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Frog Boy returns from his Ayahuasca Darkness retreat to grace us with his presence Leroy suffers another loss to technology The guys drag Frog Boy into their argument pitting a Shark vs Octopus Sound the Alarm as the Dolphins "lose" yet another physical practice Is it too early to hit the panic button? Taylor Swift breaks the internet with her Charismatic personality Tobin gives Prospects Pete his credit We check in on Fins joint practice as Tobin gives us Live updates We get a few injury updates as we check in on Chop and Cheetah Mike McDaniel gives us insight on whether or not the 1st team will play this weekend Leroy gives his take on the Dolphins choice to rest players Tua reveals his frustration with the Dolphins Offensive performance
Tobin starts off Hour 3 with some headlines, Shedeur Sanders apparent injury during camp today while trying to grouple with still with the news about Chop. Leroy tries to convince us of some bro science as he swears the best way to prevent an oblique injury is golf! The reports keep coming out from the Dolphins joint practices with the Lions… and lets just say they are not good! We then hear from former cornerback of the Miami Dolphins Jalen Ramsey, as he had things to say about the process of his trade to the Steelers that had the gang not too happy! We then close out the hour with our favorite Thursday game Rats Off a Ship! Taylor Swift, and a heated debate about Octapusses!
This week on The AEW-some Pod, Diana Prince, Gringo Fantastico, and Johnny Taylor ride into Roanoke for a Collision recap that's got it all—big boots, bigger pops, and… a suspicious amount of chopping. The Fletcher vs. Ishii TNT Title slugfest was about the only thing Gringo liked, Hangman lit up his home-state crowd, and Willow Nightingale tried to steal the night from an entire spooky trio. Plus—Big Bill keeps wandering into other people's matches, Ricochet's “respect tour” continues, and Harley Cameron's pink mask might be haunted. Strap in—this one's part love letter, part roast.
On this episode of A One Pint Stand, I sat down with Chip Walton, one of the creators and hosts of Chop & Brew, and Digital Content Producer for RahrBSG at BlackStack Brewing to chat all about homebrew and how Chop & Brew came to be. We had a great time and Chip shares some incredible insights about the homebrew industry and where it is headed. Cheers!This episode is proudly sponsored by Northbound Smokehouse & Brewpub, a South Minneapolis craft beer spot that has amazing eats, well-crafted beer and cocktails, and a vibe that will make you want to become a regular. If you liked the show and want to support the A One Pint Stand, consider joining our Patreon. There is some great bonus content that our Patreon supporters enjoy that give a fun peek behind the scenes.
In this episode, Robert revisits one of Warren Buffett's most famous investing ideas and asks what happens when the “wide economic moat” starts to shrink. He explores how once-unshakable giants can lose their edge, what separates a moat from a mirage, and why some advantages are built to last. From trash collection to social networks to the world's most trusted cryptocurrency, he shares examples of moats that still hold strong and what makes them different. Plus, a listener question on his most controversial investing takes and why the market's next phase could reward the patient and prepared.
Have you ever gotten the Sunday Scaries? It's an unmistakable feeling of nervousness and dread that arises the night before going to work or school on Monday morning. You may have had it as a kid, or perhaps it started when you entered the career world. Sometimes we really struggle to leave work at work, allowing our professional anxieties to permeate all of our non-working hours. Needless to say, this is not a sustainable way to live our lives given the amount of time work already requires. But how do you break the cycle when work anxiety takes hold? As we walk through the forest, learn some new tips and rituals to bring a greater sense of ease and calm to your job and your life. What am I reading?Green Teeth by Molly O'Neillhttps://bookshop.org/a/111301/9780316584241Cottage Witch's Guide to Magic by Suzanne Lemmonhttps://bookshop.org/a/111301/9781645679615https://bookshop.org/shop/witchywomanwalkingWhat's playing on repeat?Break Stuff by Limp BizkitWhat's for dinner? Israeli Couscous Roasted Broccoli Salad Ingredients: 2 cups Israeli couscous2 heads broccoli (chopped)Sun-dried tomatoes in olive oilOlives (chopped)Garlic (as much as you like)Red peppers (diced) 1 can chickpeas or white beans Chopped herbs (parsley or basil work well)Juice of one lemon Crumbled feta Olive oilSalt and pepperRed pepper flakesInstructions: Preheat oven to 375 degrees. Line cookie sheet with parchment paper. Wash and chop broccoli into small florets, spread on cookie sheet, drizzle with olive oil, season with salt, pepper, and red pepper flakes. Roast until slightly browned. Cook couscous according to instructions. Chop red peppers, olives, garlic, and sun-dried tomatoes, add to a big bowl. Then add beans, couscous and broccoli to the bowl. Finish with freshly squeezed lemon juice, fresh herbs, feta, and salt and pepper. Mix thoroughly. Enjoy! Cardamom Rose Iced LatteIngredients:Seeds from 10 cardamom pods (about 1 ¼ tsp), lightly crushed2 tablespoons dried rose petals1 ½ cups half and half or milk of choice ¼ cup organic cane sugarPot of freshly brewed coffee Ice cubesInstructions:Combine and heat the lightly crushed seeds from cardamom pods, dried rose petals, half & half or milk, and cane sugar over medium and bring to a simmer, stirring occasionally to dissolve sugar. Once simmering, remove from heat and cover.Steep 15 minutes to overnight, tasting occasionally. (If steeping overnight, refrigerate.)When the strength you desire is reached, strain through a fine mesh sieve.Brew coffee according to your preferences. Serve over ice with 1-2 ounces of cardamom rose creamer (or to your taste) to every ten ounces of coffee. Enjoy!Support the show
IBX Celebrate Caring 2025 – Honoring Nurses Who Inspire We're proud to highlight the 2025 Celebrate Caring campaign by Independence Blue Cross (IBX)—a heartfelt initiative launched during National Nurses Week that shines a spotlight on the extraordinary impact nurses make in our communities. This annual campaign recognizes nurses who go above and beyond, demonstrating compassion, resilience, and a deep commitment to those they serve both inside and outside the clinical setting. Each year, three winners are selected to receive a $500 gift card, a $2,500 donation to a nonprofit of their choice, and the Sunshine Award, named in memory of IBX executive Paula Sunshine, who helped create the program.
How Much Would It Take To Chop Off A Finger Or Two? | How Many Different Toilets Have You Used? | Adult Happy Meals Official | A List Of Common Unhygienic Things You May Have Done Or Still Do | Joke Text | A Man Who Should Never Quit, Quit | The Smell Of Jumbo Video
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Tyler and Will Hour #2 with the Roundtable and NWA Women's Champion Kenzie Paige for the Chop-o-thon! See omnystudio.com/listener for privacy information.
Tyler and Will Hour #2 with the Roundtable and NWA Women's Champion Kenzie Paige for the Chop-o-thon! See omnystudio.com/listener for privacy information.
Tyler and Will Hour #2 with the Roundtable and NWA Women's Champion Kenzie Paige for the Chop-o-thon! See omnystudio.com/listener for privacy information.
Tyler and Will Hour #2 with the Roundtable and NWA Women's Champion Kenzie Paige for the Chop-o-thon! See omnystudio.com/listener for privacy information.
Tyler and Will Hour #1 with Ridin' with Ivens and more info on the Chop-o-thon! See omnystudio.com/listener for privacy information.
Tyler and Will Hour #1 with Ridin' with Ivens and more info on the Chop-o-thon! See omnystudio.com/listener for privacy information.
Tyler and Will Hour #1 with Ridin' with Ivens and more info on the Chop-o-thon! See omnystudio.com/listener for privacy information.
Tyler and Will Hour #1 with Ridin' with Ivens and more info on the Chop-o-thon! See omnystudio.com/listener for privacy information.
More isn't always better. Our Landkmarks of OncoPharm series covers lessons learned from the ProMACE-CytaBOM regimen for NHL. ProMACE-CytaBOM: https://www.annalsofoncology.org/article/S0923-7534(20)31592-1/pdf RCT vs. CHOP (& others): https://www.nejm.org/doi/full/10.1056/NEJM199304083281404
Tune in live every weekday Monday through Friday from 9:00 AM Eastern to 10:15 AM.Buy our NFTJoin our DiscordCheck out our TwitterCheck out our YouTubeDISCLAIMER: You should never treat any opinion expressed by the hosts of this content as a recommendation to make a particular investment, or to follow a particular strategy. The thoughts and commentary on this show are an expression of the hosts' opinions and are for entertainment & informational purposes only.
1 - Will the left ever give it a rest on the trans issues? CHOP won't give up gender affirming care for minors, and this school board in California smugly looks on as constituents voice their opposition to their new rules. 115 - Dan's side answer. 120 - Is it egregious for a restaurant to not offer a baked potato as one of its starches? Your calls. 140 - Your calls to kick off the segment. Which famous person might be coming to the next Mulligan's broadcast? 150 - Replaying some of the oldies from Joe Sibilia in preparation for Tony Orlando. Can Dom get a police escort for Tony Orlando? Your calls. 155 - What is the Archbishop of Philadelphia saying about immigrants?
12 - Dom returns from vacation today and runs through the top headlines he wasn't able to discuss in his time off, including local elections in Pennsylvania. 1210 - Side - associated with the 80's 1215 - Does Trump need to work on his golf swing? 1220 - It's not Sophie's Choice, it's Shapiro's choice. Leave Mastriano out of the Trump conversation. Your calls. 1245 - Chief Economist, and Richard Aster Fellow, in The Heritage Foundation's Grover M. Hermann Center for the Federal Budget Dr. EJ Antoni joined the program after Trump struck a trade deal with the European Union over the weekend. We thought he just went to Scotland to play golf, so how did he pull this deal off? Do Europeans just not like our cars? Why does EJ think that when the Fed loses, We The People win? How will the trade and tariff talks with the Chinese go? Does EJ have a nugget for us coming down the pipeline? Was there a particular product in the grocery store that EJ looked to as a sign that inflation was halting? 1 - Will the left ever give it a rest on the trans issues? CHOP won't give up gender affirming care for minors, and this school board in California smugly looks on as constituents voice their opposition to their new rules. 115 - Dan's side answer. 120 - Is it egregious for a restaurant to not offer a baked potato as one of its starches? Your calls. 140 - Your calls to kick off the segment. Which famous person might be coming to the next Mulligan's broadcast? 150 - Replaying some of the oldies from Joe Sibilia in preparation for Tony Orlando. Can Dom get a police escort for Tony Orlando? Your calls. 155 - What is the Archbishop of Philadelphia saying about immigrants? 2 - What big guest might be coming to the Dom Show soon? Scott Presler joins us yet again as he's working hard in York County today. He tells us the story of signing up a voter while on the line with Dan. Is Scott more proud of his 40 pound weight loss or his voter enrollment? He brings us celebratory news. When is his next rally? How did Scott come to blows with a military man on X? 210 - Would Trump have won Bucks County without mail-in balloting? 215 - Dom's Money Melody! 220 - Your calls. 235 - What are the Top 10 summer reading bucks today vs 40 years ago? Why is Dom outraged at the list? Your calls. 250 - The Lightning Round!
The city, state, and country are busy planning for America's 250th anniversary in 2026, but is Philadelphia really prepared for the crowds it will bring? KYW's City Hall Bureau Chief Pat Loeb tells us what plans were unveiled this week. We have updates on several trials that captured the region's attention. The Eagles get serious at training camp, meanwhile the Savannah Bananas bring the fun and spectacle to baseball in Philly this weekend. Catch up on the week's headlines with Matt Leon and KYW Newsradio's reporting team. 00:00 Intro 02:00 What the city, state, and country are planning for America's 250th birthday 07:30 Sentencings in the killings of a CHOP doctor and a Philly SWAT officer 13:31 Verdict reached in a tragic, fatal home invasion 18:30 Eagles training camp gets underway 23:48 Savannah Bananas put on a show at their baseball tour 29:39 Beloved dinosaur from Haddonfield returns to her glory at the Academy of Natural Sciences Listen to The Week in Philly on KYW Newsradio every Saturday at 5am and 3pm, and Sunday at 3pm. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
Native Plants, Healthy Planet presented by Pinelands Nursery
Hosts Fran Chismar and Tom Knezick are back with a brand new episode of The Buzz. The burning question is are there more voices??? Listen to find out. Tom and Fran go to Cultivate “That's Hot” brings The Chop! “This or That” gives Muskrat Love in a tiny forest, while “Take it of Leaf it” has unlimited growth potential. Can we talk ferns? Did we give you a shoutout this week? Intro music by RJ Comer, Outro music by Dave Bennett. That's Hot – Fran's Plant / Tom's Plant Read Fran's Article / Read Tom's Article Have a question or a comment? Call (215) 346-6189 Have a comment? Email info@nativeplantshealthyplanet.com Follow Native Plants Healthy Planet – Website / Instagram / Facebook / YouTube Follow Fran Chismar Here. Buy a T-shirt, spread the message, and do some good. Visit Old store Here. Visit New store Here!
It's the Friday News Roundup. We're talking about the continued bike lane controversy in Center City, hotel workers represented by UNITE HERE Local 274 picketing this week because their contracts have expired, state budget delays putting SEPTA's future at risk, and Nas performing with The Philadelphia Orchestra at the Mann. Plus, host Trenae Nuri complains about potholes and executive producer Matt Katz dreams about a mysterious South Philly pool. Our Friday news roundups are powered by great local journalism: Man who struck and killed CHOP doctor riding bicycle while driving drunk sentenced to 6 to 20 years in prison How To Fix an Intersection Where potholes rule: Ranking Philly's most plagued neighborhoods Video shows vandal destroying North Philadelphia bar: 'It's wrecked' As Philly residents and schools brace for SEPTA cuts and late state funds, there's no rush for a budget in Harrisburg The property housing a former South Philly pool club is for sale and going viral Get Philly news & events in your inbox with our newsletter: Hey Philly Call or text us: 215-259-8170 We're also on Instagram: @citycastphilly Learn more about the sponsors of this episode: Babbel Framebridge Scribe Video Center Advertise on the podcast or in the newsletter: citycast.fm/advertise Learn more about your ad choices. Visit megaphone.fm/adchoices
We continue the conversation Harie
Full show - Thursday | GMD - To schedule or not? | News or Nope - Coldplay accidentally exposed an affair | The wedding day hair chop | Do you agree with these unique marriage rules? | The Diary - Day 9 | T. Hack's controversial bread rankings | Erica went all out for our photoshoot. What did Slacker do? | Stupid stories www.instagram.com/theslackershow www.instagram.com/ericasheaaa www.instagram.com/thackiswack www.instagram.com/radioerin
Classic City's own Harie Robinson Jr joins us in the Barbershop to discuss his life's journey. From his college football days at Ga Tech, to starting his own clothing line, to managing some of Atlanta's most successful Gentlemen's clubs, to opening up House Of Fresh, with Drumma Boy, to now being a podcast creator and finishing up a documentary about his journey
Text us about COMICS! Or about whatever. It's your life. We've been WAITING for this episode, Legion! Listen to our no-nonsense, spoiler-filled review of the MCU's Daredevil: Born Again season one! It's all about no more Daredevil, Kingpin eating his way to mayor, teeth as a registered weapon, and Frank being Frank in all his Punisher GLORY! Let's talk The Man Without Fear!New Episodes Every Week, mostly!Support us on Patreon! Get exclusive content! https://www.patreon.com/legionofcc SUBSCRIBE HERE: https://bit.ly/LegionOCCBrett Garwood - Man Behind The Curtain: https://redbagmedia.com/Our totally rad intro music comes from: Alex at Chop.it.up.productionsListen to our Podcast - Legion of Comic Correction - on all major podcasting platforms!Legion Website: legionofcc.comLCC Facebook: https://www.facebook.com/LegionofCC LCC Instagram: https://www.instagram.com/legionofcc/Support the show
A bride is going viral for chopping off a lot of her hair in between her wedding ceremony and her reception. Are you as upset about this as Slacker is?
July 16, 2025. Week 29. What is a natural history study (NHS)? And why do we care? We care because we haven't done this before, heal those born with disease. Natural history studies, which examine the progression of a disease over time, can be either retrospective or prospective. Retrospective studies analyze existing data, like medical records, while prospective studies collect new data over time. Both types are valuable for understanding a disease's course and informing research and treatment strategies. NHS are critical for clinical trial design. Size and Quality matter. Validated scales are better than PROs regardless of what the current rhetoric is. What's going on now? USA - https://curesyngap1.org/resources/studies/syngap1-ProMMiS/ - 135+ over three sites, some with FOUR visits, and counting - Adding GCP - Collaborating with world class institutions and excellent clinicians at Stanford, Children's Colorado and, of course, CHOP. USA - https://Citizen.Health/partners/srf has almost 300 patients! Retrospective Health Data. USA - https://rare-x.org/syngap1/ is where we collect PROs. Australia - Dr. Sheffer is running a study, talk to her or Dani. Latin America - SYNGAP1 Argentina with others joining. Europe - https://www.patre.info/syngap1/ Key takeaways for Industry SYNGAP1 is well positioned to work with… Vlasskamp and Wiltrout are published, Citizen Health is growing & ProMMiS is truly exceptional – and growing, and Rare-X is collecting eight key PROs. Additionally, there are significant international efforts in Australia, Latin America & Europe. Census: https://curesyngap1.org/blog/syngap1-census-2025-update-55-in-q2-2025-total-1636/ If you are in industry and thinking about starting another NHS for your asset, please don't. Please instead partner with existing PAGs and NHS studies in your key geographies to move faster, have bigger N and not waste precious patients time, we need to accelerate drug development not slow it down by diluting patients and clinicians between too many studies. Baseline papers on SYNGAP1: 1998 - Huganir - SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family - https://pubmed.ncbi.nlm.nih.gov/9581761/ 2009 - Michaud - Mutations in SYNGAP1 in autosomal nonsyndromic mental retardation - https://pubmed.ncbi.nlm.nih.gov/19196676/ 2013 - Carvill - Targeted resequencing in epileptic encephalopathies identifies de novo mutations in CHD2 and SYNGAP1 - https://pubmed.ncbi.nlm.nih.gov/23708187/ 2019 - Vlasskamp - SYNGAP1 encephalopathy: A distinctive generalized developmental and epileptic encephalopathy - https://pubmed.ncbi.nlm.nih.gov/30541864/ 2023 - Rong - Adult Phenotype of SYNGAP1-DEE - https://pubmed.ncbi.nlm.nih.gov/38045990/ 2024 - Wiltrout - Comprehensive phenotypes of patients with SYNGAP1-related disorder reveals high rates of epilepsy and autism - https://pubmed.ncbi.nlm.nih.gov/38470175/ Pubmed is at 28 (so less than one a week…) https://pubmed.ncbi.nlm.nih.gov/?term=syngap1&filter=years.2025-2025&timeline=expanded&sort=date&sort_order=asc CURE SYNGAP1 CONNECT https://curesyngap1.org/curesyngap1connect/ SHARE BLOOD TO THE SRF BIOBANK AT CB! Read here for more information: https://curesyngap1.org/blog/fueling-research-syngap1-combinedbrain-biorepository-roadshow/ VOLUNTEER Join us: https://curesyngap1.org/volunteer-with-srf/ SOCIAL MATTERS - 4,238 LinkedIn. https://www.linkedin.com/company/curesyngap1/ - 1,400 followers with 575 Videos on YouTube. https://www.youtube.com/@CureSYNGAP1 - 11,302 Twitter https://twitter.com/cureSYNGAP1 - 46k Insta https://www.instagram.com/curesyngap1/ NEWLY DIAGNOSED? New families have resources here! https://syngap.fund/Resources Podcasts, give all of these a five star review! https://cureSYNGAP1.org/SRFApple https://podcasts.apple.com/us/channel/syngap1-podcasts-by-srf/id6464522917 Episode 175 of #Syngap10 #RareDisease #PatientAdvocacy #SYNGAP1 #SynGAP #ProMMiS
We know some of you listen to City Cast Philly (and other podcasts) while you run. Maybe you're running right now! Or maybe you want to start running and even try a race? If so, now's the time to start training for the Philadelphia Marathon (or Half Marathon) later this year. Executive producer Matt Katz sits down with Michelle Quirk – a run coach, podcaster, and primary care doctor at CHOP – to get tips and tricks for moving your running game in Philly to the next level. Get Philly news & events in your inbox with our newsletter: Hey Philly Call or text us: 215-259-8170 We're also on Instagram: @citycastphilly Learn more about the sponsors of this July 15th episode: Rock & Roll Hall of Fame Scribe Video Center Advertise on the podcast or in the newsletter: citycast.fm/advertise Learn more about your ad choices. Visit megaphone.fm/adchoices
Seattle lawyer, Evan Oshan, joins Rafe Foreman to explore his groundbreaking negligence suit against the City of Seattle over the CHOP Zone—where two Black youths were shot, one fatally, amid an “off-limits” protest precinct. Learn how municipal leaders' decision to abandon public safety unleashed chaos, spoliated evidence, and left victims without help, and why Oshan refuses to let this miscarriage of justice go unchallenged. From breaking through governmental immunity to honoring his client's plea for trial, discover what it takes to fight fearlessly for truth and accountability when civic duty fails.
Fennel butter 1 shallot, finely chopped 1 clove garlic, chopped 1 tablespoon olive oil 200ml dry white wine 250g soft butter Large handful fennel herb chopped ( substitute any soft herb like basil, chives, parsley etc)Cook the shallot and garlic in the oil until golden. Add the wine and reduce until none of the liquid remains. Blend with the butter and fennel to a smooth paste. Roll in cling in the shape of a sausage and chill. Can be divided up and frozen in batches.350g fregola ( or substitute orzo pasta) 2 shallots, finely chopped 2 cloves garlic, minced 1 tablespoon olive oil plus more for brushing 200g heritage tomatoes, cut into 2cm chunks 1 yellow courgette 1 green courgette 200ml vegetable stock 1tablespoon balsamic vinegar 75g grated parmesan 50g fennel butter ( or just use regular butter) Chopped parsley, lovage to finishSlice the courgettes in half lengthwise then cut into ½ cm thick strips. Brush with oil and cook on a hot griddle pan to scorch for about 2 minutes each side – season with salt. Chop the courgettes into chunks. Cook the shallot and garlic in the oil until golden then add the tomatoes. Season with salt and pepper and cook for 4 minutes. Add the courgettes and stock, place a lid on top and simmer for 5 minutes. Cook the fregola in boiling salted water for about 7 minutes. Add the balsamic and butter to the courgette mixture and stir until fully incorporated. Drain the fregola well and add to the mixture. Add half the parmesan and herbs and mix well. Spoon into bowls and top with the remaining parmesan.
Text us about COMICS! Or about whatever. It's your life. Here we go, Legion! In honor of the NEW James Gunn Superman movie dropping THIS weekend, we're ranking the most recent 7 Superman movies! Let's break down the previous three Man of Steel performances and see which one is the best of the best. And will Superman 2025 measure up? It's time for real estate tycoons, evil versions with five o'clock shadows, Kryptonite continents, and MAAARRRRTHHHHAAAAAAA! New Episodes Every Week, mostly!Support us on Patreon! Get exclusive content! https://www.patreon.com/legionofcc SUBSCRIBE HERE: https://bit.ly/LegionOCCBrett Garwood - Man Behind The Curtain: https://redbagmedia.com/Our totally rad intro music comes from: Alex at Chop.it.up.productionsListen to our Podcast - Legion of Comic Correction - on all major podcasting platforms!Legion Website: legionofcc.comLCC Facebook: https://www.facebook.com/LegionofCC LCC Instagram: https://www.instagram.com/legionofcc/Support the show
In this episode of Sg2 Perspectives, Jayme Zage, PhD speaks with leaders from the Children's Hospital of Philadelphia (CHOP), Katherine Helbig, MS, LCGC, AVP of Research Strategy and Accelerator Programs, and Dan Fields, JD, SVP and Chief Strategy Officer, about the evolving landscape of cell and gene therapy. They share compelling patient stories and outline the operational and strategic infrastructure needed to deliver these groundbreaking treatments. From CAR T-cell therapies to life-changing gene therapies for chronic conditions, CHOP's commitment to innovation and sustainability offers insights for organizations looking to enter this dynamic space. We are always excited to get ideas and feedback from our listeners. You can reach us at sg2perspectives@sg2.com, or visit the Sg2 company page on LinkedIn.
A new study conducted by a team at Children's Hospital of Philadelphia and published in the Journal of the American Medical Association reveals a deeply troubling reality: children in the United States are facing worse health outcomes than their peers in other high-income nations—across nearly every indicator. Michael Smerconish breaks down the findings with insight, urgency, and a bit of personal reflection. From chronic conditions and gun violence to mental health, poverty, and policy failures, this episode dives deep into why America is falling short. This is the premise for today's Daily Poll Question at Smerconish.com, which asks: Why do U.S. children have comparatively worse health outcomes? Listen here, then vote there!
12 - There is a complete ratcheting up against ICE by the American people. Why? 1205 - Nemours Hospitals joins the list of places to cut back on gender affirming care, but CHOP still offers their services. Why do we still have to suffer from something everyday people know is just a crazy trend! 1220 - Is this mother-daughter tandem offering to pick up your trash in Philadelphia a “scab” move? Your calls. 1235 - Chair of the Republican Committee of Chester County Dr. Raffi Terzian joins us today. How encouraging is it to see that flipping Chester County to red is within striking distance? Why has Chester County been blue in more recent years? What is the disconnect between voters and the elected officials in the county? How can Chester County go red in the upcoming elections? 1250 - Why did Trump pour cold water all over a question about Jeffrey Epstein directed towards Pam Bondi? Why does Pam Bondi feel the need to spin her answer to the question?
12 - There is a complete ratcheting up against ICE by the American people. Why? 1205 - Nemours Hospitals joins the list of places to cut back on gender affirming care, but CHOP still offers their services. Why do we still have to suffer from something everyday people know is just a crazy trend! 1210 - Side - What story would you like to get to the bottom of? 1220 - Is this mother-daughter tandem offering to pick up your trash in Philadelphia a “scab” move? Your calls. 1235 - Chair of the Republican Committee of Chester County Dr. Raffi Terzian joins us today. How encouraging is it to see that flipping Chester County to red is within striking distance? Why has Chester County been blue in more recent years? What is the disconnect between voters and the elected officials in the county? How can Chester County go red in the upcoming elections? 1250 - Why did Trump pour cold water all over a question about Jeffrey Epstein directed towards Pam Bondi? Why does Pam Bondi feel the need to spin her answer to the question? 1 - Continuing with the mysterious messaging from Trump regarding the Jeffrey Epstein case. Why doesn't Trump and the cabinet realize that people really care about this issue? Your calls. 115 - New Jersey is the most moved-out state in the country this year, but what state has the most people coming to town? Is Jersey close to a reckoning? Do their gubernatorial polling numbers indicate that? 120 - Your calls. 135 - Bucks County Sheriff Fred Harran joins the program today. How does he feel about local politicians trying to nationalize and politicize a local sheriff's race? Where is the County Sheriff's office with their ICE certification? What is the point of getting that certification? What can we expect to hear from Fred's podcast in the near future? 150 - Your calls to wrap up the hour. 2 - The duality of Trump: disparaging the Jeffrey Epstein story and also being nominated by Benjamin Netanyahu for the Nobel Peace Prize. 210 - How does this Trump DOJ compare with Biden's? Do people take notice of these dodges from our government? 215 - Dom's Money Melody! 220 - Is the water safe to drink? Can we give the sanitation workers their right to live where they please? 235 - Superman actor Sean Gunn sparks controversy with his thoughts on Superman and immigration. 240 - Your calls. 250 - The Lightning Round!
Eric Topol (00:05):Hello, it's Eric Topol from Ground Truths, and I've got some really exciting stuff to talk to you about today. And it's about the announcement for a new Center for pediatric CRISPR Cures. And I'm delight to introduce doctors Jennifer Doudna and Priscilla Chan. And so, first let me say this is amazing to see this thing going forward. It's an outgrowth of a New England Journal paper and monumental report on CRISPR in May. [See the below post for more context]Let me introduce first, Dr. Doudna. Jennifer is the Li Ka Shing Chancellor's Chair and a Professor in the departments of chemistry and of molecular and cell biology at the University of California Berkeley. She's also the subject of this book, one of my favorite books of all time, the Code Breaker. And as you know, the 2020 Nobel Prize laureate for her work in CRISPR-Cas9 genome editing, and she founded the Innovative Genomics Institute (IGI) back 10 years ago. So Jennifer, welcome.Jennifer Doudna (01:08):Thank you, Eric. Great to be here.Eric Topol (01:10):And now Dr. Priscilla Chan, who is the co-founder of the Chan Zuckerberg Initiative (CZI) that also was started back in 2015. So here we are, a decade later, these two leaders. She is a pediatrician having trained at UCSF and is committed to the initiative which has as its mission statement, “to make it possible to cure, prevent, and manage all diseases in this century.” So today we're going to talk about a step closer to that. Welcome, Priscilla.Priscilla Chan (01:44):Thank you. Thanks for having me.Eric Topol (01:46):Alright, so I thought we'd start off by, how did you two get together? Have you known each other for over this past decade since you both got all your things going?Jennifer Doudna (01:56):Yes, we have. We've known each other for a while. And of course, I've admired the progress at the CZI on fundamental science. I was an advisor very early on and I think actually that's how we got to know each other. Right, Priscilla?Priscilla Chan (02:11):Yeah, that's right. We got to know each other then. And we've been crisscrossing paths. And I personally remember the day you won the Nobel Prize. It was in the heart of the pandemic and a lot of celebrations were happening over Zoom. And I grabbed my then 5-year-old and got onto the UCSF celebration and I was like, look, this is happening. And it was really cool for me and for my daughter.Eric Topol (02:46):Well, it's pretty remarkable convergence leading up to today's announcement, but I know Priscilla, that you've been active in this rare disease space, you've had at CZI a Rare As One Project. Maybe you could tell us a bit about that.Priscilla Chan (03:01):Yeah, so at CZI, we work on basic science research, and I think that often surprises people because they know that I'm a pediatrician. And so, they often think, oh, you must work in healthcare or healthcare delivery. And we've actually chosen very intentionally to work in basic science research. In part because my training as a pediatrician at UCSF. As you both know, UCSF is a tertiary coronary care center where we see very unusual and rare cases of pediatric presentations. And it was there where I learned how little we knew about rare diseases and diseases in general and how powerful patients were. And that research was the pipeline for hope and for new discoveries for these families that often otherwise don't have very much access to treatments or cures. They have a PDF that maybe describes what their child has. And so, I decided to invest in basic science through CZI, but always saw the power of bringing rare disease patient cohorts. One, because if you've ever met a parent of a child with rare disease, they are a force to be reckoned with. Two, they can make research so much better due to their insights as patients and patient advocates. And I think they close the distance between basic science and impact in patients. And so, we've been working on that since 2019 and has been a passion of ours.Eric Topol (04:40):Wow, that's great. Now Jennifer, this IGI that you founded a decade ago, it's doing all kinds of things that are even well beyond rare diseases. We recently spoke, I know on Ground Truths about things as diverse as editing the gut microbiome in asthma and potentially someday Alzheimer's. But here you were very much involved at IGI with the baby KJ Muldoon. Maybe you could take us through this because this is such an extraordinary advance in the whole CRISPR Cures story.Jennifer Doudna (05:18):Yes, Eric. It's a very exciting story and we're very, very proud of the teamwork that went into making it possible to cure baby KJ of his very rare disease. And in brief, the story began back in August of last year when he was born with a metabolic disorder that prevented him from digesting protein, it's called a urea cycle disorder and rare, but extremely severe. And to the point where he was in the ICU and facing a very, very difficult prognosis. And so, fortunately his clinical team at Children's Hospital of Philadelphia (CHOP) reached out to Fyodor Urnov, who is the Director of Translational Medicine at the IGI here in the Bay Area. They teamed up and realized that they could quickly diagnose that child because we had an IRB approved here at the IGI that allowed us to collect patient samples and do diagnosis. So that was done.Jennifer Doudna (06:26):We created an off-the-shelf CRISPR therapy that would be targeted to the exact mutation that caused that young boy's disease. And then we worked with the FDA in Washington to make sure that we could very safely proceed with testing of that therapy initially in the lab and then ultimately in two different animal models. And then we opened a clinical trial that allowed that boy to be enrolled with, of course his parents' approval and for him to be dosed and the result was spectacular. And in fact, he was released from the hospital recently as a happy, healthy child, gaining lots of weight and looking very chunky. So it's really exciting.Eric Topol (07:16):It's so amazing. I don't think people necessarily grasp this. This timeline [see above] that we'll post with this is just mind boggling how you could, as you said Jennifer, in about six months to go from the birth and sequencing through cell specific cultures with the genome mutations through multiple experimental models with non-human primates even, looking at off-target effects, through the multiple FDA reviews and then dosing, cumulatively three dosing to save this baby's life. It really just amazing. Now that is a template. And before we go to this new Center, I just wanted to also mention not just the timeline of compression, which is unimaginable and the partnership that you've had at IGI with I guess Danaher to help manufacture, which is just another part of the story. But also the fact that you're not just even with CRISPR 1.0 as being used in approvals previously for sickle cell and β-thalassemia, but now we're talking about base editing in vivo in the body using mRNA delivery. So maybe you could comment on that, Jennifer.Jennifer Doudna (08:38):Yeah, very good point. So yeah, we used a version of CRISPR that was created by David Liu at the Broad Institute and published and available. And so, it was possible to create that, again, targeted to the exact mutation that caused baby KJ's disease. And fortunately, there was also an off-the-shelf way to deliver it because we had access to lipid nanoparticles that were developed for other purposes including vaccinations. And the type of disease that KJ suffered from is one that is treatable by editing cells in the liver, which is where the lipid nanoparticle naturally goes. So there were definitely some serendipity here, but it was amazing how all of these pieces were available. We just had to pull them together to create this therapy.Eric Topol (09:30):Yeah, no, it is amazing. So that I think is a great substrate for starting a new Center. And so, maybe back to you Priscilla, as to what your vision was when working with Jennifer and IGI to go through with this.Priscilla Chan (09:45):I think the thing that's incredibly exciting, you mentioned that at CZI our mission is to cure, prevent, and manage all disease. And when we talked about this 10 years ago, it felt like this far off idea, but every day it seems closer and closer. And I think the part that's super exciting about this is the direct connection between the basic science that's happening in CRISPR and the molecular and down to the nucleotide understanding of these mutations and the ability to correct them. And I think many of us, our imaginations have included this possibility, but it's very exciting that it has happened with baby KJ and CHOP. And we need to be able to do the work to understand how we can treat more patients this way, how to understand the obstacles, unblock them, streamline the process, bring down the cost, so that we better understand this pathway for treatment, as well as to increasingly democratize access to this type of platform. And so, our hope is to be able to do that. Take the work and inspiration that IGI and the team at CHOP have done and continue to push forward and to look at more cases, look at more organ systems. We're going to be looking in addition to the liver, at the bone marrow and the immune system.Priscilla Chan (11:17):And to be able to really work through more of the steps so that we can bring this to more families and patients.Eric Topol (11:30):Yeah, well it's pretty remarkable because here you have incurable ultra-rare diseases. If you can help these babies, just think of what this could do in a much broader context. I mean there a lot of common diseases have their roots with some of these very rare ones. So how do you see going forward, Jennifer, as to where you UC Berkeley, Gladstone, UCSF. I'm envious of you all up there in Northern California I have to say, will pull this off. How will you get the first similar case to KJ Muldoon going forward?Jennifer Doudna (12:13):Right. Well, IGI is a joint institute, as you probably know, Eric. So we were founded 10 years ago as a joint institute between UC Berkeley and UCSF. And now we have a third campus partner, UC Davis and we have the Gladstone Institute. So we've got an extraordinary group of clinicians and researchers that are coming together for this project and the Center to make it a success. We are building a clinical team at UCSF. We have several extraordinary leaders including Jennifer Puck and Chris Dvorak, and they are both going to be involved in identifying patients that could be enrolled in this program based on their diagnosis. And we will have a clinical advisory group that will help with that as well. So we'll be vetting patients probably right after we announce this, we're going to be looking to start enrolling people who might need this type of help.Eric Topol (13:18):Do you think it's possible to go any faster right now than the six months that it took for KJ?Jennifer Doudna (13:26):I think it could be. And here's the reason. There's a very interesting possibility that because of the type of technology that we're talking about with CRISPR, which fundamentally, and you and I have talked about this previously on your other podcast. But we've talked about the fact that it's a programmable technology and that means that we can change one aspect of it, one piece of it, which is a piece of a molecule called RNA that's able to direct CRISPR to the right sequence where we want to do editing and not change anything else about it. The protein, the CRISPR protein stays the same, the delivery vehicle stays the same, everything else stays the same. And so, we're working right now with FDA to get a platform designation for CRISPR that might allow streamlining of the testing process in some cases. So it'll obviously come down to the details of the disease, but we're hopeful that in the end it will be possible. And Priscilla and I have talked about this too, that as AI continues to advance and we get more and more information about rare diseases, we'll be able to predict accurately the effects of editing. And so, in some cases in the future it may be possible to streamline the testing process even further safely.Eric Topol (14:51):And I also would note, as you both know, well this administration is really keen on genome editing and they've had a joint announcement regarding their support. And in my discussions with the FDA commissioner, this is something they are very excited about. So the timing of the new Center for pediatric CRISPR Cures is aligned with the current administration, which is good to see. It's not always the case. Now going back, Priscilla, to your point that not just for the liver because delivery has been an issue of course, and we're going to try to get after a lot of these really rare diseases, it's going to go beyond there. So this is also an exciting new dimension of the Center, as you said, to go after the bone marrow for hematopoietic cells, perhaps other organs as well.Priscilla Chan (15:42):I mean what the expertise and feasibility, the immune system is going to be the next target. Jennifer Puck has been a pioneer in this work. She's the one who designed the newborn screen that will be the tool that picks up these patients as they are born. And I think the thing that's tremendous is the immune system, first of all is active in many, many diseases, not just these cases of children born with partial or absence of immune systems. And the course right now that these babies are left with is complete isolation and then a very long and arduous course of a bone marrow transplant with high morbidity and mortality. And even if after the transplant you have complications like graft versus host and immunosuppression. And so, the idea of being able to very specifically and with less the conditioning and morbidity and mortality of the treatment, being able to address this is incredible. And the implications for other diseases like blood cancers or other hematopoietic diseases, that's incredible. And that actually has an incredibly broad base of patients that can benefit from the learnings from these babies with severe combined immunodeficiencies.Eric Topol (17:10):Yeah, I think that goes back to a point earlier maybe to amplify in that previous CRISPR generation, it required outside the body work and it was extremely laborious and time consuming and obviously added much more to the expense because of hospitalization time. This is different. This is basically doing this inside the affected patient's body. And that is one of the biggest reasons why this is a big step forward and why we're so fortunate that your Center is moving forward. Maybe before we wrap up, you might want to comment, Jennifer on how you were able to bring in to build this platform, the manufacturing arm of it, because that seems to be yet another dimension that's helpful.Jennifer Doudna (18:01):Indeed, yes. And we were again fortunate with timing because you mentioned briefly that the IGI had set up a program with the Danaher Corporation back in January of last year. We call it our Beacon project. And it's focused on rare disease. And it's a really interesting kind of a unique partnership because Danaher is a manufacturing conglomerate. So they have companies that make molecules, they make proteins, they make RNA molecules, they make delivery molecules. And so, they were excited to be involved with us because they want to be a provider of these types of therapies in the future. And they can see the future of CRISPR is very exciting. It's expanding, growing area. And so, that agreement was in place already when the baby KJ case came to our attention. And so, what we're hoping to do with Danaher is again, work with them and their scientists to continue to ask, how can we reduce the cost of these therapies by reducing the cost of the molecules that are necessary, how to make them efficiently. We already, it's very interesting, Fyodor Urnov has toured their plant in North Dakota recently, and he found in talking to their engineers, there are a number of things that we can already see will be possible to do that are going to make the process of manufacturing these molecules faster and cheaper by a lot.Eric Topol (19:28):Wow.Jennifer Doudna (19:28):So it's a win-win for everybody. And so, we're really excited to do that in the context of this new Center.Eric Topol (19:36):Oh, that's phenomenal because some of these disorders you don't have that much time to work with before they could be brain or organ or vital tissue damage. So that's great to hear that. What you built here is the significance of it can't be under emphasized, I'll say because we have this May report of baby KJ, which could have been a one-off and it could have been years before we saw another cure of an ultra-rare disorder. And what you're doing here is insurance against that. You're going to have many more cracks at this. And I think this is the excitement about having a new dedicated Center. So just in closing, maybe some remarks from you Priscilla.Priscilla Chan (20:24):I just want to emphasize one point that's really exciting as we talk about these ultra-rare cases that they're often like one in a million. All these learnings actually help maximize the impact of lots of research across the sector that impacts actually everyone's health. And so, our learnings here from these patients that have very significant presentations that really can stand to benefit from any treatment is hopefully paving the way for many, many more of us to be able to live healthier, higher quality lives through basic science.Eric Topol (21:13):And over to you, Jennifer.Jennifer Doudna (21:15):Couldn't agree more. It's a really interesting moment. I think what we hope we are, is we're at sort of an inflection point where, as I mentioned earlier, all the pieces are in place to do this kind of therapeutic and we just need a team that will focus on doing it and pulling it together. And also learning from that process so that as Priscilla just said, we are ultimately able to use the same strategy for other diseases and potentially for diseases that affect lots of people. So it's exciting.Eric Topol (21:46):For sure. Now, if I could just sum up, this is now a decade past the origination of your work of CRISPR and how already at the first decade culminated in sickle cell disease treatment and β-thalassemia. Now we're into the second decade of CRISPR. And look what we've seen, something that was unimaginable until it actually happened and was reported just a little over a month ago. Now going back to Priscilla's point, we're talking about thousands of different rare Mendelian genomic disorders, thousands of them. And if you add them all up of rare diseases, we're talking about hundreds of millions of people affected around the world. So this is a foray into something much bigger, no less the fact that some of these rare mutations are shared by common diseases and approaches. So this really big stuff, congratulations to both of you and your organizations, the Innovative Genomics Institute and the Chan Zuckerberg Initiative for taking this on. We'll be following it with very deep interest, thank you.****************************************************Thanks for listening, reading and subscribing to Ground Truths.If you found this interesting PLEASE share it!That makes the work involved in putting these together especially worthwhile.Thanks to Scripps Research, and my producer, Jessica Nguyen, and Sinjun Balabanoff for video/audio support.All content on Ground Truths—its newsletters, analyses, and podcasts, are free, open-access.Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don't hesitate to post comments and give me feedback. Let me know topics that you would like to see covered.Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. Get full access to Ground Truths at erictopol.substack.com/subscribe
July 7, 2025 Week 28 ADAMS CAMP https://curesyngap1.org/podcasts/syngap10/adams-camp-is-amazing-so-are-compression-vests-s10e110/ CENSUS & WHY WE WILL SEE MORE PATIENTS AAP recommends Whole Exome as a first line test for GDD/ID. https://www.linkedin.com/posts/ambry-genetics_exome-cns-patientforlife-activity-7343354049586466816-Jbq_ SYNGAP1 Census 2Q25 +55; new total 1,636, but we need to look at country by country to appreciate how low that is. https://curesyngap1.org/census/ https://docs.google.com/spreadsheets/d/1oJwMysR2wyTxe91zLlKJglNa0NySPxkBF0PRiV6mBmM/edit?gid=0#gid=0 First patients from Bulgaria, Pakistan, Paraguay, and Uruguay. US, Germany & France growing but UK standing still? WARRIORS & PARENT STORIES https://curesyngap1.org/syngap-warriors/ Charlotte - Charlotte is 18 months old - diagnosed on May, 2025, just over a month ago. Already been to UNC and planning to go to CHOP. 17I thought it was worth noting the fast action this family is taking. Martina - First patient from Uruguay. SYNGAP1 Stories episode 35 Nicole Ciccone, son Jackson (from Georgia, near Atlanta) cureSYNGAP1.org/Stories IMPORTANT SRF POSTS Webinar #108 - Repurposing opportunity for SYNGAP1 Specific nonsense mutations with Dr Bruce Bloom, Founder of Fortuity Pharma is up https://curesyngap1.org/resources/webinars/webinar-108-fortuity-pharma-repurposing-nonsense-mutations/ VOLUNTEER SHOUT OUT Suzanne Vreeland Jones for helping get the resource mobilization group organized in general and attending so many meetings, applying for grants, organizing the drive, and creating a fundraising plan for the rest of the year. And just generally caring about what's going on and what needs to get done. She's also the board chair and organizes all of that every 6 weeks. Then there's so much she's done and is doing for the conference so far as it is in Atlanta. We can trust it will be a nice event with her helping and being so close. CONFERENCE - DECEMBER 4th & 5th Hotel has been selected for Atlanta - Georgia Tech Hotel & Conference Center; see cureSYNGAP1.org/Atlanta FUNDRAISING - SIBLINGS ARE THE NEXT GEN OF SRF Fundraiser - LOVING ON LIAM - Emma's Hope for a SYNGAP1 Cure; fundraiser by Liam's sister Emma, who is promising a handmade pin for $5+ donations and over $100 a front flip off the diving board - cureSYNGAP1.org/Liam raised $2,370 in June! WEBINAR #108 - Repurposing opportunity for SYNGAP1 nonsense mutations with Dr Bruce E. Bloom from Fortuity Pharma is up on YouTube https://youtu.be/4nqCLwuikIE?si=xWtbw-5OP_uMBwK5 and our website cureSYNGAP1.org/Webinars PRESS RELEASE https://curesyngap1.org/blog/prof-kristian-stromgaard-awarded-cure-syngap1-grant-research-biomolecular-condensates-pr40/ WHY OUR RESEARCH MATTERS Bowie Lab Talk on Glutamatergic Neurons. We learn about Intelligence from studying ID. https://www.youtube.com/watch?v=sfcN2BuZOJw NUMBERS PUBMED 334, 26, so -1 vs. weeks. Follow on Youtube and LinkedIn, they matter. https://www.linkedin.com/company/curesyngap1/ 4,221 https://www.youtube.com/@CureSYNGAP1 1,390 #S10e173 CORRECTION I credited the Sprint blog to "probably Ed". Thanks, but that one was coordinated by Jo Ashline. NICOLE'S POST I hate Autism Awareness Month. It stirs up so many emotions- anger, grief, and frustration for everything autism has taken from my son. Dear Syngap, It's me again. You'd think after all this time, we'd have some kind of understanding. But we don't. We never will. You barged into our lives uninvited, turned our world upside down, and refused to leave. You've taught me lessons I never asked for, dragged us down roads we never wanted to travel. You've humbled me, broken me, enraged me. I've cried because of you. Screamed into the silence. Begged the universe for answers it refuses to give. I've celebrated victories that should have been simple, ordinary things—but with you lurking in the shadows, nothing is ever simple. If I'm being honest, I hate you. I hate what you've done to my son. I hate that you've taken things from him that should have been his without question—his voice, his strength, his ease of movement, his peace. One day, he climbs like he was born to conquer mountains. The next, he struggles to take a step. You're a thief, Syngap. You steal his vision, rob him of his muscle tone, drain his energy until even smiling feels like work. You wrap yourself around his body, his mind, his very existence, and no matter how hard I fight, you never let go. You make him miserable. And I hate you for it. You turn his nights into a battlefield, his sleep stolen by seizures, restlessness, and the chaos you planted in his brain. You keep his words locked inside, hidden in a place I can't reach. And God, how I wish I could reach them. How I wish I could hear his thoughts, understand the words he wants so badly to say. Instead, I watch. I listen. I hold him when the frustration turns to tears, when his body betrays him, when he fights a battle most will never see. People don't see what I see. They don't hear the cries in the middle of the night or witness the exhaustion in his body. They don't see the war raging inside him. And me? I've been called crazy, overprotective, dramatic. But I don't care. I'll wear those labels like armor. Because as long as my son is fighting, I will fight harder. You tried to take so much from us. You tried to steal my marriage, tried to break my family apart, tried to strip away our joy. You've knocked us down, over and over again. But listen to me, Syngap: you will never have us. And here's the strangest thing. For all the hell you've put us through, you've also given me things I never expected. You've made me stronger than I ever thought possible. You've forced me to fight with a fierceness I didn't know I had. You've shown me how to love deeper, to celebrate what others overlook, to appreciate moments most take for granted. You take and you take—but somehow, you also build. You break, yet somehow, you make us unbreakable. But hear me loud and clear: you don't win. Tomorrow, my son will wake up, and despite you, he will rise. He will smile. He will fight. He will accomplish things you never thought he could. And I? I'll be there, standing beside him, fighting for him, daring you to try and stop us. You don't get the final say, Syngap. Not today. Not ever. My son is more than you. And you have underestimated his mother. Sincerely, A Syngap Momma
Text us about COMICS! Or about whatever. It's your life. It's time to rank the MCU Phase 3! Let's talk about Avengers Lite, planetary affairs, some REAL good Spider-Man, and the best team-up superhero movie TO DATE! One, two, three, our opinions!New Episodes Every Week, mostly!Support us on Patreon! Get exclusive content! https://www.patreon.com/legionofcc SUBSCRIBE HERE: https://bit.ly/LegionOCCBrett Garwood - Man Behind The Curtain: https://redbagmedia.com/Our totally rad intro music comes from: Alex at Chop.it.up.productionsListen to our Podcast - Legion of Comic Correction - on all major podcasting platforms!Legion Website: legionofcc.comLCC Facebook: https://www.facebook.com/LegionofCC LCC Instagram: https://www.instagram.com/legionofcc/Support the show
Tarik is a veteran independent professional wrestler from Ontario, Canada. He has wrestled all over the country and been in the ring with some of the best pro wrestlers of the modern era. He is known as "Mr. Punch, Kick, Chop." In this episode, Cody Deaner and Tarik explore the idea of how important it is to "Pay Your Dues." Not only in the world of professional wrestling... but also in life. Support Tarik by following him on Instagram: http://instagram.com/punchkickchop_tarik Please support our sponsors at: Rest When Dead Clothing - http://restwhendead.ca CEO Fit Supplements - http://ceofit.ca Support this show: Join the Patreon: http://patreon.com/codydeaner To learn more about Cody's wrestling career and to book him, visit http://CodyDeaner.com To learn more about Cody's speaking career and to book him, visit http://ChrisGraySpeaks.com
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"The higher we go, the more negative sentiment gets," says Eddie Ghabour. He considers the recovery off April lows the "most hated" bull rally he's seen. Eddie still expects that rally to continue in what he sees as a "non-recessionary environment" even if seasonal volatility emerges. Small caps are among the groups he expects to rally into the back half of the year.======== Schwab Network ========Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about
“Stop the Chop” exists to eliminate non-essential helicopters from the skies above New York City – because – according to the "Stop the Chop" website: “Tourist, charter and commuter helicopter flights dramatically reduce the quality of life for millions of people in the metropolitan area. They pollute our environment, pose significant safety risks, harm our children, and make us miserable”It was a hot, second day of summer afternoon in Riverside Park – at the “You've Got Mail” promenade and garden. We sat on a bench and talked with our UWS neighbors about their concerns and questions regarding the Helicopter racket that invades our peaceful moments.Two experts, on the effects of the copter cacophony on our health and enjoyment of the our city parks, joined us -- Melissa Elstein and Ken Coughlin; both long-time NYC community organizers and environmental activists. Melissa was recently on BCR program #221 talking about “Love Your Street Tree Day” sponsored by the “West 80s Neighborhood Association” Hosted on Acast. See acast.com/privacy for more information.
Adam shares his travel troubles to New York before he and Dr. Drew reflect on the lack of cultural awareness in their childhood, especially in media portrayals of the Middle East. They debate whether more government spending, like LA's proposed parcel tax, actually solves problems. The show ends with Adam's thoughts on Drew's new NYC apartment.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Intro - Sam Welcome back to another episode of Let's Go Hunt! - Now with 100% less weeb: Vince H, restarting construction on that ark Mike Gonçalves, who is attending the conference of the “Part-Timers Podcast Guild” Dave Packard, whose pumped And Sam Alexander, Around the Campfire: We are lost. Not much at all. Don't burn yourself! Eventual Ad Slot Personal Gear Chat and Updates: Mike I went on a gobble hunt Dave Crawfish Etouffee https://www.youtube.com/watch?v=0cd-vcgWTYg Colorado Primary draw results Getting into elk shape Sam Another long ass roadtrip and Yellerrock in the books. Turns out it was Memorial Day. Yeaaaaaaah. Vince Done did my controlled hunt application It did awesome things with my minivan News and World Events Spotlighting With Dave: What are some other uses for thermals? Subsonic 22LR: so many ammo options, so what's the difference? What the Rut is going on here? or The Otter Creek Labs Polonium 30. What's it good for? Reviews: Operation Shameless Bribery Gideon Optics affiliate coupon code: MOIST Camorado affiliate code: LETSGOHUNT Outro - Vince Support the sport and take a buddy hunting! If you like that buddy, tell them about our show! If you don't, tell him his mom spearfishes for pigeon. Hit us up at lghpodcast.com. Thanks for listening and Let's Go Hunt! EMAIL: contact@lghpodcast.com Let's Go Hunt Archives - Firearms Radio Network Recipes: CRAWFISH ÉTOUFFÉE 2 Onions 2 Sticks of Celery 1 Green Bell Pepper 1 Red Bell Pepper 1 Bunch Green Onions 4 Cloves of Garlic 2 Sticks of Butter 1 Tablespoon Cajun or Creole Seasoning 1/4 Teaspoon Cayenne Pepper 1/4 Teaspoon of Salt 1/3 Cup of Flour 2 lbs Louisiana Crawfish 2 Cups of Hot Water (Add more if desired) Start out by heating a Pot or Large Pan to a Medium/Low heat. Chop the Onion, Celery, Red Bell Pepper, Green Bell Pepper, and Green Onions. Drop two Sticks of Butter into your hot pot and melt completely. Add the chopped vegetables to the pot and raise burner to a medium. Add the Cajun Seasoning, Cayenne Pepper, and Salt. Sauté for about 20 minutes. Meanwhile chop the four cloves of Garlic. After 20 minuets of sautéing, add the garlic and sauté for another 10 minutes. After 10 more minuets of sautéing, push the vegetables to one side of the pot, add the 1/3 cup of flour and blend into the butter. Once the flour is mixed in well, stir everything altogether. Sauté for another 30 minutes. Be very cautious during this time. If fire seems a little high, lower it. Around this time you want to begin cooking some rice. With about 3 minutes left of sautéing, begin heating 2 cups of water in the microwave. Add a little bit of the hot water to the pot, and stir until it's a creamy mixture. Add the Crawfish and rest of the hot water to the pot. Blend evenly. Raise the heat to where you see a slight boil. Cover, and lower to a simmering heat. Cook for about 15-20 minutes. If you feel as though you would like a thinner sauce, just add a little more water. However, taste to see if you need more seasoning. Enjoy Dat!
Sugar Ray and Barenaked Ladies lead singers, Mark McGrath and Ed Robertson, swing by my kitchen to discuss the music industry, how their songs affected my life, and getting older. I make ‘em Chinese Chicken (of course) and we ALL sing One Week. Because, you have to. Catch them on tour TOGETHER this summer… Last Summer on Earth Tour - https://www.barenakedladies.com/tour-2 Follow Mark McGrath: https://www.instagram.com/therealmarkmcgrath Follow Ed Robertson: https://www.instagram.com/barenakedladiesmusic SUBSCRIBE so you never miss a video https://bit.ly/3DC1ICg Stream LUCKY on Netflix https://www.netflix.com/title/81713944 PERMISSION TO PARTY WORLD TOUR is on sale now: http://www.bertbertbert.com/tour For all things BERTY BOY PRODUCTIONS: https://bertyboyproductions.com For MERCH: https://store.bertbertbert.com/ Follow Me! Facebook: http://www.Facebook.com/BertKreischer Instagram: http://www.Instagram.com/bertkreischer YouTube: http://www.YouTube.com/user/Akreischer TikTok: http://www.TikTok.com/@bertkreischer Threads: https://www.threads.net/@bertkreischer X: http://www.Twitter.com/bertkreischer Text Me: https://my.community.com/bertkreischerDRUNKEN NOODLES W/ CHINESE CHICKENDrunken Noodles:Sauce:* 3 TBS oyster sauce* 2 TBS light soy sauce* 2 TBS dark soy sauce* 1 TBS rice wine vinegar* ½ TBS fish sauce* 1 TBS brown sugar* 2 TBS waterStir-Fry:* 7 ounces dried wide rice noodles* 1 TBS sesame oil* 1 brown onion* 1 TBS grated garlic* 1 carrot, julienned* 1 bunch Bok choy, chopped* 4 scallion stems, sliced* 1 firmly packed cup basil leaves* Chili oil * Crushed roasted peanuts1. Mix together ingredients for sauce.2. Cook rice noodles, then rinse with cold water before draining.3. Heat sesame oil in pan. Add onion and garlic. Add carrot, Bok choy, spring onion, noodles, and stir-fry sauce. Toss well until combined. Remove and serve with basil leaves, topping with chili oil and crushed peanuts.Yu Xiang ChickenChicken Marinade: * ½ tsp kosher salt* 3 tsp potato starch* 4 tsp Rice Wine* 2 TBS light soy sauce* 1 tsp sesame oilSauce: * 2 tsp potato starch* 2 TBS white sugar* Salt* ¼ tsp light soy sauce* 4 TBS Rice Wine* 2 TBS Chinkiang vinegar* 1 tsp dark soy sauce* 2 tsp sesame oil* 2 tsp pure chili oil* ½ cup & 4 TBS waterStir-Fry:* ¼ cup cloud ear mushrooms* ½ cup peanut oil* 4-6 TBS chopped pickled red chilis* 2 spring onions, chopped, white and green parts separated* 4 TBS minced ginger* 12 garlic cloves, minced* 1-10 fresh red chilis * 6-20 dried red chilis, snipped into ½” pieces* ½ cup sliced bamboo shoots1. Slice chicken into thin strips. Combine chicken with salt, potato starch, rice wine, light soy sauce, sesame oil, mixing well, then let marinate.2. Combine all sauce ingredients to make sauce3. Chop spring onion, ginger, garlic, fresh red chilies, and snip the dried red chilis into ½” pieces. Drain and rinse bamboo shoots.4. Bring pot of water to a boil and add sliced mushrooms and bamboo shoots boiling for 1-2 minutes then drain in fine mesh strainer and rinse with cold water.5. Heat peanut oil over high heat then add marinated chicken, stir-frying for 40 seconds. Transfer to strainer and let excess oil drip back into wok. Remove all but 3 TBS of oil from wok.6. Heat oil in wok and add pickled red chilis. Then add spring onion white and light green parts, ginger and garlic. Add fresh and dried chilies cooking for 1 minute, then add sliced mushrooms and bamboo shoots.7. Add chicken and sauce into wok. Serve and garnish with dark green parts of spring onion. Learn more about your ad choices. Visit megaphone.fm/adchoices
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