POPULARITY
In this podcast, we spoke with Ryan Bernhardt, CEO of Biosero and Jesse Mulcahy, Director and Head of Automation at Cellino about the importance of utilizing automation in cell therapy research and production and the potential of these technologies to transform the healthcare landscape and improve patient access. The Challenge of Accessibility in Cellular Therapy The traditional methods of creating induced pluripotent stem cells (iPSCs) are notoriously laborious and expensive, often costing hundreds of thousands, if not millions, of dollars per patient. This high cost poses a substantial barrier to accessibility for many patients in need of personalized cell therapy treatments. Cellino is leveraging advanced automation, AI, and linear technology to dramatically redefine and improve on traditional production processes. Advancing Automation in Cell Therapy Cellino's approach employs its innovative technology, known as NEBULA. This system utilizes self-contained units, referred to as cassettes, to cultivate personalized cell therapies directly in hospitals. NEBULA uses AI to monitor cell growth while incorporating laser technology to selectively eliminate unhealthy cells. This level of automation has the potential to reduce the manufacturing costs of personalized stem cell therapies by at least tenfold, making treatments more accessible to a broader range of patients. Supporting automation for Cellino is Biosero's Green Button Go software suite, which plays a crucial role in automating the workflows of life science organizations. Ryan explained how their technology empowers life science organizations to automate essential scientific processes, facilitating the scheduling of workflows and direct communication with lab instruments. With the capability to run processes continuously—day or night—labs can maintain and cultivate cells without the constraints of a conventional workweek. This 24/7 operational capacity allows for the rigorous demands of cellular therapeutics to be met more efficiently. Bridging Gaps with Integrated Automation Ryan describes how lab automation can no longer be seen as merely robotic arms and conveyor belts; it integrates three key elements: physical, logical, and data. By orchestrating these components, automation streamlines and accelerates research across labs that were traditionally siloed and specialized in specific areas. This approach connects different labs, unifying knowledge, expertise, and data systems, enabling real-time decision-making and data-driven insights. Automation enhances workflows by eliminating delays and optimizing project timelines. It serves as a performance tool for scientists, improving efficiency, consistency, and the ability to address complex challenges, while also incorporating AI and machine learning for smarter, continuous processes. Jesse Mulcahy, Director and Head of Automation at Cellino emphasized the significance of Biosero's orchestration software in improving efficiency by optimizing scheduling, reducing downtime, and maximizing throughput in cell therapy production. The Green Button Go orchestrator improves consistency by automating key steps and minimizing human intervention, ensuring reproducible results for quality control. The software is flexible and modular, allowing for easy adaptation of workflows as needs evolve, whether adding new instruments or changing protocols. This scalability is crucial for producing personalized cell therapies more efficiently and at a larger scale. Addressing Pain Points and Future Trends Despite the advancements, there are still hurdles to overcome in the biologics' development landscape. Ryan notes that the field is evolving rapidly, with significant advancements in cell culturing, automation, and decision-making processes. Traditional cell culturing is being automated to assess key factors like cell viability, confluence, and other qualitative aspects, aiding decisions on feeding, splitting, and harvesting.
Cell therapy research and manufacturing are driving demand for automated high-throughput equipment to improve quality, reduce costs, and shorten the development cycles of innovative treatments that save lives. But what factors shape a startup's journey from the lab to commercialization?In Episode #35 of the Speed to Data podcast, Key Tech Business Development Manager Kelly Parker leads a panel of industry experts who discuss high-throughput automation in cell therapy screening and manufacturing.Daniela Hristova-Neeley, Ph.D., is a partner at the advisory firm Health Advances, where she is a leader in the diagnostics and life sciences tools practice.Blair Morad is Senior Director of Engineering at Cellino, a startup developing autonomous biomanufacturing technology for personalized cell therapies.Nova Syed is a founder and angel investor in the deep tech and healthcare sector. Most recently, Syed was the founding VP of Product at Mekonos, a developer of silicon nano-needles for cell therapies.Need to knowThree factors drive requirements in cell therapy screening:· Customers are studying a huge variety of biological systems and drug targets. · Business requirements drive the need for faster and cheaper therapy development.· Meeting regulatory standards demands high-quality, reproducible data.In manufacturing, meeting GMP makes design requirements even more complex as the product must:· Improve flexibility and scalability.· Improve quality control and traceability.· Lower manufacturing costs.· Reduce human interaction to improve efficiency and quality.The nitty-grittyGiven the many competing business, market, and regulatory requirements, the instrument design process inevitably forces developers to make tradeoffs.The panelists agreed that quality is table stakes, which means technologists and business leaders must balance time, cost, and scope.“You have to be ruthless when it comes to prioritizing your differentiator,” Hristova-Neeley said.In Morad's experience, understanding the organization's core competency is essential to focusing on the right problems.Data that made the differenceThe three panelists shared their lessons learned from hard experience in the healthcare technology business.Get early feedback from the market. “Product-market fit doesn't just happen,” Syed explains. “Unless you get feedback directly from the users and the customers, you don't have the data to iterate to the next cycle.”Hristova-Neeley agreed. “It's always important to hear what the customers have to say. Automation is certainly important, but it's not the only thing that is going to solve how we do cell therapy manufacturing or cell therapy development.”Look for outside expertise. “When you're working with the right experts,” Morad said, “they know how to ask the right questions that are helpful to move forward.” A good startup employs many intelligent people, but they won't know everything about everything. Find outside partners who have already built the assays, workflows, automation modules, and other elements outside your core competency so you can focus on your innovations.
On today’s episode, Matt Tamanini is in conversation with the stars of one of the funniest shows running in New York City, “Cellino v. Barnes,” Eric William Morris and Noah Weisberg. The pair discuss the in-depth, method approach that they took to portraying these real-life figures, what it’s like having read more The post Special Episode: Morris and Weisberg on ‘Cellino v. Barnes’ appeared first on BroadwayRadio.
Comedian Mike Vecchione joins Shannon And Figs. They discuss why Figs was late and why he chose to wear a blazer over a tanktop, the comedic play about injury attorneys Cellino & Barnes, a recap of The Bachelorette season finale and more. Then they dive into the stories including Mike's friend who turned dating into an algorithm, his sunset engagement story, getting into a group fight as a teenager, a look at some of the most convincing supernatural videos on the internet plus so much more!Air Date: 9/10/24Support our sponsorsYoKratom.com - Click The Link To Get A $60 Kilo TodayYoDelta.com - Use promo code GAS for 25% off your order!**Send in your stories for Bad Dates, Bad Things, and Scary Things to...**thethingispodcast@gmail.comThe Thing Is... Airs every Tuesday, at 4PM ET on GaS Digital! The newest 20 episodes are always free, but if you want access to all the archives, watch live, chat live, access to the forums, and get the show days before it comes out everywhere else - you can subscribe now at gasdigital.com and use the code TTI to get 20% off your membership!Mike VecchioneInstagram: https://www.instagram.com/comicmikevShannon Lee-Instagram: @shannonlee6982Mike Figs-Instagram & YouTube: @comicmikefigsSubscribe On YouTube: https://www.youtube.com/channel/UC87Akt2Sq_-YEd_YrNpbS2QSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
This episode we are joined by actor, writer, director and producer Noah Weisberg! Noah is currently starring in Cellino v Barnes at The Asylum NYC! His credits included the national tour of Charlie and the Chocolate Factory as Willy Wonka, on Broadway in Legally Blonde, Enron and South Pacific. You've seen him on TV in Zoey's Extraordinary Playlist, Super Pumped, Law & Order, Modern Family and so many other shows…! He also has a production company called Shermerville and you can check out his short films Thank You Kindly and What's Life Got to Do with It!
New York City Comptroller Brad Lander says money the city spends on lawsuit settlements should come from the budgets of the accused agencies. This comes after a WNYC investigation revealed a former Rikers Island officer is facing 24 sexual assault allegations. Meanwhile, a play based on injury attorneys Cellino and Barnes is back off Broadway. WNYC's Ryan Kailath reports. Also, a block in Crown Heights has won Brooklyn's “greenest block” contest organized by the Brooklyn Botanic Garden. Plus, for the first time, talking drones warned New Yorkers in flood-prone areas about severe weather on Tuesday. These drones are typically used by police to disperse crowds. Finally, while heavy rain has mostly stopped, officials reported overnight flash flooding in New York City and the surrounding area. WNYC's David Furst speaks with New York State Homeland Security and Emergency Services Commissioner Jackie Bray about the city's response.
Rubrik's strong IPO pricing and warm reception by the public markets after its listing add more weight to the perspective that the public markets are not as closed to tech startups as some thought. If Rubrik's result isn't enough to break the logjam, well, maybe there's something else going on.But there was a lot more that happened this week, which meant that the Equity crew had a pile of news to get through as always, with a little bit of our own mixed in. Happily it was all pretty darn interesting, so Mary Ann and Alex started with Rubrik before pivoting to Pomelo, a startup that has a very interesting twist on the remittances market.From there it was time to talk about TikTok. What was once an unfathomable result — TikTok being forced to divest from its parent company or face a ban — became reality pretty darn quickly. The United States is not the first company to ban the service, but we noted during the show that the company we are keeping is not the most enticing. Still, here we are, what does it mean for consumers?And to close, Early Stage. TechCrunch held its annual early-stage focused even this year, and it was a banger. Not to toot our own horn, but it was the second year in a row that our shindig in Boston was packed, useful, and lots of fun. The coffee was even good. At a tech conference. Alex had notes.Equity is back on Monday. Thanks for hanging out with us!Equity is TechCrunch's flagship podcast and posts every Monday, Wednesday and Friday, and you can subscribe to us on Apple Podcasts, Overcast, Spotify and all the casts.You also can follow Equity on X and Threads, at @EquityPod.For the full interview transcript, for those who prefer reading over listening, read on, or check out our full archive of episodes over at Simplecast. Credits: Equity is hosted by TechCrunch's Alex Wilhelm and Mary Ann Azevedo. We are produced by Theresa Loconsolo with editing by Kell. Bryce Durbin is our Illustrator. We'd also like to thank the audience development team and Henry Pickavet, who manages TechCrunch audio products.
Smarty hosts Jay and Luke in this week's main pod Hosted on Acast. See acast.com/privacy for more information.
BlueCollar.CEO –Lucas Cellino is the President and CEO of Cellino Plumbing, a family-owned and operated plumbing and HVAC company servicing Buffalo, NY since 1995. Lucas started in the business at 12 years old, helping his dad on jobs between hockey practices. In 2002, he was hired on as a soil relocation engineer and by 2016 he was serving as the company's President and CEO. Lucas is also the Managing Partner of Cellino and Wangelin Construction. In this episode, Ryan and Lucas discuss how community involvement can impact your company's culture and your bottom line.Blue Collar CEO is a podcast that is all about helping you build a better, more profitable, more sustainable & kick-ass home service business. Join Levergy® CEO Ryan Redding each week who will be joined by industry experts who will break down their success stories and give their best-kept secrets for industry domination. You do not want to miss it! Learn more at https://www.bluecollar.ceo/, or https://www.levergy.io.
Gnonto, Phillips, McKennie, Llorente, Kristensen, Cellino, Berardi, Radz and more!
We're delighted to be joined by a former-player who has made who has made over 450 Football League appearances with the likes of Bolton, Portsmouth, Leeds United, Ipswich Town and of course Plymouth Argyle - while playing under the likes Steve Evans, Roy Keane, Sam Allardyce, Neil Warnock, Tony Pulis, Ian Holloway and Sir Paul Sturrock. It is of course; the 2003-04 Title Winning, David NorrisIn an incredibly open and honest interview David opens up predominantly about his time with Argyle, touching on Sturrock's reign, lifting the league title, THAT goal up at Bournemouth, the celebrations after QPR, Nearly following Pulis to Stoke, Ian Holloway's strange team talks, Scott Sinclair or Ákos Buzsáky, playing Watford in the FA Cup Semi-Final, facing Real Madrid, Holloway vs Stapleton, and followed by the reason why he handed in his transfer request and headed for Ipswich. We also touch on his stints under Warnock, Keane, Evans and Allardyce, THAT Celebration, fading out at Portman Road, the move to Pompey, playing for a club in administration, seeing staff sacked, Warnock up at Leeds, Cellino's ownership, why he's selling off his match-worn memories and life after playing. #pafc | #bwfc #itfc #pompey #lufc Hosted on Acast. See acast.com/privacy for more information.
If Andrea Radrizzani is embroiled in a lengthy and costly legal dispute and it doesn't involve Leeds United, does it make a sound?
It's hard to forget catchy commercial jingles from childhood like the one from Cellino & Barnes. Barnes' untimely death could have been another post on Nikki's saved Reddit/r/lastimages. Nikki went to see the Barbie movie (EXTREME SPOILERS) but would have rather watched something about "complete destruction". Brian is still agonizing over his mattress, revealing more about his decision making process. Nikki lets herself off the hook easily when she destroys or loses her things. In the Final Thought, Nikki reconsiders her friendship with Brian after he tells her a story about driving in fog. --- Watch this episode on our Youtube Channel: The Nikki Glaser Podcast Follow the pod on Instagram for bonus content: @NikkiGlaserPod Leave us your voicemail: Click Here To Record Nikki's Tour Dates: nikkiglaser.com/tour Anya's Patreon: patreon.com/anyamarina Brian's Animations: youtube.com/@BrianFrange More Nikki: IG More Anya: IG More Brian: IG More producer Noa: IGSee omnystudio.com/listener for privacy information.
Dr. Alice Cellino is the Executive Director at the Columbus Speech and Hearing Center, a practice offering diagnostic audiology, speech-language pathology, and occupational therapy services. She has been with the location for more than 15 years, developing specialties in diagnostic audiological and vestibularological services for adults and children alike. Dr. Cellino attended Auburn University to earn her doctorate in audiology, previously majoring in business administration at Columbus State University. In this episode… Speech pathology and audiology are deeply related but often separate fields. They both delve deep into listening, hearing, and the underlying psychology, yet they rarely work in tandem. Some clinics are experimenting with blending and working with both. The Columbus Speech and Hearing Center is a rapidly-growing clinic that combines speech pathology and audiology practices. While they have specialists in both fields, they are able to serve their patients in a unique way. So how does their practice operate? In this episode of the ListenUp! Podcast, Dr. Mark Syms is joined by Dr. Alice Cellino, the Executive Director of the Columbus Speech and Hearing Center, to discuss the overlap between speech pathology and audiology. They talk about how she entered the field, her work as a director, and her practice's work. The two also touch on the future of the clinic and the influence of technology.
The personal injury firm Cellino & Barnes made a name for itself with catchy TV jingles, ubiquitous billboards, bus stop ads and more. The duo acrimoniously parted ways in 2020, and just months later, Stephen Barnes was killed in a plane crash in upstate New York. Their story now appears on stage in the form of a play called "Cellino v. Barnes," written and performed by Mike B. Breen and David Rafailedes, who join us to talk about the production. "Cellino v. Barnes," is running through May 7.
Anheuser-Busch Dylan Mulvaney Statement, Tik Tok Banned, Cellino and Barnes The Play, plus the Pentagon leaks, Nic Cage's favorite movies, Biden's lick gate, the King's concert, and more! #BudLight #TikTokBan #PentagonLeaks Get more AoA and become a member to get access to perks: https://www.youtube.com/channel/UCOfx0OFE-uMTmJXGPpP7elQ/join Subscribe to our Podcast clips channel! - http://bit.ly/AoAClips Get Merch here - https://bit.ly/AnthonyMerch Subscribe to the Anthony On Air Podcast here: Facebook - https://bit.ly/AntOnAirFB YouTube - https://bit.ly/AntOnAirYT Apple Podcast - https://bit.ly/AntOnAirApple Google Podcast - https://bit.ly/AntOnAirGoo Spotify - https://bit.ly/AntOnAirSpot Stitcher - https://bit.ly/AntOnAirSti Overcast - https://bit.ly/AntOnAirOv Twitter - https://bit.ly/AntOnAirTwitter Instagram - https://bit.ly/AntOnAirInsta Get more at https://www.AnthonyOnAir.com --- Send in a voice message: https://podcasters.spotify.com/pod/show/anthonyonair/message
March 31, 2023. Marinna Madrid, PhD, co-founder and chief product officer at Cellino, talks about her groundbreaking work in developing lasers as a doctoral student and her company's innovative approach for manufacturing personalized cell-based therapies including those for retinal diseases.
EXCLUSIVE NordVPN Deal ➼ https://nordvpn.com/secondtier Try it risk-free now with a 30-day money-back guarantee! #ADRyan Dilks chats to former Cardiff, Huddersfield, Leeds and current Rotherham defender Lee Peltier.Warnock's magic at Cardiff!Huddersfield's "ridiculous" League One squad!Cellino's madness at Leeds!His take on the Rotherham v Cardiff waterlogged pitch!It's the Second Tier.Website: www.secondtierpod.co.ukTwitter: twitter.com/secondtierpodYouTube: https://www.youtube.com/channel/UCjqVFKB1yw2z_XyVINhB9qA/featured***Please take the time to give us a review and rating on whatever platform you listen to us on. It massively helps up and goes a long way towards us getting new listeners! Thank you.*** Hosted on Acast. See acast.com/privacy for more information.
EXCLUSIVE NordVPN Deal ➼ https://nordvpn.com/secondtier Try it risk-free now with a 30-day money-back guarantee! #AD Ryan Dilks chats to former Cardiff, Huddersfield, Leeds and current Rotherham defender Lee Peltier. Warnock's magic at Cardiff! Huddersfield's "ridiculous" League One squad! Cellino's madness at Leeds! His take on the Rotherham v Cardiff waterlogged pitch! It's the Second Tier. Website: www.secondtierpod.co.uk Twitter: twitter.com/secondtierpod YouTube: https://www.youtube.com/channel/UCjqVFKB1yw2z_XyVINhB9qA/featured ***Please take the time to give us a review and rating on whatever platform you listen to us on. It massively helps up and goes a long way towards us getting new listeners! Thank you.*** Learn more about your ad choices. Visit megaphone.fm/adchoices
Joey Had a Good Potatoes Weekend! We're back and we're not sponsored anymore. Please tell your friends to listen so that we can become sponsored again. Make yourself a Pomme Anna, it's dank as hell! Also no one take Zoctor Doctor, we claim it. If you're having literary legal problems, call Cellino and Barnes and Noble - 800-888-8888-88888888 Like, subscribe, follow @gabwithbab on Twitter & @gabbingwithbabish on instagram and electronically mail us @ gabbingwithbabish@gmail.com!
Willa Paskin, a former TV critic, is the host of the podcast Decoder Ring. “I want it to feel like a trap door. When you push on a trap door, there's like a little spring. If it's the right idea, you start to look into it, and you're like, Oh, it's giving a little.” Show notes: @willapaskin 00:00 Paskin's Slate archive 00:00 Paskin's Salon archive 00:00 Paskin's Vulture archive 00:00 Decoder Ring (Slate) 00:00 "The Invention of Hydration" (Decoder Ring • Slate • Apr 2021) 00:00 "Cellino & Barnes, Injury Attorneys, 800-888-8888 " (Decoder Ring • Slate • Dec 2022) 01:00 "The Sideways Effect" (Decoder Ring • Slate • May 2022) 03:00 "Why I Became a TV Critic" (Slate • Jan 2016) 38:00 "The Laff Box" (Decoder Ring • Slate • Apr 2018) 38:00 "The Blue Steak Experiment" (Decoder Ring • Slate • Dec 2020) 40:00 "Chuck E. Cheese Pizza War" (Decoder Ring • Slate • Jun 2019) 40:00 "The Cabbage Patch Kids Riots" (Decoder Ring • Slate • Nov 2020) 42:00 "Selling Out" (Decoder Ring • Slate • Aug 2021) 42:00 "The Sign Painter" (Decoder Ring • Slate • Jun 2021) 53:00 "The Butt and the Bustle" (Decoder Ring • Slate • Nov 2022) Learn more about your ad choices. Visit podcastchoices.com/adchoices
Synopsis: Nabiha Saklayen, PhD, is the Co-Founder and CEO of Cellino Biotech, a company working to democratize access to personalized stem cell-based therapies for patients at scale. Nabiha joins host Rahul Chaturvedi for a discussion about her entrepreneurial journey and her learning process in the early days of building a start-up. She talks about opportunities and challenges in the field of regenerative medicine and the exciting science her team is pursuing at Cellino to use stem cell-derived regenerative medicines to treat diseases such as Parkinson's, diabetes, and heart disease. She also touches on changes and trends in biotech she's observed over the years. Nabiha first appeared on the Biotech2050 podcast for its 100th episode - listen here: https://on.soundcloud.com/HkAxq Biography: Nabiha Saklayen is the Co-Founder and CEO of Cellino. Cellino's proprietary technology makes personalized stem cell-derived therapies scalable for the first time. Nabiha was selected as a Pioneer in MIT Tech Review's 35 Innovators under 35 list for her patented inventions in cellular laser editing. She received her Ph.D. in Physics from Harvard University as a Howard Hughes Medical Institute (HHMI) International Fellow. She is also the inaugural Tory Burch Foundation Fellow in Genomics at the Innovative Genomics Institute led by Nobel Laureate Dr. Jennifer Doudna. Nabiha is also a TED speaker and co-creator of I Am A Scientist, an educational program running in 50 states that inspires children to explore science.
Megan & Alicia recap episode 17 of season 38 of MTV's The Challenge. The start of the 100-hour final is filled with injuries that would make Cellino & Barnes get back together... Watch The Challenge, Wednesdays at 8/7CT.Watch us live on Youtube(Duel Alliance Pod)Check us out on Twitter@DuellAlliancePod Alicia: @Ace_S5Megan: @meggsnhinesMake sure to rate, review, and subscribe wherever you get podcasts. While you're on the web, subscribe to our YouTube for episode clips and more.
Ross Cellino and Steve Barnes were two Buffalo-based lawyers who became the literal poster-men for personal injury advertising. They poured millions of dollars into ads that did more than just bring in clients: it turned the duo into household names and faces—at least in New York. In this episode, we're going to look at their rise and everything that happened after. It's a bumpy ride full of ambition, accidents and tragedy and at its center are two men who, for 25 years, wanted to be at the front of our minds when we got hurt, but who we didn't really notice until it all fell apart. We hear from Ross Cellino, Rich Barnes, Jeremy Kutner, John Fabian Witt, Trish Rich, Ken Kaufman, Mike Breen, and David Rafailedes. This podcast was written by Katie Shepherd. It was edited by Andrea Bruce and Willa Paskin. Decoder Ring is produced by Willa Paskin and Katie Shepherd. Derek John is Slate's Executive Producer of narrative podcasts. Merritt Jacob is Senior Technical Director. Thank you to Rachel Strom and Meryl Scheinman, host of Prank You. If you haven't please yet, subscribe and rate our feed in Apple Podcasts or wherever you get your podcasts. And even better, tell your friends. If you're a fan of the show and want to support us, consider signing up for Slate Plus. Slate Plus members get to listen to Decoder Ring without any ads. Their support is also crucial to our work. So please go to Slate.com/decoderplus to join Slate Plus today. Learn more about your ad choices. Visit megaphone.fm/adchoices
Ross Cellino and Steve Barnes were two Buffalo-based lawyers who became the literal poster-men for personal injury advertising. They poured millions of dollars into ads that did more than just bring in clients: it turned the duo into household names and faces—at least in New York. In this episode, we're going to look at their rise and everything that happened after. It's a bumpy ride full of ambition, accidents and tragedy and at its center are two men who, for 25 years, wanted to be at the front of our minds when we got hurt, but who we didn't really notice until it all fell apart. We hear from Ross Cellino, Rich Barnes, Jeremy Kutner, John Fabian Witt, Trish Rich, Ken Kaufman, Mike Breen, and David Rafailedes. This podcast was written by Katie Shepherd. It was edited by Andrea Bruce and Willa Paskin. Decoder Ring is produced by Willa Paskin and Katie Shepherd. Derek John is Slate's Executive Producer of narrative podcasts. Merritt Jacob is Senior Technical Director. Thank you to Rachel Strom and Meryl Scheinman, host of Prank You. If you haven't please yet, subscribe and rate our feed in Apple Podcasts or wherever you get your podcasts. And even better, tell your friends. If you're a fan of the show and want to support us, consider signing up for Slate Plus. Slate Plus members get to listen to Decoder Ring without any ads. Their support is also crucial to our work. So please go to Slate.com/decoderplus to join Slate Plus today. Learn more about your ad choices. Visit megaphone.fm/adchoices
Ross Cellino and Steve Barnes were two Buffalo-based lawyers who became the literal poster-men for personal injury advertising. They poured millions of dollars into ads that did more than just bring in clients: it turned the duo into household names and faces—at least in New York. In this episode, we're going to look at their rise and everything that happened after. It's a bumpy ride full of ambition, accidents and tragedy and at its center are two men who, for 25 years, wanted to be at the front of our minds when we got hurt, but who we didn't really notice until it all fell apart. We hear from Ross Cellino, Rich Barnes, Jeremy Kutner, John Fabian Witt, Trish Rich, Ken Kaufman, Mike Breen, and David Rafailedes. This podcast was written by Katie Shepherd. It was edited by Andrea Bruce and Willa Paskin. Decoder Ring is produced by Willa Paskin and Katie Shepherd. Derek John is Slate's Executive Producer of narrative podcasts. Merritt Jacob is Senior Technical Director. Thank you to Rachel Strom and Meryl Scheinman, host of Prank You. If you haven't please yet, subscribe and rate our feed in Apple Podcasts or wherever you get your podcasts. And even better, tell your friends. If you're a fan of the show and want to support us, consider signing up for Slate Plus. Slate Plus members get to listen to Decoder Ring without any ads. Their support is also crucial to our work. So please go to Slate.com/decoderplus to join Slate Plus today. Learn more about your ad choices. Visit megaphone.fm/adchoices
Ross Cellino and Steve Barnes were two Buffalo-based lawyers who became the literal poster-men for personal injury advertising. They poured millions of dollars into ads that did more than just bring in clients: it turned the duo into household names and faces—at least in New York. In this episode, we're going to look at their rise and everything that happened after. It's a bumpy ride full of ambition, accidents and tragedy and at its center are two men who, for 25 years, wanted to be at the front of our minds when we got hurt, but who we didn't really notice until it all fell apart. We hear from Ross Cellino, Rich Barnes, Jeremy Kutner, John Fabian Witt, Trish Rich, Ken Kaufman, Mike Breen, and David Rafailedes. This podcast was written by Katie Shepherd. It was edited by Andrea Bruce and Willa Paskin. Decoder Ring is produced by Willa Paskin and Katie Shepherd. Derek John is Slate's Executive Producer of narrative podcasts. Merritt Jacob is Senior Technical Director. Thank you to Rachel Strom and Meryl Scheinman, host of Prank You. If you haven't please yet, subscribe and rate our feed in Apple Podcasts or wherever you get your podcasts. And even better, tell your friends. If you're a fan of the show and want to support us, consider signing up for Slate Plus. Slate Plus members get to listen to Decoder Ring without any ads. Their support is also crucial to our work. So please go to Slate.com/decoderplus to join Slate Plus today. Learn more about your ad choices. Visit megaphone.fm/adchoices
En esta nueva entrega de "Libros Navegables", programa dirigido y presentado por Javier Muñiz, asistió la poeta gallega Yolanda Castaño para explicarnos que es "Materia", su último poemario editado en Edicións Xerais. Javier García Cellino nos habló de su poemario "Piedras", editado en Bajamar Editores. Víctor Manuel y Sabina pasaron por nuestros estudios para cantarnos algún tema y Julia de Burgos estuvo en el rincón poético. También hubpo las tradicionales secciones de efemérides, curiosidades, agenda cultural y mucho más.
From massive supply chain issues to wary investors, 2022 is turning out to be a tough year for biotech. But it's also a sector that's reshaping our lives, as we saw during the pandemic. So what are the most exciting opportunities in biotech right now? And where are the pitfalls? Cellino co-founder Nabiha Saklayen and Khosla Ventures partner Alex Morgan talk about making it through a downturn, machine learning, women in medicine, and the impact of outsiders.
Jake Becraft is co-founder and CEO of Strand Therapeutics, an emerging biotechnology company at the forefront of mRNA therapeutics. With colleagues at MIT's Synthetic Biology Center, he led the development of the world's first synthetic biology programming language for mRNA. Jake has been featured in Fierce Biotech, Bloomberg, and the Boston Business Journal, among others, for his vision and mission at Strand of applying this unique platform for real-world disease applications. Jake was recently named a Termeer Fellow and listed on MIT Technology Review's 35 Innovators Under 35 and Boston Business Journal's 40 Under 40. Outside of science, Jake is an active backcountry snowboarder and trains Brazilian Jiu Jitsu. Lex Rovner is the CEO and cofounder of 64x Bio, a spinout of Harvard Medical School and the Wyss Institute at Harvard University. Using novel high throughput genome engineering and screening technologies in a design loop with computational tools, 64x Bio is developing new ways of generating highly optimized cell lines for the manufacturing of viral vectors. These fundamental advances enable pharmaceutical and biotechnology companies to bring more lifesaving cell and gene therapies to patients by reducing the cost and complexity of manufacturing, a critical bottleneck in this multibillion dollar market. Lex was a postdoc in George Church's lab and cofounded the company along with George, Pam Silver, Jeff Way, and David Thompson. She received her Ph.D in molecular, cellular and developmental biology at Yale University. Josh Mandel-Brehm is President & Chief Executive Officer of CAMP4 Therapeutics and holds a dual appointment as entrepreneur partner with Polaris Partners. Mr. Mandel-Brehm previously held key business development and operations leadership roles at leading biotech companies. Most recently he served as part of the Business Development group at Biogen, where he led multiple strategic activities and corresponding transactions, which included expanding Biogen's non-malignant hematology franchise and overseeing seminal investments to enter the ophthalmology field. Mr. Mandel-Brehm also played an integral role advancing Biogen's gene therapy strategy, executing a series of external collaborations. Prior to Biogen, Mr. Mandel-Brehm held several roles of increasing responsibility at Genzyme as part of the business development group for the company's rare disease business unit. Mr. Mandel-Brehm earned a BA in Biology from Washington University in St. Louis and holds an MBA from the University of Michigan. Nabiha Saklayen is CEO & co-founder of Cellino. Cellino's proprietary technology makes personalized stem cell-derived therapies scalable for the first time. Nabiha was selected as a Pioneer in MIT Tech Review's 35 Innovators under 35 list for her patented inventions in cellular laser editing. She received her Ph.D. in Physics from Harvard University as a Howard Hughes Medical Institute (HHMI) International Fellow. She is also the inaugural Tory Burch Foundation Fellow in Genomics at the Innovative Genomics Institute led by Nobel Laureate Dr. Jennifer Doudna. Nabiha is also a TED speaker and co-creator of I Am A Scientist, an educational program running in 50 states that inspires children to explore science.
Dr. Nabiha Saklayen is CEO & co-founder of Cellino, a personalized regenerative medicine company developing an AI-guided laser editing platform for autologous cell-based therapies. Cellino's proprietary technology aims to make personalized stem cell-derived therapies scalable for the first time. Dr. Saklayen received her Ph.D. in Physics from Harvard University as a Howard Hughes Medical Institute (HHMI) International Fellow. In this episode, she joins Chris Patil to discuss autologous cell therapy and the strides Cellino has made in cell therapy using Machine Learning and laser technology. Dr. Saklayen talks about the challenges that come with autologous cell therapy, particularly in the manufacturing and cost aspect, and how Cellino infuses automation to make this procedure easier. She discusses how machine learning is integrated in the whole process and gives a brief insight into her career as a physicist and founding Cellino. She rounds up by discussing the future of Cellino and how Cellino strives to provide solutions in cell therapy that would change the world one patient at a time and at low cost. In this episode, you'll learn what cell therapy is and how Dr. Saklayen, through Cellino, is reshaping the world of cell therapy and biotech as we know it. Episode Highlights: ● What is cell therapy? ● Defining autologous cell therapies ● Examining the challenges with autologous cell therapy ● Cellino as a thought leader in the biotech industry ● The power of automation and laser therapy ● How machine learning contributes ● Dr. Saklayen's career journey ● Going from a blood cell to a stem cell - Sendai virus and episomal vectors ● How to determine the success of an IPSC induction ● The future of Cellino ● Targeting diseases of aging ● How Cellino is providing solutions in aging aspects ● Cell therapies over small molecules ● Cellino's goal for the next five years Quotes: “Cell therapy is a therapy where you make new cells for the patient and transplant them into the body to change the outcome of a disease or trajectory of a disease.” “It's about throughput. It's about yield. It's about consistency.” “The way we automate this process is by using machine learning algorithms that have been trained to look at images of cells and tell us which cells are high quality and which cells are not.” “It's really amazing to be able to tap into image-based machine learning algorithms and route the autonomous self-driving car industry towards advancing a lot of the neural nets that we're using in our training.” “I decided I want to be closer to real-world applications.” “Working together as an industry is going to be very important.” “Where we'd like to be in five years is we want to have our platform developed to a point where we can generate high quality patient specific cells in a reproducible manner, and do that for clinical doses.” Links: Email questions, comments, and feedback to podcast@bioagelabs.com Translating Aging on Twitter:https://twitter.com/BioAgePodcast ( @bioagepodcast) BIOAGE Labs Websitehttps://bioagelabs.com/ ( BIOAGELabs.com) BIOAGE Labs Twitterhttps://twitter.com/bioagelabs?lang=en ( @bioagelabs) BIOAGE Labshttps://www.linkedin.com/company/bioage-labs/ ( LinkedIn) https://techcrunch.com/2021/11/15/how-one-founder-tapped-lasers-to-automate-and-scale-stem-cell-production/ (Dr. Saklayen's TechCrunch Disrupt Talk) https://www.linkedin.com/in/nabihasaklayen/ (Dr. Saklayen's LinkedIn)
Find the Found feed here: https://pod.link/foundNot only is this week's guest the TechCrunch Disrupt 2021 Battlefield winner, but Nabiha Saklayen is also democratizing access to life-saving cell therapies by using—you guessed it—lasers. Nabiha is the co-founder and CEO of Cellino which is a company developing the tech to automate stem cell production that will lower the cost of cell therapies and increase the yield of viable cells. In this episode, Nabiha tells Jordan and Darrell how she built a start-up beginning with the tech and finding a business fit, her evolving leadership style, and why this work is crucial to the biomedical field.Take our listener survey and let us know a bit about yourself and what you think of FOUND.Connect with us:On TwitterOn InstagramVia email: found@techcrunch.comCall us and leave a voicemail at (510) 936-1618
Meryl calls a strip club, Cellino and Barnes (respectively), and more! Like rate and subscribe.
Not only is this week's guest the TechCrunch Disrupt 2021 Battlefield winner, but Nabiha Saklayen is also democratizing access to life-saving cell therapies by using—you guessed it—lasers. Nabiha is the co-founder and CEO of Cellino which is a company developing the tech to automate stem cell production that will lower the cost of cell therapies and increase the yield of viable cells. In this episode, Nabiha tells Jordan and Darrell how she built a start-up beginning with the tech and finding a business fit, her evolving leadership style, and why this work is crucial to the biomedical field. Take our listener survey and let us know a bit about yourself and what you think of FOUND.Connect with us:On TwitterOn InstagramVia email: found@techcrunch.comCall us and leave a voicemail at (510) 936-1618
While cell therapies have been advancing rapidly, therapies that rely on taking a patient's own cells, altering them, and reinfusing them back into a patient are costly. Part of the reason why is that the process for doing this is labor intensive. Cellino has developed a platform for producing personalized autologous cell therapies in an automated and scalable fashion. We spoke to Marinna Madrid, co-founder and vice president of product, for Cellino, about the company's platform technology for cell-based therapies, how it works, and why it may help enable a new era of personalized regenerative therapies.
Part 2 in our 2 part series about the rise and fall of personal injury attorneys Cellino and Barnes. All the ads we talk about in this episode here: https://youtu.be/oZGPHD1i6R4 Sources: https://nymag.com/intelligencer/article/cellino-and-barnes-breakup.html https://buffalonews.com/news/local/cellino-on-barnes-all-i-can-think-about-is-the-good-times-all-the-milestones/article_3bde2f98-0991-11eb-ae64-239d3482042a.html https://www.vox.com/the-goods/2019/8/8/20758876/local-jingle-business-cellino-barnes-ad-history https://www.nytimes.com/2020/10/08/business/media/stephen-barnes-dead.html https://nypost.com/2017/10/17/cellino-says-stingy-barnes-is-opposed-to-employee-benefits/
Part 1 in our 2 part series about the rise and fall of personal injury attorneys Cellino and Barnes. All the ads we talk about in this episode here: https://youtu.be/EIA3rkBnlps Sources: https://nymag.com/intelligencer/article/cellino-and-barnes-breakup.html https://buffalonews.com/news/local/cellino-on-barnes-all-i-can-think-about-is-the-good-times-all-the-milestones/article_3bde2f98-0991-11eb-ae64-239d3482042a.html https://www.vox.com/the-goods/2019/8/8/20758876/local-jingle-business-cellino-barnes-ad-history https://www.nytimes.com/2020/10/08/business/media/stephen-barnes-dead.html https://nypost.com/2017/10/17/cellino-says-stingy-barnes-is-opposed-to-employee-benefits/
Meryl calls a former Real Housewife of New York City, Cellino and Barnes, a chiropractor, Trump Chicago, and more! Like, rate and subscribe wherever you get your podcasts.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Jennifer Friel Goldstein is the Managing Partner for Life Science & Healthcare Practice @ SVB Capital and is a founding member of Venture Forward, a nonprofit that provides resources and education toward developing a diverse, equitable and inclusive venture capital (VC) ecosystem. She is also an advisory board member of Springboard Enterprises and the Women's Health Innovation Coalition. Jennifer has more than 20 years of experience in the VC and startup market segments, including leading and building several teams over the past eight years at Silicon Valley Bank. Before that, she was a director on Pfizer's VC team, where she helped lead or co-lead investments into several life sciences companies. She also led fund of funds investment decisions and independently managed Pfizer's $250 million private equity (PE) portfolio. Jennifer served as a consultant on PE deals across Europe while at Bain & Company and held operational and research roles at Chiron, Genelabs, and Genencor. Jennifer graduated magna cum laude with a bachelor's degree in bioengineering and a master's degree in biotechnology from the University of Pennsylvania. She holds an MBA from the Wharton School, where she was named a Joseph Wharton Fellow. She also serves as an independent director at Alexandria Real Estate Equities, Inc. Jennifer lives in the Bay Area with her husband and their twin children.W/ Special Guest Host: Nabiha Saklayen - Cofounder & CEO @ CellinoNabiha Saklayen is a bio-inspired physicist and Co-Founder & CEO @ Cellino. Nabiha launched Cellino to converge physics, biology, and machine learning to enable paradigm shifts in autologous regenerative medicine. Nabiha was recognized as a Pioneer in MIT Tech Review's 35 Innovators under 35 list for her inventions in laser-based delivery methods and is on the 2019 Forbes under 30 List for Healthcare. She received her Ph.D. in Physics from Harvard University as an HHMI International Fellow. She made significant scientific contributions to the field of pulsed-laser delivery to cells, with several peer-reviewed papers published, patents pending, and grants awarded. Nabiha grew up in Saudi Arabia, Bangladesh, Germany, and Sri Lanka and currently lives in Boston, MA.Cellino is on a mission to make personalized, autologous cell therapies accessible for patients. Stem cell-derived regenerative medicines are poised to cure some of the most challenging diseases within this decade, including Parkinson's, diabetes, and heart disease. Patient-specific cells provide the safest, most effective cures for these indications. However, current autologous processes are not scalable due to extensive manual handling, high variability, and expensive facility overhead. Cellino's vision is to make personalized regenerative medicines viable at large scale for the first time. Cellino's platform combines label-free imaging and high-speed laser editing with machine learning to automate cell reprogramming, expansion, and differentiation in a closed cassette format, enabling thousands of patient samples to be processed in parallel in a single facility.Thank you for listening!BIOS (@BIOS_Community) unites a community of Life Science innovators dedicated to driving patient impact. Alix Ventures (@AlixVentures) is a San Francisco based venture capital firm supporting early stage Life Science startups engineering biology to create radical advances in human health.Music: Danger Storm by Kevin MacLeod (link & license)
Meryl pranks a butterfly lover, the Cellino law firm, an unsuspecting student, and more! Like, rate, and subscribe wherever you get your podcasts.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this Podcast episode we return to the topic of stem cells. We discussed that autologous stem cells can be a powerful therapeutic tool for Parkinson's disease in our interview with Professor Jeanne Loring. The challenge however is to manufacture those therapies at scale. Our guest on this episode is taking a major step in alleviating this hurdle. Meet Nabiha Saklayen, the co-founder and CEO of Cellino, a company that merges stem cell biology, laser physics and machine learning to make autologous stem cell therapies possible. Together with Nabiha, we discussed:◦ Her personal career story from physics to biotech◦ Role of finding product/market fit early in a deep tech startup journey◦ Importance of founding team for any startup◦ Challenges in manufacturing of autologous cell therapeutics◦ Cellino's approach for automated selection and expansion of iPSCs◦ Applications of stem cells in drug discovery◦ The future of personalized stem cell therapiesGet in touch with Nabiha:◦ LinkedIn: https://www.linkedin.com/in/nabihasaklayen/◦ Twitter: @nabsicle ◦ Website (Cellino): https://www.cellinobio.com/Make sure to download the full show notes with our guest's bio, links to their most notable work, and our recommendations for further reads on the topic of the episode at pmedcast.com
Marinna Madrid is a co-founder of Cellino, a startup that leverages AI, robotics, and laser-editing to develop and manufacture stem cell therapies at scale. She obtained her Ph.D in Physics from Harvard and was named a Forbes Top 30 under 30 in healthcare.
Dr. Marinna Madrid is co-founder of Cellino, an early-stage biotechnology company seeking to make personalized, autologous cell therapies viable at large scale for the first time.
Mike Vecchione and Shannon Lee start off the new podcast "Mike Vecchione Investigates" by doing a deep dive into a case that Mike just can't seem to let go of - Cellino & Barnes - how they began working together, their rise to fame, how resentment started to build, their eventual break-up and then finally the untimely death of Steve Barnes. Who do you think is at fault?(Air Date: April 1st, 2021)Merchandise is available at https://podcastmerch.com/collections/no-disrespectYou can watch Mike Vecchione Investigates LIVE for FREE every Thursday at 3pm ET at GaSDigitalNetwork.com/LIVEOnce you're there you can sign up at GaSDigitalNetwork.com with promo code: MVI for a 14-day FREE trial with access to every No Disrespect and Mike Vecchione Investigates episode show ever recorded! On top of that you'll also have the same access to ALL the shows that GaS Digital Network has to offer!Follow the whole show on social media!Mike VecchioneTwitter: https://www.twitter.com/comicmikevInstagram: https://www.instagram.com/comicmikevShannon LeeTwitter: https://www.twitter.com/imshannonleeInstagram: https://www.instagram.com/shannonlee6982GaS Digital NetworkTwitter: https://twitter.com/gasdigitalInstagram: https://www.instagram.com/gasdigital/
Quick, what was the phone number for Cellino & Barnes? A lot of you probably got that right immediately. But the firm split up a few years ago and the two entities it spawned have dueling jingles now. Which came out on top? Joe and Kathryn also discuss Davis Polk's extra bonus program and what it means for Biglaw and attorney wellness generally. Also, Texas AG Ken Paxton may want to take a break from social media for awhile and attorneys still need to hit mute on Zoom more often. Special thanks to our sponsors, LexisNexis® InterAction®, Lexicon and Nota.
Quick, what was the phone number for Cellino & Barnes? A lot of you probably got that right immediately. But the firm split up a few years ago and the two entities it spawned have dueling jingles now. Which came out on top? Joe and Kathryn also discuss Davis Polk's extra bonus program and what it means for Biglaw and attorney wellness generally. Also, Texas AG Ken Paxton may want to take a break from social media for awhile and attorneys still need to hit mute on Zoom more often. Special thanks to our sponsors, LexisNexis® InterAction®, Lexicon and Nota.
Hoy comenzamos el programa entevistando al director gerente del Area VIII Bernabé Fernández sobre la evolución de la pandemia en el Valle del Nalón. También hablamos con el escritor langreano Javier G. Cellino de su nueva novela "El cuarto hombre".
Leeds United are one of the most decorated football clubs in England with a dazzling history. This episode we cover some of the stories that Leeds fans wish would have been kept under wraps. Nick Harris opens the door to some of the most outrageous years in history books of Leeds United. We are talking the attempted sacking of Brian McDermott at half time via the phone, outrageous spending habits and goldfish monthly wages?! From Peter Ridsdale's financial gambles, through the turbulent Ken Bates era, the infamous GFH takeover and the crazy Cellino times, we pull back the curtain on one of the most unbelievable stories in football ownership.
Plumbing Marketing Podcast - Tips, Ideas & Strategies for Marketing your Plumbing Company Online
Listen in as we interview Lucas Cellino from Cellino Plumbing & HVAC. They are a full-service Plumbing & HVAC company serving the greater Buffalo, NY area. Their operation has 23 trucks and is growing by over 35% year over year. Lucas shares some amazing insights on how they keep their phone ringing, trucks running & […]
Leeds United's Season Is Over.......Well until they drag themselves into a regulation battle. LUFC'S Scott Wooton got FA Cup fever on Saturday, he got so ill from his fever. He was so dizzy with excitement and some how managed to put the ball, in his own net. Watford 1 - 0 Leeds - FULL TIME (Thanks Scott) Fans around the world laughed at this crazy mistakes. Leeds fans did not laugh. The sad reality of the Wooton own-goal was, we knew he was capable of something this bad. Leeds United Fan and The Football Hour Presenter @alexmearns7 was there to witness this goal and shockingly poor performance. Listen to his review of the match, the goal, the puppet(Steve Evans) and the puppet master(Cellino). This season may possibly have gone from bad............to relegation