Podcasts about glip

Welcome to the 39th episode in my drug pronunciation series, where I break down Januvia and sitagliptin into syllables, tell you which syllables to emphasize, and share my sources.  The written pronunciations are helpful.  They are below and in the show notes for episode 296 on thepharmacistsvoice.com.   Januvia = jah-NEW-vee-ah Emphasize NEW Source: Medication Guide for Januvia on the FDA's website   Sitagliptin = SIT a GLIP tin Emphasize SIT and GLIP.  GLIP gets the most emphasis. Source: USP Dictionary Online    Thank you for listening to episode 296 of The Pharmacist's Voice ® Podcast.   To read the FULL show notes (including all links), visit https://www.thepharmacistsvoice.com/podcast.  Select episode 296.   If you know someone who needs to learn how to say Januvia and sitagliptin, please share this episode with them.  Subscribe for all future episodes.  This podcast is on all major podcast players and YouTube.  Links to popular podcast players are below. ⬇️   Apple Podcasts   https://apple.co/42yqXOG  Spotify  https://spoti.fi/3qAk3uY  Amazon/Audible  https://adbl.co/43tM45P YouTube https://bit.ly/43Rnrjt   Links from this episode USP Dictionary Online (Subscription-based resource) USP Dictionary's pronunciation guide (Free resource on The American Medical Association's website)  Medication Guide for Januvia on the FDA's website YouTube video about the discovery of Januvia (TEDx Talk) The Pharmacist's Voice Podcast Episode 294, Pronunciation Series Episode 38 (Yasmin) The Pharmacist's Voice Podcast Episode 292, Pronunciation Series Episode 37 (Xanax, alprazolam) The Pharmacist's Voice Podcast Episode 290, Pronunciation Series Episode 36 (quetiapine)  The Pharmacist's Voice Podcast Episode 287, pronunciation series ep 35 (bupropion) The Pharmacist's Voice Podcast Episode 285, pronunciation series ep 34 (fentanyl) The Pharmacist's Voice Podcast Ep 281, Pronunciation Series Ep 33 levothyroxine (Synthroid) The Pharmacist's Voice ® Podcast Ep 278, Pronunciation Series Ep 32 ondansetron (Zofran) The Pharmacist's Voice ® Podcast Episode 276, pronunciation series episode 31 (tocilizumab-aazg) The Pharmacist's Voice ® Podcast Episode 274, pronunciation series episode 30 (citalopram and escitalopram) The Pharmacist's Voice ® Podcast Episode 272, pronunciation series episode 29 (losartan) The Pharmacist's Voice Podcast Episode 269, pronunciation series episode 28 (tirzepatide) The Pharmacist's Voice Podcast Episode 267, pronunciation series episode 27 (atorvastatin)  The Pharmacist's Voice Podcast Episode 265, pronunciation series episode 26 (omeprazole) The Pharmacist's Voice Podcast Episode 263, pronunciation series episode 25 (PDE-5 inhibitors) The Pharmacist's Voice Podcast Episode 259, pronunciation series episode 24 (ketorolac) The Pharmacist's Voice ® Podcast episode 254, pronunciation series episode 23 (Paxlovid) The Pharmacist's Voice ® Podcast episode 250, pronunciation series episode 22 (metformin/Glucophage) The Pharmacist's Voice Podcast ® episode 245, pronunciation series episode 21 (naltrexone/Vivitrol) The Pharmacist's Voice ® Podcast episode 240, pronunciation series episode 20 (levalbuterol) The Pharmacist's Voice ® Podcast episode 236, pronunciation series episode 19 (phentermine)  The Pharmacist's Voice ® Podcast episode 228, pronunciation series episode 18 (ezetimibe) The Pharmacist's Voice ® Podcast episode 219, pronunciation series episode 17 (semaglutide) The Pharmacist's Voice ® Podcast episode 215, pronunciation series episode 16 (mifepristone and misoprostol) The Pharmacist's Voice ® Podcast episode 211, pronunciation series episode 15 (Humira®) The Pharmacist's Voice ® Podcast episode 202, pronunciation series episode 14 (SMZ-TMP) The Pharmacist's Voice ® Podcast episode 198, pronunciation series episode 13 (carisoprodol) The Pharmacist's Voice ® Podcast episode 194, pronunciation series episode 12 (tianeptine) The Pharmacist's Voice ® Podcast episode 188, pronunciation series episode 11 (insulin icodec)  The Pharmacist's Voice ® Podcast episode 184, pronunciation series episode 10 (phenytoin and isotretinoin) The Pharmacist's Voice ® Podcast episode 180, pronunciation series episode 9 Apretude® (cabotegravir) The Pharmacist's Voice ® Podcast episode 177, pronunciation series episode 8 (metoprolol)  The Pharmacist's Voice ® Podcast episode 164, pronunciation series episode 7 (levetiracetam) The Pharmacist's Voice ® Podcast episode 159, pronunciation series episode 6 (talimogene laherparepvec or T-VEC)  The Pharmacist's Voice ® Podcast episode 155, pronunciation series episode 5 Trulicity® (dulaglutide)  The Pharmacist's Voice ® Podcast episode 148, pronunciation series episode 4 Besponsa® (inotuzumab ozogamicin) The Pharmacist's Voice ® Podcast episode 142, pronunciation series episode 3 Zolmitriptan and Zokinvy The Pharmacist's Voice ® Podcast episode 138, pronunciation series episode 2 Molnupiravir and Taltz The Pharmacist's Voice ® Podcast episode 134, pronunciation series episode 1 Eszopiclone and Qulipta   Kim's websites and social media links: ✅Business website https://www.thepharmacistsvoice.com ✅The Pharmacist's Voice ® Podcast https://www.thepharmacistsvoice.com/podcast ✅Pronounce Drug Names Like a Pro © Online Course https://www.kimnewlove.com  ✅A Behind-the-scenes look at The Pharmacist's Voice ® Podcast © Online Course https://www.kimnewlove.com  ✅LinkedIn https://www.linkedin.com/in/kimnewlove ✅Facebook https://www.facebook.com/kim.newlove.96 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Explore the glitz and glamour of Dubai with Palle Bo as he unveils the top 7 must-see attractions in this desert metropolis. From the iconic Dubai Fountain to the adrenaline-pumping adventures of a desert safari, this episode covers it all.   Dive deeper into each attraction:  Dubai Fountain  Ski Dubai  The Dubai Mall  Burj Khalifa  Desert Safari  The Palm Jumeirah   

In this special podcast episode, our in-house Gaming experts Shripati Acharya and Gaurav Ranjan (Investments @PrimeVenturePartners) share everything about the ‘Gaming' sector in India. They share deep insights on the current state, the future, game categories and what kind of companies Prime is excited to invest in. Why is Prime bullish about the Gaming Market in India?No. of Gamers in India - 500 Million (50 Crore)No. of paying Gamers in India - 150 Million (15 Crore)Expected size of Market - $3.5 Billion - $4 BillionWatch the full episode to learn more about how today is the best time to be a ‘Gaming' Entrepreneur in India and what kind of startup you should be building:​​0:00 - Evolution and Future of Indian Gaming4:12 - Evolution and Growth of Gaming Market16:58 - Monetization Strategies in Mobile Gaming25:09 - The Future of Gaming Investments34:55 - Building Organic Distribution for Video Games40:48 - Evolution of Web3 Gaming52:53 - Gaming Entrepreneurship Opportunities in IndiaP.S: you'll learn why we invested in our portfolio companies like Hitwicket and Glip. Enjoyed the podcast? Please consider leaving a review on Apple Podcasts and subscribe wherever you are listening to this.Follow Prime Venture Partners:LinkedIn:   / primevp  Twitter:   / primevp_in  This podcast is for you. Do let us know what you like about the podcast, what you don't like, the guests you'd like to have on the podcast and the topics you'd like us to cover in future episodes.Please share your feedback here: https://primevp.in/podcastfeedback

Efter flere måneder med hvad der føles som konstante tømmermænd, viser det sig til kommunikationsmedarbejder og tidligere model Gertrud Hegelunds 20-ugers scanning, at der mangler en arterie i navlesnoren, en såkaldt SUA-graviditet. Gertrud bliver sat i gang to uger før termin, og fødslen forløber godt. Men lille Nord når kun lige at lande på hendes bryst, inden hun pga. massivt blodtab bliver kørt akut til operation. Hun er i chok og tror, at hun skal dø, og først fire timer senere ser hun sin søn rigtigt for første gang. Trods en hård start på moderskabet, hvor Gertrud er afkræftet og føler sig frarøvet den første magiske tid med Nord, formår hun at finde energi til at at komme igennem forløbet. Jordemoder Camilla Brinch er med til at besvare spørgsmål.

Efter flere måneder med hvad der føles som konstante tømmermænd, viser det sig til kommunikationsmedarbejder og tidligere model Gertrud Hegelunds 20-ugers scanning, at der mangler en arterie i navlesnoren, en såkaldt SUA-graviditet. Gertrud bliver sat i gang to uger før termin, og fødslen forløber godt. Men lille Nord når kun lige at lande på hendes bryst, inden hun pga. massivt blodtab bliver kørt akut til operation. Hun er i chok og tror, at hun skal dø, og først fire timer senere ser hun sin søn rigtigt for første gang. Trods en hård start på moderskabet, hvor Gertrud er afkræftet og føler sig frarøvet den første magiske tid med Nord, formår hun at finde energi til at at komme igennem forløbet. Jordemoder Camilla Brinch er med til at besvare spørgsmål.

In July, I reviewed Peter's Outlive book here in Ground Truths and hoped I'd be able to interview him about my concerns. Here's that conversation, recorded October 16th. I hope you'll find it informative and stimulating!The AI generated transcript (unedited) below with links to the audio recordingEric Topol (00:01):Peter, it's really great to see you. I haven't been chance to visit since early 2020, and you introduced me to Topo Chico as a great way to get carbonated water. Are you still into those?Peter Attia (00:15):Very much so, yeah. Although I have a different drink today because, well, I don't know why I grabbed for different drinks.Eric Topol (00:22):Yeah, well it's kind of amazing. Distinct from the rest of the waters, fizzy waters. At any rate, since that time, that memorable visit we had, you published an incredible book Outlive, and I think it sold more than a million, well over a million copies, which is amazing. So congratulations.Peter Attia (00:41):Thank you so much.Eric Topol (00:42):It's a great book. And you may have written my review, which I really thought it offers just a great information resource and it must've taken so many years to put it all together.Peter Attia (00:54):Yeah, I think it probably took seven years in total.Eric Topol (00:57):Well, I think it was well worth, and I think it's helping a lot of people. And in fact, I first became aware of it just because these patients were coming into me and saying, well, that's not what Dr. Attia says, or What do you think of Dr. Attia's book ? So that's prompted me to give it a really close read, and I learned a lot from all your work. I thought what we'd start off with, I think you framed it really well with this Medicine, 1.0, 2.0, 3.0 and the shift to the right. So maybe you could explain the concept on that. Sure.Peter Attia (01:34):So Medicine 1.0 is kind of a placeholder for a time before there really was medicine, or at least before, there was sort of a scientific method and an understanding of science and the natural world around us. But of course, from a timescale perspective, it's what dominated all of our civilization. So humans have been around for 250,000 years and until very, very, very recently on that timescale, we didn't really have the tools intellectually to understand science. So we couldn't understand cause and effect. We didn't have a scientific method, let alone capacity to do experiments. And so most of what we did as far as medicine was based on things that we look back at today and think are completely ridiculous. Illness was brought on by the gods or bad humors or things like that. And really then when we start to think about medicine in the way we think about it today, we're really thinking about Medicine 2.0.(02:33):And this is something that was obviously a many, many year transition. Technically I would argue it took place over hundreds of years, beginning with Francis Bacon in the late 17th century or the mid 17th century, but really accelerating in the latter part of the 19th century with germ theory. So we can think about lister, I wrote a little bit about them, and ultimately really a more concrete set of tools including physical tools such as the light microscope, ssid, Muer G writes very elegantly about the importance of the light microscope in the understanding of the cell. And of course a big part of understanding the cell was understanding bacteria, their role in disease. And then we have the advent of antimicrobial agents. So it's this sort of collective set of tools that allow us to basically double without exaggeration human lifespan in a matter of three generations.(03:31):So this is kind of a remarkable trajectory. I think it would be surprising for most people to learn, however, that in this doubling of human lifespan about, well, I would say virtually all of it has come through the reduction of and or elimination of infectious diseases and communicable diseases. And none of that has really come, or very little of that has come by addressing chronic diseases. And so as we've now lived longer by not dying due to the sort of usual infant mortality and infectious disease route, we're instead dying of these chronic diseases. And I think Medicine 2.0 has been largely unsuccessful in that arena with perhaps one exception and that exception is vaccination. So vaccination is in some ways a medicine 3.0 tool because it's a tool of prevention, meaning you treat before a person is sick, whereas most of the success of medicine 2.0 is treat once the patient is ill.(04:39):And that tool doesn't work for cancer, for dementia, and for atherosclerosis for those diseases, you actually have to treat if you will, long before the patient is sick to prevent or at least delay the onset of. So in some ways that is one of the most important pillars of Medicine 3.0, there are several others. So another very important pillar of it is an equal if not greater focus on health span over lifespan where the description and definition of health span are much more rigorous. So the Medicine 2.0 definition of health span is the period of time in which you are free of disability and disease. I kind of reject that definition is not very helpful because I'm as free of disability and disease today at 50 as I was when I was 20, I'm clearly not in as good a shape, I'm not as strong, I'm not as cardio respiratory fit, I'm not as cognitively sharp. So my health span has already declined. But by focusing on metrics of health span in a very detailed way, we're going to get a lot of lifespan benefits for free. And then there's the component of personalizing medicine. So again, it's a term that is rather glib, but it is kind of true. And so we think of evidence-based medicine as the foundation of medicine 2.0, and I think that evidence-informed medicine needs to be the pinnacle or the pillar of medicine 3.0 for reasons I'm sure we'll discuss.Eric Topol (06:10):Yeah. So I buy into the medicine 3.0 concept because we've never fulfilled the fantasy or dream of prevention really as you get to. And the four horsemen that you laid out so well, cancer, neurodegenerative disease, cardiovascular and metabolic dysfunction, all play into that, that we could actually prevent these. One of the questions on that was you shifted to the right better health span, but do you then fall off the cliff that is you have this great health span and you don't have the chronic disease, or do you wind up just basically delaying the chronicity? What are your thoughts about that?Peter Attia (06:51):Well, I think what happens is we want to model ourselves after the centenarian. So centenarians on average are living two decades if not a little bit more than the average person, so slightly more than two decades beyond the average person. And interestingly, they kind of die of the same diseases as the rest of us do. They just have a much more compressed period of morbidity, and they have this phase shift in time for the first brush with disease X. So they're going to die pretty quickly of cancer when cancer sets in, they just get cancer 20 years later. On average, their first brush with cardiovascular disease is also 20 to 25 years later. So if you think about cardiovascular disease in non centenarians, 50% of men, as you probably know, and maybe the audience doesn't, but 50% of men who are going to have a major adverse cardiac event will have it before the age of 65 and 33% of women who will have a major adverse cardiac event in their life will have, so before the age of 65 when we're talking about centenarians, they're into their eighties and nineties when they're having their first major adverse cardiac event.(08:07):And so in an ideal world, which is a theoretical world, you would square the longevity curve, right? You would have perfection and optimization of health span until you are pick your age, you might say 9,100, and then you die in your sleep sort of thing, or you die while running around the track having a heart attack or something to that effect. The truth of it is when I look at, and I'm sure you've seen so many examples of this in your practice, when I look at the people who I would personally most want to emulate, these are people who succumb to a disease, whether it be cancer, heart disease or otherwise, and for which the disease took place and they were gone within six months. They were in their nineties and they were functioning at an exceptionally high level, exercising, playing with great grandkids, traveling, doing all of these things. And then they were diagnosed with pancreatic cancer. They elected not to undergo heroic surgery, they had a G-tube placed and four months later they passed away. And I think we look at that and we say, boy, that's a much better outcome than spending 15 years in a gradual state of decline from the age of 65 to 80, which is the more common finding.Eric Topol (09:24):Yeah. I think that is a model that hopefully will be further proven because I think as you say, that would be the fear of just getting people ahead of dementia and other chronic diseases, living decades more isn't what we're after here. And I think we're totally concordant on that.Peter Attia (09:44):And there's no evidence that it can be done truthfully. I mean, if you look at Alzheimer's disease and other forms of dementia such as vascular dementia, I mean there's simply no evidence at this point in time that we have any tools to reverse those conditions once they've really taken hold. And I think that largely explains why the pharmacologic industry has failed. I mean, I'm not being histrionic when I say that. I mean it. It's been an abject failure to suggest anything otherwise. And again, that suggests that if we're going to do anything about the rising incidences of dementia, it's got to be at identifying the highest risk patients and taking the most significant preventive steps with respect to their metabolic health, exercise, sleep, even aspects of stress management and mental and emotional health. I mean, all of these things factor in, but the time to act on them is long before mild cognitive impairment or M C I sets in.Eric Topol (10:45):Absolutely. One of the things that you hit on so eloquently overall, the whole book is really an aite approach, but the insulin resistance as a critical condition, which is thematic as to getting early to these. And by the way, all four of these major areas are the common threads get to that. And so you have used continuous glucose monitoring. I don't know if you still do and you have centered on this and you're aware that in the medical community there's like a pre-diabetes is a myth, shouldn't be recognized. It's scare mongering. I mean, which is crazy. Can you sort out this because it does seem like insulin resistance and we're going to get into the Glip one drugs is a big deal that's being largely ignored.Peter Attia (11:43):Yeah, it's very interesting. I'm not sure where that's coming from because I actually think the data are quite unambiguous that even beyond or outside of the threshold of type two diabetes, which is currently defined by the hemoglobin A1C historically about 15 years ago and prior, it was defined by the oral glucose tolerance test, but let's just use the modern day definition. So a line was drawn in the sand that said if your hemoglobin A one C is 6.5% or higher, which for most people, but clearly not all people corresponds to an average blood glucose of 140 milligrams per deciliter or higher, you now have this condition called type two diabetes. And presumably anybody with an IQ above about 60 recognizes that indeed your risk of cardiovascular disease, cancer, Alzheimer's disease in addition to your risk of kidney disease and a whole bunch of other things goes up dramatically as a response to that.(12:41):In fact, your all cause mortality is up 40% when you have type two diabetes. Okay, let's put all that aside and assume anybody with half a brain agrees with that. Where I'm not sure I understand any disagreement is if you look at the data for what is the all cause mortality of people with hemoglobin A one C below 6.5, it points to a monotonic decrease in risk as you go down from 6.5 to five. In other words, having an average blood glucose of 100 milligrams per deciliter is better than having an average blood glucose of 110, which is better than 120, which is better than 130. And this is according to all cause mortality data. It's also true that we have better outcomes for people who have, and this is harder to demonstrate, but I think if you look at the type one diabetes data, you see that you have better outcomes with fewer spikes in glucose.(13:45):So in other words, it's not just the average of blood glucose, but it's managing the shape of the glycemic curve. So where I've seen people push back is they will acknowledge if confronted with those data, they'll acknowledge it, but they'll say that, Hey, those data are based on hemoglobin A one C and not C G M, to which I'll say, yeah, that's true. Those data were not captured with C G M. But to me it's a relatively minor leap to say if we know these things based on hemoglobin A one C to be true, it's very likely that they're going to be true based on capturing more accurate data with the continuous glucose monitor. So Eric, I'm not really sure what the hesitation is. If the hesitation is that we don't want payers to cover the cost of C G M for non-diabetics, frankly that's a policy question. I won't wait until that, right? I mean, again, my patients, most of them spend at least 30 days with a C G M non-diabetic patients and they pay out of pocket. So really it's not costing the system anything. And it's really not that expensive relative to the cost of missing out on that information. And for many patients, it becomes a tool that they'll use for more than 30 daysEric Topol (15:00):And they learn certain foods to avoid because of significant spikes and other things likePeter Attia (15:05):That. It's not just the food, although that's the most obvious thing that one learns. But I think what most people find more interesting, and certainly I did and I started wearing A C G M in 2015, what most people learn is the effective sleep, the effective exercise, and the effective stress and how much those things change glucose control. So I was just talking with a patient last week and they were saying, and it's sort of funny because they're telling me this, and of course I already know the answer, but I love hearing them come to this conclusion rather than me telling them. And the patient was saying, wait, what a difference it's making. If I have a bad night of sleep versus a good night of sleep with a really good night of sleep, I can get away with eating X, Y, and Z, and my glucose numbers are well within the parameters we've set for optimal. And if I sleep two hours less, I get home too late, I wake up, something goes wrong, all of that goes out the window.Eric Topol (16:07):Peter Attia (16:07):My Glucose is high overnight, I wake up with high glucose and my glucose tolerance is minimized. And I know for me personally, that was a huge insight that leads me to be very thoughtful about food choices with and without all of the other variables in my life in order.Eric Topol (16:23):Yeah, I think that's actually a project we're working on right now, the multimodal AI interactions between stress, sleep foods and all these things that change glucose spikes. And some people, of course, as you know, they don't spike to anything. And then of course many others, perhaps some majority have some or even very significant spikes. Now, one of the other things I learned, which is not the accepted recommendation, is about protein. You wrote about how one gram of protein per body weight or 130 grams or more. That's one thing I just want to commend you about there is that the medical community doesn't pay enough attention to nutrition. You obviously have zoomed in on this quite a bit, but tell us a little bit more about the protein story. Well,Peter Attia (17:18):I mean I think unfortunately the R D A, the recommended dietary allowance is sort of addressing the wrong question, right? It's a relevant question, it's just not a relevant question today. It was a relevant question in an era of food scarcity, right? So when we think back to the 1940s and the 1950s or during the war when food was not as abundant as it is today, and one was really thinking, what is the minimum effective dose? What's the minimum amount of protein I would need to survive? Yeah, then I think you're closer to that one gram per kilogram of body weight. But if you look at the data more carefully and you ask the question, okay, imagine we're coming from a world that's not resource constrained, which it clearly isn't today. We have unlimited access to energy. It's never been cheaper by energy, I mean food, then the question is, well, what's the optimal amount?(18:19):And you see that the answer is somewhere between 1.4 and two grams per kilo of body weight. So it's potentially twice as much as we've historically told people. And that you might say, well, Peter, that's a really big range, 1.4 to two. How do you anchor in on where it needs to be? And again, I think this is where medicine 3.0 can lend a hand, right? And it depends on a lot of things. It depends on your activity level, it depends on how much you're breaking down muscle on a daily basis, how active you are also depends on how old you are. So the older you get, the more anabolic resistance you have, meaning the more difficult it is to assimilate amino acids in muscle protein synthesis and therefore the more of them you need. It also depends on the quality of those amino acids.(19:07):So if a person is eating a vegetarian diet and they have to get all of their amino acids from plants, they're going to have a harder time reaching the thresholds for leucine, lysine, methionine, which would be some of the most important amino acids, and they're probably going to have to eat more total protein to hit their numbers. So all of these things factor in, and I would say the final thing that we look at is the overall balance of energy in the patient. So you heard me talk about, you probably read that I distinguished between people who are overn, nourished, undernourished, adequately muscled and under muscled. And that creates kind of a two by two that allows you to think about what do we need to do with energy restriction? And if a person is adequately muscled and undernourished, which by the way is a reasonable subset of the population, then you can be a little bit more forgiving on allowing yourself to be at the lower end of that protein intake because the goal is first and foremost to reduce total energy intake. Conversely, if a person is underused and maybe even adequately nourished, you're going to push them to higher levels of protein intake. So it's clearly an art more than it is a science, but the science is the piece that says muscle mass matters tremendously. Frailty is an enormous contributor not just to mortality, but much more importantly to morbidity in an aging population. And therefore everything must be done to minimize frailty and sarcopenia.Eric Topol (20:37):Well, you convinced me that was compelling in the book and I hope my protein intake on the basis of your work there. The other thing, of course, before I get into some questions on the grounds is about you exercise, you're an exercise fanatic. I don't know, are you still exercising three or four hours a day?Peter Attia (21:00):No, I probably average two hours a day.Eric Topol (21:02):That's pretty good. Okay. A little more than the average, I guess though, right?Peter Attia (21:07):Probably yes.Eric Topol (21:08):But it's great that you can do it and that you're committed to it. Now, one of the drugs that is out there as to potentially improving longevity, which has an every animal species tested is rapamycin, which you've acknowledged of course could be trouble because of immune suppression, but it's a candidate drug even we're trying to look at it potentially for long, covid has a lot of good for mitochondrial function as well as potentially for people with activated immune systems. But what do you think about, I guess you take rapamycin and advocate for patients? I do. Yeah.Peter Attia (21:50):I mean, probably 5% of our patients take it. So I wouldn't say that we certainly don't use it in the way we would use, say, lipid lowering drugs where we have a very strong position that's much more clear. But look, rapamycin is a drug I've been studying for probably 10 years now, maybe a little over 10 years actually. And look, I think it's, as you said, it's the most successful molecule that's ever been tested from a Jira protective perspective in the field of science and medicine. So there is no other molecule that has so repeatedly demonstrated a survival advantage across all species. And these are, again, it's important to understand this is all species that span a billion years of evolution. So if you go back and look at the effective mTOR inhibition on yeast, on worms, on flies, and of course more recently on all types of mammals and also important models of mammals. So not just like the B six mouse, but some of the more representative mouse models, of course, Matt Kalin is now testing this in companion dogs. We've got some small primate studies. All of these things are basically showing the exact same effect.(23:14):Couple that with the fact that we have human data using rapa logs, dosed intermittently. So this is a very different dosing schedule than what is used for the immunosuppressive doses, for example, in transplant patients. And we see the opposite now. We see immune enhancement. And that's why in the book I make a point of saying we've historically thought of rapamycin as an immune inhibitor. We're probably better off thinking of it as an immune modulator. So it can be an inhibitor, but it can be an enhancer. And probably one of the most interesting near-term applications for rapamycin might be indeed B-cell enhancement in elderly patients, which is the population. It's already been studied in The 2014 paper with Q Stein led by Joan Manic, demonstrated that just a six or eight week course of intermittent rapamycin followed by a washout was enough to boost immune response to a flu vaccine. So these are very interesting studies, and of course it's unfortunate we're never going to get a hard outcome study of rapamycin in humans because it would take too long and it's never going to bePeter Attia (24:27):Done. So I think the best we're going to get are better and better animal models that more closely approximate humans, for example, in the probably companion dogs would be as good as it's going to get there. The readout of that study will be 2026. And then the best thing we'll expect to see in humans are biomarker studies. Now, the promise today, we don't have really good biomarkers. Rich Miller at the University of Michigan has done some incredible work here identifying a subset of biomarkers from the I T P mice. I would love to see that work replicated in humans and first begin with, Hey, are we even able to measure these well in humans and are we able to perturb them predictably without too much biologic noise? And if we can do those things, then it starts to get very interesting. But Eric, that's my belief as to how we will bridge the gap between where we are now, which is clearly rapamycin works for every creature to where what would be very interesting to know is does it therefore work in humans?Eric Topol (25:28):That'sPeter Attia (25:28):Not a guarantee.Eric Topol (25:29):Yeah, interesting how that plays out because it has real potential. And also, of course, as you well know, it's about a dose story too. It's low doses versus higher doses. And your point about immunomodulation is really important. The next thing I want to ask you about was the total body M R I. As you know, that's become, there's many more startup companies are advocating these and that you could get total body MRIs to prevent. That's something I know you're supportive of, but also obviously there's concerns about rabbit hole incidental findings. What are your thoughts about that?Peter Attia (26:09):Yeah, I mean, I'll take a step back from minute and talk more broadly just about cancer screening because of course, whole body M R I is simply one tool one would use for cancer screening. And this is an area where I've had a real pendulum swing in the last six or seven years. So I think in my training, I trained in surgery, and so going back 15, 20 years, my view was that cancer, aggressive cancer screening was really only giving us lead time bias. And I really wasn't convinced that it was saving lives. But the truth of it is, I didn't really look closely enough at the data. And I think if you look at the data more closely, what you'll realize is that it really does matter how many cancer cells you have in the body when you treat a patient.(26:57):And I think that the burden of disease matters. And I really think that that was the big change in my perspective and the best evidence for this, and I cite two examples in the book, which I think are two of the largest examples, is when you contrast the effect of treating patients with metastatic cancer versus treating patients in the adjuvant setting for the same cancer with the same drug. So just for the listeners to make sense of that, adjuvant therapy is what you give a patient after you've surgically removed the existing tumor and you give it because there are still cells in the body. So when a patient has a colorectal cancer and the surgeon removes the piece of the colon with the cancer and the piece of the lymph nodes that are attached to it, and there's cancer there, but the CT scan demonstrates that at least grossly to the eye, there's no other cancer. So the liver, the lungs, the bones, everything is clean. What do you do with that patient? Well, you know that if you don't treat that patient, 60, 70, 80% of those patients cancer will come back.(28:12):But we know that if you give those patients the FOLFOX regimen and comparable regimens with comparable drugs, at least half of them will be cured. So that's pretty interesting. Now what happens in the case where you go and you take the colon out and now the patient has metastatic disease all over their body? Well, it turns out you're going to give them the exact same chemotherapy, but how many of those patients will survive? Zero. Zero of those patients will survive tragically, every one of those patients will die from their disease today. And so what that tells us, and by the way, we could do the same exercise with breast cancer. So you can take the most common cancers, and it's always the same situation even when you're using the same drugs. We have far better success treating adjuvant in the adjuvant setting than we do in the metastatic setting.(29:06):And I've discussed this with many oncologists, and they all sort of point back to the same argument, which is the more cancer cells you have, the higher the probability that some of those cells are going to find escape mechanisms to the drugs, they're simply going to be able to mutate their way out of the drug. And therefore, when you're treating a billion cells, which is maybe what you're treating in the adjuvant setting, you have a better chance at squashing the cancer than when you're treating tens of billions or hundreds of billions of cells in the metastatic setting. So with all of that said, if the important tool to not succumbing to cancer is reducing the probability of getting cancer, which it clearly is, and we could talk about what are the important steps there beyond the obvious, not smoking. I would say the second most important thing is if you do get cancer, and unfortunately I still believe that you can do everything and still get cancer, there's so much we just don't understand about this disease in a way that we understand so much more about cardiovascular disease.(30:12):But when it comes to cancer, I think Bert Vogelstein was absolutely correct when he said, bad luck just plays an enormous role. And of course, I'm paraphrasing, but that's a very controversial paper he wrote many years ago that I believe is correct. So we have to be able to find it early. Okay, so with all that said, what are the tools we have to detect cancer early? Let's put aside all of them and just talk about the M R I because we can talk about colonoscopy, we can talk about liquid biopsies, which you might want to talk about. But when it comes to the M R I, why has it taken hold as a pan screen of choice? I think there's a couple of reasons, but the most important is it's not invasive and it has no radiation, so there's no physical harm from the test, and that's not true for a lot of other screens, right? A CT scan comes with an enormous amount of radiation. If you're going to do whole body, a whole body CT scan is probably even today, 25 to 30 milli verts, which would be an unacceptable amount of radiation for screening.(31:13):And of course, there are certain types of screening that are very important, but they come with risk like colonoscopy and M r I wouldn't displace that, but we take a slightly more measured approach to it, whereas anybody can go and get this M R I if they're willing to pay. I don't know what the going rate is today. It's one to $2,000 probably for a whole body M R I and obviously that's out of pocket. So let's get to your question now, which is what are the advantages of doing this? What are the blind spots of doing this and what are the down spots? Well, I'll tell you, this is what I say to every one of my patients. Every one of my patients, here's a 10 minute soliloquy that I give on sensitivity, specificity, positive predictive value, negative predictive value, and pretest probability. In fact, I've made a video out of it that I usually have them watch first and then we talk about it so that they really, really get it.(32:01):But what I want everybody to understand is every screening test has an intrinsic sensitivity and specificity, and then your pretest probability is what determines the positive and predictive value. And I say, here's the deal with M R I. It's a very, very high sensitivity test. One of the highest sensitivity tests we have, meaning if you have one of the cancers, it's capable of detecting, so not luminal cancer in an early stage, but if you have one of the cancers that's capable of detecting, it's very likely to detect it. Conversely, it has one of the lowest specificities of any test we can. What that means in English is it's very bad at distinguishing between cancer and non-cancer in terms it's going to cause us a lot of false positives. So then I show them, here is your pretest probability of having cancer, and we have a little model, and I plug in the sensitivity and the specificity. And by the way, we can improve the specificity greatly using diffusion weighted imaging with background subtraction. So I actually don't advocate for off the shelf M R I scanning because they don't use D W I with background subtraction, and therefore the specificity is very low.Peter Attia (33:19):We can really increase the specificity. It's still lower than you would like using diffusion weighted imaging with background subtraction. By the way, that's what makes, for example, multiparametric, M R I for the prostate, such a valuable tool. And then I say, look, the bottom line is that the positive predictive value of this test is still 10 to 20%. That means in English, if there is a positive finding, it is much more likely to not be cancer than to be cancer. And we are going to be on a little bit of a goose chase going after it. And where MRIs are especially weak, is in glandular tissue. This is their Achilles heel. And so is there a likelihood we're going to see a thyroid nodule that is totally irrelevant? Yes. And I say in our experience, I would say one in four patients who undergoes a whole body, M R I, maybe one in five ends up needing to do a follow-up study, like a thyroid ultrasound just to chase something down. Or at a minimum they need to do another scan a year later to follow something that is almost assuredly, nothing like an adrenal adenoma, but just to make sure it's not growing.(34:34):And based on that, Eric, about 10 to 20% of my patients just elect not to do it. They're like, that's not for me. And I say, great, know thyself. If it's for you, I want you to go in eyes wide open. And if it's not for you, I want you to know that you're not doing it and why you're not doing it. But I think that the reality of it is, and where you and I probably share a concern is I think it's very dangerous for patients to go into this without an advocate. And I think, so what I don't fancy is the idea of patients who just go into this without a physician who's there to be able to do with them, what we can do with our patients, which is help them make a very informed decision and just as importantly, walk them through the morass of follow-up should an INCIDENTALOMA show up.Eric Topol (35:30):Yeah, I think the way you prep the patients who go for it is so critical because I have so many patients I know you have who have had to go through all these extra tests, biopsies and whatnot, and came at everything negative, but the anxiety they went through was profound. So that's great. How have you positioned it and maybe in the future, the multi cancer early detection test is, whether it's through methylation or through fragmentation or whatever will be the first test, and then the M r I would be, where is it and what's going on? Because as you pointed out, apley, the number of cells and pre spread is so critical. And once it's already visible on a scan, it's a lot bigger than what you might be able to pick up through the cell-free plasma tumor, D n A. So one last thing I want to ask you about. You didn't write much on the Glip one drugs gyro, and we govi, and they're obviously, I don't know if I've ever seen a drug class like this, Peter, ever. And obviously right now it's not diabetes, it's obesity. But where do you think this is headed? Because as you probably saw, there were people even with early type one diabetes where it got rid of their insulin requirement, small series, but still very intriguing, thin people, right? Where do you see this headed?Peter Attia (37:03):Yeah, I don't think I wrote at all about this in the book truthfully, although I've written and done many podcasts on it since 2020, or probably since 21 was the first time I did a podcast on it. And so I've been following it very closely. And I think like any doctor, I'm constantly being inundated by patient requests to go on it. And it's mostly to manage weight. I mean, there's nobody that's coming to me saying, I'm not happy with my insulin resistance. Please put me on, I want to lose 10 pounds. Please put me on manjaro. By the way, I'm sure you've seen this, but there's now a triple receptor, right? So there's now GLP one, G I P, and then glucagon. And that phase two looked even more dramatic than the phase two and phase three of both tze peptide and semaglutide. It's almost become a Saturday night live skid at this point where at some point there'll be a quad receptor drug that will reduce your weight to zero.(38:08):You'll violate the relativity, you'll violate the principle of conservation of mass at some point. So I won't lie, I do have a couple of concerns, Eric. So we've had a number of patients on these drugs, and in all of our patients, we monitor overnight heart rate and H R V, we do it because it's so easy to do. Every one of our patients has some wearable, they're always wearing a whoop or a Fitbit or something like that. And without exception, every single patient who is on one of these drugs we have yet to see an exception, has an increase in their overnight heart rate of eight to 12 beats per minute.Eric Topol (38:50):I hadn't heard that. I hadn't seen it know about the GI side effects, but hadn't seen the cardiovascular.Peter Attia (38:57):And it goes away when you're off drug,Peter Attia (39:00):Takes a while. It takes a couple of weeks to go away depending on how long you've been on the drug, but your heart rate will return to normal off drug. And I haven't looked in a few months, but I haven't seen an explanation as for why that's the case. But it gives me pause because I can't think of a physiologic scenario that would increase your resting heart rate by 10 beats per minute as a positive thing. Now that doesn't mean it's not a good idea for some people. So in other words, there's clearly benefits to this drug in some populations. But I guess my reaction is if you're a person who just needs to lose 10 pounds, I'm not convinced that the risk is worth it relative to the reward.Eric Topol (39:48):Well, and to your point, there is not just the fact that you're getting this onward effect, at least we would deduce it's untoward, but that these people who are losing more than 10 pounds, losing 50 60, there's no way to get off these drugs that have been mapped out, whatever the effects are. And one I thought you would really zoom in on knowing at least what you've written about is the muscle mass, the fact that there's NIA and bone density loss from these drugs, and especially in people that are taking it long-term. Are you concerned about that?Peter Attia (40:23):We absolutely are. And we don't put patients on them without a DEXA scan, so that if for nothing else, we can demonstrate to them at some point when enough is enough, we're not seeing, and I'm not saying it's not possible, but I'm just saying you probably have to be much more deliberate about it. We're not seeing what I would consider an ideal loss of body weight either. So an ideal loss of body weight is generally regarded as less than 25% of the loss is lean mass, right? So if a person loses 50 pounds less than 12 and a half of those pounds should be lean mass, that would be really, really ideal. When we see people lose 40 pounds, i e 10, of which 10 or less should be lean, we'll easily see it be 50 50.(41:15):That's a very, very common finding. So that person paradoxically, is increasing their percent body fat as they're losing weight. Assuming they started out at 35 or 40% body fat, they're actually getting slightly higher in fat percent. So again, I still think that they're unbalanced. People are getting metabolically healthier when they do this in the short run, but I'd love to see better data. I don't know why I'm not jumping up and down with joy. I know that the rest of the world is so I don't know why I'm not trying to be contrarian about it, but I do have my reservations about their pan use.Eric Topol (42:01):I share those, especially since we don't have a way to get people off if people could and maintain their weight or that. I think because these side effects are notable and even perhaps more than is generally recognized as you're bringing up, the concern here is without a exit ramp, we got a lot of potential lurking trouble there. Well, this has been terrific to review a lot of the create work you did in the book. Some of my questions that I came to when I read it saying, what did you say about this or that? But overall, it's just a great resource for people. It's an inspiration for people to take better care of their health. Maybe they don't want to get into every bit of the things that you've written about, but you certainly covered the bases really well as well as anyone ever has. So it's great work. Peter, thanks so much for joining today.Peter Attia (42:58):Thanks very much for having me, Eric, and thanks for taking the time to read the book and comment on it. Get full access to Ground Truths at erictopol.substack.com/subscribe

Dagens Erhvervsoverblik: DI-direktør kalder weekendens overenskomstaftale for en af de mest omfangsrige nogensinde. Danskere strømmer mod platforme som Gomore og Airbnb, hvor udlejning af bolig og bil kan skæppe ekstra i kassen i en vanskelig økonomisk tid. Imens går regeringen glip af milliardskat på danskernes pensionsopsparinger.  Dagens vært: Frederik Vincent (frvi@borsen.dk) 

Hello beautiful people we are back with another makings of you! We have the pleasure to introduce Gerald also known as Glip! Gerald is a Columbus Ohio representative. Gerald is a son, brother, grandson, and father with a lot of humor, heart and wisdom to share with us. He shares his upbringing, stories, visions, and morals with us. Gerald is Everythang Culture. Make sure you turn into this episode and don't forget to like, comment, and share.You can find Gerald at: TikTok: @The_GlipYou can find us at:Www.EverythangCulture.comIG/Facebook/Tiktok/Tumblr: EverythangCultureTwitter: EveryTHGCultureSpotify: https://podcasts.apple.com/us/podcast/everythang-culture/id1455598116?i=1000567850501Apple Podcasts: https://podcasts.apple.com/us/podcast/everythang-culture/id1455598116YouTube: https://www.youtube.com/@everythangculturepodcast2791Support this podcast at — https://redcircle.com/everythang-culture-podcast/exclusive-contentSupport this podcast at — https://redcircle.com/everythang-culture-podcast/exclusive-content

Hvordan er det at gå på højskole? Hør elever fra Grundtvigs Højskoles radiohold tale om deres tid på højskolen lige inden deres efterårsophold er forbi

John & Paul putten inspiratie uit het schooltje. Ze leggen hun oor te luister bij collega's en studenten. Maar ze verdiepen zich ook in eten, drinken en zintuigen. --- Send in a voice message: https://anchor.fm/john--paul-hebben-woorden/message

Selvom Danmark scorer højt på internationale rangeringer for social lighed, konkurrenceevne og meget mere, er der ridser i lakken. Vi udklækker nemlig ikke nok kvindelige iværksættere – kun 1,5% af nye investeringer går til kvinder – og vi har stadig ikke løst udfordringen med at få nok kvinder på ledelsesgangene. Vi går dermed glip af en masse kvindelig innovation.Mia Wagner, som er tidligere CEO for Freeway-koncernen, løvinde og stifter af Nordic Female Founders, gæster Small Great Nation-podcasten til en snak om, hvordan vi fremmer iværksætteri, får mere diversitet i virksomhederne og bedre kvindelig repræsentation i toplederpositioner. Vi taler også om, hvordan vi fremmer mere bæredygtige investeringer.Vært: Peter Mogensen, direktør i Kraka og politisk kommentatorMedvært: Anders Dons, Nordisk CEO for DeloitteMedvirkende: Mia Wagner, stifter af Nordic Female Founders og investor i tv-programmet "Løvens hule"

Har du nogensinde siddet med dine veninder og været så opslugt af de tanker du havde i dit hovede, at du slet ikke kunne være nærværende med dem? For så at komme hjem og være frustreret over at du ikke bare kunne være til stede, nyde deres selskab og have det sjovt? Jeg ser dig og jeg forstår hvor frustrerende det er, fordi jeg har selv været der. Men hvad hvis du i stedet kunne tage afsted til dine aftaler med glæde og overskud uden at skulle overtænke alt? Hvis du med lethed bare kunne være til stede og være nærværende? I dagens podcast episode lærer jeg dig hvordan at du kan være mere tilstede i nuet, så du ikke går glip af alle de vigtige øjeblikke i dit liv.

I stiller spørgsmålene, vi giver jer vores tanker og perspektiver, men sjældent et facit. Brevkassen handler mere om en eksplorativ tilgang til jeres spørgsmål, hvor vi vender og drejer de forskellige vinkler. I denne brevkasse-episode snakker vi blandt andet om: At føle man er gået glip af noget før sit forhold Have haft få sexpartnere Når forskellene er store i ens sociale behov At være en ekstrovert i forhold med en introvert Kan ens kæreste ændre sig? Denne episode er sponsoreret af Zetland. I kan tjekke vores link ud her og få en god deal på et abonnement: https://www.zetland.dk/nusnakkerviomdet   Artikel: Rasmus onanerede 15 timer om dagen. Næsten hver anden unge i Danmark føler sig afhængig af porno https://www.zetland.dk/historie/semEQK6l-mo4EYgyB-99ce7 I kan også finde os på Instagram: @nusnakkerviomdet

This paper presents a grounded language-image pretraining (GLIP) model for learning object-level, languageaware, and semantic-rich visual representations. 2021: Liunian Harold Li, Pengchuan Zhang, Haotian Zhang, Jianwei Yang, Chunyuan Li, Yiwu Zhong, Lijuan Wang, Lu Yuan, Lei Zhang, Jenq-Neng Hwang, Kai-Wei Chang, Jianfeng Gao Ranked #1 on Phrase Grounding on Flickr30k Entities Test (using extra training data) https://arxiv.org/pdf/2112.03857v1.pdf

Glip mee backstage en ontdek de tragiek achter Freddies facade. Op het podium stal hij alle harten, maar na de encores werden er ook heel wat gebroken. Schandalig management, eenzaamheid en een hartverscheurende diagnose. Ook dat is rock-‘n-roll. Duik nog één keer in het legendarische leven van de Queen-frontman in deze laatste aflevering van de Nostalgie-podcast Mercury Mysteries.

**Udsendelsen er bragt i samarbejde med Arbejdernes Landsbank og Bookbeat** September er en god måned at læse bøger i, og derfor har Bold & Bøger-drengene kastet sig over et par klassikere, som man ikke må gå glip af. For kan man godt tale om fodboldbøger hver eneste måned uden at have læst nogle af de helt store værker i fodboldlitteraturens historie? Nej, det kan man ikke. Derfor har Sebastian Stanbury og Martin Davidsen hver især læst en klassiker og taler om den her i september-udgaven af Bold & Bøger.

I dagens podcastepisode har jeg taget en snak med læge Imran Rashid om hans nye bog "Mærkbarhed. Hvordan vi mistede følingen med livet – og hvordan vi finder den igen". Jeg synes, at det er en fantastisk og interessant bog, der sætter ord på vigtige ting, som kan være svært at sætte ord på. Men det gør Imran i denne nye bog. Imran Rashid er speciallæge i almenmedicin. Derudover er han iværksætter, forfatter og foredragsholder, og så har han tidligere kæmpet på det danske seniorlandshold i Taekwondo. Imran Rashid udgav i 2017 bogen SLUK, som i april 2019 er blevet fulgt op af bogen OFFLINE, som både er udgivet i Danmark og internationalt. I 2021 har han udgivet bogen Mærkbarhed, som er skrevet på baggrund af hans samtaler med klienter under Corona-krisen, og som viser os vejen til et bedre liv - et mere mærkbart liv. Mærkbarhed - et ord vi kommer til at bruge "Mærkbarhed" er et ord, som jeg tror, at vi vil høre meget mere til i fremtiden. Det handler bl.a. om at være opmærksom på nuet og de små øjeblikke af liv, som ellers glider ud af hænderne på os. Dét at være i nuet er svært for mange af os at praktisere, men Imran omfavner emnet, og hvordan man gør i praksis på en helt særlig og relevant måde. Lyt med til samtalen herunder, hvor vi bl.a. kommer ind på følgende: Hvad mærkbarhed og målbarhed er for noget, og hvorfor målbarhed kan ødelægge vores trivselHvordan Imran så patienter under Coronakrisen, der bogstaveligt talt var visnet pga. isolation og manglende mærkbarhedAt vi skal kunne mærke, at vi er en del af fællesskaber og ikke bare tro, vi er det (og hvorfor sociale medier svarer til at erstatte mad med tyggegummi)At vi ikke kan løse følelsemæssige problemer med intellektet, og hvad det betyder for fx at trøste børnImrans mærkbare øjeblik, da han sad begravet i arbejdet med bogenAt mærkbarhed ikke kun handler om at mærke det positiveParadokset i, at vi er et af verdens lykkeligste lande men samtidig mistrives voldsomt på indersidenHvordan økonomiske interesser stjæler din evne til at være til stede i dit eget livHelt konkrete måder, som Imran anbefaler, at du kan øge din mærkbarhed med hver dag Ting, som nævnes, i podcastepisoden: Imran Rashid i en tidligere podcastepisode om hvorfor du skal gå OFFLINEBøger af Imran RashidsImran Rashids podcast Lægens ordLæs mere om Imran og hans virksomhed herFind ham på Facebook, Instagram og Twitter Hvis du blevet inspireret af denne episode, så tjek også følgende ud: Taknemmelighedsøvelsen "Værdsættelsesmarathon"Skærmfri ferieaktiviteter der stimulerer sanserne og skærper opmærksomhedsevnenBodyscan. Om kropsbevidsthed og om kroppen som vej ind til nuet

I dagens podcastepisode har jeg taget en snak med læge Imran Rashid om hans nye bog "Mærkbarhed. Hvordan vi mistede følingen med livet – og hvordan vi finder den igen". Jeg synes, at det er en fantastisk og interessant bog, der sætter ord på vigtige ting, som kan være svært at sætte ord på. Men det gør Imran i denne nye bog. Imran Rashid er speciallæge i almenmedicin. Derudover er han iværksætter, forfatter og foredragsholder, og så har han tidligere kæmpet på det danske seniorlandshold i Taekwondo. Imran Rashid udgav i 2017 bogen SLUK, som i april 2019 er blevet fulgt op af bogen OFFLINE, som både er udgivet i Danmark og internationalt. I 2021 har han udgivet bogen Mærkbarhed, som er skrevet på baggrund af hans samtaler med klienter under Corona-krisen, og som viser os vejen til et bedre liv - et mere mærkbart liv. Mærkbarhed - et ord vi kommer til at bruge "Mærkbarhed" er et ord, som jeg tror, at vi vil høre meget mere til i fremtiden. Det handler bl.a. om at være opmærksom på nuet og de små øjeblikke af liv, som ellers glider ud af hænderne på os. Dét at være i nuet er svært for mange af os at praktisere, men Imran omfavner emnet, og hvordan man gør i praksis på en helt særlig og relevant måde. Lyt med til samtalen herunder, hvor vi bl.a. kommer ind på følgende: Hvad mærkbarhed og målbarhed er for noget, og hvorfor målbarhed kan ødelægge vores trivselHvordan Imran så patienter under Coronakrisen, der bogstaveligt talt var visnet pga. isolation og manglende mærkbarhedAt vi skal kunne mærke, at vi er en del af fællesskaber og ikke bare tro, vi er det (og hvorfor sociale medier svarer til at erstatte mad med tyggegummi)At vi ikke kan løse følelsemæssige problemer med intellektet, og hvad det betyder for fx at trøste børnImrans mærkbare øjeblik, da han sad begravet i arbejdet med bogenAt mærkbarhed ikke kun handler om at mærke det positiveParadokset i, at vi er et af verdens lykkeligste lande men samtidig mistrives voldsomt på indersidenHvordan økonomiske interesser stjæler din evne til at være til stede i dit eget livHelt konkrete måder, som Imran anbefaler, at du kan øge din mærkbarhed med hver dag Ting, som nævnes, i podcastepisoden: Imran Rashid i en tidligere podcastepisode om hvorfor du skal gå OFFLINEBøger af Imran RashidsImran Rashids podcast Lægens ordLæs mere om Imran og hans virksomhed herFind ham på Facebook, Instagram og Twitter Hvis du blevet inspireret af denne episode, så tjek også følgende ud: Taknemmelighedsøvelsen "Værdsættelsesmarathon"Skærmfri ferieaktiviteter der stimulerer sanserne og skærper opmærksomhedsevnenBodyscan. Om kropsbevidsthed og om kroppen som vej ind til nuet

I denne episode går snakken på forhold. Alle der har været i et, ved at der altid er problemer og udfordringer. Men vi vil dem så gerne! Udover at inddrage vores egne erfaringer, spurgte vi også om jeres erfaringer om hvilke slags forhold I har været i og hvad I lærte af dem - og fik overvældende meget input! Alt det tager vi op i denne anden udgave af ‘den store forholdssnak'. Vi snakker blandt andet om:  Ikke at give ligeså meget energi senere i et forhold som i starten Tvivlen om hvorvidt man er sammen med den rigtige Frygten for at gå glip af sin ungdom Kan man ramme rigtig første gang og kun have en partner i livet? Når man skulle have været venner i stedet for kærester At blive forladt lige inden man flytter sammen Denne episode er sponsoreret af Zetland. I kan tjekke vores link ud her og få en god deal på et abonnement: https://www.zetland.dk/nusnakkerviomdet

The Flash Cut boys are doing a tabletop RPG this episode! Join them for the first episode of “Modern Kirk: The Adventures of Glip Gallion” and meet some interesting characters along the way! WASH YOUR HANDS! WEAR A MASK! Social Media Podcast: -Twitter, Facebook, IG, and Letterboxd: @flashcutpod -Email: flashcutpodcast@gmail.com -PATREON: https://www.patreon.com/flashcutpod Mitchell -Twitter: @stoneciphermr -Instagram: @stonecipherm Val -Twitter/Instagram: @valentebabb -Letterboxd: @lack_val

Frygten for at gå glip af noget kan kobles tæt sammen med vores syn på verden. Hvis du betragter verden som et skræmmende sted, er der en større sandsynlighed for, at du mærker følelsen af mangel ofte i dit liv – eller frygten for mangel. Det nærmest tragikomiske i dét er blot, at netop fokus på mangel konstant vil øge vores følelse af mangel – alene fordi det er mangel, vi fokusere på. I dagens afsnit taler jeg om, hvordan frygten for at gå glip af noget kan have en direkte påvirkning på din økonomi. Og ikke mindst hvordan du kan begynde at ændre dit fokus. Link til podcast afsnit

GODT NYTÅR! Vi skal i dagens program se nærmere på de 8 største øjeblikke på LOUD, som alle gik glip af, da ingen hørte med. Vi skal se på dengang der gik ild i studiet, da Gantimir tog til USA, Dronning Margrethe blev interviewet i GAMEBOYS, da vi gik i luften for tidligt og meget mere! Dette gør vi i et program fyldt med champagne, stjernekastere, sjove hatte og en krukke med MDMA.Vi har gennem hele 2020 forsøgt at finde lykken og sørge for, at det ikke blev det værste år nogensinde. Vi har stadig ikke fundet lykken, men heldigvis har vi stadig et par timer tilbage af året.

Tak Corona fordi vi blev opmærksomme på, hvad vi har manglet denne jul... Har du nogle bestemte ting du SKAL i december måned? Det har vi... som vi ikke fik gjort i år. Øv!

Det går næsten altid galt, når vi' i byen sammen, synger Thomas Helmig i en kærlighedssang. På samme måde har jeg det med at købe ting - at være forbruger. Jeg elsker det, og jeg hader det. Jeg elsker det, når jeg får lykkerusen ved at købe en ny racercykel, mens jeg hader det, når jeg bare skal ud at købe gaver, eller når vi hører, at man skal være en bevidst forbruger. Hvad er dog det? Hvorfor har jeg det sådan? Og har vi som forbrugere et ansvar? Vært: Svend Brinkmann. Gæster: Anne Glad, livsstilsekspert i Kender du Typen? og foredragsholder. John Thøgersen, professor ved Aarhus Universitet ved Institut for Virksomhedsledelse. Tilrettelægger: Christoffer Heide Høyer.

Die leier van COPE, Mosiuoa Lekota, het die Suid-Afrikaanse veiligheidsgroepering en Departement van Binnelandse Sake veroordeel nadat die selfverklaarde profeet, Shepherd Bushiri, en sy vrou, Mary, die land verlaat het sonder hul paspoorte. Die Minister van Binnelandse Sake, Aaron Motsoaledi, verskyn tans voor die parlement om te verduidelik hoe die egpaar daarin kon slaag om na Malawi te vlug. Motsoaledi het vanoggend onthul dat die egpaar elk vyf paspoorte het en dat hul permanente verblyfpermit onreëlmatig is. Die egpaar het die naweek uit die land gevlug nadat hulle verlede week op borgtog van 200-duisend Nsamibiese doller vrygelaat is. Lekota sê die land se Veiligheidsgroepering slaap wanneer hulle moet werk.

Ugentlige nyheder fra Valby Bladet

Ugentlige nyheder fra Østerbro Avis

Ugentlige nyheder fra Brønshøj-Husum Avis

Ugentlige nyheder fra Vesterbro Bladet og Kgs. Enghave Bladet

Ugentlige nyheder fra City Avisen og Amager Bladet

Opsamling af ugens københavnernyheder udvalgt fra Berlingske, Information, Jyllands-Posten og Politiken.

HK JobBørs er HK’s rekrutteringstilbud til dig som medlem - og til dig som arbejdsgiver. Med HK JobBørs matcher vi arbejdsgivernes ønsker og behov til nye medarbejdere med tusindvis af dygtige HK'ere. I podcasten kan du blive klogere på, hvordan du kan bruge HK JobBørs. Ved mikrofonerne er kommunikationskonsulent Hanne Vammen og jobformidler Lone Bjørnkjær. Se mere om HK JobBørs på hk.dk

Nimas producer, Johanne, har fødselsdag og derfor taler han med lytterne om, hvilke mærkedage de misser her i coronatiden. I dette sammendrag taler han med Gert, Jørgen, Raido og Christina

Johanne, der er producer på nattens program, har fødselsdag. Men pga. coronavirussen, må hun holde det på en lidt anderledes måde - derfor spørger Nima i nat lytterne, hvilke mærkedage de har misset eller må holde anderledes pga. corona. Den første lytter er Gert, som er ked af, han ikke længere kan sælge Hus Forbi-aviser. Jørgen skulle have været til 80-års fødselsdag for et par dage siden, men den blev aflyst. Derefter taler Nima med Ina, der føler sig meget ensom og alene i denne coronatid. OG så fortæller hun historien om dengang, hendes hund opdagede, at hun havde brystkræft. Raido har de sidste mange måneder bygget på nogle terapihaver, og åbningen af dem er nu udskudt pga. corona. Vi slutter natten af i selskab med Christina, der ikke længere får sine ugentlige besøg fra kommunen pga. corona.

Episode 58: We spoke with Peter Pezaris, co-founder and CEO of CodeStream. We discuss the process behind selling a company, including how to know when it's time to sell as well as when to leave, the time he and his team spent as part of Y Combinator's Winter 2018 class, and how Peter has kept his founding team intact through four startups. Enjoy! Peter Pezaris, co-founder and CEO of CodeStream, a company helping development teams communicate more efficiently. Peter is a serial entrepreneur with three successful exits under his belt (including Glip, sold to RingCentral and Commissioner.com, sold to CBS), with CodeStream being his fourth startup. Interestingly, Peter has kept his executive/founding team intact throughout the four startups and over two decades (they met as undergrads at Carnegie Mellon). --- Support this podcast: https://anchor.fm/besttechie/support

Mange voksne kan sikkert genkende følelsen af, at man nødigt vil gå glip af noget - heller ikke online. Det ser og oplever vores børn, og det bliver også noget de skal lære at håndtere, når de begynder deres online sociale liv. I denne udgave af Skærmtid kigger vi både på børnene, men også på vores egen opførsel online, når vi taler om og debatterer, angsten for at gå glip af noget.

I dagens udsendelse skal det handle om EU’s projekt #Wifi4EU, der giver kommuner mulighed for at søge om 112.000 kr. fra EU til at opsætte trådløst internet på offentlige arealer. Men mange danske kommuner søger ikke, og dermed går de samlet glip af millioner af kroner. I foråret er det sidste chance - men hvorfor er der ikke flere, der søger pengene? Vi taler desuden med en bulgarsk fagforening om mindsteløn og forsøger at få Skotland til at blive en del af Skandinavien. Medvirkende: Plamen Dimitrov, formand for Sammenslutningen af Uafhængige Fagforeninger i Bulgarien, Tonni Hansen (SF), borgmester på Langeland, Jacob Spildsboel, erhvervs- og udviklingskonsulent fra Stevns, Jette Vindum, projektleder i Vejle Kommune, Lars Peter Mosgaard, IT-chef i Varde, Poul Venø, IT & Digitalisering chef i Herning og Duncan Daillie, medlem af Det Skotske Nationalparti. Værter: Mads Anneberg og Tine Toft

Sommeren er over os og snart er der ferie for de fleste. Men ligesom med juleferien, byder sommerferien på flere fristelser end normalt. Hvordan du reagerer på disse kan have stor betydning for din vægt – og dermed for, hvad der kommer af bekymringer og eventuelt kure efter ferien. Der er to klassiske reaktioner på ferie: giv slip eller gå glip! Men heldigvis findes der en mellemvej. Hvordan den ser ud kan du høre meget mere om i denne episode af “Detox din hjerne”, hvor vi kommer med konkrete tips til, hvordan du kan få mindre mad, men mere nydelse – og endda kan opleve mere af den frihed, der er temaet for ferietiden. Find show notes på www.detoxdinhjerne.dk.

In episode 61 of #TDLS, I sit down with Ron Cani. Ron is the Co-Founder and CEO of GoCrayons. He is also a creative entrepreneur and a visionary from the Philippines. He and his talented creative team is really passionate about turning great ideas into beautiful and interactive websites that serve clients across many countries like US, UK, and Australia. In this episode we talk about: -His design life stories from ground-up - How he was able to turn his passion in building the website into a now over 40 members creative business - A high level overview of what is like to grow up as a creative in a developing country like Philippines - How to find your why on pursuing your creative career - Practical steps on how you can start your creative journey today - And much much more... You can learn more about Go Crayons and Ron by visiting gocrayons.com and let Ron knows if you love this episode by following them @gocrayonsteam. Shownotes Links: Creative Team: gocrayons.com Elementor Resources: elementorresources.com Elementor Resources Page: https://www.facebook.com/elementorresources/ Glip: glip.com Join my slack community of accountable & passionate creatives by visiting jaychristteves.com/community Visit the podcast now at thedesignlifeshow.com to get all the episodes 100% FREE. Have a question in mind? Submit your question to be answered on the podcast. Send your questions (at least 2-minute audio clip) at hi@jaychristteves.com PS: Please don't forget to leave your reviews and/or feedback. It'll help the show reach more people. Huge thanks for the support! PPS: Go and get the podcast it's 100% FREE to download on any of your favorite podcast apps using your Android or IOS phone. Links below for your reference. Apple Podcasts/iTunes: https://goo.gl/b74xuR Google Podcasts: https://goo.gl/GqpQhF SoundCloud: https://goo.gl/UcqHUv Stitcher: https://goo.gl/bVxHs7 TuneIn: https://goo.gl/9MAvpi RadioPublic: https://goo.gl/MY7uiQ

In dieser neuen Reihe nehmen wir euch auf unserer 10 tägigen Reise in der Startup School des Media Lab Bayerns mit. Die Folgen wurden als Facebook Live Stream ausgespielt, weswegen die Tonqualität nicht ganz ideal ist. Dennoch wollen wir euch an praxisnahen Know How auch hier im Podcast teilhaben lassen! Links zu dieser Episode: - Screen Time for iphone or android - Timeular Würfel https://timeular.com/ - Kanban: https://de.wikipedia.org/wiki/Kanban-Tafel - Pomodoro: http://www.tomato.es/ www.tomato-timer.com - Weitere Tools: Clickup, Glip, Trello, Zenkit, Todoist, Wunderlist, Evernote, Google Tasks - Offline-Tools: Hallo Klarheit, Ein gutes Ziel, Passion Planner, Bullet Journal

In dieser neuen Reihe nehmen wir euch auf unserer 10 tägigen Reise in der Startup School des Media Lab Bayerns mit. Die Folgen wurden als Facebook Live Stream ausgespielt, weswegen die Tonqualität nicht ganz ideal ist. Dennoch wollen wir euch an praxisnahen Know How auch hier im Podcast teilhaben lassen! Links zu dieser Episode: - Screen Time for iphone or android - Timeular Würfel https://timeular.com/ - Kanban: https://de.wikipedia.org/wiki/Kanban-Tafel - Pomodoro: http://www.tomato.es/ www.tomato-timer.com - Weitere Tools: Clickup, Glip, Trello, Zenkit, Todoist, Wunderlist, Evernote, Google Tasks - Offline-Tools: Hallo Klarheit, Ein gutes Ziel, Passion Planner, Bullet Journal

Alt for mange danskere går glip af rigtigt mange bonuspoint fordi de vælger de forkerte betalingsmidler. Selvom Danmark er et kreditkort uland, så er det ikke ensbetydende med at man helt skal opgive at bruge de produkter som er på markedet.Som udgangspunkt kan du tjene bonus på alle dine betalinger, som du kan bruge på gratis rejser. Men hvilket kreditkort skal du vælge?Vi ser nærmere på de muligheder, der findes på det danske marked og giver dig gode råd om hvilke kort du skal vælge for både at optimere din pointindtjening og få mest ud af de andre fordele, som følger med visse kort.Artikler omtalt i denne episode:Er der bedring i vente i kreditkort-ulandet DanmarkAlt du bør vide om de nye kreditkortreglerDanskerne får dårligere og dyrere kreditkort end svenskerneAndre interessante links:FinalCall.travelFrequent Traveler Danmark Facebook-gruppe

Dan got a pair of TaoTronics but has a problem with them: https://www.taotronics.com The HomePod is on sale: https://www.theverge.com/good-deals/2018/12/12/18136701/apple-homepod-deal-sale-b-h-photo Qualcomm won a ban on iPhones in China: https://www.macrumors.com/2018/12/13/qualcomm-seeks-iphone-xs-xr-sales-ban-china/ Google's Sundar Pichai testified before Congress and it didn't go all that great: https://www.wired.com/story/congress-sundar-pichai-google-ceo-hearing/ Cyber chief Rudy Giuliani doesn't understand how URLs work in Twitter: https://www.nbcnews.com/tech/tech-news/rudy-giuliani-falsely-blames-twitter-after-typo-points-anti-trump-n944136 Apple may be bringing a subscription service to Apple News: https://www.macrumors.com/2018/12/12/apple-news-subscription-service-spring-2019/ Our thanks to Glip (http://glip.com/rebound) team messaging and collaboration in one digital workspace. Glip's all-in-one task management is a fast and effective to get everyone on the same page. Sign up for a free Glip account by going to glip.com/rebound (http://glip.com/rebound). And our thanks to Stamps.com (http://stamps.com). With Stamps.com you can access all the services of the Post Office right from your desk. Right now, use the code REBOUND to get a 4-week Trial – which includes postage and a digital scale! Go to Stamps.com and click on the Radio Microphone at the TOP of the homepage and type in REBOUND.

John Gruber's iPhone XR review: https://daringfireball.net/2018/10/the_iphone_xr Mike Hurley's iPhone XS vs Pixel 3 photo comparison: https://www.instagram.com/stories/highlights/17861051287295881/ Apple's October 30th event invitations were unique: https://www.macrumors.com/2018/10/18/apple-event-new-york-city/ Tim Cook asks Bloomberg to retract its China chip spying story: https://www.reuters.com/article/us-apple-bloomberg/apple-ceo-urges-bloomberg-to-retract-spy-chip-story-idUSKCN1MT2Z8 Jason Snell talks to Mike Hurley about the story on Upgrade: https://www.relay.fm/upgrade/214 Our thanks to Glip (http://glip.com/rebound) team messaging and collaboration in one digital workspace. Glip's all-in-one task management is a fast and effective to get everyone on the same page. Sign up for a free Glip account by going to glip.com/rebound (http://glip.com/rebound). Our thanks as well to Robinhood, an investing app that lets you buy and sell stocks, ETFS, options, and cryptos, all commission-free. Robinhood is giving listeners of the Rebound a FREE stock like Apple, Ford, or Sprint to help build your portfolio! Sign up at REBOUND .robinhood.com (http://rebound.robinhood.com). And our thanks to the National Security Agency. The National Security Agency plays a big role in protecting us from foreign cyber operations, and you can help! If you work in computer science, networking, programming or electrical engineering, learn more about careers at the National Security Agency by visiting IntelligenceCareers.gov/NSA (http://intelligencecareers.gov/nsa).

So you get ready to make a salad and you rinse the lettuce and carrots and tomatoes under the faucet for a few seconds. Does that really get rid of the pesticides and bacteria? We explore that very important question and you really need to hear the answer. http://www.menshealth.com/how-to-wash-produceDo you understand the difference between pleasure and happiness? It’s an important distinction because the more pleasure you seek, the less happy you become. That’s the contention of Dr Robert Lustig, author of The Hacking of the American Mind: The Science Behind the Corporate Takeover of Our Bodies and Brains https://amzn.to/2yp2xMf. Dr. Lustig sees some troubling developments in our quest for pleasure and I think you’ll be interested in what he has to say. It’s become a cliché to say that great ideas come in the shower. But the fact is – they do! And there is actually a psychological explanation for why that is. We begin this episode with a look at the reason for this common experience. http://mentalfloss.com/article/52586/why-do-our-best-ideas-come-us-showerNobody likes failure – but maybe we should all rethink that. Failure turns out to have a silver lining – and not just in the way that “Every cloud has a silver lining.” Chris Gethard is a pretty successful stand-up comedian who has written a book about failure called Lose Well https://amzn.to/2CpJcgz. Although Chris has had some clearly successful moments (his own HBO special and his own sitcom on Comedy Central for example) he has also had some colossal failures. He joins me to discuss why failure is inevitable and really something to be celebrated on your journey to success.This Week's SponsorsLinkedIn Talent. To find the right person for the job and get $50 off your first job post, go to www.Linkedin.com/somethingSimplisafe. For amazing home security at a great price go to www.simplisafe.com/somethingGlip. Sign up for your FREE GLip account now and support this podcast by going to www.Glip.com/somethingLinkedIn Marketing Solutions. For your free $100 ad credit to launch your first campaign go to www.Linkedin.com/somethingMadison Reed. For 10% off plus free shipping on your first order go to www.Madison-Reed.com/somethingJet.com. For a great online shopping experience like no other go to www.jet.comHotel Tonight. To get $25 off your first eligible booking download the Hotel Tonight app and use the promo code something.

Spending time with annoying and irritating people can be hazardous to your mental health! That’s according to some research from my alma mater, the University of Southern California. I begin this episode with that and how to bulletproof yourself from the negative effects of those most irritating people. https://timesofindia.indiatimes.com/home/science/Annoying-people-can-slow-down-your-brain-Study/articleshow/16765621.cmsWhen you fly on a commercial airplane, I know you have questions about how commercial aviation works – or sometimes DOESN’T work very well. Patrick Smith is a commercial airline pilot and blogger at www.askthepilot.com and author of the book, Cockpit Confidential: Everything You Need to Know About Air Travel https://amzn.to/2CfqIPY. He joins me to answer some of the questions you think about when you are sitting and wondering in your airline seat. Sometimes in winter, you have to stay warm. And as the weather cools off, it is a good time to discuss what’s really important to staying warm in cold weather and how the body reacts to preserve itself when temperatures drop. http://theweek.com/article/index/254754/how-to-keep-warm-outside-5-science-based-tipsWe live in a time when productivity is essential. There is always more to do - but wait! Is striving to do more actually an effective strategy? What if I told you that taking time to unwind, relax and nurture yourself actually makes you MORE productive? You need to hear some important research from Jamie Gruman, professor of Organizational Behavior and a Senior Research Fellow at the University of Guelph in Ontario, Canada. Jamie is author of the book Boost: The Science of Recharging Yourself in an Age of Unrelenting Depends https://amzn.to/2pSD8G0. He joins me to challenge everything you’ve ever thought about productivity and getting more done. And you are really going to like what he has to say.This Week's SponsorsLinkedIn Talent. To find the right person for the job and get $50 off your first job post, go to www.Linkedin.com/somethingSimplisafe. For amazing home security at a great price go to www.simplisafe.com/somethingGlip. Sign up for your FREE GLip account now and support this podcast by going to www.Glip.com/something LinkedIn Marketing Solutions. For your free $100 ad credit to launch your first campaign go to www.Linkedin.com/somethingMadison Reed. For 10% off plus free shipping on your first order go to www.Madison-Reed.com/somethingJet.com. For a great online shopping experience like no other go to www.jet.com Hotel Tonight. To get $25 off your first eligible booking download the Hotel Tonight app and use the promo code something.

Anyone who has ever cooked pasta has thought about using HOT tap water instead of cold to speed up the process. After all, hot tap water takes less time to boil. But is it really a good idea to cook with hot tap water? We begin this episode with a discussion on why it is such a bad idea. https://www.nytimes.com/2008/01/29/health/29real.htmlIt may seem as if it's luck or chance that causes some things catch on and become popular or go viral. But it isn’t luck really. If you’ve ever wondered why some restaurants succeed while others fail or why some books, TV shows or movies do great but others go nowhere, you will want to listen to this segment. Jonah Berger, is a professor at the Wharton School at the University of Pennsylvania and author of the book Contagious: Why Things Catch On https://amzn.to/2IQAn0s. Jonah joins me to explains the science of popularity – and it really is a science. Conventional wisdom is that you should change the oil in your car every 3,000 miles. And it is a great example of just how wrong conventional wisdom is. Now it used to be accurate but not with cars today. Listen as I reveal how often you should REALLY change your oil. http://www.edmunds.com/car-care/stop-changing-your-oil.html?mktcat=maintenance-article&kw=stop+changing+your+oil&mktid=ob61762858&msite=wLogic is sometimes misunderstood. For example, can you be logical AND emotional? (That was always an issue for Mr. Spock on Star Trek). Is there only one logical way to get to a conclusion? How does logic really work? We all need logic and to help you understand it is Eugenia Cheng. She is Scientist in Residence at the School of the Art Institute in Chicago and author of the book The Art of Logic in an Illogical World https://amzn.to/2QHth15. She joins me to explain logic and how you can use logic more effectively in your life.This Week's Sponsorscare/of. For 25% off your first month of personalized care/of vitamins go to www.TakeCareOf.com and use the promo code SOMETHING Ancestry DNA. For 20% off your Ancestry DNA Kit go to www.ancestry.com/somethingGlip. Get a free Glip account at www.glip.com/somethingMadison Reed. For 10% off plus free shipping on your first order go to www.Madison-Reed.com/something

Even the best drivers get in serious accidents – usually because of bad drivers. So we start this episode with a look at why good drivers get into accidents and how to steer clear of them http://www.smartmotorist.com/traffic-and-safety-guideline/how-good-drivers-get-killed.htmlA lot of us don’t’ sleep very well. Often the problem is so chronic that we convince ourselves that it is normal but it is not according to Dr. Barry Krakow. Dr. Krakow is a board certified internist and sleep disorders specialist and author of the book Sound Sleep Sound Mind: 7 Steps to Sleeping Through the Night (https://amzn.to/2RvmGbf). He joins me with effective strategies to improve your sleep. By the way his website is www.sleeptreatment.com Ever been in a situation where you really need to feel powerful and confident but were feeling exactly the opposite? Well, there is a very effective tactic that can really boost your power and confidence and it only takes a moment. http://www.businessinsider.com/a-simple-exercise-to-make-you-powerful-2015-10Just about everyone has felt a bit out of place at work or other professional setting. But maybe that’s a good thing. Jennifer Romolini felt like an outcast all her professional life yet managed to use that to her advantage and succeed anyway. In fact she took what she discovered along the way and put it in a book called Weird in a World That's Not (https://amzn.to/2NlWGvO). If you have ever felt like a nerd or that you didn’t belong in an organization, listen as Jennifer explains how to use your uniqueness to reach your goals. This Week's Sponsorscare/of. For 25% off your first month of personalized care/of vitamins go to www.TakeCareOf.com and use the promo code SOMETHING Ancestry DNA. For 20% off your Ancestry DNA Kit go to www.ancestry.com/somethingGlip. Get a free Glip account at www.glip.com/somethingMadison Reed. For 10% off plus free shipping on your first order go to www.Madison-Reed.com/something

Behold the woozy face emoji: https://twitter.com/jeremyburge/status/1047186613028225024 Anyway, we're getting some new emoji in iOS 12.1: https://www.macrumors.com/2018/10/02/ios-12-1-new-emoji-characters-coming/ Dan's photo with his iPhone XS: https://www.instagram.com/p/BoXMRxrlMcY/?taken-by=dmoren Remember Microsoft HoloLens? https://en.wikipedia.org/wiki/Microsoft_HoloLens Microsoft did announce some stuff, even if we weren't excited about their event: https://www.theverge.com/2018/10/2/17929822/microsoft-surface-event-2018-highlights-news-recap-surface-laptop-pro Our thanks to Glip (http://glip.com/rebound) team messaging and collaboration in one digital workspace. Glip's all-in-one task management is a fast and effective to get everyone on the same page. Sign up for a free Glip account by going to glip.com/rebound (http://glip.com/rebound).

You probably just assume food grown organically is healthier – and maybe it is. But you also probably think that organic food tastes better. You may not think you think that – but you do. We start this episode with an explanation as to why. http://www.dailymail.co.uk/health/article-2302835/Organic-food-labels-trick-thinking-food-healthier-tastier.htmlConspiracy theories abound! I’m sure you’ve heard that some people believe the U.S. government was behind the 9/11 attacks or the Holocaust never happened or that the mafia really killed President Kennedy – or was it Castro? Where do these theories come from? Why do people believe them? And how do you have a conversation with someone if you think what they believe is crazy? Mick West, author of the book, Escaping the Rabbit Hole: How to Debunk Conspiracy Theories using Facts, Logic, and Respect (https://amzn.to/2R1HyXI) has researched conspiracy theories and the people who believe them and he has some great insight and advice for the next time you find yourself talking to someone who believes the world is really flat!Over half the population has foot problems that hamper their daily lives. So I reveal some proven strategies to help alleviate and/or prevent those problems so your feet stay happy. http://www.nytimes.com/ref/health/healthguide/esn-footpain-ess.htmlEvery culture is governed by rules – whether it is a nation, an organization, group or a family. Some cultures have very tight and strict rules while others take a more laid back approach. But which is better? Do you humans excel under strict regulations or is loose and easy a better way? Well, it all depends, according to cultural psychologist Michele Gelfand author of the book, Rule Makers Rule Breakers : How Tight and Loose Cultures Wire Our World (https://amzn.to/2xRrRcE). She joins me to explain the fascinating reasons why different cultures adopt tight or loose controls and how those rules impact the lives of people they affect.This Week's SponsorsRobinhood. To open your free account and get your FREE stock like Apple, Ford, or Sprint to help build your portfolio! Sign up at something.robinhood.comAncestry. To get 20% off your Ancestry DNA Kit go to www.ancestry.com/somethingGlip. To open your free, full-featured GLIP account go to www.glip.com/something

You tip the waiter at the end of a meal for a job well done. But when it comes to tipping the maid and other people at a hotel, it is actually better to tip them at the beginning of your stay so you get better service in the days to come. That’s just one of the very savvy travel tips with which we begin this episode of the podcast. http://www.mensjournal.com/expert-advice/travel-mistakes-to-avoid-20131217/packing-for-the-long-haulDo we really have free will? Does the placebo effect actually work? Have aliens tried to contact us? These are some of the fascinating mysteries that still baffle scientists. Science writer Michael Brooks, author of the book 13 Things That Don't Make Sense: The Most Baffling Scientific Mysteries of Our Time (https://amzn.to/2NvuAmO) joins me to explore some of these mysteries and explains what we do know and what we don’t know about them. Chewing gum may not be proper etiquette in many social situations but chewing gum does have some real benefits – particularly when you are stressed out. I’ll explain why have some gum in your pocket is almost always a good idea. https://greatist.com/happiness/does-chewing-gum-reduce-anxiety2018 marks the 60th anniversary of NASA. And while space launches aren’t quite the big deal they once were, NASA is still doing a lot of impressive work. John Logsdon has been keeping his eye on NASA for a long time. John is the founder of the Space Policy Institute at George Washington University, former member of the NASA Advisory Council and he served on the Columbia Space Shuttle Accident Investigation Board in 2003. He is the editor of a new book that just came out celebrating 60 years of NASA called The Penguin Book of Outer Space Exploration (https://amzn.to/2DoYWmm) and joins me to discuss some really interesting stories about the US space program you probably never knew.This Week's SponsorsRobinhood. To open your free account and get your FREE stock like Apple, Ford, or Sprint to help build your portfolio! Sign up at something.robinhood.comAncestry. To get 20% off your Ancestry DNA Kit go to www.ancestry.com/somethingGlip. To open your free, full-featured GLIP account go to www.glip.com/something

Do you feel like you could be doing more... but there’s just not enough time?   Whenever we feel like we’re running into a ceiling of achievement, when we feel like we just can’t quite do anymore, we’re just missing a person. As Gary Keller says, “No one succeeds alone.”   That’s why we’re sharing this conversation with Brindley Tucker, a KW MAPS Coach and the founder of Your Realty Leverage. But today’s episode isn’t about succeeding in real estate – it’s about being the type of person who can recruit and retain amazing talent, in whatever you do, so that you can break through whatever ceiling of achievement you perceive to be in your life.   And if you didn’t hear Brindley’s first episode, Ep 78 - How Mindset, Purpose, and Relationships Can Change Your Life in 5 Years or Less, we highly recommend listening to it as well. Her journey is truly incredible.     In this episode, you will learn... [4:45] How you overcome the limiting belief that you’re not ready to bring on another person [17:00] What 3 things you should be looking for in an administrative support partner [21:00] How to live your ONE Thing when you are working in an administrative or support role [28:20] How you can empower your support staff to live their ONE thing [45:35] The importance of having a 411 with your people every week   The ONE Thing to Implement From This Episode: The best business owners we’ve interacted with all have the habit of constantly looking for and forming relationships with new talent – and once they’re in a relationship, it’s truly a partnership.   The ONE Thing is the language of respecting each others’ priorities. And if no one succeeds alone, then we must succeed together.   One of the biggest obstacles is your environment – so who are the five people in your environment who most need to understand this collaborative language? We suggest you share the podcast with them today. It just may make your culture that much more productive.   Links & Tools From This Episode Learn more at yourrealtyleverage.com Connect with Bindley on LinkedIn Listen to Ep 78 - How Mindset, Purpose, and Relationships Can Change Your Life in 5 Years or Less | Brindley Tucker Listen to The Habit that Cost $100MM to Learn and Why It Was Worth It: Part 1 | Part 2 Read Rocket Fuel: The One Essential Combination That Will Get You More of What You Want from Your Business by Gino Wickman and Mark C. Winters   AWESOME FREE RESOURCES FOR YOU! Head over to the1thing.com/event to sign up for The ONE Thing Couples Goal Setting Retreat (Nov. 17-18, 2018 in Austin, TX) Get more support & accountability: Join the Living Your ONE Thing Community The Kick Ass Guide To Accountability Form your first power habit with your 66 Day Challenge Calendar Check out our awesome blog!   --   Are you hiring?   Gary Keller once said, “If you want to live an extraordinary life, it requires that you master something – and it only has to be ONE thing.” Geoff chose to master recruiting great people, so we know that finding the right people can be a huge challenge. That’s why we’re excited to introduce you to ZipRecruiter, a platform that finds the right job candidates for you. In fact, 80% of employers who post a job get a qualified candidate in just one day. And ZipRecruiter is inviting listeners of The ONE Thing to try for FREE – all you have to do is go to ziprecruiter.com/produktive.  --   Does your work environment support your goals? Is your team working as quickly as they could be? Unlock your team’s potential with one unified online workspace to chat, track tasks, manage a team calendar, share and make notes on files, host video meetings, and screenshare - all inside one integrated platform. 64% of Glip users reported delivering projects faster than before. 88% of Glip users say they’re more informed about their organization’s projects. Time is money. Isn’t it time you invested yours wisely? Sign your team up for free to at glip.com/productive. The ONE Thing is produced by Podcast Masters

People who travel a lot have to come up with their own travel hacks and secrets in order to stay sane! Several of the people who work for CNN and travel as part of their job, put together a bunch of really great tips and tricks they have learned from years and years of traveling – often by learning things the hard way. We begin this episode by sharing these great travel secrets so you can put them to use on your next trip. http://www.egyptindependent.com//news/20-biggest-travel-mistakesCan you learn to be lucky? The idea sounds weird – right? Because luck is just a matter of random chance. Or is it? Karla Starr, author of the book, Can You Learn to Be Lucky? https://amzn.to/2Q8Eb0j as looked at the science of luck (yes there is such a thing) and joins me to explain why some people just seem to be extremely lucky and what you can do to improve your luck. Could it be true that overweight people live longer? Since like forever, we’ve all been told that being thin is what helps you live longer. But there does seem to be a loophole in the theory. While it’s not a reason to let yourself go and gain a lot of weight, having a few extra pounds can be beneficial and I will explain why. http://healthland.time.com/2013/01/02/being-overweight-is-linked-to-lower-risk-of-mortality/You make a lot of important - even life-altering - decisions in your life. But I bet you were never taught HOW to make a decision. Well, it turns out how you make those important decisions really matters. And there is a way to improve your chances of making the right decision if you have a better understanding of the decision making process. Steven Johnson, author of the book Farsighted: How We Make the Decisions That Matter the Most https://amzn.to/2NlgWl9 explains how you can make the RIGHT decision.This Week's SponsorsGlip. Get a free Glip account at www.glip.com/somethingcare/of Vitamins. For 25% off your first month of personalized care/of vitamins go to www.TakeCareOf.com and use the promo code SOMETHING Hoka One One. Get free expedited shipping on your first pair of shoes by going to www.hokaoneone.com/SYSK and use the promo code SYSKHotel Tonight. Download the app Hotel Tonight to your phone and get $25 off your first eligible booking.Realtor.com. Start your next home search at www.Realtor.com

Whenever you get a new credit card in the mail, you are encouraged to sign the back of it. In fact many say, “Not valid until signed.” But should you sign the back of your credit cards? For security reasons, maybe not. But there is something you might want to write in that little box instead. We start the episode by discussing that. http://www.straightdope.com/columns/read/1444/should-you-sign-the-back-of-your-credit-cardsSupposedly the average American home has about $2600 worth of stuff collecting dust that could be turned into cash on eBay or a garage sale. But how do you know what stuff? Brian Kathenes is a managing partner at National Appraisal Consultants in New York and author of the book, Betcha Didn’t Know That! https://amzn.to/2NzLb4G. Brian joins me to offer some advice on what to look for in your attic or your parents’ attic that could be worth a lot of money – as well as things that aren’t worth wasting time on. So what’s the difference between green tea and plain old black tea? Green tea has certainly gotten a lot of great publicity for all its health benefits but could regular tea be just as good for you? You just might be surprised to hear this. http://www.webmd.com/food-recipes/antioxidants-in-green-and-black-teaHow do you get ahead in your career? If you care, you have probably already checked out various experts who talk about the importance of networking, a good resume and a firm handshake. But there are some lesser known strategies that are equally – if not more – powerful. Employment expert Vicky Oliver author of the book, 301 Smart Answers to Tough Interview Questions https://amzn.to/2Pv8Bsv joins me to offer some lesser known but powerful suggestions to move up the career ladder.This Week's SponsorsGlip. Get a free Glip account at www.glip.com/somethingcare/of Vitamins. For 25% off your first month of personalized care/of vitamins go to www.TakeCareOf.com and use the promo code SOMETHING Hoka One One. Get free expedited shipping on your first pair of shoes by going to www.hokaoneone.com/SYSK and use the promo code SYSKHotel Tonight. Download the app Hotel Tonight to your phone and get $25 off your first eligible booking.Realtor.com. Start your next home search at www.Realtor.com

Dit was ‘n naweek propvol sport en daarom gesels ons hierdie week oor tennis, sokker, rugby en krieket. Kevin Anderson maak Suid-Afrika trots deur al die pad tot die eindstryd van Wimbledon te vorder. Frankryk en Kroasië plaas die kersie op ‘n opwindende Wêreldbeker-sokkertoernooi koek en nou is alles verby. Die Sharks glip in by die Superrugby uitspeelrondtes se agterdeur en die Proteas is nou nog duiselig na Sri Lanka se draaiboul-aanslag.  Dit alles in hierdie week se Sportmal Podcast met my Kobus Pretorius. Deel 1: Wimbledon eindstryd (0m 38s) Deel 2: Sokker eindstryd (12m 56s) Deel 3: Superrugby (23m 17s) Deel 4: Proteas in Sri Lanka (39m 22s) Beskikbaar op iTunes, Apple Podcasts, Android, Spotify en SoundCloud.

Er Svend Brinkmann socialist i populærpsykologisk forklædning? I Eksilårene gennemgår Anne og Simon Svend Brinkmanns nyeste bog Gå Glip. Vi giver en gennemgang af indholdet og dykker særligt ned i bogens forståelse af kapitalismen og forbrugersamfundet. Vi tager en diskussion af, hvordan vores begær bliver rettet af samfundet, uden vi som sådan har synderlig kontrol over det. Herunder kommer vi i det sidste segment ind på en snak om hvilke elementer et psykisk sundt socialistisk samfund må have.

RingCentral have commissioned some research in their Zen Survey examining collaboration, where they try to establish the most efficient ways of working. The huge amount of communication and collaboration platforms available has increased the complexities for organisations when trying to optimise their workflows. Communication and collaboration methods vary according to various factors, including industry verticals but also within the different generations of an organisation's workforce. We take a look at the best ways to avoid disruption and ensure productivity.

The Pit Stop is a weekly mini-episode from In The Past Lane, the podcast about history and why it matters. Every Monday The Pit Stop tells you what happened in American history this week - in under 5 minutes! We drop these minis in between our full-length episodes that feature interviews with historians about their latest books, feature pieces, and more.  Here’s what happened in American history the week of June 4, 2018.  BIRTHDAYS June 5 1919 - Richard Scarry born in Boston, MA Children’s book author who brought us characters like Glip and Glop, Pip Pip, and of course Lowly Worm. June 6 1755 - Nathan Hale born Coventry, CT Hale was an important spy in the early months of the Rev War. But he was captured by the British and hanged in Manhattan in Sept 1776. But not before he allegedly said, “I only regret that I have but one life to lose for my country.”   June 9 1768 - Samuel Slater born in Belper, England Slater is considered the “father of the industrial revolution” in America.  As a youth, he worked in a textile factory. In 1789, armed with this knowledge, he immigrated to the United States. Four years later in 1893 in Pawtucket, RI he established the first successful textile mill in the US, a feat that essentially launched the industrial revolution in America. June 9 1916 - Robert McNamara born San Francisco, CA McNamara was a very successful business executive with the Ford Motor Company. But he’s mainly remembered for his service as the Secretary of Defense, from 1961 to 1968, during which time he presided over the controversial and ultimately disastrous Vietnam War. June 10 1895 - Hattie McDaniel born Wichita, KS McDaniel was the first African American to win an Academy Award. She earned the honor for her role as Mammy in the 1939 blockbuster film, Gone With The Wind. June 10 1915 - Saul Bellow born in Canada Bellow was a prolific and highly decorated novelist. He won all the major honors, including the Pulitzer Prize, Nobel Prize, and National Book Award, for novels such as Humboldt's Gift and The Adventures of Augie March. Saul Bellow once said, “You never have to change anything you got up in the middle of the night to write.” EVENTS/ ANNIVERSARIES June 4 1942: The Battle of Midway (June 4-7) begins. This was a major US victory just 6 months after Pearl Harbor. Led by Admiral Chester Nimitz the US Navy inflicted devastating losses on Imperial Japan’s Navy, losses it never recovered from. US forces sank 4 carriers and 1 heavy cruiser, while also destroying 248 aircraft. June 6 1968 Sen Robert F. Kennedy dies from a gunshot wound sustained just minutes after he was declared the winner in the California primary in the race for President. “There are people in every time and every land who want to stop history in its tracks. They fear the future, mistrust the present, and invoke the security of a comfortable past which, in fact, never existed.” If you want to learn more about RFK, check out Episode 006 of In The Past Lane where I speak with Larry Tye, author of Bobby Kennedy: The Making of a Liberal Icon. June 6 is also the anniversary of D-Day, which began June 6, 1944. On that day, Allied forces launched a massive amphibious invasion of Nazi-occupied France. It was the beginning of a long and bloody, but ultimately successful effort to defeat Nazi Germany. Anyone who’s seen the movie “Saving Private Ryan” has a sense of the human cost of this epic battle. June 6 1933: the first drive-in movie theater in the US opens in Camden, New Jersey. June 10, 1935: Dr. Robert Smith and his friend William G. Wilson founded Alcoholics Anonymous. June 10, 1752: Benjamin Franklin conducted his famous experiment that demonstrated the electrical nature of lightning. Franklin flew a kite during a thunderstorm and collected an electrical charge in what was called a Leyden jar. He published the results and soon became an international celebrity. LAST WORD Let’s give it to Dwight D. Eisenhower. On June 6, 1944, D-Day, he issued the following Order of the Day: Soldiers, Sailors, and Airmen of the Allied Expeditionary Force: You are about to embark upon the Great Crusade, toward which we have striven these many months. The eyes of the world are upon you. The hopes and prayers of liberty-loving people everywhere march with you. In company with our brave Allies and brothers-in-arms on other Fronts you will bring about the destruction of the German war machine, the elimination of Nazi tyranny over oppressed peoples of Europe, and security for ourselves in a free world. Your task will not be an easy one. Your enemy is well trained, well equipped, and battle-hardened. He will fight savagely. But ... The tide has turned. The free men of the world are marching together to victory. I have full confidence in your courage, devotion to duty, and skill in battle. We will accept nothing less than full victory. Good Luck! And let us all beseech the blessing of Almighty God upon this great and noble undertaking. OK, people. That’s your history fix for the week. Now put it in drive and go make your own history. For more information about the In The Past Lane podcast, head to our website, www.InThePastLane.com  Production Credits for The Pit Stop Original music and Voice Over by Devyn McHugh  Additional music by Blue Dot Sessions, "Pat Dog" via the Free Music Archive  Executive Producer: Lulu Spencer Associate Producer: Tyler Ferolito Technical Advisors: Holly Hunt and Jesse Anderson Photographer: John Buckingham Graphic Designer: Maggie Cellucci Website by: ERI Design Legal services: Tippecanoe and Tyler Too Social Media management: The Pony Express Risk Assessment: Little Big Horn Associates Growth strategies: 54 40 or Fight © In The Past Lane, 2018

I denne uges podcast taler Jes Stein Pedersen med nejhatten Svend Brinkmann. Den populære forfatter og professor har nu udgivet sin tredje bog, ’Gå glip’, som han bliver interviewet om foran et veloplagt publikum i Politikens Hus. Her fortæller han om mådehold, sociale medier og selvdannelse. Vært: Jes Stein PedersenRedaktion: Sille Westphal, Kathrine Wadsholt og Hanne Budtz-JørgensenJingle: Peter Kristian Sejersbøl

Download episoden Googles Keyword Planner er stadig grundpille i enhver søgeordsanalyse. Men der findes også andre værktøjer og teknikker, du kan bruge til at finde nye søgeord til dit SEO- og AdWords-arbejde. I episode #26 af Marketing Brief taler Halfdan og Emil om deres yndlingsværktøjer til søgeordsanalyser. Hør den på 10 minutter før din nærmeste konkurrent.

It's Part 2 of our conversation with Mike Gatti of MASSolutions. In this episode we talk about MASSolutions' No BS Process of market intel, the marketing roadmap and and cohesive messaging all targeted at ROI. One of Mike's favorite tools to share with the audience is Glip, an online project management system MASSolutions uses to keep communication flowing on project for efficiency and timliness. He's also a big fan of Overcast for podcast listening.Want to learn more about Mike Gatti? Contact him at gatti@massolutions.com

Yantasy doesn't think enough strong women have featured on Outside The Underappreciateds Studio. Tori Crisp - Anastasia Glip Timothy Fishlock - Qwentin Alice Fitzgerald - Chloe Thomas Midena - Yantasy High

Mads Brynnum er på besøg. Han har vundet DM i Stand-up engang, lavet en masse siden, og har købekage med! Morten har været vært på huset, og Mikkel skal til Distortion. Mads Brynnum