Podcasts about Alternative model

Have you ever felt like losing one person would destroy your entire life… even while the relationship itself was destroying you?In this episode of The BPD Bunch, Xannie, Carys, André, Mo, and Justin talk openly about the intense, chaotic, and often painful relationship patterns that can happen with Borderline Personality Disorder. From abandonment panic and toxic relationship cycles to oversharing, emotional testing, and confusing drama for intimacy, the cast explores what closeness looked like when their BPD symptoms were at their worst.This season, we're discussing BPD through the lens of the Alternative Model of Personality Disorders (AMPD). Under the AMPD, difficulties with intimacy are considered part of impairments in interpersonal functioning, alongside empathy. To meet criteria for BPD in this model, a person must have difficulties in at least two areas of personality functioning: identity, self direction, empathy, or intimacy, along with four or more pathological personality traits, which we'll be discussing in more detail later this season.In this episode:* BPD and intimacy* Fear of abandonment* Toxic relationship dynamics* Push-pull relationships* Emotional dependency* Oversharing and testing people* BPD and friendships* Relationship obsession* Emotional reactivity in relationshipsIf you've ever confused emotional chaos with love, stayed in relationships that were hurting you, or felt terrified of someone pulling away, this episode is for you.In the first two episodes of the season, Dr. Carla Sharp, Dr. Frank Yeomans, and Dr. Alex Stein explain what the AMPD is, how it changes from the current categorical model, and how the BPD diagnosis is changing. In case you missed it, here are the links:Watch part 1 hereWatch part 2 here⸻

Can someone with BPD feel other people's emotions so intensely that it actually starts getting in the way of empathy?In this episode of The BPD Bunch, Xannie, Georgette, André, Solène, and Katja continue their conversation about BPD and empathy by exploring the difference between emotionally feeling with someone and actually understanding what they need. They share their top tips, lessons and skills they use to navigate empathy more effectively.In case you're new here, this season, we're discussing BPD through the lens of the Alternative Model of Personality Disorders (AMPD). Under the AMPD, difficulties with empathy are considered part of impairments in interpersonal functioning, alongside intimacy. To meet criteria for BPD in this model, a person must have difficulties in at least two areas of personality functioning: identity, self direction, empathy, or intimacy, along with four or more pathological personality traits, which we'll be discussing in more detail later this season.In this episode:* BPD and empathy* Cognitive vs affective empathy* Emotional mirroring* Rejection sensitivity* Social paranoia* Problem solving vs listening* Emotion regulation and empathy* “Feeling everything” with BPD* The empathy trap* Learning to ask what people needIf you've ever absorbed other people's emotions, assumed you knew what someone needed, taken neutrality personally, or felt emotionally overwhelmed in relationships, this episode is for you.In the first two episodes of the season, Dr. Carla Sharp, Dr. Frank Yeomans, and Dr. Alex Stein explain what the AMPD is, how it changes from the current categorical model, and how the BPD diagnosis is changing. In case you missed it, here are the links:Watch part 1 hereWatch part 2 here⸻

Can someone with BPD care about other people and still behave in profoundly unempathetic ways?In this episode of The BPD Bunch, Xannie, Georgette, André, Solène, and Katja explore the uncomfortable reality that Borderline Personality Disorder can sometimes make people so emotionally reactive, hypervigilant, and consumed by fear that they stop accurately understanding or trusting other people's emotions, intentions, and experiences.This season, we're discussing BPD through the lens of the Alternative Model of Personality Disorders (AMPD). Under the AMPD, difficulties with empathy are considered part of impairments in interpersonal functioning, alongside intimacy. To meet criteria for BPD in this model, a person must have difficulties in at least two areas of personality functioning: identity, self direction, empathy, or intimacy, along with four or more pathological personality traits, which we'll be discussing in more detail later this season.In this episode:* BPD and empathy* Social paranoia in BPD* Misreading neutrality as rejection* Reassurance seeking* Fear of abandonment* Mind-reading and projection* Why emotional overwhelm can reduce empathyIf you've ever convinced yourself someone secretly hated you, struggled to trust reassurance, replayed social interactions for hours, or felt overwhelmed by other people's emotions, this episode is for you.In the first two episodes of the season, Dr. Carla Sharp, Dr. Frank Yeomans, and Dr. Alex Stein explained what the AMPD is, how it changes from the current categorical model, and how the BPD diagnosis is changing. If you missed them check them out:Part 1Part 2⸻

Do you struggle to know what you want, stick with a path, or trust your own choices?In this episode of The BPD Bunch, Xannie, Madhurima, Carys and Solène continue their discussion of BPD and self-direction through the lens of the Alternative Model for Personality Disorders (AMPD), exploring how goals, values, identity, relationships, and recovery can all affect the way we build a life.This episode is for anyone with BPD who has ever wondered why it can feel so hard to know who you are, what you want, or where you're going.We talk about:* BPD and self-direction* changing goals, values, and interests* favorite people and life decisions* identity, emptiness, and sense of self* perfectionism, recovery, and self-acceptance* learning how to follow through without getting trapped* finding direction while still allowing yourself to changeThis is part of our Season 7 series where we're breaking BPD down in a more real, human way while also connecting it to newer ways of understanding personality.Follow Xannie and Solene's music journey  ⁨@Nxi-Sol⁩  In the first two episodes of the season, Dr. Carla Sharp, Dr. Frank Yeomans, and Dr. Alex Stein explained what the AMPD is, how it changes from the current categorical model, and how the BPD diagnosis is changing. ⸻

What happens when BPD affects your goals, career choices, and sense of direction in life?In this episode of The BPD Bunch, Xannie, Madhurima, Carys, and Solène talk about self-direction through the lens of the Alternative Model for Personality Disorders.We explore:• why people with BPD may struggle to stick with one job or career• constantly changing direction and starting over• tying your identity to work and what happens when that falls apart• being influenced by other people's goals or expectations• the belief that if it's “right,” it should feel easy• how self-direction connects to identity and recoveryIf you've ever asked yourself “what am I doing with my life?” and felt like the answer keeps changing, this episode is for you.This is part of our Season 7 series where we're breaking BPD down through the lens of the Alternative Model of Personality Disorders.In the first two episodes of the season, Dr. Carla Sharp, Dr. Frank Yeomans, and Dr. Alex Stein explained what the AMPD is, how it changes from the current categorical model, and how the BPD diagnosis is changing. In case you missed it, here are the links:Watch part 1 here: https://youtu.be/MD3kL0yQAYUWatch part 2 here: https://youtu.be/KtVhStCqH1A⸻

How do you actually build a sense of self with BPD?In this episode of The BPD Bunch, Xannie, Carys, Solène, André, and Katja continue the conversation on identity, this time focusing on what's helped us move toward a more stable sense of self. Still through the lens of the Alternative Model for Personality Disorders (AMPD), we're looking at identity as something you can actively shape over time.If you've ever felt empty, disconnected, or like you're constantly reinventing yourself… this is the part where we talk about what starts to change that.We talk about:• how chronic emptiness and dissociation connect to identity• relying on relationships or external validation to define who you are• the difference between emptiness and boredom (and why that matters)• finding purpose, values, and small anchors that make you feel more “real”• learning who you are without labeling yourself as “broken”• building identity through creativity, feedback, and lived experience• integrating different parts of yourself instead of rejecting them• why identity takes time and doesn't form all at onceThis is part of our Season 7 series where we're breaking BPD down in a more real, human way while also connecting it to newer ways of understanding personality.(In the first two episodes of the season, Dr. Carla Sharp, Dr. Frank Yeomans, and Dr. Alex Stein explained what the AMPD is, how it changes from the current categorical model, and how the BPD diagnosis is changing. )⸻

What does identity instability's actually feel like in BPD?In this episode of The BPD Bunch, Xannie, Carys, Solène, André, and Katja, start looking at identity through the lens of the Alternative Model for Personality Disorders (AMPD). It's a way of understanding BPD that focuses more on patterns and functioning, not just labels.If you've ever had that “who even am I?” moment… yeah. This is that episode.We talk about: • what it's like to feel like you don't have a solid sense of self • why you might feel like you don't know who you are • masking and becoming whoever you need to be to avoid rejection • losing yourself in relationships, jobs, or even your diagnosis • when BPD starts to feel like your whole identity • how identity struggles show up in everyday lifeThis is part of our Season 7 series where we're breaking BPD down in a more real, human way while also connecting it to newer ways of understanding personality.In the first two episodes of the season, Dr. Carla Sharp, Dr. Frank Yeomans, and Dr. Alex Stein explained what the AMPD is, how it changes from the current categorical model, and how the BPD diagnosis is changing. In case you missed it, here are the links:Watch part 1 here: https://youtu.be/MD3kL0yQAYUWatch part 2 here: https://youtu.be/KtVhStCqH1A⸻

So… what even counts as “BPD” anymore?Last week, we explored how the Alternative Model for Personality Disorders (AMPD) moves away from strict categories. This week, we're taking it further:What does BPD actually look like in this model, and do you even need the label at all?We break down the core of BPD through self and interpersonal functioning, how traits shape the “borderline” pattern, and why diagnoses like BPD and NPD might not be as separate as people think. If you've ever felt like the DSM didn't fully capture your experience, this might hit differently.This is Part 2 of a 2-part series.⸻Featuring:Dr. Carla Sharp — Clinical psychologist and Professor at the University of Houston. Director of the Developmental Psychopathology Lab, with a focus on personality disorders, mentalization, and adolescent development.Dr. Frank Yeomans — Clinical Professor of Psychiatry at Weill Cornell Medical College and Director of Training at the Personality Disorders Institute. Internationally recognized for his work in Transference-Focused Psychotherapy (TFP).Dr. Alex Stein — Clinical psychologist, researcher, and advocate known for her work on attachment patterns and “favorite person” relationships in BPD.⸻Subscribe to see what these traits actually look like from a lived experience perspective!

What if Borderline Personality Disorder isn't just a checklist of symptoms?In this episode of The BPD Bunch, we explore the Alternative Model for Personality Disorders (AMPD), a framework that shifts how we understand BPD from a set of categories to patterns of functioning, severity, and relationships.Joined by leading clinicians in the field, we break down what's changing, why it matters, and how this model could reshape diagnosis, treatment, and stigma.This is Part 1 of a 2-part series.⸻Featuring:Dr. Carla Sharp — Clinical psychologist and Professor at the University of Houston. Director of the Developmental Psychopathology Lab, with a focus on personality disorders, mentalization, and adolescent development.Dr. Frank Yeomans — Clinical Professor of Psychiatry at Weill Cornell Medical College and Director of Training at the Personality Disorders Institute. Internationally recognized for his work in Transference-Focused Psychotherapy (TFP).Dr. Alex Stein — Clinical psychologist, researcher, and advocate known for her work on attachment patterns and “favorite person” relationships in BPD.⸻Subscribe for Part 2 where we break down what BPD actually looks like under this model.

Synopsis:  As global military spending skyrockets and social programs face drastic cuts, a 50-year-old alternative emerges as a beacon of hope: the Lucas Plan, born from workers' determination to repurpose their skills for societal good.Make a tax deductible YEAR END DONATION and become a member go to LauraFlanders.org/donate. This show is made possible by you! Description [Original release date July 2025]: With the passage of the Republicans' “Big Beautiful Bill” and NATO allies pledging to more than double their spending on defense as a portion of all economic output, military spending around the world is soaring, while spending on meeting social needs and the climate crisis is on the chopping block. Governments often justify spending public money this way by saying it will create good jobs, but what if the workers themselves had a say? Fifty years ago, employees at Lucas Aerospace, a huge military contractor in the United Kingdom came up with an alternative plan. Their approach, known as the Lucas Plan, used the workers' same expertise, but directed production away from bombs, towards goods that actually help society. In this special episode, Laura heads to the UK to interview some of the original workers involved in the Lucas Plan and investigates what one senior government minister at the time called "one of the most remarkable exercises in all of British industrial history.” As she says, it's as relevant now as the day it was conceived.“What we're talking about is a poor economic choice that's being made to posture . . . and look like a big military power in a world that's growing increasingly unstable.” - Khem Rogaly“One of the things that the Lucas Plan has done is actually made it fairly clear to people that there are choices. You're given the impression that you have to make weapons. No, you don't. You're given the choice . . . The issue here is who controls technology and who should control technology, and should it be used to free people or should it be used to enslave people?” - Philip AsquithGuests:• Brian Salisbury: Former Lucas Aerospace Shop Steward• Philip Asquith: Former Lucas Aerospace Shop Steward• Hilary Wainwright: Co-Author, The Lucas Plan: A New Trade Unionism in the Making?; Co-Editor Red Pepper magazine• Khem Rogaly: Senior Research Fellow, Commonwealth; Author, A Lucas Plan for the Twenty First Century: From Asset Manager Arsenal to Green Industrial Strategy ADDITIONAL CREW: Stanley Arlidge - Episode Producer, Clementine Malpas, Tiger Nest FilmsSPECIAL THANKS: Karen Bell, Joe Guinan, Steve Schofield MUSIC CREDITS:  Thrum of Soil by Blue Dot Sessions and original sound design by Jeannie Hopper  RESOURCES:- Watch the episode released on YouTube July 11th 5pm ET; PBS World Channel July 13th, and on over 300 public stations across the country (check your listings, or search here via zipcode) and airing on community radio (check here to see if your station airs the show) & available as a podcast July 16th.-Related Podcast:  Uncut Conversation featuring Brian Salsibury, Former Lucas Aerospace Shop Steward-Related Podcast:  Uncut Conversation featuring Hilary Wainwright, Co-Author, The Lucas Plan: A New Trade Unionism in the Making?; Co-Editor Red Pepper magazineFull Episode Notes are located HERE.  Recommended book:• “The Lucas Plan: A New Trade Unionism in the Making?” by Hilary Wainwright and Dave Elliott, Learn More Related Laura Flanders Show Episodes:Democracy & Capitalism: A Failed Experiment?:  Watch / Listen:  Uncut Conversation - EpisodeCommunity Wealth Building: An Economic Reset:  Watch / Listen:  Uncut Conversation - EpisodeDollars and Democracy: Participatory Budgeting:  Watch / Listen:  Episode•  From Cleveland, OH to Preston, UK.  Community Wealth Building, Watch / Listen: Episode Related Articles and Resources:• A Lucas Plan For the Twenty First Century From Asset Manager Arsenal to Green Industrial Strategy, by Khern Rogsly, October 2024 - Common Welath•  The Lucas Plan the Way to an Alternative Security Strategy, by Khem Royally, December 11, 2024, Rethinking Security• UK to cut green levies on businesses in bid to reduce energy costs and boost manufacturing, by Jessica Elgot and Rob Davies, June 22, 2025, The Guardian•. Decarbonising and diversifying defense in the US and the UK:  A workers' enquiry for a Just Transition, Decarbonising-Defence.co.uk•  Wortley Hall, the Worker's Stately home, a member of the co-operative union•. US Defense Secretary Called Europe ‘Pathetic.”  Two BU Experts on Whether the Alliance Is Damaged, by Rich Barlow, March 27, 2025, Boston University Today•  ‘I will not protect you':  Trump Threatens to Abandon Nato Allies, Kaitlan Collins, October 11, 2024, CNN Laura Flanders and Friends Crew: Laura Flanders-Executive Producer, Writer; Sabrina Artel-Supervising Producer; Jeremiah Cothren-Senior Producer; Veronica Delgado-Video Editor, Janet Hernandez-Communications Director; Jeannie Hopper-Audio Director, Podcast & Radio Producer, Audio Editor, Sound Design, Narrator; Sarah Miller-Development Director, Nat Needham-Editor, Graphic Design emeritus; David Neuman-Senior Video Editor, and Rory O'Conner-Senior Consulting Producer. FOLLOW Laura Flanders and FriendsInstagram: https://www.instagram.com/lauraflandersandfriends/Blueky: https://bsky.app/profile/lfandfriends.bsky.socialFacebook: https://www.facebook.com/LauraFlandersAndFriends/Tiktok: https://www.tiktok.com/@lauraflandersandfriendsYouTube: https://www.youtube.com/channel/UCFLRxVeYcB1H7DbuYZQG-lgLinkedin: https://www.linkedin.com/company/lauraflandersandfriendsPatreon: https://www.patreon.com/lauraflandersandfriendsACCESSIBILITY - The broadcast edition of this episode is available with closed captioned by clicking here for our YouTube Channel

Dr. Robin Brody is back to tackle a critical gap in clinical training: narcissism and its devastating impact. We cut straight to the core, defining narcissism by its signature trait, entitlement, and exploring the clinical distinctions between grandiose, vulnerable, and malignant subtypes. The episode then dives into the flip side: narcissistic abuse. Learn to spot the confusing dynamics clients face, including performative empathy, denial of reality (often called gaslighting), trauma bonding through intermittent reinforcement, and the predictable cycle of idealization, devaluing, discard, and hoovering. Most crucially, we discuss the "sin" of inadequate provider training and the risk of how applying standard components of evidence-based treatment, like assertiveness skills, can tragically fail or even place survivors in danger.Dr. Robin Brody is an Assistant Professor of Psychiatry (Voluntary) at Weill Cornell Medicine and the founder of Dr. Robin Brody Psychological Services, a private practice specializing in the treatment of occupational trauma, PTSD, and couples therapy, and gender and sexually diverse individuals. Her work is driven by a deep commitment to helping trauma survivors, particularly those facing PTSD and moral injury.Her expertise and demonstrated passion center on treating trauma survivors, particularly those with PTSD and moral injury. In doing so, Dr. Brody has worked with diverse populations of civilians, veterans of all branches and eras, first responders, healthcare workers, and 9/11 survivors and responders across the diagnostic and demographic spectrum. Dr. Brody started and ran an EBP for PTSD program within the World Trade Center Mental Health Program, where she trained and supervised providers in PE and CPT. Before joining Mount Sinai's World Trade Center Mental Health Program, Dr. Brody served on the faculty at Weill Cornell Medicine. In that capacity, Dr. Brody oversaw Weill Cornell's Military Families Wellness Center and worked within the Program for Anxiety and Traumatic Stress Studies (PATSS), where she was a co-investigator on numerous clinical research studies involving the treatment of PTSD, particularly among frontline healthcare workers amidst the COVID-19 pandemic. In all her efforts, Dr. Brody is committed to increasing access to, and training, in evidence-based treatments, especially for PTSD. Dr. Brody's research interests include PTSD treatment innovation and the role of shame, stigma, and identity in trauma recovery.Resources mentioned in this episode: DSM-5 Alternative Model of Personality Disorders It's Not You, Dr. Ramani Durvasula Calls-to-action: Utilize Diagnostic Frameworks: Look into the DSM-5 Alternative Model of Personality Disorders as a useful framework for understanding healthy personality functioning and personality disorders, including narcissism.Obtain additional training on NPD and narcissistic abuseSubscribe to the Practical for Your Practice PodcastSubscribe to The Center for Deployment Psychology Monthly Email Leave us a question or comment on Speakpipe

September 19, 2025- Assemblymember Emily Gallagher, a Brooklyn Democrat, and state Sen. Jabari Brisport, a Brooklyn Democrat, weigh in on an affordable housing development in Brooklyn that isn't producing the promised units and make the case for a different model of building affordable units.

Laurie Sossa is the Founder of SBC Global Barter network. Her SBC platform consists of thousands of businesses that subscribe and reciprocate with networks with 50,000 businesses that buy and sell with the cashless currency. Laurie and her SBC Network received a proclamation and resolution from the state of Georgia recognizing the economic impact, mentoring and good will helping women and minority businesses, nonprofits and small business owners by bringing spending power through this kind of network.  Laurie's unique expertise and vast global network of partners, opens a world of resources that generate growth, preserve capital, create new revenue streams, form strategic alliances and bring value-add for business growth. [Southern Barter Exchange – Website] • [SBC Global Barter – Website]  

In this ToxChats© episode, we interview Dr. Chris Christou, Director of Preclinical Imaging and Research Laboratories at the South Australian Health and Medical Research Institute. Dr. Christou discusses the history of sheep as a preclinical species for medical device testing, novel groundbreaking neurological disease models, and the use of sheep as an alternative model in general toxicology studies. Critical regulatory standards and international guidelines are discussed to ensure successful submissions with the US Food and Drug Administration, the Australia Therapeutic Goods Administration, and the Australia New Zealand Therapeutic Products Agency.

"Within Rajasthan's Raika culture, camels are raised in a system that's cruelty free - the calves are not separated from their mothers, camels walk around and choose their own diets and have a close relationship with humans. It's an alternative model of livestock and food production that has great value. The Raika demonstrate a way of keeping animals that's in tune with the environment and has high animal welfare standards. It should be a model for the rest of the world. Slowly, we are getting to the stage where people are recognising this. Modern India's thinking about livestock needs to be decolonised because India's traditional livestock keeping systems are a treasure. There's enormous heritage value in them and this intangible heritage also creates wealth and has a lot of commercial potential. What's missing is an appreciation of the value of this heritage. I don't regret that I've been here for the last 30 years." - Ilse Kohler-Rollefson, author, Camel Karma talks to Manjula Narayan about her work with the camel herders of Rajasthan, the great health benefits of milk from free-range camels, and why sustainable methods of livestock farming make more sense.

The Extraordinary Original Divine Mirror Rodney Diamond stops by to have a chat.  Find Rodney on IG @8thAveAdult    

The first episode of 2023 is starting off with one of my favorite people, Anastasia Eve Sabil! Every so often I connect with a model/client on a Spiritual level and this is THAT type of vibe. Anastasia is more of an Alternative Model, but during our shoot discovered that she appreciates attention given to her feet. Join us as we discuss everything from her sticking her tongue out, her being part of the Lifestyle, emotional nudity, penis pictures with bow-ties, having an orgasm without being touched, a new TV show, and so much more! Check us out wherever you listen to your favorite podcasts!!

This episode is also available as a blog post: https://thecitylife.org/2022/10/02/moma-presents-the-first-exhibition-exclusively-devoted-to-just-above-midtown-the-new-york-city-gallery-and-black-space-that-championed-an-alternative-model-of-art-making-during-the-1970s-and-1980s/ --- Send in a voice message: https://anchor.fm/citylifeorg/message Support this podcast: https://anchor.fm/citylifeorg/support

The discussion of platform or gig economy has been a very worldwide issue nowadays. Martijn Arets, the founder of GigCV, tries to address the most profound problems faced by gig workers around the globe. What is GigCV? How does it work using data portability? What is the most appropriate governance which can benefit all actors? Watch Suci Lestari Yuana's talk with Martijn Arets in Podcast Hubungan internasional Ep. 47! _________________ Music:  Judul : [FREE FOR PROFIT] "Lucky" Happy Groovy background music/montage for vlogs no copyright - prod. OBI Channel : OBI  Link : https://www.youtube.com/watch?v=V1Y6whi9r2w  Track: Percussion And Stomps [Sports Music] by MokkaMusic / Take A Step https://youtu.be/9s_c1gYpyk8  Music provided by "MokkaMusic" channel and https://inaudio.org _________________ YouTube: https://youtu.be/MuiAk72f4_4

Who is Sabrina Night? She's a porn star, an Alternative Model, a dominatrix, a content creator as well as being an ambassador for a new live cam show site. We spoke about how she got in the adult industry and some of the most memorable movies she has shot as well as giving us some tips on fisting. It was such a fun podcast to record and I can't wait for you guys to listen to it. Follow Sabrina: https://linktr.ee/CumAndGetMe Follow Angel Long: Instagram - https://www.instagram.com/theangellong/ Twitter - https://twitter.com/Angel_long Website - http://angellongfans.com/

In this episode, I interview Baltimore-based alternative model Minnie Soles.  If you enjoy the podcast, would you please consider leaving a short review on Apple Podcasts/iTunes? It really makes a difference and it's always nice to read kind words.Follow us on Twitter and  InstagramBe sure to check out our other podcasts:Mastermind Team's Robcast - Mastermind Team's Robcast is an irreverent and hilarious podcast covering all things pop culture and weird news. Let's Watch It Again - Let's Watch It Again is a movie review podcast from MTR The Network.★ Support this podcast ★

Warning:This is the Completely Inappropriate Podcast We will be Inappropriate...we are NOT experts. We finally have a guest we've been trying to get since the beginning. A guest that launched our first "completely inappropriate investigates". The beautiful, the talented, the lovely, Rozzmonster!It all begins with a simple hello and the story how Rozzmonster got her name. Followed by a quick walk through of her journey into modeling.Rozzmonster shares with us her biggest hobbies along with what's her poison. There's a story to that, too.We try to squeeze in as much Rozzmonster as we can in an hour. But don't worry, we continue this conversation on the next episode. Listen to this episode so you won't get lost on the next. Believe us, she's worth the while

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.03.234567v1?rss=1 Authors: Benvenutti, R., Gallas-Lopes, M., Sachett, A., Marcon, M., Strogulski, N. R., Reis, C. G., Chitolina, R., Piato, A., Herrmann, A. P. Abstract: Background and Purpose: Schizophrenia pathophysiology has been associated with dopaminergic hyperactivity, loss of parvalbumin-positive GABAergic interneurons, NMDA receptor hypofunction, and redox dysregulation. Most behavioral assays and animal models to study this condition were developed in rodents, leaving room for species-specific biases that could be avoided by cross-species approaches. As MK-801 and amphetamine are largely used in mice and rats to mimic schizophrenia features, this study aimed to investigate the effects of these drugs in zebrafish. Experimental Approach: Adult zebrafish were exposed to MK-801 (1, 5, and 10 uM) or amphetamine (0.625, 2.5, and 10 mg.L-1) and observed in paradigms of locomotor activity and social behavior. Oxidative parameters relevant to schizophrenia were quantified in brain tissue. Key Results: MK-801 disrupted social interaction, an effect that resembles the negative symptoms of schizophrenia. It also altered locomotion in a context-dependent manner, with hyperactivity when fish were tested in the presence of social cues and hypoactivity when tested alone. On the other hand, exposure to amphetamine was devoid of effects on locomotion and social behavior, while increased lipid peroxidation in the brain. Conclusion and Implications: Key outcomes induced by MK-801 in rodents were replicated in zebrafish, which suggests this species is suitable as an alternative model animal to study psychotic disorders. More studies are necessary to further develop preclinical paradigms with this species and ultimately optimize the screening of potential novel treatments. Copy rights belong to original authors. Visit the link for more info

Is higher education broken? Maybe a four-year degree followed by graduate school and six figures of debt makes sense for some professions like doctors and lawyers, but what about for the rest of us?Frequent listeners may know that Jeremy spent a bit of exile during the early months of the pandemic in Ohio, which made us really want to spotlight some of the state’s interesting entrepreneurial stories. Enter Dwight Heckelman, who founded Columbus, Ohio-based Groove U, which offers two-year diplomas in Music Industry Entrepreneurship in focal areas like Music Business, Live Sound, Interactive, and more. Jeremy had a chance to sit down with Dwight to talk about ways in which higher education must evolve, what programs should really be judged on, and the universal value of entrepreneurial skills. As always, we welcome your feedback. Please make sure to subscribe, rate, and review on Apple Podcasts, Spotify, Stitcher, and Google Play.

COVID-19 isn't going anywhere in the near future, yet all but 3 law schools and only 8% of universities and colleges have announced they will be entirely remote for fall 2020. What is the most recent update, and is there a middle ground that can be reached to decrease on-campus density so that the likelihood of cluster outbreaks is significantly reduced? You can also listen on YouTube https://youtu.be/E1u9T65OnTE or Apple Podcasts https://podcasts.apple.com/us/podcast/spivey-consulting-law-school-admissions-podcast/id1477090223 And check out our free law school rankings tool, My Rank https://myrankbyspivey.com/

Gravity Ventures is a capital funding group that aims to help start-up tech companies. Today I am with Trey Buck, managing director of Gravity Ventures and he talks about how Gravity Ventures aims to provide opportunities for local investing companies and for angel investors. In which, with the aid of the funding, the two come together, thus offsetting risks for start-up companies of doing it solo by being provided with capital from angel investors. In a way, these two different entities benefit as they become part of one another through the funding.Topics in this episodeThe process of how start-up companies can obtain investment from Gravity Ventures.What investors want to see when start-up companies pitch to them.Examples of what they look for in the due diligence processThe diverse portfolio of companies they have invested in.Overview of Fund Four for the investment groupImportance of product-market awareness and knowing your competitors.How to stand out in a product pitch to make investors invest.Contact detailsWebsite – www.gravityventures.comEmail – trey.buck@gravityventuresLinkedIn - https://www.linkedin.com/mwlite/company/gravity-ventures-llcReach Ocean Clean Up thru www.oceancleanup.com

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.04.24.058917v1?rss=1 Authors: Chyba, M., Kotas, J., Beringue, V., Eblen, C., Igel-Egalon, A., Kravchenko, Y., Rezaei, H. Abstract: Prion assemblies responsible for transmissible spongiform encephalopathies grow in the form of linear amyloid fibrils. Traditional models for prion growth and tissue-spreading have relied upon the assumption that propagation is based on the process of fragmentation, wherein an assembly literally breaks in two, creating additional templating interfaces. Recent experimental data shows that PrPSc assemblies are in detailed balance with an elementary oligomeric building block called suPrP. In the present work we compare the dynamics of the canonical model of induced fragmentation to the model of PrPSc assemblies in detailed balance with suPrP. The model is a dynamical system describing the populations of fibrils of varying lengths as a function of time; we analyze the system via both analytical and numerical techniques. We demonstrate that the detailed balance between suPrP and PrPSc model can equivalently replace the induced-fragmentation model. This equivalence opens a new opportunity in an optimal control problem. Copy rights belong to original authors. Visit the link for more info

Amber Eve is a car enthusiast, pro self-growth, determined, ambitious and a self-proclaimed Alpha Female as being a long time listener of the show!

She was staying at an AirBNB, and it was a little bit of an unfortunate experience that she had with another photographer and colleague. While he was off doing another shoot at a different AirBNB, she took a series of striking and emotional self-portraits in this tiny room, and I think we can all agree he made a big mistake. Who knows if the shot would have been captured the same way though..... Instagram @Sammyanne.creative Youtube video of the show https://www.youtube.com/watch?v=QEzgYCSF7hk

This week I chat to the wonderful Valen Vain. Valen is a male model as well as a burlesque performer, and also an events organiser. We talked about his journey into modelling which started with Bizarre magazine. As he says himself he is excessively flamboyant, a pole dancer, compere, boylesque artist and comedian. Plus owner of cult of Vain Events, inventor of K.E.N and frontman of Sordid Lies! But when I chatted to him he's a bloody lovely guy, so effortless to talk to and very open about all his talents. So pleased to have him on the show. Plus currently holds these titles to:Alternative Model of the Year Male Winner 2016 Sexy Compere Flirtacious. I've got the best! Thanks Valen!!  You can find Valen here: Facebook: Valen Vain Twitter: Valen Vain Instagram: Valen Vain IMDb: Valen Vain

Cannabis as the cause of illness is our topic as Vivian McPeak speaks with Alternative Model, Cannabis Enthusiast and Activist Damsel W. Dank. Damsel suffered from arsenic poisoning from ingesting bad cannabis and she explains how she has handle treating the problem which Vivian knows all too well based on his own personal health. She takes us through how she first realized her issues and her mission to treat it.

Produced by Isabeau Schubert (Bay FM, Byron Bay) How does attending a Steiner School shape someone's understanding of the world? Isabeau Schubert should have a good idea, as she is an alumnus. In Steiner Education: An Alternative Model Isabeau talks with parents, students and teachers to ultimately ask whether Steiner education has a place in contemporary Australia. For more information, visit https://www.cbaa.org.au/article/alternative-education-steiner-approach-bayfm-byron-bay

Produced by Isabeau Schubert (Bay FM, Byron Bay) How does attending a Steiner School shape someone's understanding of the world? Isabeau Schubert should have a good idea, as she is an alumnus. In Steiner Education: An Alternative Model Isabeau talks with parents, students and teachers to ultimately ask whether Steiner education has a place in contemporary Australia. For more information, visit https://www.cbaa.org.au/article/alternative-education-steiner-approach-bayfm-byron-bay

This week Jed is joined by co-host of the Lament Configuration podcast, Tromette, Alternative Model, Actress and Graphic Designer... Ria Fend! Though Ria tries her best to make the whole episode horror-centric, Jed makes sure there are suggestions for everybody's taste. As long as that taste is underrated and possibly unusual! You can get in touch with Jed on twitter @jedshepherd and Ria @riafend.

Frustrated that a promising therapy for a rare cancer was sitting in a freezer due to the lack of a relatively modest amount of funding, author Alexander Masters helped lead a campaign to crowd-fund a clinical trial: the result, iCancer.org.uk. The money required was indeed raised by a wealthy individual primarily, in return for being in the trial. At DPharm Europe, Pfizer's Craig Lipset interviewed on stage Alexander to share his story. We are delighted to present the journey and latest updates on PharmaTalk Radio.  The story of the formation of iCancer.org.uk and the Oncolytic Virus FundAn alternative way to make clinical trials more accessibleEthical and moral issuesA possible disruptive and sustainable model for other neglected medicines The next DPharm: Disruptive Innovations to Advance Clinical Trials event takes place September 20-21 in Boston. DPharm Europe is scheduled for February 8-9, 2017 in London. For more information about these events or our Immuno-Oncology events, visit, www.theconferenceforum.org. Producer: Valerie Bowling Executive Director, Conference Forum & Pharma Talk Radio Guest Host: Craig Lipset, MBA Head of Clinical Innovation, R&D,Pfizer Guest: Alexander Masters Author, Medical Campaigner and Co-Founder,iCancer.org.uk    

In this Episode our hosts Diego and Hector discuss Bachelor parties vs. Bachelorette Parties. We then are joined by the lovely HOT ROD HEATHER where we talk Fitness, being an Alternative Model, our love of Animals, and various races we have and will Participate in. and so much more. Afterwards our hosts go over their 4th of July Adventures. Does one of the Hosts get some action? only one way to find out!

In this Episode our hosts Diego and Hector discuss Bachelor parties vs. Bachelorette Parties. We then are joined by the lovely HOT ROD HEATHER where we talk Fitness, being an Alternative Model, our love of Animals, and various races we have and will Participate in. and so much more. Afterwards our hosts go over their 4th of July Adventures. Does one of the Hosts get some action? only one way to find out!

It's a night of Canadians on MTAZS radio! Alternative model/musician/entrepreneur Tara Mason will be my guest tonight.http://www.myspace.com/skate4cancerhttp://www.myspace.com/taramasonhttp://www.myspace.com/morethanazodiacsign

It's a night of Canadians on MTAZS radio! Alternative model/musician/entrepreneur Tara Mason will be my guest tonight.http://www.myspace.com/skate4cancerhttp://www.myspace.com/taramasonhttp://www.myspace.com/morethanazodiacsign