should I get tested,” it's “given my risk factors, my age, my family history, and my values, does the math on this specific test work in my favor?” That's informed consent — and most people never get that conversation.The Missing Piece: Your Metabolism Is an Early Warning SystemWelch's work is thorough on what not to do. Where it leaves a gap is the proactive question: if blanket screening of healthy people isn't the answer, what is?The answer lies in the years — sometimes decades — before a tumor ever forms. Cancer doesn't appear overnight. The cellular environment that allows it to take root and grow develops gradually, and it leaves metabolic fingerprints long before any scan could detect a tumor.The clearest evidence for this comes from a 2026 study published in Nature Communications, which used machine learning on a massive UK database and linked insulin resistance to a significantly increased risk of at least 12 types of cancer. Pancreatic cancer risk was elevated by roughly 29%, colon cancer by 18%, and breast cancer by 13% — and critically, this risk showed up independent of body weight. A person at a healthy weight can still be carrying the metabolic dysfunction that drives cancer risk, and a standard annual physical would miss it entirely, because most doctors check fasting glucose, not fasting insulin. By the time glucose is elevated, insulin regulation has often been off for years.Layer in chronic inflammation (measured by hs-CRP), elevated ferritin, low vitamin D, rising homocysteine, and a poor triglyceride-to-HDL ratio, and what emerges is a picture of a metabolic environment that is increasingly hospitable to cancer. Think of it as soil: a healthy garden doesn't grow weeds easily, but depleted, imbalanced soil invites them. Cancer is the weed. Metabolic dysfunction is the depleted soil. The strategy, then, is to work on the soil rather than wait to spot the weed.What to Actually Do About ItPath A: Testing to ask your provider forThese tests build a real metabolic picture — the kind that shows soil quality before any weed appears.* Fasting insulin + HOMA-IR — not just fasting glucose. This is likely the single most important test most doctors aren't ordering.* Hemoglobin A1c — your 3-month blood sugar average.* hs-CRP — a high-sensitivity marker of systemic inflammation.* Full lipid panel, including TG/HDL ratio — a ratio above 3 is a strong metabolic red flag.* Ferritin — elevated levels are increasingly linked to inflammatory cancer environments.* Vitamin D (25-OH) — low levels are associated with higher cancer risk across multiple types; optimal is 60–80 ng/mL, not just “in range.”* Homocysteine — a methylation marker that, when elevated, signals oxidative stress.* LDH (Lactate Dehydrogenase) — rises when cells are under metabolic stress.For a deeper look, consider a comprehensive nutrient and organic acids panel (NutrEval), a gut microbiome panel (GI-MAP) — the gut-cancer connection is real — and a full hormone panel including cortisol, estrogen, testosterone, and SHBG.Path B: Lifestyle changes to start today* Eat in this order: protein and fat first, vegetables second, starches last. This alone can meaningfully blunt post-meal blood sugar spikes.* Cut refined sugars and seed oils — the two most direct dietary drivers of insulin resistance and inflammation.* Move daily. At minimum, 150 minutes of moderate activity per week, resistance training twice a week, and even a 10-minute walk after meals to improve glucose metabolism.* Prioritize sleep. Poor sleep disrupts glucose metabolism after a single bad night. Seven to nine hours is non-negotiable for metabolic health.* Manage stress. Chronic cortisol elevation drives insulin resistance — this is biochemistry, not soft advice.You don't need to do all of this at once. Pick one test to ask for at your next appointment, and one lifestyle change to start this week.Summary & Next StepDr. Welch's research makes an uncomfortable but important case: early detection is not automatically synonymous with lives saved, the 5-year survival statistic can be misleading, and testing healthy people carries real costs — false positives, unnecessary treatment, radiation exposure, and the psychological weight of a cancer label. At the same time, some screenings — colonoscopy, cervical cancer screening, low-dose CT for high-risk smokers — have strong evidence behind them and are worth pursuing for the right person.What's missing from that picture is a proactive strategy, and that's where metabolic health comes in. Insulin resistance, chronic inflammation, and blood sugar dysregulation show up years before cancer does, and unlike a full-body scan, they're both measurable and fixable.If you want a clear picture of where your own metabolic terrain stands — and what your highest-leverage next steps are — book a Metabolic Audit Call. It's a complementary 45-minute session where we review your current labs, symptoms, health history, and goals together. Spots are limited each week; the link is in the show notes.References* Welch, H.G. Should I Be Tested for Cancer? Maybe Not and Here's Why. University of California Press.* National Lung Screening Trial Research Team. Reduced lung-cancer mortality with low-dose computed tomographic screening.* Nature Communications (2026). Machine learning analysis of UK biobank data linking insulin resistance to increased risk across 12 cancer types, independent of body weight.* Thrive 120 Podcast, Episode 126: “Should I Be Tested for Cancer? What Dr. Welch Got Right — And What He Missed,” This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit tripleplaydoc.substack.com/subscribe

In this episode of the Habit Based Lifestyle Podcast, host Jesse Ewell breaks down why the biggest breakthroughs in business, health, marriage, and leadership don't come from more information – they come from your daily habits. Takeaways: From chiropractor to hormone expert: Dr. Mark went from traditional chiropractic and 6 neuropathy clinics to a cash-based hormone and peptide practice serving thousands. Insurance battle became the turning point: A 10‑year fight and a potential $4M clawback (which he ultimately won) pushed him to leave insurance and go all‑cash. "Normal" labs are not optimal: He focuses on free testosterone, SHBG, estradiol, and hematocrit, not just "normal" total T ranges. Low T shows up before libido issues: Brain fog, stubborn belly fat, poor gym results, and non‑restorative sleep are early warning signs. Men need estrogen too: Zeroing out estrogen wrecks recovery, sleep, mood, and erections; balance—not elimination—is the goal. Sub‑Q TRT works better for many: Easier injections, good absorption, and fewer estrogen/hematocrit issues than old-school IM shots. Hormones can change mental health trajectories: Optimizing testosterone has helped some men avoid or later taper psych meds (with their MDs). Peptides & NAD are the next layer: Tools like BPC‑157 + TB‑500, Glow/Clo, Mot‑C, and NAD are used for repair, fat utilization, energy, and anti-aging. You can't out-inject a bad lifestyle: Without protein, movement, sleep, hydration, and collagen, meds and peptides only "rent" results. Massive opportunity for chiropractors: Peptides are a projected $300B market, and patients will get them somewhere—quality sourcing (503A/503B) and real education matter. Content builds authority: Books, podcasts, and social media turned Dr. Mark into a recognized expert—and he urges practitioners to "embrace the suck" and start creating. Perfect for entrepreneurs, small business owners, and anyone looking to scale their business through social media. Click the link below and learn how Jesse and his team can help you achieve similar transformative results. To find out more about the VIP weight loss system email me directly or reach out on socila media. Learn more about Jesse though the following links:   VIP WEIGHT LOSS SYSTEM HBL Lifestyle Secrets Group on Facebook Personal Website HBL Website Instagram Email

Neste episódio do Papo com Profa. Mila Cabral, discutimos os principais pontos do documento publicado em 2026 pela SBEM, SBU e ABEMSS, que padroniza o diagnóstico e o tratamento do hipogonadismo no Brasil. Você vai entender o conceito da doença, as novidades na interpretação dos exames laboratoriais, o papel da testosterona total, SHBG e testosterona livre, as indicações da terapia de reposição hormonal e os riscos do uso indiscriminado de testosterona e anabolizantes. Um episódio baseado em evidências científicas, com foco na prática clínica e laboratorial.

Why does one woman feel incredible on hormone replacement therapy while another gains weight, feels anxious, or sees no improvement at all? The answer isn't simply the hormone—it's how your body processes it. In this episode, Dr. Brendan McCarthy explains why the route of hormone delivery (oral, topical, injectable, or pellets) dramatically changes how hormones behave in the body. He also breaks down the role of liver metabolism, sex hormone-binding globulin (SHBG), body fat, inflammation, insulin resistance, and lab timing—and why these factors matter when creating an individualized hormone treatment plan. You'll learn: Why the same hormone can produce completely different results in different women How oral, topical, injectable, and pellet hormones affect your body differently Why "normal" lab results don't always mean your hormones are optimized The importance of free testosterone vs. total testosterone How inflammation, body fat, and liver function influence hormone metabolism Four questions every woman should ask her hormone provider Why hormone therapy requires ongoing monitoring—not just a prescription Hormone replacement therapy is never just about writing a prescription. It's about understanding what your body does with it.  

Dave Crosland and Scott McNally break down the real differences between Anadrol and Winstrol during a contest cut before answering rapid-fire questions on TRT, Tren, HGH, SHBG, estrogen management, Nandrolone for joint pain, cycle design, bloodwork, CGMs for bodybuilding, and much more. 0:00 Anadrol vs Winstrol (Preview) 0:25 Support Our Sponsors 5:00 Anadrol vs Winstrol in a Contest Cut 8:30 Steroid Cycles Around a Rotation Job 13:50 Can P5P Reduce Tren Side Effects? 15:25 What Causes High SHBG? 19:40 CGMs for Bodybuilding: Worth It? 23:30 DIM & Calcium-D-Glucarate for Estrogen 25:45 When TRT Changes Your Life 27:35 Is a 50-Pound Second Cycle Realistic? 32:30 Painful Pharma Testosterone Injections 33:30 Should You Bulk with Tren? 35:00 Kenalog, Allergies & Muscle Growth 37:10 Managing Low Estrogen on Cycle 38:00 Nandrolone for Joint Pain 40:29 ApoB vs HDL: Which Matters More? 43:15 HGH Raw Supply Update 48:00 Switching from NPP to Tren 49:30 Is TRT Microdosing Dying? 51:20 Keeping Testosterone High Off TRT 54:00 When to Kickstart a Cycle 59:25 Bloodwork Options in Canada 1:02:00 Uncle Dave's Wisdom UK Blood Work Get your Labs done by Dave in the UK : https://evalbloodanalysis.com/home/ Support the Podcast Patreon — Help keep the show growing. Even $5/month makes a difference. https://www.patreon.com/thinkbigbodybuilding Sponsors TRUE NUTRITION — Custom supplements for serious lifters Use code THINK to save https://www.truenutrition.com/THINK STROM SPORTS — Performance supplements trusted by athletes UK: https://tinyurl.com/ydmbfa54 US: https://stromsportsus.com Supplement Source Canada — Top brand supplements with fast shipping http://www.supplementsource.ca Merch Official THINK BIG Merch — Train, represent, support the brand https://think-big.printify.me/products

This is not just a conversation about hormones. It is a conversation about what it means to age as a woman in a culture that is obsessed with youth, terrified of wrinkles, and wildly uncomfortable with female power after 40. In this roundtable episode, I sit down with Dr. Amy Horniman and Elle Russ to talk about the very real physical, emotional, and identity shifts that happen as women move through perimenopause and menopause. We get into everything from early perimenopause symptoms, thyroid issues, SHBG, testosterone, progesterone, estrogen, libido, vaginal dryness, hot flashes, pelvic floor changes, and how all of these things can affect the way women feel in their bodies. But we also go deeper into the emotional side of all of it. What happens when you are no longer getting the same attention? What happens when your face changes, your body changes, and you realize how much of your worth was tied to being seen as young or desirable? We also have a very honest conversation about hormone replacement therapy, why individualized care matters so much, why pellets are not always the answer, and why so many women are still being failed by outdated medical thinking. And from there, we talk about Botox, beauty standards, confidence, sex, self-worth, and why this stage of life can also be one of the most freeing. Because yes, aging is real. But so is wisdom. So is power. So is the version of yourself that finally stops asking for permission. In this episode, we cover: Early perimenopause signs and how differently they can show up for women How thyroid issues and elevated SHBG can affect sex hormones The difference between rhythmic and static hormone dosing Testosterone for women, including libido, muscle, mood, vaginal health, and pelvic floor support Why so many women struggle to get proper hormone support from conventional medicine The pros and cons of pellets versus creams and injections How aging affects confidence, sex drive, self-image, and identity Botox, beauty standards, and the pressure women feel to stay young Why women deserve to age on their own terms without shame How midlife can become a more authentic, confident, and powerful season of life Who this episode is for This episode is for women in perimenopause and menopause who are trying to understand what is happening to their hormones, their bodies, their libido, their confidence, and their sense of self. It is especially for women who are curious about HRT, frustrated by outdated medical advice, or wrestling with how to navigate aging in a way that feels empowering instead of defeating.   Dr. Amie Hornaman "The Thyroid-Fixer", is host to the top-rated podcast in medicine and alternative health: The Thyroid Fixer™, with listeners around the globe. She is the founder of The Institute for Thyroid and Hormone Optimization, an organization with transformational, proven approaches to address thyroid dysfunction and support people in returning to full health. Dr. Amie is also the creator of The Fixxr™ Supplement line with revolutionary, proprietary supplements that are changing the lives of many people. Ultimately, she is a woman on a mission to optimize thyroid patients around the world and give them their lives back. Visit Dr. Amie's website here. Elle is a world-renowned thyroid health expert, master life coach, and a #1 bestselling author with a degree in Philosophy from The University of California at Santa Cruz. She has helped thousands of people worldwide reclaim their health through her book, The Paleo Thyroid Solution, her online courses and find confidence with her book Confidence as Fuck. Elle has been an admired leader in the paleo, primal, ancestral health industry for a decade. Elle coaches people all over the world - helping them achieve goals and dreams and improving their health. She offers online courses and free masterclasses to empower people to become the best version of themselves. Visit Elle's website here.     Sponsors Get 30% off BATCH Gummies. Go to hellobatch.com/HORMONE and use code HORMONE at checkout. Order your LMNT electrolytes today and get a FREE 8 pack of samples! Plus try it risk free, they have a no-questions-asked refund policy – you don't even have to send it back! Get 15% off Masszymes By BiOptimzers products at bioptimizers.com/hormone with coupon code HORMONE.     Are you in perimenopause or postmenopause and struggling with symptoms—but not getting the support you deserve? At Midlife Solutions, we specialize in hormone optimization for women in midlife. Our all-female clinical team offers telehealth care across all 50 U.S. states, with the ability to prescribe bioidentical estrogen, progesterone, testosterone, and thyroid medication.   Book your FREE Hormone Discovery Call Find out what's really driving your symptoms and what your next best steps are.   Visit the website: https://karenmartel.com   Shop the Midlife Solutions Store Over-the-counter bioidentical hormone creams and oils — no prescription needed. Including: • Progesterone • Estrogen Face Cream • Vaginal Moisturizer and more!   Take the Hormone Quiz Discover hidden hormone imbalances that could be driving your symptoms. Get personalized results (and yes, they may surprise you).   Women's Peptide Weight Loss Program Clinically guided, hormone-aware weight loss for midlife women.   Midlife RESET HRT Program A complete, supportive approach to hormone replacement therapy in midlife.   Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert   Karen's Facebook Karen's Instagram

You may be doing everything right, yet your testosterone could still be declining faster than you realize.In this episode, discover why testosterone naturally changes after age 30, how simple morning exercises can help support healthy hormone levels, and which everyday habits may be working against you. Learn when lifestyle changes may no longer be enough and why proper hormone testing matters before starting testosterone therapy. This conversation uncovers practical strategies that could make a real difference in your energy, strength, and overall health.Tune in now to learn how to support your testosterone safely and make informed decisions about your long-term wellness.--------------Key TakeawaysExercise between 7 a.m. and 10 a.m. to naturally support testosterone.Bodyweight squats and hip hinges activate large muscle groups.Poor sleep, stress, and alcohol can lower testosterone.Testosterone naturally declines by 1% to 2% yearly after age 30.Get blood work before starting testosterone therapy.Monitor free testosterone, SHBG, estradiol, and DHT regularly.Testosterone pellets and injections are common treatment options.Safe hormone monitoring helps reduce treatment side effects.--------------Resources mentioned:Modern Man CribMediterranean DietGood Morning Wood SmoothieRenew with Dr. Anne--------------Curious about how you can boost your bedroom game and build lasting confidence? Check out the course at getwoodnow.com and start your journey to feeling like yourself again!--------------If you enjoyed this episode and want to learn more and get more tips, subscribe to The Modern Man newsletter for exclusive content delivered straight to your inbox! https://dranne.co/themodernman--------------Follow Me On:InstagramTwitterFacebookTikTokYouTube--------------For all links and resources mentioned on the show and where to subscribe to the podcast, please visit https://truongrehab.com/increase-testosterone-naturally-after-30--------------Want to regain control of your sex life? It's time to reverse the effects of ED on your life. Join the Modern Man Club and embark on your journey to complete recovery and community.--------------Reveal the FREE treatment most men ignore that solves thousands of erectile dysfunction cases every year, plus the 5 biggest mistakes you must avoid if you want to say goodbye to your ED. Uncover it all in my free eBook, available to download now.https://dranne.co/ebook

Why “Normal” Isn't Always Optimal with Dr. Keith Nichols In Part 1 of this three-part series, Dr. Keith Nichols, Medical Director and CEO of Tier 1 Health & Wellness, deep dives into one of the most misunderstood topics in men's health: testosterone.Dr. Nichols breaks down why testosterone levels have declined over time, how lab reference ranges have shifted, and why many men are told their numbers are “normal” even when they are experiencing symptoms consistent with testosterone deficiency.Dr. Nichols discuss the difference between population-based reference ranges and individual physiology, the importance of free testosterone, the role of SHBG, and why a single lab value should not be the only factor used to determine whether a man is healthy, optimized, or appropriately treated.This episode is about challenging dogma, questioning outdated assumptions, and returning to the evidence.Topics discussed in this episode include:Testosterone levels declining across generationsWhy lab reference ranges have shifted lower over timeThe problem with using one universal testosterone thresholdTotal testosterone vs. free testosteroneHow SHBG affects testosterone availabilityWhy “normal” does not always mean optimalWhy symptoms, history, and clinical context matterThe limitations of current testosterone guidelinesWhy men may be undertreated despite feeling symptomaticThis is Part 1 of a 3-part series: Testosterone: Beliefs vs. Science.Connect with Victory Men's Health:Website: https://www.victorymenshealth.com/Podcast: https://www.victorymenshealth.com/podcastInstagram: https://www.instagram.com/victorymenshealth/Facebook: https://www.facebook.com/victorymenshealthAmy Stuttle Instagram: https://www.instagram.com/amystuttle/Connect with Dr. Keith Nichols and Tier 1 Health & Wellness:Tier 1 Health & Wellness: https://tier1hw.com/Dr. Keith Nichols Bio: https://tier1hw.com/personnel/keith-nichols/Tier 1 YouTube: https://www.youtube.com/tier1healthandwellnessTier 1 Health & Wellness Podcast: https://podcasts.apple.com/us/podcast/tier-1-health-and-wellness-podcast/id1724352005Disclaimer:This podcast is for educational and informational purposes only and is not intended to provide medical advice, diagnosis, or treatment. Listening to this episode does not establish a patient-provider relationship with Amy Stuttle, Victory Men's Health, Dr. Keith Nichols, Tier 1 Health & Wellness, or any guest featured on the podcast.Always consult with your own qualified healthcare provider before starting, stopping, or changing any medication, supplement, hormone therapy, or treatment plan. Individual results may vary, and medical decisions should be made based on your personal health history, symptoms, lab work, risk factors, and an appropriate clinical evaluation.

The Menopause Mastery Show | PMOS Explained: How to Read the Patterns (and What You Have Missed) | Episode 286 Solocast with Dr. Betty Murray

The Menopause Mastery Show | PMOS Explained: How to Read the Patterns (and What You Have Missed) | Episode 286 Solocast with Dr. Betty Murray

The receptor that switches off your appetite on a GLP-1 drug is the same one wired into your reward circuitry, your hormones, and your blood vessels, which means when you turn down hunger, something else may be getting turned down too, and for most people taking these drugs, nobody ever checked.In this solo episode, Dr. Gabrielle Lyon discusses:Why the same drug class can improve sexual function in men with obesity while potentially dampening it in lean or postmenopausal women — and why the deciding factor isn't the drug, it's the bodyHow rapid weight loss raises SHBG, the protein that soaks up free testosterone, so a "normal" total testosterone result can hide a real deficit your bloodwork won't flagWhy women make up 60–70% of GLP-1 prescriptions yet the entire evidence base for female sexual function is two case reports, with zero validated questionnaires in any pivotal trialThe three-tier action plan for anyone on or about to start a GLP-1 — baseline your sexual function first, get free testosterone tested, and protect muscle with protein and resistance trainingWhether you're on a GLP-1 drug or considering one, you'll walk away knowing exactly what to measure before you start and what to watch for after — so a change in your sexual health gets caught as the vital sign it is, instead of being quietly dismissed.Thank you to our sponsors:Cozy Earth - Go to https://bit.ly/44qcXtu for up to 20% off! Lucy - Get 20% off your next order with code DRLYON at https://bit.ly/3QEpYMX or find yours in store at https://bit.ly/3SGAEv3 .Kettle & Fire - Head to https://bit.ly/4oJokGu and use code DRLYON for 25% off sitewide. That is K-E-T-T-L-E and Fire dot com slash DRLYON, code DRLYON for 25% off. Also available at select Sprouts, Whole Foods, and Kroger locations nationwide.Explore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon's clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters00:00 - Introduction01:30 - The 35-year-old patient case04:00 - The question: harm or help?05:00 - The case against: the 4.5x ED study06:30 - FAERS database and 182 reports08:00 - Reward circuits, blood flow, and SHBG11:00 - Women are 70%, the data is two case reports12:30 - The case for: detection bias explained15:00 - Validated studies show testosterone rising17:00 - GLP-1 vs testosterone therapy and fertility19:00 - Same receptor, different body22:00 - Cross-examination: holes in both sides26:00 - Why the drugs may not all be the same30:00 - Confidence levels: what Lyon actually believes33:00 - Tier 1: baseline, hormones, protein, training35:00 - Tier 2 and 3: dose, molecule switch, adjuncts36:30 - Your sexuality is a vital sign If you found this episode valuable, share it with someone who would benefit from it.Disclaimers: This episode includes paid sponsorships. The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Howard and guest hose Sivani Aluru unpack why the new PMOS name matters, how PCOS got tied to “cysts,” and what the evidence actually says about diagnosis, metabolic risk, and treatment. We also challenge a few habits we have all inherited, from pre-op antibiotic dosing to the way we talk about hormones, weight, and fertility with patients. • the evidence gap behind 2 g vs 3 g cefazolin in obese cesarean patients and how practice inertia forms • why PMOS shifts attention toward insulin resistance, metabolic screening, and multidisciplinary care • how NIH, Rotterdam, and androgen excess criteria shape who gets diagnosed and who gets missed • SHBG and free testosterone as a practical way to explain symptoms when total testosterone looks normal • why ovarian follicles are not the same as painful ovarian cysts and why ultrasound can mislead • patient frustration with “just take birth control” and how we explain progesterone protection for the endometrium • lean PMOS, weight-focused bias, and realistic conversations about lifestyle change, GLP-1s, and bariatric surgery • fertility takeaways from PPCOS II, metformin limitations, and what lifestyle trials suggest preconception Be sure to check out thinkingaboutobgyn.com for more information, and be sure to follow us on Instagram.0:00 Welcome And Guest Introduction2:01 The 3-Gram Ancef Habit12:02 PCOS Becomes PMOS12:55 How The Criteria Got Complicated22:00 Insulin Resistance And Free Testosterone30:40 Hormone Panels And TikTok Myths32:30 Ovarian Follicles Are Not “Cysts”36:03 Treating Symptoms Without Dismissing People46:12 Fertility Trials And Lifestyle Results57:27 ACOG At 75 And Why JoinFollow us on Instagram @thinkingaboutobgyn.

In this episode, Dr. Brendan McCarthy breaks down one of the most misunderstood topics in hormone replacement therapy: estradiol. Not all estrogen is the same—and how estradiol is delivered can dramatically affect hormone balance, inflammation, clotting risk, testosterone levels, and overall health outcomes. Dr. McCarthy discusses: • Why route of administration matters (oral, patch, injectable, topical, vaginal, pellet) • How oral estradiol converts to estrone • The differences between estradiol (E2), estrone (E1), and estriol (E3) • Estrone's relationship to inflammation and metabolic health • Oral estrogen and clotting risk • Oral estrogen's effect on SHBG and free testosterone • The impact of oral estrogen on IGF-1 and growth hormone signaling • Why informed consent should be central to hormone therapy • Benefits and limitations of pellets, patches, creams, and injections • Estriol and emerging research in autoimmune conditions such as multiple sclerosis At Protea Medical Center, our philosophy is simple: patients deserve complete information so they can make empowered decisions about their health.

What if the birth control pill you've been told is safe for decades is affecting far more than just pregnancy prevention? In this episode, I sit down with OB-GYN Dr. Johnny Peet for a powerful and nuanced conversation about oral birth control, hormone health, and the risks many women are never fully informed about, especially as they enter their 40s and 50s. We unpack the real differences between oral contraceptives and progesterone-only IUDs, why birth control pills can impact testosterone, mood, sleep, thyroid function, and gut health, and why the conversation around women's health needs to become far more individualized. We also dive into the difficult transition of perimenopause, why so many women feel dismissed or confused during this phase, and the important questions every woman should ask before staying on hormonal birth control long term. Topics We Cover in This Episode:  Why birth control can affect far more than just fertility The hormone shift many women experience in their 30s and 40s What happens when SHBG levels become too high Why perimenopause can feel harder than menopause itself The connection between birth control, gut health, and thyroid function The birth control options Dr. Peet says he would avoid after 40 Why some women feel worse even when their hormone labs “look normal” These conversations matter because women deserve better education, better support, and better options when it comes to their health.  Resources & Links Connect with Dr. Peet Website Instagram Facebook1 Facebook2 YouTube 

Low testosterone isn't just a “male aging” issue — and your thyroid may be playing a much bigger role than you realize. In this episode of Your Thyroid Health, we explore the surprising connection between hypothyroidism and testosterone levels in both men and women.Learn how low thyroid hormone can disrupt key hormones like testosterone, LH, FSH, and SHBG, leading to symptoms like fatigue, weight gain, low libido, depression, brain fog, muscle loss, and sexual dysfunction. We also break down why many symptoms of low testosterone overlap with hypothyroidism — and why so many people are misdiagnosed or overlooked.You'll discover:How hypothyroidism affects testosterone productionWhy thyroid dysfunction can disrupt hormone balanceThe warning signs of low testosteroneWhether treating hypothyroidism can restore testosterone naturallyWhen testosterone replacement therapy may — or may not — help

Broadcast from KSQD, Santa Cruz on 5-14-2026: An emailer from Switzerland follows up on the case of neurological symptoms, warning about the fox tapeworm Echinococcus multilocularis from unwashed garden vegetables and tick-borne encephalitis requiring the FSME vaccine available in Europe. Dr. Dawn adds that cysticercosis from undercooked pork leaves calcified brain lesions detectable on CT scans. Dr. Dawn covers the Andes hantavirus outbreak that sickened at least eleven people on a cruise ship, with the virus spreading person-to-person unlike other hantaviruses. She explains that Andes virus grows to unusually high levels in blood and resists antimicrobial compounds in human saliva, with super-spreaders driving transmission chains. British paratroopers had to parachute medical supplies to an infected passenger on remote Tristan da Cunha island. Dr. Dawn reviews brain health supplements with UCLA longevity expert Gary Small. Both recommend curcumin (500-1,000mg) for anti-inflammatory effects and CoQ10 for statin users. She endorses multivitamins and high-quality fish oil but considers creatine, phosphatidylserine, and nicotinamide riboside insufficiently proven for cognitive enhancement. A caller asks about supplements and testosterone for a 77-year-old. Dr. Dawn recommends topical testosterone (patches, creams, gels) over injections to avoid testicular shrinkage and elevated sex hormone-binding globulin. She emphasizes protein intake matching one's age in grams, branched-chain amino acids during exercise, and warns against fasted training after age 65. An emailer shares news that PCOS is being renamed to polyendocrine metabolic ovarian syndrome (PMOS) because many patients lack ovarian cysts, and genetic males can also have the condition. Dr. Dawn explains it's fundamentally an endocrine and metabolic disorder involving insulin resistance, elevated testosterone, and DHEA dysregulation. A study found that infrasound—low-frequency sound below human hearing range—elevated cortisol and worsened mood in subjects who didn't know and couldn't detect it was playing. Old buildings generate infrasound through aging boilers, ventilation ducts, and metal pipes, potentially explaining why, beyond autosuggestion, that old "haunted" houses feel spooky.

It's time to move beyond the fear-based conversation around testosterone and start discussing the science. Testosterone is not simply a “male hormone.” It plays a critical role in women's physiology — influencing muscle mass, endurance, motivation, cognition, mood, metabolic health, sexual function, recovery, and overall vitality. In this video, I explore: • The evidence behind testosterone and physical performance • Significant improvements in muscle mass and time to exhaustion (running) • Why free testosterone matters more than total testosterone alone • SHBG, albumin binding, and equilibrium dialysis • Genetic differences in androgen receptor sensitivity (CAG repeats) • Why there is no single “optimal” testosterone number for every woman • The importance of individualized dosing and monitoring • Long-term safety data, including transgender testosterone research More than 95% of testosterone is bound to SHBG and albumin. Hormonal physiology is nuanced, individualized, and far more complex than many outdated narratives suggest. The reality is this: When properly prescribed, dosed, and monitored, testosterone therapy is remarkably safe. Referenced studies include: • British Journal of Sports Medicine (May 2020) Effects of moderately increased testosterone concentration on physical performance in young women: a double blind, randomised, placebo controlled study https://drive.google.com/file/d/1z8dvTerB0fnXRhYZ8Y2dwivRHgZKvu_6/view?usp=sharing • Louise Newson pilot study on cognition and mood Effect of transdermal testosterone therapy on mood and cognitive symptoms in peri- and postmenopausal women: a pilot study https://drive.google.com/file/d/1TxdsaiYIzKtsTmSD5NLBazeUeC250Bya/view?usp=sharing • Long-term transgender testosterone safety data Trans men can achieve adequate muscular development through low-dose testosterone therapy: A long-term study on body composition changeshttps://drive.google.com/file/d/1aoDrxl7rMUoHLEIgXI8KAM38pg9W6vhf/view?usp=sharing Bone Safety During the First Ten Years of Gender-Af rming Hormonal Treatment in Transwomen andTransmenhttps://drive.google.com/file/d/1D47vmWxnWr9I_DBMOGcfzakZ8dGNQUMF/view?usp=sharing The efficacy, safety, and outcomes of testosterone useamong transgender men patients: A review of the literaturehttps://drive.google.com/file/d/1M11Qvii1geSYaIr141iedD75IAKV-PAX/view?usp=sharing

No episódio de hoje do Radar Médico, Juliane B. Braziliano, endocrinologista, apresenta os principais pontos do novo posicionamento brasileiro sobre o cuidado de pacientes com hipogonadismo masculino, publicado em conjunto pela SBEM, SBU e ABEMSS.O documento reforça que o diagnóstico do hipogonadismo deve combinar sinais e sintomas clínicos compatíveis com confirmação laboratorial inequívoca de deficiência de testosterona, além de destacar critérios diagnósticos padronizados, investigação etiológica e orientações atualizadas para terapia de reposição hormonal.Tópicos abordados:• Quando investigar deficiência de testosterona• Critérios laboratoriais e interpretação da testosterona total e livre• Diferença entre hipogonadismo primário, secundário e funcional• Papel do LH, FSH, SHBG e exames complementares• Indicações e contraindicações da terapia de reposição hormonal (TRT)• Formulações recomendadas e monitoramento clínico• Obesidade, MOSH e importância das mudanças de estilo de vida

In this episode, we get into more of Q&As that you've emailed to me, posted in the Facebook group, and some directly from my patients. A few more related to HRT, plus we'll cover SHBG, progesterone cycling, and more. These episodes are always my favorite, so be sure to listen in!  For more info on how I can help you, visit my site BetterByDrBrooke.   Resources mentioned in this episode:  Episode #457 - HRT + Joint Pain, Irregular Bleeding, Indigestion & More Episode #450 Tools For Embracing Change, Navigating Choas + Resetting for 2026 Episode #444 - Should You Be Cycling Your HRT?   Grab the Midlife Is More Than HRT guide free right here if, like me, midlife didn't feel quite like you expected. And be sure to listen to episodes #438 and #439, which were all about the mess that midlife can be, and my 3G + 4R process to tackle it!   Stuff I Know You Will Love So many of you take magnesium already but it's often citrate or glycinate only, and while that might be checking a couple of boxes, it might not hit support for muscles and cellular energy. Enter BIOptimizers with 7 forms of magnesium to support sleep, digestion and energy. Try it for  15% off with this link and code DRBROOKE knowing there is a 365, no questions asked, money back guarantee!    Be sure you connect with me in my FREE PRIVATE Facebook group: Hormones & Happiness with Dr. Brooke where other amazing, like-minded women like YOU are already hanging out! Join us!   Follow Dr. Brooke on Instagram and get signed up for my awesome emails here. Seriously, I write really great emails, or so 1000s of women tell me and I'd like to send you one too. To work with Dr. Brooke click here and if you loved this episode, please leave a review!

We are long overdue for an updated conversation on low estrogen — and today I'm pulling it all apart. Estrogen has been villainized for far too long, and I want to change that. This isn't just about reproductive health or getting your period. Estrogen is a master communicator that touches your brain, heart, bones, gut, skin, mood, sleep, libido, and so much more.   In this episode, I cover: Why low estrogen is one of the most missed and underdiagnosed issues for women between 35 and 65 The three types of estrogen (E1, E2, E3) and why estradiol matters so much beyond fertility Why estrogen often increases first in perimenopause before it eventually declines — and what that means for your symptoms The symptom clusters to pay attention to, organized by body system: Brain, mood & sleep — brain fog, anxiety, emotional flatness, rage responses, waking between 2–4am Body composition & metabolic health — belly fat shifts, muscle loss, fatigue, insulin resistance Skin, hair & connective tissue — collagen loss, hair texture changes, joint pain, frozen shoulder, ACL issues Vaginal & urinary health (GSM) — dryness, painful sex, recurring UTIs, urgency, bladder changes Cardiovascular & bone health — rising LDL, heart palpitations, hot flashes, bone density loss Gut & digestion — bloating, constipation, new food sensitivities, the estrobolome and estrogen recirculation The symptoms I personally would never ignore (waking 2–4am, joint pain without a clear cause, rapid body composition shifts, recurrent UTIs, brain fog affecting your work, heart palpitations) What to ask your doctor to test: FSH, LH, estradiol, progesterone, testosterone, full thyroid panel, fasting glucose and insulin, cholesterol, CBC, SHBG — and when functional testing like DUTCH or HTMA may be useful My thoughts on DIM, sulforaphane, calcium-d-glucarate, magnesium, adaptogens (ashwagandha, rhodiola, maca), omega-3s, creatine, collagen, and vitamin D Nutrition strategies — phytoestrogen-rich foods, cruciferous veggies, fiber, protein targets (30–40g per meal), healthy fats, and what to cut Movement priorities — why resistance training 3–4x/week is non-negotiable for bone, muscle, and metabolic health Hormone replacement therapy — what options exist, how to approach the conversation with your provider, and why your protocol will evolve over time   Let's dive in! Thank you for joining us today. If you could rate, review & subscribe, it would mean the world to me! While you're at it, take a screenshot and tag me @jennpike to share on Instagram – I'll re-share that baby out to the community & once a month I'll be doing a draw from those re-shares and send the winner something special! Click here to listen: Apple Podcasts – CLICK HERESpotify – CLICK HERE This episode is sponsored by: withinUs | Use the code JENNPIKE20 at withinus.ca for a limited time to save 20% off your first order and 20% off your first subscription order St. Francis | Go to stfrancisherbfarm.com and save 15% off your all your orders with code JENNPIKE15  Eversio Wellness | Go to eversiowellness.com/discount/jennpike15 and save 15% off every order with code JENNPIKE15 /// not available for "subscribe & save" option Free Resources: Free Perimenopause Support Guide | jennpike.com/perimenopausesupport Free Blood Work Guide | jennpike.com/bloodworkguide The Simplicity Sessions Podcast | jennpike.com/podcast Get 20% on thewalkingpad.com using code "JENNPIKE20" Metabolic Guide | jennpike.com/metabolic-guide Get discounts at happybumco.com using code "JENNPIKE" *code doesn't apply with Black Friday sale* Programs: Ignite: Your 8-Week Body Transformation Program | https://jennpike.com/ignite The Peri & Menopause Project  - Join the Waitlist | jennpike.com/theperimenopauseproject Synced Virtual Fitness Studio | jennpike.com/synced Services: Work With Jenn | https://jennpike.com/work-with-jenn/ Functional Testing | jennpike.com/testing-packages Business Mentorship | The Audacious Woman Mentorship:  jennpike.com/theaudaciouswoman Connect with Jenn: Instagram | @jennpike Facebook | @thesimplicityproject YouTube | Simplicity TV Website | The Simplicity Project Inc. Have a question? Send it over to hello@jennpike.com and I'll do my best to share helpful insights, thoughts and advice.

We break down recovery as the real driver of strength and health, then show how chronic inflammation can quietly block progress even when training looks consistent. We connect daily signals like fatigue and resting heart rate with blood work markers so you can stop guessing and start adjusting with context. • recovery as returning to a physiological baseline across nervous system, hormones, and immune regulation • signs of poor recovery like persistent fatigue, sleep disturbances, stalled performance, elevated resting heart rate • systemic inflammation basics and why chronic inflammation harms tissue repair, hormone signalling, mitochondrial function • blood work markers to discuss with your doctor including CRP, ferritin, SHBG, free testosterone, fasting glucose, liver enzymes, vitamin D, cortisol rhythms • why free testosterone can matter more than total testosterone for performance and wellbeing • how often to test blood work and why baselines in younger years can change interpretation later • sleep as the highest priority recovery tool over cold plunges and saunas • anti-inflammatory nutrition basics including omega-3s, berries, olive oil, whole foods, less ultra-processed food and sugar • training balance with deload weeks and the principle that better is better than more • stress management tools like walks outdoors, breathwork, and optional meditation • gut health as an immune regulator and why testing beats self-diagnosing supplements • using a feedback loop with training logs, blood work, and one change at a time Check the show notes. You can email me. I will share. I have a doctor, Dr. Omar Ashtar, who is in North Austin, but we everything is virtual, so you don't have to as long as you live in Texas, you can work with him. Email:  bgbryan@gmail.comWebsite:  http://bartonguybryan.comInstagram: https://www.instagram.com/bartonguybryanYoutube: https://www.youtube.com/@mindsetforgechannelMy 3 Top Episodes of the first 100: 7 Essentials to Building Muscle after 40 3x Olympic Gold Medalist Brendan Hansen MMA Strength and Conditioning Coach Phil Daru 

Dave Crosland and Scott McNally break down the latest real-world bodybuilding and PED topics, including a massive Chicago steroid bust, GH effects, MENT side effects, retatrutide insights, liver health, and practical cycle strategies. This episode of DNS delivers unfiltered discussion, experience-based advice, and industry insight you won't hear anywhere else. 0:00 Support the Podcast – Shop Our Sponsors Below 1:05 Chicago Steroid & HGH Bust – 400 lbs Seized 2:35 Inside the Steroid Bust – What Really Happened 5:15 Will Trade System Changes Catch More Steroid Imports? 8:00 Are Small Packages at Risk? Customs Crackdown Explained 11:30 Controlled Delivery Stories – How Busts Actually Happen 16:00 Did Dusty Hanshaw Get Ripped Off in the UK? 25:00 China Raw Powder Issues – Latest Updates 26:20 Kickstarting Cycles with Tren Ace – Pros & Risks 30:00 Growth Hormone & Bone Growth Explained 31:30 Retatrutide Non-Responders – What's Going On? 34:30 MENT (Trestolone) & Gyno Risk 37:45 Equipoise (EQ) & Hematocrit – Is It Really That Bad? 41:45 Proviron Benefits – Should You Focus on SHBG? 44:00 Does MENT Aromatize? Breaking It Down 46:00 Cutting Cycle: Test, Mast, EQ, Tren E & GH 50:00 Retatrutide & Dopamine – Lowering Reward Response? 55:00 High AST Levels – Understanding Liver Health in Bodybuilding 56:00 Lost His Job Mid-Cycle – What Now? 59:10 How to Use Sustanon for Bodybuilding & Contest Prep 1:01:30 Best Steroid Cycles for Endurance Athletes 1:02:30 Speaking English with Dave 1:11:45 Why We Are Not on Spotify 1:17:50 Behind the Scenes – Podcast Wrap Up UK Blood Work Get your Labs done by Dave in the UK : https://evalbloodanalysis.com/home/ Support the Podcast Patreon — Help keep the show growing. Even $5/month makes a difference. https://www.patreon.com/thinkbigbodybuilding Sponsors TRUE NUTRITION — Custom supplements for serious lifters Use code THINK to save https://www.truenutrition.com/THINK STROM SPORTS — Performance supplements trusted by athletes UK: https://tinyurl.com/ydmbfa54 US: https://stromsportsus.com Supplement Source Canada — Top brand supplements with fast shipping http://www.supplementsource.ca Merch Official THINK BIG Merch — Train, represent, support the brand https://think-big.printify.me/products Merch Official THINK BIG Merch — Train, represent, support the brand https://think-big.printify.me/products

Gros épisode. Nouvel appartement à Bangkok, installé pour un an, on rentre dans le vif.D'abord, la prise de sang longévité : pourquoi tu dois en faire une, quoi demander à ton médecin (testosterone totale + libre, SHBG, cortisol, thyroïde etc.), et pourquoi "normal" ne veut pas dire "optimal". Mon expérience en France et en Espagne avec des médecins qui te disent que tout va bien alors que c'est moyen.Ensuite, le gros morceau : rester en déficit calorique trop longtemps. Pourquoi "si tu perds pas de poids t'es pas en déficit" c'est un raccourci dangereux. La cascade hormonale (cortisol, testo, GH, thyroïde), la flexibilité métabolique, les mitochondries, et pourquoi la réponse n'est pas de manger encore moins mais de réactiver ton système.Plus : les erreurs classiques en accéléré — s'entraîner sans programme, le même split depuis 5 ans, zéro cardio, zéro mobilité, dormir 5h, le yo-yo, et pourquoi s'entraîner c'est une question de vie ou de mort.

Talking about something you've heard me discuss before on here + reinforcing the importance of getting routine bloodwork done. Topics discussed:What routine bloodwork actually tells us (and what it doesn't)CRP and what inflammation markers can indicateLipid panel breakdown (HDL, LDL, triglycerides) + where ApoB fits in for cardiovascular riskVitamin D and its roles beyond bone healthVitamin B12: why it matters and key considerations for plant-based eatersTSH and a discussion around thyroid function and additional labs to checkHemoglobin A1c and long-term blood sugar controlComprehensive metabolic panel (CMP) + CBCTestosterone (total, free, SHBG) and why looking at all three gives better contextNutrition + lifestyle considerations for each+ so much more in-between. It's a longer episode but I know you'll be able to take a few things away from this one. Where to find me: IG: @lukesmithrdCheck out my website HEREFill out a 1:1 coaching application HERETIA for listening!!

Listen to the full episode Download the full episode on Apple or on your favorite podcast platforms. In this quick hits I sit down with Dr. Gillett, to exam the complex world of women's hormones today. We'll be focusing on androgens like testosterone, DHEA, and dihydrotestosterone, and their profound impact on female health. Dr. Gillett provides insights on the role of binding globulins, hormone replacement therapy, and the interplay between insulin and androgens. We also discuss the challenges of menopausal weight gain, the benefits of GLP-1 medications for weight loss, and practical strategies anyone can use for maintaining lean body mass. In this episode we discuss: How androgens such as testosterone, DHEA, and dihydrotestosterone affect women's well-being. Why sex hormone binding globulin (SHBG) is critical for hormone dynamics and stability. Understanding the impact of thyroid binding globulin and cortisol binding globulin on hormone balance. How hormone replacement therapy (HRT) influences women's bodies, especially regarding androgens. Managing testosterone replacement therapy to avoid virilization symptoms like facial hair and voice changes. The role of DHT blockers in managing androgen-related conditions. How SHBG can be harnessed for overall hormone stability and health benefits. Challenges of menopausal weight gain and how hormonal changes affect body composition. Why integrating proper lifestyle habits is essential alongside GLP-1 medications for effective weight loss. How to maintain lean body mass through hormone therapy and lifestyle changes. How oral contraceptives and other synthetic hormones impact SHBG levels and overall hormone balance. The significance of SHBG levels for individuals on hormone replacement therapy or contraceptives. Exploring different forms of testosterone administration, including subcutaneous and intramuscular injections. How estrogen and progesterone influence testosterone levels through negative feedback inhibition. How poor sleep quality and hormonal changes contribute to menopausal weight gain. The paradoxical effects of hormone replacement therapy on body composition and fat gain. Why high SHBG must be paired with adequate hormone levels to avoid feeling unwell. Discussing the challenges faced when SHBG levels are artificially high due to medication. Kyle Gillett https://gilletthealth.com/     Sponsors Get 50% off the Energy Reboot Program hackmyage.com use coupon code HORMONES50.     Are you in perimenopause or postmenopause and struggling with symptoms—but not getting the support you deserve? At Midlife Solutions, we specialize in hormone optimization for women in midlife. Our all-female clinical team offers telehealth care across all 50 U.S. states, with the ability to prescribe bioidentical estrogen, progesterone, testosterone, and thyroid medication.   Book your FREE Hormone Discovery Call Find out what's really driving your symptoms and what your next best steps are.   Visit the website: https://karenmartel.com   Shop the Midlife Solutions Store Over-the-counter bioidentical hormone creams and oils — no prescription needed. Including: • Progesterone • Estrogen Face Cream • Vaginal Moisturizer and more!   Take the Hormone Quiz Discover hidden hormone imbalances that could be driving your symptoms. Get personalized results (and yes, they may surprise you).   Women's Peptide Weight Loss Program Clinically guided, hormone-aware weight loss for midlife women.   Midlife RESET HRT Program A complete, supportive approach to hormone replacement therapy in midlife.   Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert   Karen's Facebook Karen's Instagram

In this episode, Luke sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to unpack the truth about testosterone. They explore the science, debunk common myths, and discuss innovative solutions designed to make hormone therapy more accessible and scalable. From lifestyle factors lowering testosterone levels to the growing importance of female hormone health, this conversation separates evidence from online noise and empowers listeners to take control of their health. What We Cover • The real impact of low testosterone in men and women• Why free testosterone and SHBG testing matters• Myths vs facts around testosterone therapy and steroids• Environmental factors, stress, and microplastics affecting hormones• The shift from injections to oral testosterone solutions• How to legally and safely access therapy• Practical first steps to optimize hormone health Resources Mentioned KYZATREX Oral Testosterone Capsuleshttps://www.kyzatrex.com/ The Testosterone Projecthttps://testosteroneproject.com/ Marius Pharmaceuticalshttps://mariuspharma.com/ Book Reference:Testosterone: Action, Deficiency, Substitution by Eberhard Nieschlag and Hermann M. Behre Connect with Shalin Shah Instagram: https://www.instagram.com/themetabolicceo/Website: https://mariuspharma.com/team/shalin-y-shah/ Disclaimer:This episode is for educational purposes only and is not medical advice. Always consult a qualified healthcare professional before beginning any hormone therapy or medical treatment. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Thank you for joining us for our 2nd Cabral HouseCall of the weekend!   I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks…   Sonja: Dr Cabral thank you so much for all of the wonderful education you have been sharing with us over the years to help us be healthier. My family and I greatly appreciate it along with so many others around the world! I am a 60 year old woman who was diagnosed with hemochromatosis about 2 and 1/2 years ago. Thanks to the minerals and metals test that I completed which raised a red flag on the iron level, I was able to get my doctor to do a ferritin blood test to find out that my level was at 725! Over the past couple of years, I have been working with a hematologist and getting therapeutic phlebotomies as needed. I eat clean, workout and have an overall healthy lifestyle with minimal alcohol consumption. I do a 7-Day Detox 3 to 4 times a year, daily DNS shake along with multiple Equilife supplements. My question to you is - if I was your aunt what protocols or recommendations would you have for me? I would love to reverse the diagnosis of hemochromatosis. In addition, what would be the ferritin range that you would recommend? My hematologist wants it as low as possible (around 30) however my energy is very low when it's at the levels that he desires. Thank you so much for everything that you do. Sonja      Peter: Hi Dr. Cabral, Thanks for the great work you do and your books! I'm generally in good health and currently not on any medications. For the past 2–3 years I've been very consistent with lifestyle habits: clean diet, training 5–6x/week (3x strength, 2x cardio, 1x HIIT), no alcohol, consistent sleep schedule, sauna ~3x/week, and daily bowel movements. Despite this, I've experienced low libido for several years. It fluctuates, but I haven't been able to identify clear triggers or improvements. A few years ago, blood work showed elevated prolactin. My doctor prescribed Dostinex (dopamine agonist), which resolved libido symptoms effectively, but felt too strong. I'd prefer to identify and address the underlying cause rather than suppress symptoms. Recent blood work again shows elevated prolactin and elevated SHBG. Free testosterone is low. Blood sugar is within range but not optimal given my lifestyle. LDL is also elevated. Primary symptoms • Low libido (low initial drive, rare or absent morning erections) • Skin issues for ~1.5 years (none prior): – Redness on chin and temples, flaring after meals and after B-complex supplements – Small forehead bumps resembling acne that appear and disappear within a day Secondary symptoms • Slightly flat mood • Low muscle gain relative to training effort • Occasional cold hands • Frequent urination (including at night) • Low evening energy • Reduced interest in socializing I've tried various supplements over time but without a clear framework or plan. I'm hoping you could share your thoughts on possible root causes and what testing or protocol you would prioritize. Thank you for your work and guidance! Best, Peter     Michelle: Hi Stephen, I've experienced sensitivity to Equilife's Florafilm & another brand of proteolytic enzymes (nausea & vomiting). I have no allergies and have never experienced a negative reaction to a supplement. I am in overall good health and not on any medication and was wondering what might be causing such a reaction? I tried taking just one of the capsules instead of two on an empty stomach and experienced similar side effects. Is this product by chance enteric coated? I read that could help prevent side effects. Lastly is there a product you could recommend in its place to help remove biofilms so that the Para Support protocol will continue to be most effective? I found a product that contains Bismuth Subnitrate, Alpha lipoic Acid and Black Cumin (Priority One Biolm). Would it be ok to take this product in place of the Florafilm? I have been taking just one capsule of it with no side effects (product recommends 2 capsules 4 days a week) or is there a better solution as I do want to do some other Equilife protocols and noticed they also contain the Florafilm product. I love your Podcast and Equilife products and disappointed this one doesn't work for me. Thank you for all you do!      Larissa: Hello Dr Cabral. My 4yrs old son is allergic to dogs, I suspect the saliva. When he pets a dog nothing happens but when a dog licks him or his hands and he touches his face, that area gets red and swollen within minutes. Is this common? Is it possible this will go away? Is there a way to test him for this and more importantly treat him for this? I've heard of the NAET protocol, do you recommend this? Appreciate any advice!         Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3656 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? 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Watch Here : https://www.youtube.com/watch?v=iWP047x7w2g Website: https://vigoroussteve.com/ Consultations: https://vigoroussteve.com/consultations/ eBooks: https://vigoroussteve.com/shop/ YouTube Channel: http://www.youtube.com/user/VigorousSteve/ Workout Clips Channel: https://www.youtube.com/channel/UCWi2zZJwmQ6Mqg92FW2JbiA Instagram: https://instagram.com/vigoroussteve/ TikTok: https://www.tiktok.com/@vigoroussteve Reddit: https://www.reddit.com/r/VigorousSteve/ PodBean: https://vigoroussteve.podbean.com/ Spotify: https://open.spotify.com/show/2wR0XWY00qLq9K7tlvJ000 Patreon: https://www.patreon.com/vigoroussteve

Acne and hair shedding after stopping birth control can feel alarming—but they're often signs that your hormones are waking up and asking for support. In this episode of Cycle Wisdom, Dr. Monica Minjeur explains why post-pill acne and hair loss happen, how long it typically lasts, and when testing actually helps (and when it doesn't). Through Allie's story, you'll learn how SHBG, testosterone, progesterone, nutrients, and ovulation recovery intersect—and what truly helps your skin, hair, and cycles rebalance without panic or unnecessary medications.If post-pill symptoms are leaving you confused or discouraged, you don't have to navigate this transition alone. At Radiant Clinic, we specialize in cycle-informed, restorative care that supports hormone recovery without masking symptoms. Schedule a free discovery call at radiantclinic.com to learn how we personalize care for skin, hair, and fertility health.

In this solo episode of The Eric Bach Show, Eric breaks down what your bloodwork really says about your hormones, health, and performance — and why most guys are leaving massive gains on the table by ignoring it.Whether you're feeling tired, holding onto stubborn fat, or just not performing the way you used to, this is the wake-up call and action plan you didn't know you needed.What you'll learn:– Why “normal” testosterone doesn't mean optimal — and the red flags to look for even if your doctor says you're fine.– What it actually means when your SHBG is low, AST is high, and your free T is in the tank.– Why your liver could be quietly sabotaging your hormones and how to fix it without overhauling your entire life.– The real effects of alcohol on testosterone, liver enzymes, and recovery… even if you're just “a weekend drinker.”– How to spot early signs of burnout, low T, or metabolic slowdown before they become full-blown health issues.– Why some guys thrive into their 40s and 50s while others fall off in their 30s — and the bloodwork markers that predict it.– What most men get wrong about TRT, and how to know if you're a candidate or just missing the basics.– Why you can't out-train hormone dysfunction — and how to build muscle, drop fat, and feel better by fixing what's under the hood.– The importance of a lifestyle-first approach — and how to stack habits that make high performance automatic.– A no-BS look at supplementation: what works, what's a waste, and where to start.Want the full breakdown? Download our Free Testosterone Optimization Guide to get the exact strategies we use to help men raise testosterone naturally, get leaner, and perform better without gimmicks or guesswork.Who this episode is for:– Men in their late 20s to 40s who feel like their edge is slipping — physically, mentally, or hormonally.– Guys who've trained hard but aren't seeing the same results and want to know why.– Anyone who's tired of spinning their wheels and wants a real plan — grounded in data, lifestyle, and results.Work with Eric:Want a custom coaching plan based on your goals, schedule, and bloodwork? Apply for coaching at: bachperformance.com/coaching

‣ Book Your COMPLEMENTARY CONSULATION and CALORIE CALCULATION call:- how much & what to eat

‣ Book Your COMPLEMENTARY CONSULATION and CALORIE CALCULATION call:- how much & what to eat

Dr. Kyle Gillett joins Dr. Erin to break down the physiology behind testosterone regulation, including how SHBG, free versus total testosterone, and androgen receptor sensitivity influence symptoms, metabolic health, and treatment decisions. They discuss why men with similar lab values can feel very different, how lifestyle and insulin resistance affect hormone metabolism, and when tools like TRT or aromatase inhibitors are actually warranted. This episode focuses on practical, evidence-based mechanisms that help patients and clinicians make informed choices about hormone optimization

If your labs are “normal” but you still feel like crap—bloated, fatigued, moody, low libido—this episode is a must-listen. Liz and Becca break down Sex Hormone Binding Globulin (SHBG), the liver-made protein that can block your sex hormones from doing their job. Learn how SHBG messes with testosterone, estrogen, and metabolism… and why your OB/GYN probably isn't testing for it. From reverse dieting and boron to liver health and insulin resistance, we cover exactly what to do when SHBG is high or low. Functional healing starts here.

Most men are told erectile dysfunction is about age or hormones — but that's not the truth. In this episode, Ben Azadi reveals the real root causes of ED and how to naturally restore performance, confidence, and vitality without pills or surgery. You'll learn how lifestyle factors, toxins, mouth breathing, and even mouthwash can impact nitric oxide and blood flow — and how to fix it. Ben shares the 5 hidden causes of erectile dysfunction and a step-by-step blueprint to reverse it naturally through diet, movement, fasting, red light therapy, and simple daily habits. Plus, discover the best supplements, at-home tools, and free resources to boost testosterone, improve circulation, and reclaim your metabolic freedom.

Get access to more than 70 Ask Me Anything episodes with Dr. Rhonda Patrick when you sign up as a FoundMyFitness Premium Member When testosterone runs low, libido isn't the only casualty—muscle mass drops, fat accumulates, insulin resistance rises, and motivation declines. In this episode, Derek from More Plates More Dates highlights common pitfalls that suppress testosterone and evaluates popular testosterone-boosting supplements like Tongkat Ali, boron, and ashwagandha, clarifying what's evidence-based versus overhyped. He also details practical strategies for testosterone replacement therapy (TRT), covering optimal delivery methods, benefits, risks, fertility implications, and key biomarkers to monitor. Timestamps: (00:00) Introduction (04:50) Why is testosterone essential for men? (07:11) The role of testosterone in women's health (08:53) Does higher testosterone shorten lifespan? (12:12) What the castrati reveal about testosterone and longevity (15:07) Free vs. total testosterone—what's the difference? (18:42) Best practices for measuring and interpreting testosterone levels (21:29) Reference ranges or symptoms—which matters more? (24:50) When is high testosterone a red flag? (26:32) What LH and FSH reveal about testosterone production (31:11) Could high SHBG levels be limiting your testosterone? (35:02) Why SHBG increases with age—and how diet and lifestyle accelerate it (39:45) Key symptoms of low testosterone in men (42:46) Is alcohol sabotaging your testosterone levels? (45:39) Why low-fat and low-carb diets might lower testosterone (46:18) Common micronutrient mistakes hurting hormone levels (48:12) How excess body fat impacts testosterone (51:39) When endurance training goes too far (56:02) Are endocrine disruptors truly harming male hormones? (58:42) Debunking myths about declining testosterone in men (1:01:32) Why dietary fat is essential for hormone health (1:03:55) Is a ketogenic diet bad for testosterone? (1:05:10) Which type of exercise boosts testosterone most? (1:07:16) Do vitamin D, zinc, and magnesium actually help? (1:11:36) Does boron significantly raise free testosterone? (1:12:45) Ashwagandha's true potential for testosterone enhancement (1:17:00) Is Tongkat Ali the best herbal testosterone booster? (1:20:51) Tongkat Ali or boron—which is superior? (1:22:20) Shilajit, Tribulus, Fenugreek—do they actually work? (1:23:33) The four best supplements to raise testosterone levels (1:25:17) Dutch test vs. blood test—which is better for cortisol? (1:26:32) When should you consider testosterone replacement therapy (TRT)? (1:34:23) What realistic benefits can TRT provide? (1:37:34) Does TRT raise heart disease and erythrocytosis risk? (1:47:23) Creams vs. injections (1:48:47) Does TRT increase prostate cancer risk? (1:51:01) Hair loss, acne, sleep apnea—what are TRT's real side effects? (1:53:41) The rollercoaster effect of testosterone injections (1:56:15) Could low testosterone be riskier than TRT? (1:59:38) Choosing the right TRT delivery method (2:06:16) Do smaller, more frequent injections reduce risks? (2:08:12) Can you maintain fertility while on TRT? (2:16:12) Why TRT quickly shrinks testicles (2:17:40) Key biomarkers you must track on TRT (2:26:57) Testosterone therapy for women—symptoms, ranges, and risks (2:36:49) Can DHEA supplements safely raise testosterone in women? (2:39:47) What actually causes hair loss? (2:46:00) Does your maternal grandfather determine your hairline? (2:46:48) Why stopping hair loss means accepting risks (2:55:54) How effective are ketoconazole, minoxidil, and microneedling? (2:58:55) Topical vs. oral minoxidil—how do side effects compare? (3:02:00) Is microneedling effective without minoxidil? (3:04:51) Do finasteride and dutasteride alter brain chemistry? (3:06:03) Finasteride and the nocebo effect—are side effects imagined? (3:07:37) Does minoxidil delay baldness or just mask it? (3:09:06) Can dutasteride extend your lifespan? Show notes, transcript, and summary are available by clicking here Watch this episode on YouTube