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What does it actually take to build a brand that survives the modern internet? In this episode, we sit down with Ankit, a seasoned marketing agency founder, to pull back the curtain on the messy, unglamorous reality of Indian business.Ankit Saraf is the Founder of Meraqi Digital, one of Eastern India's leading and fastest-growing independent digital marketing consulting agencies based in Kolkata. A visionary marketer, Ankit holds a Master's in Advertising and Design from the University of Leeds and brings over 13 years of cross-continental experience to the table. Before turning entrepreneur, he spent nearly a decade in London working with top-tier global agencies, leading highly impactful digital portfolios for iconic multinational giants including Budweiser, AB InBev Global, Sainsbury's, Procter & Gamble, and Olay. Driven by a desire to bring world-class marketing standards and international work culture to his hometown, he returned to India in 2016. Launching Meraqi Digital under challenging circumstances with an initial capital of just ₹20,000 in a small room, Ankit scaled the business rapidly, crossing ₹1 crore in revenue within 2.5 years. Today, he leads a robust, multi-award-winning team of over 40 digital natives, orchestrating digital transformations and growth strategy mandates for heavyweights like the RP-Sanjiv Goenka Group, WOW! Momo, Emami Group, and ITC Limited.From the toxic trap of chasing short-term viral trends to why legacy "boring" businesses quietly make the most money in India, this conversation is a masterclass for every modern founder, D2C marketer, and next-gen family business owner. If you are tired of surface-level startup advice and want real, data-backed insights on what actually drives sales and consumer sentiment, this episode is for you.Key Takeaways From This Episode:The Quick Commerce Illusion: Why the highly visible D2C brands you see all over social media are secretly bleeding money under the hood, while unsexy traditional businesses are booking massive profits.The Pan-India Scaling Trap: Why burning limited capital to target all of India on day one is a recipe for failure, and how to successfully build hyper-local validation first.Next-Gen Family Business Friction: A practical, zero-BS guide for young founders on how to introduce digital marketing to traditional parents without disrupting the legacy systems that already work.The "Fickle" Modern Marketer: Why chasing every single internet algorithm trend is ruining brand identity, and how legacy giants maintain deep consumer connections over decades.The Reality of AI in Agencies: How artificial intelligence is actively changing agency workflows, why it excels at boring data crunching, and why it will never replace raw human creative emotion.
“We need to develop better theories of why the other side believes what they do. Having an accurate theory includes recognizing if somebody is a psychopath — but also recognizing that psychopaths are rarer than we think.” — Audun Dahl If you're not a liberal at twenty, you have no heart; if you're not a conservative at forty, you have no head. While this sounds like an annoying cliché (especially to people under forty), it does recognize that our moral views change. But, as the Cornell psychologist Audun Dahl argues in his new book Between Fixed and Fickle: Why Our Moral Views Keep Changing, the most interesting question is why our moral principles always seem in flux. Why people who say cheating is wrong cheat. Why people who say violence is wrong turn a blind moral eye to their own insurrections. Dahl is a psychologist, not a moralist. He is not interested in what we should believe, but in what we think we believe. His central finding is that human morality is neither fixed nor fickle. People change their moral views when they believe they have good reasons to — reasons they can, indeed, articulate. The problem isn't hypocrisy per se. It's that we struggle to understand why the other side believes what it does. In morally polarised societies like contemporary America, we over-attribute psychopathy to political opponents. Most Republicans and most Democrats do have genuine moral commitments. But they are just different principles, applied to parallel moral hierarchies. Rather than morality perhaps, we need more empathy. Don't judge. Understand. Five Takeaways • Two Kinds of Moral Change: Dahl identifies two forms of moral change that should trouble us. Situational moral change: people espouse one principle and act against it in a specific situation — the person who says cheating is wrong and cheats on an exam, the January 6th rioter who says violence is wrong. Historical moral change: the same principles coexisting with practices that contradict them — Thomas Jefferson proclaiming inalienable rights while enslaving hundreds. Both are not simply hypocrisy: they reflect the genuine messiness of moral life, where competing principles create constant conflict. • Morality Emerges in the First Three Years of Life: Dahl's most striking empirical finding: by around age three, virtually all children develop an intrinsic concern with how we ought to treat other sentient beings. It is not taught as an external rule. It emerges. A three-year-old will say: it's wrong to harm others, you shouldn't steal. No other animal acquires this. It is a uniquely human characteristic. The question is not whether people have moral commitments — almost everyone does. The question is how those commitments interact with other concerns, pressures, and competing principles. • We Over-Attribute Psychopathy to the Other Side: One of the most robustly documented findings in political psychology: Republicans and Democrats don't merely think the other side is wrong. They think the other side is evil — likely to condone things they would never condone. Research shows both sides significantly over-estimate the other's extremism and moral depravity. Dahl's prescription: develop better theories of why the other side believes what it does. An accurate theory includes recognising genuine psychopaths and bad actors when they exist. It also includes recognising that they are rarer than we think. • Jefferson, Epstein, and the Exceptions: Two historical anchors. Jefferson: the author of the Declaration of Independence's inalienable rights, who enslaved hundreds. The question is not whether he was a hypocrite — he clearly was — but how someone could hold both positions simultaneously. The answer Dahl finds most compelling: conflicting moral principles applied with different weights in different contexts, not the absence of moral concern. Epstein: the opposite case, a man who concealed an absence of moral concern behind a veneer of respectability. The lesson: some people genuinely lack it, but they are exceptions. • Elbow Room: The Hilary Mantel Closer: Dahl's two wishes for a more moral world. First: that we understand why the other side disagrees. Second: that we have more “elbow room” — the phrase from Hilary Mantel's Cromwell trilogy — to make decisions based on what we actually think is right rather than what we need to do to survive. Machiavelli and Cromwell operated in a world where survival left almost no room for principled action. If that is becoming our world again, the prospects for moral progress are bleak. Dahl is cautiously hopeful. The creative, restless energy of each new generation — willing to say this is unjust, this is unfair — is what abolished slavery. It is what drives moral change still. About the Guest Audun Dahl is Associate Professor of Psychology at Cornell University. He is the author of Between Fixed and Fickle: Why Our Moral Views Keep Changing (Harvard University Press, April 2026). He grew up in Norway and is based in Ithaca, New York. References: • Between Fixed and Fickle: Why Our Moral Views Keep Changing by Audun Dahl (Harvard University Press, April 2026). • Hilary Mantel, Wolf Hall trilogy — cited by Dahl as capturing the “elbow room” problem of moral action under survival pressure. • Viktor Frankl, Man's Search for Meaning — referenced in the same context as Mantel. • Episode 2906: Dylan Gottlieb on Yuppies — the companion episode on how professional class morality was shaped by competing incentives. About Keen On America Nobody asks more awkward questions than the Anglo-American writer and filmmaker Andrew Keen. In Keen On America, Andrew brings his pointed Transatlantic wit to making sense of the United States — hosting daily interviews about the history and future of this now venerable Republic. With nearly 2,900 episodes since the show launched on TechCrunch in 2010, Keen On America is the most prolific intellectual interview show in the history of podcasting. WebsiteSubstackYouTubeApple PodcastsSpotify Chapters: (00:31) - The Churchill/Adams quote: liberal at 20, conservative at 40 (02:08) - Dahl's Norwegian grandpa and the disputed attribution (02:30) - Two kinds of troubling moral change: situational and historical (03:10) - Jefferson's Declaration of Independence and his enslaved peopl...
On today's Rugby Daily, Susanna Mollen brings you reactions from across the URC and the Women's Six Nations, as well as news of a new scrum coach in Connacht. Rugby Daily is on Off The Ball with Bank Of Ireland | #NeverStopCompeting
Fickle emotions, finite perspective, and mis-ordered desires are your greatest adversaries when seeking truth. Join One Missoula Church Online for our weekly service, or if you're in Missoula, join us live and in person on Sundays at 9 and 10:30AM at 1714 South Reserve Street. Search the iOS App Store or Android Play Store for "One Missoula Church" - Sermon notes/bulletin- Download previous messages for viewing at your convenience. Want to get connected? Fill out our Connection Card!: https://onemissoulachurch.com/connect Would you like to help reach Missoula? Support the Mission!: https://onemissoulachurch.com/give
March 29, 2026, The Rev. Dr. Brian LaysScripture: Isaiah 50:4-9a and Matthew 21:1-11
ਆਸਾ ਸ੍ਰੀ ਕਬੀਰ ਜੀਉ ਕੇ ਦੁਪਦੇੴ ਸਤਿਗੁਰ ਪ੍ਰਸਾਦਿ ॥ਹੀਰੈ ਹੀਰਾ ਬੇਧਿ ਪਵਨ ਮਨੁ ਸਹਜੇ ਰਹਿਆ ਸਮਾਈ ॥ ਸਗਲ ਜੋਤਿ ਇਨਿ ਹੀਰੈ ਬੇਧੀ ਸਤਿਗੁਰ ਬਚਨੀ ਮੈ ਪਾਈ ॥੧॥ ਹਰਿ ਕੀ ਕਥਾ ਅਨਾਹਦਬਾਨੀ ॥ ਹੰਸੁ ਹੁਇ ਹੀਰਾ ਲੇਇ ਪਛਾਨੀ ॥੧॥ ਰਹਾਉ ॥ ਕਹਿ ਕਬੀਰ ਹੀਰਾ ਅਸ ਦੇਖਿਓ ਜਗ ਮਹ ਰਹਾ ਸਮਾਈ ॥ ਗੁਪਤਾ ਹੀਰਾ ਪ੍ਰਗਟ ਭਇਓ ਜਬਗੁਰ ਗਮ ਦੀਆ ਦਿਖਾਈ ॥੨॥੧॥੩੧॥ਆਸਾ ਸ੍ਰੀ ਕਬੀਰ ਜੀਉ ਕੇ ਦੁਪਦੇੴ ਸਤਿਗੁਰ ਪ੍ਰਸਾਦਿ ॥ਜਦੋਂ (ਜੀਵ-) ਹੀਰਾ (ਪ੍ਰਭੂ-) ਹੀਰੇ ਨੂੰ ਵਿੰਨ੍ਹ ਲੈਂਦਾ ਹੈ (ਭਾਵ, ਜਦੋਂ ਜੀਵ ਪਰਮਾਤਮਾ ਦੇ ਚਰਨਾਂ ਵਿਚ ਸੁਰਤ ਜੋੜ ਲੈਂਦਾ ਹੈ) ਤਾਂ ਇਸ ਦਾ ਚੰਚਲ ਮਨ ਅਡੋਲਅਵਸਥਾ ਵਿਚ ਸਦਾ ਟਿਕਿਆ ਰਹਿੰਦਾ ਹੈ । ਇਹ ਪ੍ਰਭੂ-ਹੀਰਾ ਐਸਾ ਹੈ ਜੋ ਸਾਰੇ ਜੀਆ-ਜੰਤਾਂ ਵਿਚ ਮੌਜੂਦ ਹੈ�ਇਹ ਗੱਲ ਮੈਂ ਸਤਿਗੁਰੂ ਦੇ ਉਪਦੇਸ਼ ਦੀਬਰਕਤ ਨਾਲ ਸਮਝੀ ਹੈ ।੧।ਪ੍ਰਭੂ ਦੀ ਸਿਫ਼ਤਿ-ਸਾਲਾਹ ਨਾਲ ਤੇ ਇੱਕ-ਰਸ ਗੁਰੂ ਦੀ ਬਾਣੀ ਵਿਚ ਜੁੜ ਕੇ ਜੋ ਜੀਵ ਹੰਸ ਬਣ ਜਾਂਦਾ ਹੈ ਉਹ (ਪ੍ਰਭੂ-) ਹੀਰੇ ਨੂੰਪਛਾਣ ਲੈਂਦਾ ਹੈ (ਜਿਵੇਂ ਹੰਸ ਮੋਤੀ ਪਛਾਣ ਲੈਂਦਾ ਹੈ) ।੧।ਰਹਾਉ।ਕਬੀਰ ਆਖਦਾ ਹੈ�ਜੋ ਪ੍ਰਭੂ-ਹੀਰਾ ਸਾਰੇ ਜਗਤ ਵਿਚ ਵਿਆਪਕ ਹੈ, ਜਦੋਂ ਉਸ ਤਕ ਪਹੁੰਚਵਾਲੇ ਸਤਿਗੁਰੂ ਨੇ ਮੈਨੂੰ ਉਸ ਦਾ ਦੀਦਾਰ ਕਰਾਇਆ, ਤਾਂ ਮੈਂ ਉਹ ਹੀਰਾ (ਆਪਣੇ ਅੰਦਰ ਹੀ) ਵੇਖ ਲਿਆ, ਉਹ ਲੁਕਿਆ ਹੋਇਆ ਹੀਰਾ (ਮੇਰੇ ਅੰਦਰ ਹੀ) ਪ੍ਰਤੱਖਹੋ ਗਿਆ ।੨।੧।੩੧।AASAA OF KABEER JEE, DU-PADAS:ONE UNIVERSAL CREATOR GOD. BY THE GRACE OF THE TRUE GURU:When the Diamond of the Lord pierces the diamond of my mind, the fickle mind waving in the wind is easily absorbed into Him. This Diamond fills all with Divine Light; through the True Guru�s Teachings, I have found Him. || 1 || The sermon of the Lord is the unstruck, endless song. Becoming a swan, one recognizes the Diamond of the Lord. || 1 || Pause || Says Kabeer, I have seen such a Diamond, permeating and pervading the world. The hidden diamond became visible, when the Guru revealed it to me. || 2 || 1 || 31 ||
Top 10 Mental Skills Every Athlete Needs to Master Grab the list here: https://t.co/yoaXVzPw9H-This Episode is Brought to you by:Champions Adjust Use code CAPod10 for 10% OFF
When we face difficulties in our lives, it's easy to want to go back to the past when life seemed easier. God wants to use those difficulties to grow our faith in Him so that we can receive His spiritual blessings that we would never have if we went back.
When we face difficulties in our lives, it's easy to want to go back to the past when life seemed easier. God wants to use those difficulties to grow our faith in Him so that we can receive His spiritual blessings that we would never have if we went back. To support this ministry financially, visit: https://www.oneplace.com/donate/640/29?v=20251111
The book of Acts shows how one prayer, one witness, and one act of courage can create a ripple that reaches nations. From prison cells to shipwrecks to Rome itself, God uses ordinary believers to spread an unstoppable gospel. What ripple might God start through you?
The book of Acts shows how one prayer, one witness, and one act of courage can create a ripple that reaches nations. From prison cells to shipwrecks to Rome itself, God uses ordinary believers to spread an unstoppable gospel. What ripple might God start through you?
Fickle Faith March 4, 2026 by Bible Baptist Church - Brookings, SD
Title: True Lies: Marriage is Fickle Preacher: Jamie Dunlop Series: True Lies Passage: Ephesians 5:22-33
In this episode Ashea sits down for a virtual lunch with Richard Hilton (Nile Rodgers & Chic) & Steve DeMott (Tribe Collective) where they discuss the fickle lives of creatives, telling stories, working with emotions and the importance of good milk!About Our Guests:Steve DeMott: Producer, engineer, songwriter, and musician who has worked with the Grammy nominated Tribe collective Richard Hilton: Musician and producer well known for his work with Nile Rodgers and Chic
We hope you enjoy today's Scripture reading and devotional aimed at equipping you for moral and spiritual transformation. Today's Bible reading is Deuteronomy 26:16–19. To read along with the podcast, grab a print copy of the devotional at https://www.crossway.org/books/daily-strength-hcj/. Follow us on social media to stay up to date: Instagram Facebook Twitter
Faithful, God, Bible, Parkwood, Barefield
In this episode, Tara Fickle, an associate professor of Asian American studies, delves into the intersection of race and gaming, introducing the concept of ludo-orientalism. She explores how racial stereotypes shape perceptions of Asian gamers and discusses the role of gender in e-sport culture.Edited by: Meibel Dabodabo
Paul tells Timothy about the people who abandoned him as well as the one man that stood by his side named Onesiphorus. He will serve as a good example for Timothy to follow, and our students should follow it today!
Music by:Knifewing - Talk To The Children (One Spirit, Two Worlds)Tonemah - Mary Might (The Ghosts Of St. Augustine)
Listen as Pastor Eugene Oldham preaches a sermon called The Dream Team & The Fickle Church from 2 Cor. 8:16-9:5.
Send us a textA romantic anniversary trip to a secluded cabin turns sinister when a dark presence reveals itself, forcing old friends to confront their podcast's haunting past. On Episode 700 of Trick or Treat Radio we eschew the normal pomp and circumstance of a milestone show for our normal format and continue on with December Double Feature Cram Jam. This week we discuss films from two of our favorite directs; Keeper from Osgood Perkins, and Eddington from Ari Aster! We also get inducted into the 700 Club, react to trailers for the films; Amityvillenado and 28 Years Later: The Bone Temple, and are faced with the ghosts of 2020 all over again. So grab your jar of honey, post an angry rant online, and strap on for the world's most dangerous podcast!Stuff we talk about: Fickle horror fans, Hellraiser, dinner scene, smoking without burning your mouth, Trish Stratus, scenes in horror that drive you nuts, gimmick as a personality, the 700 Club, fitness sponsors, snikts and krakadooms, roman chairs and russian fingers, gathering of the Juggalos, fluff it up, 20,000 Leagues Under the Sea, James Mason, The 7th Voyage of Sinbad, Scars of Dracula, Christopher Lee, Hellbound: Hellraiser II, The Bone Snatcher, Death Machine, Pulse 3, Solomon Kane, Hazmat, Evil Remains, Estella Warren, Corey Haim, The Lost Boys, Dario Argento's Trauma, King Kong, John Northpole, Mega Huge Pictures, Amityvillenado, 28 Years Later: The Bone Temple, Nia DeCosta, Danny Boyle, gratuitous gratuity, Bee Gees, Barry Gibb - the handsome one, Keeper, Osgood Perkins, the 700 Club, nefarious, Tatiana Maslany, breaking the cycle of patriarchy, Ready or Not, folk horror, body horror, Guillermo del Toro, subtle satisfaction, films flipping the script, Joaquin Phoenix, Deirdre O'Connell, Emma Stone, Pedro Pascal, Austin Butler, Ari Aster, Midsommar, Hereditary, Beau is Afraid, Eddington, Christopher Nolan, Odyssey, WWE vs AEW, Ben Affleck, James Gunn's DCU vs Zack Snyder's DCEU, Honey Ripple head cream, and Before and Aster.Support us on Patreon: https://www.patreon.com/trickortreatradioJoin our Discord Community: discord.trickortreatradio.comSend Email/Voicemail: mailto:podcast@trickortreatradio.comVisit our website: http://trickortreatradio.comStart your own podcast: https://www.buzzsprout.com/?referrer_id=386Use our Amazon link: http://amzn.to/2CTdZzKFB Group: http://www.facebook.com/groups/trickortreatradioTwitter: http://twitter.com/TrickTreatRadioFacebook: http://facebook.com/TrickOrTreatRadioYouTube: http://youtube.com/TrickOrTreatRadioInstagram: http://instagram.com/TrickorTreatRadioSupport the show
On this episode, Micah and Ryan break down one of the biggest events of 2025, John Cena's Last Match! Including the entire card, what legacy John Cena leaves, and more!Thanks for tuning in, make sure to check out our socials so you know the next time we're scooping and slamming: linktr.ee/scoopslammedpod
As we continue to follow the missions of Paul and Barnabas, Fr. Mike highlights the fickle nature of humanity and the futility of striving for the praise of men. He also encourages us to remain courageous in the tribulations we face, finding strength in other believers, and running toward the eternal and imperishable goal of salvation. Today's readings are Acts 14, 1 Corinthians 9-10, and Proverbs 28:7-9. For the complete reading plan, visit ascensionpress.com/bibleinayear. Please note: The Bible contains adult themes that may not be suitable for children - parental discretion is advised.
3pm - DANNY WESTNEAT ON A FICKLE SEATTLE // TRUMP PROPOSES 50 YEAR MORTGAGES AND TARIFF REBATES // POP-COUNTY MUSIC’S PANDERING FORMULAS
김영철의 파워FM - 진짜 영국식 영어 510회 - 날씨가 오락가락해! = The weather is so fickle!
5pm - PHONE GUEST - DANNY WESTNEAT - SEATTLE TIMES: Seattle shows it’s a fickle city // VIDEO GUEST - KATE CRAMER: She saved a baby goat. Now they travel the country, share a bed // LETTERS
People are so easily influenced--their thinking weak. Look what happens here in Acts chapter 14: first the people are hailing them as gods, then they are dragging them out to stone them! Weak thinking--how's yours?
Inside the AI Classroom: Dan & Ray's Big AI-in-Education Download In this fast-paced news roundup, Dan and Ray dive head-first into the latest research and developments shaping AI in education. From MIT's Perspectives for the Perplexed guide for schools, to McKinsey's take on "agentic AI," to Google's LearnLM experiments with AI-powered textbooks, the duo unpack what every educator needs to know right now. They explore what's happening inside classrooms, universities, and edtech labs — including new findings on AI literacy, evolving assessment design, and why "policing AI use" misses the point. Plus, they debate the rise of AI-integrated browsers like ChatGPT Atlas, what it means for assessment integrity, and how tools like Microsoft Copilot are reshaping both teaching and admin work. It's the ultimate AI-in-education briefing — thoughtful, fast, and full of insights (and laughs) from two of the field's most passionate voices. Here's all the links to news and research mentioned in the podcast (and, most importantly) the Two Ronnies Fork Handles sketch! Fork Handles https://youtu.be/sO6EE1xTXmw?si=5Iix8Jo_xiZCRVCn News MIT "Guide to AI in Schools: Perspectives for the Perplexed" https://tsl.mit.edu/ai-guidebook/ https://tsl.mit.edu/wp-content/uploads/2025/08/GuideToAIInSchools.pdf One year of agentic AI: Six lessons from the people doing the work https://www.mckinsey.com/capabilities/quantumblack/our-insights/one-year-of-agentic-ai-six-lessons-from-the-people-doing-the-work OpenAI Atlas (and Perplexity Comet) https://openai.com/index/introducing-chatgpt-atlas/ An Opinionated Guide to Using AI Right Now https://www.oneusefulthing.org/p/an-opinionated-guide-to-using-ai Google "Learn Your Way" pilot https://learnyourway.withgoogle.com/ Towards an AI-Augmented Textbook https://arxiv.org/abs/2509.13348 Experimentally Testing AI-Powered Content Transformations on Student Learning https://arxiv.org/abs/2509.18664 PEW Research into AI attitudes around the world https://www.pewresearch.org/global/2025/10/15/how-people-around-the-world-view-ai/ Copilot in Windows https://blogs.windows.com/windowsexperience/2025/10/16/making-every-windows-11-pc-an-ai-pc/ Copilot consumer updates https://www.youtube.com/watch?v=j4jXM8yTdnQ&feature=youtu.be M365 Copilot Education updates https://www.microsoft.com/en-us/education/blog/2025/10/designing-microsoft-365-copilot-to-empower-educators-students-and-staff/?msockid=0a3b30f5f88b6061226e245bf9b96140 BBC: The lecturers learning to spot AI misconduct https://www.bbc.com/news/articles/c2kn3gn8vl9o UNE are rolling out their Madgwick AI system to all students https://www.linkedin.com/posts/aaronbdriver_aiineducation-highered-enterpriseai-activity-7378920493543845888-aZ3I Research The Bubble and Burner Model of AI-Infusion: A Framework for Teaching and Learning https://papers.ssrn.com/sol3/papers.cfm?abstract_id=5501341 Firm or Fickle? Evaluating Large Language Models Consistency in Sequential Interactions https://aclanthology.org/2025.findings-acl.347/ GASLIGHTBENCH: Quantifying LLM Susceptibility to Social Prompting, https://openreview.net/forum?id=0BYRYwGCbK What does 'good teaching' mean in the AI age? https://journals.sfu.ca/jalt/index.php/jalt/article/view/3649 How university students work on assessment tasks with generative artificial intelligence: matters of judgement https://www.tandfonline.com/doi/full/10.1080/02602938.2025.2570328 AI Knows Best? The Paradox Of Expertise, Ai-Reliance, And Performance In Educational Tutoring Decision-Making Tasks http://arxiv.org/pdf/2509.16772v1
10.22.25, Kevin Sheehan, Producer Max and callers list what they are buying and selling going into week 8 of the NFL season and Kevin goes on a rant about Commanders' fans turning on Adam Peters already.
I just want to go on record in saying that this 'F.I.C.K.L.E.' thing, I am not in support of it. On to the show, we talk about the shutdown and Bad Bunny. Worth the listen.
See all the Healthcasts at https://www.biobalancehealth.com/healthcast-blog If you ever doubted your doctor because she wrote a script that you later “Googled” and found was not FDA approved, I hope you trusted your doctor enough to realize that she wouldn't recommend any medication that would hurt you…. What is an unapproved use of a drug, also called “off-label”? Unapproved use of an approved drug is often called “off-label” use. This term can mean that the drug is: Used for a disease or medical condition that it is not approved to treat, such as when a chemotherapy is approved to treat one type of cancer, but healthcare providers use it to treat a different type of cancer. The drugs that are not approved by the FDA, yet are commonly used, have been used for decades before the 1964 law that required new drugs to go through extensive and very expensive testing before their release to the public. The operative word is NEW DRUGS AFTER 1964. Today I will talk about the safety of non-FDA approved drugs because they are: Older cheaper drugs used for many diseases and conditions before 1964 and are still used Drugs that are approved for one use, or one condition, but not for other conditions that it is effective and safe for. Drugs made by compounding pharmacies for diseases that the FDA has not approved a drug for, but there is research backing the drug and years of safe use. First, before we discuss the non-FDA approved drugs, I will discuss the safety/risks of FDA approved drugs, and why FDA approval doesn't mean a drug will do no harm or even that it is effective for the use it is approved for. A little background will help you understand the problem and the reason an FDA approval does not necessarily mean a drug is safe. Since 1964, a law was passed that established testing prior to a drug being approved by the FDA became mandatory. Since that time several drugs that survive FDA approval and are released but are later removed or banned after their FDA release when the public finds side effects that the FDA didn't discover in their trials. One such drug is Fen-Phen, Fenfluramine/Phentermine. This drug was released during my time practicing medicine and was withdrawn after one study claimed it caused heart valve disease…In the end the “one post approval study” that claimed that heart valves were affected by this drug that caused its bann was found to be false. The withdrawal of the drug followed one study by a single cardiologist from Kansas City had reviewed all of the cardiac valve echo tests and falsified the results to make Fen-Phen appear dangerous to heart valves, when in reality it wasn't. She lost her license, but the FDA never put Fen-Phen back on the market! The FDA hates to be wrong twice, so they never allowed this drug back on the market after its removal. Other mistakes made by the FDA include not allowing women in the studies to approve a drug before 2014 which ignores or misses all of the side effects or lack of effectiveness for a drug when taken by women. Despite all the expensive testing before the release of a drug by the FDA, many drugs not tested on women were later often found to have severe side effects only on women. A few examples follow: You might have heard of the FDA approved drug Ambien that causes many women to experience “night eating”, sleepwalking, and night terrors, while their male counterparts were not affected, so because they only tested men the drug was approved. In retrospect it should have been tested on women as well, and then either not passed through the FDA or should have had a black box warning for women. It takes years get action from the FDA, notifying doctors of these side effects. Women were not included in testing for any drugs except female hormones until 11 years ago, but no other drugs. Before 2014 all (non-hormonal) drugs that passed the FDA were not tested on women so the effect on women was unknown until it was tested on the public. The FDA left women out of drug-trials because it viewed women as “mini men”, or they didn't consider us important enough to test new drugs on…OR worse, they believed we were too complicated to easily test us because of pregnancy, menopause and other hormonal swings that normal healthy women have. In any case, we are now suffering their decisions, when a medication works one way for men and another way for women! Finally, we are tested when drugs are being evaluated for approval by the FDA. Professional women have achieved a level of authority in medicine and pharmacology (2025) and are weighing in on the inequity. Women in the medical profession and the public are pulling back the curtain on the side effects of FDA approved drugs that are experienced by women only! Slowly, study by study investigators are now publishing the side effects and problems for women with FDA approved drugs….yet these findings are not included in the warnings on most of these drugs, even now over 15 year after they became obvious to the doctors who treat women! Drugs that either don't work for women, or that have severe side effects include that were approved before 2014. All statin drugs for high cholesterol (Crestor, rosuvastatin, atorvastatin, etc.) cause women to have muscle breakdown and muscle pain. Synthroid (levothyroxine), doesn't cure the symptoms of hypothyroidism in 80% of women, but just makes the TSH lower, so it appears as if it is working! This leads doctors to tell women that their symptoms are all in their heads!! Wrong. It is the wrong medicine. Women have enzymes that differ from men that make it difficult for them to convert the inactive form (T4) into the active form (T3), so we can't convert Synthroid (all T4) into the active form. Synthroid, the FDA approved drug for hypothyroidism, shouldn't be given to most women. Women should be given the non-FDA approved drug Armour Thyroid or NP thyroid that have both T3 and T4 in them! Ambien Prednisone and other oral steroids We have reviewed the lack of testing on women before 2014, now we will discuss safe drugs that have been used for decades even before 1964 when the FDA required testing for FDA approval? Older, yet effective and inexpensive drugs have been tested by the public, some for almost 100 years that have saved thousands of lives, yet they are not given the FDA stamp of approval! In fact, the FDA tries to put these drugs out of circulation, replacing them with very expensive drugs that are new! Or they just shut them down, because they are not FDA approved. Young doctors are told not to use them by their medical schoolteachers who rarely have experienced these medications in private practice…. These doctors in training don't know the history of older safer, cheaper drugs, or even why the FDA tells them avoid them. They comply not knowing why, so you are left with no drug that works for you, or you pay 3-10 times the amount for a newer FDA version of the older drug which may even have more side effects. Some of these older very effective and cheap drugs are Penicillin, Nitroglycerine for chest pain, Morphine (pain), Phenobarbital (seizures), Codeine, Armour Thyroid, hormone injections including estradiol injections and testosterone, Thorazine for psychiatric use, (Pitocin) oxytocin for labor, lactation support and Autism Colchicine:Used to treat and prevent gout. Progesterone in oil (IM) Estradiol in oil (IM) B12 for injection Testosterone Cypionate for injection Compounded Estradiol in any form Compounded Testosterone for women These drugs have been used for so long that any safety risks or side effects have been found through the use of these drugs in the population. Yet the FDA won't grandfather them in and approve them based on their history! What do doctors do when the drug the FDA has approved a drug that doesn't work for a group of their patients (gender, race, blood type, etc.)? What happens when a doctor can't find a drug that is FDA approved needed to treat a condition she is faced with? Why do we as citizens, allow the government to have power over doctors who are already controlled by their state licensing boards as to what medications they? Lastly Why do taxpayers allow a government agency that they fund with tax dollars control their health by banning, or not approving drugs, or banning one drug so an outrageously expensive drug is put in its place? Compounded Medications/ Compounding Pharmacies: These drugs are made by mixing ingredients to meet individual patient needs and are not subject to premarket review for safety, effectiveness, or quality. However, they ARE subject to the success or failure for which they were prescribed. If a doctor prescribes a compounded drug that doesn't work, she is apt to be confronted by her patient who is not getting the expected results. Compounding pharmacies usually don't get paid by insurance, so patients are more invested in getting a drug that works and that is one of the big reasons that Compounded medicines are at least as good or better than big pharma or generic drugs. I absolutely could not successfully treat the thousands of women and men that I have without compounding pharmacies. They compound hormones/drugs that are safe and effective, mostly hormones that can't be patented because they occur in nature and won't ever be made by big pharma. More than that, big producers of drugs can't produce in mass quantities many doses of a certain hormone like compounding pharmacies do. Compounding pharmacies provide what people need and they continue to do so because patients prefer their dosing and quality. FDA approved Generic Drugs can be legally 25 % lower dose than what they say they are. That would be a big problem if my compounded pellets had that kind of variability. People might need pellets every 2months or every 5 months instead of every 4 months..it would be like guessing what you need ahead of time…..I believe dedicated compounding pharmacists are more accurate than any generic on the market. Compounding pharmacies: Unsung Heros Compounding pharmacies serve the public when big pharma fails and hasn't developed a safety net for production if they have a problem and the FDA shuts them down. That situation leaves patients who take their medications, without an alternative. Compounding pharmacies step into the breech when big pharma has a problem with a particular drug and stop making a drug (e.g. Lidocaine, B12 injectable, IV Fluids, to name a few shortages and no production that have occurred in the recent past). What if patients couldn't get the meds they need, and if there were no compounding pharmacies—Chaos and suffering and dying patients would closely follow! The FDA is Fickle and is not on your side! For years the FDA did not approve of Bioidentical estrogen and testosterone in any form, and just a few months ago all of a sudden, long after they scared women from taking the hormones they needed to improve their length of life and quality of life, they decided bioidentical hormones are better than the FDA approved hormones!!! That is a little too late. Some of us will never forget the stress lack of approval of compounded hormones caused for doctors and patients alike. Other doctors criticized us and now most of them aren't even in practice anymore. Maybe the FDA read my blog!!! Compounded hormones have been approved by the masses of women who have taken them under my signature! Compounded BI hormones are medications with a long track record and should not have to be tested with the bloated expense required of testing for the FDA. For Gynecological Disorders that don't have an FDA approved hormone drug because testosterone and estradiol have been used for so long that they don't need testing. If there was a significant problem with them their history of use of over 5-7 decades has proven the efficacy and safety of the female hormones for treatment and hormone replacement. For Psychiatric Disorders: Some patients need compounded ketamine products for conditions like severe depression, despite lacking FDA approval for these uses and potential risks, yet it has been used for this purpose for decades and was used for childbirth for almost a century, until epidurals and saddle blocks took their place. Testosterone for women still is not recognized as a female hormone even though women produce over twice as much Testosterone as Estradiol when they are in their fertile years. Replacement of T with bioidentical T pellets offers a treatment for dozens of symptoms women face after age 40, and it prevents the diseases of aging: osteoporosis, heart disease, sarcopenia, frailty, diabetes and more that have not been addressed by mainstream medicine and the FDA. Over a decade ago, the FDA turned down the approval of testosterone patch after over 3 years of positive research studies, the FDA said they didn't approve T for women is because the side effect of T for women, facial hair, was dangerous for women.…I cry B—–S—-! That is really men not wanting to share testosterone replacement with women. I say leave us alone and let women and their doctors determine what they need. It is proven that only 5% of all professionals in any profession are not trustworthy, so give doctors their due and trust that we are looking for answers to our patients' problems that you don't even know about! The FDA is paid for by us…everyone in this country. I say hands off! Speed up the approval process or forget it for older drugs and BI hormones! ~
This lesson overlaps two chapters (Job 29:21–30:19). Was the change so abrupt that a division was inserted?
Damon Bruce Plus: Warriors, 49ers, Giants, A’s Bay Area Sports Talk
Forget where ya hope to go, just try and get there. One. Game. At. A. Time. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Trust can be a Fickle lover… Who do you trust and why do you trust them? Did they earn it? Prove it? Or do they start at 100% trust and go down from there? Oh, you capricious thing called trust. But the bigger question is “Do you trust you?” and if so, how deep is that trust? Do you trust your awareness? Your body? Your business? Your being? Many can only trust what they have judged as right, which isn't really trust at all if you look at it. I invite you to explore this with me in the Curious Universe with my unique guest Gabor Gürtler, as you discover how deep is your trust?At 27, G (Gabor) lost everything — his health, business, relationship, and financial stability. What seemed like the end became the beginning of The Process: a journey of being.. you.Today, his work reaches hundreds of thousands, reminding people that they can choose different — and create a life they'd gladly wake up into.For more with Gabor please explore here: folyamat.comyoutube.com/@folyamathttps://www.instagram.com/folyamatcomtiktok.com/@folyamat
NEW EPISODES ARE BACK! The finish line isn't always what you dream it will be. It can be life-changing or it can be a lonely road. Are you good enough?Are you fast enough?What are you trying to prove out there? Does a finish line really define you or your life? Eric Recker experienced too many of those fickle finish lines in his life. He wanted more. He needed more. A reel showed up in Eric's social media feed - 29029 Everesting Do you have what it takes? - and a journey of self-discovery and purpose ensued. Subscribe to the 29029 Podcast for more inspiring content.Learn more about 29029 Events and our community HERE.
Badgers Camp is heating up and some familiar names are standing out! In today's episode of the podcast, Alex and KJ lean into the veterans returning for Fickle's UW squad and how they can play simple and to their strengths. What are you predicting will happen? Running through the Top 25 pre-season and more - Welcome to the IKE Badgers Podcast! Subscribing, leaving a five-star review on the Apple Podcasts, and telling a friend is the #1 way to help the show.Follow IKE Badgers on Twitter for Live-Tweeting of Badgers Football @IKE_BadgersFan of the music? Stream "IKE Music" on SpotifyLearn more about the #1 podcast network in the state of Wisconsin by visiting ikepodcastnetwork.com@welcometoike
Gabrielle Drolet had always dreamed of being a writer. But when disability closed down most of her opportunities, a strange career began By Gabrielle Drolet. Read by Kate Handford. Help support our independent journalism at theguardian.com/longreadpod
Hexcloak justiciar Caoimhe Wake and her two ad hoc assistant investigators, Antistrophe Landrace and Brontë Adelvys, have their work cut out for them. First and foremost, there's the matter of these strange, flaming creatures attacking a traveling Lobble and his stagecoach full of supplies. And then there's there's the matter of Burzin, the small desert township on the horizon. After generations of simplicity and stability, the town has faced a sudden wave of inexplicable destruction as a phenomenon that can only be described as “invisible fire” has razed much of the town to ash. Will Caoimhe, Antistrophe, and Brontë find who—or what—is behind the blaze? Or will what remains of Burzin soon be burned away? This week on Perpetua: The Flames of Burzin Pt. 2 Perpetua Guide [In Progress v.02] NPCs & Monsters [PNMS] Flarie [NMFLR] Typical Traits: Curious, Fickle, Scornful, Superior Stats: DEX 8, INS 10, MIG 6, WLP 8 Attacks: Flame Dart Special Abilities: Flying, Crisis: Wildfire In-Game Description: A devious flying flame, vaguely int he shape of a fairy. Flaries are cute, but they're also dangerous, especially early on! They're ranged attackers who hover just out of melee reach, so you'll need to either hit crit them or get them down to half health with ranged or magic attacks, or hit their elemental weakness. And remember, Perpetua doesn't have water magic for some reason, and Fire often Melts Ice! Any guesses on what that leaves as a natural vulnerability? That's right: EARTH. Toss some dirt on these little jerks and you'll bring ‘em down to ground level. Starter Tip: Get ready to heal once you knock them into crisis! Their Wildfire move is devastating! Embear [NMEMB] Typical Traits: Pround, Hungry, Scorching, Territorial Stats: DEX 8, INS 8, MIG 10, WLP 6 Attacks: Flame Claw Special Abilities: Burn Back (Reaction) In-Game Description: A large, ursine figure of fire looking for something to eat. These guys are the brawn to the Flaries'... well, not quite brains, but fla(i)r, I guess? At the start of the game, they really pack a wallop, so try to keep your weaker characters away from their Flame Claw strikes. I wonder what type of bear they're supposed to be? Do any bears really live in the dessert??? Starter Tip: At first blush, their Burn Back reaction attack seems totally broken. But remember, it only hits melee attackers! Aisling Revanj (she/her) [NMAR] Traits: Ambitious, Mean Spirited, Envious, Loyal Stats: ??? Attacks: ??? Spells: ??? In-Game Descriptions: Fiery Hexcloak who oversees Burzin and the surrounding region. When I first saw concept art of her during previous, I thought she'd be one of my favorite characters, but it turns out that she's an ABSOLUTE B**! She's so superior and “holier-than-thou,” if that's the right phrase. And it's not like she solves ANYTHING, she's just always getting int he way. I cannot WAIT to fight her later on in the game. Starter Tip: You can basically button through all of her dialog, she doesn't say anything important IMO! Hosted by Austin Walker (austinwalker.bsky.social) Featuring Janine Hawkins (@bleatingheart), Sylvi Bullet (@sylvibullet), and Keith J Carberry (@keithjcarberry) Produced by Ali Acampora Music by Jack de Quidt (available on bandcamp) Cover Art by Ben McEntee (https://linktr.ee/benmce.art) With thanks to Amelia Renee, Arthur B., Aster Maragos, Bill Kaszubski, Cassie Jones, Clark, DB, Daniel Laloggia, Diana Crowley, Edwin Adelsberger, Emrys, Greg Cobb, Ian O'Dea, Ian Urbina, Irina A., Jack Shirai, Jake Strang, Katie Diekhaus, Ken George, Konisforce, Kristina Harris Esq, L Tantivy, Lawson Coleman, Mark Conner, Mike & Ruby, Muna A, Nat Knight, Olive Perry, Quinn Pollock, Robert Lasica, Shawn Drape, Shawn Hall, Summer Rose, TeganEden, Thomas Whitney, Voi, chocoube, deepFlaw, fen, & weakmint This episode was made with support from listeners like you! To support us, you can go to friendsatthetable.cash.
This week, the gals question everything they've ever learned from Peter Thomas. Topics include some crunchy crime scenes, plaid shirt probability, and a bunch of blood spatter banter. Get your hands on some Evidence Wines, fingerprint your coworkers, and tune in for Fickle Forensics. For a full list of show sponsors, visit https://wineandcrimepodcast.com/sponsors. To advertise on Wine & Crime, please email ad-sales@libsyn.com or go to advertising.libsyn.com/winecrime.
President Xi Jinping's style of negotiating is staid, distanced, a quiet projection of power. President Donald Trump's is not. That dynamic is complicating their gargantuan standoff. Spain ends up with more and more remains of migrants who die on their journeys—and its morgues cannot keep up (10:29). And in an age of video games pinball is not only surviving, it's flipping thriving (18:11).Get a world of insights by subscribing to Economist Podcasts+. For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account. Hosted on Acast. See acast.com/privacy for more information.
President Xi Jinping's style of negotiating is staid, distanced, a quiet projection of power. President Donald Trump's is not. That dynamic is complicating their gargantuan standoff. Spain ends up with more and more remains of migrants who die on their journeys—and its morgues cannot keep up (10:29). And in an age of video games pinball is not only surviving, it's flipping thriving (18:11).Get a world of insights by subscribing to Economist Podcasts+. For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.
As we continue to follow the missions of Paul and Barnabas, Fr. Mike highlights the fickle nature of humanity and the futility of striving for the praise of men. He also encourages us to remain courageous in the tribulations we face, finding strength in other believers, and running toward the eternal and imperishable goal of salvation. Today's readings are Acts 14, 1 Corinthians 9-10, and Proverbs 28:7-9. For the complete reading plan, visit ascensionpress.com/bibleinayear. Please note: The Bible contains adult themes that may not be suitable for children - parental discretion is advised.