To Health With That! MTHFR Mutations.

In the last episode, we talked about CBD as a methylation adaptogen, but we haven' talked too much about that term so let's dive in. We know that everyday methylation is important for people with the MTHFR gene or with any methylation dysfunction, but it turns out that long-term methylation care is important too and this can be achieved by getting methylation adaptogens.Methylation adaptogens are substances that help to regulate the amount your genes are methylated. Remember that when genes are methyalted, they are turned off and when they are unmethylated they are turned on. So having stretches of your genome that are undermethylated means the genes in there are allowed to function out of control, and that could lead to bigger problems like cancer.Methylating your genes appropriately is one of the long-term ways to prevent disease and even benefit your children, because research has shown that the way you methylate your genes might pass to your children. Not just the genes themselves, but the methylation tags.The most researched compounds that have been called methylation adaptogens come from food sources - things like caffeic acid from coffee and cruciferous veggies, lycopene from tomatoes and watermelon, resveratrol from red wine. Thanks so much for watching! I have so many other resources for you. Check out the website first for lots of FREE stuff:WEBSITE: https://tohealthwiththat.com/ GENETIC ROCKSTARS (an MTHFR, methylation, and genetics community): community.tohealthwiththat.comAFFILIATE LINKS: Thanks so much for using these links to buy the products you would buy anyway. This allows me to keep putting information out there at no cost to you. You're the best!SEEKING HEALTH (methylation and histamine support supplements - ships internationally): https://bit.ly/3afXYH4STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwtQUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more

Pot is the third most used drug in North America after alcohol and tobacco, so questions about Cannabis and MTHFR are important to ask. The answers, of course, are mixed with some serious pitfalls and also some surprising benefits of CBD for people with MTHFR gene mutations.Nothing is ever fully good or fully bad, and marijuana for MTHFR is the same. When you have an MTHFR gene variant, it is important to know your own risks to make an educated decision about what you want to put in your body. Medical marijuana is widely available and can come in various strengths of THC and CBD, which will affect people with the MTHFR gene mutation in different ways.With MTHFR we do have a different risk profile than average, so educate yourself, advocate for yourself, and be careful about what you put in your body.Thanks so much for watching! I have so many other resources for you. Check out the website first for lots of FREE stuff:WEBSITE: https://tohealthwiththat.com/ GENETIC ROCKSTARS (an MTHFR, methylation, and genetics community): community.tohealthwiththat.comAFFILIATE LINKS: Thanks so much for using these links to buy the products you would buy anyway. This allows me to keep putting information out there at no cost to you. You're the best!SEEKING HEALTH (methylation and histamine support supplements - ships internationally): https://bit.ly/3afXYH4STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwtQUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more

Methylation imbalance and the causative factors leading to methylation imbalance, like the MTHFR gene mutation, show themselves in four distinct personality types. These methylation personality types, methylation archetypes, or MTHFR personalities are called The Achiever, The Athlete, The Activist, and The Artist.The Activist and The Artist are very closely linked. Neither are terribly ambitious or driven, except in the thing that matters to them, whether it's their art, their job (which might not be art or activism), or the cause that matters to them. Both tend to have fewer allergic-type reactions but are more likely to have food sensitivities or chemical sensitivities. Things like wheat sensitivity, soy sensitivity, rashes with the wrong laundry detergent, or headaches after smelling perfume. Both of these personalities thrive on leftovers and fermented foods, even though leftovers and fermented foods are high in histamine.These two personality types also tend to react predictably to supplements, nutrients, and even pharmaceutical drugs. Anything that boosts serotonin, so SSRI medications, St. John's Wort, and melatonin aren't great for these groups. Likewise, the major methyl donors like SAMe, TMG, and DMG are typically not well tolerated by the artist and the activist. Conversely, these groups usually do very well with good sources of folate, like L-5MTHF, food-sourced folate, or folinic acid. Like all people with methylation imbalance, folic acid should not be taken because it can make methylation imbalances worse. Also, the benzodiazepine class of pharmaceuticals is usually well tolerated (although your doctor knows the best choice of pharmaceuticals for you, and your doctor's information is always more informed and correct for you than ours.)Thanks so much for watching today! If you haven't yet discovered your methylation archetype or methylation personality, take the quiz for free now at tohealthwiththat.comAlso, if you're a crappy methylator, MTHFR mutant, or have chronic health issues and you can't figure out why, then check out our online health community. Community.tohealthwiththat.comIf you wish to support this channel by using affiliate links when you buy supplements and self-care that you want to buy anyway, I would appreciate it!Seeking Health: https://bit.ly/3afXYH4Amazon: https://www.amazon.com/s?k=Health+best+sellers&i=stripbooks&camp=1789&creative=9325&linkCode=ur2&linkId=29fff6e3ea954499d2eed32d46428454&tag=tohealthwitht-20Fullscript (for other supplements): https://us.fullscript.com/welcome/thwtQueen of The Thrones Castor Oil Packs: https://shop.queenofthethrones.com/amy-tohealthwiththatFor 10% off any order of $59 or more, use the code AMY_TOHEALTHWITHTHAT10

,Methylation imbalance and the causative factors leading to methylation imbalance, like the MTHFR gene mutation, shows itself in four distinct personality types. These methylation personality types, methylation archetypes or MTHFR personalities are called The Achiever, The Athlete, The Activist, and The Artist.The Achiever and The Athlete are very closely linked. Both are extremely ambitious, perfectionistic, competitive, and driven. Both tend to have more allergic-type reactions to the world. Things like hay fever, hives, dermatographia, and skin flushing with a workout. Neither of these personalities tend to tolerate leftovers very well (because leftovers are also high in histamine).These two personality types also tend to react predictably to supplements, nutrients, and even pharmaceutical drugs. Anything that boosts serotonin, so SSRI medications, St. John's Wort, and melatonin do well for these groups. Likewise, the major methyl donors tend to do well. These are SAMe, TMG, and DMG. Conversely, these groups don't do as well with folate, even the MTHFR-safe forms like L-5MTHF or folinic acid. Also, the benzodiazepine class of pharmaceuticals isn't usually the best choice (although your doctor knows the best choice of pharmaceuticals for you, and your doctor's information is always more informed and correct for you than ours.)Thanks so much for watching today! If you haven't yet discovered your methylation archetype or methylation personally, take the quiz now at tohealthwiththat.comAlso, if you're a crappy methylator, MTHFR mutant, or have chronic health issues and you can't figure out why, then check out our online health community. Community.tohealthwiththat.comPlease support this channel by using affiliate links when you buy supplements and self-care that you wanted to buy anyway (I really appreciate it!):Seeking Health: https://bit.ly/3afXYH4Amazon: HereFullscript (for other supplements): https://us.fullscript.com/welcome/thwtQueen of The Thrones Castor Oil Packs: https://shop.queenofthethrones.com/amy-tohealthwiththatFor 10% off any order of $59 or more, use the code AMY_TOHEALTHWITHTHAT10

Methylation imbalance, often caused by the MTHFR gene mutation, by folic acid excess, or by nutritional deficiencies, shows itself in several personality traits. Some personality traits are common to people with methylation dysfunction, like perfectionism, OCD-tendencies, anxiety, hyper-focus or hypo-focus, and others. These common traits emerge in each methylation archetype pattern in slightly different ways, and by using your personality to determine your methylation archetype, you can benefit by getting general guidelines about supplements and even prescription medications that might work for you. GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://to-health-with-that.teachable.com/p/mthfr-basics WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (metylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more

I have used the terms over methylator and undermethylation in the past to help categorize people to streamline their supplement start with MTHFR or other methylation imbalance, but the terms themselves can be confusing and misleading because they imply a biochemical state that isn't actually there. Logically, it makes sense that an undermethylator would be globally undermethylating things, but that doesn't bear out in reality, and part of that is because these terms (over- and under-methylator) were coined well before we had as much knowledge about the actual biochemistry and genetics linked to it as we do now. Categorizing people in this way does still have some uesful aspects because many of the traits we see in people with methylation imbalance that are used to determine over and under-methylators, still point to some predictable medication reactions, supplement guidelines and other useful information. So how do we keep the good without keeping the names? Tune in next episode because we'll be talking about a new way of looking at this. Methylation Archetypes. GENETIC ROCKSTARS (an MTHFR community): https://community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://to-health-with-that.teachable.com/p/mthfr-basics GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (metylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more

She breaks down the considerations for symptom management and potential risks, particularly regarding tumors and blood labs. In this episode of 'To Health With That,' naturopathic doctor Amy Neuzil discusses the complexities surrounding methylfolate dosing for individuals with MTHFR. High doses of methylfolate could come with some of the same risks as high-dose folic acid, so it's essential to find the right dose for you without overdoing it. The three factors to consider are symptom management, potential risks, and serum folate levels. She breaks down the considerations for symptom management, potential risks, particularly regarding tumors, and blood labs. Amy also shares her own methylfolate regime and emphasizes the importance of personalized care and listening to one's body. 00:00 Introduction 00:31 Introduction to Folate Toxicity 01:25 Considerations for Methylfolate Dosing 01:56 Symptom Management 02:27 Risks of High Folate Doses 02:42 Blood Testing Guidelines 03:40 Personal Methylfolate Regime 05:34 Importance of Personalized Care

Folate is a great thing - it's vitamin B9 and your body needs it to make new cells, replicate DNA, and so much more. But there are risks of too much folate, so how much folic acid is too much? And how dangerous is it to take high dose folic acid over time? The research exists for high dose folic acid, but what about L-5MTHF, or methyl folate? Does high dose methyl folate have the same risks as high dose folic acid? We have so many questions, and very few definitive answers, but there is lots of information that we do have. This episode of the To Health With That! podcast will cover the risks of high dose folic acid, the risks of high dose methyl folate, the risks of high dose L-5MTHF, and what we do and don't know from the research. Thanks for watching! Here are some other links that you might like. Genetic Rockstars - a community for people making the most of their favorite genes and getting better together (first month free for YouTubers!): https://community.tohealthwiththat.com/plans/204575?bundle_token=4da8ed9c5f00a92363bcd15ad2ac26dd&utm_source=manual FREE MTHFR Basics course: https://courses.tohealthwiththat.com/p/mthfr-basics I would appreciate it so much if you would support this channel by using affiliate links when you buy supplements and resources (I heart you!): Seeking Health:  https://bit.ly/3afXYH4 Amazon: https://www.amazon.com/s?k=Health+best+sellers&i=stripbooks&camp=1789&creative=9325&linkCode=ur2&linkId=29fff6e3ea954499d2eed32d46428454&tag=tohealthwitht-20 Queen of The Thrones Castor Oil Packs:  https://shop.queenofthethrones.com/amy-tohealthwiththat  For 10% off any order of $59 or more, use the code AMY_TOHEALTHWITHTHAT10

That's right - season 4 of the To Health With That podcast is finished, so let's talk about what you should be doing this summer (having fun), what I should be doing in the fall (writing), and what kind of episodes you can expect. I'd like to call it To Health With That! Season One BONUS Episodes. Thanks so much for being here and adding so much in terms of comments and questions - I couldn't do this without you. In September we'll have occasional episodes about methylation and MTHFR, maximum safe doses of methyl folate, methylation adaptogens, and a few other big topics that come up. Agent? Editor? Just have a comment? Email me! amy @ tohealthwiththat.com In the season four finale of the 'To Health With That' podcast, host Dr. Amy Neuzil wraps up the season which focused on fatigue - discussing its causes and solutions. She announces a summer break for listeners to enjoy, expressing gratitude for their engagement and inviting them to stay in touch. Amy reveals plans for a reduced schedule next season due to her focus on writing a book, with occasional bonus episodes centered on MTHFR and methylation. Amy also expresses interest in connecting with agents and publishers for her book project and promises updates in the future. The podcast will return with irregular episodes and content mainly focused on MTHFR and methylation topics. 00:00 - Intro 00:35 - Season Four Wrap-Up and Summer Plans 01:09 - A Heartfelt Thank You and How to Stay in Touch 01:32 - Looking Ahead: Season One Bonus Episodes and Book Plans 02:40 - Signing Off: See You After the Break! GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://to-health-with-that.teachable.com/p/mthfr-basics GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (metylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more

Gentle MTHFR Detox Protocol A gentle six-week detoxification protocol tailored for individuals with MTHFR polymorphism. She explains how decreased methylation in MTHFR polymorphism sufferers leads to toxin accumulation and stresses the importance of detoxification. The protocol includes preparatory steps, recommended supplements like NAC and liposomal glutathione, dietary adjustments, and lifestyle changes aimed at supporting the body's detox process. Additionally, she discusses the health benefits of detoxification, such as weight loss and improved sleep, and provides practical tips for easing into detox. The episode also addresses potential detox symptoms and the importance of consulting with a practitioner before starting the protocol. Here's the protocol in written form so you don't have to take notes: https://www.tohealthwiththat.com/gentle-six-week-detoxification-protocol-for-mthfr/ Here's more about castor oil packs: https://www.tohealthwiththat.com/castor-oil-for-mthfr/ GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://to-health-with-that.teachable.com/p/mthfr-basics GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (metylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more 00:00 - Intro 00:30 - Why do a detox 02:07 - Detox Essentials: What You'll Need 03:45 - Pre-Detox Preparation: Weeks 1 and 2 07:02 - The Active Detox Phase: Weeks 3 to 6 10:21 - Closing Thoughts and Community Invitation --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

In Season 4, Episode 21 of the To Health With That podcast, naturopathic doctor Amy Neuzil discusses strategies to combat fatigue by focusing on adrenal health. The episode covers the concept of adrenal fatigue, identifying it in various phases, and introduces a holistic approach to healing the adrenals, emphasizing the role of supplements such as Vitamin C, Magnesium, B Vitamins, and melatonin, along with a special focus on adaptogens like Siberian ginseng, ashwagandha, and holy basil. Neuzil stresses the importance of incorporating these supplements alongside necessary lifestyle changes to prevent the eventual collapse of adrenal health. Additionally, fat-soluble antioxidants are highlighted as beneficial for individuals experiencing adrenal fatigue. The episode serves as a comprehensive guide to understanding and managing adrenal fatigue, but Neuzil reminds listeners to consult healthcare professionals before starting any medical regimen and acknowledges the recovery process is a slow, diligent journey akin to the duration of time taken to develop adrenal fatigue. GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://to-health-with-that.teachable.com/p/mthfr-basics GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (metylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more 00:00 - Welcome to Season Four: Tackling Fatigue 00:35 - Exploring Adrenal Fatigue: Understanding and Healing 01:05 - Nutritional Support for Your Adrenals 01:26 - Vitamin C, Magnesium, B vitamins 02:43 - Melatonin to balance cortisol 03:06 - The Power of Adaptogens in Balancing Cortisol 04:38 - Choosing the Right Supplements for You 05:19 - The Journey to Recovery: Timeline and Expectations 05:49 - Final Thoughts and Medical Disclaimer --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

In season four of the 'To Health With That' podcast, hosted by naturopathic doctor Amy Noozle, the focus shifts to understanding and combating fatigue, with a specific emphasis on adrenal fatigue. This episode discusses the importance of healing your adrenals from phase two (tired but wired) or phase three (burning down) without the immediate use of adrenal hormones or supplements, reserving such treatments for more severe cases. Doctor Neuzil emphasizes lifestyle changes as a crucial step towards adrenal recovery, advocating for consistent sleep schedules, reducing screen time before bed, ensuring exposure to bright light in the morning, and adjusting dietary habits to support adrenal health. The significance of mindset and doing less than one is capable of to avoid further stress on the adrenals is highlighted as the hardest yet most vital part of recovery. The episode promises to cover supplements in the following installment. GENETIC ROCKSTARS (an MTHFR community): https://community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://to-health-with-that.teachable.com/p/mthfr-basics GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (metylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more 00:00 - Welcome to Season Four: Tackling Fatigue 00:29 - Healing Your Adrenals: Lifestyle Over Supplements 01:23 - Understanding Adrenal Fatigue: Tired but Wired to Burned Out 02:25 - Adrenal Healing Lifestyle: From Sleep to Diet 03:14 - Restoring Circadian Rhythm 03:51 - Morning Light, Evening Dark 04:33 - Water and Salt Balance 04:58 - Adrenal Health Diet 05:27 - Now Isn't The Time To Be A Marathoner 06:47 - Mindset: The Key to Healing Adrenal Fatigue 07:40 - Looking Ahead: Supplements for Adrenal Support --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

In this episode of the 'To Health With That' podcast, host Amy Neuzil, a naturopathic doctor, explores adrenal fatigue, a widespread issue attributed to the constant stress of modern life. The episode delves into the four stages of adrenal fatigue: 'Crushing it,' where individuals feel highly productive and energized due to high cortisol levels; 'Tired but wired,' marked by emerging fatigue and anxiety; 'Burning down,' where symptoms worsen, including greater fatigue and sleep issues; and 'Burned out,' a phase of significant functional impairment. Neuzil emphasizes the importance of early detection and intervention to prevent reaching the burnout stage. The episode aims to educate listeners on recognizing the signs of adrenal fatigue and offers a lead into the next episode, which will focus on non-hormonal strategies for nourishing and healing the adrenals. GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://to-health-with-that.teachable.com/p/mthfr-basics GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (metylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more 00:00 Welcome to Season Four: Unpacking Fatigue 00:36 Exploring Adrenal Fatigue: Understanding the Basics 01:49 Stage 1: Crushing It with High Cortisol 03:22 Stage 2: The Tired but Wired Phase 05:00 Stage 3: The Burnout Begins 06:24 Stage 4: Total Burnout - The Final Stage 07:36 Recovery and Prevention Tips 07:53 Wrapping Up and What's Next --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Understanding and Addressing Adrenal Fatigue Adrenal fatigue is everywhere in modern culture, but why is that? It comes down to the difference between threats in our ancestral (geneticly adapted) cultures and threats in modern life. Dr. Amy explains the role of the adrenal glands, located like hats on the kidneys, in secreting hormones that regulate our stress response and circadian rhythms. She discusses how modern stressors, unlike ancestral dangers, continuously trigger our fight or flight response without the necessary physical release, leading to what is commonly referred to as adrenal fatigue. Symptoms range from overwhelming fatigue to more severe conditions like Addison's disease in extreme cases. The episode finishes with a mention of Debbie Moon's book, 'Histamine Life Hacks,' recommending it for further reading on histamine issues. Future episodes promise to explore the stages of adrenal fatigue, its impact on health, and potential recovery strategies. 00:00 - Intro 00:29 - Diving Deep into Adrenal Fatigue 01:00 - Understanding Your Adrenals: The Basics 03:25 - The Modern World vs. Our Adrenal Health 05:39 - Symptoms and Testing for Adrenal Fatigue 08:20 - A Quick Book Recommendation: Histamine Life Hacks 08:59 - Looking Ahead: Navigating Adrenal Fatigue Here's the amazong link (affiliate) for Histamine Lifehacks: https://amzn.to/3QtduV5 Thanks for watching this video! Here are some links you might like. Schedule a free 15-minute meet and greet with Dr. Amy to see if we're a good fit to work together in group coaching: https://calendly.com/amy-tohealthwiththat/15min More about group coaching: https://www.tohealthwiththat.com/group-coaching/ Genetic Rockstars (first month free for my YouTube peeps!): https://community.tohealthwiththat.com/plans/204575?bundle_token=4da8ed9c5f00a92363bcd15ad2ac26dd&utm_source=manual FREE MTHFR Basics course: https://courses.tohealthwiththat.com/p/mthfr-basics Support our work by using affiliate links when you buy supplements and resources: Seeking Health: https://bit.ly/3afXYH4 Amazon: https://www.amazon.com/s?k=Health+best+sellers&i=stripbooks&camp=1789&creative=9325&linkCode=ur2&linkId=29fff6e3ea954499d2eed32d46428454&tag=tohealthwitht-20 Fullscript (for other supplements): https://ca.fullscript.com/welcome/aneuzil Queen of The Thrones Castor Oil Packs:  https://shop.queenofthethrones.com/amy-tohealthwiththat For 10% off any order of $59 or more, use the code AMY_TOHEALTHWITHTHAT10 --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Doing a good detox protocol takes some preparation and some of the best preparation you can do is finding out if your genes are making detoxification harder for you somewhere. Some gene SNPs have the potential to make detox harder by interfering with phase two conjugation reactions. These include MTHFR, MTR, MTRR, GST, GPX, COMT, HNMT, UGT1A1, SULT genes, NAT1, and NAT2. With each category of gene SNP, I will also give suggestions for improving that aspect of your phase two detoxification reactions. 00:00 - Intro 00:49 - Why SNPs matter and how to test 02:08 - Genes that affect methylation and how to help 02:46 - Genes that affect glutathione and how to help 03:38 - Genes that affect sulfation and how to help 04:20 - Genes that affect glucuronidation and how to help 05:52 - Genetic Rockstars walkthrough 07:42 - Genes that affect acetylation and how to help 08:11 - Amino acid conjugation GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://to-health-with-that.teachable.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we're a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (methylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Detox is amazing for your body, so why does it feel so awful? The great news is that symptoms of detoxification may be helpful in giving your signals about what is happening. We'll quickly review phases I - III of detoxification, why things can feel bad, where detoxification gets stuck, and how to plan for an easier detoxification. 00:00 - Intro 00:58 - 3 phases of detox 02:54 - detox uses energy and resources 04:24 - Four reasons why detox feels bad 06:31 - Plan ahead for easier detox 07:21 - Symptoms of detox GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://to-health-with-that.teachable.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we're a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (methylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

In the last episode, we discussed the fact that toxins come from food, air, water, personal care products, and pretty much everything we encounter. Detoxification is an ongoing process that is always at work in your body. Here are the basics about how detoxification happens, what resources your body needs, and why it sometimes feels yucky. Detoxification happens in three phases. Phase one involves chemical reactions, mostly in the cytochrome P450 system. Phase two comprises conjugation reactions so that substances can be transported out of the tissues, and phase three is the active transport of these toxins out of your tissues and into waste material. 00:00 - intro 00:29 - Why Detox is easy to get wrong 01:19 - Three phases of detoxification 01:40 - Detoxification Phase one and cytochrome P450 system 02:31 - Genetic Rockstars quick walk-through 04:36 - Detoxification Phase two, conjugation reactions, and gene SNPS 05:15 - Phase three reactions and toxin transport 05:43 - You have to eliminate to detox 06:26 - Water and detox 06:50 - Limit toxin exposure 08:05 - Detox uses energy and nutrients 09:01 - Practitioner support and detox kits GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we're a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (metylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Toxins are everywhere in modern life, and they have always been a normal part of life because they come from food, bacteria, mold, yeast, air, water, and the soil. Also, now, industrial and agricultural chemicals, the products we use on our skin, teeth, hair, and nails, and things we use to care for our homes like air fresheners, cleaning products, and that sort of thing. Toxins are everywhere and they can accumulate in your system causing symptoms like fatigue, exhaustion, brain fog, weakness, poor memory, difficulty concentrating, skin outbreaks, constipation, and irritability. Let's talk about where toxins come from and how toxins make you feel, and this will start our short mini-series on detoxifying. 00:00 - Intro 00:35 - Where toxins come from 01:24 - Detox is always happening 02:06 - Why toxins cause fatigue 02:48 - Toxicity is a vague term 03:39 - General toxic symptoms 04:00 - Voluntary toxins 04:42 - Drugs and supplements 06:36 - Surgical toxins 07:05 - Toxins and genes 08:20 - Cytochrome P-450 09:11 - What is coming up in the toxin mini-series GENETIC ROCKSTARS (an MTHFR community): https://community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we're a good fit to work together or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (methylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Problems with oxygenation can affect your sleep quality and quantity, leaving you feeling tired, or like you slept but woke up as tired as you were the night before, or just plain exhausted. Iron deficiency and carbon monoxide poisoning are both oxygen problems, not that we think of them that way, but many oxygen problems are more subtle. The classic oxygen problem overnight is sleep apnea, which causes you to wake up through the night becuase you stop breathing momentarily. Mouth breathing at night also impairs oxygen and leads to fatigue, low energy, and a poor night's sleep. My favorite solution to this problem is mouth taping. 00:00 - Intro 00:40 - Iron deficiency and carbon monoxide poisoning 01:55 - Sleep Apnea 02:21- Types of Sleep Apnea 03:08 - Sleep apnea treatment 03:36 - Sinuses and fatigue 04:07 - Mouth breathing and fatigue 05:15 - Why mouth breathing causes fatigue 05:45 - Three differences between breathing through your nose and mouth 07:05 - Fix mouth breathing with mouth taping GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we're a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (metylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Sex hormones have a lot to do with how energetic you feel, or how sleepy, or how grumpy. So, let's talk about how estrogen ties into sleep, weight, and metabolism. How progesterone helps insomnia and gets stolen by stress hormones. Also, how testosterone is a feel-good chemical. We'll also talk about xenoestrogens, which come from outside your body, and how to reduce estrogen, boost progesterone and testosterone, and generally find hormone balance. 00:00 - intro 00:29 - What sex hormones do 00:59 - Estrogen and metabolism 01:40 - Estrogen dominance 02:03 - Xenoestrogens (estrogen from chemicals) 02:25 - Two ways to manage estrogen levels 02:30 - Avoid estrogen from chemicals 03:43 - Detoxify estrogen better 03:53 - Estrogen detox needs good methylation 05:00 - Progesterone, sleep, and stress 06:25 - Testosterone and wellbeing 07:04 - High estrogen causes low testosterone 07:48 - Men need weight bearing exercise 08:02 - Losing weight leads to estrogen spikes 08:20 - Supplements for Testosterone 08:38 - Energy changes in menstrual cycle 09:26 - The bottom line GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we're a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I get a small profit when you choose to buy from these links, so thank you! SEEKING HEALTH (methylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

There is nothing more frustrating than waking up in the middle of the night and not being able to go back to sleep easily. Nighttime waking is draining and exhausting, and you wake up feeling like you might as well not have bothered with all of those hours of tossing and turning. So, what can you do to help you sleep through the night without waking up? Let's talk about some options. 00:00 - Intro 01:13 - Time release melatonin 02:23 - Night-time blood sugar spikes 02:35 - Dawn Phenomenon 03:08 - Night waking with "normal" blood sugars 03:31 - Diet changes for blood sugar overnight 04:05 - Supplements for overnight blood sugar 05:00 - Prescription changes for nighttime waking in diabetes 05:19 - Night-time cortisol spikes 06:23 - Supplement to manage overnight cortisol 07:07 - Histamine spikes at night 07:46 - Supplements to lower histamine at night 08:18 - Hormones and insomnia 09:04 - Supplements to help preserve progesterone --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Supplements to help you fall asleep are a big topic, and there are many to choose from, but these are my favorite supplements to get you to sleep faster. GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we're a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: go.tohealthwiththat.com/watch-the-free-videoWEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I get a small profit when you choose to buy from these links, so thank you! SEEKING HEALTH (methylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more 00:00 - Intro 00:49 - Make sure you're not taking something that keeps you awake 01:13 - Special precaution with MTHFR 01:57 - Body won't relax 02:28 - Magnesium 03:15 - Opposite reaction to magnesium 03:30 - GABA 03:57 - Passionflower 04:15 - Agitated mind 04:34 - Valerian Root 04:58 - Bifidobacterium longum 1714 05:42 - Aromatherapy 06:23 - Chamomile 06:58 - Glycine 07:25 - Melatonin 09:18 - Next episode --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

MTHFR gene mutations can create a lot of havoc in your life if they aren't properly managed and sleep disorders are just one of the many problems. This video will talk about the most impactful morning and evening sleep routines for MTHFR and also give some tips for the best diet to support great sleep in a person wtih the MTHFR gene mutation. GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we're a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: mmm.tohealthwiththat.com WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I get a small profit when you choose to buy from these links, so thank you! SEEKING HEALTH (metylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more Chapters: 00:00 - Intro 00:35 - Methylation and sleep 01:00 - Mental factors in sleep problems with MTHFR 01:18 - Physical contributors to sleep problems with MTHFR 01:38 - Right folate plus right methyl donors 02:17 - How to find your perfect doses 03:09 - Synthetic folic acid and sleep 03:40 - Blood sugars and sleep 04:25 - Best bedtime routine for great sleep with MTHFR 07:16 - Best morning routine to help sleep with MTHFR 08:12 - Activities to include in your day for great sleep with MTHFR If you know or suspect you have MTHFR or a methylation issue, be sure to subscribe to the podcast for health tips, MTHFR hacks and great information. --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Sleep anxiety is the horror circle that lies at the intersection of insomnia and anxiety disorders that createes a torturous loop in which a person is worried they won't sleep, and the anxiety ironically prevents them from sleeping. Nightmare. Here's the link to the breaking mental bad habits video: https://youtu.be/5rpKe_hsk3Y?si=8IgE1AlhjsqiPtjx 00:00 - Intro 00:30 - What is sleep anxiety 01:19 - How sleep anxiety arises 02:09 - Origins of sleep anxiety 03:04 - Sleep disorders and medication changes 03:44 - Ritualized sleep routine 04:56 - Vigorous exercise 05:37 - Ignoring sleep completely 06:48 - Cognitive Behavioral Therapy -Insomnia 07:45 - Prescription medications 08:29 - Breaking mental bad habits --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

There are four big categories of sleep disorders and today we'll talk about the last two. Numbers one and two were in the last episode, so if you missed that, check it out here: https://youtu.be/D49k6TlaA_Y?si=It4iWPevrXZnK4d1 The third pattern is is hard time falling asleep AND staying asleep and number four is for people who feel like they sleep, but wake up feeling unrested, as though the sleep didn't do anything. Taking a look at your sleep pattern can help you to figure out what is actually causing your bad sleep and how you can fix it. We'll talk about the most common causes of each pattern including true insomnia, sedentary lifestyle, pain, histamine, cortisol, blood sugar, anxiety, and waking to pee. Also - here's the link for ONE MONTH FREE In Genetic Rockstars: https://community.tohealthwiththat.com/plans/204575?bundle_token=4da8ed9c5f00a92363bcd15ad2ac26dd&utm_source=manual 00:00 - intro 00:54 - Difficulty Falling And Staying Asleep 01:05 - True Insomnia 01:48 - CBT-I 02:12 - Medication Withdrawal and Dosage Changes 03:02 - Anxiety, Pain, and Histamine 03:27 - Genetic Rockstars 04:45 - Sleeping, but Waking Up Unrested 05:03 - Iron and Blood Oxygenation 05:50 - Sleep Apnea 07:00 - Mouth Breathing --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

There are four big categories of sleep disorders and today we'll talk about the first two. Number one is hard time falling asleep and number two is hard time staying asleep. Taking a look at your sleep pattern can help you to figure out what is actually causing your bad sleep and how you can fix it. We'll talk about the most common causes of each pattern including melatonin issues, magnesium deficiency, iron deficiency, sedentary lifestyle, pain, histamine, cortisol, blood sugar, anxiety, and waking to pee. 00:00 - intro 00:57 - Difficulty Falling Asleep 01:06 - Low Melatonin 01:27 - Sunlight in the morning 01:46 - Screen Free time before bed 02:02 - Magnesium Deficiency 02:28 - Iron Deficiency 02:59 - Not getting physical activity 03:23 - Pain 03:35 - High Histamine 04:27 - Waking up in the Night 04:42 - High Cortisol 05:08 - Nighttime cortisol spikes 05:43 - Blood sugar 06:28 - Nighttime Anxiety 07:34 - Restless Legs 08:02 - Histamine spikes caused by alcohol 08:31 - Waking to go to the bathroom --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Sleep is one of our basic bodily functions and a key to good daytime energy and productivity. We'll talk about what sleep is, what it's for, and the basic sleep phases. We will also talk about the role of MTHFR in sleep and also the link between sleep and circadian rhythms. We'll also list eight key ways to maintain a healthy sleep wake cycle for the best, most restful sleep. 00:00 - Intro 00:50 - What is sleep 01:20 - What sleep is for 01:39 - Phases of sleep - REM sleep 02:44 - Non-REM sleep 03:33 - MTHFR and sleep 04:32 - Circadian Rhythms 06:00 - Sleep Hygiene 06:16 - 8 tips for a good sleep-wake cycle 09:07 - Like and subscribe, or leave a good review, please! :) --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

While we're talking about fatigue, it's important to also talk about what helps you feel energetic, because sometimes knowing what gives you energy can help you understand what is going wrong. We'll talk about sleep, hormones, cellular energy, neurotransmitters and energy, and also rest and energy. 00:00 - Intro 00:55 - What Is Energy? 01:28 - Thyroid and Energy 02:29 - Adrenals and Energy 03:40 - Sex hormones and Energy 04:34 - Neurotransmitters and Energy 04:50 - Histamine and Energy 05:29 - Calories, Nutrients, and Energy 06:40 - Best diet for Energy 07:12 - Cellular Energy 08:04 - Sleep, Rest, and Energy --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Depression and fatigue look incredibly similar, but we treat them totally differently. Maybe it's time for treatment strategies to begin to overlap. We'll talk about how these two conditions intermix, and how you can begin to address both of them. 00:00 - Intro 00:35 - Depression and Fatigue are circular 01:42 - Depression isn't only neurotransmitters 02:14 - Sickness behavior and depression 03:18 - Symptoms unique to depression 03:33 - Why fatigue affects mental health 03:59 - Symptoms unique to sickness behavior 04:26 - Amy's neurotransmitter theory 05:50 - How do we treat fatigue/depression? Ketamine, glutamate inhibitors 06:46 - Natural remedies that address both - saffron, St. John's wort, fish oil, vitamin D, creatine, NAC 08:14 - New drug therapies - psilocybin, ayahuasca, nitrous oxide 09:16 - Why nitrous oxide is bad for people with MTHFR --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

The first step to tackling your fatigue and getting your energy back, is finding out if there is something underneath, causing the fatigue, that you can fix quickly. Some of these simple fixes might need some bloodwork from your doctor, and some will require you to do detective work on your own. The very simple fact is that you can't fix it unless you can find it, so here are the basic steps you can go through. We will talk about iron deficiency, ferritin, thyroid, sleep apnea, carbon monoxide poisoning, MTHFR, blood sugar fluctuations, and more. --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Fatigue and exhaustion are going around - we are all struggling. But why? What is really going on here? What is fatigue, what causes it, and why does everybody I know have it? We'll do a quick overview of the causes of fatigue, including lack of resources, poor sleep, chronic stress, and all the rest. We'll talk about how your body protects itself sometimes by getting tired and lifestyle factors that play into it. Genes are also important with fatigue, but the research is shockingly scarce. 00:00 - Intro 00:29 - What is fatigue? 03:03 - Sickness behavior (protective fatigue) 04:04 - Lifestyle factors to fatigue 05:00 - Why there is hope for fatigue 05:14 - Gene SNPs and fatigue 07:48 - Fixing fatigue 08:40 - Podcast season 4 outline 09:36 - Outro --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

I have enjoyed this season so much - the interweaving of MTHFR and fertility and the ever-interesting conversation about women's health and hormones. Huge thanks to Dr. Kate Naumes, who made the season so much fun. Without further ado, it is time for the season 4 topic announcement - because this is the #1 symptom that people with MTHFR (and people without it) complain about. This topic is tied up in everything from basic metabolism to hormones, from neurotransmitters to methylation, and from cellular energy to viral load. Have you guessed it? Next season's topic will be: Fatigue, Chronic Fatigue, and Your Genes. We'll keep MTHFR and other gene SNPs the whole way through while we uncover all the different facets of fatigue. As always there will be so many things you can start doing today to help your body have more energy and keep the fatigue at bay. We'll discuss: Everything that goes into your resting energy level Why fatigue is so damn common What MTHFR (and COMT, and MTRR, and many more gene SNPs) have to do with it What is really happening when fatigue becomes chronic How toxins and toxic burden play into it Boosting cellular energy And so much more. Enough to fill a whole season. I can't wait to get started. The the first episode will air the Sunday after Labour Day (that's September 10th, 2023.) Thanks again to Dr. Kate Naumes, ND. Working on optimizing your genes? Join Genetic Rockstars today.  Check out courses on MTHFR and seed cycling here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

There is a new fad diet every 20 minutes, or at least it feels that way. It could be paleo, ancestral, keto, the potato diet, the grapefruit diet, the bean diet, and the list goes on. So, how are these fad diets generally, and how are they for fertility? The thing about fad diets is that they work for some people, under some conditions, and for some period of time. Often, however, they provide an unbalanced nutrient profile that is not conducive to building a healthy baby. Also, there is the sensitive issue of eating disorders, which are often undiagnosed and untreated. So let's discuss. Here is the video version of Dr. Kate and Dr. Amy. Working on optimizing your genes? Join Genetic Rockstars today.  Check out courses on MTHFR and seed cycling here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

The best diet for fertility sounds like a big claim to make, but the science is clear about what is needed and what isn't. This episode we'll talk about: What part of the BMI normal range is best for baby-making Basic diet guidelines that are simple to follow Why fruits and vegetables matter so much Why the Mediterranean diet is so effective Why more good fats are a good thing in pregnancy The true story about caffeine and alcohol Which part of the pregnancy is the most important part to stick to your diet Check out the video version of Dr. Kate and Dr. Amy having this conversation. Working on optimizing your genes? Join Genetic Rockstars today.  MTHFR courses are here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Of course there is a perfect way to do things if you have all the money, time, and resources to throw at it, but what about what actually happens in real life? Because let's face it, we're all dealing with medicine IRL. This week we'll talk about: The barriers to good fertility care including insurance or lack of insurance, time, money, location, and more. What you can do to maximize your fertility care even when you have some of those barriers (as we all do) The things you can take care of at home to boost your chances Resources you can have on hand to get the most out of every medical visit Fertility medicine especially is expensive, time consuming, and extremely demanding and it can make a huge difference to your outcomes and also to how much money you end up spending if you're prepared. Check out the video version of Dr. Kate and Dr. Amy talking this one through. Working on optimizing your genes? Join Genetic Rockstars today.  Check out courses on MTHFR and seed cycling here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

This week we're talking about "advanced maternal age" which is the medical term for women having babies over the age of 35. The real problem here comes down to oocyte aging, or aging eggs, which is related to poor ovarian reserve. We'll talk about why egg quality declines with time, what sort of testing your doctor will run, the difference between poor ovarian reserve and advanced maternal age, the options for women trying to get pregnant, lifestyle and supplements for oocyte aging and to increase egg quality, and also advanced paternal age, or old sperm. 00:00 - Intro 00:28 - Why egg (oocyte) quality declines with time 03:07 - Testing for oocyte quality 04:56 - Poor ovarian reserve vs. advanced maternal age 06:57 - Options for women with oocyte aging 08:36 - Lifestyle and supplements for oocyte aging 11:11 - Advanced paternal age 13:49 - Outro Here's the video version of Dr. Kate and Dr. Amy talking this one through. If you're working on your health by balancing gene SNPs and epigenetics, join Genetic Rockstars. If you'd like to take a course on MTHFR, click here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Iron deficiency anemia can be a significant problem when you're trying to conceive or going into a pregnancy, but even without overt iron deficiency anemia, your iron levels can still have an effect. We'll discuss: Why it's important to test both red blood cell iron levels and also ferritin, the storage form of iron. What iron deficiency anemia feels like, normally and in pregnancy. The possible complications of anemia in pregnancy, childbirth, for the neonate and even for the child of an anemic mother beyond the neonatal period. The relationship between men's iron levels and men's fertility especially with sperm parameters. Iron infusions and why we love them. Iron levels are an important factor in preconception and pregnancy and while every doctor will test basic red blood cell levels, you may have to advocate for yourself to get your ferritin tested. Here's the video version of our chat. Have genetic polymorphisms? Work on them in the private community, Genetic Rockstars. If you'd like to take a course on MTHFR, click here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Overtly low or overtly high thyroid levels are a well known risk factor for infertility, but today we're going to talk about something a little bit less well known, which is subclinical hypothyroid and fertility. Subclinical hypothyroid is when the thyroid tests are on the lower end of normal, but still within normal limits. The patient experiencing this might have symptoms of mild low thyroid, or might be asymptomatic, but research is showing a link between this "normal" thyroid and fertility difficulty. We'll talk about: The effects of high and low thyroid on women's fertility The suprising effect of low-normal thyroid levels on fertility Thyroid testing TPO antibodies (or thyroid peroxidase antibodies) and their effects on fertility in women with normal thyroid levels Thyroid hormones and when they are prescribed for women in fertility situations The effects of hyperthyroid and hypothyroid on sperm levels and sperm morphology (that is high and low thyroid function) Routine thyroid screening in pregnancy How naturopathic doctors can help Thyroid is a known cause of fertility difficulty, but not all doctors are aware of the link between low-normal thyroid function and impaired fertility. Follow this link for the video version of Dr. Kate and Dr. Amy talking this one through. If you have MTHFR and want to work on it with an amazing group of other folks with genetic polymorphisms, join Genetic Rockstars. If you'd like to take a course on MTHFR, click here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://anchor.fm/tohealthwiththat/message

MTHFR is involved in so many processes, but it is especially tangled up with fertility for both male and female partners, as well as pregnancy for female partners. This episode we'll talk about: Male factor infertility, sperm count, and sperm morphology 5-LMTHF vs. folic acid use in this situation - what is the standard of care, vs. what might actually work better Repeat pregnancy loss The possible factor of microclotting Homocysteine levels in pregnancy - normal and abnormal Hope in the MTHFR and fertility journey. Here's the video version of Drs Kate and Amy talking about it. If you have genetic polymorphisms, join the amazing community called Genetic Rockstars. Or, take a course on MTHFR. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://anchor.fm/tohealthwiththat/message

The infertility journey can be a difficult path and is often an endurance race with sprints mixed in. This episode is less about mental health expertise, we will defer to therapists, counselors, and mental health professionals for that, and more about starting a conversation around some of the issues we see commonly in our practices. Four of the big ones that come up are: Self worth, self image, masculinity and femininity The timed sex problem (because making sex a task-based activity takes a lot of the magic out of it) Actual loss Not getting the thing you want, only makes you want harder We'll also talk about the link between the increasing stress of infertility, and stress making it harder to conceive. Additionally, Dr. Amy will mention a couple of homeopathic remedies that are useful in the infertilty space as a support to help you heal. Dr. Kate and Dr. Amy both encourage you to take mental health as seriously as you do your physical health and we hope this episode can encourage some conversations with friends, loved ones, or mental health professionals. See the video version of Dr. Kate and Dr. Amy talking this one through. If you have genetic polymorphisms and want to work on them with an amazing group of other folks with genetic polymorphisms, click here. If you'd like to take a course on MTHFR, click here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://anchor.fm/tohealthwiththat/message

PCOS is one of the more common causes of female-factor infertility because it creates a situation in which ovulation is unpredictable or not occurring and babies can't be made if no good eggs are released. Dr. Kate and Dr. Amy will talk about The diet they typically suggest for PCOS Why a PCOS diagnosis is commonly missed Inositol for PCOS The difference between working with PCOS for clients on a fertility journey vs. clients who are just looking for health Supplements used for PCOS. For the full video version of Dr. Kate and Dr. Amy talking this one through, click here. If you have genetic polymorphisms and want to join the most amazing group of other folks with genetic polymorphisms, click here. If you'd like to take a course on MTHFR, click here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://anchor.fm/tohealthwiththat/message

Last week we talked about how endometriosis affects fertility and pregnancy outcomes. This week, let's dive deeper into what is really going on with endometriosis and why it has such far reaching effects for women. We'll discuss Gene SNPs associated with endometriosis The link between inflammation and endo Endometriosis and oxidative stress Treatment goals with endo Association between endometriosis and autoimmune disease, depression, migraines, and more. To see a video version of Drs Kate and Amy talking this one through, click here. If you have genetic polymorphisms and want to work on them with an amazing group of other folks with genetic polymorphisms, click here. If you'd like to take a course on MTHFR, click here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://anchor.fm/tohealthwiththat/message

Endometriosis is one of the leading causes of female factor infertility and it's responsible for incredibly painful menses, heavy bleeding, and often pain with intercourse as well. This week we'll talk about the links between endometriosis and fertility and next week we'll deep dive into some of the underlying causes, including inflammation and hormone imbalances. We'll also talk about the value of integrative medicine indulging main stream medical practice with naturopathic care specifically for endometriosis. For the video version of Drs Kate and Amy talking this through, click here. If you have genetic polymorphisms and want to work on them with an amazing group of other folks with genetic polymorphisms, click here. If you'd like to take a course on MTHFR, click here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://anchor.fm/tohealthwiththat/message

Lots of people come to NDs to help them on their fertility journey, but what does an ND actually do? In short, your ND can support your fertility journey in a lot of ways, no matter where you are in the process. We can Balance your hormones and help you with preconception (for both sperm and egg donor) so your baby can have the healthiest start Help to get your body ready for Assisted Reproductive Technology like IVF Help you to reduce the side effects of Assisted Reproductive Technology and other fertility interventions An ND that focuses on reproductive health and fertility can help you at any stage of the journey, whether you're in the early days, or you've been through three rounds of IVF and you're considering a surrogate. For the video version of Dr. Kate and Dr. Amy talking this one through, click here. If you have genetic polymorphisms and want to work on them with an amazing group of other folks with genetic polymorphisms (Genetic Rockstars), click here. If you'd like to take a course on MTHFR, click here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://anchor.fm/tohealthwiththat/message

The idea of getting an infertility evaluation is a daunting one, but it gives you such a wealth of valuable information and can help you to steer your treatment in the right direction, for both potential parents, without wasting precious time. Let's talk about: The best doctors to visit for this, and how to get it if you're in an area with limited health resources. When to get a complete infertility evaluation Why it matters for both partners What tests are included in an infertility evaluation for men and women How Ovarian Reserve is assessed Why the uterus and fallopian tubes might need investigation and how that is done For the full show notes including a video version of Dr. Kate and Dr. Amy recording, click here. If you have genetic polymorphisms and want to work on them with an amazing group of other folks with genetic polymorphisms, click here. If you'd like to take a course on MTHFR, click here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://anchor.fm/tohealthwiththat/message

This week we're talking about a basic tool in every woman's arsenal, it's tracking her period and charting her cycle. Especially on the fertility journey, knowing when you're ovulating and your most fertile window is invaluable, and knowing if you ovulate at roughly the same time every month gives you a great indicator of how things are going in your body right now. We'll talk about: Why to use the Fertility Awareness Method of Cycle charting Who this might not be right for Why we're not suggesting paper tracking vs. period tracker apps in the US How to tell when you're ovulating A great resource to learn more. For the show notes including a video version of Drs. Kate and Amy talking this one through, click here. If you have genetic polymorphisms and want to work on them with an amazing group called Genetic Rockstars, click here. If you'd like to take a course on MTHFR, click here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://anchor.fm/tohealthwiththat/message

Folic acid is the standard of care for both prenatal vitamins and high doses for couples struggling with infertility. So let's look at a compelling research study about using 5-LMTHF as an intervention instead of folic acid for couples who have been struggling with infertility for four years and have already failed high-dose (5000 mcg) folic acid. We'll talk about The potential risks of 5000 mcg folic acid in pregnancy UMFA and the dangers of unmetabolized folic acid A remarkable study that helped 27/33 couples get pregnant after FOUR YEARS of infertility The difference between people who have an MTHFR mutation and people who don't. Research that you can take to your care team if you'd prefer to try 5-LMTHF instead of folic acid. For the full show notes including the full video conversation between Dr. Kate and Dr. Amy, click here. If you have genetic polymorphisms and want to work on them with a fantastic group of other folks with genetic polymorphisms, click here. If you'd like to take a course on MTHFR, click here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://anchor.fm/tohealthwiththat/message

Seed Cycling sounds too simple to work, but it's a lovely nutritive way to get your menstrual cycle back in balance. This technique uses a combination of four seeds, flax seeds, pumpkin seeds, sesame seeds, and sunflower seeds, to balance and regulate hormones. Seed cycling can help to: Reduce heavy bleeding Reduce cramping Decrease frequency and/or severity of hormonal migraines Regulate cycle length Reduce severity of PMS For the full show notes including a video version of Dr. Kate and Dr. Amy talking this one through, click here. If you have genetic polymorphisms and want to work on them with an amazing group of other folks with genetic polymorphisms, click here. If you'd like to take a course on MTHFR, click here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://anchor.fm/tohealthwiththat/message

There are so many women's hormone symptoms that women have regularly that we think of as a "normal" part of being a woman, but that might give you some good clues about your fertility. This week we'll expand on this topic from last week and go over symptoms like pelvic pain, cramping, PMS, PMDD, fatigue, chronic acne or hormonal acne, lower abdominal bloating, fatigue, hot flashes and night sweats, unexplained weight gain, pain with sex, low sex drive or low libido, infertility or difficulty getting pregnant, sores that won't heal, a sudden change in your period, and spotting. For the full show notes including the video version of Drs Kate and Amy talking, click here. If you have genetic polymorphisms and want to work on them with an amazing group of other folks with genetic polymorphisms, click here. If you'd like to take a course on MTHFR, click here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://anchor.fm/tohealthwiththat/message

There are lots of red flags in every day life that might indicate a hormone imbalance or other problem that could have fertility consequences. This week we'll talk about the first ones, including: Skipped or missed periods Heavy bleeding or flooding Scanty bleeding (even though it makes for a nicer period) Abnormal hair growth Hair loss Next week, we'll go over more red flags because women's hormones can go crazy in so many ways. For the full show notes including a video version of Dr. Kate and Dr. Amy talking this one through, click here. If you have genetic polymorphisms and want to work on them with an amazing group of other folks with genetic polymorphisms, click here. If you'd like to take a course on MTHFR, click here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://anchor.fm/tohealthwiththat/message

Your annual exam isn't normally the place where you're looking for fertility insights, but if you know where to look there is hidden information in: Your annual bloodwork Your breast exam Your bimanual exam Your pap smear Just because it isn't "about" fertility, doesn't mean this isn't useful. Look here for the show notes with more information about other findings in your annual exam, and here if you want to join the amazing community of folks working on their genetics together, Genetic Rockstars. If you're interested in a course, click here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://anchor.fm/tohealthwiththat/message