Podcasts about Prion

Gray's Youtube: https://www.youtube.com/channel/UC2NfSPGZ5OFcek6Baw3iQQw SuS Records: https://www.youtube.com/@SusRecordsCEO Jared's Youtube Channel: https://www.youtube.com/@ComicsLeague Jared's Podcast: https://open.spotify.com/show/3jv6I2edZ8lpc02gJEHw3e?si=cb5f48a6f8d84add Stork's Podcast: https://besottedgeek.podbean.com/   YouTube: https://www.youtube.com/@WeirdScienceComics Listen to the Spotlight Podcast by signing up to our Patreon - https://www.patreon.com/weirdscience   0:00:00 - Intro 0:17:48 - Superman #40 0:35:38 - Action Comics #1100 1:09:01 - The Peril of the Brutal Dark: An Ezra Cain Mystery #6 1:43:41 - Detective Comics #1111 2:28:18 - Green Lantern #37 2:51:30 - Flash #35 3:20:01 - Batwoman #5 3:49:38 - New Titans #37 4:41:12 - Next Week's Books     FOLLOW WEIRD SCIENCE COMICS Twitter:  https://twitter.com/WeirdScienceDC  Patreon: https://www.patreon.com/weirdscience DC Comics Review Site: https://bit.ly/WeirdScienceDC Marvel Review Site: https://bit.ly/WeirdScienceMarvel   SUBSCRIBE TO WEIRD SCIENCE COMIC PODCASTS:  DC Comics Podcast iTunes - https://apple.co/47jNeme Spotify - https://spoti.fi/2XzDALI Stitcher - https://bit.ly/45XPtKS   Marvel Comics Podcast iTunes - https://apple.co/3u1xxSh Spotify - https://spoti.fi/3QJFAfe Pandora - https://bit.ly/3Qq5cwd

Jace and Rocky break down all 14 DC releases for the week of July 22, 2026. Green Lantern #37 shows Kyle Rayner and Odyssey both learning you should never feed the trolls when Odyssey's online feud spills into the real world. Harley Quinn #64 reveals the mastermind behind the Harley Quinn Revenge Squad and proves Harley is her own worst enemy. Superman #40 uses Superboy-Prime to show that even after redemption begins, the consequences of your past never disappear. Justice League Unlimited #21 has the League finally turn the tables on Brainiac Queen with a surprise plan from Red Tornado and the Atom, while Batman and Lex learn they have something in common regarding the consequences of the Omega Tournament. Superman: Father of Tomorrow #3 shows Lex Luthor's decision to abandon science for sorcery perfectly highlighting the series' central debate over power and responsibility. Absolute Wonder Woman #22 has Barbara Minerva willingly surrender herself to Urzkartaga, but her true objective remains a mystery. The Peril of the Brutal Dark: An Ezra Kane Mystery #6 sends Ezra Kane into the skies in a biplane for a cinematic showdown with Nazi automatons that delivers the pulp-adventure ending the series promised. Swamp Thing (1989) #4 gives Swamp Thing and Abigail a hopeful ending by leaving multiversal versions of themselves behind. Dark Knights of Steel: Heir to the Sea #1 highlights Arthur Curry taking Superman's place as the extraordinary child raised by Jonathan and Martha Kent. Absolute Superman #21 delivers a perfect balance of action and character as Superman shows just how much he cares about the people who can slip through the cracks as much as he cares about world-ending threats like King Shazam. Zatanna #4 has Zatanna learn firsthand from previous Prime Magi that the role isn't what she thought it was. The Flash #35 has Wally learn that with enough data he can stop anything bad from occurring in Central City—but should he be watching everyone? And what happens when he tries to expand that to Metropolis? Action Comics #1100 ends its time-travel story with Superboy coming face-to-face with his older self, while a surprise return from a classic Superman villain leads into the next big event for the Superman Family. Detective Comics #1111 has Batman's investigation uncover the terrifying truth behind the force manipulating generations of the Prion family, and his vow to save them proves the lasting impact Prion had during his brief time with Batman. They also give a rundown of this week's collected editions, reprints and facsimile releases. As always, all books are ranked from top to bottom and each host gives a Book of the Week pick.

In this lab minute, Dr. Stacey Clardy discusses human prion disease. 

In this lab minute, Dr. Stacey Clardy discusses human prion disease. 

Jace and Rocky break down all 17 DC releases for the week of June 24, 2026. They discuss Detective Comics #1100, where Batman, Green Arrow and Black Canary continue investigating Prion's past while the mystery surrounding the young assassin tied to his grave becomes more complicated. Bizarro Year None #2 follows Perry White and Jimmy Olsen as they try to understand the strange rules of Bizarro's square world as the series begins framing this as a distorted Bizarro origin story. Harley Quinn #63 continues Harley's darker current direction as the monochromatic infection and her fractured emotional state push her further from the zanier version of the character. Absolute Superman #20 returns with a massive battle against King Shazam as Superman, Steel and Hawkman are forced to confront whether overwhelming power can be stopped without sacrificing innocent lives. Green Lantern #36 reconnects Kyle Rayner and Jade while Odyssey's identity and past remain in question. Gotham Academy: First Year #5 follows Olive Silverlock's nightmare as it forces her to confront fears about her mother's legacy while Batman and the Gotham Academy cast move closer to the final issue. Absolute Wonder Woman #21 focuses on Absolute Wonder Woman's time in Hell separating her from Barbara Minerva, whose captivity and connection to a dangerous feline god open new questions about her future. The Peril of the Brutal Dark: An Ezra Cain Mystery #5 sees Ezra Cain's pulp adventure escalate into a Nazi-blimp action sequence that leans hard into the series' darker Indiana Jones energy. Flash #34 has Ryan North explain Flash's new precognitive ability through data, speed and probability while keeping the story light, accessible and emotionally grounded. Superman #39 pushes Superboy-Prime through multiple comic-book realities as Manchester Black tests whether he has truly changed, while Dan Mora shifts art styles to match each world. Superman: Father of Tomorrow #2 sees Jor-El refuse to let Kryptonian technology be used for weapons while Lex Luthor secretly moves forward with non-lethal weapon development, and the issue brings in Klarion and John Constantine as magic emerges as a weakness for this version of Superman. Wonder Woman #34 brings Wonder War to Diana's confrontation with Matriarch, as the fight centers on whether Wonder Woman's willpower can overcome a Green Lantern ring that Matriarch has spent years forcing to obey her. The issue also ends with Diana making a drastic choice involving the God Killer sword. Justice League Unlimited #20 has Wonder Woman nearly reach Brainiac Queen before Lex Luthor's arrogance and his use of Warp ruin the Justice League's chance to turn her, leaving her missing and possibly setting up a "Cyber Earth" timeline. Swamp Thing 1989 #3 brings Rick Veitch's long-delayed story to its most epic chapter yet, with Swamp Thing existing across different points in DC history and Darkseid appearing in a way that fits the elemental scope of the story. Zatanna #3 pits Zatanna against Agent Di Manes, whose power of quietude suppresses her voice and directly attacks the way she uses magic, while the story also involves Elodi and a muse spirit tied to a dead singer. Summer of Supergirl Special #1 continues from Lobo #4, putting Supergirl and Lobo on trial while Crush, Krypto and Dawg get pulled into the chaos, and the special also includes a Supergirl/Mary Marvel team-up plus a Mark Waid story connecting different versions of Supergirl's history. Justice League: Dream Girls #4 concludes with the Justice League apologizing to Galaxy and giving her mission leader rank, while Dreamer chooses not to join the League yet because she still needs to understand her powers on her own. They also give a rundown of this week's collected editions, reprints and facsimile releases. As always, all books are ranked from top to bottom and each host gives a Book of the Week pick.

“The Malicarn. The sixteenth winter in the reign of Queen Hannah. At night the master would invite the journeymen and apprentices to supper with his family, and that is where Buck first heard real tales of the old wars. How there used to be hundreds of wizards, how the old king Prion, himself once just a lowly sheepherder, became the one to unite them against the Dark Mages, how the many men of the Malicarn were called to fight.”

Dr. Gregg Day and Drs. Sonia Vallabh and Eric Minikel discuss scientific insights and the future of prion disease treatment, highlighting the importance of early diagnosis, personalized medicine, and hope for affected families.  Learn about the clinical trial.   Learn more about the Prion Alliance.  Show transcript:  Dr. Gregg Day: This is Gregg Day with Neurology Minute. I've just been speaking with Eric Minikel and Sonia Vallabh, a husband and wife team at the heart of the PRiSM trial, a first-in-human study of a prion protein-lowering, divalent, small-interfering RNA for patients with symptomatic prion disease. Eric and Sonia, could you provide us with a brief overview of the PRiSM trial and what this first-in-human study seeks to accomplish? Dr. Eric Minikel: The PRiSM trial is testing a short interfering RNA designed to bind the RNA that encodes the prion protein. That is the protein that causes Prion disease. We are at the heart of what causes this disease. Through doing this, we hope to make prion disease a treatable and preventable condition. We both want to stabilize symptomatic patients and prevent the disease in people who are at genetic risk. This is a personal mission for us. Sonia is a carrier of a prion disease mutation that she inherited from her mother who died of prion disease, and we, along the way, aspire to be a different kind of sponsor. We want to create our own clinical data that are shareable learnings for the entire field. Dr. Gregg Day: This is Gregg Day with Neurology Minute. Thanks for listening.

Dr. Gregg Day talks with Drs. Sonia Vallabh and Eric Minikel about scientific insights and the future of prion disease treatment, highlighting the importance of early diagnosis, personalized medicine, and hope for affected families.  Learn about the clinical trial.   Learn more about the Prion Alliance.  Disclosures can be found at Neurology.org.  

Jace and Rocky break down all the DC Comics releases for the week of April 22, 2026, covering 10 books with a wide range of reactions from solid entertainment to standout highlights. Superman #37 features a meta-driven Superboy Prime navigating life in Metropolis while grappling with his past and a surprising encounter with Witchfire, Flash #32 introduces a dangerous viral stunt app pushing Wally West to his limits while juggling family life, and Detective Comics #1108 continues Tom Taylor's grounded mystery with Bruce teaming with Green Arrow and Black Canary while uncovering secrets tied to Prion's legacy. Absolute Flash #14 explores the Mirror Master storyline with Wally and Linda trapped in the mirror dimension and a deal involving Ray Palmer, while Absolute Wonder Woman #19 continues Diana's mythic journey with high-stakes magical elements. Green Lantern #34 sets up future developments with Hal Jordan and Kyle Rayner while introducing the mysterious Toby Y2K, and Justice League Unlimited #18 examines the controversial decision to grant villains amnesty in the face of larger threats. Harley Quinn #61 leans into the split between Harley's personalities with the Bat-Quinn concept, while Harley & Ivy: Life and Crimes #5 slows things down with character work at Ma Hunkel's home and a Clayface cliffhanger. The Brutal Dark #3 builds its noir mystery around Ezra Kane with deeper connections to the museum heist and missing persons case. The episode also includes discussion of industry news, including layoffs and broader market trends, along with thoughts on speculation around current titles. As always, Jace and Rocky run down reprints, facsimiles, and collected editions, rank every book from the week, and each give their pick for Book of the Week.

"EL OSCURO SECRETO DEL CELIBATO| PATRIARCA ANDRÉS TIRADO"https://youtu.be/6sQDrnNkSu4MATERIAL DE INVESTIGACIÓNhttps://drive.google.com/drive/folders/1RrWSGrpS6T1XgoMLELi5iBYyqX-PKM9W?usp=sharingNATIONAL GEOGRAPHIC HISTORIA - ¿Cuándo y por qué se estableció el celibato obligatorio para los eclesiásticos? - https://historia.nationalgeographic.com.es/a/cuando-y-por-que-se-establecio-celibato-obligatorio-para-eclesiasticos_24520Bibliographía:Oxtord Dictionary ot Popes;H.C. Lea History of SacerdotalCelibacy in the Christian Church 1957;E. Schillebeeckx The Church with a Human Face 1985;J. McSorley Outline History of the Church by Centuries 1957;F.A.Foy (Ed.) 1990 CatholicAlmanac 1989;F.A.Foy (Ed.) 1990 CatholicAlmanac 1989;D.L. Carmody The Double Cross - Ordination, Abortion and Catholic Feminism 1986;P.K Jewtt The Ordination of Women 1980;A.F. Ide God's Girls - Ordination of Women in the Early Christian & Gnostic Churches 1986;E. Schüssler Fiorenza In Memory of Her 1984;P. DeRosa Vicars of Christ 1988.The Bad Popes, Chamberlin, E.R., Sutton History Classics, 1969 / Dorset; New Ed edition 2003.The Pope Encyclopedia: An A to Z of the Holy See , Matthew Bunson, Crown Trade Paperbacks, New York, 1995.The Papacy, Bernhard Schimmelpfennig, Columbia University Press, New York, 1984.Le douzième chiffre c'est le zéro, F. Ake. Calatorao University, Cimeria, 2018Lives of the Popes, Richard P. McBrien, Harper Collins, San Francisco, 1997.Papal Genealogy, George L. Williams, McFarland& Co., Jefferson, North Carolina, 1998.Sex Lives of the Popes, Nigel Cawthorne, Prion, London, 1996.Popes and Anti-Popes, John Wilcock, Xlibris Corporation, 2005.La véritable histoire des papes, Jean Mathieu-Rosay, Grancher, Paris, 1991.Papas sexualmente activoshttps://es.wikipedia.org/wiki/Anexo:Papas_sexualmente_activosDONACIONES: PAYPAL: https://paypal.me/OBISPOANDRESTIRADOFACEBOOK PAGINAShttps://www.facebook.com/profile.php?id=100063452115636LINKEDINhttps://www.linkedin.com/in/arzobispo-andres-tirado-perez-b1b4a89a/CANAL DE WHATSAAP EXORCISTA PATRIARCA ANDRES TIRADO https://whatsapp.com/channel/0029VaY3VsHCxoAthlCKuA3tINSTAGRAMhttps://www.instagram.com/obispoandrestirado/?hl=es-laTWITTERhttps://twitter.com/PADREANDRESYOUTUBEhttps://www.youtube.com/user/CONGREGACIONCSI/videosTIK TOK OBISPO ANDRÉS TIRADOhttps://www.tiktok.com/@obispoandrestirado?is_from_webapp=1&sender_device=pcPodcast Amazon: https://www.amazon.in/s?k=ARZOBISPO+ANDRES+TIRADO&ref=dp_byline_sr_all_1Podcast Spotify:https://open.spotify.com/show/69Lpc3zoOkp0FoFSp6USM2Congregación Sacerdotal Internacional – Católicos IndependientesNO representamos a la Iglesia Católica Apostólica RomanaWEB: www.congregacionsacerdotal.orgE-mail padreandrestirado@gmail.com

Our Editor-in-Chief, Elena Becker-Barroso, speaks with Inga Zerr (DZNE, Göttingen, Germany) and Simon Mead (UCL London, UK) about the latest advances in prion diseases. In collaboration with other experts, Zerr and Mead have authored a Series in the journal that covers the genetic factors behind these diseases, and new diagnostic and prognostic biomarkers.Click here to read the full articles:https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00451-X/fulltexthttps://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00406-5/fulltextMedical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Theranostics. You can visit https://www.thelancet.com/medical-imaging-theranostics to learn more.Continue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

If a Prion does not exist what has the goverment been lying about for the past 50 years. I am talking scrapie in sheep, BSE in cattle and CWD in cervids.

Victoria kicks things off this week with the terrifying topic of Prion diseases. These bizarre infections can take years to manifest, are incurable, and can turn your brain into a sponge. Charming. Kirk is up next with a ghost story for this spooky season. Science wins out over superstition and in the end it ends up being a tale of how infrasound can affect human physiology and may be to blame for many ghost reports. Rachel rounds out the show with a creature feature on the most venomous and possibly most painful animal in the world, the Stonefish. Join us weekly for more strange nature. Our supporters on Patreon get every episode ad-free!  Support us: patreon.com/strangebynature Email us: contact@strangebynaturepodcast.com Visit us at: strangebynaturepodcast.com  where you can sign up for our episode emails.

As our 10th season comes to a close we review all the stories and non-stories from trade week and make some vague projections about the year ahead. Thanks for listening in 2025, we'll be back in 2026, but between now and then look out for a special episode or two where we dissect Dwayne Russell's novel Killing For Sport. 

This week on the Super Fun Time Trivia Podcast, we discuss the best colour for anal beads, Noah's Bestiality Bang Boat, and what happens when you drop that fragrant bag. Also, don't eat human meat guys, no matter how delicious it is.   Music Round: Me First And The Gimmie Gimmies Patreon: Super Fun Time Trivia Website: superfuntimetrivia.com Facebook: superfuntimetrivia Instagram: superfuntimetrivia Twitter: @sftimetrivia Email: superfuntimetrivia@gmail.com Intro Music By David Dino White. Welcome to Super Fun Time Trivia: The known universe's only live improv comedy trivia podcast.  

Neuropsychiatrist Brian Appleby, MD, discusses prion diseases, including Creutzfeldt-Jakob disease, and the groundbreaking research and clinical trials at University Hospitals aimed at better understanding these rare but fatal neurodegenerative conditions. Learn more about Brian Appleby, MD Learn more about the University Hospitals Research & Education Institute Follow Us on Social:      

In January, 1997, David Nierenberg was a physician at Dartmouth‐Hitchcock Medical Center, specializing in toxicology. Chemist Karen Wetterhahn was placed in his care. When she arrived at the hospital, Karen was slurring her speech and having difficulty balancing and with coordination. What David soon learned was that her symptoms were all due to a few tiny drops of a compound called dimethylmercury. Today's episode focuses on two lab accidents that had a profound impact on research communities, and that inspired changes that have likely saved the lives of scientists and other workers since. The first story is that of Karen Wetterhahn who, in the 1990s was a professor of chemistry at Dartmouth College whose lab focused on heavy metal toxicity. The other story is about fatal prion protein exposures in France that led to a temporary moratorium in 2021. Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!Links to the Tiny Show and Tell stories are here and here. All Tiny Matters transcripts and references are available here.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Kickstarter here: https://www.kickstarter.com/projects/garycolton/how-it-falls-apart-an-immersive-dystopian-thrillerIn this episode, we discuss various pressing global issues, including the potential for World War III, the societal impacts of pandemics, and the mysteries surrounding prion diseases and the disappearance of the racehorse Shergar. We also delve into the portrayal of zombies in media, the psychological effects of torture, and the role of special forces in modern conflicts. In this conversation, the hosts delve into the authenticity of war stories, the rise of operator literature, and the psychological profiles of serial killers, particularly focusing on Andre Chikatilo. They explore the nature of evil, the complexities of human behavior, and the impact of childhood trauma on adult actions. The discussion highlights the intricate relationship between personal history and criminal behavior, emphasizing the need for understanding rather than mere condemnation. In this conversation, the hosts delve into the dark world of serial killers, focusing on specific cases such as Dean Corll and Aileen Wuornos. Lastly, we discuss the innocence of the victims, the investigative oversights that allowed these killers to operate, and the psychological aspects of confession and manipulation. Descent Into Darkness YT Channel - https://www.youtube.com/@DiD86Dark Finds Podcast IG - https://www.instagram.com/darkfindspodcast/Patreon - https://www.patreon.com/darkfindspodcast/membershipDark Finds IG - https://www.instagram.com/dark.finds/Dark Finds YouTube Channel for more dark long-form content - https://www.youtube.com/@DarkFindsChannelDark Finds book - https://amzn.eu/d/3VHPOTjDark Finds website - www.darkfindsmedia.comTakeawaysThe threat of global conflict is more pronounced than ever.Prion diseases are a serious health concern with no cure.The mystery of Shergar's disappearance remains unsolved.Zombies in media often blur the lines between fiction and reality.Torture can lead to false confessions and severe psychological consequences.Special forces operate under extreme pressure and secrecy.The portrayal of military operations in media can be misleading.Public perception of global events is heavily influenced by social media.Understanding the origins of diseases can help prevent future outbreaks. The authenticity of war stories is often questioned.Operator literature has become increasingly embellished.Psychopathy can manifest in extreme behaviors.Childhood trauma plays a significant role in shaping future actions.Andre Chikatilo's life reflects a complex interplay of factors leading to his crimes.Narcissism can drive individuals to commit heinous acts.Profiling can be a crucial tool in identifying serial killers.Confessions can be elicited through psychological manipulation.The case of Dean Corll highlights the horrors of predation.Accomplices can be groomed and manipulated into participating in crimes.Understanding the nature vs. nurture debate is essential in criminal psychology.Aileen Wuornos's case reveals complexities in female serial killers. Hosted on Acast. See acast.com/privacy for more information.

UN COUP DE MAIN  AUX HAÏTIENS  YON  KOUTMEN POU  AYISYEN

The focus of this podcast is the enigmatic theme of prion disorders. I trace the history of our understanding of this neurodegenerative disorder with how Nobel laureate D. Carleton Gajdusek, described the transmission of kuru - the first pathologically defined human prion disease. I also narrate how the similarities in the clinical and pathological features of kuru and scrapie, the disease of sheep, opened the way to this breakthrough. I also chronicled how the efforts of another Nobel laureate, Stanley Prusiner, characterised the pathology, genetics and transmission of scrapie, and how he succeeded in a bitter scientific race that transformed the field of transmissible spongiform encephalopathies which he named prion diseases. I also explored the pathology of prions, their normal functions, and how they cause disease when they become misfolded. In this theme, I discussed Creutzfeldt Jakob disease extensively, with reference to the roles played by Alfons Jakob and Hans Gerherdt Creutzfeldt, and depicting its classical manifestations and investigations. I illustrated the lived experience of CJD with such memoirs as Howie V CJD, by Sandy Bosman. I also exhaustively covered the clinical and management aspects of new variant CJD, and I illustrated this with the memoir Who Killed My Son, by Christine Lord. The podcast also reviewed the other established human prion diseases such as fatal familial insomnia, and it explored the similarities between prion diseases and other neurodegenerative diseases that are also related to misfolded proteins, such as Alzheimer's, Parkinson's, and motor neurone diseases. I also covered mad cow and other prion disorders of animals. I cited other helpful books such as Collectors of Lost Souls by Warwick Anderson, Fatal Flaws by Jay Ingram, Madness and Memory by Stanley Prusiner, and Consciousness: A User's Guide by Adam Zeman.

In this week's podcast, Neurology Today's editor-in-chief highlights articles on a study highlighting three-year outcomes for patients with anti-NMDAR encephalitis, an analysis comparing the diagnostic efficacy of skin biopsies vs. CSF tests for human prion diseases, and the ways in which a graduate degree in public health and/or business administration can shape career pathways for neurologists.  

One of the most mysterious and frightening entities in medicine are prion diseases — rare neurodegenerative disorders that are usually infectious in nature but involve not bacteria or viruses, but proteins. Prions are misfolded proteins that can induce normal proteins to become misfolded as well, resulting in a chain reaction that leads to irreversible brain damage and death. What makes prions alarming is that they are incurable, can incubate for decades in a person's brain without symptoms, and are usually associated with 100% mortality within months to a few years. Sonia Vallabh, PhD was a recently-married lawyer in her early career when she witnessed her mother's baffling sudden health decline and death. Her mother was ferried from hospital to hospital, yet dozens of doctors could not figure out why she was seemingly succumbing to rapidly progressive dementia at the age of 52. It wasn't until after her death that Vallabh discovered the cause was a genetic prion disease. Subsequent testing revealed that Sonia Vallabh herself had inherited the same genetic abnormality. Determined to find a solution, Vallabh and her husband Eric, a transportation engineer, decided to retrain as biomedical scientists in a race to cure her before it grew too late. The couple now leads a prion research lab at the Broad Institute at MIT and Harvard. They are also the co-founders of the nonprofit Prion Alliance. Over the course of our conversation, Vallabh opens up about what it was like to accompany her mother in her last months of life, the psychological toll of dealing with a fatal medical mystery, how she lives each day with an awareness of how ephemeral life is, what prion diseases are and what makes them so difficult to treat, what makes her optimistic about the future of her work, and more. In this episode, you'll hear about: 3:23 - Vallabh's early memories of her mother and the devastating experience that overcame her at 52 years old16:37 - The process of grieving the loss a parent22:32 - What prion diseases are25:35 - How Vallabh made the decision to undergo the genetic testing that confirmed she inherited a mutation thah causes prion disease 36:27 - Vallabh's major career change to become biomedical researchers 45:50 - Where the quest for an effective therapy for prion disease currently stands 52:08 - Vallabh's message to listeners on how to approach life View Sonia Vallabh's TED Talk on her quest to cure prion disease. Visit our website www.TheDoctorsArt.com where you can find transcripts of all episodes.If you enjoyed this episode, please subscribe, rate, and review our show, available for free on Spotify, Apple Podcasts, or wherever you get your podcasts. If you know of a doctor, patient, or anyone working in health care who would love to explore meaning in medicine with us on the show, feel free to leave a suggestion in the comments or send an email to info@thedoctorsart.com.Copyright The Doctor's Art Podcast 2024

Prion diseases are caused in people when an aberrant form of a protein that is already in our bodies infects us, and causes the normal protein to fold like it, resulting in neurological disease. A new study found that one … What is a prion and how does it cause disease? Elizabeth Tracey reports Read More »

Prions are misfolded proteins that can infect us and cause our normal proteins to fold incorrectly also, and they can be found in the skin, a new study reports. Ted Dawson, a Parkinson disease expert at Johns Hopkins, says this … A new way of diagnosing prion disease may also help in other diseases, Elizabeth Tracey reports Read More »

Send us a textIn this episode we go into a disease that was limited to one remote area of the world.  A slow death that causes random outbursts of laughter.  How did this happen?  What did the people do to try and stop it?  And what are the rituals surrounding it?  We talk about all this and more!  Enjoy!Support the show

From Bovine Spongiform Encephalopathy (BSE) to Creutzfeldt-Jakob disease (CJD), Neil Mabbott, Ph.D., has worked for nearly 2 decades on understanding the mechanisms by which prion proteins become infectious and cause neurological disease in humans and animals. He discusses the remarkable properties of prions and addresses complexities surrounding symptoms, transmission and diagnosis of prion disease.

Biomedical researcher Sonia Vallabh's life was turned upside down when she learned she had the genetic mutation for a rare and fatal illness, prion disease, that could strike at any time. Thirteen years later, her search for a cure has led to new insights about how to catch and prevent disease — and how to honor our grandest, most mysterious inheritance: our brains.

TWiV discusses secret anti-vax campaign run by Pentagon to undermine China during pandemic, NY governor's subways mask ban proposal, Colorado bat facility sparks outbreak fears, House budget billls suggest ban on gain of function research, evolution of STAT2 resistance to flavivirus NS5, and brainwide silencing of prion protein by AAV-mediated delivery of an epigenetic editor. Hosts: Vincent Racaniello, Dickson Despommier, and Alan Dove Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Pentagan anti-vac campaign to undermine China (Reuters) NY governor subway mask ban (AP News) Colorado bat facility sparks outbreak fears (Science) House NIH budget bans gain of function research (Science) Evolution of STAT2 resistance to flavivirus NS5 (Nat Commun) Brainwide silencing of prion protein by AAV delivered epigenetic editor (Science) Letters read on TWiV 1127 Timestamps by Jolene. Thanks! Weekly Picks Dickson – Mars Odyssey Orbiter is about to make its 100,000th orbit Alan – Local animal shelters and “kitten season.” Vincent – Supreme Court allows cities to ban homeless people sleeping outside, even when shelter space is lacking Listener Picks Blog design – Trump vows to defund schools requiring vaccines for students Jon – Detections of highly pathogenic avian influenza in mammals Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

Biomedical researcher Sonia Vallabh's life was turned upside down when she learned she had the genetic mutation for a rare and fatal illness, prion disease, that could strike at any time. Thirteen years later, her search for a cure has led to new insights about how to catch and prevent disease — and how to honor our grandest, most mysterious inheritance: our brains.

Biomedical researcher Sonia Vallabh's life was turned upside down when she learned she had the genetic mutation for a rare and fatal illness, prion disease, that could strike at any time. Thirteen years later, her search for a cure has led to new insights about how to catch and prevent disease — and how to honor our grandest, most mysterious inheritance: our brains.

Biomedical researcher Sonia Vallabh's life was turned upside down when she learned she had the genetic mutation for a rare and fatal illness, prion disease, that could strike at any time. Thirteen years later, her search for a cure has led to new insights about how to catch and prevent disease — and how to honor our grandest, most mysterious inheritance: our brains.

FOR PRION OUT LOUD PART 1APRIL, 7TH 2024      AARON SMITH      SEASON 1      EPISODE 67 SHOW NOTES: (AI generated)Have you ever wondered just how deep the rabbit hole goes when it comes to the science and satire surrounding public health policies? I'm Aaron Smith, and this episode pulls back the curtain on the controversial topic of mRNA COVID vaccines, with a sprinkle of humor to start us off. We kick things off with a spoof recording that might make you chuckle, but then we get down to the nitty-gritty. Why have I chosen to steer clear of the jab? It's not a decision I've made lightly, and I'm here to share the peer-reviewed research that's had me thinking twice. Together with special contributor Brock Tanslacks, we're stirring up a crucial conversation about vigilance and personal choice in the face of experimental medical treatments.Strap in for a chapter that shifts gears from playful banter to the pressing issue of potential health risks that accompany uncharted scientific territory. Adopting the mindset of 'guilty until proven innocent,' we examine the principle of doing no harm in the face of emergency medical interventions. And as we ponder the hypothesis correlating the spike protein in COVID vaccines with prion diseases, it's clear that this is no laughing matter. The stakes are high, and the need for greater scrutiny is evident. By the end of this episode, you'll have a whole new perspective on the delicate balance of information and the implications our health choices today could have for years to come.LINKS:NIH- A Potential Role of the Spike Protein in Neurodegenerative Diseases: A Narrative Reviewhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922164Wikipedia UK Mad Cow Disease:https://en.wikipedia.org/wiki/United_Kingdom_BSE_outbreak#ReferencesDeadly Feasts:https://www.simonandschuster.com/books/Deadly-Feasts/Richard-Rhodes/9780684844251Brain Trust:https://www.simonandschuster.com/books/Brain-Trust/Colm-A-Kelleher/9781416507567Pinky and the Brain:https://www.youtube.com/watch?v=e_mPrhwpZ-8THE SUBTLECAIN SPOTLIGHT: MOE FACTZ WITH ADAM CURRYhttps://www.moefactz.comSupport the showYou are valued, you are loved, and you are worthy.

Get your DEMYSTICON 2024 tickets here: https://www.eventbrite.com/e/demysticon-2024-tickets-727054969987 Today we are hanging out with our friend Dr. Michael Hughes, a post-doctoral fellow at St. Jude's Research Hospital in Memphis. Michael has a long history of trying to understand the role that water plays in fundamental biological operations from structural assembly to diseases like Alzheimers and Prion disorders. Presently, he is hard at work on a biological theory of everything where water plays out the role of central actor in biological processes from form to consciousness. Our conversation today begins with Michael's journey into the water rabbit hole, exploring the strange way that water structures itself within cells. We work toward an understanding of water as a photo-electrically, an electro-statically sensitive molecule capable of mechanically altering cellular function in response to conscious and external signals. We hope to have Michael back to explore a mutual fascination with the historic interface of spirituality and science by way of Rudolph Steiner and Western esotericism. Tell us your thoughts in the comments!!! Sign up for a yearly Patreon membership for discounted conference tickets: https://bit.ly/3lcAasB Gilbert Ling's website & books: https://www.gilbertling.org/books.html Modern review based on the Association Induction Hypothesis: https://pubmed.ncbi.nlm.nih.gov/32565181/ Rice University Archives of the Impossible: https://libguides.rice.edu/impossiblearchives (00:00) Go! (00:09:25) APS 2024 (00:11:01) Biochemistry to Cell Biology to Water Physics (00:12:49) Math has true answers (00:16:21) Prions, amyloids (00:25:49) Stress granules as proto-organelle (00:32:38) Aging as disease or no? (00:44:08) Water as biological theory of everything (00:57:19) Transient h-bonding structures (01:15:11) Water density as biological master switch? (01:26:41) Water as dark matter of consciousness (01:40:13) UAPs to be taken seriously? (01:54:36) Evidence-based beliefs? (02:11:43) Remote viewing (02:28:10) Science without spirituality? #science #sciencepodcast #BiologicalResearch #WaterInScience #ConsciousnessStudies #CellularFunction #MedicalScience #StJudesResearch #Biochemistry #AlzheimersResearch #PrionDisorders #ScienceAndSpirituality #PodcastInterview #MedicalInnovation #ResearchInsights #ScienceCommunication #HealthAndWellness #WaterMolecule #StructuralBiology #ConsciousnessExploration #SpiritualScience #SciencePodcast #structuredwater #waterscience #waterchemistry Check our short-films channel, @DemystifySci: https://www.youtube.com/c/DemystifyingScience AND our material science investigations of atomics, @MaterialAtomics https://www.youtube.com/@MaterialAtomics Join our mailing list https://bit.ly/3v3kz2S PODCAST INFO: Anastasia completed her PhD studying bioelectricity at Columbia University. When not talking to brilliant people or making movies, she spends her time painting, reading, and guiding backcountry excursions. Shilo also did his PhD at Columbia studying the elastic properties of molecular water. When he's not in the film studio, he's exploring sound in music. They are both freelance professors at various universities. - Blog: http://DemystifySci.com/blog - RSS: https://anchor.fm/s/2be66934/podcast/rss - Donate: https://bit.ly/3wkPqaD - Swag: https://bit.ly/2PXdC2y SOCIAL: - Discord: https://discord.gg/MJzKT8CQub - Facebook: https://www.facebook.com/groups/DemystifySci - Instagram: https://www.instagram.com/DemystifySci/ - Twitter: https://twitter.com/DemystifySci MUSIC: -Shilo Delay: https://g.co/kgs/oty671

New clinical trials for treatments of an always fatal brain disease, and what happens with pests when a conventional and organic farm are neighbors   First up on this week's show, a new treatment to stave off prion disease goes into clinical trials. Prions are misfolded proteins that clump together and chew holes in the brain. The misfolding can be switched on in a number of ways—including infection with a misfolded prion protein from an animal or person. Staff Writer Meredith Wadman talks with host Sarah Crespi about new potential treatments—from antisense nucleotides to small molecules that interfere with protein production—for these fatal neurodegenerative diseases.   Next on the show: Freelance producer Katherine Irving talks with Ashley Larsen, associate professor of agricultural and landscape ecology at the University of California, Santa Barbara, about the effects of organic farms on their neighbors. If there are lots of organic growers together, pesticide use goes down but conventional farms tend to use more pesticides when side by side with organic farms.   This week's episode was produced with help from Podigy.   About the Science Podcast   Authors: Sarah Crespi; Katherine Irving; Meredith Wadman LINKS FOR MP3 META   Episode page: https://www.science.org/doi/10.1126/science.z91m76v

TWiV reviews resurgence of Lassa fever in West Africa, at least 3 paralytic cases of cVDPV2 in Zimbabwe, CWD from eating prion-laden plants, measles in New Orleans and Broward County Florida, failure of Florida Surgeon General to support vaccination, a measles variant in Switzerland, SARS-CoV-2 persistent infections, leaky blood-brain-barrier for long COVID brain fog, West Nile virus transmitted among mosquitoes by the excreta, and viroid-like colonists of human microbiomes. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit and Kathy Spindler Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommier Viruses of Microbes 2024 Resurgence of Lassa fever (Science) cVDPV2 in Zimbabwe (UNICEF) CWD from eating plants (CIDRAP) Measles in New Orleans (LA Dept Health) SARS-CoV-2 persistent infections (Nature) Leaky BBB for brain fog of long COVID (Nat Neurosci) Measles in Broward County FL (7 News) Failure of FL Surgeon General to support vaccination (X) Measles variant (Eurosurveillance) West Nile virus transmitted among mosquitos by excreta (bioRxiv) Mosquito life cycle (YouTube) Viroid-like colonists of human microbiomes (bioRxiv) Letters read on TWiV 1091 Timestamps by Jolene. Thanks! Weekly Picks Dickson – Sustainable energy in America 2024 factbook Kathy – Life Magnified USPS stamps Rich – “How plants communicate with each other when in danger” by Kasha Patel (Original Nature Communications article) Alan – A Sargasso Sea of Space card game. Vincent – Tell Me When It's Over by Paul Offit Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

The Crazy Town Podcast "Prion Chat"

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: July 18, 2017 Prions are perhaps some of the most terrifying infectious particles known to man. But did you know that patients with some prion diseases actually shed these contagious proteins in their urine? These and other facts about prion diseases are discussed in this week's episode of BrainWaves. BrainWaves podcasts and online content are intended for medical education only and should not be used to guide medical decision-making in routine clinical practice. REFERENCES Zabel MD, Reid C. A brief history of prions. Pathog Dis 2015;73(9):ftv087. PMID 26449713Rutala WA, Weber DJ. Creutzfeldt-Jakob disease: recommendations for disinfection and sterilization. Clin Infect Dis 2001;32(9):1348-56. PMID 11303271Glatzel M, Abela E, Maissen M, Aguzzi A. Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease. N Engl J Med 2003;349(19):1812-20. PMID 14602879Moda F, Gambetti P, Notari S, et al. Prions in the urine of patients with variant Creutzfeldt-Jakob disease. N Engl J Med 2014;371(6):530-9. PMID 25099577Wieser HG, Schindler K, Zumsteg D. EEG in Creutzfeldt-Jakob disease. Clin Neurophysiol 2006;117(5):935-51. PMID 16442343Lapergue B, Demeret S, Denys V, et al. Sporadic Creutzfeldt-Jakob disease mimicking nonconvulsive status epilepticus. Neurology 2010;74(24):1995-9. PMID 20445151Siegler JE, Jacobs DA, Amado D, Adams JL, Berger JR. Rapidly progressive dementia with hypoglycorrhachia. J Clin Neurosci 2015;22(10):1685-7. PMID 26094562Geschwind MD. Prion diseases. Continuum (Minneap Minn) 2015;21:1612-38. PMID 26633779  We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

Mad cow disease, also known as bovine spongiform encephalopathy (BSE) was first discovered in cattle in the UK in 1986. In 1996, BSE made its way into humans for the first time, setting off panic and fascination with the fatal disease that causes rapid onset dementia. In this episode, Sam and Deboki cover the cause, spread and concern surrounding mad cow and other prion diseases. The Tiny Show & Tell stories are here and here.

On episode #29 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/11 – 5/23/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Harmonie phase IIIb study trial results of nirsevimab against RSV lower respiratory tract infection hospitalization for infants (ESPID) Mogamulizumab for treatment of HTLV-1 associated Myelopathy/Tropical Spastic Paraparesis (IDSA) Revised protocol for secondary prevention of congenital cytomegalovirus infection with valaciclovir (IDSA) Increase in false positive fourth generation HIV tests in patients with COVID-19 (CID) Implementation of an antibiotic stewardship initiative in a large urgent care network (JAMA) Clindamycin + vancomycin versus linezolid for treatment of necrotizing soft tissue infection (OFID) Assessing empiric antimicrobial therapy with the dundee classification for skin and soft tissue infections (OFID) Combination of amoxicillin 3000mg and probenecid vs 1500mg amoxicillin monotherapy for treating syphilis in patients with HIV (CID) The sympathetic nervous system is necessary for development of CD4+ T cell memory following Staphylococcus aureus infection (JID) Efficacy and safety of sulbactam-durlobactam versus colistin for the treatment of patients with infections caused by Acinetobacter baumannii-calcoaceticu complex (The Lancet) First reported US cases of tinea caused by Trichophyton indotineae (CDC) How to use direct microscopy for diagnosing fungal infections (CMI) Limited Cutaneous Leishmaniasis as Ulcerated Verrucous Plaque on leg (EID) Can Ivermectin kill Sarcoptes scabiei during the molting process? (PLOS) The Infectious Diseases Specialist, at risk of extinction (JID) Ticks harbor and excrete chronic wasting disease prions (NIH) Music is by Ronald Jenkees

Count how many times we have to remind ourselves of the pronounciation of this one. Prion diseases are terrifying, that's the summary. Now go play Plague, Inc. Sources: CDC Website Friendly Neighborhood Immunologist discusses prion diseases Check out our Patreon! Support us for $1/month for a shoutout, or $3/month for access to unedited video of each podcast episode and monthly additional content. Follow us on Instagram and Twitter @biopsychpod, and find us on Facebook too! Music by JayMan at https://bit.ly/2uWO2jO

On episode #21 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 1/18/23 – 2/1/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode The impact of cold temperature in the pattern of influenza virus infection (OFID) Janssen to discontinue Phase 3 Mosaico HIV vaccine clinical trial (JNJ) Randomized trial of vaccines for Zaire Ebola virus disease (NEJM) PD-1 blockade and lenalidomide combination therapy for Epstein-Barr virus infection (CMI) Outcomes of Daptomycin plus Ceftaroline vs alternative therapy for persistent MRSA bacteremia (IJAA) Detection of a novel strain of multidrug-non-susceptible Neisseria gonorrhoeae (The Lancet) Impact of a device to reduce blood culture contamination and false-positive central-line bloodstream infections (ICHE) Addition of anaerobic coverage for treatment of biliary tract infections (JAC) High dose Cefepime vs Carbapenems for bacteremia caused by Enterobacterales(OFID) Assessing the diagnostic performance of IGRAs for Mycobacterium tuberculosis (CID) Infective endocarditis after transcatheter aortic valve replacement (JACC) Discordant clinical and microbiological outcomes are associated with late clinical relapse in clinical trials for complicated UTIs (CID) Real-world use of bezlotoxumab and fecal microbiota transplantation for the treatment of Cdiff (OFID) Blastomycosis in New England (OFID) Management of invasive candidiasis in hematopoietic cell transplant recipients (TCT) Short course of Antifungal therapy in patients with uncomplicated Candida Bloodstream infection (OFID) Parasites and childhood stunting (Cell) Comparing complication rates of midline catheter vs. PICC line (OFID) Novel prion strain as the cause of chronic wasting disease in a moose (EID) Agreement of respiratory viruses' detection between nasopharyngeal swab and bronchoalveolar lavage in adults with pneumonia (CMI) Music is by Ronald Jenkees

011823 Susan On New Prion Disease From Shots Commitee On Weaponization Readers On Why No SHots by Kate Dalley

Today on the Opinions That Don't Matter podcast we find Kati and Sean talking about Time Travel, Jello Mold recipes that are awful and being scared of the basement. Come for the laughs, stay for the science talk. Australians follow the rules ttps://www.instagram.com/reel/ClVIoldhd8y/?igshid=YmMyMTA2M2Y%3D Jaywalking - Two types of people in life… Identification, CLEAR, Real ID, TSA PreCheck, NEWS Trump Organization found guilty of tax fraud scheme https://tinyurl.com/2wvuu92x A new writer tweeted about a low book signing turnout, and famous authors commiserated https://tinyurl.com/ynnx7amr Kati has injured her back. Was it yoga? Is it the Piriformis Syndrome. Sean is not a Dr. What is Acupuncture. New needles are better than the old needles. Gift opening… Thank you Christy & Joolz! Love them. LETTERS Would you go back in time to...... - Erin the awesome Toronto Contributor TV Shows: Quantum Leap and Early Edition. Was it Jesus who delivered the paper? Being scared by films, Lost Highway has a very creepy scene. Hallways and staircases are scary too. How Fast Can You Run If You Are Scared? The 30 Stair Dash from the basement. Something to do to chapter 133 and Kati's new book

Episode 1898 - Celine diagnosed with a neurological disorder? Ted discusses The Book of Eli. Insane merchant of death prisoner exchange with Russia. Jordan Peterson really messed up in an interview. IRS to tax eBay sales. Musk takes aim at Wikipedia. Nigeria restricts withdrawals to 45 a day to implement digital currency. What is Prion disease? High energy must listen show!

Prion disorders are rare neurological diseases where a protein within the nervous system converts to a pathological form. The change in conformation affects other proteins, recruiting them to the misshapen, deleterious type. Chronic wasting disease is a neurological disease of deer, caused by prion conversion. In this episode Dr. Sandra Pritzkow from University of Texas Health - Houston describes prion related disease, and specifically the atypical transmission elements of chronic wasting disease. 

In 18th-century England, inbred sheep are afflicted with a disease that leaves them with an unscratchable itch. In New Guinea, a group of indigenous people blame sorcery for “kuru,” a disease causing tremors and uncontrollable fits of emotion. By the 1980s, scientists discovered they shared a groundbreaking link — one that could help explain why an Italian family was dying of insomnia.  Parcasters, we have exciting news! Our first book hits bookshelves July 12th. Don't miss this chilling summer read that takes you deep into the darkest sides of human nature. Learn more and grab your copy at www.parcast.com/cults! Learn more about your ad choices. Visit podcastchoices.com/adchoices

Generations of a Venetian family succumbed to a mysterious illness that stopped them from entering a state of deep rest. Without sleep, they died. Faced with an early and terrible death, members of the family grew determined to unlock the secrets of their wicked inheritance.  Parcasters, we have exciting news! Our first book hits bookshelves July 12th. Don't miss this chilling summer read that takes you deep into the darkest sides of human nature. Learn more and grab your copy at www.parcast.com/cults! Learn more about your ad choices. Visit podcastchoices.com/adchoices

TWiV revisits chronic wasting disease of cervids and the ability of the prions to infect meadow voles and raccoons, and the suggestion that stochastic assembly of influenza virus particles may play a role in phenotypic diversity. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Amy Rosenfeld Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode CWD in meadow voles and raccoons (Emerg Inf Dis) Unusual infectious agents (Virology Live) Low fidelity influenza virus assembly (Cell) Shape-shifting viruses (TWiV 743) From variolous effluvia to VLPs (TWiV 170) A pox on your horse (TWiV 478) Letters read on TWiV 878 Timestamps by Jolene. Thanks! Weekly Picks Dickson – James Webb Space Telescope and Nature Conservancy Photo Contest Amy – A new strategy for staying one step ahead of the virus Rich – Searching for the origin of the smallpox vaccine: Edward Jenner and his little-known horsepox hypothesis Vincent – Blacktail Studio Listener Picks Richard – Water Structure and Science Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv