Podcasts about confirmatory

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Best podcasts about confirmatory

Latest podcast episodes about confirmatory

Logopraxis
The only safeguard we have is the practise of the Word (3 mins)

Logopraxis

Play Episode Listen Later Jun 7, 2024


The spiritual states in us need to confirm what they have learnt from 'others' Doctrine of Faith 1. Faith is an internal acknowledgment of truth.By faith at the present day is understood nothing more than the mental presumption that a thing is so, because it is taught by the Church, and because it is not evident to the understanding. For it is said: Believe, and do not doubt. If you answer, I do not comprehend it, you are told that this is the reason why it must be believed. The faith of the present day, therefore, is a faith in what is not known, and may be called a blind faith; and as it is the dictate of one person passed on to another, it is an historical faith. That this is not spiritual faith will be seen in what follows. Arcana Coelestia  6945(3)...And as there was no such force before the Lord's coming, but only after His coming, when He had made the Human in Himself Divine, therefore they could not be taken out of the lower earth, where they were being infested by falsities, and be taken up into heaven, until after the Lord's resurrection (n. 6914). From this then it is that it is said that they would not believe, thus neither would receive what the law Divine, that is, the truth Divine says, unless they saw that it is so, thus unless they saw signs. AC 2831. Behind, caught in a thicket. That this signifies entangled in natural knowledge, is evident from the signification of being “caught,” as here being entangled; and from the signification of a “thicket” or “tangle” as being memory-knowledge-explained in what follows. That the spiritual are held entangled in natural knowledge in regard to the truths of faith, is as follows. The spiritual have not perception of good and truth, as the celestial have, but instead of it conscience formed from the goods and truths of faith which they have imbibed from infancy from their parents and masters, and afterwards from the doctrine of faith into which they were born. They who have no perception of good and truth have to be confirmed by knowledges. Everyone forms for himself some idea respecting the things he has learned, and also respecting the goods and truths of faith; for without an idea, nothing remains in the memory otherwise than as an empty thing. Confirmatory things are added thereto, and fill up the idea of the thing, from other knowledges, even from memory-knowledges. The confirmation of the idea itself by many things causes not only that it sticks in the memory, so that it can be called forth into the thought, but also that faith can be insinuated into it. AC 6240...What the rational is shall be briefly told. The intellectual of the internal man is called “rational,” but the intellectual of the external man is called “natural;” thus the rational is internal, and the natural is external; and they are perfectly distinct from each other. But a truly rational man is no other than he who is called a celestial man, and who has perception of good, and from good perception of truth; whereas he who has not this perception, but only the knowledge that a thing is true because he is so instructed, and from this has conscience, is not truly a rational man, but is an interior natural man. Such are they who are of the Lord's spiritual church. They differ from the celestial as the light of the moon differs from the light of the sun; and therefore the Lord appears to the spiritual as a moon, but to the celestial as a sun (see n. 1521, 1529-1531, 4060, 4696). [2] Many in the world suppose that a rational man is one who can reason acutely about many things, and so join his reasonings together that his conclusions may appear like truth; but this is found in the very worst of men, who are able to reason skillfully and persuade that evils are goods, and that falsities are truths; and the reverse. But he who reflects can see that this is vicious phantasy, and not what is rational. The rational consists in inwardly seeing and perceiving that good is good,

M&A Science
How to Close M&A Deals in 30 Days

M&A Science

Play Episode Listen Later May 27, 2024 54:16


Jeremy Segal, Executive Vice President Corporate Development at Progress (NASDAQ: PRGS) When it comes to M&A, time is of the essence. As a buyer, it's best to identify whether to pursue the deal or not as soon as possible, to avoid wasting money and time. Also, if the seller is a good target company, procrastinating could lead to more competition.  In this episode of the M&A Science Podcast, Jeremy Segal, Executive Vice President Corporate Development at Progress, shares their strategy on how to close deals in 30 days. Things you will learn: Initial conversations with the target company Price negotiations Preliminary due diligence list Deal specific adjustments Confirmatory due diligence  This episode is sponsored by the DealRoom. Ready to take your M&A to the next level with software made to manage each stage of the deal process? See how DealRoom can facilitate your next deal at https://dealroom.net    

Quantitude
S5E08 Confirmatory Composite Analysis: Enter the Hexagon

Quantitude

Play Episode Listen Later Nov 14, 2023 48:58


In today's episode, Greg and Patrick dig into Confirmatory Composite Analysis, a very clever way to get formative factors and their causal indicators into the traditional structural equation modeling framework, along with any other latent factors and their effect indicators that might already be in the model. Along the way they also mention full-contact Wordle, being grounded, spelling bees, state capitals, definitions of leadership, a many ways, rabbit or duck, set of steak knives, canonical correlation vs. Homer Simpson, secret sauce, Quantitude Word of the Day, Who's a good boy?, the man behind the curtain, Penn and Tellering, a new symbol, Beavis, and car stereo wiring diagrams.Stay in contact with Quantitude! Twitter: @quantitudepod Web page: quantitudepod.org Merch: redbubble.com

PeerVoice Internal Medicine Audio
Jacqueline Turner, MSc - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Internal Medicine Audio

Play Episode Listen Later Sep 5, 2023 16:12


Jacqueline Turner, MSc - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Internal Medicine Video
Jacqueline Turner, MSc - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Internal Medicine Video

Play Episode Listen Later Sep 5, 2023 16:16


Jacqueline Turner, MSc - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Brain & Behaviour Video
Jacqueline Turner, MSc - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Brain & Behaviour Video

Play Episode Listen Later Sep 5, 2023 16:16


Jacqueline Turner, MSc - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Brain & Behaviour Audio
Jacqueline Turner, MSc - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Brain & Behaviour Audio

Play Episode Listen Later Sep 5, 2023 16:12


Jacqueline Turner, MSc - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

Within & Between
S4E8: LIVE EPISODE! So you measured something twice, now what?

Within & Between

Play Episode Listen Later Jul 5, 2023 48:07


Measuring change is our first ever LIVE EPISODE! Recorded at the Association for Psychological Science conference with a live conference audience! Over here in the developmental sciences, we are often trying to measure or predict how much people grow and change over time. To do that, we'll sometimes measure a skill or ability twice (for kids, maybe that's once near the beginning of the school year and once at the end of the school year). In this episode, Jess and Sara talk about options for statistically modeling and predicting change between two timepoints. We talk about two basic models: the simple difference scores and residualized gain scores, explain why we can't just measure people at post test, and conclude that the question is important in making your decision. Have a listen as we get to take some related questions from the audience.  Things we mentioned:  If you are working in the latent space and have a measurement model at each time point, you may need to establish measurement invariance across time. To do so, you can follow steps in Brown (2015; pp. 259–265).  Brown, T. A. (2015). Confirmatory factor analysis for applied research (2nd ed.). Guilford Publications. Connect with the podcast on twitter @within_between, or email us letters about developmental science at withinandbetweenpod@gmail.com. More episodes and podcast information at WithinandBetweenPod.com. Follow Dr. Hart on twitter @Saraannhart Follow Dr. Logan on twitter @Jarlogan. Our theme music was composed by Jason Flowers. Our logo was created by Nathan Archer. Recorded May 27th, 2023.

M&A Science
Best Practices When Selling a Business

M&A Science

Play Episode Listen Later May 22, 2023 50:08


Jeff Wald, Co-founder of Bento Engine This episode is sponsored by the M&A Science Academy, DealRoom, and FirmRoom.  To join our growing online community of M&A practitioners, visit https://www.mascience.com/academy. Don't forget to use code “podcast” at checkout.  Ready to take your M&A to the next level with software made to manage each stage of the deal process? See how DealRoom can facilitate your next deal at https://www.dealroom.net   FirmRoom provides 80% cost savings over VDRs that bill by page and delivers a far better user experience to boot. Sign up in under 2 minutes by going to https://www.firmroom.com  Episode Timestamps 00:00 Intro 03:44 Best practices during exits 04:41 Thinking about an exit 09:54 Engaging with investors 14:13 The path to being acquired 18:24 Tips for Outreach 19:49 First conversation 25:11 Key people when executing deals 29:00 Negotiating Law firm prices 30:16 Negotiating LOI 34:37 Confirmatory due diligence 37:06 Communicating with employees 39:13 Announce day 44:55 Integration 47:46 Craziest thing in M&A  

The Peter Attia Drive
#247 ‒ Preventing cardiovascular disease: the latest in diagnostic imaging, blood pressure, metabolic health, and more | Ethan Weiss, M.D.

The Peter Attia Drive

Play Episode Listen Later Mar 20, 2023 132:54


View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Ethan Weiss is a preventative cardiologist at UCSF, an entrepreneur-in-residence at Third Rock Ventures, where he is working on a project related to cardiometabolic disease, and a previous guest on The Drive. In this episode, Ethan compares and contrasts the diagnostic imaging tools, CAC (coronary artery calcium score) and CTA (CT angiography), used to image plaque—including the latest in CTA software—and how these tools inform our understanding of ASCVD risk and guide clinical decision-making. Ethan discusses the types of plaque that cause events and the data that make a case for optimal medical therapy over stenting outside of particular cases. He explains why high blood pressure is problematic and walks through the data from clinical trials testing aggressive treatment. He talks about the best way to actually measure blood pressure, why we shouldn't simply accept that blood pressure rises with age, and how he uses different pharmaceutical agents to treat hypertension. Additionally, Ethan explains our current, but limited, understanding of the role of metabolic health in ASCVD. He discusses the impact of fat storage capacity and the location of fat storage and explains how and why there is still a residual risk, even in people who have seemingly normal lipids, don't smoke, and have normal blood pressure. We discuss: Ethan's entrepreneurial work in the cardiometabolic disease space [4:30]; Calcium scans (CAC scores) and CT angiography (CTA), and how it informs us about ASCVD risk [6:00]; Peter's historical CAC scores, CTA results, and how one can be misled [10:45]; How Peter's CTA results prompted him to lower his apoB [14:45]; Calcium scans vs. CT angiogram (CTA) [21:15]; How Ethan makes clinical decisions based on CTA results and plaque burden, and the importance of starting treatment early to prevent ASCVD [28:15]; Improved methods of CTA to grade plaque lesions and how it's shaped medical decisions such as stenting [33:45]; Why Ethan favors optimal medical therapy over stenting outside of particular situations [41:45]; The need for FFR CTA, and the potential for medical therapy to eliminate ASCVD [54:00]; The fat attenuation index (FAI) and other ways to measure inflammation in a plaque [57:30]; Statins and exercise may increase the risk of calcification, but what does this mean for risk? [59:45]; The root cause of statin hesitation despite evidence that statins are a profoundly important intervention [1:05:30]; Importance of keeping blood pressure in check, defining what's normal, and whether we should just accept higher blood pressure with age [1:10:45]; Blood pressure variability, how to best measure it, and data suggesting the enormous impact of keeping blood pressure down [1:21:00]; Drugs for treating high blood pressure recommended by the ALLHAT trial [1:35:15]; What the SPRINT trial says about the aggressive treatment of hypertension, and the risks of such treatment [1:38:15]; Confirmatory results in the STEP trial for blood pressure, and how Ethan uses the various pharmacological agents to lower blood pressure in patients [1:43:15]; The role metabolic health in ASCVD: what we do and don't know [1:51:00]; The impact of fat storage capacity and the location of fat storage on metabolic health and coronary artery disease [1:56:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

JALM Talk Podcast
Deceptively Simple: Can Urine Samples from CLIA-Waived Urine Drug Screen Devices Be Reused for Confirmatory Testing?

JALM Talk Podcast

Play Episode Listen Later Mar 3, 2023 9:27


PeerVoice Clinical Pharmacology Audio
Graeme C Black, OBE, DPhil, FRCOphth, FMedSci - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Clinical Pharmacology Audio

Play Episode Listen Later Dec 14, 2022 15:28


Graeme C Black, OBE, DPhil, FRCOphth, FMedSci - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Internal Medicine Audio
Graeme C Black, OBE, DPhil, FRCOphth, FMedSci - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Internal Medicine Audio

Play Episode Listen Later Dec 14, 2022 15:28


Graeme C Black, OBE, DPhil, FRCOphth, FMedSci - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Clinical Pharmacology Video
Graeme C Black, OBE, DPhil, FRCOphth, FMedSci - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Clinical Pharmacology Video

Play Episode Listen Later Dec 14, 2022 16:06


Graeme C Black, OBE, DPhil, FRCOphth, FMedSci - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Brain & Behaviour Audio
Graeme C Black, OBE, DPhil, FRCOphth, FMedSci - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Brain & Behaviour Audio

Play Episode Listen Later Dec 14, 2022 15:28


Graeme C Black, OBE, DPhil, FRCOphth, FMedSci - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Brain & Behaviour Video
Graeme C Black, OBE, DPhil, FRCOphth, FMedSci - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Brain & Behaviour Video

Play Episode Listen Later Dec 14, 2022 16:06


Graeme C Black, OBE, DPhil, FRCOphth, FMedSci - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Internal Medicine Video
Graeme C Black, OBE, DPhil, FRCOphth, FMedSci - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Internal Medicine Video

Play Episode Listen Later Dec 14, 2022 16:06


Graeme C Black, OBE, DPhil, FRCOphth, FMedSci - Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

The Modern Therapist's Survival Guide with Curt Widhalm and Katie Vernoy
Navigating the Social Media Self-Diagnosis Trend

The Modern Therapist's Survival Guide with Curt Widhalm and Katie Vernoy

Play Episode Listen Later Dec 12, 2022 32:23


Navigating the Social Media Self-Diagnosis Trend Curt and Katie chat about the TikTok Mental Health and the self-diagnosis trend. We dig into what diagnosis is (and what is actually useful about diagnosis). We also explore the concerns with social media self-diagnosis as well as how we can support our clients with getting accurate assessment and treatment.   Transcripts for this episode will be available at mtsgpodcast.com! In this podcast episode we talk about self-diagnosis and the impact of social media We have both heard about TikTok diagnoses in our practices and wanted to talk about how therapists might navigate this new trend.   What is the TikTok trend of self-diagnosis? Lots of influencers on social media are sharing content Unvetted content creators Some good information mixed in with very vague information that can be confusing What is diagnosis? “The way I see diagnosis is that it's a construct… It's labeling folks that seem to fall together with similar symptoms. And the medical model says, that's a real thing. And then we can do treatments or prescribe medication for it... And so, to me, some of the self-diagnosis stuff is almost colluding with this medical model that's saying, if you have a couple of these things over here, and a couple of those things over here, then you have this label, this label is a real thing. And that blows my mind, because I think a lot of folks in the self-diagnosis realm are trying to kind of push up against the establishment, but they're lending credence to this idea that diagnosis is a real, concrete thing versus a tool to help with treatment planning, and to understanding us better.” – Katie Vernoy, LMFT Rosenhan experiment (experiment showing that malingering patients will probably be misdiagnosed) Constructs of things that typically fall together Effective for treatment planning and getting this treatment covered by insurance Identity versus something to heal What are concerns with social media self-diagnosis? “The point of having a professional be able to properly evaluate is looking through that more nuanced clinical eye in order to look at where the threshold is that actually meets diagnostic [criteria] versus actually just having some characteristics in common with [the diagnosis]. Somebody can be nervous, does not mean that they have anxiety… What is pathologizing normal feelings?” – Curt Widhalm, LMFT Focusing in on small elements and then having that frame their full life experience Seeking only confirmatory diagnosis versus allowing for differential diagnosis Clinicians who are not doing full assessments to support clients who have self-diagnosed Clients who do not need treatment taking slots from those who do need assessment and treatment Lack of nuance in the social media content that doesn't include information on differential diagnosis Inaccurate treatments based on inaccurate self-diagnosis Malingering and factitious disorder risk Pathologizing normal feelings Being inundated with so much information Confirmatory bias How to support clients who have sought diagnostic information on social media and google? “What started the whole thing… clinicians under diagnosing, undervaluing client feedback, not asking all the right questions. And so, folks are feeling dissatisfied with what we're doing and heading to the interweb to understand better what it is that's going on.” – Katie Vernoy, LMFT Therapists need to listen to their clients, so they don't feel the need to go elsewhere for information Identify what is resonating for clients and explore what it means to them Educate clients about differential diagnosis Walk through their research (to listen and to help vet sources) Take your client seriously and support them in getting the help they need   Our Generous Sponsor for this episode of the Modern Therapist's Survival Guide: Thrizer Thrizer is a new modern billing platform for therapists that was built on the belief that therapy should be accessible AND clinicians should earn what they are worth. Their platform automatically gets clients reimbursed by their insurance after every session. Just by billing your clients through Thrizer, you can potentially save them hundreds every month, with no extra work on your end. Every time you bill a client through Thrizer, an insurance claim is automatically generated and sent directly to the client's insurance. From there, Thrizer provides concierge support to ensure clients get their reimbursement quickly, directly into their bank account. By eliminating reimbursement by check, confusion around benefits, and obscurity with reimbursement status, they allow your clients to focus on what actually matters rather than worrying about their money. It is very quick to get set up and it works great in completement with EHR systems. Their team is super helpful and responsive, and the founder is actually a long-time therapy client who grew frustrated with his reimbursement times The best part is you don't need to give up your rate. They charge a standard 3% payment processing fee! Thrizer lets you become more accessible while remaining in complete control of your practice. A better experience for your clients during therapy means higher retention. Money won't be the reason they quit on therapy. Sign up using bit.ly/moderntherapists if you want to test Thrizer completely risk free! Sign up for Thrizer with code 'moderntherapists' for 1 month of no credit card fees or payment processing fees! That's right - you will get one month of no payment processing fees, meaning you earn 100% of your cash rate during that time. Resources for Modern Therapists mentioned in this Podcast Episode: We've pulled together resources mentioned in this episode and put together some handy-dandy links. Please note that some of the links below may be affiliate links, so if you purchase after clicking below, we may get a little bit of cash in our pockets. We thank you in advance! The Rosenhan experiment Articles: TikTok Mental Illness Diagnosis Deconstructing TikTok Videos on Mental Health: Cross-sectional, Descriptive Content Analysis Young People Are Using TikTok to Diagnose Themselves With Serious Mental Health Disorders. What's Behind This Trend? TikTok and the Dangers of Self-Diagnosing Mental Health Disorders Why "TikTok Diagnoses" Are on the Rise Why the nature of TikTok could exacerbate a worrisome social media trend Young Women Are Self-Diagnosing Personality Disorders, Thanks To TikTok   Relevant Episodes of MTSG Podcast: What's New in the DSM-5-TR: An interview with Dr. Michael B. First Portrayals of Mental Health and Therapy in the Media: An interview with Danah Davis Williams, LMFT Should Therapists Correct Their Clients? It's Not a Chemical Imbalance: An interview with Dr. Kristen Syme Is Therapy an Opiate of the Masses? Speaking Up for Mental Health Awareness: An interview with Metta World Peace   Who we are: Curt Widhalm, LMFT Curt Widhalm is in private practice in the Los Angeles area. He is the cofounder of the Therapy Reimagined conference, an Adjunct Professor at Pepperdine University and CSUN, a former Subject Matter Expert for the California Board of Behavioral Sciences, former CFO of the California Association of Marriage and Family Therapists, and a loving husband and father. He is 1/2 great person, 1/2 provocateur, and 1/2 geek, in that order. He dabbles in the dark art of making "dad jokes" and usually has a half-empty cup of coffee somewhere nearby. Learn more at: www.curtwidhalm.com Katie Vernoy, LMFT Katie Vernoy is a Licensed Marriage and Family Therapist, coach, and consultant supporting leaders, visionaries, executives, and helping professionals to create sustainable careers. Katie, with Curt, has developed workshops and a conference, Therapy Reimagined, to support therapists navigating through the modern challenges of this profession. Katie is also a former President of the California Association of Marriage and Family Therapists. In her spare time, Katie is secretly siphoning off Curt's youthful energy, so that she can take over the world. Learn more at: www.katievernoy.com A Quick Note: Our opinions are our own. We are only speaking for ourselves – except when we speak for each other, or over each other. We're working on it. Our guests are also only speaking for themselves and have their own opinions. We aren't trying to take their voice, and no one speaks for us either. Mostly because they don't want to, but hey. Stay in Touch with Curt, Katie, and the whole Therapy Reimagined #TherapyMovement: Patreon Buy Me A Coffee Podcast Homepage Therapy Reimagined Homepage Facebook Twitter Instagram YouTube   Consultation services with Curt Widhalm or Katie Vernoy: The Fifty-Minute Hour Connect with the Modern Therapist Community: Our Facebook Group – The Modern Therapists Group Modern Therapist's Survival Guide Creative Credits: Voice Over by DW McCann https://www.facebook.com/McCannDW/ Music by Crystal Grooms Mangano https://groomsymusic.com/

Pharma Intelligence Podcasts
Drug Fix: BIO CEO Departs, Makena Withdrawal Hearing Nears, New Confirmatory Evidence Sources

Pharma Intelligence Podcasts

Play Episode Listen Later Oct 14, 2022 43:31


Pink Sheet reporters and editors discuss Michelle McMurry-Heath's surprising departure as head of a top biotech industry trade association, preview the FDA hearing to withdraw the preterm birth prevention drug Makena, and consider Amylyx's Relyvrio seemingly opening a wider path to gather confirmatory evidence for approval.

THUNK - Audio Interface
228. The Intelligence Trap & Evidence-Based Wisdom

THUNK - Audio Interface

Play Episode Listen Later Sep 3, 2022 10:58


https://youtu.be/1K23sO-G0uE We often look to intelligent individuals to provide us with insight & guidance, but if you ask science writer David Robson, intelligence isn't just the wrong barometer for good decision-making, it might make for *worse* decisions! -Links for the Curious- The Intelligence Trap, by David Robson - https://www.betterworldbooks.com/product/detail/The-Intelligence-Trap---Why-Smart-People-Make-Dumb-Mistakes-9780393651423 The Evidence-Based Wisdom Blog - https://evidencebasedwisdom.com/ Decision-Making Competence: More Than Intelligence? (Bruin et al, 2020) - https://journals.sagepub.com/doi/pdf/10.1177/0963721420901592 A Route to Well-being: Intelligence vs. Wise Reasoning (Grossman et al, 2014) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594053/pdf/nihms422604.pdf Confirmatory factor analysis of the Sternberg Triarchic Abilities Test in three international samples: An empirical test of the triarchic theory of intelligence (Sternberg et al, 2001) - https://psycnet.apa.org/record/2001-14900-001 Insensitivity to future consequences following damage to human prefrontal cortex (Bechara, Damasio et al,, 1994) - https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.407.9471&rep=rep1&type=pdf The Iowa Gambling Task and the somatic marker hypothesis: some questions and answers (Bechara, Damasio et al,, 2005) - https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.137.6124&rep=rep1&type=pdf Deciding Advantageously Before Knowing the Advantageous Strategy (Bechara, Damasio et al, 1997) - https://www.cs.utexas.edu/~dana/Damasio2.pdf Neil deGrasse Tyson Has a Critically Important Message for Americans - https://futurism.com/watch-neil-degrasse-tyson-has-a-critically-important-message-for-americans Bill Gates: Japan can play big role in fight against infectious diseases | NHK WORLD-JAPAN News - https://www3.nhk.or.jp/nhkworld/en/news/20220820_02/ Bill Gates reveals his involvement in pushing through climate bill in interview with Bloomberg | Fox News - https://www.foxnews.com/media/bill-gates-reveals-involvement-pushing-through-climate-bill-interview-bloomberg IAmA 74-time Jeopardy! champion, Ken Jennings. I will not be answering in the form of a question. - https://www.reddit.com/r/IAmA/comments/fwpzj/iama_74time_jeopardy_champion_ken_jennings_i_will/ Bill Gates, Big Pharma and entrenching the vaccine apartheid - The Mail & Guardian - https://mg.co.za/coronavirus-essentials/2021-01-30-bill-gates-big-pharma-and-entrenching-the-vaccine-apartheid/ Why Socialism? (Einstein, 1949) - https://monthlyreview.org/2009/05/01/why-socialism/ Cocktail party ideas (Dan Luu) - https://danluu.com/cocktail-ideas/

Criminal Behaviorology
The McMartin Sexual Abuse Trial: Operant Seeing and the Dangers of Expert Opinion

Criminal Behaviorology

Play Episode Listen Later Jul 22, 2022 60:43


The video of this entire interview can be viewed here: https://youtu.be/xA3ZDZ8COBM Joseph Wyatt, Ph.D., is a retired forensic psychologist, and previous guest on Criminal Behaviorology. In 2002 he took an interest in the infamous McMartin Preschool trial, which took place in California. If you have not heard of this case, take some time to look up the story. It is simply the most shocking case of false accusation I have encountered. Joe takes a critical, and behavior analytic, viewpoint regarding the expert opinion of an archeologist who claimed to have discovered evidence of sinister tunnels built under the preschool buildings. These tunnels would seem to confirm the allegations of secret sexual abuse and ritualistic torture. But is there an alternative conclusion - one with a behavior analytic explanation? (Podcast listeners - skip to 10:12 unless you enjoy Joe and I conversing on audio quality) Show Highlights: - A respected preschool center is accused of crimes so shocking it made news the world over. - The use of anatomically detailed dolls to facilitate interviews with children. The misapplication of these methods, and the belief that children could not make up such explicit stories, led to the unjust prosecution in the McMartin case. - How children could be influenced by the interviewing techniques used in the case. - The parents of children involved in the case, in a very emotional state, asked for an archeological analysis to provide evidence of secret tunnels allegedly put in place to commit unspeakable crimes beneath the building. Ground penetrating radar, and a detailed report followed that supported the existence of underground tunnels. - Skinner's concept of “Operant Seeing.” Is this an explanation for why an expert archeologist's flawed conclusions when the totality of the evidence clearly indicates an innocent explanation? Confirmatory bias - the pursuing of conclusions before the facts. - The legacy of the McMartin trial. How could so many be so wrong about such a serious criminal case? The real victims of McMartin case. McMartin Sexual Abuse Trial and the 2002 article by Joseph Wyatt: https://en.wikipedia.org/wiki/McMartin_preschool_trial https://mds.marshall.edu/cgi/viewcontent.cgi?article=1006&context=psychology_faculty The film Indictment (starring James Woods): https://youtu.be/uMijKJg-7rk https://www.imdb.com/title/tt0113421/?ref_=ext_shr_lnk Joseph Wyatt on Criminal Behaviorology - Interview with the Forensic Psychologist (2019): https://anchor.fm/criminalbehaviorology/episodes/Interview-with-the-Forensic-Psychologist--Dr--W--Joseph-Wyatt-discusses-his-long-career-as-it-is-detailed-in-his-book---The-Breaking-Point-Killing-And-Other-True-Cases-of-Murder-and-Malice-e3aq6g Look up CrimBehav on Facebook: facebook.com/CrimBehav. Criminal Behaviorology on Blogger.  CB Podcast Sites: https://criminalbehaviorology.podomatic.com https://anchor.fm/criminalbehaviorology https://itunes.apple.com/us/podcast/criminal-behaviorology/id1441879795?mt=2&uo=4 
https://www.google.com/podcasts?feed=aHR0cHM6Ly9hbmNob3IuZm0vcy83MzY4OWFjL3BvZGNhc3QvcnNz
https://open.spotify.com/show/5VM7Sjv762u7nb91YWGczZ 
https://www.breaker.audio/criminal-behaviorology 
https://overcast.fm/itunes1441879795/criminal-behaviorology 
https://pca.st/Q38w 
https://radiopublic.com/criminal-behaviorology-GEv2AZ 
https://www.stitcher.com/podcast/anchor-podcasts/criminal-behaviorology https://www.youtube.com/channel/UCKSVoZOBwCG28xMnuPq_Gtw On Locals Social Media: https://criminalbehaviorology.locals.com/?showPosts=1 https://criminalbehaviorology.locals.com Please write a review on any of our podcast sites listed above. Questions, comments, and requests for transcripts to: 
 criminalbehaviorology@gmail.com Thank you for listening. --- Support this podcast: https://anchor.fm/criminalbehaviorology/support

M&A Science
156. How to Run an Integration Led Confirmatory Diligence Process

M&A Science

Play Episode Listen Later May 2, 2022 45:30


Jim Buckley, Vice President, Mergers and Acquisitions Integration at VMware (NYSE: VMW) It doesn't matter if you buy the best company in the world, if integration is not done properly, value will be lost. And while there are a handful of companies embracing the value of integration and bringing the integration team in during the diligence process, some take it even further.  In this episode of the M&A Science Podcast, Jim Buckley, Vice President, Mergers and Acquisitions Integration at VMware, talks about how to run an integration-led confirmatory diligence process.  Things you will learn in this episode: -The difference between a corporate development and integration team -Why you should involve the integration team pre LOI -How integration leaders draft diligence questions -The do's and don'ts of integration To join our network of M&A practitioners and sign up for our newsletter, go to mascience.com.

PeerVoice Clinical Pharmacology Audio
Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Clinical Pharmacology Audio

Play Episode Listen Later Mar 29, 2022 20:28


Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Internal Medicine Audio
Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Internal Medicine Audio

Play Episode Listen Later Mar 29, 2022 20:28


Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Internal Medicine Video
Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Internal Medicine Video

Play Episode Listen Later Mar 29, 2022 20:14


Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Clinical Pharmacology Video
Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Clinical Pharmacology Video

Play Episode Listen Later Mar 29, 2022 20:14


Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Brain & Behaviour Video
Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Brain & Behaviour Video

Play Episode Listen Later Mar 29, 2022 20:14


Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Brain & Behaviour Audio
Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

PeerVoice Brain & Behaviour Audio

Play Episode Listen Later Mar 29, 2022 20:28


Suspecting and Diagnosing Inherited Retinal Dystrophies: Early Clues and Confirmatory Testing

Renewal Ministries:

confirmatory
Turn Learning Into Practice
Airport Security: Confirmatory Tests

Turn Learning Into Practice

Play Episode Listen Later May 17, 2021 4:55


The goal of this podcast is to provide clinicians with a better understanding of test specificity and how to apply this statistic in diagnostic decision-making.

Naruhodo
Naruhodo #272 - Quais são os grandes desafios da psicologia no Brasil?

Naruhodo

Play Episode Listen Later Feb 22, 2021 54:41


O podcast Naruhodo é um crítico da formação de psicólogas e psicólogos em nosso país.Por quê? E quais são os principais desafios da psicologia no Brasil?Confira no papo entre o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.OUÇA (54min 41s)*Naruhodo! é o podcast pra quem tem fome de aprender. Ciência, senso comum, curiosidades, desafios e muito mais. Com o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.Edição: Reginaldo Cursino.http://naruhodo.b9.com.br*PARCERIA: ALURAA Alura tem mais de 1.000 cursos de diversas áreas e é a maior plataforma de cursos online do Brasil -- e você tem acesso a todos com uma única assinatura.Aproveite o desconto de R$100 para ouvintes Naruhodo no link:https://www.alura.com.br/promocao/naruhodo *REFERÊNCIASThe Four Causes of Hypnosishttps://www.tandfonline.com.sci-hub.st/doi/abs/10.1076/iceh.51.3.195.15522The human person in modern psychological sciencehttps://bpspsychub.onlinelibrary.wiley.com/doi/abs/10.1111/j.2044-8341.1970.tb02121.xOxford Handbook of Causation (cap 21-23)https://books.google.com.br/books/about/The_Oxford_Handbook_of_Causation.html?id=xGnZtUtG-nIC&printsec=frontcover&source=kp_read_button&redir_esc=y#v=onepage&q&f=falseCan robots make good models of biological behaviour?https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.85.9059&rep=rep1&type=pdfPredict, Control, and Replicate to Understand: How Statistics Can Foster the Fundamental Goals of Sciencehttps://www.researchgate.net/publication/327452010_Predict_Control_and_Replicate_to_Understand_How_Statistics_Can_Foster_the_Fundamental_Goals_of_SciencePsicanálise é ciência?https://www.b9.com.br/shows/naruhodo/naruhodo-76-psicanalise-e-ciencia/Psicanálise é ciência? Ou pseudociência? | Christian Dunker | Falando nIsso 126https://www.youtube.com/watch?v=x_6NMVGGBQE&ab_channel=ChristianDunkerPsicanálise é ciência? Definindo os conceitos | Christian Dunker | Falando nIsso 127https://www.youtube.com/watch?v=CoP4rUheVyU&ab_channel=ChristianDunkerPsicanálise é ciência? Críticas à psicanálise | Christian Dunker | Falando nIsso 128https://www.youtube.com/watch?v=DX_3LzEpjHM&ab_channel=ChristianDunkerPsicanálise é ciência? | Christian Dunker | Falando nIsso 129https://www.youtube.com/watch?v=8D09T7i6RZ4&ab_channel=ChristianDunkerSubliminal unconscious conflict alpha power inhibits supraliminal conscious symptom experiencehttps://www.frontiersin.org/articles/10.3389/fnhum.2013.00544/fullEquivalence relations do exist before they are tested: Confirmatory evidence revealed by EEG measurementshttps://onlinelibrary.wiley.com/doi/10.1002/jeab.662Podcasts das #Minas: RAD ON - Radiação para leigos#MulheresPodcastershttps://open.spotify.com/show/0CaHzigpWGnSgnG7z4Zb0D*APOIE O NARUHODO!Você sabia que pode ajudar a manter o Naruhodo no ar?Ao contribuir, você pode ter acesso ao grupo fechado no Telegram, receber conteúdos exclusivos e ter vantagens especiais.Assine o apoio mensal pelo PicPay: https://picpay.me/naruhodopodcast

Lehigh University Business Blog - Spoken Edition
Will Confirmatory Bias Keep You from Getting COVID-19 Vaccine?

Lehigh University Business Blog - Spoken Edition

Play Episode Listen Later Oct 6, 2020 29:16


The old saying that you don't get a second chance to make a first impression is especially true when it comes to vaccines, according to a study by two College of Business economics researchers. If the first opinion people form about a new COVID-19 vaccine is negative, it will be difficult to rebuild public trust.

PaperPlayer biorxiv neuroscience
Confirmatory evidence that healthy individuals can adaptively adjust prior expectations and interoceptive precision estimates

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Sep 1, 2020


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.31.275594v1?rss=1 Authors: Smith, R., Kuplicki, R., Teed, A., Upshaw, V., Khalsa, S. S. Abstract: Theoretical proposals have previously been put forward regarding the computational basis of interoception. Following on this, we recently reported using an active inference approach to 1) quantitatively simulate interoceptive computation, and 2) fit the model to behavior on a cardiac awareness task. In the present work, we attempted to replicate our previous results in an independent group of healthy participants. We provide evidence confirming our previous finding that healthy individuals adaptively adjust prior expectations and interoceptive sensory precision estimates based on task context. This offers further support for the utility of computational approaches to characterizing the dynamics of interoceptive processing. Copy rights belong to original authors. Visit the link for more info

Grace Testament Church Podcast
Enhanced Christian Quality Part 4: Confirmatory Tests

Grace Testament Church Podcast

Play Episode Listen Later May 12, 2020 55:14


Crisis reveals a man—Show yourself for real in relation to God and His people! Listen to Pastor Rafy Panlilio as he continues our Enhanced Christian Quality series, "Confirmatory Tests."

The Modern Therapist's Survival Guide with Curt Widhalm and Katie Vernoy

Curt and Katie talk about the ins and outs of intuition. We look at when you can trust your gut feelings and when you cannot. We sort through how to actually develop and use clinical intuition as well as the problems that can come into play when you do not follow the appropriate steps.       It’s time to reimagine therapy and what it means to be a therapist. To support you as a whole person and a therapist, your hosts, Curt Widhalm and Katie Vernoy talk about how to approach the role of therapist in the modern age. In this episode we talk about: Definitions of the 4 types of intuition: mystical, spurious, inferential, wholistic Confirmatory bias – how it can be known, but go unrecognized How operant conditioning might be supporting your feeling of being able to trust your gut Discounting affect (ignoring when your assumptions were wrong) Whether or not we should pay attention to Mercury in Retrograde The challenge of looking for evidence that both supports and challenges your assumptions The different individual characteristics that get in the way of evaluating things appropriately The importance of deliberate practice The two different thinking processes described by Daniel Kahneman in Thinking Fast and Slow The need to test our assumptions, even though it is potentially laborious or threatening Using the scientific method The problem with “mindbugs” like the availability heuristic and the misinformation effect in trying to actively improve our ability to assess data Deductive intuition versus inductive intuition Conditions required to use clinical intuition: regularity, practice, immediate feedback Looking for things that prove you wrong, hearing and sorting through both positive and negative feedback A danger of specialization where you fit every client into your area of focus The left brain/right brain fallacy When case examples or individual stories don’t honor all of the times that clinicians are wrong Unexamined bias is a constant challenge in trying to make sure you are evaluating the actual data and not what you are expecting to see Resources mentioned: We’ve pulled together resources mentioned in this episode and put together some handy-dandy links. Please note that some of the links below are affiliate links, so if you purchase after clicking below, we may get a little bit of cash in our pockets. We thank you in advance! Glyn Brokensha – Clinical Intuition: more than rational? Blindspot: Hidden Biases of Good People by Mahzarin R. Banaji and Anthony G. Greenwald Thinking Fast and Slow by Daniel Kahneman Awakening Intuition by Terry Marks-Tarlow   Therapy Reimagined 2020 Call for Speakers Therapy Reimagined 2020 Call for Sponsors   Relevant Episodes and Blog Posts: Saying “Trust Your Gut” Is Bad Advice Deliberate Practice episodes: Be a Better Therapist Finding Your Blindspots   Connect with us! Our Facebook Group – The Modern Therapists Group Get Notified About Therapy Reimagined 2020 (and TR2019 Virtual Conference)   Our consultation services: The Fifty-Minute Hour   Who we are: Curt Widhalm is in private practice in the Los Angeles area. He is the cofounder of the Therapy Reimagined conference, the CFO of the California Association of Marriage and Family Therapists, an Adjunct Professor at Pepperdine University, a former Subject Matter Expert for the California Board of Behavioral Sciences, and a loving husband and father. He is 1/2 great person, 1/2 provocateur, and 1/2 geek, in that order. He dabbles in the dark art of making "dad jokes" and usually has a half-empty cup of coffee somewhere nearby. Learn more at: www.curtwidhalm.com Katie Vernoy is a Licensed Marriage and Family Therapist, coach, and consultant supporting leaders, visionaries, executives, and helping professionals to create sustainable careers. Katie, with Curt, has developed workshops and a conference, Therapy Reimagined, to support therapists navigating through the modern challenges of this profession. Katie is also President of the California Association of Marriage and Family Therapists. In her spare time, Katie is secretly siphoning off Curt's youthful energy, so that she can take over the world. Learn more at: www.katievernoy.com A Quick Note: Our opinions are our own. We are only speaking for ourselves – except when we speak for each other, or over each other. We’re working on it. Our guests are also only speaking for themselves and have their own opinions. We aren’t trying to take their voice, and no one speaks for us either. Mostly because they don’t want to, but hey.   Stay in Touch: www.mtsgpodcast.com www.therapyreimagined.com Our Facebook Group – The Modern Therapist’s Group https://www.facebook.com/therapyreimagined/ https://twitter.com/therapymovement https://www.instagram.com/therapyreimagined/   Credits: Voice Over by DW McCann https://www.facebook.com/McCannDW/ Music by Crystal Grooms Mangano http://www.crystalmangano.com/

Playing with Research in Health and Physical Education
69: Structural Equation Modeling and Confirmatory Factor Analysis

Playing with Research in Health and Physical Education

Play Episode Listen Later Nov 26, 2019 23:45


Kevin Richards (@KARRichards14) comes on to discuss the statistics used in his co-authored paper (see cite below). This is a good real-world application and explanation to these two techniques. The podcast about the paper launches next week (Episode 70). Full Cite: Richards, K. A. R., Washburn, N., & Lee, Y. H. (2019). Understanding Emotional Labor in Relation to Physical Educators’ Perceived Organizational Support, Affective Commitment, and Job Satisfaction. Journal of Teaching in Physical Education, 1(aop), 1-11.

Renewal Ministries:

confirmatory
The Nigel Farage Show
Confirmatory Referendum

The Nigel Farage Show

Play Episode Listen Later May 27, 2019 41:35


Is there an appetite from you for a confirmatory referendum this follows Keir Starmer's comments that is has been raised in discussions with the PM

Lehigh University Business Blog - Spoken Edition
Vaccination: When ‘Fake News’ Has Lasting Consequences

Lehigh University Business Blog - Spoken Edition

Play Episode Listen Later Apr 10, 2019 4:31


Science has long concluded there is no link between vaccines and autism. So why do some people refuse to believe it? Confirmatory bias helps explain.

Podcasts360
More Adults Are Reporting Food Allergies. What Can We Do?

Podcasts360

Play Episode Listen Later Jan 22, 2019 12:10


Confirmatory testing for food allergies and epinephrine carriage are more important than ever, now that new findings reveal greater numbers of US adults reporting food allergies. In this podcast, Dr Ruchi S. Gupta, of the Northwestern University Feinberg School of Medicine, and Christopher Warren, of the Keck School of Medicine of USC, discuss their research and the role of primary care providers in diagnosing food allergies. For more, visit www.consultant360.com.

The Knowledge Project with Shane Parrish
#37 Annie Duke: Getting Better by Being Wrong

The Knowledge Project with Shane Parrish

Play Episode Listen Later Jul 24, 2018 116:32


I have wanted to do this interview for a long time. On this episode, I am thrilled to have Annie Duke, former professional poker player and author of the new book, Thinking in Bets: Making Smarter Decisions When You Don't Have All the Facts. Annie has a very interesting background that makes her uniquely qualified to speak about high-level decision making. As an author, speaker, world-class poker player, and academic in the fields of psychology and cognitive theory, Annie understands the intersection of luck, skill, and making decisions in uncertain, chaotic environments better than most people on the planet. This is a whirlwind of an episode, and we cover all kinds of fascinating topics, including: The strange circumstances that shifted Annie’s path from finishing a Ph.D. in linguistics to becoming a professional poker player What it was like to be a female poker player in a predominantly male sport (especially before poker had become socially acceptable) What drew Annie into such a high stakes, time-pressured environment and why she felt like poker was the perfect fit for her How her graduate work in psychology informed the way she approached the game of poker — and helped her rack up wins How she finds the signal in a very noisy stream of feedback The big mistakes Annie noticed other players making that were stalling their progress in the game but allowed her to make giant leaps forward The role that mental models played in her learning process (and which models Annie liked to lean on the most in a high stakes game) The power of surrounding yourself with people that can help you expand your circle of competence — and how that made all the difference in Annie’s development as a player Confirmatory and exploratory thought, and how one helps us to be “accurate” and one helps us to be “right.” The secret pact you should be making with the people who are closest to you And so much more. This episode is just under two hours long, but there’s no fat in it. Annie delivers a masterclass in making the smartest decisions we can, even when our hubris insists otherwise. Do some finger stretches before hitting play, because you’re going to be taking some serious notes. Please enjoy the interview! *** GO PREMIUM: Support the podcast, get ad-free episodes, transcripts, and so much more: https://fs.blog/knowledge-project-premium/  

Renewal Ministries:

confirmatory
Your Parenting Mojo - Respectful, research-based parenting ideas to help kids thrive

  (Believe it or not, this is Carys’ “I freaking love homemade spinach ravioli with broccoli” face!)   I was sitting in a restaurant recently with half an eye on a toddler and his parents at the next table. The parents were trying to get the toddler to eat some of his broccoli before he ate the second helping of chicken that he was asking for. All of a sudden a line from Pink Floyd’s album “The Wall” popped into my head: If you don’t eat yer meat, you can’t have any pudding. How can you have any pudding if you don’t eat yer meat? This is the way I was raised; you finish everything on your plate and you certainly don’t get dessert if you don’t finish your meal. But as is the custom with the Your Parenting Mojo podcast, I want to use this episode to question why we do this and find out what scientific research has to say about it all. We want our toddlers to eat a balanced diet, and we assume we have to teach them what a balanced diet means. But do we really? Or can we trust that our children will eat the foods that they need to be healthy? These are some of the questions we’ll set out to answer in this episode. References Benton, D. (2004). Role of parents in the determination of the food preferences of children and the development of obesity. International Journal of Obesity 28, 858-869. DOI: 10.1038/sj.ijo.0802532 Birch LL. (1980). Effects of peer models’ food choices and eating behaviors on preschoolers’ food preferences. Child Development 51, 489–496. Birch, LL., Marlin, D.W., & Rotter, J. (1984). Eating as the ‘means’ activity in a contingency: Effects on young children’s food preferences. Child Development 55, 432-439. Retrieved from: https://www.jstor.org/stable/1129954?seq=1#page_scan_tab_contents Birch, L.L., & Fisher, J.O. (1998). Development of eating behaviors among children and adolescents. Pediatrics 101 Issue supplement 2. Retrieved from: http://pediatrics.aappublications.org/content/101/Supplement_2/539 Birch, L.L., Fisher, J.O., Grimm-Thomas, K., Markey, C.N., Sawyer, R., & Johnson, S.L. (2001). Confirmatory factor analysis of the Child Feeding Questionnaire: A measure of parental attitudes, beliefs and practices about child feeding and obesity proneness. Appetite 36, 201-210. DOI: 10.1006/appe.2001.0398 Davis, C.M. (1939). Results of the self-selection of diets by young children. Canadian Medical Association Journal 41, 257-61. Full article available at: (http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=537465&blobtype=pdf) Fisher, J.O., & Birch, L.L. (1999). Restricting access to foods and children’s eating. Appetite 32(3), 405-419. DOI: 10.1006/appe.1999.0231 Hughes, S.O., Power, T.G., Orlet Fisher, J., Mueller, S., & Nicklas, T.A. (2005). Revisiting a neglected construct: Parenting styles in a child feeding context. Appetite 44(1), 83-92. DOI: 10.1016/j.appet.2004.08.007 (http://dx.doi.org/10.1016/j.appet.2004.08.007) Jansen, E., Mulkens, S., & Jansen, A. (2007). Do not eat the red food!: Prohibition of snacks leads to their relatively higher consumption in children. Appetite 49(3), 572-577. DOI: 10.1016/j.appet.2007.03.229 Jansen, E., Mulkens, S., Emond, Y., & Jansen, A. (2008). From the Garden of Eden to the land of plenty: Restriction of fruit and sweets intake leads to increased fruit and sweets consumption in children. Appetite 51(3), 570-575. DOI: 10.1016/j.appet.2008.04.012 Newman, J., & Taylor, A. (1992). Effect of a means-end contingency on young children’s food preferences. Journal of Experimental Child Psychology, 64, 200-216. DOI: 10.1016/0022-0965(92)90049-C Pink Floyd (1979). Another brick in the wall – Part 2. London, Metro-Goldwyn-Mayer. Lyrics retrieved from: http://www.pink-floyd-lyrics.com/html/another-brick-2-wall.html (http://www.pink-floyd-lyrics.com/html/another-brick-2-wall.html) Savage, J.S., Fisher, J.O., & Birch, L.L....

Medizin - Open Access LMU - Teil 17/22
Alpha-Lipoic Acid for the Prevention of Diabetic Macular Edema

Medizin - Open Access LMU - Teil 17/22

Play Episode Listen Later Jan 1, 2011


Introduction: To evaluate the effect of alpha-lipoic acid (ALA) on the occurrence of diabetic macular edema. Methods: Randomized, double-blind, placebo-controlled, multicenter, multinational study. Patients were randomized to the treatment group with 600 mg ALA per day or the placebo group. Every 6 months stereo fundus photographs, HbA1c levels, and an ophthalmological examination were documented. The primary endpoint was the occurrence of clinically significant macular edema (CSME) within a follow-up period of 2 years. Results: We randomized 235 patients with type II diabetes mellitus into the treatment group (mean age 58.0 years) and 232 into the placebo group (mean age 57.9 years). Mean HbA1c level was 8.1, with no significant differences between the treatment (mean 8.2, SD +/- 1.35) and placebo groups (mean 8.1, SD +/- 1.29). HbA1c values remained constant over time. In the treatment and placebo groups, 84 and 86 patients (35.7 and 37.1%) had insulin-dependent diabetes mellitus (IDDM) with a median duration of diabetes of 9.3 versus 9.0 years in the placebo group. Visual acuity remained unchanged during the entire trial. Concerning the primary endpoint, the study provided a negative result, i.e. 26/235 patients in the treatment group and 30/232 patients in the placebo group developed CSME. Confirmatory intention-to-treat analysis of the primary endpoint revealed no statistically significant difference between groups (log-rank test, p = 0.7108, HR = 0.9057 with CI = 0.5355-1.5317). Median follow-up was identical (2.00 years). Conclusions: A daily dosage of 600 mg ALA does not prevent the occurrence of CSME in IDDM patients. Copyright (C) 2011 S. Karger AG, Basel