Podcast appearances and mentions of rich miller

For this episode of the Data Center Frontier Show Podcast, DCF Editor in Chief Matt Vincent and Senior Editor David Chernicoff sat down for a far-reaching discussion with data center industry luminary Ron Vokoun, a 35-year veteran of the construction industry with a primary focus on digital infrastructure.  "I got into telecom back in '92, which led to data centers," he said. "Probably worked on my first one around '96 or '97, and I've been involved ever since." Currently the Director of National Market Development for Everus Construction Group, Vokoun has been involved in AFCOM, both regionally and nationally, for nearly two decades and is an emeritus content advisory board member for Data Center World. He has also written extensively for Data Center Dynamics. Vokoun added, "I've just always been curious—very much a learner. Being a construction guy, I often write about things I probably have no business writing about, which is always the challenge, but I'm just curious—a lifelong learner. Interestingly, [DCF founder] Rich Miller ... gave me my first blogging opportunity." Here's a timeline of the podcast's highlights: Introductions  - Ron Vokoun shares his extensive background. He has been in the construction industry for 35 years. 1:46 - On his role at Everus Construction Group and the company's diverse services across the nation. 2:07 - Vokoun reflects on his long-standing relationship with Rich Miller. He acknowledges Rich's influence on his blogging career. 3:05 Nuclear Energy  - A discussion about nuclear energy trends occurs. The importance of nuclear energy in data center construction is probed. 3:35 - Natural gas is highlighted as a key trend. Its role as a gateway to hydrogen is emphasized. 3:51 - The impact of recent nuclear developments is analyzed. The reopening of Three Mile Island is noted as significant. 4:55 Future Power Sources for Data Centers  - Discussion turns to the timeline for small modular reactors (SMR). Vokoun expresses some confidence that significant developments will occur within five years. 5:42 - Natural gas is identified as a potential primary power source. Its role as a cleaner alternative to diesel generators is acknowledged. 7:49 Natural Gas Interest   - Vokoun talks about how natural gas generators are being considered by major companies, and how much more implementation is anticipated in the near future. 9:18 - The advantages of multiple power sources are emphasized. Vokoun remarks on how natural gas plants can adjust more quickly than nuclear or coal plants. 10:53 Power Project Lawsuits and Concerns  - Concerns about the impact on residential customers are raised. The relocation of power from one vendor to another is discussed. 12:12 - The potential for increased power generation is highlighted. A net decarbonization effect is suggested due to more carbon-free power sources. 12:59 Impact of Liquid Cooling   - Discussion centers on advancements in power distribution. Insights are shared on liquid cooling infrastructure trends. 13:34 - Direct liquid cooling is noted as prevalent. Immersion cooling is mentioned as having lost traction. 16:06 Immersion Cooling Technologies  - A discussion about immersion cooling technologies occurs. The efficiency of direct to chip cooling is emphasized. 17:12 - Concerns regarding the weight of new racks are raised. The need for plumbing in liquid cooling systems is highlighted. 17:48 - The potential narrowing of the immersion cooling market is predicted. A quick market response is anticipated based on immersion cooling's market share. 19:00 Energy Storage Technologies Overview   - The advantages of various energy storage technologies are discussed. Lead acid, lithium ion, and sodium solutions are mentioned as key options. 20:00 - The shift in market share from lead acid batteries is highlighted. Sodium-based products are noted as an exciting emerging technology. 20:41 - Data centers in new locations are referenced. 21:50 Evolving Site Selection Criteria   - The evolution of site selection for data centers is discussed. The importance of having reliable power sources is emphasized. 22:57 - The rise of data center locations in Indiana is highlighted, as an example of how previously overlooked areas are now experiencing significant development. 24:01

At last, New York City started its congestion pricing program on January 5. We knew that the local mainstream press would be out in force interviewing drivers and elevating the voices of those who were against the toll. We knew that because the New York press corps has a long history of putting the people who commute by car in New York above those who don't.  So we went out on congestion pricing's first weekday morning and talked to some people who weren't driving. Some of the people we talked with were random New Yorkers, but mostly we heard from advocates who knew we would be there and showed up in the freezing cold to talk about why they were so excited about the launch of this historic program. Thank you to all the people who spared some of their time on a cold morning to talk to us, especially Samir Lavingia, Charlie Todd, Chris Sanders, Alex Duncan, Rich Miller, Noel Hidalgo, Seth Solomonow, Kirby Kersels, Paul Krikler and Steve from Peekskill. This episode was edited by Ali Lemer.  *** Support The War on Cars on Patreon and receive exclusive access to bonus content, ad-free versions of regular episodes, free stickers, merch discounts, early access to live shows, and more. ***  LINKS: The MTA's FAQ page answers all your questions about congestion pricing. Check out this congestion pricing traffic tracker for collected data showing the program's impact. TheWarOnCars.org  

Rich Miller, founder of the leading digital infrastructure publications Data Center Knowledge and Data Center Frontier, shares his unique career journey in a recent episode of the Nomad Futurist Podcast with co-hosts Nabeel Mahmood and Phillip Koblence. His journalistic focus evolved over the decades of his career, highlighting the importance of adapting readily to new circumstances and following one's passions.Miller got his journalism start in high school, where he started writing about sports for the school newspaper. This early experience led him to pursue journalism at Rutgers University, where he honed his skills at the student newspaper, The Daily Targum:"Covering sports on deadline ... was one of the best training exercises you could have for a career in journalism. You really learned everything that you need to know to succeed."After years of covering sports, Miller decided to pursue a change of pace, making a strategic shift to business journalism. In a surprising turn of events, his first day coincided with a significant event in financial history:"My first day on the business desk was October 19th, 1987, which was the day that the DOW fell 22%. So I got to jump right into a major story happening in my first day on business."Feeling pulled to a new direction after spending some time in the business world, Miller found himself drawn to technology reporting as the internet began to emerge as a transformative force. His years in the journalism industry allowed him to see the internet's potential as a publishing medium early on:"The first time I logged onto America Online, it was a revelation. It was like, oh, this isn't just about reading stuff. This is a publishing medium that immediately took all of the cost out of the equation."His fascination with technology already budding, Miller's entry into the world of data centers came through a chance encounter when he was told to walk through a data center. After being introduced to the concept of carrier hotels and data centers, he had a pivotal experience:"You walk into the data center and this entire world reveals itself ... I'm just looking everywhere at this world and it made that connection, the light bulb went off over my head."This experience led Miller to recognize the growing importance of data center infrastructure in the digital age, igniting a new passion and setting the stage for his future career focus. His journey from sports writing to technology journalism is a testament to how being versatile and eager to explore new areas of interest can create opportunity.To learn more about Rich Miller, connect with him on LinkedIn.

Faithing The New Year - Rich Miller, New Life Elder - 12 29 24 by New Life of Asheville

President Muhammad Faridi hosts Rich Miller (former Chief of Energy Policy for New York City and former Vice President of Energy and Environmental Law at Con Edison) and Robie Craig (Senior Energy Council at the New York City Department of Citywide Administrative Services), Co-Chairs of the City Bar Energy Law Committee. The conversation touches on various aspects of energy policy and its relevance to New York City, including historical perspectives on power generation, the current shift towards clean energy, and the implementation of regulatory mandates such as the Climate Leadership and Community Protection Act (CLCPA) and the Build Public Renewables Act. Muhammad, Rich and Robie also explore the city's efforts to balance environmental justice with the need for reliable energy supply, the role of Con Edison, challenges posed by intermittent renewable sources, and the steps New York City is taking to support electric vehicle adoption. Access a transcript of this episode here: https://bit.ly/3XhBhtK Want to learn more about the impact of energy decisions and environmental justice? Join us at the City Bar's upcoming programs: The Professional Duty of Lawyers and Bar Associations in Action on Climate on September 23 (https://bit.ly/3XsQhFh) and Economic and Environmental Impacts of State and City Funded Remediation Programs on Environmental Justice Communities in NYC on October 29 (https://bit.ly/3XrirQL). Visit nycbar.org/events to find all of the most up-to-date information about our upcoming programs and events. 00:00 Introduction and Welcome 03:46 Understanding DCAS and Con Edison 11:15 New York City's Energy Landscape 16:58 Historical Perspective: The Birth of Electricity in NYC 23:52 Regulatory Framework and Environmental Justice 35:49 Future of Clean Energy and Transportation in NYC 49:03 Committee Focus and Closing Remarks

The Mic'd In New Haven returns to the airwaves after a summer hiatus with Volume 48 of The E-Men: Inside The NYPD's Emergency Service Unit featuring veteran Bronx Truck 4 E-Man Rich Miller. In Memory Of: Sergeant John G. Coughlin Emergency Service Squad No. 4 Sergeant Michael S. Curtin Emergency Service Squad No. 2 Sergeant Rodney C. Gillis Emergency Service Squad No. 8 Detective Joseph V. Vigiano Emergency Service Squad No. 2 Police Officer John D'Allara Emergency Service Squad No. 2 Police Officer Vincent G. Danz Emergency Service Squad No. 3 Police Officer Jerome M. Dominguez Emergency Service Squad No. 3 Police Officer Stephen P. Driscoll Emergency Service Squad No. 4 Police Officer Ronald P. Kloepfer Emergency Service Squad No. 7 Police Officer Thomas M. Langone Emergency Service Squad No. 10 Police Officer Brian G. McDonnell Emergency Service Squad No. 1 Police Officer Paul Talty Emergency Service Squad No. 10 Police Officer Santos Valentin Jr. Emergency Service Squad No. 7 Police Officer Walter E. Weaver Emergency Service Squad No. 3 (End of Watch: September 11, 2001) Connect With Mike Colón: X: https://x.com/mikeinnewhaven Instagram: https://instagram.com/mikecolo... Facebook: https://www.facebook.com/MikeC... LinkedIn: https://www.linkedin.com/newsl... Media Website: https://mike-colon-media.com/ Consulting Website: https://www.mcmediaeditingserv... Business Line: 917-781-6189 Media Email: thecolonreport@gmail.com Consulting Email: mike@mcmediaeditingservicesllc.com Connect With Producer Vick: Instagram: https://www.instagram.com/prod... Listen To The Podcast: iTunes: https://podcasts.apple.com/us/... iHeart: https://www.iheart.com/podcast... Spreaker: https://www.spreaker.com/show/... Spotify: https://open.spotify.com/show/... PlayerFM: http://front.player.fm/series/... Google Podcasts: https://podcasts.google.com/se... Amazon: https://music.amazon.com/podca... YouTube (Video Version): https://www.youtube.com/live/V... Sponsors: MC Media Editing Services: https://www.mcmediaeditingserv... Ryan Investigative Group LLC:https://www.ryaninvestigators.... Outro Song: Lynyrd Skynyrd - Simple Man (1973)Become a supporter of this podcast: https://www.spreaker.com/podcast/mic-d-in-new-haven--2828702/support.

These are indeed challenging times. How does one stay calm, focused, and effective during difficult times and what does gratitude have to do with it? What is at the core of gratitude? How is it relevant to leadership, and how does one successfully employ it as a method for greater effectiveness during trying times? Join host Dr. Sheryl White, cultural psychologist with the Neighborhood House Association in San Diego, CA; Rich Miller, Senior Pastor of Perfecting Grace Church in San Diego, CA; and Cedric Manley, Founder and CEO of Family Synergy Center in Dallas, TX, as they discuss leadership and the power of gratitude in challenging times.

En este episodio vas a aprender sobre los verbos clave que puedes usar para hablar de accidentes y heridas. ¡Pon mucha atención porque hay mucha información valiosa! Pero hoy haremos algo diferente: hemos invitado a Rich Miller, un estudiante de nuestro curso en línea, él va a traducir frases usando este vocabulario clave y tú aprenderás a través de sus errores. Es decir, él va a estar reemplazando a Nate. Si quieres estudiar todo el vocabulario de Accidentes y Heridas escucha el episodio 371 aquí: https://www.espanolistos.com/accidentes-y-heridas/ ¿Realmente quieres llevar tu español al siguiente nivel? Conviértete en uno de nuestros estudiantes aquí. Tenemos todas las herramientas, estructura y rutina que necesitas para salir del nivel intermedio y moverte hacia el avanzado. ¿Qué contiene nuestra membresía? 1 Clase en vivo (webinar) de 1 hora cada semana enfocadas en un tema específico cada mes. 8 Lecciones mensuales ( 4 enfocadas en un mismo tema de gramática y 4 lecciones de comprensión auditiva) +30 cursos de gramática y comprensión auditiva en una plataforma. Podcast privado con el contenido de las lecciones del mes. Videollamadas en grupos de 4 al final del mes y mucho más. ¡Revisa los detalles y regístrate para nuestro curso de español continuo ahora! Descarga la transcripción de este episodio aquí: https://www.espanolistos.com/

The latest episode of the Data Center Frontier Show Podcast presents an Editors' Summit of sorts, as DCF's founder and Editor at Large Rich Miller drops by to join in the discussion with Editor in Chief Matt Vincent and Senior Editor David Chernicoff. The editors discuss the challenges of power availability in leading data center markets and the concept of Gigawatt data Center campuses (as reflected by Rich's latest article) as a solution, focusing on renewable energy and innovative designs. Microsoft's commitment to ten gigawatts of renewable energy, as well as the Infrastructure Masons recommendation of clean energy parks amounting to about the same, is mentioned, along with the challenges posed by climate change and the need for innovation in renewable energy.  The pricing out of small data centers due to demand from hyperscalers is also discussed, as were the present, burgeoning prospects for nuclear energy to power the data center industry, including the absolutely accelerating nuclear SMR frontier, of which much was heard at Data Center World (Apr. 15-18) in Washington, DC.

We have a jam-packed episode for you today! Our feature conversation is with Rich Miller, Jr.  He's a NFL Draft prospect that went to Martin Luther King Jr. High School in Detroit. It's a fascinating conversation on his story. And Fletcher Sharpe has even more for you. Here's the rundown: 01:05 - The Pistons are looking for a new Head of Basketball Operations, but Troy Weaver is staying 03:00 - NFL Draft prospect Rich Miller Jr. joins us to talk about his time at MLK high School. Here are time stamps in the conversation portion:  04:37 - What made him choose to go to Buffalo for college after high school? 06:34 - How has being from Detroit help mold him as a person and a football player? 10:45 - What is the perfect senerio for the Draft? 12:19 - How big of a deal is it for him that the draft is in Detroit? 13:16 - First stop once he gets home? 13:52 - Advice for younger people coming up From Hamtramck: 16:43 - Detroit City FC wins 1-0 in an Open Cup match against the Michigan Stars. Is it now a rivalry? Fletcher has thoughts. As always, you can find Daily Detroit on Apple Podcasts, Spotify, or wherever you download your favorite podcasts. On Apple: https://lnk.to/dailydetroitonapple  On Spotify: https://lnk.to/dailydetroitonspotify  Thanks to our members on Patreon. Local coverage requires local support: http://www.patreon.com/dailydetroit  

For this episode of the Data Center Frontier Show podcast, it's financial earnings call season, so Editor in Chief Matt Vincent and Senior Editor David Chernicoff take the opportunity to discuss DCF's top 5 most popular data center and cloud computing industry stories for the fourth quarter of 2023, which were as follows:  1. Dominion: Virginia's Data Center Cluster Could Double in Size Dominion Energy says it has customer contracts that could double the amount of data center capacity in Virginia by 2028 and is planning new power lines to support this growth. Virginia is already the world's largest market for cloud computing infrastructure. Despite the current power constraints around Ashburn, the data center market in Virginia is positioned to grow much larger. The utility says it has received customer orders that could double the amount of data center capacity in Virginia by 2028, with a projected market size of 10 gigawatts by 2035. That represents a huge increase from current data center power use, which reached 2.67 gigawatts in 2022. The utility's projections mean that Virginia will continue to experience tensions between the growth of the Internet and the infrastructure to support it. Data Center Frontier's Founder and Editor at Large, Rich Miller, reports. 2. Microsoft Unveils Custom-Designed Data Center AI Chips, Racks and Liquid Cooling At Microsoft Ignite last November, the company unveiled two custom-designed chips and integrated systems resulting from a multi-step process for meticulously testing its homegrown silicon, the fruits of a method the company's engineers have been refining in secret for years, as revealed at its Source blog. The end goal is an Azure hardware system that offers maximum flexibility and can also be optimized for power, performance, sustainability or cost, said Rani Borkar, corporate vice president for Azure Hardware Systems and Infrastructure (AHSI). “Software is our core strength, but frankly, we are a systems company. At Microsoft we are co-designing and optimizing hardware and software together so that one plus one is greater than two,” Borkar said. “We have visibility into the entire stack, and silicon is just one of the ingredients.” The newly introduced Microsoft Azure Maia AI Accelerator chip is optimized for artificial intelligence (AI) tasks and generative AI. For its part, the Microsoft Azure Cobalt CPU is an Arm-based processor chip tailored to run general purpose compute workloads on the Microsoft Cloud. Microsoft said the new chips will begin to appear by early this year in its data centers, initially powering services such as Microsoft Copilot, an AI assistant, and its Azure OpenAI Service. They will join a widening range of products from the company's industry partners geared toward customers eager to take advantage of the latest cloud and AI technology breakthroughs. 3. The Eight Trends That Will Shape the Data Center Industry in 2023 Rich Miller predicted that 2023 would be a year of dueling cross currents that could constrain or accelerate business activity in the sector. DCF's Vincent and Chernicoff briefly review last year's trends, remarking on how so many of them are still in full effect for the industry right now. Scorecard: Looking Back at Data Center Frontier's 2023 Industry Predictions 4.  Google Is Now Reducing Data Center Energy Use During Local Power Emergencies Last October, Google shared details of a system optimized to reduce the energy use of data centers when there is a local power emergency. Core functions of the system, which has the hallmarks of a universally applicable technology, include postponing low-priority workloads, and moving others to other regions that are less constrained. Regarding the system, Michael Terrell, Google's Senior Director for Energy and Climate, explained in a LinkedIn post how the new demand response capability can temporarily reduce power consumption from Google data centers when it's needed, and provide flexibility to the local grids that power its data center operations. Demand response helps grid operators serve their customers reliably during times of need, such as in times of supply constraints or extreme weather events. Terrell's post empasized that "demand response can be a big tool to help grids run more cost-effectively and efficiently, and it can accelerate system-wide grid decarbonization." Google's Climate and Energy teams created the new system, which Terrell called an important development toward running the company's data centers "intelligently, efficiently and carbon-free." 5. Cloudflare Outage: There's Plenty Of Blame To Go Around The Cloudflare outage in the first week of November drew quite a bit of attention, not only because Cloudflare's services are extremely popular, so their failure was quickly noticed, but also because of the rapid explanation of the problem posted in the Cloudflare Blog shortly after the incident. This explanation placed a significant portion of the blame squarely on Flexential and their response to the issues with electricity provider PGE, and potential issues that PGE was having. Cloudflare was able to restore most of its services in 8 hours at its disaster recovery facility. It runs its primary services at three data centers in the Hillsboro, Oregon area, geolocated in such a way that natural disasters are unlikely to impact more than a single data center. DCF's David Chernicoff noted, "While almost all of the coverage of this incident starts off by focusing on the problems that might have been caused by Flexential, I find that I have to agree with the assessment of Cloudflare CEO Matthew Prince: To start, this never should have happened.” Here are links to some related DCF articles: DCF Show: Data Center Frontier's Rich Miller Returns For a Visit DCF Tours: Flexential Dallas-Plano Data Center, 18 MW Colocation Facility Meta Previews New Data Center Design for an AI-Powered Future For Leading Cloud Platforms, AI Presents a Major Opportunity AI Propels Cloud Growth, Digital Infrastructure Investment to New Heights  

This month on the Data Center Frontier Show podcast, we read down site founder and Editor at Large Rich Miller's annual data center industry trends forecast. This week's article read looks at how AI is driving design updates for power and cooling, why air permitting at scale is a hot potato for the industry, and optimal site selection for Green MegaCampuses. Rich Miller has delivered his annual article containing his top data center industry forecasts, predictions and insights for the year ahead. Of chief concern among the 8 key themes forecasted to define the year is how the AI boom will ripple through the digital infrastructure sector in 2024, impacting the availability of data center space, the supply chain, and factors of pricing, cooling, power and design. Since our industry coverage at DCF throughout the year will frequently refer back to this forecast article, we've decided to enumerate all eight themes throughout several podcast episodes this month.  For this episode, we read down the article's themes 6 through 8: 6.  AI Drives Design Updates for Power and Cooling 7.  Air Permitting at Scale is a Hot Potato 8.  Site Selection Optimizes for Green MegaCampuses "Artificial intelligence is hot," writes Miller. "So hot that the AI boom is creating a resource-constrained world, driving stupendous demand for GPUs, data centers and AI expertise. All three are likely to be in short supply, but none so much as wholesale data center space. This is the trend that dominates our annual forecast." Read the full forecast: The Eight Themes That Will Shape the Data Center Industry in 2024

These are indeed challenging times. How does one stay calm, focused, and effective during difficult times and what does gratitude have to do with it? What is at the core of gratitude? How is it relevant to leadership, and how does one successfully employ it as a method for greater effectiveness during trying times? Join host Dr. Sheryl White, cultural psychologist with the Neighborhood House Association in San Diego, CA; Rich Miller, Senior Pastor of Perfecting Grace Church in San Diego, CA; and Cedric Manley, Founder and CEO of Family Synergy Center in Dallas, TX, as they discuss leadership and the power of gratitude in challenging times.

These are indeed challenging times. How does one stay calm, focused, and effective during difficult times and what does gratitude have to do with it? What is at the core of gratitude? How is it relevant to leadership, and how does one successfully employ it as a method for greater effectiveness during trying times? Join host Dr. Sheryl White, cultural psychologist with the Neighborhood House Association in San Diego, CA; Rich Miller, Senior Pastor of Perfecting Grace Church in San Diego, CA; and Cedric Manley, Founder and CEO of Family Synergy Center in Dallas, TX, as they discuss leadership and the power of gratitude in challenging times.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Richard Miller is a professor of pathology and the Director of the Center for Aging Research at the University of Michigan, as well as a previous guest on The Drive. In this episode, Rich provides an update on the exciting work of the Interventions Testing Program (ITP), an initiative designed to assess potential life-extending interventions in mice. Rich covers the notable successes like rapamycin, 17⍺-estradiol, and acarbose as well as notable failures like nicotinamide riboside, metformin, and resveratrol, providing valuable lessons about the intricacies of the aging process. Rich delves deep into aging biomarkers and aging rate indicators, unraveling crucial insights into the science of geroprotective molecules. Additionally, Rich discusses some surprising successes of recent molecules tested by the ITP and concludes with an optimistic look at future frontiers, including bridging the gap from mice to humans. We discuss: An overview of the Interventions Testing Program (ITP) [3:45]; How the mice used by the ITP are superior for research relative to mouse models used in most research [11:15]; Design of ITP studies, outcomes tested, and metrics of interest [19:00]; The process and challenges of drug formulation for mice [30:00]; Four drugs identified by the ITP that extends the lifespan of mice [36:30]; The success of rapamycin and what it tells us about the biology of aging [43:15]; Other measures of healthspan evaluated by the ITP in stage 2 studies [50:45]; Distinguishing aging rate indicators from biomarkers of aging [57:30]; Aging rate indicators identified through the examination of slow-aging mice [59:15]; Why proteomics are essential to understand changes in the cell [1:12:15]; Unraveling aging rate indicators: dose-effect, duration, and future frontiers [1:21:45]; A closer look at aging rate indicators: bridging the gap from mice to humans [1:27:00]; What do laboratory mice die from? [1:38:45]; Distinguishing between a drug that improves an age-sensitive outcome and a drug that improves all aspects of aging [1:42:00]; The ITP study of 17⍺-estradiol: mechanisms of life extension and surprising sex differences [1:43:30]; Unsuccessful drugs studied by the ITP: resveratrol, metformin, and nicotinamide riboside [1:51:30]; Over-the-counter successes in the ITP: meclizine and astaxanthin [2:01:00]; A senolytic drug, fisetin, fails to extend lifespan [2:07:00]; Can targeting senescent cells slow aging? [2:13:00]; Optimism about future findings [2:16:30]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

For this special episode of the DCF Show podcast, Data Center Frontier's founder and present Editor at Large, Rich Miller, returns for a visit. Tune in to hear Rich engage with the site's daily editors, Matt Vincent and David Chernicoff, in a discussion covering a range of current data center industry news and views. Topics include: Dominion Energy's transmission line expansion in Virginia; Aligned Data Centers' market exit in Maryland over a rejected plan for backup diesel generators; an update on issues surrounding Virginia's proposed Prince William Digital Gateway project; Rich's take on the recent Flexential/Cloudflare outages in Hillsboro, Oregon; and more. Here's a timeline of key points discussed on the podcast: :10 - For those concerned that the inmates might be running the asylum, the doctor is now in: Rich discusses his latest beat as DCF Editor at Large. 1:30 -  We look at the power situation in No. Virginia as explained by one of Rich's latest articles, vis a vis what's going to be required to support growth already in the pipeline, in the form of contracts that Dominion Energy has for power. "Of course, the big issue there is transmission lines," adds Miller. "That's the real constraint on data center power delivery right now. You can build local lines and even substations much more quickly than you can transmission at the regional level. That's really where the bottlenecks are right now." 3:00 - Senior Editor David Chernicoff asks for Rich's take on Aligned Data Centers' recent market exit in Maryland, related to its rejected plan for backup diesel generators. "Is this really going to be the future of how large-scale data center projects are going to have to be approached, with more focus put on dealing with permission to build?" wonders Chernicoff, adding, "And are we going to see a more structured data center lobbying effort on the local level beyond what, say, the DCC [Data Center Coalition] currently does?" 5:19 - In the course of his reponse, Rich says he thinks we'll see just about every data center company realizing the importance of doing their research on the full range of permissions required to build these megascale campuses, which are only getting bigger. 6:12 - Rich adds that he thinks the situation in Maryland illustrates how it's important for data center developers to step back for a strategic discussion regarding depth of planning. "The first thing to know," he points out, "is that Maryand was eager to have the data center industry. They specifically passed incentives that would make them more competitive with Virginia. They saw that Northern Virginia was getting super crowded...and they thought, we've got lots of resources up here in Frederick County, let's see if we can bring some of these folks across the river. And based on that, the Quantum Loophole team found this site." 8:20 - Rich goes on to note how "the key element for a lot of data centers is fiber, and a key component, both strategically and from an investment perspective [in Maryland] is that Quantum Loophole needed to have a connection to the Northern Virginia data center cluster in Ashburn, in Data Center Alley - which is not that far as the crow flies, but to get fiber there, they wound up boring a tunnel underneath the Potomac River, an expensive and time-consuming project that they're in the late stages of now. That's a big investment, and all that was done with the expectation that Maryland wanted data centers." 10:26 - Rich summarizes how the final ruling for Aligned in Maryland "was, effectively, that you can have up to 70 MW but beyond that, you have to follow this other process [where] you're more like a power plant than a data center with backup energy." He adds, "I think one of the issues was [in determining], will all of this capacity ever be turned on all at once? Obviously with diesel generators, that's a lot of emissions. So the air quality boards are wrestling with, on the one hand, having a large company that wants to bring in a lot of investment, a lot of jobs; the flip side is, it's a lot of diesel at a time when we're starting to see the growing effects of climate change, and everybody's trying to think about how we deal with fossil fuel generation. The bottom line is, Aligned pulled out and said, this is just not working. The Governor of Maryland, understanding the issues at stake and the amount of investment that has already been brought there, says that he is working with the legislature to try to 'create some regulatory predictability' for the data center industry. Because it used to be that 70 MW was a lot of capacity, but with the way the industry is going right now, that's not so much." 12:06 - In response to David's reiterated question as to whether the data center industry will now increasingly have to rethink it's whole approach to permitting prior to starting construction, Rich notes, "There's a lot of factors that go into site selection, you're looking at land, fiber, power. The regulatory environment around it, whether there's going to be local resistance, has also become part of the conversation, and rightfully so. One of the things that's definitely going to happen is that data centers have to think hard about their impact on the communities where they're locating, and try to develop sensible policies about how they, for lack of a better term, can be good neighbors, and fit into the communities where they're operating." 14:20 - Taking the discussion back across state lines, Editor in Chief Matt Vincent asks for an update on Rich's thoughts surrounding contentious plans by QTS and Compass Datacenters for a proposed new campus development, dubbed the Prince William Digital Gateway, near a Civil War historic site in Prince William County, Virginia. "This is one of the most unique proposals in the history of the data center industry," explains Miller. "It would be the largest data center project ever proposed. And of course, it's become an enormous political hot potato. It's the first time where we've really seen data centers on the ballot in local elections." 20:41 - After hearing some analysis of the business and political angles in Prince William County, Vincent asks whether Miller thinks the PW Digital Gateway project's future is in doubt, or if it's just that we don't know what's going to happen? 22:50 - Vincent asks Miller for his take on the recent data center outage affecting Flexential and Cloudflare, as written up for DCF by Chernicoff, particularly in the area of incident reports and their usefulness. In the course of responding to a follow-on point by David, Rich says, "I think the question for both levels of providers is, are you delivering on your promises, and what do you need to do to ensure that you can? Let's face it, stuff breaks, stuff happens. The data center industry, I think, is fascinating because people really think about failure modes and what happens, and customers need to do the same." 32:14 - To conclude, Vincent asks for Miller's thoughts on the AI implications of Microsoft's cloud-based supercomputer, running Nvidia H100 GPUs, ranking third on the world's top 500 supercomputers list, as highlighed at the recently ongoing SC23 show in Denver. Here are links to some related DCF articles: -- Dominion: Virginia's Data Center Cluster Could Double in Size -- Dominion Resumes New Connections, But Loudoun Faces Lengthy Power Constraints -- DCF Show: Data Center Diesel Backup Generators In the News -- Cloudflare Outage: There's Plenty Of Blame To Go Around -- Microsoft Unveils Custom-Designed Data Center AI Chips, Racks and Liquid Cooling

George Chacko and Rich Miller of The Bald AV Guys join D and Z to discuss podcasting, the Mets' future, the Jet's present, and much more!

In July, I reviewed Peter's Outlive book here in Ground Truths and hoped I'd be able to interview him about my concerns. Here's that conversation, recorded October 16th. I hope you'll find it informative and stimulating!The AI generated transcript (unedited) below with links to the audio recordingEric Topol (00:01):Peter, it's really great to see you. I haven't been chance to visit since early 2020, and you introduced me to Topo Chico as a great way to get carbonated water. Are you still into those?Peter Attia (00:15):Very much so, yeah. Although I have a different drink today because, well, I don't know why I grabbed for different drinks.Eric Topol (00:22):Yeah, well it's kind of amazing. Distinct from the rest of the waters, fizzy waters. At any rate, since that time, that memorable visit we had, you published an incredible book Outlive, and I think it sold more than a million, well over a million copies, which is amazing. So congratulations.Peter Attia (00:41):Thank you so much.Eric Topol (00:42):It's a great book. And you may have written my review, which I really thought it offers just a great information resource and it must've taken so many years to put it all together.Peter Attia (00:54):Yeah, I think it probably took seven years in total.Eric Topol (00:57):Well, I think it was well worth, and I think it's helping a lot of people. And in fact, I first became aware of it just because these patients were coming into me and saying, well, that's not what Dr. Attia says, or What do you think of Dr. Attia's book ? So that's prompted me to give it a really close read, and I learned a lot from all your work. I thought what we'd start off with, I think you framed it really well with this Medicine, 1.0, 2.0, 3.0 and the shift to the right. So maybe you could explain the concept on that. Sure.Peter Attia (01:34):So Medicine 1.0 is kind of a placeholder for a time before there really was medicine, or at least before, there was sort of a scientific method and an understanding of science and the natural world around us. But of course, from a timescale perspective, it's what dominated all of our civilization. So humans have been around for 250,000 years and until very, very, very recently on that timescale, we didn't really have the tools intellectually to understand science. So we couldn't understand cause and effect. We didn't have a scientific method, let alone capacity to do experiments. And so most of what we did as far as medicine was based on things that we look back at today and think are completely ridiculous. Illness was brought on by the gods or bad humors or things like that. And really then when we start to think about medicine in the way we think about it today, we're really thinking about Medicine 2.0.(02:33):And this is something that was obviously a many, many year transition. Technically I would argue it took place over hundreds of years, beginning with Francis Bacon in the late 17th century or the mid 17th century, but really accelerating in the latter part of the 19th century with germ theory. So we can think about lister, I wrote a little bit about them, and ultimately really a more concrete set of tools including physical tools such as the light microscope, ssid, Muer G writes very elegantly about the importance of the light microscope in the understanding of the cell. And of course a big part of understanding the cell was understanding bacteria, their role in disease. And then we have the advent of antimicrobial agents. So it's this sort of collective set of tools that allow us to basically double without exaggeration human lifespan in a matter of three generations.(03:31):So this is kind of a remarkable trajectory. I think it would be surprising for most people to learn, however, that in this doubling of human lifespan about, well, I would say virtually all of it has come through the reduction of and or elimination of infectious diseases and communicable diseases. And none of that has really come, or very little of that has come by addressing chronic diseases. And so as we've now lived longer by not dying due to the sort of usual infant mortality and infectious disease route, we're instead dying of these chronic diseases. And I think Medicine 2.0 has been largely unsuccessful in that arena with perhaps one exception and that exception is vaccination. So vaccination is in some ways a medicine 3.0 tool because it's a tool of prevention, meaning you treat before a person is sick, whereas most of the success of medicine 2.0 is treat once the patient is ill.(04:39):And that tool doesn't work for cancer, for dementia, and for atherosclerosis for those diseases, you actually have to treat if you will, long before the patient is sick to prevent or at least delay the onset of. So in some ways that is one of the most important pillars of Medicine 3.0, there are several others. So another very important pillar of it is an equal if not greater focus on health span over lifespan where the description and definition of health span are much more rigorous. So the Medicine 2.0 definition of health span is the period of time in which you are free of disability and disease. I kind of reject that definition is not very helpful because I'm as free of disability and disease today at 50 as I was when I was 20, I'm clearly not in as good a shape, I'm not as strong, I'm not as cardio respiratory fit, I'm not as cognitively sharp. So my health span has already declined. But by focusing on metrics of health span in a very detailed way, we're going to get a lot of lifespan benefits for free. And then there's the component of personalizing medicine. So again, it's a term that is rather glib, but it is kind of true. And so we think of evidence-based medicine as the foundation of medicine 2.0, and I think that evidence-informed medicine needs to be the pinnacle or the pillar of medicine 3.0 for reasons I'm sure we'll discuss.Eric Topol (06:10):Yeah. So I buy into the medicine 3.0 concept because we've never fulfilled the fantasy or dream of prevention really as you get to. And the four horsemen that you laid out so well, cancer, neurodegenerative disease, cardiovascular and metabolic dysfunction, all play into that, that we could actually prevent these. One of the questions on that was you shifted to the right better health span, but do you then fall off the cliff that is you have this great health span and you don't have the chronic disease, or do you wind up just basically delaying the chronicity? What are your thoughts about that?Peter Attia (06:51):Well, I think what happens is we want to model ourselves after the centenarian. So centenarians on average are living two decades if not a little bit more than the average person, so slightly more than two decades beyond the average person. And interestingly, they kind of die of the same diseases as the rest of us do. They just have a much more compressed period of morbidity, and they have this phase shift in time for the first brush with disease X. So they're going to die pretty quickly of cancer when cancer sets in, they just get cancer 20 years later. On average, their first brush with cardiovascular disease is also 20 to 25 years later. So if you think about cardiovascular disease in non centenarians, 50% of men, as you probably know, and maybe the audience doesn't, but 50% of men who are going to have a major adverse cardiac event will have it before the age of 65 and 33% of women who will have a major adverse cardiac event in their life will have, so before the age of 65 when we're talking about centenarians, they're into their eighties and nineties when they're having their first major adverse cardiac event.(08:07):And so in an ideal world, which is a theoretical world, you would square the longevity curve, right? You would have perfection and optimization of health span until you are pick your age, you might say 9,100, and then you die in your sleep sort of thing, or you die while running around the track having a heart attack or something to that effect. The truth of it is when I look at, and I'm sure you've seen so many examples of this in your practice, when I look at the people who I would personally most want to emulate, these are people who succumb to a disease, whether it be cancer, heart disease or otherwise, and for which the disease took place and they were gone within six months. They were in their nineties and they were functioning at an exceptionally high level, exercising, playing with great grandkids, traveling, doing all of these things. And then they were diagnosed with pancreatic cancer. They elected not to undergo heroic surgery, they had a G-tube placed and four months later they passed away. And I think we look at that and we say, boy, that's a much better outcome than spending 15 years in a gradual state of decline from the age of 65 to 80, which is the more common finding.Eric Topol (09:24):Yeah. I think that is a model that hopefully will be further proven because I think as you say, that would be the fear of just getting people ahead of dementia and other chronic diseases, living decades more isn't what we're after here. And I think we're totally concordant on that.Peter Attia (09:44):And there's no evidence that it can be done truthfully. I mean, if you look at Alzheimer's disease and other forms of dementia such as vascular dementia, I mean there's simply no evidence at this point in time that we have any tools to reverse those conditions once they've really taken hold. And I think that largely explains why the pharmacologic industry has failed. I mean, I'm not being histrionic when I say that. I mean it. It's been an abject failure to suggest anything otherwise. And again, that suggests that if we're going to do anything about the rising incidences of dementia, it's got to be at identifying the highest risk patients and taking the most significant preventive steps with respect to their metabolic health, exercise, sleep, even aspects of stress management and mental and emotional health. I mean, all of these things factor in, but the time to act on them is long before mild cognitive impairment or M C I sets in.Eric Topol (10:45):Absolutely. One of the things that you hit on so eloquently overall, the whole book is really an aite approach, but the insulin resistance as a critical condition, which is thematic as to getting early to these. And by the way, all four of these major areas are the common threads get to that. And so you have used continuous glucose monitoring. I don't know if you still do and you have centered on this and you're aware that in the medical community there's like a pre-diabetes is a myth, shouldn't be recognized. It's scare mongering. I mean, which is crazy. Can you sort out this because it does seem like insulin resistance and we're going to get into the Glip one drugs is a big deal that's being largely ignored.Peter Attia (11:43):Yeah, it's very interesting. I'm not sure where that's coming from because I actually think the data are quite unambiguous that even beyond or outside of the threshold of type two diabetes, which is currently defined by the hemoglobin A1C historically about 15 years ago and prior, it was defined by the oral glucose tolerance test, but let's just use the modern day definition. So a line was drawn in the sand that said if your hemoglobin A one C is 6.5% or higher, which for most people, but clearly not all people corresponds to an average blood glucose of 140 milligrams per deciliter or higher, you now have this condition called type two diabetes. And presumably anybody with an IQ above about 60 recognizes that indeed your risk of cardiovascular disease, cancer, Alzheimer's disease in addition to your risk of kidney disease and a whole bunch of other things goes up dramatically as a response to that.(12:41):In fact, your all cause mortality is up 40% when you have type two diabetes. Okay, let's put all that aside and assume anybody with half a brain agrees with that. Where I'm not sure I understand any disagreement is if you look at the data for what is the all cause mortality of people with hemoglobin A one C below 6.5, it points to a monotonic decrease in risk as you go down from 6.5 to five. In other words, having an average blood glucose of 100 milligrams per deciliter is better than having an average blood glucose of 110, which is better than 120, which is better than 130. And this is according to all cause mortality data. It's also true that we have better outcomes for people who have, and this is harder to demonstrate, but I think if you look at the type one diabetes data, you see that you have better outcomes with fewer spikes in glucose.(13:45):So in other words, it's not just the average of blood glucose, but it's managing the shape of the glycemic curve. So where I've seen people push back is they will acknowledge if confronted with those data, they'll acknowledge it, but they'll say that, Hey, those data are based on hemoglobin A one C and not C G M, to which I'll say, yeah, that's true. Those data were not captured with C G M. But to me it's a relatively minor leap to say if we know these things based on hemoglobin A one C to be true, it's very likely that they're going to be true based on capturing more accurate data with the continuous glucose monitor. So Eric, I'm not really sure what the hesitation is. If the hesitation is that we don't want payers to cover the cost of C G M for non-diabetics, frankly that's a policy question. I won't wait until that, right? I mean, again, my patients, most of them spend at least 30 days with a C G M non-diabetic patients and they pay out of pocket. So really it's not costing the system anything. And it's really not that expensive relative to the cost of missing out on that information. And for many patients, it becomes a tool that they'll use for more than 30 daysEric Topol (15:00):And they learn certain foods to avoid because of significant spikes and other things likePeter Attia (15:05):That. It's not just the food, although that's the most obvious thing that one learns. But I think what most people find more interesting, and certainly I did and I started wearing A C G M in 2015, what most people learn is the effective sleep, the effective exercise, and the effective stress and how much those things change glucose control. So I was just talking with a patient last week and they were saying, and it's sort of funny because they're telling me this, and of course I already know the answer, but I love hearing them come to this conclusion rather than me telling them. And the patient was saying, wait, what a difference it's making. If I have a bad night of sleep versus a good night of sleep with a really good night of sleep, I can get away with eating X, Y, and Z, and my glucose numbers are well within the parameters we've set for optimal. And if I sleep two hours less, I get home too late, I wake up, something goes wrong, all of that goes out the window.Eric Topol (16:07):Peter Attia (16:07):My Glucose is high overnight, I wake up with high glucose and my glucose tolerance is minimized. And I know for me personally, that was a huge insight that leads me to be very thoughtful about food choices with and without all of the other variables in my life in order.Eric Topol (16:23):Yeah, I think that's actually a project we're working on right now, the multimodal AI interactions between stress, sleep foods and all these things that change glucose spikes. And some people, of course, as you know, they don't spike to anything. And then of course many others, perhaps some majority have some or even very significant spikes. Now, one of the other things I learned, which is not the accepted recommendation, is about protein. You wrote about how one gram of protein per body weight or 130 grams or more. That's one thing I just want to commend you about there is that the medical community doesn't pay enough attention to nutrition. You obviously have zoomed in on this quite a bit, but tell us a little bit more about the protein story. Well,Peter Attia (17:18):I mean I think unfortunately the R D A, the recommended dietary allowance is sort of addressing the wrong question, right? It's a relevant question, it's just not a relevant question today. It was a relevant question in an era of food scarcity, right? So when we think back to the 1940s and the 1950s or during the war when food was not as abundant as it is today, and one was really thinking, what is the minimum effective dose? What's the minimum amount of protein I would need to survive? Yeah, then I think you're closer to that one gram per kilogram of body weight. But if you look at the data more carefully and you ask the question, okay, imagine we're coming from a world that's not resource constrained, which it clearly isn't today. We have unlimited access to energy. It's never been cheaper by energy, I mean food, then the question is, well, what's the optimal amount?(18:19):And you see that the answer is somewhere between 1.4 and two grams per kilo of body weight. So it's potentially twice as much as we've historically told people. And that you might say, well, Peter, that's a really big range, 1.4 to two. How do you anchor in on where it needs to be? And again, I think this is where medicine 3.0 can lend a hand, right? And it depends on a lot of things. It depends on your activity level, it depends on how much you're breaking down muscle on a daily basis, how active you are also depends on how old you are. So the older you get, the more anabolic resistance you have, meaning the more difficult it is to assimilate amino acids in muscle protein synthesis and therefore the more of them you need. It also depends on the quality of those amino acids.(19:07):So if a person is eating a vegetarian diet and they have to get all of their amino acids from plants, they're going to have a harder time reaching the thresholds for leucine, lysine, methionine, which would be some of the most important amino acids, and they're probably going to have to eat more total protein to hit their numbers. So all of these things factor in, and I would say the final thing that we look at is the overall balance of energy in the patient. So you heard me talk about, you probably read that I distinguished between people who are overn, nourished, undernourished, adequately muscled and under muscled. And that creates kind of a two by two that allows you to think about what do we need to do with energy restriction? And if a person is adequately muscled and undernourished, which by the way is a reasonable subset of the population, then you can be a little bit more forgiving on allowing yourself to be at the lower end of that protein intake because the goal is first and foremost to reduce total energy intake. Conversely, if a person is underused and maybe even adequately nourished, you're going to push them to higher levels of protein intake. So it's clearly an art more than it is a science, but the science is the piece that says muscle mass matters tremendously. Frailty is an enormous contributor not just to mortality, but much more importantly to morbidity in an aging population. And therefore everything must be done to minimize frailty and sarcopenia.Eric Topol (20:37):Well, you convinced me that was compelling in the book and I hope my protein intake on the basis of your work there. The other thing, of course, before I get into some questions on the grounds is about you exercise, you're an exercise fanatic. I don't know, are you still exercising three or four hours a day?Peter Attia (21:00):No, I probably average two hours a day.Eric Topol (21:02):That's pretty good. Okay. A little more than the average, I guess though, right?Peter Attia (21:07):Probably yes.Eric Topol (21:08):But it's great that you can do it and that you're committed to it. Now, one of the drugs that is out there as to potentially improving longevity, which has an every animal species tested is rapamycin, which you've acknowledged of course could be trouble because of immune suppression, but it's a candidate drug even we're trying to look at it potentially for long, covid has a lot of good for mitochondrial function as well as potentially for people with activated immune systems. But what do you think about, I guess you take rapamycin and advocate for patients? I do. Yeah.Peter Attia (21:50):I mean, probably 5% of our patients take it. So I wouldn't say that we certainly don't use it in the way we would use, say, lipid lowering drugs where we have a very strong position that's much more clear. But look, rapamycin is a drug I've been studying for probably 10 years now, maybe a little over 10 years actually. And look, I think it's, as you said, it's the most successful molecule that's ever been tested from a Jira protective perspective in the field of science and medicine. So there is no other molecule that has so repeatedly demonstrated a survival advantage across all species. And these are, again, it's important to understand this is all species that span a billion years of evolution. So if you go back and look at the effective mTOR inhibition on yeast, on worms, on flies, and of course more recently on all types of mammals and also important models of mammals. So not just like the B six mouse, but some of the more representative mouse models, of course, Matt Kalin is now testing this in companion dogs. We've got some small primate studies. All of these things are basically showing the exact same effect.(23:14):Couple that with the fact that we have human data using rapa logs, dosed intermittently. So this is a very different dosing schedule than what is used for the immunosuppressive doses, for example, in transplant patients. And we see the opposite now. We see immune enhancement. And that's why in the book I make a point of saying we've historically thought of rapamycin as an immune inhibitor. We're probably better off thinking of it as an immune modulator. So it can be an inhibitor, but it can be an enhancer. And probably one of the most interesting near-term applications for rapamycin might be indeed B-cell enhancement in elderly patients, which is the population. It's already been studied in The 2014 paper with Q Stein led by Joan Manic, demonstrated that just a six or eight week course of intermittent rapamycin followed by a washout was enough to boost immune response to a flu vaccine. So these are very interesting studies, and of course it's unfortunate we're never going to get a hard outcome study of rapamycin in humans because it would take too long and it's never going to bePeter Attia (24:27):Done. So I think the best we're going to get are better and better animal models that more closely approximate humans, for example, in the probably companion dogs would be as good as it's going to get there. The readout of that study will be 2026. And then the best thing we'll expect to see in humans are biomarker studies. Now, the promise today, we don't have really good biomarkers. Rich Miller at the University of Michigan has done some incredible work here identifying a subset of biomarkers from the I T P mice. I would love to see that work replicated in humans and first begin with, Hey, are we even able to measure these well in humans and are we able to perturb them predictably without too much biologic noise? And if we can do those things, then it starts to get very interesting. But Eric, that's my belief as to how we will bridge the gap between where we are now, which is clearly rapamycin works for every creature to where what would be very interesting to know is does it therefore work in humans?Eric Topol (25:28):That'sPeter Attia (25:28):Not a guarantee.Eric Topol (25:29):Yeah, interesting how that plays out because it has real potential. And also, of course, as you well know, it's about a dose story too. It's low doses versus higher doses. And your point about immunomodulation is really important. The next thing I want to ask you about was the total body M R I. As you know, that's become, there's many more startup companies are advocating these and that you could get total body MRIs to prevent. That's something I know you're supportive of, but also obviously there's concerns about rabbit hole incidental findings. What are your thoughts about that?Peter Attia (26:09):Yeah, I mean, I'll take a step back from minute and talk more broadly just about cancer screening because of course, whole body M R I is simply one tool one would use for cancer screening. And this is an area where I've had a real pendulum swing in the last six or seven years. So I think in my training, I trained in surgery, and so going back 15, 20 years, my view was that cancer, aggressive cancer screening was really only giving us lead time bias. And I really wasn't convinced that it was saving lives. But the truth of it is, I didn't really look closely enough at the data. And I think if you look at the data more closely, what you'll realize is that it really does matter how many cancer cells you have in the body when you treat a patient.(26:57):And I think that the burden of disease matters. And I really think that that was the big change in my perspective and the best evidence for this, and I cite two examples in the book, which I think are two of the largest examples, is when you contrast the effect of treating patients with metastatic cancer versus treating patients in the adjuvant setting for the same cancer with the same drug. So just for the listeners to make sense of that, adjuvant therapy is what you give a patient after you've surgically removed the existing tumor and you give it because there are still cells in the body. So when a patient has a colorectal cancer and the surgeon removes the piece of the colon with the cancer and the piece of the lymph nodes that are attached to it, and there's cancer there, but the CT scan demonstrates that at least grossly to the eye, there's no other cancer. So the liver, the lungs, the bones, everything is clean. What do you do with that patient? Well, you know that if you don't treat that patient, 60, 70, 80% of those patients cancer will come back.(28:12):But we know that if you give those patients the FOLFOX regimen and comparable regimens with comparable drugs, at least half of them will be cured. So that's pretty interesting. Now what happens in the case where you go and you take the colon out and now the patient has metastatic disease all over their body? Well, it turns out you're going to give them the exact same chemotherapy, but how many of those patients will survive? Zero. Zero of those patients will survive tragically, every one of those patients will die from their disease today. And so what that tells us, and by the way, we could do the same exercise with breast cancer. So you can take the most common cancers, and it's always the same situation even when you're using the same drugs. We have far better success treating adjuvant in the adjuvant setting than we do in the metastatic setting.(29:06):And I've discussed this with many oncologists, and they all sort of point back to the same argument, which is the more cancer cells you have, the higher the probability that some of those cells are going to find escape mechanisms to the drugs, they're simply going to be able to mutate their way out of the drug. And therefore, when you're treating a billion cells, which is maybe what you're treating in the adjuvant setting, you have a better chance at squashing the cancer than when you're treating tens of billions or hundreds of billions of cells in the metastatic setting. So with all of that said, if the important tool to not succumbing to cancer is reducing the probability of getting cancer, which it clearly is, and we could talk about what are the important steps there beyond the obvious, not smoking. I would say the second most important thing is if you do get cancer, and unfortunately I still believe that you can do everything and still get cancer, there's so much we just don't understand about this disease in a way that we understand so much more about cardiovascular disease.(30:12):But when it comes to cancer, I think Bert Vogelstein was absolutely correct when he said, bad luck just plays an enormous role. And of course, I'm paraphrasing, but that's a very controversial paper he wrote many years ago that I believe is correct. So we have to be able to find it early. Okay, so with all that said, what are the tools we have to detect cancer early? Let's put aside all of them and just talk about the M R I because we can talk about colonoscopy, we can talk about liquid biopsies, which you might want to talk about. But when it comes to the M R I, why has it taken hold as a pan screen of choice? I think there's a couple of reasons, but the most important is it's not invasive and it has no radiation, so there's no physical harm from the test, and that's not true for a lot of other screens, right? A CT scan comes with an enormous amount of radiation. If you're going to do whole body, a whole body CT scan is probably even today, 25 to 30 milli verts, which would be an unacceptable amount of radiation for screening.(31:13):And of course, there are certain types of screening that are very important, but they come with risk like colonoscopy and M r I wouldn't displace that, but we take a slightly more measured approach to it, whereas anybody can go and get this M R I if they're willing to pay. I don't know what the going rate is today. It's one to $2,000 probably for a whole body M R I and obviously that's out of pocket. So let's get to your question now, which is what are the advantages of doing this? What are the blind spots of doing this and what are the down spots? Well, I'll tell you, this is what I say to every one of my patients. Every one of my patients, here's a 10 minute soliloquy that I give on sensitivity, specificity, positive predictive value, negative predictive value, and pretest probability. In fact, I've made a video out of it that I usually have them watch first and then we talk about it so that they really, really get it.(32:01):But what I want everybody to understand is every screening test has an intrinsic sensitivity and specificity, and then your pretest probability is what determines the positive and predictive value. And I say, here's the deal with M R I. It's a very, very high sensitivity test. One of the highest sensitivity tests we have, meaning if you have one of the cancers, it's capable of detecting, so not luminal cancer in an early stage, but if you have one of the cancers that's capable of detecting, it's very likely to detect it. Conversely, it has one of the lowest specificities of any test we can. What that means in English is it's very bad at distinguishing between cancer and non-cancer in terms it's going to cause us a lot of false positives. So then I show them, here is your pretest probability of having cancer, and we have a little model, and I plug in the sensitivity and the specificity. And by the way, we can improve the specificity greatly using diffusion weighted imaging with background subtraction. So I actually don't advocate for off the shelf M R I scanning because they don't use D W I with background subtraction, and therefore the specificity is very low.Peter Attia (33:19):We can really increase the specificity. It's still lower than you would like using diffusion weighted imaging with background subtraction. By the way, that's what makes, for example, multiparametric, M R I for the prostate, such a valuable tool. And then I say, look, the bottom line is that the positive predictive value of this test is still 10 to 20%. That means in English, if there is a positive finding, it is much more likely to not be cancer than to be cancer. And we are going to be on a little bit of a goose chase going after it. And where MRIs are especially weak, is in glandular tissue. This is their Achilles heel. And so is there a likelihood we're going to see a thyroid nodule that is totally irrelevant? Yes. And I say in our experience, I would say one in four patients who undergoes a whole body, M R I, maybe one in five ends up needing to do a follow-up study, like a thyroid ultrasound just to chase something down. Or at a minimum they need to do another scan a year later to follow something that is almost assuredly, nothing like an adrenal adenoma, but just to make sure it's not growing.(34:34):And based on that, Eric, about 10 to 20% of my patients just elect not to do it. They're like, that's not for me. And I say, great, know thyself. If it's for you, I want you to go in eyes wide open. And if it's not for you, I want you to know that you're not doing it and why you're not doing it. But I think that the reality of it is, and where you and I probably share a concern is I think it's very dangerous for patients to go into this without an advocate. And I think, so what I don't fancy is the idea of patients who just go into this without a physician who's there to be able to do with them, what we can do with our patients, which is help them make a very informed decision and just as importantly, walk them through the morass of follow-up should an INCIDENTALOMA show up.Eric Topol (35:30):Yeah, I think the way you prep the patients who go for it is so critical because I have so many patients I know you have who have had to go through all these extra tests, biopsies and whatnot, and came at everything negative, but the anxiety they went through was profound. So that's great. How have you positioned it and maybe in the future, the multi cancer early detection test is, whether it's through methylation or through fragmentation or whatever will be the first test, and then the M r I would be, where is it and what's going on? Because as you pointed out, apley, the number of cells and pre spread is so critical. And once it's already visible on a scan, it's a lot bigger than what you might be able to pick up through the cell-free plasma tumor, D n A. So one last thing I want to ask you about. You didn't write much on the Glip one drugs gyro, and we govi, and they're obviously, I don't know if I've ever seen a drug class like this, Peter, ever. And obviously right now it's not diabetes, it's obesity. But where do you think this is headed? Because as you probably saw, there were people even with early type one diabetes where it got rid of their insulin requirement, small series, but still very intriguing, thin people, right? Where do you see this headed?Peter Attia (37:03):Yeah, I don't think I wrote at all about this in the book truthfully, although I've written and done many podcasts on it since 2020, or probably since 21 was the first time I did a podcast on it. And so I've been following it very closely. And I think like any doctor, I'm constantly being inundated by patient requests to go on it. And it's mostly to manage weight. I mean, there's nobody that's coming to me saying, I'm not happy with my insulin resistance. Please put me on, I want to lose 10 pounds. Please put me on manjaro. By the way, I'm sure you've seen this, but there's now a triple receptor, right? So there's now GLP one, G I P, and then glucagon. And that phase two looked even more dramatic than the phase two and phase three of both tze peptide and semaglutide. It's almost become a Saturday night live skid at this point where at some point there'll be a quad receptor drug that will reduce your weight to zero.(38:08):You'll violate the relativity, you'll violate the principle of conservation of mass at some point. So I won't lie, I do have a couple of concerns, Eric. So we've had a number of patients on these drugs, and in all of our patients, we monitor overnight heart rate and H R V, we do it because it's so easy to do. Every one of our patients has some wearable, they're always wearing a whoop or a Fitbit or something like that. And without exception, every single patient who is on one of these drugs we have yet to see an exception, has an increase in their overnight heart rate of eight to 12 beats per minute.Eric Topol (38:50):I hadn't heard that. I hadn't seen it know about the GI side effects, but hadn't seen the cardiovascular.Peter Attia (38:57):And it goes away when you're off drug,Peter Attia (39:00):Takes a while. It takes a couple of weeks to go away depending on how long you've been on the drug, but your heart rate will return to normal off drug. And I haven't looked in a few months, but I haven't seen an explanation as for why that's the case. But it gives me pause because I can't think of a physiologic scenario that would increase your resting heart rate by 10 beats per minute as a positive thing. Now that doesn't mean it's not a good idea for some people. So in other words, there's clearly benefits to this drug in some populations. But I guess my reaction is if you're a person who just needs to lose 10 pounds, I'm not convinced that the risk is worth it relative to the reward.Eric Topol (39:48):Well, and to your point, there is not just the fact that you're getting this onward effect, at least we would deduce it's untoward, but that these people who are losing more than 10 pounds, losing 50 60, there's no way to get off these drugs that have been mapped out, whatever the effects are. And one I thought you would really zoom in on knowing at least what you've written about is the muscle mass, the fact that there's NIA and bone density loss from these drugs, and especially in people that are taking it long-term. Are you concerned about that?Peter Attia (40:23):We absolutely are. And we don't put patients on them without a DEXA scan, so that if for nothing else, we can demonstrate to them at some point when enough is enough, we're not seeing, and I'm not saying it's not possible, but I'm just saying you probably have to be much more deliberate about it. We're not seeing what I would consider an ideal loss of body weight either. So an ideal loss of body weight is generally regarded as less than 25% of the loss is lean mass, right? So if a person loses 50 pounds less than 12 and a half of those pounds should be lean mass, that would be really, really ideal. When we see people lose 40 pounds, i e 10, of which 10 or less should be lean, we'll easily see it be 50 50.(41:15):That's a very, very common finding. So that person paradoxically, is increasing their percent body fat as they're losing weight. Assuming they started out at 35 or 40% body fat, they're actually getting slightly higher in fat percent. So again, I still think that they're unbalanced. People are getting metabolically healthier when they do this in the short run, but I'd love to see better data. I don't know why I'm not jumping up and down with joy. I know that the rest of the world is so I don't know why I'm not trying to be contrarian about it, but I do have my reservations about their pan use.Eric Topol (42:01):I share those, especially since we don't have a way to get people off if people could and maintain their weight or that. I think because these side effects are notable and even perhaps more than is generally recognized as you're bringing up, the concern here is without a exit ramp, we got a lot of potential lurking trouble there. Well, this has been terrific to review a lot of the create work you did in the book. Some of my questions that I came to when I read it saying, what did you say about this or that? But overall, it's just a great resource for people. It's an inspiration for people to take better care of their health. Maybe they don't want to get into every bit of the things that you've written about, but you certainly covered the bases really well as well as anyone ever has. So it's great work. Peter, thanks so much for joining today.Peter Attia (42:58):Thanks very much for having me, Eric, and thanks for taking the time to read the book and comment on it. Get full access to Ground Truths at erictopol.substack.com/subscribe

Today on the Jayhawker Podcast, we're talking to one of the leaders of the Kansas Defense, Linebacker Rich Miller.  From growing up in Detroit, to his golf game, we'll cover it all!  And Wayne Simien and Greg Gurley will give their impressions of Late Nate at the Phog, and preview Kansas and Oklahoma State. The Jayhawker Podcast is presented by the University of Kansas Health System, the official healthcare provider of KU Athletics, www.kansashealthsystem.com  And by the Hilton President Hotel, the only hotel in the Power and Light District. Just steps from T-Mobile Center. Over 200 rooms and suites to choose from! Call 816-221-9490, or go to www.hilton.comSee omnystudio.com/listener for privacy information.

Today on the Jayhawker Podcast, we're talking to one of the leaders of the Kansas Defense, Linebacker Rich Miller.  From growing up in Detroit, to his golf game, we'll cover it all!  And Wayne Simien and Greg Gurley will give their impressions of Late Nate at the Phog, and preview Kansas and Oklahoma State. The Jayhawker Podcast is presented by the University of Kansas Health System, the official healthcare provider of KU Athletics, www.kansashealthsystem.com  And by the Hilton President Hotel, the only hotel in the Power and Light District. Just steps from T-Mobile Center. Over 200 rooms and suites to choose from! Call 816-221-9490, or go to www.hilton.comSee omnystudio.com/listener for privacy information.

The fundamentals of a Smart Water Triangle include smart controls, BMP's in installation and most importantly the use of AxisDE as a soil conditioner. Rich Miller, co-owner of Miller Landscape in Clearwater, Florida, describes the Smart Water Triangle and his holistic approach to water conversation. He explains ways the State of Florida can bolster their contractor certifications to help create a more professional and knowledgeable work force and discusses his approach in attracting new customers through the promotion of smart irrigation products. Podcast Recorded on September 21, 2023

This episode is an absolute education in the history of steel guitars and slide. Martyn (of Washboard Resonators and Leeds City Stompers fame) and Rich Miller (Rich Slide Guitar) are on with me talking about everything steel guitar and slide playing. We talk about guitar history, how they got into playing these amazing instruments, gear recommendations and slide technique.Cheers to both of the guys for coming on, you can find them both on instagram  and check out some of their crazy skills.Become a Blues Guitar Show Member: https://www.buzzsprout.com/950998/subscribeShoot me a question to cover in the upcoming episodes by emailing ben@thebluesguitarshow.comFollow me on instagram @bluesguitarshowpodcast Make a small donation at 'Buy me a coffee' https://www.buymeacoffee.com/bluesguitarshowSupport the show

Spiritual Warfare: The Kingdom of God Powerfully Advances - Rich Miller, New Life Elder 09 03 23 by New Life of Asheville

Like most protectors, Rich Miller is humble about it all, but this man has given his life serving and protecting the most vulnerable. He spent decades as a distinguished specialist on the NYPD's Emergency Service Unit, including responding to the 9/11 attacks. It was there, on September 12th, Rich raised an American flag on a makeshift piece of rubble. The photo was snapped by a crime scene photographer and it spread, giving hope to a nation reeling. Rich was part 2,500+ high-risk search warrants and entries while on the force, and gave time to help rescue survivors of an earthquake in Haiti. He is a brave man who will push us all forward.  This is the final episode in a 5-part series called Five Marks Summer, celebrating the repackaged publication of Brian's best-selling book, The Five Marks of a Man. Pre-order the newest edition, or the companion Tactical Guide, at briantome.com/fivemarks and get a complimentary poster with each purchase. 

Guest host, Mike Lee. Interviews with Pastors Mike Tallman and Mark Fredenburg of Set Free Northwest program Evergreen, and Rich Miller of Joni and Friends.See omnystudio.com/listener for privacy information.

Kansas Jayhawks Football linebacker position preview led by Craig Young, Rich Miller and Taiwan Berryhill, but it might be Bowling Green LB transfer JB Brown who is the ultimate X-Factor for the unit and Brian Borland's defense. Plus, depth for Lance Leipold's KU team and future names to watch like freshman Logan Brantley. Support Us By Supporting Our Sponsors! Betterhelp This podcast is sponsored by BetterHelp.If you're thinking of starting therapy, give BetterHelp a try. Visit BetterHelp.com/lockedoncollege today to get 10% off your first month.  Gametime Download the Gametime app, create an account, and use code LOCKEDONCOLLEGE for $20 off your first purchase.  LinkedIn LinkedIn Jobs helps you find the qualified candidates you want to talk to, faster. Post your job for free at LinkedIn.com/LOCKEDONCOLLEGE. Terms and conditions apply. eBay Motors For parts that fit, head to eBay Motors and look for the green check. Stay in the game with eBay Guaranteed Fit. eBay Motors dot com. Let's ride. eBay Guaranteed Fit only available to US customers. Eligible items only. Exclusions apply. FanDuel Make Every Moment More. Right now, when you bet on a Super Bowl Winner, you can GET BONUS BETS EVERY TIME THEY WIN IN THE REGULAR SEASON! FanDuel.com/LOCKEDON. FANDUEL DISCLAIMER: 21+ in select states. First online real money wager only. Bonus issued as nonwithdrawable free bets that expires in 14 days. Restrictions apply. See terms at sportsbook.fanduel.com. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, MD, MI, NJ, PA, IL, VA, WV), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 (WY, KS) or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), 1-877-8-HOPENY or text HOPENY (467369) (NY), TN REDLINE 1-800-889-9789 (TN) Learn more about your ad choices. Visit podcastchoices.com/adchoices

Kansas Jayhawks Football linebacker position preview led by Craig Young, Rich Miller and Taiwan Berryhill, but it might be Bowling Green LB transfer JB Brown who is the ultimate X-Factor for the unit and Brian Borland's defense. Plus, depth for Lance Leipold's KU team and future names to watch like freshman Logan Brantley.Support Us By Supporting Our Sponsors!BetterhelpThis podcast is sponsored by BetterHelp.If you're thinking of starting therapy, give BetterHelp a try. Visit BetterHelp.com/lockedoncollege today to get 10% off your first month. GametimeDownload the Gametime app, create an account, and use code LOCKEDONCOLLEGE for $20 off your first purchase. LinkedInLinkedIn Jobs helps you find the qualified candidates you want to talk to, faster. Post your job for free at LinkedIn.com/LOCKEDONCOLLEGE. Terms and conditions apply.eBay MotorsFor parts that fit, head to eBay Motors and look for the green check. Stay in the game with eBay Guaranteed Fit. eBay Motors dot com. Let's ride. eBay Guaranteed Fit only available to US customers. Eligible items only. Exclusions apply.FanDuelMake Every Moment More. Right now, when you bet on a Super Bowl Winner, you can GET BONUS BETS EVERY TIME THEY WIN IN THE REGULAR SEASON! FanDuel.com/LOCKEDON.FANDUEL DISCLAIMER: 21+ in select states. First online real money wager only. Bonus issued as nonwithdrawable free bets that expires in 14 days. Restrictions apply. See terms at sportsbook.fanduel.com. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, MD, MI, NJ, PA, IL, VA, WV), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 (WY, KS) or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), 1-877-8-HOPENY or text HOPENY (467369) (NY), TN REDLINE 1-800-889-9789 (TN) Learn more about your ad choices. Visit podcastchoices.com/adchoices

Spiritual Warfare: The Epic War - Rich Miller, Church Elder 08 06 23 by New Life of Asheville

Rich has been a storyteller since he was a kid. When he was around ten, he started reading to his family after dinner every night. Later in life, he learned that people actually liked having stories acted out for them. He's been on stage in everything from Shakespeare to Damn Yankees to August Osage County, and he starred in the indie feature Acacia Flat, and now he's acting out stories in front of a microphone. Rich created the very popular podcast Audiobook Speakeasy, so he could chat with narrators, coaches, engineers and other industry professionals over drinks. He recently reached the 100th episode.https://www.RichVoiceProductions.comAudiobook narrator Karen Commins owns NarratorsRoadmap.com and hosts Pit Stop. She's joined by fellow audiobook narrator Anne Flosnik as co-host. We hope you'll enjoy the ride!Transcript available here Hosted on Acast. See acast.com/privacy for more information.

Big 12 Media Days were a few weeks ago, but Jason Shepherd interviewed a lot of guys who don't play football for BYU. So, we are focusing on some of the Cougar's opponents. Kansas' Kenny Logan and Rich Miller get defensive, while Cincinnati's coach Scott Satterfield and QB Emory Jones talk about walking into a new situation in the Queen City. Plus, a bonus interview with UCF QB John Rhys Plumlee.

The College Football Experience (@TCEonSGPN) on the Sports Gambling Podcast Network continues its 133 college football 2023 team preview series with the Kansas Jayhawks 2023 season preview. Pick Dundee aka (@TheColbyD) & Patty C (@PattyC831) break down the upcoming 2023 Kansas Jayhawks offense, defense and special teams and key in on what the Jayhawks did in the transfer portal. Will the Kansas Jayhawks be a contender to win the Big 12 Conference in 2023? Could Jalon Daniels be a sleeper Heisman Trophy pick? Plus, Michael Barker aka (@CFBcampustour) joins us to talk about his experiences to Lawrence, Kansas and David Booth Memorial Stadium.Does Lance Leipold and the Kansas Jayhawks returning the 2nd most production in all of college football mean the Jayhawks should be a team to lookout for? Are the Jayhawks set at the QB spot with the return of both Jalon Daniels and Jason Bean? Should the Kansas Jayhawks ground attack be as lethal as ever with the likes of Devin Neal, Daniel Hishaw and Dylan McDuffie? Will the Kansas wide receiving core be improved with the return of Luke Grimm, Lawrence Arnold and Quentin Skinner? Will the tight end position for KU be one of the better in the Big 12 with the likes of Mason Fairchild and Jared Casey? Does the offensive line returning 4 of 5 starters mean the offense should be rolling in 2023?Can the Kansas Jayhawks defense and Brian Borland take the next step in 2023? Will the pass rush be improved in 2023 with the likes of Jereme Robinson, Austin Booker, Patrick Joyner and Hayden Hatcher? Can the linebacking core be the top defensive unit for the Jayhawks since they return Taiwan Berryhill, Rich Miller and Craig Young? Is Cobee Bryant one of the best cornerbacks in America and will the Jayhawks pass defense get any better this year? We talk it all and more on this 2023 Kansas Jayhawks season preview edition of The College Football Experience.=====================================================Discuss with fellow degens on Discord - https://sg.pn/discordSGPN Merch Store - https://sg.pn/storeDownload The Free SGPN App - https://sgpn.appCheck out SGPN.TVSupport us by supporting our partnersCirca Sports - Enter their contests for a chance to win your share of $14 Million - https://www.circasports.com/Underdog Fantasy code SGPN - 100% Deposit Match up to $100 - https://sg.pn/underdogFollow The College Experience & SGPN On Social MediaTwitter - https://twitter.com/TCEonSGPNTwitter - http://www.twitter.com/gamblingpodcastInstagram - http://www.instagram.com/sportsgamblingpodcastTikTok - https://www.tiktok.com/@gamblingpodcastFacebook - http://www.facebook.com/sportsgamblingpodcastYoutube - https://www.youtube.com/@TheCollegeExperienceFollow The Hosts On Social MediaColby Dant - http://www.twitter.com/thecolbydPatty C - https://twitter.com/PattyC831NC Nick - https://twitter.com/NC__NicKWatch the Sports Gambling PodcastYouTube - https://www.sg.pn/YouTubeTwitch - https://www.sg.pn/TwitchRead & Discuss - Join the conversationWebsite - https://www.sportsgamblingpodcast.comSlack - https://sg.pn/slackReddit - https://www.sg.pn/reddit Learn more about your ad choices. Visit podcastchoices.com/adchoices

The College Football Experience (@TCEonSGPN) on the Sports Gambling Podcast Network continues its 133 college football 2023 team preview series with the Kansas Jayhawks 2023 season preview. Pick Dundee aka (@TheColbyD) & Patty C (@PattyC831) break down the upcoming 2023 Kansas Jayhawks offense, defense and special teams and key in on what the Jayhawks did in the transfer portal. Will the Kansas Jayhawks be a contender to win the Big 12 Conference in 2023? Could Jalon Daniels be a sleeper Heisman Trophy pick? Plus, Michael Barker aka (@CFBcampustour) joins us to talk about his experiences to Lawrence, Kansas and David Booth Memorial Stadium. Does Lance Leipold and the Kansas Jayhawks returning the 2nd most production in all of college football mean the Jayhawks should be a team to lookout for? Are the Jayhawks set at the QB spot with the return of both Jalon Daniels and Jason Bean? Should the Kansas Jayhawks ground attack be as lethal as ever with the likes of Devin Neal, Daniel Hishaw and Dylan McDuffie? Will the Kansas wide receiving core be improved with the return of Luke Grimm, Lawrence Arnold and Quentin Skinner? Will the tight end position for KU be one of the better in the Big 12 with the likes of Mason Fairchild and Jared Casey? Does the offensive line returning 4 of 5 starters mean the offense should be rolling in 2023? Can the Kansas Jayhawks defense and Brian Borland take the next step in 2023? Will the pass rush be improved in 2023 with the likes of Jereme Robinson, Austin Booker, Patrick Joyner and Hayden Hatcher? Can the linebacking core be the top defensive unit for the Jayhawks since they return Taiwan Berryhill, Rich Miller and Craig Young? Is Cobee Bryant one of the best cornerbacks in America and will the Jayhawks pass defense get any better this year? We talk it all and more on this 2023 Kansas Jayhawks season preview edition of The College Football Experience. ===================================================== Discuss with fellow degens on Discord - https://sg.pn/discord SGPN Merch Store - https://sg.pn/store Download The Free SGPN App - https://sgpn.app Check out SGPN.TV Support us by supporting our partners Circa Sports - Enter their contests for a chance to win your share of $14 Million - https://www.circasports.com/ Underdog Fantasy code SGPN - 100% Deposit Match up to $100 - https://sg.pn/underdog Follow The College Experience & SGPN On Social Media Twitter - https://twitter.com/TCEonSGPN Twitter - http://www.twitter.com/gamblingpodcast Instagram - http://www.instagram.com/sportsgamblingpodcast TikTok - https://www.tiktok.com/@gamblingpodcast Facebook - http://www.facebook.com/sportsgamblingpodcast Youtube - https://www.youtube.com/@TheCollegeExperience Follow The Hosts On Social Media Colby Dant - http://www.twitter.com/thecolbyd Patty C - https://twitter.com/PattyC831 NC Nick - https://twitter.com/NC__NicK Watch the Sports Gambling Podcast YouTube - https://www.sg.pn/YouTube Twitch - https://www.sg.pn/Twitch Read & Discuss - Join the conversation Website - https://www.sportsgamblingpodcast.com Slack - https://sg.pn/slack Reddit - https://www.sg.pn/reddit Learn more about your ad choices. Visit podcastchoices.com/adchoices

(0:00-18:55) Opening RCST discussing the start of Big 12 Football Media Days live from Dallas (18:56-25:08) Devin Neal live from Big 12 Media Day (25:09-42:53) Voice of the Jayhawks Brian Hanni at Media Day (42:54-53:24) Rich Miller live from Big 12 Media Day (53:25-1:05:09) Producer of 103.7 the Buzz and Neighborhood Watch podcast Josh Nabors (1:05:10-End) Jalon Daniels live from Big 12 Media Day

Coverage from Big 12 Media Days as Mark Rodgers and Cale Gundy discuss a great 2022 season and what to look forward to this season with Kansas LB Rich Miller.See omnystudio.com/listener for privacy information.

Pat sits down with Rich Miller, Jalon Daniels and Lance Leipold of Kansas. See omnystudio.com/listener for privacy information.

Blues in Britain Magazine say Rich's 'Stunning guitar work is second to none' Rich is a true virtuoso guitarist and we get into all things slide and delta blues as well as chatting about gear, turnings and how to approach slide playing.@richslideguitar on Instagram.Become a Blues Guitar Show Member: https://www.buzzsprout.com/950998/subscribeShoot me a question to cover in the upcoming episodes by emailing ben@thebluesguitarshow.comFollow me on instagram @bluesguitarshowpodcast Make a small donation at 'Buy me a coffee' https://www.buymeacoffee.com/bluesguitarshowAcoustic Blues Guitar Course: https://www.udemy.com/share/1086SM/Support the show

What might AI - artificial intelligence - mean for the data center industry? On this week's Data Center Frontier Show, host Rich Miller chats with DCF Senior Editor David Chernicoff, who has been digging into all things AI, including its potential impact on cloud platforms, chip makers, hardware startups, server vendors, and colocation providers. They take a deep dive into the implications of AI for the data center industry. If you are at all interested in AI and data centers, this is the podcast for you.  Here's a timeline of topics David and Rich discuss on the podcast: 1:15 – David shares a bit about his career and "Data Center Journey"  3:45 – "An Interesting Time for Hardware:" Trends driving development of chips and servers.      6:15 – The history of rack density, and the arrival of ChatGPT and generative AI.   11:30 – How AI might be disruptive, and how data and cost factor into its business impact.   17:15 – Echoes of the early days of cloud, and what that tells us about AI's trajectory. 21:30 -- Rich and David discuss the opportunities for colocations, OEMS and the edge.    24:45 -- The Road Ahead: Trends to watch as generative AI evolves, including societal issues  Here's a link to some of David's recent DCF stories on AI and its impact on various sectors within digital infrastructure.   How Intel, AMD and Nvidia are Approaching the AI Arms Race The AI Arms Race: Startups Offer New Technology, Target Niche Markets For Leading Cloud Platforms, AI Presents A Major Opportunity Dell Technologies, HPE Pursue Multiple Paths into Enterprise AI  Did you like this episode? Be sure to subscribe to the Data Center Frontier show so you get future episodes on your app.

DCF Show host Rich Miller chats with Bill Kleyman, a long-time contributor to Data Center Frontier and one of the keynote speakers at the upcoming Data Center World 2023, where he will share insights from the AFCOM State of the Data Center 2023 industry survey. Bill and Rich dive deep into all the hot topics - including the rise of AI, rising rack density, the cloud  capacity crunch and supply chain and nuclear-powered data centers. It's a fun and interesting discussion.  Here's a timeline of topics Bill and Rich discuss on the podcast: 1:45 – State of the Data Center: Key trends in Bill's keynote summarizing the AFCOM survey.  9:45 – Trends in rack density and cooling: Will data centers look more like HPC?     17:00 – Nuclear-powered data centers: Why we're hearing more about this, and the prospects for small modular reactors.   22:15 – Bill and Rich talk supply chain, and the ripple effects on data center delivery.  26:00 – The NIMBY Problem: Why community relations matters for data center companies. 29:15  -- Is there a data center shortage on the horizon.   31:00 -- On the front lines of the AI Boom. Bill's work with Neu.ro. "This is an absolutely critical point for our industry." 37:00 -- AI "hallucinations" and reliability. How do we assess societal impact? 43:00 - How might AI address automation and staffing challenges in the data center industry? 49:15 - The shape of the hybrid cloud: Bill's take on the balance between cloud, colo and on-premises data centers.

In this podcast, I (@aging_scientist) spoke with Dr. Rich Miller about the ins and outs of mouse aging. The topics we discussed, roughly in this order, included the Interventions Testing Program, rapamycin, mecilizine, and other lifespan-extending drugs. We talked about the importance of genetically heterogenous mouse stocks and the issues with fast-aging progeroid mouse models. We also covered his more recent work on aging rate indicators and the difference between classic biomarkers and aging rate indicators. Finally, we talked about the importance of lifespan research, misuse of the word healthspan, and the emerging use of frailty indices in mice. VitaDAO and Kamil Pabis, MSc (the @Aging_Scientist on Twitter) bring this podcast to you.

In this week's episode, we're so lucky to be joined by audiobook narrator and host of 'Audiobook Speakeasy' Rich Miller!Audiobook Speakeasy: https://www.richvoiceproductions.com/audiobook-speakeasyRich's Links:Twitter: @RichMillerVOhttps://www.richvoiceproductions.com/John's Links:Twitter: @JohnYorkUKTikTok: @JohnYorkUKInstagram: @johnny_robukwww.johnyork.co.ukRecommended Clubhouse Room:Audiobooks ClubTHE SUNDAY SCHMOOZE: https://www.clubhouse.com/room/PDpYbNva?utm_campaign=SKIeWZkMqlKA1NslsutpQQ-154266&utm_medium=ch_eventWant to earn more from your audiobook royalties? Check out AMPlify:https://proaudiovoices.com/amplify-audiobook-distribution/Pro Audio Voices:https://proaudiovoices.com/https://proaudiovoices.com/audiobook-marketing-program/https://proaudiovoices.com/access-calls/Support this show http://supporter.acast.com/theaudiobookclub. Hosted on Acast. See acast.com/privacy for more information.

Welcome Back everyone!  Ant and Kate are excited to be back in the podcast world and have been longing to kickstart our new season as we head into 2023.  Our first guest of the season is the talented Rich Miller, who is a recording artist, singer, songwriter and producer extraordinaire.  We talk a lot about his most recent album that released in January, but also touch on many different topics such as dating, song creating, golf and a little neurobiology to spark the mind.  It's great to be back and I hope you enjoy our conversation with the strikingly handsome Rich Miller.Follow us:@exchangestreetconversations@antferneeee@funauntkate@ill.rich

Interview with Rich Miller. He tells us how he got out of religion.Investing Skeptically: 17 year performance of 4 stratagies1- Total US Stock Market2 - Target Date 2015 fund3 - The three legged stool4 - The Polaris Plan

Across Silicon Valley, there are innovations underway that will change the way data centers are cooled. Greg Stover works with technology disruptors to help understand new processor designs and their implications for the design of racks and data halls. DCF Show host Rich Miller talks with Stover, the Global Director of Hi-Tech Development for Vertiv, about trends in processors and how they may accelerate the adoption of liquid cooling.  Greg also discusses the evolution of Vertiv, which he describes as "a $5 billion startup," and what the company sees ahead for  the data center and cloud computing industry in 2023.  Here's a timeline of topics Greg and Rich discuss on the podcast: 1:20 – About Vertiv - "We're a $5 billion startup" - and Greg's role working with tech disruptors.  3:25 – The state of the chip sector, and what it means for the data center sector. 6:30 – What AI adoption means for IT-focused businesses.  .   10:15 – Liquid cooling: What does the transition look like?. 13:45 – Greg's outlook for the future of data center cooling. 16:00  -- The Metaverse question - what might it mean for business and infrastructure.   20:00 -- Edge use cases, and how to plan for edge computing infrastructure. 28:00 -- Greg shares his "Data Center Journey." Be sure to subscribe to the Data Center Frontier show so you get future episodes on your app. We'd love it if you "like" the DCF Show so others can enjoy it as well.

In this episode Gary Mansfield gives a round-up of the episodes of 2022, in a year that gave us Keithy Brymer Jones and his Great British Throw Down co-host Rich Miller, Camille Walala, kennardphillipps, Pure Evil, Gavin Turk, Kate Knight, Rankin, Charlotte Colbert & Jake Chapman, to name but a few.What were your top 5 episodes of 2022?To Support this podcast from as little as £3 per month: www.patreon/ministryofartsFor full line up of confirmed artists go to https://www.ministryofarts.orgEmail: ministryofartsorg@gmail.comSocial Media: @ministryofartsorg Hosted on Acast. See acast.com/privacy for more information.

Rich Miller joins us for a conversation that starts with mythical creatures from the Steely Dan lexicon, jumps to electric Jaguars and ends with Elon Musk's secret monkeys. Then we go down the Luftgekühlt rabbit hole; talking 911Es, Nevada roads, crusty air-cooled Porsche mechanics and the enduring greatness of Risky Business along the way. This is a fun one; grab a cigar and come along for the ride!

Nick opens the episode by explaining why he's done with caveats: Kansas Football is fully capable of winning the Big 12 this season. Then, he's joined by Kansas linebacker Rich Miller who explains why he followed Lance Leipold to Kansas, and why he's not taking time to stop and smell the roses. 

Based on past season's, how many games would be an improvement for the Kansas Jayhawks Football team that they're competitive in? Why is that important for Lance Leipold in year 2 prior to 2023? What's a reasonable expectation of amount of competitive games? Plus KU linebackers discussion with the newly added Eriq Gilyard, Craig Young, Lorenzo McCaskill, and Tristian Fletcher to the unit already featuring Gavin Potter, Rich Miller and Taiwan Berryhill. Support Us By Supporting Our Sponsors! LinkedIn LinkedIn jobs helps you find the candidates you want to talk to, faster. Post your job for free at Linkedin.com/lockedoncollege Terms and conditions apply. Built Bar Built Bar is a protein bar that tastes like a candy bar. Go to builtbar.com and use promo code “LOCKEDON15,” and you'll get 15% off your next order. BetOnline BetOnline.net has you covered this season with more props, odds and lines than ever before. BetOnline – Where The Game Starts! Learn more about your ad choices. Visit podcastchoices.com/adchoices

Based on past season's, how many games would be an improvement for the Kansas Jayhawks Football team that they're competitive in? Why is that important for Lance Leipold in year 2 prior to 2023? What's a reasonable expectation of amount of competitive games? Plus KU linebackers discussion with the newly added Eriq Gilyard, Craig Young, Lorenzo McCaskill, and Tristian Fletcher to the unit already featuring Gavin Potter, Rich Miller and Taiwan Berryhill.Support Us By Supporting Our Sponsors!LinkedInLinkedIn jobs helps you find the candidates you want to talk to, faster. Post your job for free at Linkedin.com/lockedoncollege Terms and conditions apply.Built BarBuilt Bar is a protein bar that tastes like a candy bar. Go to builtbar.com and use promo code “LOCKEDON15,” and you'll get 15% off your next order.BetOnlineBetOnline.net has you covered this season with more props, odds and lines than ever before. BetOnline – Where The Game Starts! Learn more about your ad choices. Visit podcastchoices.com/adchoices

EdgeConneX has built one of unique growth stories in digital infrastructure. An early leader in edge computing, EdgeConneX later began building huge data centers for hyperscale operators. It's a result of following the customers, says Phillip Marangella, the Chief Marketing Officer of EdgeConneX. On today's show, Marangella speaks with host Rich Miller about how edge computing has evolved and where it is headed, how EdgeConneX is seeking to build a diverse workforce, and how the company's 2020 acquisition by EQT Infrastructure has accelerated growth. Here's a timeline of topics Philllip and I discuss on the podcast: 1:00 - The EdgeConneX story: What it does and who it helps. 7:00 - The demand tidal wave: "We're all building as fast as we can." 9:15 - Understanding the Edge: "It's the user experience ... It's not rocket science." 13:00 - Building the worfroce of the future, and why diversity matters at EdgeConneX. 18:00 - Capital matters: How EQT's backing has turbo-charged growth. 21:30 - Digital infrastructure is a global story. If you enjoy this episode, be sure to subscribe to the Data Center Frontier show.

In the conclusion of David's conversation with Rich Miller, the retired CEO of Virtua Health, Rich talks about the two principles that guided his leadership journey and how his team screened for candidates that would fit their culture.