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Auckland's Karangahape Road restaurants say road works, no parking and anti-social behaviour are putting customers off. Several hospitality businesses along the colourful strip have been forced to shut their doors or move as tough economic times bite, including some veteran restaurants, Fabio Bernardini, the owner and chef of Latin eatery Tempero speaks to Lisa Owen.
No Alvorada Gourmet de hoje, Flavio Trombino começa uma série de receitas de uma panela só. Para abrir os trabalhos, nosso chef te ensina a preparar galinhada. Confira! Ingredientes: 1 frango cortado nas juntas 2 xícaras de chá de arroz 1 cebola 2 dentes de alho 200 G de bacon 1 colher de sopa de coloral 1 colher de chá de cúrcuma Meio KG de tomates Tempero caseiro See omnystudio.com/listener for privacy information.
"Alguns trabalhos criativos vão desaparecer... mas talvez eles não devessem nem existir." Essa fala é de Mira Murati, chefe de tecnologia da OpenAI. Num contexto em que ferramentas de IA generativa avançam sobre todos os domínios da criatividade humana — design, escrita, música, audiovisual —, é inevitável que profissionais desses campos fiquem preocupados com o futuro.No episódio de hoje, exploramos a relação entre trabalho criativo, a facilitação trazida pelas ferramentas de IA e o diferencial que a experiência humana pode oferecer. O que é criatividade, para começo de conversa? E será que haverá estímulo para o aperfeiçoamento técnico num mundo em que a IA diminui tanto a barreira de entrada para profissionais criativos? Dá o play e vem com a gente! ParticipantesThiago MobilonJosué de OliveiraAna MarquesIsabela GiantomasoVitor PáduaCitado no episódioYouTube quer acordo com gravadoras para usar músicas em treinamento de IAMande seu recadoGrupos da Caixa Postal do Tecnocast: Telegram: t.me/caixapostaltecnocast WhatsApp: tbnet.me/caixapostaltecnocast Você pode mandar comentários (inclusive em áudio, vai que você aparece no Tecnocast?), dúvidas, críticas e sugestões. Participe!Se preferir, você pode se comunicar conosco pela Comunidade e através do e-mail tecnocast@tecnoblog.net.Entre também nos Canais do TB no WhatsApp Canal do Tecnoblog Canal do Achados do TB CréditosProdução: Josué de OliveiraEdição e sonorização: Ariel LiborioArte da capa: Vitor Pádua
A l'occasion du Refugee Food Festival (4 au 24 juin 2024), je suis allé à la rencontre de deux cheffes réunies pour l'occasion : la première vous la connaissez si vous avez écouté son histoire sur ce podcast et si ce n'est pas le cas, je vous invite à vous faire une session de rattrapage, je retrouve aujourd'hui ma chère Alessandra Montagne, aujourd'hui à la tête des cuisines de Tempero et Nosso. Deuxième cheffe à ce micro pour ce talk, une cheffe indépendante, Lulua Elsarraj. Ces deux-là ont un point commun : elles font partie de l'association Refugee Food. Tous les ans, l'association organise le Refugee Food Festival, dont Alessandra est la marraine pour cette édition 2024. Le festival s'est déroulé en ce mois de juin dans 12 villes de France autour d'une idée simple : “créer des collaborations entre des cuisiniers et cuisinières réfugié.e.s et des restaurants locaux ou des artisans et artisanes de métiers de bouche”. Alessandra et Lulua ont donc créé un binôme pour réaliser un dîner à quatre mains, c'était le 12 juin dernier et j'ai pu les croiser quelques heures avant ce grand rendez vous… J'ai voulu profiter de l'occasion pour parler de cette association qui œuvre pour l'intégration par la cuisine, et j'ai voulu qu'on revienne avant toute chose sur les parcours de ces deux cheffes, sur leurs origines pour voir comment finalement, le mariage des influences se traduit en cuisine : Alessandra est brésilienne, Lulua est palestinienne. Alors vous allez voir ça donne une partition voyageuse, gourmande, souriante et forcément solidaire!
Comida indiana em Pinheiros. Comida simples, vibrante, perfumada e cheia de sabor no restaurante Tempero IndianoSee omnystudio.com/listener for privacy information.
À Rádio Observador Manuel Monteiro considera que o CDS tem de começar a definir que políticas quer promover e assume que o "não é não" ao Chega é mau para os objetivos da AD.See omnystudio.com/listener for privacy information.
#899 Copo Stanley, asteróides do Armagedom e um tempero para longevidade
Antes de se tornar proprietária de dois restaurantes em Paris e ser convidada para comandar um dos restaurantes do Museu do Louvre, a chef brasileira teve enfrentou diversos obstáculos. Aos 22 anos, foi para Paris e deixoupra trás um passado de muita pobreza, um relacionamento abusivo e um filho de 3 ano. Muito jovem, conseguiu se manter fortalecida por um objetivo: construir um novo futuro pra ela e para os seus. Hoje, aos 46, ela segue vivendo na capital francesa, agora na companhia dos dois filhos. É apadrinhada pelo grande chef francês Alain Ducasse, que foi justamente quem a convidou para esse projeto do Museu Louvre. A trajetória gastronômica de Alessandra começa na pequena cidade de Poté, em Minas Gerais, em que ela vivia com os avós e onde aprendeu a cozinhar. Apesar de ter nascido na comunidade carioca do Vidigal, foi em Minas que ela cresceu. Na França, Alessandra começa a cozinhar para os amigos o que aprendeu na roça. Se matricula em uma escola de gastronomia francesa, a Médéric (Mêdêrríc), e tenta voar solo. Abre um pequeno restaurante, o Tempero, que logo no primeiro dia rendeu filas na porta e seguiu cheio. Seu segundo restaurante, Nosso, traz em suas receitas o que oferecem os produtores mais próximos, com ingredientes sazonais. Ela se interessa também por plantas e ervas medicinais,que fazem parte de sua memória de infância, e soma a isso novas combinações. Escuta esse nosso papo em que ela compartilha sua trajetória e ensinamentos.
Je suis Jessica Troisfontaine et vous écoutez le podcast Ressentir. Aujourd'hui, j'ai le plaisir de recevoir Alessandra Montagne. Alessandra est la cheffe et propriétaire du restaurant Nosso, situé dans le 13ème arrondissement de Paris. Dans cet épisode, elle raconte son enfance vécue dans la plus grande simplicité au Brésil et l'incidence qu'a eu sur sa personnalité le fait de se voir confier à sa grand-mère alors qu'elle n'avait que quelques jours et de devenir ainsi la petite 10ème d'une fratrie. Elle détaille son arrivée à Paris à 22 ans, les petits boulots qu'elle a enchainés et la manière dont la nourriture a pris de plus en plus de place dans sa vie, jusqu'à devenir son métier. Elle explique à quel point la cuisine l'a sauvée mais aussi la difficulté à accepter de se faire appeler cheffe et le syndrome de l'imposteur dont elle peine à se défaire. Mais avec Alessandra, nous avons aussi discuté de la façon dont elle s'y est prise pour évoluer vers la gastronomie, de la réalité économique du secteur, de lutte contre le gaspillage alimentaire, de son amour pour la France et de sa réconciliation avec le Brésil. Je vous propose à présent de ressentir avec la sensibilité d'Alessandra. Cet épisode est soutenu par Absolution, qui a entrepris une démarche sincère, exigeante et pionnière il y a 15 ans en proposant des soins cosmétiques certifiés bio, mêlant actifs botaniques et minéraux, adaptables à toutes les humeurs de peau. Leur démarche m'évoque la cuisine que je préfère : celle qui ne fait que sublimer la nature, puisqu'elle contient tout ce qu'il nous faut, mais en ne sacrifiant rien à l'esthétique, puisque le beau nous fait autant de bien que le bon et le bio. Grâce au code « Ressentir », pour toute commande passée chez Absolution, vous recevrez mon produit coup de cœur - le masque velours repulpant - en format découverte dès 50 € d'achat. La musique et l'illustration sonore sont de Pandore. Le montage a été réalisé par Touch Prod. Et si vous vous posez d'autres questions ou si vous avez des suggestions, n'hésitez pas à m'écrire un message via mon compte Instagram @jessica_troisfontaine.
Join Shane Gibson as he chats with Blair Tempero on that last five years since they started the AgileData Podcast together. You can get in touch with Blair via LinkedIn If you want to read the transcript for the podcast head over to: Listen to more podcasts on applying AgileData patterns over at https://agiledata.io/podcasts/ Read more on the AgileData Way of Working over at https://wow.agiledata.io/way-of-working/ If you want to join us on the next podcast, get in touch over at https://agiledata.io/podcasts/#contact Or if you just want to talk about making magic happen with agile and data you can connect with Shane @shagility or Nigel @nigelvining on LinkedIn. Subscribe: Apple Podcast | Spotify | Google Podcast | Amazon Audible | TuneIn | iHeartRadio | PlayerFM | Listen Notes | Podchaser | Deezer | Podcast Addict | Simply Magical Data
O INCRÍVEL TEMPERO QUE COMBATE REFLUXO E GASES (alecrim) - Dr Alain Dutra - #saude #shorts Assista ao vídeo completo: 7 TEMPEROS E ERVAS que se usados TODOS OS DIAS podem PREVENIR DIVERSAS DOENÇAS - Dr Alain Dutra https://youtu.be/-zbsXmJUyDg Descubra 7 temperos e especiarias que melhoram sua saúde: manjericão, folha de louro, coentro, cominho preto, orégano, alecrim e anis estrelado. ⚠️AVISO LEGAL⚠️ A informação médica contida nesse vídeo é somente para fins de informação geral e não deve ser usada para qualquer finalidade de diagnóstico ou tratamento. Esta informação NÃO cria nenhuma relação médico-paciente e não deve ser usado como substituto de diagnóstico ou tratamento profissional. Por favor, consulte seu médico antes de tomar qualquer decisão sobre cuidados de saúde e NÃO pare nenhuma medicação sem o consentimento do seu médico. A Medicina é uma ciência em constante mudança, os vídeos são produzidos baseados nos Artigos Científicos mais recente até a data. De acordo com Art. 8º da Resolução CFM 1974/11 de Publicidade do Código de Ética Médica, os vídeos têm somente caráter de prestar informações de fins estritamente educativos. Dr. Alain Dutra -
O ÚNICO TEMPERO CAPAZ DE PREVENIR O DIABETES - Dr Alain Dutra - #saude #shorts Assista ao vídeo completo: 7 TEMPEROS E ERVAS que se usados TODOS OS DIAS podem PREVENIR DIVERSAS DOENÇAS - Dr Alain Dutra https://youtu.be/-zbsXmJUyDg Descubra 7 temperos e especiarias que melhoram sua saúde: manjericão, folha de louro, coentro, cominho preto, orégano, alecrim e anis estrelado. ⚠️AVISO LEGAL⚠️ A informação médica contida nesse vídeo é somente para fins de informação geral e não deve ser usada para qualquer finalidade de diagnóstico ou tratamento. Esta informação NÃO cria nenhuma relação médico-paciente e não deve ser usado como substituto de diagnóstico ou tratamento profissional. Por favor, consulte seu médico antes de tomar qualquer decisão sobre cuidados de saúde e NÃO pare nenhuma medicação sem o consentimento do seu médico. A Medicina é uma ciência em constante mudança, os vídeos são produzidos baseados nos Artigos Científicos mais recente até a data. De acordo com Art. 8º da Resolução CFM 1974/11 de Publicidade do Código de Ética Médica, os vídeos têm somente caráter de prestar informações de fins estritamente educativos. Dr. Alain Dutra -
O TEMPERO QUE PROTEGE SEU CORAÇÃO - Dr Alain Dutra - #saude #shorts Assista ao vídeo completo: 7 TEMPEROS E ERVAS que se usados TODOS OS DIAS podem PREVENIR DIVERSAS DOENÇAS - Dr Alain Dutra https://youtu.be/-zbsXmJUyDg Descubra 7 temperos e especiarias que melhoram sua saúde: manjericão, folha de louro, coentro, cominho preto, orégano, alecrim e anis estrelado. ⚠️AVISO LEGAL⚠️ A informação médica contida nesse vídeo é somente para fins de informação geral e não deve ser usada para qualquer finalidade de diagnóstico ou tratamento. Esta informação NÃO cria nenhuma relação médico-paciente e não deve ser usado como substituto de diagnóstico ou tratamento profissional. Por favor, consulte seu médico antes de tomar qualquer decisão sobre cuidados de saúde e NÃO pare nenhuma medicação sem o consentimento do seu médico. A Medicina é uma ciência em constante mudança, os vídeos são produzidos baseados nos Artigos Científicos mais recente até a data. De acordo com Art. 8º da Resolução CFM 1974/11 de Publicidade do Código de Ética Médica, os vídeos têm somente caráter de prestar informações de fins estritamente educativos. Dr. Alain Dutra -
Margaret Tempero, MD, is an internationally renowned expert in pancreatic cancer, a Professor of Medicine and Director of the Pancreas Center at the UCSF Comprehensive Cancer Center. She organized the first Pancreas Cancer Think Tank in 1999 and chairs The Pancreatic Cancer Action Network's (PanCAN) Scientific and Medical Advisory Board. She was recently inducted into the prestigious Giants of Cancer Care. A thought leader in cancer, she is a former president of the American Society of Clinical Oncology and American Pancreatic Association and currently serves on the ASCO Conquer Cancer Foundation Board. She also serves as the Editor of Chief of Journal of National Comprehensive Cancer Network. “I remember asking a mentor of mine, ‘What does success mean?'” In her mind, Dr. Margaret Tempero expected an obvious answer: Some prestigious designation, a decorated award, maybe some groundbreaking research to her name; but when Dr. Ann Kessinger responded with the most fundamental truth of medicine, it revolutionized her medical philosophy to its core: “You're successful when you're improving the lives of your patients, plain and simple.” Join us for another episode of The Medicine Mentors as Dr. Margaret Tempero shares the true definition of success in medicine, teaches us how to improve the lives of our patients, and emphasizes getting to know the patient as a person before we know them by their disease. Pearls of Wisdom: 1. Success in medicine is found when you're improving the lives of your patients. Regardless of how you do it, the patient must be the first and center focus. 2. Get to know your patient as a person before you know them as a disease. It's as simple as asking them to tell you about themselves. Know the patient so you can help cater your discussion to a field that they understand. 3. Mentorship can be thought of like tennis; a bidirectional process where if your opponent is better, you do better. Mentees have to bring the full initiative to the mentor so they can play back.
As escolhas das carnes para as ceias de Natal e ano novo geralmente são opções mais gordurosas. No episódio de hoje, confira algumas dicas de carnes mais saudáveis e formas de temperar os pratos da melhor forma possível. Confira!See omnystudio.com/listener for privacy information.
Caio Soter traz uma ótima dica de tempero para assar um porco no natal.
durée : 00:04:57 - La chronique de Zazie Tavitian - par : Zazie Tavitian - Alessandra Montagne, cheffe des restaurants Nosso et Tempero, raconte l'histoire de la feijoada, ce plat brésilien à base d'haricots noirs mijotés et de porc. Ce plat national, cuisiné par les esclaves à qui les maîtres blancs ne laissaient que les bas morceaux, raconte l'histoire du Brésil.
Da tela da televisão diretamente para o Negócio em Dia, recebemos o cozinheiro, apresentador e empreendedor João Batista em um episódio especial em comemoração ao Dia do Empreendedor. Aperte o play e confira todo o carisma, bom humor e sabedoria do chef João Batista!
Matt sits down the a full St Thomas crew to talk about the growth of the program in the DI era, how the attacking units may adjust to multiple formations, new transfers/freshmen who could show in the rotation, and more!
A Dica da Tati é um quadro de alimentação saudável e um outro estilo de vida. Tati é espesclista e compartilha seus conhecimentos no programa Acredita em todos os domingos.
Proclamação do Evangelho de Jesus Cristo segundo Mateus 5,13-16 Naquele tempo, disse Jesus a seus discípulos: 13 "Vós sois o sal da terra. Ora, se o sal se tornar insosso, com que salgaremos? Ele não servirá para mais nada, senão para ser jogado fora e ser pisado pelos homens. 14 Vós sois a luz do mundo. Não pode ficar escondida uma cidade construída sobre um monte. 15 Ninguém acende uma lâmpada, e a coloca debaixo de uma vasilha, mas sim, num candeeiro, onde brilha para todos que estão na casa. 16 Assim também brilhe a vossa luz diante dos homens, para que vejam as vossas boas obras e louvem o vosso Pai que está nos céus".
Hoje em dia, os molhos de pimenta estão fazendo muito sucesso. Por isso, no Alvorada Gourmet de hoje, Flavio Trombino passa uma receita artesanal deste tempero. Confira! Ingredientes: 1 xícara de chá de vinagre 2 folhas de louro 2 cravos 2 colheres de sopa de açúcar demerara 1 colher de chá de sal 1 dente de alho Meia cebola 1 colher de azeite 200 G de pimenta dedo de moça See omnystudio.com/listener for privacy information.
Palavra compartilhada na reunião do dia 21 de maio de 2023.
In this JCO Article Insights episode, Emily Zabor interviews Dr. Gulam Manji from Columbia University Irving Medical Center. Dr. Manji provides insight into his editorial published in the April 10, 2023 JCO issue: "Adjuvant Gemcitabine and Nab-Paclitaxel Misses the Target in Pancreas Adenocarcinoma: Or Did an Effective Therapy Fall to the Definition of Recurrence?” (10.1200/JCO.23.00039). His editorial focuses on the JCO Original Report, “Adjuvant nab-Paclitaxel + Gemcitabine in Resected Pancreatic Ductal Adenocarcinoma: Results From a Randomized, Open-Label, Phase III Trial” by Tempero, et al on the APACT Trial. TRANSCRIPT The guest on this podcast episode has no disclosures to declare. Emily Zabor: Welcome to this JCO Article Insights episode for the April issue of JCO. This is Emily Zabor, one of JCO's editorial fellows. And today I am interviewing Dr. Manji from Columbia University on their editorial titled “Adjuvant Gemcitabine and Nab-Paclitaxel Misses the Target in Pancreas Adenocarcinoma: Or Did an Effective Therapy Fall to the Definition of Recurrence?” Dr. Manji, welcome to our podcast. You wrote this editorial to accompany the article, “Adjuvant Nab-Paclitaxel plus Gemcitabine in Resected Pancreatic Ductal Adenocarcinoma: Results from a Randomized Open-label Phase III Trial by Dr. Margaret Tempero and Colleagues.” That trial, called the APACT Trial, investigated the efficacy and safety of adjuvant nab-paclitaxel plus gemcitabine compared to gemcitabine alone in patients who had undergone resection for pancreatic ductal adenocarcinoma. So I wanted to ask if you could start by giving listeners a quick overview of the study design and the main findings from that trial. Dr. Gulam Manji: Yeah, sure, Emily. So, as you pointed out, it was a randomized phase III study in patients who had resected pancreatic carcinoma. The primary endpoint was independently assessed disease-free survival. Additional endpoints included investigator-assessed disease-free survival, overall survival, and safety. And we'll get back later on as far as the importance of investigator-assessed versus independently-assessed disease with survival because I think that that's the main point of discussion for today. The enrollment criteria were fairly stringent and included patients with macroscopic complete resection, ECOG performance status of either 0 or 1, and the peripheral tumor markers of CA 19-9 being less than 100. And patients were required to initiate adjuvant chemotherapy within 12 weeks. Patients received standard gemcitabine at 1000 milligrams per meter square, either with or without nab-paclitaxel of 125 milligrams per meter square once weekly for three weeks during every four-week cycle. Emily Zabor: Great. So I think that the main thing that we wanted to talk about today, and one of the main points you discuss in your editorial is the difference between the primary endpoint of independently assessed disease-free survival and the secondary endpoint of investigator-assessed disease-free survival. So can you describe the difference between those endpoints, how they were defined, and how they differed? Dr. Gulam Manji: Sure. So, independently-assessed DFS was determined by a radiologist who was blinded to treatment assignment, and new lesions followed RECIST 1.1 criteria. In contrast, the investigator-assessed recurrence was determined by the treating physicians using all available clinical information. So that could be abdominal pain, anorexia, probably elevation of peripheral tumor markers. And the other important aspect to the study is that the independent review was not performed in real-time to confirm investigator assessments. So patients who started subsequent therapy after recurrence by treating investigators were censured for the independently-assessed DFS analysis. So in this trial, 866 patients were randomized. And patients who are randomized to the experimental arm had a median independently assessed DFS of 19.4 months, while patients randomized to the control arm, which was gemcitabine alone, had a median DFS of 18.8 months. Now, when we compare that to the investigator-assessed DFS, the data looks quite different. Where the DFS was 16.6 months in the experimental arm compared to 13.7 months in the control arm. That is consistent with the five-year follow-up looking at the median overall survival, which was 41.8 months for the combination arm compared to 37.7 months for the gemcitabine alone arm. Emily Zabor: Okay, so there's some really interesting differences there. And I noticed that there were only 439 events according to the independently-assessed DFS versus 571 according to the investigator-assessed DFS. So that's a big difference in the number of events that I guess is coming from that additional censoring that was occurring due to the delay in the independently assessed endpoint. Is that right? Dr. Gulam Manji: Exactly. So you could envision a scenario where patients received chemotherapy and then on the investigator-assessed DFS, the investigators decided that the patient had recurred. However, that patient probably did not meet the RECIST or radiological criteria to determine that that patient had recurred. And hence, since it was not done in real-time, there was censoring that occurred for the independently-assessed DFS. So that's the reason why there was a difference in that number as you pointed out. The decision to use independent DFS, disease-free survival, really was to remove investigator-associated bias and increase rigor to the study, which is commendable. However, unfortunately, that's not how we normally treat patients with aggressive cancer who have undergone surgical reception. And knowing that imaging modality is limited in identifying those patients, particularly in those that have peritoneal disease, or even more importantly, the patients who have recurrence within the surgical bed, I think is the issue. Emily Zabor: Right. So the motivation behind selecting that endpoint was really good and well-motivated. Everybody wants to reduce bias and make sure we're taking out those kind of more subjective parts of identifying that. But it, unfortunately, missed some events as a result. Dr. Gulam Manji: Correct. I think that it delayed those events and that's what compromised the analysis because it was the limitations of the available modalities to determine when recurrence occurs. Emily Zabor: So how do these different definitions compare to other trials or previous trials? Dr. Gulam Manji: So previous trials that I'm aware of, it was the investigator-assessed DFS that had been used. And when you look at the data that was used in this trial, that concurs with what has historically been seen. And what I mean by that is that the original assumptions regarding DFS when this trial was being designed, used historical outcomes. Investigators see that DFS with adjuvant gemcitabine ranged anywhere from between 13.4 to 14.3 months. And the study had aimed to achieve a DFS improvement from 13.5 to 18.5 months. When you look at the investigator-assessed DFS, the ballpark of gemcitabine is very much in line with the previous historical data. So I think that the key discrepancy between the two DFS endpoints was likely a delay in accurately assessing disease recurrence when using the blinded radiological modality alone. And the second thing is, as you pointed out, a greater proportion of patients who were censored for independent assessments compared with those for investigator assessments was different. So that was between 40% versus 34%. So those two points, I think, were the key points that show the difference between independent versus investigator-assessed DFS and also that the independent-assessed DFS was not done in real-time. Emily Zabor: Yeah, that's really interesting and such a good point. And I think it really emphasizes how important it is to think carefully about these endpoint definitions in the design stage of these clinical trials and especially to think about when and why patients are getting censored and how that might impact the results. So how do these results of this trial then, given the negative result of the primary endpoint, but that positive result on the secondary investigator-assessed endpoint, how do these fit in with other trials? And what do you think that means for patient treatment recommendations? Dr. Gulam Manji: Excellent point. So just to be clear, the APACT study did fail to meet its primary endpoint and hence gemcitabine and nab-paclitaxel were not indicated for patients in the adjuvant setting. The current standard of care are either modified FOLFIRINOX or gemcitabine combination with capecitabine. And those two regimens really remain a standard of care for patients. So what I do is for fit patients, I prefer modified FOLFIRINOX. However, in patients who are not as fit, gemcitabine in combination with capecitabine is the alternative. Now, one could envision a scenario where gemcitabine and nab-paclitaxel may become relevant. It is, but only when I'm really pushed to do so, where I feel like there is no other regimen available optimally for a patient. And one could envision a scenario where you could have a patient who does not have the performance status to tolerate modified FOLFIRINOX and then you start that patient on gemcitabine in combination with capecitabine. However, I have experienced that that combination results in significant myelosuppression in patients in the United States. And then we have to do significant dose reductions or interruptions. Now, in that case, where I feel like I'm reducing the dose of capecitabine to a point where the patient may not be potentially benefiting from that regimen, it's impossible to determine what dose would be efficacious when you're doing those dose reductions. That is the only scenario where I may be able to be pushed to consider gemcitabine and nab-paclitaxel, but only after also discussing with the patient the results of the current data and there being limited efficacy. Emily Zabor: That makes sense. So the treatment you would select would really depend on some patient characteristics and then how they do on the different treatments. Dr. Gulam Manji: Correct. Emily Zabor: So what do you think are the next steps for research in this area and in this disease? Dr. Gulam Manji: I think that this clinical trial really demonstrated our inability to accurately pinpoint the time of disease recurrence using imaging modalities alone. And for patients who treat pancreas cancer, they would know that the recurrence patterns usually are either to the liver or to the peritoneum, or to the lung. However, in about 25% of the cases, the recurrence may be at the surgical site, and that's when things become tricky. After patients have undergone surgery, their scar tissue and the pancreas tumor is very dense, so it's difficult to determine that there's actually tumor growth. So that's where you really need help from other modalities. So should we get a PET scan? Is the patient symptomatic? Is a tumor marker going up in the absence of biliary obstruction? So all of those things need to be taken into account to truly pinpoint whether the patient has recurred or not. In peritoneal disease, you may need to ask the surgeons to help and have the patient undergo a laparoscopy to truly determine whether there is a peritoneal disease. And lastly, I think that incorporating ctDNA to better define whether there is a minimal residual disease will likely be a standard in the future. Emily Zabor: I see. Yeah, that makes sense. Incorporating some ctDNA biomarker information along with these really detailed clinical and possibly imaging assessments to determine recurrence seems like it would be really important in future trials to make sure you're capturing all of those recurrences accurately. Dr. Gulam Manji: Yeah, I think that that's critical before you can say that an adjuvant treatment is truly helping the patient. Emily Zabor: That's great. Well, I really learned a lot reading this article and speaking to you today. But before we end, is there anything else you'd like to share with our listeners? Dr. Gulam Manji: Yeah, so I think we know that for a majority of patients who undergo curative resection, unfortunately, the disease recurs. And I think that that implies that, really, pancreas cancer is a systemic disease at the time of diagnosis. And despite aggressive adjuvant therapy, the median DFS, OS, and five-year survival rate show that we are impacting only a subset of patients with six additional months of chemotherapy. So I think that identifying predictive markers of response to systemic therapy, better selection of patients for surgery, perhaps using total upfront neoadjuvant therapy, an institution of maintenance therapy, and patients who are at high risk for recurrence, perhaps using ctDNA as a marker to determine who those high-risk patients are, all leads to help better design and identify patients who should really be treated systemically and patients who should undergo surgery. And lastly, with some glimmers of success from personalized vaccines may be on the horizon. And I'm hoping in the near future to treat minimal residual disease so that we can get the best outcome with minimal toxicity for our patients. Emily Zabor: That's great. That sounds like an exciting development for a disease that seems really tricky. Dr. Gulam Manji: Agreed. Emily Zabor: Well, thank you so much. It has been a pleasure speaking with you, Dr. Manji, and thank you so much for joining me today on this episode of JCO Article Insights. This concludes the episode on the article “Adjuvant Gemcitabine and Nab-Paclitaxel Misses the Target in Pancreas Adenocarcinoma: Or Did an Effective Therapy Fall to the Definition of Recurrence?” Thank you for listening and please tune in for the next issue of JCO Article Insights. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity or therapy should not be construed as an ASCO endorsement. Show Notes: Like, share and subscribe so you never miss an episode and leave a rating or review. Guest Bio: Dr. Gulam Manji, MD, PhD is a medical oncologist at the Columbia University Irving Medical Center in New York. Articles: Editorial: Adjuvant Gemcitabine and Nab-Paclitaxel Misses the Target in Pancreas Adenocarcinoma: Or Did an Effective Therapy Fall to the Definition of Recurrence? Original Report: Adjuvant nab-Paclitaxel + Gemcitabine in Resected Pancreatic Ductal Adenocarcinoma: Results From a Randomized, Open-Label, Phase III Trial Find more articles from the April 10 issue.
L.H. Lourenço- A Magia do Tempero
Dès le lever du jour, dans les villages et les villes, au champ comme en cuisine, elles sont là à planter, à cueillir, à récolter, à vendre, à transformer, à conserver, à élever, à cuisiner : les femmes nourrissent le monde, mais le monde le sait-il ? Selon la FAO, 3% soit près de la moitié des femmes actives dans le monde travaillent dans l'agriculture, parfois jusqu'à 70/80% dans certains pays africains, 14% d'entre elles seulement sont détentrices de leur terre. Quels freins concrets, sociaux, limitent encore les femmes dans leur travail, et leur autonomisation ? Pourquoi leur rôle si fondamental dans tous les maillons de la chaîne de production alimentaire peine toujours à être reconnu ? Et si nous mettions en lumière, et prenions soin de celles qui nous nourrissent ?En écho au colloque organisé à Montpellier par la Chaire alimentation du monde de l'Unesco, consacrée au travail, et au prix social de notre alimentation, avec pour notre émission un regard sur les femmes, et leur rôle essentiel dans notre alimentation.«Quand le revenu des femmes augmente, tout le foyer en bénéficie ; cela permet d'améliorer l'accès aux soins, la scolarisation des enfants, les conditions d'existence du foyer.»Avec- Damien Conaré, secrétaire général de la Chaire alimentation du monde à l'Unesco- Jessica Pascal, chargée de mission partenariat Sahel auprès du CCFD Terre Solidaire Accueil - CCFD-Terre Solidaire- Alessandra Montagne, cheffe cuisinière cheffe des restaurants Nosso et Dana à Paris, et de l'épicerie Tempero. Pour aller plus loin- «Moi, agricultrice», de Delphine Prunault est accessible en ligne sur la chaîne LCP sur la chaîne Youtube : le coq chante, l'émission de Sayouba Traoré sur RFIautour de la militante altermondialiste indienne Vandana Shiva,- Les COFO, commissions foncières et villageoises.- Bondir.e. Programmation musicale- O Paraiso, de Lucas Santana- Cauri, d'Angelique Kidjo.
Dès le lever du jour, dans les villages et les villes, au champ comme en cuisine, elles sont là à planter, à cueillir, à récolter, à vendre, à transformer, à conserver, à élever, à cuisiner : les femmes nourrissent le monde, mais le monde le sait-il ? Selon la FAO, 3% soit près de la moitié des femmes actives dans le monde travaillent dans l'agriculture, parfois jusqu'à 70/80% dans certains pays africains, 14% d'entre elles seulement sont détentrices de leur terre. Quels freins concrets, sociaux, limitent encore les femmes dans leur travail, et leur autonomisation ? Pourquoi leur rôle si fondamental dans tous les maillons de la chaîne de production alimentaire peine toujours à être reconnu ? Et si nous mettions en lumière, et prenions soin de celles qui nous nourrissent ?En écho au colloque organisé à Montpellier par la Chaire alimentation du monde de l'Unesco, consacrée au travail, et au prix social de notre alimentation, avec pour notre émission un regard sur les femmes, et leur rôle essentiel dans notre alimentation.«Quand le revenu des femmes augmente, tout le foyer en bénéficie ; cela permet d'améliorer l'accès aux soins, la scolarisation des enfants, les conditions d'existence du foyer.»Avec- Damien Conaré, secrétaire général de la Chaire alimentation du monde à l'Unesco- Jessica Pascal, chargée de mission partenariat Sahel auprès du CCFD Terre Solidaire Accueil - CCFD-Terre Solidaire- Alessandra Montagne, cheffe cuisinière cheffe des restaurants Nosso et Dana à Paris, et de l'épicerie Tempero. Pour aller plus loin- «Moi, agricultrice», de Delphine Prunault est accessible en ligne sur la chaîne LCP sur la chaîne Youtube : le coq chante, l'émission de Sayouba Traoré sur RFIautour de la militante altermondialiste indienne Vandana Shiva,- Les COFO, commissions foncières et villageoises.- Bondir.e. Programmation musicale- O Paraiso, de Lucas Santana- Cauri, d'Angelique Kidjo.
Você está usando o açafrão ou cúrcuma da forma correta para ter o máximo dos seus benefícios? Não é só colocar pimenta na cúrcuma, pessoal, tem outras dicas interessantes que vou compartilhar. A cúrcuma também pode ser usada na forma de suplemento e fica a dúvida. Quando você deve pensar em suplemento e quando deve usar apenas o tempero? E quais os melhores tipos de suplementos de curcumina disponíveis hoje no mercado? Sem a menor sombra de dúvida, um dos maiores benefícios da cúrcuma é seu potente efeito anti-inflamatório. Ela pode tratar dores articulares, artrite, artrose, pode ajudar no tratamento de casos relacionados à trombose vascular e pode proteger pacientes que têm maior risco de desenvolver doenças cardiovasculares, já que ela reduz o estresse oxidativo, melhora o processo inflamatório e pode tratar o colesterol alto. Bem, neste vídeo, você vai saber tudo o que precisa sobre ela e ainda vai aprender algumas dicas para usar com sabedoria. Links de estudos sobre a Cúrcuma/curcumina: Estudos: https://www.thrombosisresearch.com/article/S0049-3848(10)00603-1/fulltext https://pubmed.ncbi.nlm.nih.gov/29052850/ https://pubmed.ncbi.nlm.nih.gov/10484074/ https://pubmed.ncbi.nlm.nih.gov/23832433/ https://pubmed.ncbi.nlm.nih.gov/31423805/ https://pubmed.ncbi.nlm.nih.gov/25046624/ https://pubmed.ncbi.nlm.nih.gov/16219905/ https://pubmed.ncbi.nlm.nih.gov/32713186/ https://europepmc.org/article/med/1496714 https://pubmed.ncbi.nlm.nih.gov/22407780/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003001/ https://www.cancerresearchuk.org/about-cancer/treatment/complementary-alternative-therapies/individual-therapies/turmeric https://pubmed.ncbi.nlm.nih.gov/19665995/ https://www.sciencedirect.com/science/article/pii/S0254627215300418 https://link.springer.com/article/10.1007/s10620-005-3032-8 https://pubmed.ncbi.nlm.nih.gov/29020971/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071279/ https://pubmed.ncbi.nlm.nih.gov/32319320/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358025/ https://www.tandfonline.com/doi/abs/10.1207/s15327914nc5502_2 https://pubmed.ncbi.nlm.nih.gov/29480523/ Seja membro deste canal e ganhe benefícios, conteúdo exclusivo, acesso ao grupo de Whatsapp e 2 lives exclusivas mensais: https://www.youtube.com/channel/UCRLKi_9gQNthwlKi70qi54g/join Conheça a Pós Graduação do Dr Alain - https://alaindutra.com/pos ⚠️AVISO LEGAL⚠️ A informação médica contida nesse vídeo é somente para fins de informação geral e não deve ser usada para qualquer finalidade de diagnóstico ou tratamento. Esta informação NÃO cria nenhuma relação médico-paciente e não deve ser usado como substituto de diagnóstico ou tratamento profissional. Por favor, consulte seu médico antes de tomar qualquer decisão sobre cuidados de saúde e NÃO pare nenhuma medicação sem o consentimento do seu médico. A Medicina é uma ciência em constante mudança, os vídeos são produzidos baseados nos Artigos Científicos mais recente até a data. De acordo com Art. 8º da Resolução CFM 1974/11 de Publicidade do Código de Ética Médica, os vídeos têm somente caráter de prestar informações de fins estritamente educativos. Dr. Alain Dutra -
Mais uma semana começando, e muita gente precisa se organizar e preparar receitas coringas para o resto da semana. Uma delas é o tempero caseiro de alho e sal. Por isso, no Alvorada Gourmet de hoje, Flavio Trombino passa o modo de preparo desse item essencial e muito utilizado. Confira! Ingredientes: 2 unidades de cebola grande 2 unidades de cabeça de alho 1 unidade de pimentão verde Meia xícara de chá de óleo 1 colher de sopa de sal See omnystudio.com/listener for privacy information.
Nesse episódio trazemos a rica história da Rita Angélica, mãe, esposa, filha e sócia-fundadora da Tempero da Casa. Desde de muito cedo, demostrou ter o espiríto empreendor de resiliência e a criatividade de inovar nos momentos mais decisivos. Nada melhor do que ouvir uma mulher empreendedora e inspiradora no mês do cuidado e do amor à vida. Uma homenagem da Treinacon para todas as mulheres. Gostou? Curte e Compartilhe! Inscreva-se no nosso canal: https://www.youtube.com/TreinaconNegociosEmpresariais/?sub_confirmation=1 Entre no nosso site: http://www.treinacon.net Instagram: https://www.instagram.com/treinacon Facebook: https://www.facebook.com/treinacon LinkedIn: https://www.linkedin.com/company/treinacon tags: empreendedorismo, empreendedorismo feminino, empreendedorismo digital, zona de conforto no empreendedorismo, evento de empreendedorismo, empreendedorismo aula, empreendedorismo materno, empreendedorismo de sucesso, empreender com leveza, empreendedorismo para mulheres, #inteligenciaemocional #empreendedorismo #exposed, leveza, empreendedorismodigital, empreendedor, empreendedora, mae empreendedora, mãe empreendedora, barbeiro empreendedor, como ser um empreendedor #mulherempreendedora #empreendedorismodigital
Pagãos do mundo com Petrucia Finkler do Brasil, que partilha entrevistas sobre tópicos de interesse como mitologia, magia, devoção e história. Em Outubro, vamos falar com Amanda Celli, a bruxa e bióloga criadora do Tempero de Bruxa – um projeto multi plataforma sobre Bruxaria, Magia Natural e Culinária Mágica. Vamos falar da aliança tão importante dos bruxos com o reino vegetal e também sobre a grande mãe Gaia que acolhe e nutre a todos nós.
Nesta quinta-feira, Silvana Oliveira entrevistou a produtora do festival tempero Bahia, Djanira Dias, que falou sobre o festival tempero Bahia
Neste episódio falamos sobre a restrição de alimentação e ingestão de líquidos, e o quanto isso pode impactar negativamente para o desenvolvimento sadio e respeitoso do cenário do parto e nascimento, transformando assim, a fome, no pior tempero. Como será que isso pode ter impactado no cenário de parto de Fernanda? Será que é só mais uma conduta violenta, ou tem algo além? . Conta para gente o que você achou no falandodevopodcast@gmail.com ou em nosso Instagram @falandodevopodcast. . Nossas indicações são: . Diretrizes Nacionais de Assistência ao Parto Normal - https://bvsms.saude.gov.br/bvs/publicacoes/diretrizes_nacionais_assistencia_parto_normal.pdf . Cuidados à mulher em trabalho de parto: Boas práticas o primeiro período - https://www.arca.fiocruz.br/bitstream/icict/29792/2/CUIDADO%20%C3%80%20MULHER%20EM%20TRABALHO%20DE%20PARTO_BOAS%20PR%C3%81TICAS%20NO%20PRIMEIRO%20PER%C3%8DODO.pdf . Movimentação e dieta durante o trabalho de parto: a percepção de um grupo de puérperas - https://www.scielo.br/j/tce/a/nKmdNKkYJ7WhWLXw4Vh8RZC/?lang=pt . Você pode nos mandar sugestões, dúvidas, críticas e elogios em: . instagram.com/falandodevopodcast falandodevo@gmail.com ⠀ . Nossas redes são: . Andreza Santana: instagram.com/maequeadvoga e twitter.com/DezaSantana . Bruna Bronzato: instragram.com/advogandocomfilhos . Bruna Thayses: instagram.com/brunathayses
Daniel Araujo é Sócio Fundador e Diretor Comercial da @otemperodacasa . Uma aula de empreendedorismo e vida de uma empreendedor, pai, filho e marido contando como conseguiu e ainda consegue atingir seus maiores objetivos. Gostou? Curte e Compartilha! Acompanhe nossas redes sociais para saber mais: Instagram: https://www.instagram.com/treinacon/ Youtube: https://www.youtube.com/channel/UCR-JghESQIHyJEX8VZRAohA Para dúvidas ou sugestões de temas? podcast@treinacon.net
Meditação de 04 de julho de 2022 Extraída do devocional Manancial Título: Tempero para a vida Texto: Lidiane Machado Leitura e Edição: Samuel Lima BG: "Santo, Santo, Santo", por Darlan de Souza
Jorge Natan recebe Fred Gomes e Arthur Muhlenberg para analisar triunfo no Maracanã diante do Cuiabá, o primeiro de Dorival Jr. Setorista atualiza situação sobre contratação do atacante do Benfica
“A Note of Gratitude” by Austin J. Price: A senior resident honors his grandmother and expresses gratitude to a doctor who had a long lasting influence on him and his family. TRANSCRIPT Narrator: “A Note of Gratitude” by Austin J. Price, MD-MPH (10.1200/JCO.21.01781) Mary Ann Richards-Elbrader was many things. Born in rural Kansas in 1936, she was a product of the pre-War Depression Era. That fact, I am sure, had an impact on the type of person she would become—a hard worker to a fault and a fiercely loyal family woman. She was the mother of five, the grandmother to 13 including me, and a friend to all, rarely knowing a stranger. Only a high school graduate herself, she believed wholly in the value of education, something that no other person could ever take away. Owing to that belief, all of her children earned college degrees, something that made her immensely proud. She was quick to anger and even quicker to apologize. Devoutly faithful, she taught her children to believe in something greater than themselves. On a more lighthearted note, she was known to lay back in the recliner after a hard day with a stiffly poured vodka. I recall the kindness ever present in her eyes, seen through large, clunky, 80's style frames and the lines on her face that easily divulged to the world she was someone who loved to laugh. The fact that she became a patient with cancer in 1995 is quite likely the least interesting thing about her. My grandmother's journey with cancer began, as many things did for her, in the service of others. She was a frequent blood donor. After giving blood once, she was found to be anemic and instructed to see her primary care doctor. The diagnosis came swiftly— colorectal cancer. From what I have been told, the goal initially was cure. I was very young and hardly able to grasp the nuances of her clinical course. Nonetheless, I know she had surgery and chemotherapy, and for a while after that, everything seemed fine. My mother and aunts recall a discussion when there was mention of age spots in her liver that would be monitored. That probably seemed harmless at the time, but it sounds so ominous to me now. Indeed after a 1.5-year remission, my grandmother experienced a roaring recurrence, this time in the liver. As tragic as it was, I share these details merely as a prelude to something wonderful. It was 1998, and my grandmother found herself seeking a second opinion at the University of Nebraska from a medical oncologist named Dr Tempero. As my family recalls, there was a clinical trial for patients with colorectal cancer metastatic to the liver ongoing at that time. My grandmother initially qualified but was soon disqualified for medical reasons. Despite that, our entire family quickly came to thoroughly appreciate this oncologist. What it was about her that resonated so deeply is difficult to express in words. In my mother's terms, it was her confident, no nonsense, but never cold, demeanor that provided assurance that she knew her stuff while still having her patients' best interests at heart. She was also very honest from the outset in a compassionate, preparatory way, without becoming bleak. Perhaps most striking, my mother recalls, was their last meeting in Omaha, when she explained that there was no more she could do from a medical prospective. There were tears in her eyes, but she did not cry. She exuded both empathy and resolve, which made her more human but no less professional. My grandmother succumbed to cancer on September 20, 1999. I was 8 years old. I never spoke to her specifically about Dr Tempero, but I remember hearing stories about that doctor in Omaha who was so acutely aware of the human experience. A decade later, I was about to start my freshman year of college. I had always been reasonably smart, fairly ambitious, and done well in school. However, as an 18-year-old, I shall admit that I was more preoccupied with the social aspects of college than I was with what might happen in 10 years. Slowly, I became more interested in the prospect of going on to medical school. Much of my early childhood had been fraught with my grandmother's illness and I recalled the various roles physicians had played in her life. My mother always told me, "If you are going to be a doctor, be like Dr Tempero.” I realized early on becoming such a physician would require much more than good grades and perseverance; it would require a constant commitment to being present, humble, and empathetic, without losing the confidence that allowed others to find comfort and value in my assessments. Ultimately, I decided that was a challenge I wanted and needed to pursue. With the unending support of my family and friends, I got into medical school and graduated in May 2019. I am now an internal medicine resident in San Francisco. My residency experience has been greatly different from what I anticipated. As the COVID-19 pandemic descended on our hospital, I found myself as an intern charged with facilitating end-of-life discussions through FaceTime, fully clad in personal protective equipment. Continually, I had to explain to families of the critically ill why they could not visit their loved ones. There was no instruction manual on how to have such conversations, but I know every day I channeled what I had garnered from my own family's experiences with the health care system. I am unsure if I succeeded in the ways that Dr Tempero did, but I have never stopped trying. In December 2020, I was triaging patients from the emergency department. While gathering the history on one patient, I asked “who is your oncologist?” When he replied, “Dr Tempero,” I froze. Surely it could not be the same doctor, the same one I had heard about since I was 8 years old? The one whose unique abilities I would always tried to emulate? When I left the room, it did not take much time on Google to realize it was. I shared portions of this story with my patient, who was extremely complimentary of her. That evening, when I got home, I called my mother to share this truly cathartic experience. Ultimately, it was she who implored me to personally reach out. I sat down at my desk and wrote her a note of gratitude. The following day I got an email notification while at work. I waited until I had a few minutes to read her response in privacy: Dear Austin, Your letter is, without a doubt, the most touching letter I have ever received. I know how busy you must be right now, and I was doubly honored to know that you took the time to write this thoughtful message. Thank you from the bottom of my heart. I have had the privilege of helping so many patients over the years and each one becomes a gift. I may not be able to turn the course of their disease but I can always make the journey easier. On a Wednesday evening in early May 2021, a little over 23 years after she was my grandmother's doctor in Omaha, I met Dr Tempero for the first time. I joined her and her husband at their apartment in San Francisco for a glass of wine. We discussed medicine, our mutual love of travel, and of course the unique situation that precipitated our meeting. I could easily perceive the qualities my family had always admired about her. She was interested in my story and my goals, but yet forthcoming about her life, family, and career. Her persona was welcoming, but yet demanded respect. Two hours later, she walked me downstairs and waited until my Uber arrived at her door. As I rode across the city, I contemplated the miraculousness of these events. I wished, as I always will, that I had more memories of my grandmother that did not center upon her illness, but the reality is I do not. What I do have is the memory of this encounter that has left me with a sense of inner peace and optimism, reassured that I am exactly where I am meant to be. I write this in gratitude to a doctor, who had no way of knowing her kindnesses would have such lasting influence. Of course, I also hope to honor my grandmother's legacy. I know she would be honored to see how her own misfortune somehow managed to be the genesis of such positivity in my life. I believe she would also challenge us all, as do I, to be like that doctor in Omaha. Dr. Lidia Schapira: Welcome to JCO's Cancer Stories: The Art of Oncology, brought to you by the ASCO Podcast Network, a collection of 9 programs covering a range of educational and scientific content and offering enriching insight into the world of cancer care. You can find all of the shows including this one at podcast.asco.org. I'm your host Lidia Schapira, Associate Editor for Art of Oncology and Professor of Medicine at Stanford University. With me today is Dr. Austin Price, a senior resident in internal medicine at California Pacific Medical Center, soon to be an infectious disease fellow at the University of Kansas. We'll be discussing his Art of Oncology article, “A Note of Gratitude”. Our guest has no disclosures. Austin, welcome to our podcast. Dr. Austin Price: Thank you very much. Thanks for having me. I'm happy to be here. Dr. Lidia Schapira: Let me start by asking if you are, in addition to a writer, also an avid reader? Dr. Austin Price: Yes, in the past at least I have been somewhat stymied by going into residency, but in the past, I liked to read a lot. Dr. Lidia Schapira: So, tell me a little bit about your past readings and maybe favorite authors or books, something you'd like to share with our listeners. Dr. Austin Price: I like to read about medical history. And so, one of my favorite books actually is by Dr. Paul Offit, and it talks about the early days of vaccines and how there was, I think it's called The Cutter Incident, but it's a great book. I may be misquoting the actual name, but great book. When I was in Baltimore, and doing my master's, he gave some guest lectures. And that's where I became acquainted with some of his work, I like reading that. So, those are the kinds of things that I really enjoy. And then I think, of course, I have always really enjoyed F. Scott Fitzgerald, even from high school, and Hemingway. Dr. Lidia Schapira: Very classically trained. Tell me a little bit about writing. Writing is a way of sharing an experience or perhaps processing a difficult encounter with a patient, is that something that you routinely do or have thought of? Dr. Austin Price: Yeah, it's definitely become something that's been more robust as I've gone through residency. I think part of that certainly had to do with the pandemic, and just not being able to be as close with people and have those personal relationships. And I found myself kind of cut off, maybe from a support system that I would have otherwise had, being in California with most of my friends and family in the Midwest. And so, I used writing as a way to kind of compartmentalize my feelings and my interactions with patients and to check in with myself. And I find that it's therapeutic and also enjoyable. Dr. Lidia Schapira: That's fantastic. Let's talk about the essay that you submitted and we published in Art of Oncology, which is a way of honoring the memory of your grandmother, who had cancer when you were a child, and also talks about your sense of vocation and this ideal that was held up to you by your family of aspiring to be as empathic and wise, as a doctor, who is an oncologist who helped your grandmother. Let's start a little bit with your grandmother's illness and how you remember that now that you are a physician. Dr. Austin Price: Yeah, certainly. I mean, I just remember as a child, her getting very sick, and finding out that she had cancer, and knowing that that was a bad thing, but not really knowing any of the details of it. As it turned out, she had colorectal cancer, and had surgery, for a short time she seemed okay. And then she got sick again, this time with metastatic disease to the liver. And of course, she was very sick then and ended up seeking out a second opinion from an oncologist who becomes the person in the story that I write about, in Omaha. At that time, there really wasn't anything that could be done to save her life, essentially. But the interactions that they had were very impactful to both her and the rest of our family. So much so that all through my life, my family members said, if you want to become a doctor, which I thought kind of early on, I did, that I should be like this particular person, Dr. Tempero. And so, she had just always been this kind of person on a pedestal, if you will. Dr. Lidia Schapira: Let's talk a little bit about the impact that Dr. Tempero and her consultation had on your family. Can you tell me a little bit more about how they talked about that particular meeting? Many of us who are in oncology and have been for a long time often talk about the fact that there can be a therapeutic relationship between the oncologist and the patient and the family that can actually help during difficult times and even through bereavement. But it's so interesting to me to hear you speak about it from the perspective of a family member. Tell me a little bit about how that relationship impacted the way the family understood the illness and how they went through their loss? Dr. Austin Price: I definitely think that there was a therapeutic relationship established. And I think in a way, Dr. Tempero managed to be preparatory in the sense that she knew that the outcome was likely not going to be good. I think she did that without ever being bleak or ever losing hope, in doing so she really kind of helped, in her own way, move us slowly towards accepting reality, and then learning how to move forward and enjoy the time that we had left together. I think all of my mom's siblings remember her in the same way, they really trusted her in such a robust way that her assessment that there really wasn't anything else medically that could be done, really helped them to come to terms with it and to refocus their goals, and those goals being to spend as much quality time with my grandmother that they could. Dr. Lidia Schapira: And as you've gone through your medical training, I imagine that they'll have to dangle this idea of this ideal doctor in front of you more than once. How have you interpreted or internalized this aspiration to also be wise, empathic and so kind to your patients? Dr. Austin Price: Yeah, it's definitely something that my mother in particular is always reminding me to do, because it's not always easy, as we all know. And there are times when I'm frustrated and tired and all those sorts of things. So, she and I've had many conversations where I'm maybe lamenting about feeling overworked or this or that. And she's always reminding me to be present and to realize that, although I'm tired that I'm oftentimes interfacing with people at bad points in their life. So, I always try to keep that at the forefront of my mind and try to decompress before each patient interaction, in hopes that I can be at least to some degree like Dr. Tempero was for my family. I'm sure that I don't always succeed in the ways that she did, but I hope that I do most of the time. Dr. Lidia Schapira: I assume Dr. Tempero would reassure you that even she may have a bad day or a bad hour in a day. Your essay has a moment of suspense and a twist in the plot when you find yourself now as a physician in an emergency room looking after a patient who tells you that their oncologist is none other than Dr. Tempero. Tell us a little bit about what that felt like? Dr. Austin Price: Well, I mean, it was just altogether shocking, honestly, because I had never met her and I really had never even Googled her name in the past. She was just always this person that my mother talked about so much. And then I had come to a kind of honor but I assumed for all I knew that she was still in Omaha. And so, when I heard this name, I thought, well, how many oncologists named Dr. Tempero are? Well, there's probably more than just her, but I immediately left the room and started to Google and realized, just quickly, that it was her or that I assumed that it was because she had done her training in Omaha at the University of Nebraska. It was shocking and emotional too, I will say. I immediately remember texting my mom and being like, oh my gosh, this patient just told me that Dr. Tempero was their oncologist. And I have to go back in there and finish the assessment because I kind of had to leave the room to just decompress a little. Yeah, it was a wonderful feeling and also just one of those moments where you're just like, life is so interesting in the way that you come into contact with people and in situations that are just so unique. Dr. Lidia Schapira: And then you reached out to her? Dr. Austin Price: I did. Yeah, my mom told me, she said, she may not have time to get back to you about this but you should at least reach out and explain how this made you feel. And thank her for the way that she treated our family and thanked her for the ways in which she or the idea of her has kind of impacted the type of physician that you aspire to be. Dr. Lidia Schapira: So, you wrote to her, and she wrote you back. What was that like and what happened after that? Dr. Austin Price: Well, I just remember being shocked that she wrote back so quickly. I know that she's incredibly busy. And so, I was very happy that she'd written back so quickly. Honestly, when it was written, this all happened at Christmas time. So, I wasn't able to be there because of COVID and working through the holidays. It was just the first time in 30 years that my mom hadn't seen me for the holidays. So, she was emotional about that. And so, getting to read Dr. Tempero's response to the family over FaceTime on Christmas, really was kind of like the best gift that they could have gotten. They really enjoyed it. That kind of helped to stifle the blow a little bit of me not being able to be there for the first time. Dr. Lidia Schapira: I'm just getting teary just thinking about that scene of you're reading this message to the family over FaceTime, and then talking Dr. Tempero invited you to meet her, and you had a long conversation, tell us a little bit or share with us what you feel is appropriate so that we can understand how important that reunion was for both of you? Dr. Austin Price: Yeah, sure. From the first response email, she said, 'I would like for us to get together and for us to meet in person when it's safe to do so', because when this interaction initially happened, none of us had been vaccinated yet, and so we're still in the throes of COVID and still petrified and all those things. And so, once we had been vaccinated, I reached out to her and said, I actually have started to write this essay, and I just wanted to know your thoughts on it. And she read it and she said, and this was many iterations ago when it wasn't as good as I think it is now, but she was like, 'Oh, I'm very much in support of this and I'm very honored, and by the way, we're vaccinated now and it's time for us to finally meet.' So, we did. It was great. I met her and her husband at their apartment in Mission Bay in San Francisco. We just had a lovely evening, had a glass of wine, some hors d'oeuvres, and just talked about this unique situation that had brought us together, and also talked a lot about my life and what I want to do in my career and my future. She was more interested in me than sharing so much about her life, but was very forthcoming when I would ask her questions as well, then also just had this kind of commanding aura, but welcoming at the same time, just very likable. I don't know how to explain it, other than that it was amazing and I was so thrilled to experience it. Dr. Lidia Schapira: I think you've explained it very well. It's a beautiful story for us to read, for all of us who have been in oncology for all these years, and those who are just starting, it's really inspiring. We think a lot about mentoring our students or junior faculty, but the idea that we in our clinical roles, can also have sort of in a way an indirect mentorship, relationship with or an influence with other young members of the families is really beautiful and moving. I thank you so much for having sent it to us and for sharing that experience. Is there something else, Austin, that you would like our readers and listeners to know about the essay itself, your family, or the intention that you had that brought you to not only write but share your writing so publicly? Dr. Austin Price: Yeah, I hope to honor my grandmother, because I think it's been interesting, this experience brought me a lot of joy, and I think it brought our family a lot of joy. The fact that that came from such a sad place and sad reality, I think is really great. For clinicians, it's just really important to realize how far-reaching our interactions with patients can be because we are seeing them, oftentimes, really in bad times of their lives, times that they're going to remember for a long time. And so, we can then be remembered in kind of good ways and bad. I think it's so unique in the situation that in an interaction that Dr. Tempero had with my family, nearly a quarter-century ago, it only took the mention of her name, to bring back this whole flood of memories and spawn all of this. I think that's really cool and something that we should always be cognizant of. We have very far-reaching impacts for our patients. I just think that that's cool, and a good thing to be reminded of. Dr. Lidia Schapira: I think it's very cool too and I thank you so much, Austin, for sharing your essay and for taking part in this conversation. Dr. Austin Price: Thank you for having me. Dr. Lidia Schapira: Until next time, thank you for listening to this JCO's Cancer Stories: The Art of Oncology Podcast. If you enjoyed what you heard today, don't forget to give us a rating or review on Apple podcasts or wherever you listen. While you're there, be sure to subscribe so you never miss an episode of JCO's Cancer Stories: The Art of Oncology Podcast. This is just one of many ASCOs podcasts. You can find all of the shows at podcast.asco.org The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity or therapy should not be construed as an ASCO endorsement.
O Evangelho de hoje nos apresenta a tocante cena da apresentação do Senhor no Templo, onde o Menino Jesus, reconhecido pela profetisa Ana como o libertador de Israel, faz uma de suas primeiras epifanias públicas ao povo que viera resgatar de seus pecados e infidelidades. Assista à homilia do Padre Paulo Ricardo para esta quinta-feira, dia 30 de dezembro, e, a exemplo de Santa Ana e do justo Simeão, apertemos o Menino Jesus ao nosso peito, sabendo que quem temos nos braços é o próprio Deus que com mão potente sustenta todo o universo. --- Send in a voice message: https://anchor.fm/jlio4/message
Ana Markl e a psicóloga-sexóloga Tânia Graça conversam sobre ciúme: as origens desse sentimento e como pode arruinar ou ajudar a renovar o amor e o desejo numa relação.
Learn in today's podcast a dialog using a lot of the prepositions "sem" and "com". Today's transcript can be accessed in : coming soon But, if you are an intermediate Portuguese student looking for more advanced content, we recommend you this podcast: https://anchor.fm/portuguesewitheli --- Send in a voice message: https://anchor.fm/readbrazilianportuguese/message
Hoje, atravessamos o Atlântico e vamos parar em Portugal pra conhecer a história da Filomena Francisco e aprender sobre a relação de amor do Erotismo no mundo dos Negócios: essa é uma história de coragem e enfrentamento regada com muita doçura e forca. Espero que você goste! --- Send in a voice message: https://anchor.fm/paulatirapelli/message
Freelance coach and Facebook group hipster, Emma Cossey (she/her), shares her thoughts and tips for Facebook groups whether you're growing your own or getting involved in other people's. We talk about the shift from community to sales, common Facebook group problems and how to be a good group member.Emma Cossey is a coach for freelancers, with over a decade of freelancing experience under her belt. Previous clients have included The Discovery Channel, Macleans, Shell, Dorothy Perkins, ParentDish UK, Tempero, Camelot (National Lottery), Groupon and The Times online. She lives in Bracknell with her husband Pete and their son Oscar.You can find Emma on Instagram or in her free Facebook group. You can also listen to her on her podcast and check out her services through her website.I hang out on Instagram.Join Alexis' free Facebook group.Find everything you need to know about using social media as a small business on my website.Voice over by Hawke Wood.Support the show (https://www.patreon.com/socialmediaforhumans)
Por Pr. Alcimou Barbosa. https://bbcst.net/Z7488
Por Pr. Alcimou Barbosa. https://bbcst.net/Z7488
Por Pr. Alcimou Barbosa. https://bbcst.net/Z7488
Por Pr. Alcimou Barbosa. https://bbcst.net/Z7488
Por Pr. Alcimou Barbosa. https://bbcst.net/Z7488
Por Pr. Alcimou Barbosa. https://bbcst.net/Z7488
Por Pr. Alcimou Barbosa. https://bbcst.net/Z6419