Podcasts about Chop

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Latest podcast episodes about Chop

Legion of Comic Correction
EP 211 Does Daredevil Born Again Beat Netflix?

Legion of Comic Correction

Play Episode Listen Later Jul 18, 2025 49:19


Text us about COMICS! Or about whatever. It's your life. We've been WAITING for this episode, Legion!  Listen to our no-nonsense, spoiler-filled review of the MCU's Daredevil: Born Again season one!  It's all about no more Daredevil, Kingpin eating his way to mayor, teeth as a registered weapon, and Frank being Frank in all his Punisher GLORY!  Let's talk The Man Without Fear!New Episodes Every Week, mostly!Support us on Patreon! Get exclusive content! https://www.patreon.com/legionofcc SUBSCRIBE HERE: https://bit.ly/LegionOCCBrett Garwood - Man Behind The Curtain: https://redbagmedia.com/Our totally rad intro music comes from: Alex at Chop.it.up.productionsListen to our Podcast - Legion of Comic Correction - on all major podcasting platforms!Legion Website: legionofcc.comLCC Facebook: https://www.facebook.com/LegionofCC LCC Instagram: https://www.instagram.com/legionofcc/Support the show

Slacker & Steve
The wedding day hair chop

Slacker & Steve

Play Episode Listen Later Jul 17, 2025 4:58


A bride is going viral for chopping off a lot of her hair in between her wedding ceremony and her reception. Are you as upset about this as Slacker is?

SynGAP10 weekly 10 minute updates on SYNGAP1 (video)
Global Overview of SYNGAP1 Natural History Studies - Support the SYNGAP1 #ProMMiS – #S10e175

SynGAP10 weekly 10 minute updates on SYNGAP1 (video)

Play Episode Listen Later Jul 17, 2025 17:01


July 16, 2025. Week 29. What is a natural history study (NHS)?  And why do we care? We care because we haven't done this before, heal those born with disease. Natural history studies, which examine the progression of a disease over time, can be either retrospective or prospective. Retrospective studies analyze existing data, like medical records, while prospective studies collect new data over time. Both types are valuable for understanding a disease's course and informing research and treatment strategies. ⁠NHS are critical for clinical trial design.  Size and Quality matter.  Validated scales are better than PROs regardless of what the current rhetoric is. What's going on now? USA - https://curesyngap1.org/resources/studies/syngap1-ProMMiS/ - 135+ over three sites, some with FOUR visits, and counting - Adding GCP - Collaborating with world class institutions and excellent clinicians at Stanford, Children's Colorado and, of course, CHOP. USA - https://Citizen.Health/partners/srf has almost 300 patients! Retrospective Health Data. USA - https://rare-x.org/syngap1/ is where we collect PROs. Australia - Dr. Sheffer is running a study, talk to her or Dani. Latin America - SYNGAP1 Argentina with others joining. Europe - https://www.patre.info/syngap1/  Key takeaways for Industry SYNGAP1 is well positioned to work with… Vlasskamp and Wiltrout are published, Citizen Health is growing & ProMMiS is truly exceptional – and growing, and Rare-X is collecting eight key PROs.   Additionally, there are significant international efforts in Australia, Latin America & Europe. Census: https://curesyngap1.org/blog/syngap1-census-2025-update-55-in-q2-2025-total-1636/  If you are in industry and thinking about starting another NHS for your asset, please don't.  Please instead partner with existing PAGs and NHS studies in your key geographies to move faster, have bigger N and not waste precious patients time, we need to accelerate drug development not slow it down by diluting patients and clinicians between too many studies. Baseline papers on SYNGAP1: 1998 - Huganir - SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family - https://pubmed.ncbi.nlm.nih.gov/9581761/ 2009 - Michaud - Mutations in SYNGAP1 in autosomal nonsyndromic mental retardation - https://pubmed.ncbi.nlm.nih.gov/19196676/ 2013 - Carvill - Targeted resequencing in epileptic encephalopathies identifies de novo mutations in CHD2 and SYNGAP1 - https://pubmed.ncbi.nlm.nih.gov/23708187/ 2019 - Vlasskamp - SYNGAP1 encephalopathy: A distinctive generalized developmental and epileptic encephalopathy - https://pubmed.ncbi.nlm.nih.gov/30541864/ 2023 - Rong - Adult Phenotype of SYNGAP1-DEE - https://pubmed.ncbi.nlm.nih.gov/38045990/ 2024 - Wiltrout - Comprehensive phenotypes of patients with SYNGAP1-related disorder reveals high rates of epilepsy and autism - https://pubmed.ncbi.nlm.nih.gov/38470175/ Pubmed is at 28 (so less than one a week…) https://pubmed.ncbi.nlm.nih.gov/?term=syngap1&filter=years.2025-2025&timeline=expanded&sort=date&sort_order=asc   CURE SYNGAP1 CONNECT https://curesyngap1.org/curesyngap1connect/   SHARE BLOOD TO THE SRF BIOBANK AT CB! Read here for more information: https://curesyngap1.org/blog/fueling-research-syngap1-combinedbrain-biorepository-roadshow/    VOLUNTEER  Join us: https://curesyngap1.org/volunteer-with-srf/    SOCIAL MATTERS - 4,238 LinkedIn.  https://www.linkedin.com/company/curesyngap1/  - 1,400 followers with 575 Videos on YouTube.  https://www.youtube.com/@CureSYNGAP1    - 11,302 Twitter https://twitter.com/cureSYNGAP1  - 46k Insta https://www.instagram.com/curesyngap1/    NEWLY DIAGNOSED? New families have resources here! https://syngap.fund/Resources      Podcasts, give all of these a five star review! https://cureSYNGAP1.org/SRFApple   https://podcasts.apple.com/us/channel/syngap1-podcasts-by-srf/id6464522917    Episode 175 of #Syngap10  #RareDisease #PatientAdvocacy #SYNGAP1 #SynGAP #ProMMiS

City Cast Philly
Your Guide to Running in Philly

City Cast Philly

Play Episode Listen Later Jul 15, 2025 24:46


We know some of you listen to City Cast Philly (and other podcasts) while you run. Maybe you're running right now!  Or maybe you want to start running and even try a race? If so, now's the time to start training for the Philadelphia Marathon (or Half Marathon) later this year. Executive producer Matt Katz sits down with Michelle Quirk – a run coach, podcaster, and primary care doctor at CHOP – to get tips and tricks for moving your running game in Philly to the next level.  Get Philly news & events in your inbox with our newsletter: Hey Philly Call or text us: 215-259-8170 We're also on Instagram: @citycastphilly Learn more about the sponsors of this July 15th episode: Rock & Roll Hall of Fame Scribe Video Center Advertise on the podcast or in the newsletter: citycast.fm/advertise Learn more about your ad choices. Visit megaphone.fm/adchoices

The Trial Lawyers College Podcast
Justice in CHOP with Evan Oshan

The Trial Lawyers College Podcast

Play Episode Listen Later Jul 14, 2025 28:27


Seattle lawyer, Evan Oshan, joins Rafe Foreman to explore his groundbreaking negligence suit against the City of Seattle over the CHOP Zone—where two Black youths were shot, one fatally, amid an “off-limits” protest precinct. Learn how municipal leaders' decision to abandon public safety unleashed chaos, spoliated evidence, and left victims without help, and why Oshan refuses to let this miscarriage of justice go unchallenged. From breaking through governmental immunity to honoring his client's plea for trial, discover what it takes to fight fearlessly for truth and accountability when civic duty fails.

Cooking with Paula McIntyre
Fregola With Grilled Courgettes, Tomatoes And Fennel Butter

Cooking with Paula McIntyre

Play Episode Listen Later Jul 12, 2025 9:14


Fennel butter 1 shallot, finely chopped 1 clove garlic, chopped 1 tablespoon olive oil 200ml dry white wine 250g soft butter Large handful fennel herb chopped ( substitute any soft herb like basil, chives, parsley etc)Cook the shallot and garlic in the oil until golden. Add the wine and reduce until none of the liquid remains. Blend with the butter and fennel to a smooth paste. Roll in cling in the shape of a sausage and chill. Can be divided up and frozen in batches.350g fregola ( or substitute orzo pasta) 2 shallots, finely chopped 2 cloves garlic, minced 1 tablespoon olive oil plus more for brushing 200g heritage tomatoes, cut into 2cm chunks 1 yellow courgette 1 green courgette 200ml vegetable stock 1tablespoon balsamic vinegar 75g grated parmesan 50g fennel butter ( or just use regular butter) Chopped parsley, lovage to finishSlice the courgettes in half lengthwise then cut into ½ cm thick strips. Brush with oil and cook on a hot griddle pan to scorch for about 2 minutes each side – season with salt. Chop the courgettes into chunks. Cook the shallot and garlic in the oil until golden then add the tomatoes. Season with salt and pepper and cook for 4 minutes. Add the courgettes and stock, place a lid on top and simmer for 5 minutes. Cook the fregola in boiling salted water for about 7 minutes. Add the balsamic and butter to the courgette mixture and stir until fully incorporated. Drain the fregola well and add to the mixture. Add half the parmesan and herbs and mix well. Spoon into bowls and top with the remaining parmesan.

Legion of Comic Correction
EP 210 Was Superman ALWAYS Super?

Legion of Comic Correction

Play Episode Listen Later Jul 11, 2025 53:49


Text us about COMICS! Or about whatever. It's your life. Here we go, Legion! In honor of the NEW James Gunn Superman movie dropping THIS weekend, we're ranking the most recent 7 Superman movies! Let's break down the previous three Man of Steel performances and see which one is the best of the best. And will Superman 2025 measure up? It's time for real estate tycoons, evil versions with five o'clock shadows, Kryptonite continents, and MAAARRRRTHHHHAAAAAAA! New Episodes Every Week, mostly!Support us on Patreon! Get exclusive content! https://www.patreon.com/legionofcc SUBSCRIBE HERE: https://bit.ly/LegionOCCBrett Garwood - Man Behind The Curtain: https://redbagmedia.com/Our totally rad intro music comes from: Alex at Chop.it.up.productionsListen to our Podcast - Legion of Comic Correction - on all major podcasting platforms!Legion Website: legionofcc.comLCC Facebook: https://www.facebook.com/LegionofCC LCC Instagram: https://www.instagram.com/legionofcc/Support the show

Sg2 Perspectives
Cell and Gene Therapy in Practice

Sg2 Perspectives

Play Episode Listen Later Jul 9, 2025 20:03


In this episode of Sg2 Perspectives, Jayme Zage, PhD speaks with leaders from the Children's Hospital of Philadelphia (CHOP), Katherine Helbig, MS, LCGC, AVP of Research Strategy and Accelerator Programs, and Dan Fields, JD, SVP and Chief Strategy Officer, about the evolving landscape of cell and gene therapy. They share compelling patient stories and outline the operational and strategic infrastructure needed to deliver these groundbreaking treatments. From CAR T-cell therapies to life-changing gene therapies for chronic conditions, CHOP's commitment to innovation and sustainability offers insights for organizations looking to enter this dynamic space.   We are always excited to get ideas and feedback from our listeners. You can reach us at sg2perspectives@sg2.com, or visit the Sg2 company page on LinkedIn.

The Smerconish Podcast
U.S. Kids Are Twice as Likely to Die—The Devastating Data No One's Talking About

The Smerconish Podcast

Play Episode Listen Later Jul 8, 2025 14:59


A new study conducted by a team at Children's Hospital of Philadelphia and published in the Journal of the American Medical Association reveals a deeply troubling reality: children in the United States are facing worse health outcomes than their peers in other high-income nations—across nearly every indicator. Michael Smerconish breaks down the findings with insight, urgency, and a bit of personal reflection. From chronic conditions and gun violence to mental health, poverty, and policy failures, this episode dives deep into why America is falling short. This is the premise for today's Daily Poll Question at Smerconish.com, which asks: Why do U.S. children have comparatively worse health outcomes? Listen here, then vote there!

The Dom Giordano Program
Down to the Nitty-Gritty (Full Show)

The Dom Giordano Program

Play Episode Listen Later Jul 8, 2025 140:18


12 - There is a complete ratcheting up against ICE by the American people. Why? 1205 - Nemours Hospitals joins the list of places to cut back on gender affirming care, but CHOP still offers their services. Why do we still have to suffer from something everyday people know is just a crazy trend! 1210 - Side - What story would you like to get to the bottom of? 1220 - Is this mother-daughter tandem offering to pick up your trash in Philadelphia a “scab” move? Your calls. 1235 - Chair of the Republican Committee of Chester County Dr. Raffi Terzian joins us today. How encouraging is it to see that flipping Chester County to red is within striking distance? Why has Chester County been blue in more recent years? What is the disconnect between voters and the elected officials in the county? How can Chester County go red in the upcoming elections? 1250 - Why did Trump pour cold water all over a question about Jeffrey Epstein directed towards Pam Bondi? Why does Pam Bondi feel the need to spin her answer to the question? 1 - Continuing with the mysterious messaging from Trump regarding the Jeffrey Epstein case. Why doesn't Trump and the cabinet realize that people really care about this issue? Your calls. 115 - New Jersey is the most moved-out state in the country this year, but what state has the most people coming to town? Is Jersey close to a reckoning? Do their gubernatorial polling numbers indicate that? 120 - Your calls. 135 - Bucks County Sheriff Fred Harran joins the program today. How does he feel about local politicians trying to nationalize and politicize a local sheriff's race? Where is the County Sheriff's office with their ICE certification? What is the point of getting that certification? What can we expect to hear from Fred's podcast in the near future? 150 - Your calls to wrap up the hour. 2 - The duality of Trump: disparaging the Jeffrey Epstein story and also being nominated by Benjamin Netanyahu for the Nobel Peace Prize. 210 - How does this Trump DOJ compare with Biden's? Do people take notice of these dodges from our government? 215 - Dom's Money Melody! 220 - Is the water safe to drink? Can we give the sanitation workers their right to live where they please? 235 - Superman actor Sean Gunn sparks controversy with his thoughts on Superman and immigration. 240 - Your calls. 250 - The Lightning Round!

The Dom Giordano Program
There's Always Scabbing in Philadelphia

The Dom Giordano Program

Play Episode Listen Later Jul 8, 2025 46:44


12 - There is a complete ratcheting up against ICE by the American people. Why? 1205 - Nemours Hospitals joins the list of places to cut back on gender affirming care, but CHOP still offers their services. Why do we still have to suffer from something everyday people know is just a crazy trend! 1220 - Is this mother-daughter tandem offering to pick up your trash in Philadelphia a “scab” move? Your calls. 1235 - Chair of the Republican Committee of Chester County Dr. Raffi Terzian joins us today. How encouraging is it to see that flipping Chester County to red is within striking distance? Why has Chester County been blue in more recent years? What is the disconnect between voters and the elected officials in the county? How can Chester County go red in the upcoming elections? 1250 - Why did Trump pour cold water all over a question about Jeffrey Epstein directed towards Pam Bondi? Why does Pam Bondi feel the need to spin her answer to the question?

Ground Truths
New Center for Pediatric CRISPR Cures

Ground Truths

Play Episode Listen Later Jul 8, 2025 23:08


Eric Topol (00:05):Hello, it's Eric Topol from Ground Truths, and I've got some really exciting stuff to talk to you about today. And it's about the announcement for a new Center for pediatric CRISPR Cures. And I'm delight to introduce doctors Jennifer Doudna and Priscilla Chan. And so, first let me say this is amazing to see this thing going forward. It's an outgrowth of a New England Journal paper and monumental report on CRISPR in May. [See the below post for more context]Let me introduce first, Dr. Doudna. Jennifer is the Li Ka Shing Chancellor's Chair and a Professor in the departments of chemistry and of molecular and cell biology at the University of California Berkeley. She's also the subject of this book, one of my favorite books of all time, the Code Breaker. And as you know, the 2020 Nobel Prize laureate for her work in CRISPR-Cas9 genome editing, and she founded the Innovative Genomics Institute (IGI) back 10 years ago. So Jennifer, welcome.Jennifer Doudna (01:08):Thank you, Eric. Great to be here.Eric Topol (01:10):And now Dr. Priscilla Chan, who is the co-founder of the Chan Zuckerberg Initiative (CZI) that also was started back in 2015. So here we are, a decade later, these two leaders. She is a pediatrician having trained at UCSF and is committed to the initiative which has as its mission statement, “to make it possible to cure, prevent, and manage all diseases in this century.” So today we're going to talk about a step closer to that. Welcome, Priscilla.Priscilla Chan (01:44):Thank you. Thanks for having me.Eric Topol (01:46):Alright, so I thought we'd start off by, how did you two get together? Have you known each other for over this past decade since you both got all your things going?Jennifer Doudna (01:56):Yes, we have. We've known each other for a while. And of course, I've admired the progress at the CZI on fundamental science. I was an advisor very early on and I think actually that's how we got to know each other. Right, Priscilla?Priscilla Chan (02:11):Yeah, that's right. We got to know each other then. And we've been crisscrossing paths. And I personally remember the day you won the Nobel Prize. It was in the heart of the pandemic and a lot of celebrations were happening over Zoom. And I grabbed my then 5-year-old and got onto the UCSF celebration and I was like, look, this is happening. And it was really cool for me and for my daughter.Eric Topol (02:46):Well, it's pretty remarkable convergence leading up to today's announcement, but I know Priscilla, that you've been active in this rare disease space, you've had at CZI a Rare As One Project. Maybe you could tell us a bit about that.Priscilla Chan (03:01):Yeah, so at CZI, we work on basic science research, and I think that often surprises people because they know that I'm a pediatrician. And so, they often think, oh, you must work in healthcare or healthcare delivery. And we've actually chosen very intentionally to work in basic science research. In part because my training as a pediatrician at UCSF. As you both know, UCSF is a tertiary coronary care center where we see very unusual and rare cases of pediatric presentations. And it was there where I learned how little we knew about rare diseases and diseases in general and how powerful patients were. And that research was the pipeline for hope and for new discoveries for these families that often otherwise don't have very much access to treatments or cures. They have a PDF that maybe describes what their child has. And so, I decided to invest in basic science through CZI, but always saw the power of bringing rare disease patient cohorts. One, because if you've ever met a parent of a child with rare disease, they are a force to be reckoned with. Two, they can make research so much better due to their insights as patients and patient advocates. And I think they close the distance between basic science and impact in patients. And so, we've been working on that since 2019 and has been a passion of ours.Eric Topol (04:40):Wow, that's great. Now Jennifer, this IGI that you founded a decade ago, it's doing all kinds of things that are even well beyond rare diseases. We recently spoke, I know on Ground Truths about things as diverse as editing the gut microbiome in asthma and potentially someday Alzheimer's. But here you were very much involved at IGI with the baby KJ Muldoon. Maybe you could take us through this because this is such an extraordinary advance in the whole CRISPR Cures story.Jennifer Doudna (05:18):Yes, Eric. It's a very exciting story and we're very, very proud of the teamwork that went into making it possible to cure baby KJ of his very rare disease. And in brief, the story began back in August of last year when he was born with a metabolic disorder that prevented him from digesting protein, it's called a urea cycle disorder and rare, but extremely severe. And to the point where he was in the ICU and facing a very, very difficult prognosis. And so, fortunately his clinical team at Children's Hospital of Philadelphia (CHOP) reached out to Fyodor Urnov, who is the Director of Translational Medicine at the IGI here in the Bay Area. They teamed up and realized that they could quickly diagnose that child because we had an IRB approved here at the IGI that allowed us to collect patient samples and do diagnosis. So that was done.Jennifer Doudna (06:26):We created an off-the-shelf CRISPR therapy that would be targeted to the exact mutation that caused that young boy's disease. And then we worked with the FDA in Washington to make sure that we could very safely proceed with testing of that therapy initially in the lab and then ultimately in two different animal models. And then we opened a clinical trial that allowed that boy to be enrolled with, of course his parents' approval and for him to be dosed and the result was spectacular. And in fact, he was released from the hospital recently as a happy, healthy child, gaining lots of weight and looking very chunky. So it's really exciting.Eric Topol (07:16):It's so amazing. I don't think people necessarily grasp this. This timeline [see above] that we'll post with this is just mind boggling how you could, as you said Jennifer, in about six months to go from the birth and sequencing through cell specific cultures with the genome mutations through multiple experimental models with non-human primates even, looking at off-target effects, through the multiple FDA reviews and then dosing, cumulatively three dosing to save this baby's life. It really just amazing. Now that is a template. And before we go to this new Center, I just wanted to also mention not just the timeline of compression, which is unimaginable and the partnership that you've had at IGI with I guess Danaher to help manufacture, which is just another part of the story. But also the fact that you're not just even with CRISPR 1.0 as being used in approvals previously for sickle cell and β-thalassemia, but now we're talking about base editing in vivo in the body using mRNA delivery. So maybe you could comment on that, Jennifer.Jennifer Doudna (08:38):Yeah, very good point. So yeah, we used a version of CRISPR that was created by David Liu at the Broad Institute and published and available. And so, it was possible to create that, again, targeted to the exact mutation that caused baby KJ's disease. And fortunately, there was also an off-the-shelf way to deliver it because we had access to lipid nanoparticles that were developed for other purposes including vaccinations. And the type of disease that KJ suffered from is one that is treatable by editing cells in the liver, which is where the lipid nanoparticle naturally goes. So there were definitely some serendipity here, but it was amazing how all of these pieces were available. We just had to pull them together to create this therapy.Eric Topol (09:30):Yeah, no, it is amazing. So that I think is a great substrate for starting a new Center. And so, maybe back to you Priscilla, as to what your vision was when working with Jennifer and IGI to go through with this.Priscilla Chan (09:45):I think the thing that's incredibly exciting, you mentioned that at CZI our mission is to cure, prevent, and manage all disease. And when we talked about this 10 years ago, it felt like this far off idea, but every day it seems closer and closer. And I think the part that's super exciting about this is the direct connection between the basic science that's happening in CRISPR and the molecular and down to the nucleotide understanding of these mutations and the ability to correct them. And I think many of us, our imaginations have included this possibility, but it's very exciting that it has happened with baby KJ and CHOP. And we need to be able to do the work to understand how we can treat more patients this way, how to understand the obstacles, unblock them, streamline the process, bring down the cost, so that we better understand this pathway for treatment, as well as to increasingly democratize access to this type of platform. And so, our hope is to be able to do that. Take the work and inspiration that IGI and the team at CHOP have done and continue to push forward and to look at more cases, look at more organ systems. We're going to be looking in addition to the liver, at the bone marrow and the immune system.Priscilla Chan (11:17):And to be able to really work through more of the steps so that we can bring this to more families and patients.Eric Topol (11:30):Yeah, well it's pretty remarkable because here you have incurable ultra-rare diseases. If you can help these babies, just think of what this could do in a much broader context. I mean there a lot of common diseases have their roots with some of these very rare ones. So how do you see going forward, Jennifer, as to where you UC Berkeley, Gladstone, UCSF. I'm envious of you all up there in Northern California I have to say, will pull this off. How will you get the first similar case to KJ Muldoon going forward?Jennifer Doudna (12:13):Right. Well, IGI is a joint institute, as you probably know, Eric. So we were founded 10 years ago as a joint institute between UC Berkeley and UCSF. And now we have a third campus partner, UC Davis and we have the Gladstone Institute. So we've got an extraordinary group of clinicians and researchers that are coming together for this project and the Center to make it a success. We are building a clinical team at UCSF. We have several extraordinary leaders including Jennifer Puck and Chris Dvorak, and they are both going to be involved in identifying patients that could be enrolled in this program based on their diagnosis. And we will have a clinical advisory group that will help with that as well. So we'll be vetting patients probably right after we announce this, we're going to be looking to start enrolling people who might need this type of help.Eric Topol (13:18):Do you think it's possible to go any faster right now than the six months that it took for KJ?Jennifer Doudna (13:26):I think it could be. And here's the reason. There's a very interesting possibility that because of the type of technology that we're talking about with CRISPR, which fundamentally, and you and I have talked about this previously on your other podcast. But we've talked about the fact that it's a programmable technology and that means that we can change one aspect of it, one piece of it, which is a piece of a molecule called RNA that's able to direct CRISPR to the right sequence where we want to do editing and not change anything else about it. The protein, the CRISPR protein stays the same, the delivery vehicle stays the same, everything else stays the same. And so, we're working right now with FDA to get a platform designation for CRISPR that might allow streamlining of the testing process in some cases. So it'll obviously come down to the details of the disease, but we're hopeful that in the end it will be possible. And Priscilla and I have talked about this too, that as AI continues to advance and we get more and more information about rare diseases, we'll be able to predict accurately the effects of editing. And so, in some cases in the future it may be possible to streamline the testing process even further safely.Eric Topol (14:51):And I also would note, as you both know, well this administration is really keen on genome editing and they've had a joint announcement regarding their support. And in my discussions with the FDA commissioner, this is something they are very excited about. So the timing of the new Center for pediatric CRISPR Cures is aligned with the current administration, which is good to see. It's not always the case. Now going back, Priscilla, to your point that not just for the liver because delivery has been an issue of course, and we're going to try to get after a lot of these really rare diseases, it's going to go beyond there. So this is also an exciting new dimension of the Center, as you said, to go after the bone marrow for hematopoietic cells, perhaps other organs as well.Priscilla Chan (15:42):I mean what the expertise and feasibility, the immune system is going to be the next target. Jennifer Puck has been a pioneer in this work. She's the one who designed the newborn screen that will be the tool that picks up these patients as they are born. And I think the thing that's tremendous is the immune system, first of all is active in many, many diseases, not just these cases of children born with partial or absence of immune systems. And the course right now that these babies are left with is complete isolation and then a very long and arduous course of a bone marrow transplant with high morbidity and mortality. And even if after the transplant you have complications like graft versus host and immunosuppression. And so, the idea of being able to very specifically and with less the conditioning and morbidity and mortality of the treatment, being able to address this is incredible. And the implications for other diseases like blood cancers or other hematopoietic diseases, that's incredible. And that actually has an incredibly broad base of patients that can benefit from the learnings from these babies with severe combined immunodeficiencies.Eric Topol (17:10):Yeah, I think that goes back to a point earlier maybe to amplify in that previous CRISPR generation, it required outside the body work and it was extremely laborious and time consuming and obviously added much more to the expense because of hospitalization time. This is different. This is basically doing this inside the affected patient's body. And that is one of the biggest reasons why this is a big step forward and why we're so fortunate that your Center is moving forward. Maybe before we wrap up, you might want to comment, Jennifer on how you were able to bring in to build this platform, the manufacturing arm of it, because that seems to be yet another dimension that's helpful.Jennifer Doudna (18:01):Indeed, yes. And we were again fortunate with timing because you mentioned briefly that the IGI had set up a program with the Danaher Corporation back in January of last year. We call it our Beacon project. And it's focused on rare disease. And it's a really interesting kind of a unique partnership because Danaher is a manufacturing conglomerate. So they have companies that make molecules, they make proteins, they make RNA molecules, they make delivery molecules. And so, they were excited to be involved with us because they want to be a provider of these types of therapies in the future. And they can see the future of CRISPR is very exciting. It's expanding, growing area. And so, that agreement was in place already when the baby KJ case came to our attention. And so, what we're hoping to do with Danaher is again, work with them and their scientists to continue to ask, how can we reduce the cost of these therapies by reducing the cost of the molecules that are necessary, how to make them efficiently. We already, it's very interesting, Fyodor Urnov has toured their plant in North Dakota recently, and he found in talking to their engineers, there are a number of things that we can already see will be possible to do that are going to make the process of manufacturing these molecules faster and cheaper by a lot.Eric Topol (19:28):Wow.Jennifer Doudna (19:28):So it's a win-win for everybody. And so, we're really excited to do that in the context of this new Center.Eric Topol (19:36):Oh, that's phenomenal because some of these disorders you don't have that much time to work with before they could be brain or organ or vital tissue damage. So that's great to hear that. What you built here is the significance of it can't be under emphasized, I'll say because we have this May report of baby KJ, which could have been a one-off and it could have been years before we saw another cure of an ultra-rare disorder. And what you're doing here is insurance against that. You're going to have many more cracks at this. And I think this is the excitement about having a new dedicated Center. So just in closing, maybe some remarks from you Priscilla.Priscilla Chan (20:24):I just want to emphasize one point that's really exciting as we talk about these ultra-rare cases that they're often like one in a million. All these learnings actually help maximize the impact of lots of research across the sector that impacts actually everyone's health. And so, our learnings here from these patients that have very significant presentations that really can stand to benefit from any treatment is hopefully paving the way for many, many more of us to be able to live healthier, higher quality lives through basic science.Eric Topol (21:13):And over to you, Jennifer.Jennifer Doudna (21:15):Couldn't agree more. It's a really interesting moment. I think what we hope we are, is we're at sort of an inflection point where, as I mentioned earlier, all the pieces are in place to do this kind of therapeutic and we just need a team that will focus on doing it and pulling it together. And also learning from that process so that as Priscilla just said, we are ultimately able to use the same strategy for other diseases and potentially for diseases that affect lots of people. So it's exciting.Eric Topol (21:46):For sure. Now, if I could just sum up, this is now a decade past the origination of your work of CRISPR and how already at the first decade culminated in sickle cell disease treatment and β-thalassemia. Now we're into the second decade of CRISPR. And look what we've seen, something that was unimaginable until it actually happened and was reported just a little over a month ago. Now going back to Priscilla's point, we're talking about thousands of different rare Mendelian genomic disorders, thousands of them. And if you add them all up of rare diseases, we're talking about hundreds of millions of people affected around the world. So this is a foray into something much bigger, no less the fact that some of these rare mutations are shared by common diseases and approaches. So this really big stuff, congratulations to both of you and your organizations, the Innovative Genomics Institute and the Chan Zuckerberg Initiative for taking this on. We'll be following it with very deep interest, thank you.****************************************************Thanks for listening, reading and subscribing to Ground Truths.If you found this interesting PLEASE share it!That makes the work involved in putting these together especially worthwhile.Thanks to Scripps Research, and my producer, Jessica Nguyen, and Sinjun Balabanoff for video/audio support.All content on Ground Truths—its newsletters, analyses, and podcasts, are free, open-access.Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don't hesitate to post comments and give me feedback. Let me know topics that you would like to see covered.Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. Get full access to Ground Truths at erictopol.substack.com/subscribe

SynGAP10 weekly 10 minute updates on SYNGAP1 (video)
CENSUS, SYNGAP1. It is racing to a better future b/c of our families. #S10e174

SynGAP10 weekly 10 minute updates on SYNGAP1 (video)

Play Episode Listen Later Jul 7, 2025 15:51


July 7, 2025 Week 28   ADAMS CAMP https://curesyngap1.org/podcasts/syngap10/adams-camp-is-amazing-so-are-compression-vests-s10e110/    CENSUS & WHY WE WILL SEE MORE PATIENTS AAP recommends Whole Exome as a first line test for GDD/ID. https://www.linkedin.com/posts/ambry-genetics_exome-cns-patientforlife-activity-7343354049586466816-Jbq_   SYNGAP1 Census 2Q25 +55; new total 1,636, but we need to look at country by country to appreciate how low that is.  https://curesyngap1.org/census/ https://docs.google.com/spreadsheets/d/1oJwMysR2wyTxe91zLlKJglNa0NySPxkBF0PRiV6mBmM/edit?gid=0#gid=0 First patients from Bulgaria, Pakistan, Paraguay, and Uruguay.  US, Germany & France growing but UK standing still?   WARRIORS & PARENT STORIES https://curesyngap1.org/syngap-warriors/ Charlotte - Charlotte is 18 months old - diagnosed on May, 2025, just over a month ago. Already been to UNC and planning to go to CHOP.  17I thought it was worth noting the fast action this family is taking.   Martina - First patient from Uruguay.    SYNGAP1 Stories episode 35 Nicole Ciccone, son Jackson (from Georgia, near Atlanta) cureSYNGAP1.org/Stories   IMPORTANT SRF POSTS Webinar #108 - Repurposing opportunity for SYNGAP1 Specific nonsense mutations with Dr Bruce Bloom, Founder of Fortuity Pharma is up https://curesyngap1.org/resources/webinars/webinar-108-fortuity-pharma-repurposing-nonsense-mutations/   VOLUNTEER SHOUT OUT Suzanne Vreeland Jones for helping get the resource mobilization group organized in general and attending so many meetings, applying for grants, organizing the drive, and creating a fundraising plan for the rest of the year. And just generally caring about what's going on and what needs to get done. She's also the board chair and organizes all of that every 6 weeks. Then there's so much she's done and is doing for the conference so far as it is in Atlanta. We can trust it will be a nice event with her helping and being so close.   CONFERENCE - DECEMBER 4th & 5th Hotel has been selected for Atlanta - Georgia Tech Hotel & Conference Center; see cureSYNGAP1.org/Atlanta    FUNDRAISING - SIBLINGS ARE THE NEXT GEN OF SRF Fundraiser - LOVING ON LIAM - Emma's Hope for a SYNGAP1 Cure; fundraiser by Liam's sister Emma, who is promising a handmade pin for $5+ donations and over $100 a front flip off the diving board - cureSYNGAP1.org/Liam raised $2,370 in June!   WEBINAR #108 - Repurposing opportunity for SYNGAP1 nonsense mutations with Dr Bruce E. Bloom from Fortuity Pharma is up on YouTube https://youtu.be/4nqCLwuikIE?si=xWtbw-5OP_uMBwK5 and our website cureSYNGAP1.org/Webinars   PRESS RELEASE https://curesyngap1.org/blog/prof-kristian-stromgaard-awarded-cure-syngap1-grant-research-biomolecular-condensates-pr40/    WHY OUR RESEARCH MATTERS Bowie Lab Talk on Glutamatergic Neurons.  We learn about Intelligence from studying ID. https://www.youtube.com/watch?v=sfcN2BuZOJw   NUMBERS PUBMED 334, 26, so -1 vs. weeks. Follow on Youtube and LinkedIn, they matter. https://www.linkedin.com/company/curesyngap1/ 4,221 https://www.youtube.com/@CureSYNGAP1 1,390   #S10e173 CORRECTION I credited the Sprint blog to "probably Ed". Thanks, but that one was coordinated by Jo Ashline.   NICOLE'S POST I hate Autism Awareness Month. It stirs up so many emotions- anger, grief, and frustration for everything autism has taken from my son. Dear Syngap, It's me again. You'd think after all this time, we'd have some kind of understanding. But we don't. We never will. You barged into our lives uninvited, turned our world upside down, and refused to leave. You've taught me lessons I never asked for, dragged us down roads we never wanted to travel. You've humbled me, broken me, enraged me. I've cried because of you. Screamed into the silence. Begged the universe for answers it refuses to give. I've celebrated victories that should have been simple, ordinary things—but with you lurking in the shadows, nothing is ever simple. If I'm being honest, I hate you. I hate what you've done to my son. I hate that you've taken things from him that should have been his without question—his voice, his strength, his ease of movement, his peace. One day, he climbs like he was born to conquer mountains. The next, he struggles to take a step. You're a thief, Syngap. You steal his vision, rob him of his muscle tone, drain his energy until even smiling feels like work. You wrap yourself around his body, his mind, his very existence, and no matter how hard I fight, you never let go. You make him miserable. And I hate you for it. You turn his nights into a battlefield, his sleep stolen by seizures, restlessness, and the chaos you planted in his brain. You keep his words locked inside, hidden in a place I can't reach. And God, how I wish I could reach them. How I wish I could hear his thoughts, understand the words he wants so badly to say. Instead, I watch. I listen. I hold him when the frustration turns to tears, when his body betrays him, when he fights a battle most will never see. People don't see what I see. They don't hear the cries in the middle of the night or witness the exhaustion in his body. They don't see the war raging inside him. And me? I've been called crazy, overprotective, dramatic. But I don't care. I'll wear those labels like armor. Because as long as my son is fighting, I will fight harder. You tried to take so much from us. You tried to steal my marriage, tried to break my family apart, tried to strip away our joy. You've knocked us down, over and over again. But listen to me, Syngap: you will never have us. And here's the strangest thing. For all the hell you've put us through, you've also given me things I never expected. You've made me stronger than I ever thought possible. You've forced me to fight with a fierceness I didn't know I had. You've shown me how to love deeper, to celebrate what others overlook, to appreciate moments most take for granted. You take and you take—but somehow, you also build. You break, yet somehow, you make us unbreakable. But hear me loud and clear: you don't win. Tomorrow, my son will wake up, and despite you, he will rise. He will smile. He will fight. He will accomplish things you never thought he could. And I? I'll be there, standing beside him, fighting for him, daring you to try and stop us. You don't get the final say, Syngap. Not today. Not ever. My son is more than you. And you have underestimated his mother. Sincerely, A Syngap Momma

Legion of Comic Correction
EP 209 Best and Worst Comic Movies: MCU Phase 3

Legion of Comic Correction

Play Episode Listen Later Jul 4, 2025 23:02


Text us about COMICS! Or about whatever. It's your life. It's time to rank the MCU Phase 3!  Let's talk about Avengers Lite, planetary affairs, some REAL good Spider-Man, and the best team-up superhero movie TO DATE!  One, two, three, our opinions!New Episodes Every Week, mostly!Support us on Patreon! Get exclusive content! https://www.patreon.com/legionofcc SUBSCRIBE HERE: https://bit.ly/LegionOCCBrett Garwood - Man Behind The Curtain: https://redbagmedia.com/Our totally rad intro music comes from: Alex at Chop.it.up.productionsListen to our Podcast - Legion of Comic Correction - on all major podcasting platforms!Legion Website: legionofcc.comLCC Facebook: https://www.facebook.com/LegionofCC LCC Instagram: https://www.instagram.com/legionofcc/Support the show

Wrestling is Life is Wrestling with Cody Deaner

Tarik is a veteran independent professional wrestler from Ontario, Canada. He has wrestled all over the country and been in the ring with some of the best pro wrestlers of the modern era. He is known as "Mr. Punch, Kick, Chop." In this episode, Cody Deaner and Tarik explore the idea of how important it is to "Pay Your Dues." Not only in the world of professional wrestling... but also in life. Support Tarik by following him on Instagram: http://instagram.com/punchkickchop_tarik  Please support our sponsors at: Rest When Dead Clothing - http://restwhendead.ca CEO Fit Supplements - http://ceofit.ca Support this show: Join the Patreon: http://patreon.com/codydeaner To learn more about Cody's wrestling career and to book him, visit http://CodyDeaner.com To learn more about Cody's speaking career and to book him, visit http://ChrisGraySpeaks.com 

Daybreak Drive-IN
July 2, 2025: State schools to chop hundreds of degrees

Daybreak Drive-IN

Play Episode Listen Later Jul 2, 2025 2:16


ALSO: Big bill bounces back to the House... Fever take a titleSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

LA Poker Roundup
First Official Chop in WSOP History and Will New Tax Laws Kill Poker?!?! LA Poker Roundup Ep 88

LA Poker Roundup

Play Episode Listen Later Jul 2, 2025 85:57


Welcome to The LA Poker Roundup! The place for recent news and events in the LA poker community, with a focus on tournaments. This show will go over events happening the following week, the pros and cons of different events along with the opinions of your hosts. This week:01:53 Intro04:55 Blasters in WSOP Results30:49 Controversy surrounding WSOP Millionaire Maker40:46 What is Collusion50:37 Obligated to play a certain way on stream?1:00:53 Tax bill contains changes that could kill professional poker!1:12:38 Legends of Poker Schedule is out!1:22:28 Weekly RoundupRemember to subscribe and turn on notifications to catch each Roundup every week.Follow us on Twitter and Instagram LAPR Instagram: https://www.instagram.com/lapokerroundup/Ty's Twitter: https://twitter.com/TyDobbertinTy's Instagram: https://www.instagram.com/tydobbertin/Derek's Twitter: https://twitter.com/kwansfullDerek's YouTube: https://www.youtube.com/@10MinutePokerTipsDerek's Instagram: https://www.instagram.com/kwansfull/

TD Ameritrade Network
Ghabour: Chop Expected Into New All-Time Highs, Small Caps to Thrive

TD Ameritrade Network

Play Episode Listen Later Jun 30, 2025 7:35


"The higher we go, the more negative sentiment gets," says Eddie Ghabour. He considers the recovery off April lows the "most hated" bull rally he's seen. Eddie still expects that rally to continue in what he sees as a "non-recessionary environment" even if seasonal volatility emerges. Small caps are among the groups he expects to rally into the back half of the year.======== Schwab Network ========Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about

Redeemer PCA of Overland Park
Sermon: Vision of the Tree

Redeemer PCA of Overland Park

Play Episode Listen Later Jun 29, 2025 41:29


“The Vision of the Tree” Daniel 4:1-27             June 29, 2025 Pastor John Choi   ----more---- Daniel 4:20 The tree you saw, which grew and became strong, so that its top reached to heaven, and it was visible to the end of the whole earth, 21 whose leaves were beautiful and its fruit abundant, and in which was food for all, under which beasts of the field found shade, and in whose branches the birds of the heavens lived— 22 it is you, O king, who have grown and become strong. Your greatness has grown and reaches to heaven, and your dominion to the ends of the earth. 23 And because the king saw a watcher, a holy one, coming down from heaven and saying, ‘Chop down the tree and destroy it, but leave the stump of its roots in the earth, bound with a band of iron and bronze, in the tender grass of the field, and let him be wet with the dew of heaven, and let his portion be with the beasts of the field, till seven periods of time pass over him,' 24 this is the interpretation, O king: It is a decree of the Most High, which has come upon my lord the king, 25 that you shall be driven from among men, and your dwelling shall be with the beasts of the field. You shall be made to eat grass like an ox, and you shall be wet with the dew of heaven, and seven periods of time shall pass over you, till you know that the Most High rules the kingdom of men and gives it to whom he will. 26 And as it was commanded to leave the stump of the roots of the tree, your kingdom shall be confirmed for you from the time that you know that Heaven rules. 27 Therefore, O king, let my counsel be acceptable to you: break off your sins by practicing righteousness, and your iniquities by showing mercy to the oppressed, that there may perhaps be a lengthening of your prosperity.” True peace is found by humbly responding to God's revelation and receiving His mercy through Christ.       I.  The Illusion of Peace (1-4)        II.  The Interruption to Peace (5-26)       III.  The Invitation to True Peace (27)

Bar Crawl Radio
Stop the Chop: The beat goes on -- w/Melissa Elstein & Ken Coughlin

Bar Crawl Radio

Play Episode Listen Later Jun 27, 2025 41:21


“Stop the Chop” exists to eliminate non-essential helicopters from the skies above New York City – because – according to the "Stop the Chop" website: “Tourist, charter and commuter helicopter flights dramatically reduce the quality of life for millions of people in the metropolitan area. They pollute our environment, pose significant safety risks, harm our children, and make us miserable”It was a hot, second day of summer afternoon in Riverside Park – at the “You've Got Mail” promenade and garden. We sat on a bench and talked with our UWS neighbors about their concerns and questions regarding the Helicopter racket that invades our peaceful moments.Two experts, on the effects of the copter cacophony on our health and enjoyment of the our city parks, joined us -- Melissa Elstein and Ken Coughlin; both long-time NYC community organizers and environmental activists. Melissa was recently on BCR program #221 talking about “Love Your Street Tree Day” sponsored by the “West 80s Neighborhood Association” Hosted on Acast. See acast.com/privacy for more information.

Pascal Praud et vous
Jonathan Dassin : «C'est une fierté d'avoir chopé quelques-uns des traits de mon père Joe Dassin»

Pascal Praud et vous

Play Episode Listen Later Jun 26, 2025 15:16


Pascal Praud revient pendant deux heures, sans concession, sur tous les sujets qui font l'actualité. Aujourd'hui 26/06/2025, il recoit Joe Dassin pour évoquer le retour de la Croisière Claude François. Vous voulez réagir ? Appelez-le 01.80.20.39.21 (numéro non surtaxé) ou rendez-vous sur les réseaux sociaux d'Europe 1 pour livrer votre opinion et débattre sur les grandes thématiques développées dans l'émission du jour. Vous voulez réagir ? Appelez-le 01.80.20.39.21 (numéro non surtaxé) ou rendez-vous sur les réseaux sociaux d'Europe 1 pour livrer votre opinion et débattre sur grandes thématiques développées dans l'émission du jour.Distribué par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.

Third Down Gamble
Change the narrative.

Third Down Gamble

Play Episode Listen Later Jun 26, 2025 51:59


TSN's Luke Willson takes shots at the CFL product, was his take 'hot garbage'?  Chop blocks, why are they still in the game?  Quarterback injuries mount, again.  Roughrirders escape from Toronto with a 'Mario Miracle'... a moment for the ages.  Argonauts' Coach Ryan Dinwiddie fumes over third straight lost to start the 2025 CFL season.  (Mario Alford touchdown audio courtesy of 620 CKRM Cooperators Rider Broadcast Network; CFL on CBC theme music is used with express written permission; podcast recorded June 25, 2025).

CitizenCast
RFK Jr.'s conflicts of interest

CitizenCast

Play Episode Listen Later Jun 25, 2025 7:18


On this episode of Guest Commentary, we look at Trump's health secretary purging the CDC's vaccine advisory committee (including a renowned CHOP immunologist). He claimed they were in the pocket of the pharmaceutical industry. But who is really conflicted?

The Adam and Dr. Drew Show
Classic #1086 Hassan Chop!

The Adam and Dr. Drew Show

Play Episode Listen Later Jun 24, 2025 27:44


Adam shares his travel troubles to New York before he and Dr. Drew reflect on the lack of cultural awareness in their childhood, especially in media portrayals of the Middle East. They debate whether more government spending, like LA's proposed parcel tax, actually solves problems. The show ends with Adam's thoughts on Drew's new NYC apartment.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

PUMPDABEAT
Watch The Throne “ BLACKOUT “ Kiki Rumble Ball Aftermath w/Mook x Kae Diggy x Compadre DJ

PUMPDABEAT

Play Episode Listen Later Jun 23, 2025 69:05


Watch The Throne “ BLACKOUT “ Kiki Rumble Ball Aftermath ( DMV People's Choice Awards Ball Weekend 2025 ) BALTIMORE PRIDE DAY

Justice & Drew
Hour 3: I would Karate Chop that Child

Justice & Drew

Play Episode Listen Later Jun 20, 2025 39:16


Jon is joined in studio by MN Rep. Max Rymer, Grace Keating, and AK Kamara. Jon plays comments from Jasmine Crockett and the gang offers their opinions on a controversial news story. Taylor Swift prompts a political debate.

Midjourney : Fast Hours
Midjourney Video is HERE—Nerds React + New SREF System Chop-Up

Midjourney : Fast Hours

Play Episode Listen Later Jun 20, 2025 88:23


Rory's parents are laughing in the background. Drew just got a Midjourney tattoo that reads "/imagine". And somehow, Midjourney video dropped in the middle of all this.This week on Midjourney Fast Hours, the boys stumble into an accidental emergency episode because (surprise!), Midjourney just casually launched the most fun AI video tool yet. No press release. No tweetstorm. Just boom, it's here. And it works. Like, stupidly well.They run live experiments, break down what's working (and what's weird), and unpack the shockingly seamless auto-prompt, motion settings, extend feature, 4-up grid, and how it plays with SREF. Spoiler: SREF just got way more powerful—and more confusing. Also, Drew finds a way to sneak himself into a talking head video, naturally.Think you're burned out on AI? This might be the update that gets you feeling things again.---⏱️ Midjourney Fast Hour[00:00] Thursday night chaos & surprise video drop[03:40] Midjourney's whisper video launch strategy[05:10] A wave of feature updates: SREF, video, pricing[06:15] Long-term vision: real-time world-building[07:00] First impressions of Midjourney video[08:30] Auto-prompt is criminally good[09:55] High motion vs low motion—how to choose[12:24] The magical 4-grid video preview[14:00] Interface brilliance: simplicity done right[15:20] Observations on motion templates & quirks[17:00] Animation consistency & style fidelity[18:30] Old stills, new life—archive resurrection[20:00] Using SREFs to build entire worlds[22:50] Where the current video model falls short[24:20] Enter Topaz Astra—perfect timing for upscaling[26:00] A personal story on AI, portraits & impact[28:40] Upscaler comparisons: Magnific vs Bloom[30:00] Visual bugs: wheels, backwards cars & physics[32:00] Why hands magically fix themselves in video[34:00] Face consistency & surprising details[36:45] Sneaking Drew & Rory into an animated video[37:30] New Explore page for video (and why it rules)[38:50] The Extend feature is shockingly seamless[40:15] Camera direction tips for better results[42:20] Prompt control vs camera behavior when extending[44:10] Wild new video prompts spotted on Explore[47:00] Midjourney's edge: vibrant color retention[51:00] SREF update — what broke, what's better[54:15] Favorite tokens: dribbble.com, Nike ads, stoicism[57:40] Using songs, moods, and weirdcore to test SREF[59:15] How --exp interacts with --sref (and when to dial it down)[01:03:00] SV6 vs SV4 — why it matters now[01:08:00] Building smart prompt batches for testing[01:10:20] Describe tool to reverse-engineer SREF aesthetics[01:17:00] Style reference vs subject leakage test[01:23:45] Personalization wish list: can ranking images help?

Apostolic Revival Center
"Move stones, Chop wood and Carry water" | Rev. Justin Poindexter | 6.18.25

Apostolic Revival Center

Play Episode Listen Later Jun 19, 2025 80:09


"Move stones, Chop wood and Carry water" | Rev. Justin Poindexter | 6.18.25 by ARC of Carson City, NV

Firearms Radio Network (All Shows)
Let’s Go Hunt 128 – Smells like Gun in Here

Firearms Radio Network (All Shows)

Play Episode Listen Later Jun 17, 2025


Intro - Sam Welcome back to another episode of Let's Go Hunt! - Now with 100% less weeb: Vince H, restarting construction on that ark Mike Gonçalves, who is attending the conference of the “Part-Timers Podcast Guild” Dave Packard, whose pumped   And  Sam Alexander,    Around the Campfire: We are lost.   Not much at all. Don't burn yourself!   Eventual Ad Slot   Personal Gear Chat and Updates: Mike I went on a gobble hunt Dave Crawfish Etouffee https://www.youtube.com/watch?v=0cd-vcgWTYg Colorado Primary draw results Getting into elk shape Sam   Another long ass roadtrip and Yellerrock in the books. Turns out it was Memorial Day. Yeaaaaaaah.    Vince Done did my controlled hunt application It did awesome things with my minivan News and World Events Spotlighting With Dave:    What are some other uses for thermals? Subsonic 22LR: so  many ammo options, so what's the difference? What the Rut is going on here? or The Otter Creek Labs Polonium 30. What's it good for?   Reviews: Operation Shameless Bribery Gideon Optics affiliate coupon code: MOIST Camorado affiliate code: LETSGOHUNT   Outro - Vince Support the sport and take a buddy hunting! If you like that buddy, tell them about our show! If you don't, tell him his mom spearfishes for pigeon. Hit us up at lghpodcast.com.  Thanks for listening and Let's Go Hunt!    EMAIL: contact@lghpodcast.com Let's Go Hunt Archives - Firearms Radio Network Recipes: CRAWFISH ÉTOUFFÉE    2 Onions 2 Sticks of Celery 1 Green Bell Pepper 1 Red Bell Pepper 1 Bunch Green Onions 4 Cloves of Garlic 2 Sticks of Butter 1 Tablespoon Cajun or Creole Seasoning  1/4 Teaspoon Cayenne Pepper 1/4 Teaspoon of Salt 1/3 Cup of Flour 2 lbs Louisiana Crawfish 2 Cups of Hot Water (Add more if desired)   Start out by heating a Pot or Large Pan to a Medium/Low heat. Chop the Onion, Celery, Red Bell Pepper, Green Bell Pepper, and Green Onions.  Drop two Sticks of Butter into your hot pot and melt completely. Add the chopped vegetables to the pot and raise burner to a medium. Add the Cajun Seasoning, Cayenne Pepper, and Salt. Sauté for about 20 minutes.  Meanwhile chop the four cloves of Garlic.  After 20 minuets of sautéing, add the garlic and sauté for another 10 minutes.  After 10 more minuets of sautéing, push the vegetables to one side of the pot, add the 1/3 cup of flour and blend into the butter. Once the flour is mixed in well, stir everything altogether.  Sauté for another 30 minutes. Be very cautious during this time. If fire seems a little high, lower it.  Around this time you want to begin cooking some rice.  With about 3 minutes left of sautéing, begin heating 2 cups of water in the microwave.  Add a little bit of the hot water to the pot, and stir until it's a creamy mixture.  Add the Crawfish and rest of the hot water to the pot. Blend evenly.  Raise the heat to where you see a slight boil. Cover, and lower to a simmering heat. Cook for about 15-20 minutes.  If you feel as though you would like a thinner sauce, just add a little more water. However, taste to see if you need more seasoning. Enjoy Dat!

Going Dark - A Call of Duty Podcast
Don' Fall For the Black Ops 7 Hype...

Going Dark - A Call of Duty Podcast

Play Episode Listen Later Jun 17, 2025 80:37


WE ARE BACK! Chop and Tdawg discuss all the rumors of black ops 7 and go over where the heck we've been! #callofduty

Healing Horses with Elisha
73: Would your horse like a salad on the menu?

Healing Horses with Elisha

Play Episode Listen Later Jun 17, 2025 21:12


This week, our focus returns to the equine diet.Whether you are supporting overall health or addressing a particular issue in a horse, it always starts with their food. That often means identifying and removing dietary intolerances or introducing an anti-inflammatory or alkaline diet. Since each horse has a unique constitution, their diets must be individualized to support their specific sensitivities.Fresh Fruits and Vegetables for HorsesOffer a variety of fresh produce like melons, shredded beets, cucumbers, watermelon rind, apples, blueberries, and carrots. Chop them into small pieces for easy eating, and avoid feeding large amounts of stringy celery to horses with dental issues or a history of choking.Using Cauliflower and Other VeggiesMany horses enjoy nibbling on cauliflower occasionally. However, you should only feed it in small amounts since large quantities can cause gas. Always observe how your horse reacts to new foods and adjust accordingly.Incorporating HerbsAdd herbs (chamomile, mint, raspberry leaf, chickweed, plantain, and milk thistle) to salads or treats. Herbs provide added health benefits, especially raspberry leaf for mares and other reproductive support. Let your horse explore different herbs to see what they prefer.Preparing and Serving SaladsMake fresh horse salads once or twice a week, using any available clean or organic produce. If using non-organic items, wash them thoroughly. For picky eaters, introduce one ingredient at a time or mix new foods into their regular mash to help them adjust.Enrichment Through ForagingScatter chopped fruits, veggies, and herbs around the pasture to encourage natural foraging and gentle exercise. This “Easter egg hunt” approach is stimulating and rewarding for your horse.Enhancing FlavorSome horses enjoy a splash of apple cider vinegar or a little olive oil as a salad dressing. Experiment with small amounts to find what your horse likes best.Benefits of Fresh Salads for HorsesFeeding horses fresh salads regularly promotes better overall health, shinier coats, improved hoof condition, reduced inflammation, and more contentment. Fresh, live nutrients support the cells and tissues naturally.Moderation and Variety Are KeyAvoid feeding too much of any single ingredient. Provide a varied mix to allow your horse to enjoy different flavors and nutrients without overindulging in one thing, and always pay attention to its preferences and sensitivities.Tips for Horses with Specific ConditionsAvoid or chop stringy vegetables like celery finely for horses with dental problems or a history of choking. Salads and fresh foods can be particularly helpful for horses managing metabolic issues (EMS) by providing live nutrients without excess sugars or fats. Introducing fresh produce gradually and mixing it with regular feed helps sensitive horses adapt. Feeding a variety of herbs and fresh foods can support inflammation reduction, hoof health, and hormone balance, especially for mares. Always observe how your horse tolerates new foods and adjust accordingly.Links and resources:Connect with Elisha Edwards on her website Join my email list to be notified about new podcast releases and upcoming webinars.Free Webinar Masterclass: Four Steps to Solving Equine Metabolic Syndrome Naturally

The Philadelphia Sports Table | Philly Sports News & Views
The Flyers Upcoming Draft Is Huge! (PST Episode 620)

The Philadelphia Sports Table | Philly Sports News & Views

Play Episode Listen Later Jun 12, 2025 72:15


The Philadelphia Flyers upcoming draft is huge. Where this team goes in the future and where this rebuild lands is contingent on how well Flyers GM Danny Briere drafts at the end of June. Where might this team go with the No. 6 overall pick as well as the other two first-round picks the Flyers have? Charlie O'Connor from PHLY Sports joined us this week for a great pre-draft discussion!But first, the guys dove into some Philly sports history with some interesting stories about the Phillies and the Flyers. (Approx. 9:10)From there, the guys discussed the ups and downs of this Phillies season and how we should not be panicking at this point in the season. (Approx. 16:40)From there, they talked about something unprecedented. The guys gave their reactions to Eagles owner Jeffrey Lurie donating $50 million to the Children's Hospital of Pennsylvania to open the Lurie Autism Institute, the first of its kind in the nation. (Approx. 27:55)The NBA Draft board is changing, and that could mean the Sixers front office could be changing directions in terms of what they do at No. 3 overall. Could they pick V.J. Edgecombe? (Approx. 39:15)What they threw down on the Table this week was a fantastic and in-depth discussion with Charlie O'Connor from PHLY Sports about the future of the Flyers, their draft strategy, and what talent could come to this team after the NHL Draft. First, what has been the most consequential decision that Danny Briere has made thus far during his tenure as GM of this Flyers franchise? Talent to pick at No. 6 overall. What might the Flyers do with the No. 22 and No. 32 picks in the first-round? All of this and much more this week on the Table! (Approx. 49:55)SUBSCRIBE on YouTube: youtube.com/@thephiladelphiasportstableHead over to our website for all of our podcasts and more: philadelphiasportstable.comFollow us on BlueSky:Jeff: @jeffwarren.bsky.socialErik: @brickpollitt.bsky.socialFollow us on Threads:Jeff: @mrjeffwarrenErik: @slen1023The Show: @philadelphiasportstableFollow us on Twitter/X:Jeff: @Jeffrey_WarrenErik: @BrickPollittThe Show: @PhiladelphiaPSTFollow us on Instagram:Jeff: @mrjeffwarrenErik: @slen1023The Show: @philadelphiasportstable.Follow Jeff on TikTok: @mrjeffwarrenFollow us on Facebook: facebook.com/PhiladelphiaSportsTable

RARECast
A Gene Editing First Augurs an Era of Bespoke Therapies

RARECast

Play Episode Listen Later Jun 12, 2025 41:28


In a medical first, a team at Children's Hospital of Philadelphia and Penn Medicine has successfully treated an infant diagnosed with a rare genetic disorder by using a customized CRISPR gene editing therapy. The work, led by Penn Medicine's Kiran Musunuru and CHOP's Rebecca Ahrens-Nicklas, points to the potential to use bespoke gene editing therapies to treat others with rare genetic diseases for which no available medicines exist. We spoke to P.J. Brooks, deputy director of the Office of Rare Disease Research at the National Institutes of Health's National Center for Advancing Translational Sciences, about the breakthrough treatment, how the researchers were able to move from diagnosis to treatment with great speed, and what it would take to scale such an approach.

theWord
Chop it off?!

theWord

Play Episode Listen Later Jun 12, 2025 8:17


For 13 June 2025, Friday of the Tenth Week in Ordinary Time, based on Matthew 5:27-32

Talkin Shop with Coach Ballgame and Coach Chop
Episode 120: I'm NEW to Travel Ball

Talkin Shop with Coach Ballgame and Coach Chop

Play Episode Listen Later Jun 10, 2025 43:22


Ballgame and Chop go OG on Episode 120! Topics Discussed: Imposter Syndrome on a new team. Kids and Coaches getting discouraged during a losing streak. And what to do when the other team's coach drops lots of F bombs.Thanks for supporting the Pod!Bang!

Joe DeCamara & Jon Ritchie
Jeffrey Lurie donates $50 million to Autism Research at CHOP

Joe DeCamara & Jon Ritchie

Play Episode Listen Later Jun 10, 2025 21:32


The Morning Team reacts to news around the NFL.

Sports Gambling Podcast Network
LFA 210 Betting Guide (A Chop Up Thing) | MMA Gambling Podcast (Ep.842)

Sports Gambling Podcast Network

Play Episode Listen Later Jun 9, 2025 30:04


Jeff 'Chalkx' Fox and Daniel 'Gumby' Vreeland are back in your earholes with their LFA 210 betting guide! LFA hits up Freedom Hall in Louisville, Kentucky, this Friday for LFA 210, and the boys have your preview! Gumby is up 20 units on his regional MMA picks this year, and he looks to add to it with some live dogs on Friday night. Listen in and tag along!Time Stamps:0:00 - Intro6:08 - Ilyaz Mamadaliyev vs Lucas Faria10:02 - Mackenzie Stiller vs Sidney Trillo13:58 - Jackson McVey vs Mataeo Garner18:15 - Christian Natividad vs Jose Sandoval23:24 - Lance Lawrence vs Javier Reyes Exclusive SGPN Bonuses And Linkshttp://linktr.ee/sportsgamblingpodcastFollow The Sports Gambling Podcast X/Twitter - https://x.com/GamblingPodcastInstagram - https://www.instagram.com/sportsgamblingpodcastTikTok - https://www.tiktok.com/@gamblingpodcastFacebook - http://www.facebook.com/sportsgamblingpodcastFollow The Sports Gambling Podcast HostsSean Green - http://www.twitter.com/seantgreenRyan Kramer - http://www.twitter.com/kramercentricGambling problem? Call 1-800-GAMBLER CO, DC, IL, IN, LA, MD, MS, NJ, OH, PA, TN, VA, WV, WY Call 877-8-HOPENY or text HOPENY (467369) (NY) Call 1-800-327-5050 (MA)21+ to wager. Please Gamble Responsibly. Call 1-800-NEXT-STEP (AZ), 1-800-522-4700 (KS, NV), 1-800 BETS-OFF (IA), 1-800-270-7117 for confidential help (MI)

MMA Gambling Podcast
LFA 210 Betting Guide (A Chop Up Thing) (Ep.842)

MMA Gambling Podcast

Play Episode Listen Later Jun 8, 2025 30:04


Jeff 'Chalkx' Fox and Daniel 'Gumby' Vreeland are back in your earholes with their LFA 210 betting guide! LFA hits up Freedom Hall in Louisville, Kentucky, this Friday for LFA 210, and the boys have your preview! Gumby is up 20 units on his regional MMA picks this year, and he looks to add to it with some live dogs on Friday night. Listen in and tag along! Time Stamps:0:00 - Intro6:08 - Ilyaz Mamadaliyev vs Lucas Faria10:02 - Mackenzie Stiller vs Sidney Trillo13:58 - Jackson McVey vs Mataeo Garner18:15 - Christian Natividad vs Jose Sandoval23:24 - Lance Lawrence vs Javier Reyes Exclusive SGPN Bonuses And Linkshttp://linktr.ee/sportsgamblingpodcastFollow The Sports Gambling Podcast X/Twitter - https://x.com/GamblingPodcastInstagram - https://www.instagram.com/sportsgamblingpodcastTikTok - https://www.tiktok.com/@gamblingpodcastFacebook - http://www.facebook.com/sportsgamblingpodcastFOLLOW The Hosts On Social MediaJeff Fox - http://www.twitter.com/jefffoxwriterDaniel Vreeland - http://www.twitter.com/gumbyvreelandShow - http://www.twitter.com/sgpnmmaGambling problem? Call 1-800-GAMBLER CO, DC, IL, IN, LA, MD, MS, NJ, OH, PA, TN, VA, WV, WY Call 877-8-HOPENY or text HOPENY (467369) (NY) Call 1-800-327-5050 (MA)21+ to wager. Please Gamble Responsibly. Call 1-800-NEXT-STEP (AZ), 1-800-522-4700 (KS, NV), 1-800 BETS-OFF (IA), 1-800-270-7117 for confidential help (MI)

Becker’s Healthcare Podcast
Driving Innovation and Expanding Access in Pediatric Healthcare: A Conversation with Sophia Holder of CHOP

Becker’s Healthcare Podcast

Play Episode Listen Later Jun 7, 2025 15:00


In this episode, Sophia Holder, Executive Vice President and CFO of Children's Hospital of Philadelphia, shares how CHOP is investing in AI, automation, and strategic partnerships to transform pediatric care, improve access, and build a more sustainable healthcare future.

Okayest Cook
Collin Hilton - The World Food Champion

Okayest Cook

Play Episode Listen Later Jun 7, 2025 66:33


Exploring the Culinary World with Chef Collin Hilton In this episode of the Okays Cook podcast, host Chris Whonsetler engages in an enlightening conversation with renowned chef Collin Hilton at CRG Grow. Collin shares his culinary journey, discusses his experience winning the World Food Championship, and provides insights into making his pasta in broth gourmet dishes. The episode dives deep into his innovative cooking techniques and the philosophy behind using real ingredients. Additionally, Collin offers practical tips for making homemade pasta, tackles common challenges, and reveals some of his favorite creative twists on traditional recipes. The discussion also covers Colin's upcoming ventures and contributions to the culinary scene, making it a must-listen for food enthusiasts and aspiring chefs alike. 00:00 Road Trip Begins 00:29 Welcome to the Okayest Cook Podcast 00:35 Discussing the CRG Grow Garden 00:56 Backcountry Hunters and Anglers Rendezvous 01:12 The Double Meaning of the new Okayest Cook Stickers 01:54 Eat Real Food Philosophy 02:39 Cooking and Events at CRG Grow 03:42 Challenges of Home Gardening 04:12 Cilantro and Coriander: A Flavorful Discussion 05:35 World Food Champion and Traeger Game Day Ring 06:59 Notable Meals and Tofu Talk 09:28 Exploring Sichuan Pepper and Habanero 14:04 Chef Colin Hilton's Culinary Journey 21:38 World Food Championship Dish Breakdown 33:19 MOKAO Event and Dish Insights 34:17 The Coffee Element in Pasta 34:49 Incorporating Chocolate in Savory Dishes 35:15 Unique Flavor Combinations 36:17 Presentation and Practicality 37:51 Challenges of Cooking with Coffee and Chocolate 39:29 Building a Balanced Dinner 50:59 Exploring Pasta Shapes and Techniques 52:48 Tips for Making Perfect Pasta 53:46 The Importance of Resting Dough 59:01 Cunningham Restaurant Group and Future Plans Collins Pasta Recipe: Green Seaweed Dough 6 g Aonori (nori powder) 42 g Basil 170 g Whole Egg 50 g Egg yolk 6 g Salt 10 g EVOO 360 g OO flour Water As needed Earthy Orange Dough 300 g 00 flour 60 g Buckwheat 10 g EVOO 5 g Salt 150 g Whole Egg 50 g Egg Yolk 40 g Tomato Paste   Regular Pasta Dough 360 g 00 flour (3 cup) 10 g EVOO 5 g Salt 150 g Whole Egg (about 3) 60 g Egg Yolk (about 3) Water as needed Scale flour into bowl.  Form a crater in the middle and scale salt, EVOO, Whole eggs and Egg yolks into the center (if adding other liquid, now is the time to mix in. If it's an herb, chop it or blend it up first, then mix it in as liquid).  Mix with spatula until loose clumps are formed.  Transfer to a clean work surface, scraping all remaining dough off the spatula and out of the bowl.  Chop and mix with bowl scraper.  Begin kneading until smooth ball consistency, adding a few drops of water as needed.  About 8 minutes.  Wrap in plastic and rest 30 minutes before rolling into desired shape. Find Collin & CRG: Collin Hilton: https://www.instagram.com/collinhiltoncooks/ Cunningham Restaurant Group: https://www.crgdining.com/restaurants/ Insta: https://www.instagram.com/crgrestaurants/ CRG Grow: https://www.instagram.com/crggrow/ Mentioned in Episode: Row 7 seeds - https://www.row7seeds.com/ habanada - https://www.row7seeds.com/products/habanada-pepper-seeds?_pos=1&_psq=haba&_ss=e&_v=1.0 Dr. Hoby - https://www.instagram.com/hobywedler/ Nate Spangle - https://open.spotify.com/episode/4ejTpcErpgjo4Evu8zUi7O?si=ec5b6d7b925f4571 World Food Championship - https://worldfoodchampionships.com/ Insta: https://www.instagram.com/worldfoodchampionships/ Food Science Books to look for: On Food and Cooking by Harold McGee: http://bit.ly/4mN0VlU The Food Lab by Kenji López-Alt: https://amzn.to/4dNw5pg More at OkayestCook.com Connect with us on Instagram @Okayest_Cook And facebook.com/AnOkayestCook Video feed on YouTube.com/@OkayestCook Crew:  Chris Whonsetler Email: Chris@OkayestCook.com Web: ChrisWhonsetler.com Instagram: @FromFieldToTable & @WhonPhoto

40 Days for Life Podcast
Hope, STDs, and "the Chop"--PODCAST Season 10, Episode 22

40 Days for Life Podcast

Play Episode Listen Later Jun 3, 2025 43:38


Planned Parenthood released its 2023-24 annual report. And it's so insane it merits its own podcast episode. AGAIN. On this episode of The 40 Days for Life Podcast, former Planned Parenthood manager Ramona Trevino joins us to break down the most unhinged excerpts of Planned Parenthood's annual report. We discuss: What is virginity (according to Planned Parenthood)? The stunning number of donors Planned Parenthood lost in the last year; How Planned Parenthood finds hope in...sexually transmitted infection testing?

AllDolphins Podcast
Episode 512: Wilson, Chop, Jonnu, and Open OTA Highlights

AllDolphins Podcast

Play Episode Listen Later Jun 3, 2025 42:09


Miami Dolphins on SI Publisher Alain Poupart (@PoupartNFL) is joined by Chris Perkins from the South Florida Sun-Sentinel to discuss everything that went down before, during and after the second Dolphins OTA open to the media, including updates on Ramsey, Jonnu Smith, Zach Wilson, Tua, Chop, and more. Make sure to follow Alain on Twitter at @PoupartNFL and Blusky at @alainpoupart.bsky.social, and read his stories (free content) on Miami Dolphins on SI at si.com/nfl/dolphins.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Buck's Beat
The Buck Belue Show 6-2-25 Hour 2

Buck's Beat

Play Episode Listen Later Jun 3, 2025 37:04


Hear "The Buck Belue Show" every weeknight from 6-8pm on 680 The Fan ad 93.7 FM, the 680 The Fan App available on Apple and Android, with your Smart Speaker by saying Alexa or wherever you get and listen to your favorite podcast! Get the latest on Georgia sports, newsmakers, and more! GT's Athletic Director leaving CF Nugget - Heisman favorites Chop it Up - Who are the All-Stars Top 5 See omnystudio.com/listener for privacy information.

Just Grow Something | A Gardening Podcast
The Chelsea Chop: How to Prune for Longer Blooms and Healthier Plants - Ep. 252

Just Grow Something | A Gardening Podcast

Play Episode Listen Later Jun 3, 2025 18:08


In this short and snippy episode, we dig into a classic gardening technique known as the Chelsea Chop. Named after the iconic RHS Chelsea Flower Show, this late spring/early summer pruning method can help home gardeners promote bushier growth, delay blooms for season-long color, and support pollinators with flowering perennials in the garden.If you're looking to add more beauty to your veggie garden and boost the productivity of your perennials, this episode is your green-thumb guide to giving those flowers a haircut.Today on Just Grow Something we're talking:What the Chelsea Chop is and why it's doneIdeal plants for the technique (Echinacea, Rudbeckia, Sedum, Phlox, and more)Different pruning strategies and how to choose the right oneThe timing of the chop based on your climate and plant maturityBenefits for both aesthetics and garden health (more airflow, fewer pests!)The Chelsea Chop is more than just a cut—it's a strategic move to shape your garden and support pollinators. Let's dig in!References and Resources:Save 20% on your new own-root rose plant atHeirloomRoses.com with code JUSTGROW https://heirloomroses.comRHS Chelsea Chop: https://www.rhs.org.uk/pruning/chelsea-chopBBC Gardener's World, How to Do the Chelsea Chop: https://www.gardenersworld.com/plants/how-to-do-the-chelsea-chop/Just Grow Something: https://justgrowsomething.comJust Grow Something Merch andDownloads: https://justgrowsomething.com/shopJust Grow Something Gardening Friends Facebook Group:https://www.facebook.com/share/g/18YgHveF5P/Check out how you can become a patron on Patreon: https://www.patreon.com/JustGrowSomethingBonus content for supporters of the Podcast: https://buymeacoffee.com/justgrowsomethingAmazon storefront: https://www.amazon.com/shop/justgrowsomething

The Dom Giordano Program
Selling Sanctuary

The Dom Giordano Program

Play Episode Listen Later May 30, 2025 43:23


1 - PA Representative Scott Perry joins us. How big and beautiful is that Trump bill? What can be done on tax on tips and lowering taxes in general? How much can be slashed while keeping our principles? Why are Republicans holding out? What will be done to Medicaid? How will school choice play out in the Commonwealth and beyond? What's the problem with the Nippon Steel deal? Is Scott satisfied with the FBI's latest messaging? 120 - Your calls. 135 - Beth Ann Rosica joins us to tell us just what a “Sanctuary City” really is. How much has that definition changed over the last year when she wrote her article on the matter? Which County sticks out as a “Sanctuary county”. Where does Bucks County stand? Why does Beth Ann think these sanctuary policies are so ridiculous? The conversation moves to CHOP and their decision to remove gender transition surgery, but keep hormone therapy as an option. 150 - Your calls to round out the hour.

The Dom Giordano Program
For Better or Worse, Mostly Worse (Full Show)

The Dom Giordano Program

Play Episode Listen Later May 30, 2025 132:12


12 - Dom kicks off Friday with a few stories, including the transgender runner out in California, Vance vision for what Trump is doing, and local governments slacking in their duties. 1215 - Side - inventions that made the world worse. You want AI driving that car? 1220 - How many Tesla owners have experienced people inflicting intentional damage to their cars because of Elon? How much has their insurance gone up because of it? Are people getting duped online by AI cake designs? How will Elon be honored today? 1235 - Senior Director of Labor Policy with the Commonwealth Foundation David R. Osborne joins us to uncover the mystery of “Rubber Rooms” here at our Philadelphia Public Schools. What are Rubber Rooms? Why did Commonwealth start looking into this situation? Why do these rubber rooms exist? What are they asking for in their information request? What will they do with the info? What can Harrisburg do to remedy this issue? 1245 - Does Dom know what he's talking about with AI? 1250 - Adam Carolla has some colorful thoughts on no tax on tips. 1 - PA Representative Scott Perry joins us. How big and beautiful is that Trump bill? What can be done on tax on tips and lowering taxes in general? How much can be slashed while keeping our principles? Why are Republicans holding out? What will be done to Medicaid? How will school choice play out in the Commonwealth and beyond? What's the problem with the Nippon Steel deal? Is Scott satisfied with the FBI's latest messaging? 120 - Your calls. 135 - Beth and Rosica joins us to tell us just what a “Sanctuary City” really is. How much has that definition changed over the last year when she wrote her article on the matter? Which County sticks out as a “Sanctuary county”. Where does Bucks County stand? Why does Beth Ann think these sanctuary policies are so ridiculous? The conversation moves to CHOP and their decision to remove gender transition surgery, but keep hormone therapy as an option. 150 - Your calls to round out the hour. 2 - Protect Our Coast NJ's Robin Shaffer joins us today to discuss how New Jersey is fighting back against New York's coastline plans that will end up affecting the Garden State. What is New York hoping to accomplish with a possible new pipeline? Are Americans going to be working on this project? 205 - We go live to Trump's press conference with Elon from the Oval Office. 215 - Dom's Money Melody! 220 - We go to questions from reporters to Elon and Trump and it kicks off with some fireworks! 225 - Your calls. 235 - San Francisco of all places is pushing back on student equity! Why? Because the schooling has gone too far. 240 - Your calls. 250 - The Lightning Round!

AllDolphins Podcast
Episode 510: Open OTA Wrap-Up, Who Stood Out, and More

AllDolphins Podcast

Play Episode Listen Later May 28, 2025 36:48


Miami Dolphins on SI Publisher Alain Poupart (@PoupartNFL) is joined by Chris Perkins from the South Florida Sun-Sentinel to discuss everything that went down before, during and after the Dolphins OTA open to the media, including updates on Ramsey, Tyreek, Chubb, Chop, and more. Make sure to follow Alain on Twitter at @PoupartNFL and Blusky at @alainpoupart.bsky.social, and read his stories (free content) on Miami Dolphins on SI at si.com/nfl/dolphins.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

GrowCast: The Official Cannabis Podcast

Make sure to check out the OKCalyxx Natural Farming Immersive on Oct 11 & 12th - grab your tickets at www.growcast.com/events  DON'T throw away your fan leaves. The reason they are healthy green is because they contain all those precious nutrients you paid for! OKCalyxx is back on the show to talk about closing the loop in both your indoor and outdoor gardens. He gives an update on the developments at his property where he is regenerative farming. From pursuing beavers for their chips, to raising chickens for eggs, shells, and manure- OKCalyxx has bootstrapped his own closed loop system.... For minimum investment. Calyxx also elaborates one some of his plans for breeding, including his work with Cherryanna Grande and his new Orangalina cut.  (00:00) Introduction (04:39) Beaver Sighting and Chips (07:49) Morel Mushrooms and Fungal Soil Health (14:17) Plant Stress and Resilience (28:30) Raising Chickens for the Grow (44:09) Utilizing Fan Leaves and Nutrient Reclamation (50:52) Chop and Drop and Indoor Growing (1:00:07) Using Fan Leaves for Rehydration (1:12:18) Final Thoughts and Shoutouts   Join GrowCast Membership TODAY! Connect with the most active, vibrant cannabis community in the entire world. Personal 24/7 garden support, Members Only content and discounts, and so much more! www.growcast.com/membership    GrowCast Seed Co KLM DROP IS LIVE! Members get $20 off per pack- this Key Lime Madness Drop is going fast so don't miss it! Code growcast15 now works with grow KITS from AC Infinity! www.acinfinity.com use promo code growcast15 for 15% off the BEST grow fans in the game, plus tents, pots, scissors, LED lights, and now REFILLABLE FILTERS!

Fit, Healthy & Happy Podcast
704: 11 Healthiest Meals & Snacks To Eat In A Pinch

Fit, Healthy & Happy Podcast

Play Episode Listen Later May 22, 2025 16:55


➢ DM “RECIPE GUIDE” to IG @ ColossusFit and we'll send you 53 high protein, easy to make recipes.Summary of episode:In this episode we go over 11 healthy meal and snack options to eat in a pinch.Meals:1- (01:05) Rotisserie Chicken + Salad + Minute Rice2- (02:44) Protein SmoothieWhey protein + banana + frozen berries + spinach + milk(5 different protein recipes at the end of our guide for free) Cinnamon roll, green glow.3- (05:16) Tuna salad lettuce wrapsPut the tuna and half of the oil from the can in a bowl and mix with the tomato puree.Chop the red onion as fine as possible and add to the tuna. Cut the apple in 2 parts and remove the core. Chop the apple into small cubes and also add to the tuna. Mix everything.Spread the tuna over the 8 lettuce leaves and serve as wraps.4- (06:45) Greek Yogurt BowlPlain greek yogurt, berries, seeds, honey5- (07:32) Overnight Oats+ Protein Scoop + Berries- Add cinnamon or flaxseeds for extra nutrition.Snacks:6- (09:01) Hummus + Baby Carrots or Bell Pepper Strips-Whole grain pita chips are a great add-on.7- (10:16) Apple or banana with peanut butter8- (11:19) Protein Bar or Beef Jerky + Piece of Fruit9- (12:49) Canned Tuna or Salmon + Whole Grain Crackers + Cherry TomatoesAdd mustard, Greek yogurt, or hot sauce for flavor.Slightly longer to make meals, but still efficient and solid10- (14:03) Turkey burgers11- (15:17) Chicken wrapsThanks for listening! We genuinely appreciate every single one of you listening.➢Follow us on instagram @colossusfit➢Apply to get your Polished Physique: https://colossusfitness.com/

Bertcast
Something's Burning: If We Had $60,000,000, We'd ALL Be Rich | Ed Robertson + Mark McGrath | S5 E13

Bertcast

Play Episode Listen Later May 20, 2025 113:54


Sugar Ray and Barenaked Ladies lead singers, Mark McGrath and Ed Robertson, swing by my kitchen to discuss the music industry, how their songs affected my life, and getting older. I make ‘em Chinese Chicken (of course) and we ALL sing One Week. Because, you have to. Catch them on tour TOGETHER this summer… Last Summer on Earth Tour - https://www.barenakedladies.com/tour-2 Follow Mark McGrath: https://www.instagram.com/therealmarkmcgrath Follow Ed Robertson: https://www.instagram.com/barenakedladiesmusic SUBSCRIBE so you never miss a video https://bit.ly/3DC1ICg Stream LUCKY on Netflix https://www.netflix.com/title/81713944 PERMISSION TO PARTY WORLD TOUR is on sale now: http://www.bertbertbert.com/tour For all things BERTY BOY PRODUCTIONS: https://bertyboyproductions.com For MERCH: https://store.bertbertbert.com/ Follow Me! Facebook: http://www.Facebook.com/BertKreischer Instagram: http://www.Instagram.com/bertkreischer YouTube: http://www.YouTube.com/user/Akreischer TikTok: http://www.TikTok.com/@bertkreischer Threads: https://www.threads.net/@bertkreischer X: http://www.Twitter.com/bertkreischer Text Me: https://my.community.com/bertkreischerDRUNKEN NOODLES W/ CHINESE CHICKENDrunken Noodles:Sauce:* 3 TBS oyster sauce* 2 TBS light soy sauce* 2 TBS dark soy sauce* 1 TBS rice wine vinegar* ½ TBS fish sauce* 1 TBS brown sugar* 2 TBS waterStir-Fry:* 7 ounces dried wide rice noodles* 1 TBS sesame oil* 1 brown onion* 1 TBS grated garlic* 1 carrot, julienned* 1 bunch Bok choy, chopped* 4 scallion stems, sliced* 1 firmly packed cup basil leaves* Chili oil * Crushed roasted peanuts1. Mix together ingredients for sauce.2. Cook rice noodles, then rinse with cold water before draining.3. Heat sesame oil in pan. Add onion and garlic. Add carrot, Bok choy, spring onion, noodles, and stir-fry sauce. Toss well until combined. Remove and serve with basil leaves, topping with chili oil and crushed peanuts.Yu Xiang ChickenChicken Marinade: * ½ tsp kosher salt* 3 tsp potato starch* 4 tsp Rice Wine* 2 TBS light soy sauce* 1 tsp sesame oilSauce: * 2 tsp potato starch* 2 TBS white sugar* Salt* ¼ tsp light soy sauce* 4 TBS Rice Wine* 2 TBS Chinkiang vinegar* 1 tsp dark soy sauce* 2 tsp sesame oil* 2 tsp pure chili oil* ½ cup & 4 TBS waterStir-Fry:* ¼ cup cloud ear mushrooms* ½ cup peanut oil* 4-6 TBS chopped pickled red chilis* 2 spring onions, chopped, white and green parts separated* 4 TBS minced ginger* 12 garlic cloves, minced* 1-10 fresh red chilis * 6-20 dried red chilis, snipped into ½” pieces* ½ cup sliced bamboo shoots1. Slice chicken into thin strips. Combine chicken with salt, potato starch, rice wine, light soy sauce, sesame oil, mixing well, then let marinate.2. Combine all sauce ingredients to make sauce3. Chop spring onion, ginger, garlic, fresh red chilies, and snip the dried red chilis into ½” pieces. Drain and rinse bamboo shoots.4. Bring pot of water to a boil and add sliced mushrooms and bamboo shoots boiling for 1-2 minutes then drain in fine mesh strainer and rinse with cold water.5. Heat peanut oil over high heat then add marinated chicken, stir-frying for 40 seconds. Transfer to strainer and let excess oil drip back into wok. Remove all but 3 TBS of oil from wok.6. Heat oil in wok and add pickled red chilis. Then add spring onion white and light green parts, ginger and garlic. Add fresh and dried chilies cooking for 1 minute, then add sliced mushrooms and bamboo shoots.7. Add chicken and sauce into wok. Serve and garnish with dark green parts of spring onion. Learn more about your ad choices. Visit megaphone.fm/adchoices