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Send us Fan Mail Why do smart teams still struggle?They have talented people.They have the right skills.They have the strategy.And yet, something is still not working.In this episode, Marco explores why future skills alone are not enough. Analytical thinking, creativity, resilience, and leadership only create impact when people know how to work together.Because skills do not fail.People working together do.We explore:• Why the space between people is where teams often struggle• How perception shapes the way we interpret others• Why slowing down before responding is a critical leadership skill• How intercultural agility helps teams create a shared cultural space• Why strong teams are built through behaviors, not just values on a wallThe future does not belong to teams with the most skills.It belongs to teams that know how to unlock those skills together.Learn more about KnowledgeWorkx:https://www.knowledgeworkx.com/Explore intercultural conversations:https://interculturalquestions.com/Discover intercultural agility:https://www.interculturalagility.com/#InterculturalAgility #CulturalIntelligence #Leadership #FutureOfWork #GlobalLeadership #HighPerformingTeams #TeamCulture #CrossCulturalLeadership #KnowledgeWorkx-- Looking for a book to take your cultural agility to the next step, check out the Ultimate Intercultural Question Book brought to you by KnowledgeWorkx.com
In this episode, we talk about the relational paradigm in political philosophy. Made famous by Iris Marion Young, developed later by Elizabeth Anderson, this view of what equality is all about presents a puzzle for the class conscious. It says that the point of equality is to live in a society of equals. Its proponents skewered famous analytical Marxists for having a reductive and economistic view of justice. Was this fair? Join us to find out. This is just a short teaser of the full episode. To hear the rest, please subscribe to us on Patreon:patreon.com/leftofphilosophyReferences:Elizabeth Anderson, “What's the Point of Equality?” Ethics 109 (1999): 287-337.Samuel Scheffler, “What is Egalitarianism?” Philosophy and Public Affairs 31(2003): 5-39.Iris Marion Young, Justice and the Politics of Difference. Princeton University Press, 1990. Music:“Vintage Memories” by Schematist | schematist.bandcamp.com“My Space” by Overu |https://get.slip.stream/KqmvAN
In this final episode of the ICH Quality series, we walk through the most important concepts in ICH Q14 and how they fit into the broader ICH quality framework.Rather than reviewing the guideline section by section, this episode focuses on the ideas that are most useful in practice: Why does ICH Q14 start with the Analytical Target Profile (ATP)? How is it different from ICH Q2? How do you develop analytical procedures using a science- and risk-based approach? And what does all of this have to do with ICH Q12 and lifecycle management?One quick note: at the time of recording, ICH Q14 remains under public comment, so some details may evolve before the final version is adopted.Chapters00:00 – Intro and ICH Q14 vs. Q201:08 – The Analytical Target Profile (ATP)04:16 – The Analytical Procedure Lifecycle05:32 – Risk-Based Development and Enhanced Approaches06:20 – Where ICH Q2 Fits: Validation08:04 – Connecting Q14 to ICH Q12 and Lifecycle Management09:22 – Closing the ICH Quality SeriesIn this episode, we cover:• Why ICH Q14 exists• The difference between ICH Q14 and ICH Q2• What an Analytical Target Profile (ATP) is• ATP examples and performance criteria• Technology selection and fit-for-purpose methods• The analytical procedure lifecycle• Risk assessments and enhanced development approaches• Multivariate experiments and DOE concepts• Analytical procedure control strategies• Validation and the role of ICH Q2• Lifecycle management of analytical procedures• The connection between ICH Q14 and ICH Q12• Why understanding matters more than simply checking a boxIf you've followed along through the ICH Quality series, one of the themes that keeps showing up is that quality isn't something you test into products at the end. Whether we're talking about Q8, Q9, Q10, Q12, or now Q14, the emphasis continues to shift toward building knowledge, understanding risk, and using that understanding throughout the lifecycle.Subhi Saadeh is the Founder and Principal at Let's Combinate, where he helps teams develop and control drug-device combination products by aligning quality systems, development, and regulatory expectations across drug and device domains. He is a consultant, auditor, trainer, speaker, and host of the Let's Combinate podcast, with experience across companies including Pfizer, Gilead, and Baxter supporting vaccines, biologics, generics, and combination products.
Eric the Analytical Iowan is back in the house. So much to cover and he's just the guy to cover it. Let's get into it.
Eric the Analytical Iowan is back in the house. So much to cover and he's just the guy to cover it. Let's get into it.
Welcome back to the Jack Westin MCAT Podcast with Mike and Molly! We just finished amino acids and protein structure. Now it is time for one of the most feared topics in MCAT biochemistry: analytical and separation techniques.If you have ever stared at a Western blot figure in a passage and had absolutely no idea what you were looking at, this episode is exactly what you need. Mike spent years running these experiments in the lab and still has the PTSD to prove it. Together, Mike and Molly break down every technique you need to know, from the foundational logic of electrophoresis all the way to interpreting banding patterns on a gel.Get started with our resources!
How does a math and applied science degree from UCLA lead to a career launching national products every five weeks at Taco Bell? In this episode, marketing strategist Lidija Davidson explains the "Analytical Marketer" mindset, showing how data can uncover deep consumer insights that drive real innovation. We also dive into the true heart of branding, how a company's origin story and brand purpose are far more critical to success than just a logo or a tagline.Lidija is a marketing consultant and the owner of Sift, Cipher, and Bloom advertising and marketing agency.
(0:00) Palo Alto Networks CEO Nikesh Arora joins the Besties! (0:47) Claude Mythos found years of vulnerabilities in Palo Alto's code in weeks (5:15) Are cyber defenders losing the race against AI attackers? (6:50) Analytical SaaS is dead, so what survives the AI wave? (14:06) If models become a utility, where will the money be made? (20:35) Armchair CEO: Nikesh rates Waymo, Google, and OpenAI (28:22) Palo Alto's M&A playbook and the path to $1 trillion Thanks to our partners for making this possible! EY - AI ambition isn't enough. EY.ai Value Blueprints move organizations beyond pilots embedding measurable business value by design. https://www.ey.com/en_us/services/ai/value-blueprints?WT.mc_id=3501320&AA.tsrc=sponsorship NYSE - Thank you to our partner, the New York Stock Exchange - a modern marketplace and exchange for building the future. It all happens at the NYSE. https://www.nyse.com Plaud - Never miss a moment. Plaud, our official wearable AI note-taking partner at All-In Liquidity Summit, captured every insight. https://www.plaud.ai Follow Nikesh: https://x.com/nikesharora Follow the besties: https://x.com/chamath https://x.com/Jason https://x.com/DavidSacks https://x.com/friedberg Follow on X: https://x.com/theallinpod Follow on Instagram: https://www.instagram.com/theallinpod Follow on TikTok: https://www.tiktok.com/@theallinpod Follow on LinkedIn: https://www.linkedin.com/company/allinpod Intro Music Credit: https://rb.gy/tppkzl https://x.com/yung_spielburg
Ben Burgis is joined by Michael Lazarus (author of "Absolute Ethical Life: Aristotle, Hegel and Marx") and Matt McManus (who needs no introduction to GTAA fans) for a fun three-way exchange on "analytical Marxism" (the tradition Ben works in), Michael's more Hegel-inflected version of Marxism, and Matt's sympathies with both sides.Order Michael's book:https://www.sup.org/books/politics/absolute-ethical-lifeFollow Michael on Twitter: @Mblaz39Follow Matt on Twitter: @MattPolProfFollow Ben on Twitter @JacobinBen [NOTE: The previous account was hacked!]Follow GTAA on Twitter: @Gtaa_ShowBecome a GTAA Patron and receive numerous benefits ranging from occasional patron-exclusive content to access to the GTAA Discord to our undying love and gratitude for helping us keep this thing going:patreon.com/benburgisRead the weekly philosophy Substack:benburgis.substack.com
Ken Carman and Anthony Lima discuss the heavy scrutiny on Cavaliers coach Kenny Atkinson after his "analytical win" comments went viral. They also examine the logic behind a potential Myles Garrett trade and take listener roasts during the "Coming in Hot" segment. 01:50 - Myles Garrett Trade Debate 06:49 - Evaluating Quarterback Markets 18:12 - Atkinson's Meme Pressure 28:37 - LeBron Scenarios and Callers 34:55 - Coming In Hot Segment
What happens when the ultimate spreadsheet brain meets the ultimate anabolic heart? In this episode of Spirit of the Deal, we're breaking down the recent sit-down between Alex Hormozi and Tony Robbins. While the rest of the internet was busy pulling out marketing tactics and funnel hacks, we're looking at the actual juice—the psychology, the ethos, and the stark contrast in their operating systems. We explore the "Dark Engine" of push motivation, the trap of sacrificing happiness just to be "useful," and why a comfortable background can sometimes force you to manufacture a hollow drive. Tying it all back to The Science of Getting Rich and Marianne Williamson's Law of Divine Compensation, the reality is simple: if you put out mechanical, transactional energy, you get a highly transactional bank account. Stop operating strictly out of duty. Tune in to find out how to shift from your "Analytical" brain to your "Anabolic" heart, and why finding a "pull" motivation—an anchor greater than yourself—is the only way to avoid winning the game but losing your soul. In this episode, we cover: The Vintage, Vineyard, and Varietal: Why your background dictates your drive. The Dark Engine: Building an empire on anger vs. contribution. The Trap of "Useful": Why Hormozi's "f*ck happiness" mantra leads to apathy. Push vs. Pull Motivation: Why willpower always runs out, and how to find the anchor that pulls you forward. Analytical vs. Anabolic: Choosing which version of yourself gets to negotiate your deals. Resources Tony Robbins Alex Hormozi The Science of Getting Rich by Wallace D. Wattles Marianne Williamson's Law of Divine Compensation
Eric the Analytical Iowan is back with us on the program. We cover it all and Eric is just the guy to help us. Let's get into it.
Eric the Analytical Iowan is back with us on the program. We cover it all and Eric is just the guy to help us. Let's get into it.
Cavs head coach Kenny Atkinson said his team won 2 out of 3 games "analytically." ESPN Cleveland's Aaron Goldhammer joins to discuss that and the Browns QB situation. Also, would this Knicks title be the biggest in the history of New York? Plus, how do the Thunder bounce back in game 5? Learn more about your ad choices. Visit podcastchoices.com/adchoices
Cavs head coach Kenny Atkinson said his team won 2 out of 3 games "analytically." ESPN Cleveland's Aaron Goldhammer joins to discuss that and the Browns QB situation. Also, would this Knicks title be the biggest in the history of New York? Plus, how do the Thunder bounce back in game 5? Learn more about your ad choices. Visit podcastchoices.com/adchoices
Eric the Analytical Iowan is back with us on the program. We go through it all. Let's get into it.
Eric the Analytical Iowan is back with us on the program. We go through it all. Let's get into it.
Process Analytical Technology (PAT) has evolved from a niche troubleshooting tool into a strategic necessity—but most companies still implement it too late. Dr. Stanislav Kazakov from Thermo Fisher Scientific reveals why starting PAT early can mean the difference between scaling success and costly manufacturing failures.Discover how real-time process insights, AI-driven chemometrics, and strategic implementation are reshaping quality control from lab to commercial scale across pharma and biotech.----------------------This episode is supported by Thermo Fisher Scientific. partners across the drug lifecycle to accelerate discovery, scale manufacturing, and ensure compliant release. Our analytical and process technologies support pharmaceutical and biotech teams from research and formulation through commercial manufacturing and quality control. With integrated instrumentation, workflow solutions, and expert service, we help protect yield, ensure data integrity, and deliver therapies to patients with confidence.----------------------Visit www.qualistery.com for live free webinars for GxP professionals, to stay on top of the latest industry trends.
in this reflection I deal with repressed and complicated grief regarding Mother's Day. Supporting themes: Inhibited/ masked grief; hypo- arousal; Alexithymia; Analytical safety. Trigger warning: There is a lot of sadness and a noticeable state of crying. Listen with care. Typology: INTJ; Enneagram 8; ESFJ; Enneagram 1
Eric the Analytical Iowan is back on the program. Every day some sh** happens and Eric is here to break it all down. Let's get into it.
Eric the Analytical Iowan is back on the program. Every day some sh** happens and Eric is here to break it all down. Let's get into it.
Eric the Analytical Iowan is back on the program. Eric breaks it all down for us. Let's get into it.
Eric the Analytical Iowan is back on the program. Eric breaks it all down for us. Let's get into it.
Eric "The Analytical Iowan" is back with us on the program. As always, we had a great conversation. Eric always breaks it down. Let's get into it.
Eric "The Analytical Iowan" is back with us on the program. As always, we had a great conversation. Eric always breaks it down. Let's get into it.
Jeehae Lee, founder and CEO of Sportsbox.ai, joins the Moneyball team to explore Rory McIlroy's Masters victory while analyzing how advanced motion capture, data analytics, and AI are reshaping player development, performance evaluation, and talent identification in golf. Hosted on Acast. See acast.com/privacy for more information.
How does one engineer run 40,000 people with 10 daily numbers, zero hobbies, and a $1 billion bet he made in his first year as CEO? Mario Harik is the CEO of XPO, one of the largest trucking companies in the world. He started as employee #3, learned from Brad Jacobs (who built eight multibillion-dollar companies from scratch), and now leads 40,000 people with a management style shaped by engineering discipline, frontline feedback, and a deep belief in human potential. Mario shares how he uses real-time data and second-derivative thinking to make decisions, how he hires and develops A players (and the gut test that tells you who isn't one), how he runs meetings that surface the best thinking from the most junior person in the room, and why ego, complacency, and small goals quietly cap everything. Enjoy! ----- Timestamps: (00:00:00) Defining ego and the importance of continuous learning (00:00:19) How an engineering mindset translates to business leadership (00:01:58) Applying engineering frameworks to CEO-level strategy and execution (00:03:38) Letting go of perfection and understanding how people operate (00:05:14) Lessons from working with Brad Jacobs and thinking big (00:07:13) Building strong teams and the importance of feedback loops (00:08:18) Evaluating talent: skill, work ethic, and collegiality (00:10:51) Disagreement vs consensus and decision-making in teams (00:12:50) Service-first strategy and improving customer experience (00:16:21) Running the business through KPIs, data, and real-time systems (00:19:41) Learning from frontline employees and feedback loops (00:22:35) Using technology and AI to track performance and reduce errors (00:28:35) Coaching employees through data-driven performance insights (00:29:30) Structuring effective meetings with data and ranked input (00:32:36) Pre-meeting preparation and leveraging team intelligence (00:34:29) Identifying and developing talent within the organization (00:39:48) Hiring frameworks and assessing candidates deeply (00:47:30) Early life experiences and how they shape perspective (00:49:27) Analytical approach to risk and decision-making (00:50:56) Capital allocation and the Yellow bankruptcy acquisition (00:55:31) Turning strategy into execution through financial tracking (00:59:23) A/B/C player framework for evaluating talent (01:02:12) Creating a high-performance environment through belief and feedback (01:04:18) Evolving leadership style and giving effective feedback (01:07:33) Core levers of value creation: people, capital, and time ------ Newsletter: The Brain Food newsletter delivers actionable insights and thoughtful ideas every Sunday. It takes 5 minutes to read, and it's completely free. Learn more and sign up at fs.blog/newsletter ------ Follow Shane Parrish: X: https://x.com/shaneparrish Insta: https://www.instagram.com/farnamstreet/ LinkedIn: https://www.linkedin.com/in/shane-parrish-050a2183/ Follow Mario Harik: LinkedIn: https://www.linkedin.com/in/marioharik/ XPO: https://investors.xpo.com/board-member/mario-harik/ ------ Thank you to the sponsors for this episode: +Granola AI, The AI notepad for people in back-to-back meetings: https://www.granola.ai/shane Check out the Granola Notes. +CoinShares: Delivering Reason to Digital Asset Investing. https://coinshares.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Cara Lee Barker is an international keynote speaker and visionary artist. She served as an Army nurse during the Vietnam era at Walter Reed Hospital. She has a Master's degree in nursing from the University of Washington and a Ph.D. in Clinical Psychology from Union Institute and University in Ohio. Her post-doctoral work was completed in Zurich as an International Diplomat and a Jungian Analyst. She was a columnist for HuffPost for five years and is the author of three books: World Weary Woman; The Love Project; and her latest release, Nightlight: My Soul Calling, Body Listening, Heart Speaking. "After I completed my PhD in clinical psychology, I began working in the so called 'human potential movement.' People wanted to dig deeper into who they really are on every level: spiritual, emotional, intellectual, physical and social. I loved doing that work and would have done it for free! I did my post-doctoral work in Zurich as an International Diplomat and Jungian Analyst. After reading Carl Jung's book–The Symbolic Life–I quickly realized the vital importance of dreams in helping people discover their inborn talents. I continue to work with clients, which uses my best talents, while I devote an increasing amount of time writing. My favorite life lesson from my very supportive parents: 'Lean into the thing you are trying to resist. Always lean in.'"
Eric, the Analytical Iowan is back on the program and none too soon. There's so much happening it's hard to keep it all straight. Well, Eric is here to straighten us out. Let's get into it.
Eric, the Analytical Iowan is back on the program and none too soon. There's so much happening it's hard to keep it all straight. Well, Eric is here to straighten us out. Let's get into it.
Last week at York University in Toronto, there was a panel to pre-launch a book of essays called "Analytical Marxism and Democratic Socialism in the 21st Century: Revisitng G.A. Cohen" co-edited by Ben Burgis and Matt McManus. Contributors Les Jacobs and Christine Sypnowich spoke first, then Matt and Ben. Q&A includes some spicy exchanges on dialectics and whether analytical Marxism is too academic to be of much use to the workers' movement. In this episode, Ben starts with some context on Cohen's life and the major themes of the work and then we play the full video of the panel. At the end, Ben comes back to chat a bit more about the trip to Toronto and the GTAA episode schedule going forward.Prices in academic publishing being what they are, we can't exactly tell you to go out and buy this thing, but if you want to get your library to order a copy, here's the link for that;https://www.amazon.com/Analytical-Marxism-Democratic-Socialism-Century/dp/3032028930Prof. Sypnowich's website:https://www.christinesypnowich.com/Prof. Jacobs's profile at York:https://profiles.laps.yorku.ca/profiles/jacobs/Follow Matt on Twitter: @MattPolProfFollow Ben on Twitter: @BenBurgisFollow GTAA on Twitter: @Gtaa_ShowConsider donating to Andy's GoFundMe so he can replace his computer and fully go back to doing what he does best:https://www.gofundme.com/f/help-andy-get-back-to-creating-art-jtwetBecome a GTAA Patron and receive numerous benefits ranging from occasional patron-exclusive content to access to the GTAA Discord to our undying love and gratitude for helping us keep this thing going:patreon.com/benburgisRead the weekly philosophy Substack:benburgis.substack.com
This lecture discusses key ideas from the 20th century philosophical short story writer, essayist, and poet Jorge Luis Borges's essay "The Analytical Language Of John Wilkins" which can be found in his collection Other Inquisitions. It explains the idea behind this rather utopian scheme to remodel language along completely rational and systematic lines in his work An Essay towards a Real Character and a Philosophical Language . He also compares Wilkins' project with a classification listing of animals in a fictional "Celestial Emporium of Benevolent Knowledge", and with a classification scheme of the Bibliographical Institute of Brussels. As a side-note, Michel Foucault famously incorporated and commented on Borges' fictional list of animals in his work The Order Of Things. To support my ongoing work, go to my Patreon site - www.patreon.com/sadler If you'd like to make a direct contribution, you can do so here - www.paypal.me/ReasonIO - or at BuyMeACoffee - www.buymeacoffee.com/A4quYdWoM You can find over 4000 philosophy videos in my main YouTube channel - www.youtube.com/user/gbisadler Get Borges' Other Inquisitions here - https://amzn.to/4br9pul
In this JCO PO Article Insights episode, host Jordan Goldstein summarizes the article, "Generic Protocols for Analytical Validation of Tumor-Informed Circulating Tumor DNA Assays for Molecular Residual Disease: The Blood Profiling Atlas in Cancer's Molecular Residual Disease Analytical Validation Working Group Consensus Recommendation" by Baden et al. TRANSCRIPT
Eric the Analytical Iowan stops in on the Rational Boomer Podcast. Eric breaks it all down for us. Let's get into it.
Eric the Analytical Iowan stops in on the Rational Boomer Podcast. Eric breaks it all down for us. Let's get into it.
In this episode of the Oncology Brothers podcast, we were joined by two international experts — Professor Gary Tse, a pathologist from the Chinese University of Hong Kong, and Dr. Carlos Barrios, a medical oncologist from Brazil — to unpack the evolving landscape of HER2 testing in breast cancer. What was once a binary positive or negative classification has now expanded to include HER2-low and HER2-ultra-low, opening the door to new treatment options for the majority of breast cancer patients. Listen us on: Spotify: https://open.spotify.com/show/31BXhY9FM4gPWG10WgE11o Follow us on social media: X/Twitter: https://twitter.com/oncbrothers Instagram: https://www.instagram.com/oncbrothers Website: https://oncbrothers.com/ Key topics discussed included: How HER2 classification has evolved from a binary result to a continuous spectrum including HER2-low and HER2-ultra-low, driven by the efficacy of antibody drug conjugates like T-DXd Pre-analytical challenges in metastatic settings including tumor heterogeneity The role of IHC, ISH, NGS, and liquid biopsy in HER2 assessment, and how each tool fits into clinical practice. The importance of multidisciplinary collaboration between pathologists and oncologists to ensure accurate interpretation and optimal treatment selection. Join us for this expert discussion on one of the most clinically impactful topics in breast oncology today. Don't forget to like, subscribe, and check out our other episodes for more insights on oncology! #HER2, #BreastCancer, #BiomarkerTesting, #PrecisionOncology, #OncologyBrothers
If you lead through the CliftonStrengths talent theme of Analytical, (or you know someone who does), this is the episode for you! Today's Strength Snapshot is Analytical The Analytical talent theme is driven by logic, evidence, and clarity. People with this strength are naturally objective, questioning, data-driven, and numbers-oriented. At its core, Analytical is about understanding how things actually work. These individuals instinctively look for patterns, causes, and proof. They don't accept ideas at face value. They test them. Analytical thinkers often describe themselves as scientific, skeptical, and dispassionate. What motivates them most is reliable information. They love facts, evidence, and discovering patterns in data. They feel energized when ideas can be supported, measured, and verified. When This Strength Is Thriving When Analytical is operating at its best, it brings grounded reasoning and thoughtful precision to any situation. This strength helps simplify complexity, think through multiple variables, and approach decisions logically and objectively. Analytical talent often shows up through roles like scientist, observer, measurer, fact finder, or logician. These individuals provide clarity when situations feel confusing. They slow things down just enough to ensure decisions are based on reality, not assumptions. Their thinking builds trust because others know conclusions are backed by evidence. To close, here's a simple 5-minute experiment to try in the next 24 hours… Choose one decision you're facing. Write down the facts you know, the facts you need, and one assumption you might be making. Then gather just one missing piece of information before deciding. Notice how clarity increases as evidence replaces uncertainty. Well, that's a wrap for today's episode. What small action can you take to show up at your best, given where you're starting today?
Cognitive neuroscientist Phillip Campbell explains how leaders can improve focus, adaptability, and strategic thinking by strengthening their brain skills. In this episode of On the Brink with Andi Simon, he explores "fluid thinking," the neuroscience behind change, and why developing cognitive adaptability is essential in the age of AI. Summary In this episode of On the Brink with Andi Simon, cognitive neuroscientist and executive brain coach Phillip Campbell shares powerful insights on how our brains shape our ability to lead, adapt, and innovate. Drawing on decades of research and coaching experience with Fortune 500 executives, Campbell explains why most change initiatives fail, how subconscious brain habits influence our thinking, and why "fluid thinking" is essential in the age of AI. As technological disruption accelerates, leaders who strengthen their brain skills—focus, adaptability, strategic thinking, and creativity—will be better prepared to thrive in uncertainty. This conversation explores how we can literally rewire our brains to improve performance, resilience, and success in a rapidly changing world. Rewiring the Brain for Success in the Age of AI: Insights from Cognitive Neuroscientist Phillip Campbell How do leaders adapt when change is happening faster than ever before? In this episode of On the Brink with Andi Simon, I spoke with Phillip Campbell, a cognitive neuroscientist, executive brain coach, and CEO of enigmaFit . His work focuses on something many leaders overlook: the way our brains are wired to resist change, even when we know intellectually that change is necessary. Campbell has spent more than 25 years coaching Fortune 500 executives and entrepreneurs around the world. His mission is to help leaders improve their brain skills, adaptability, and cognitive performance—capabilities that are increasingly critical in an era defined by artificial intelligence and constant disruption. Why Technology Initiatives Often Fail Campbell's journey began with a fascinating insight. Early in his career, he discovered research showing that 70% of technology implementations fail—not because of the technology itself, but because of human resistance to change. Organizations often invest heavily in systems and tools but overlook the most important element: the human brain. Campbell realized that successful transformation requires more than training people on new tools. Leaders must understand how individuals think, process information, and respond to uncertainty. When organizations align technology with how people actually work and think, adoption improves dramatically. This insight led him to develop his executive coaching firm, enigmaFit, and the TRACER methodology, which focuses on rewiring the brain to improve leadership performance. The Power of "Fluid Thinking" At the center of Campbell's work is the concept of fluid thinking. Fluid thinking is the brain's ability to adapt, solve new problems, and respond creatively to unfamiliar situations. It differs from what psychologists call crystallized knowledge—the facts and information we already know. For example: Crystallized knowledge: remembering the capital of France. Fluid thinking: solving a problem you've never encountered before. In today's fast-changing world, fluid thinking is becoming far more important. As Campbell explains, AI is transforming work by taking over routine cognitive tasks. That means humans must rely increasingly on adaptability, creativity, and strategic thinking. The Ten Subconscious Brain Habits Campbell identifies ten subconscious thinking habits—also called brain skills—that determine how effectively we think and perform. These brain habits influence abilities such as: Focus and attention control Strategic thinking Analytical thinking Creativity and innovation Adaptability and flexibility Leadership and decision-making One of the most surprising findings from Campbell's work is that 90% of executives have only low to moderate focus thinking. In other words, many leaders struggle with distraction and attention management. Modern workplaces—with constant emails, messages, and digital notifications—make the challenge even greater. When leaders strengthen their focus thinking, however, they often gain an extra hour of productive time each day and experience far less mental fatigue. Why Habits Drive Leadership Performance From an anthropological perspective, this insight is powerful. Human behavior is deeply shaped by habit and subconscious patterns. Campbell emphasizes that simply telling someone to "be more strategic" or "think more creatively" rarely works. That's because conscious intention cannot override subconscious brain habits. Instead, the brain must be trained through deliberate practice. This is similar to learning how to drive a car. At first, driving requires intense concentration. Over time, repeated practice builds neural pathways until driving becomes automatic. The same principle applies to leadership thinking. Through structured exercises and cognitive training, individuals can literally rewire the brain's neural architecture. Brain Capital in the Age of AI Campbell's work aligns with a growing global conversation about "brain capital." Organizations are beginning to recognize that their most valuable asset is not simply technology or intellectual property—it is the cognitive capability of their people. According to research highlighted by the World Economic Forum, brain capital includes: Brain health (mental well-being) Brain skills (thinking abilities) Companies that invest in strengthening both will have a significant advantage in an AI-driven economy. Building a Brain Ready for the Future The pace of change in today's world can create stress, anxiety, and burnout. Many professionals feel overwhelmed by the constant pressure to adapt. Campbell's message is ultimately optimistic. By strengthening focus, analytical thinking, creativity, and adaptability, individuals can build resilient brains capable of thriving in uncertainty. In other words, the future belongs not just to those with the most knowledge—but to those with the most adaptable minds. To learn more about Phillip Campbell and his work:Phillip's profile: linkedin.com/in/phillipcampbell001 Website: enigmafit.com Connect with me: Website: www.simonassociates.net Book Website: www.andisimon.com Email: info@simonassociates.net Learn more about our books here: Rethink: Smashing the Myths of Women in Business Women Mean Business: Over 500 Insights from Extraordinary Leaders to Spark Your Success On the Brink: A Fresh Lens to Take Your Business to New Heights Now--it is time to share our new book with our listeners. Rethink Retirement: It's Not The End--It's the Beginning of What's Next. On Amazon and soon in your local bookseller. Rethink Retirement: The Workbook
In this episode of Let's Combinate, Subhi Saadeh speaks with Jen Riter about analytical method validation for drug device combination products. The discussion explores how traditional drug analytical validation under ICH Q2 differs from validating functional and mechanical performance methods used for combination products. These methods often require an engineering mindset that incorporates measurement system analysis (MSA), gage R&R studies, and the use of fabricated surrogate standards when devices cannot be reused for testing.They also discuss platform test methods and how standards such as ISO 11040 and other ISO references can serve as starting points for method development. The conversation touches on the evolving alignment between ISO based device methods and pharmacopeial expectations such as USP . The episode also covers make vs buy testing decisions, when to outsource specialized testing such as CCIT and extractables and leachables, and how sponsors manage oversight of contract testing laboratories.Timestamps00:00 Welcome and Guest Introduction00:53 ICH Q2 vs MSA Mindset Shift04:37 Surrogate Standards for Mechanical Testing11:12 Platform Methods and ISO 1104015:14 ISO vs USP Verification Debate20:06 Outsourcing Analytical Testing Strategy24:07 Choosing the Right Test Lab26:20 Sponsor Oversight of Contract Labs30:09 Wrap UpAbout Jen RiterJen Riter is an analytical testing and laboratory leader with nearly three decades of experience working in pharmaceutical packaging, drug delivery systems, and combination products. She has held leadership roles at West Pharmaceutical Services and Kindeva Drug Delivery, where her work has focused on analytical method development, validation, and testing strategies for drug delivery systems and injectable combination products. She is also a contributor to the Combination Products Handbook, where she authored a chapter on analytical testing and method validation for combination products.About Subhi SaadehSubhi Saadeh is the Founder and Principal of Let's Combinate BioWorks, where he helps companies close the gaps between drug and device development, quality systems, and regulatory expectations. He is a Certified Quality Auditor and ISO 13485 Lead Auditor with leadership experience at Baxter, Pfizer, and Gilead Sciences including responsibility for management and oversight of assemble label pack sites and working with device primary, secondary and tertiary packaging suppliers. Subhi previously chaired the Combination Product Working Group for Rx-360, served as International Committee Chair for the Combination Products Coalition, and served on AAMI's Combination Products Committee. He also hosts the Let's Combinate podcast and is a writer and speaker on quality at the intersection of drugs and devices.
Eric the Analytical Iowan is back on the program. So much to breakdown and he's the guy to do it. Let's get into it.
Eric the Analytical Iowan is back on the program. So much to breakdown and he's the guy to do it. Let's get into it.
Eric the Analytical Iowan checks in on the program. We talk Hilary Clinton, the State of the Union and all the rest. Let's get into it.
Eric the Analytical Iowan checks in on the program. We talk Hilary Clinton, the State of the Union and all the rest. Let's get into it.
Are you always searching for the "why" behind the "what"?
It’s actually a good thing that some books push you to the edge of your ability to understand. But there’s no doubting the fact that dense, abstract and jargon-filled works can push you so far into the fog of frustration that you cannot blame yourself for giving up. But here’s the truth: You don’t have to walk away frustrated and confused. I’m going to share with you a number of practical strategies that will help you fill in the gaps of your reading process. Because that’s usually the real problem: It’s not your intelligence. Nor is it that the world is filled with books “above your level.” I ultimately don’t believe in “levels” as such. But as someone who taught reading courses at Rutgers and Saarland University, I know from experience that many learners need to pick up a few simple steps that will strengthen how they approach reading difficult books. And in this guide, you’ll learn how to read challenging books and remember what they say. I’m going to go beyond generic advice too. That way, you can readily diagnose: Why certain books feel so hard Use pre-reading tactics that prime your brain to deal with difficulties effectively Apply active reading techniques to lock in understanding faster Leverage accelerated learning tools that are quick to learn Use Artificial Intelligence to help convert tough convent into lasting knowledge without worrying about getting duped by AI hallucinations Whether you’re tacking philosophy, science, dense fiction or anything based primarily in words, the reading system you’ll learn today will help you turn confusion into clarity. By the end, even the most intimidating texts will surrender their treasures to your mind. Ready? Let’s break it all down together. https://www.youtube.com/watch?v=y9HLbY4jsFg Why Some Books Feel “Too Hard” (And What That Really Means) You know exactly how it feels and so do I. You sit down with a book that people claim is a classic or super-important. But within a few pages, your brain fogs over and you’re completely lost. More often than not, through glazed eyes, you start to wonder… did this author go out of his or her way to make this difficult? Are they trying to show off with all these literary pyrotechnics? Or is there a deliberate conspiracy to confuse readers like me? Rest assured. These questions are normal and well worth asking. The difficulty you might feel is never arbitrary in my experience. But there’s also no “single origin” explanation for why some books feel easier than others. It’s almost always a combination of factors, from cognitive readiness, lived experience, emotions and your physical condition throughout the day. This means that understanding why individual texts resist your understanding needs to be conducted on a case-by-case basis so you can move towards mastering anything you want to read. Cognitive Load: The Brain’s Processing “Stop Sign” “Cognitive load” probably needs no definition. The words are quite intuitive. You start reading something and it feels like someone is piling heavy bricks directly on top of your brain, squishing everything inside. More specifically, these researchers explain that what’s getting squished is specifically your working memory, which is sometimes called short-term memory. In practical terms, this means that when a book suddenly throws a bunch of unfamiliar terms at you, your working memory has to suddenly deal with abstract concepts, completely new words or non-linear forms of logic. All of this increases your cognitive load, but it’s important to note that there’s no conspiracy. In Just Being Difficult: Academic Writing in the Public Arena, a variety of contributors admit that they often write for other specialists. Although it would be nice to always compose books and articles for general readers, it’s not laziness. They’re following the codes of their discipline, which involves shorthand to save everyone time. Yes, it can also signal group membership and feel like an intellectual wall if you’re new to this style, but it’s simply a “stop sign” for your brain. And wherever there are stop signs, there are also alternative routes. Planning Your Detour “Roadmap” Into Difficult Books Let me share a personal example by way of sharing a powerful technique for making hard books easier to read. A few years ago I decided I was finally going to read Kant. I had the gist of certain aspects of his philosophy, but a few pages in, I encountered so many unfamiliar terms, I knew I had to obey the Cognitive Load Stop Sign and take a step back. To build a roadmap into Kant, I searched Google in a particular way. Rather than a search term like, “Intro to Kant,” I entered this tightened command instead: Filetype:PDF syllabus Kant These days, you can ask an LLM in more open language to simply give you links to the syllabi of the most authoritative professors who teach Kant. I’d still suggest that you cross-reference what you get on Google, however. If you’re hesitant about using either Google or AI, it’s also a great idea to visit a librarian in person to help you. Or, you can read my post about using AI for learning with harming your memory to see if it’s time to update your approach. Narrowing Down Your Options One way or another, the reason to consult the world’s leading professors is that their syllabi will provide you with: Foundational texts Core secondary literature Commentaries from qualified sources Essential historical references Once you’ve looked over a few syllabi, look through the table of contents of a few books on Amazon or Google Books. Then choose: 1-2 foundational texts to read before the challenging target book you want to master 1-2 articles or companion texts to read alongside In this way, you’ve turned difficulty into a path, not an obstacle. Pre-Reading Strategies That Warm Up Your Reading Muscles A lot of the time, the difficulty people feel when reading has nothing to do with the book. It’s just that you’re diving into unfamiliar territory without testing the waters first. Here are some simple ways to make unfamiliar books much easier to get into. Prime Like a Pro To make books easier to read, you can perform what is often called “priming” in the accelerated learning community. It is also sometimes called “pre-reading” and as this research article discusses, its success has been well-demonstrated. The way I typically perform priming is simple. Although some books require a slight change to the pattern, I typically approach each new book by reading: The back cover The index The colophon page The conclusion or afterword The most interesting or relevant chapter The introduction The rest of the book Activate Prior Knowledge Sometimes I will use a skimming and scanning strategy after reading the index to quickly familiarize myself with how an author approaches a topic with which I’m already familiar. This can help raise interest, excitement and tap into the power of context-dependent memory. For example, I recently started reading Doubt: A History by Jennifer Michael Hecht. Since the Renaissance memory master Giordano Bruno comes up multiple times, I was able to draw up a kind of context map of the books themes by quickly going through those passages. Take a Picture Walk Barbara Oakley and Terence Sejnjowski share a fantastic strategy in Learning How to Learn. Before reading, simply go through a book and look at all the illustrations, tables, charts and diagrams. It seems like a small thing. But it gives your brain a “heads up” about upcoming visual information that you may need to process than prose. I used to find visual information like this difficult, but after I started taking picture walks, I’m now excited to read “towards” these elements. If still find them challenging to understand, I apply a tip I learned from Tony Buzan that you might like to try: Rather than struggle to interpret a chart or illustration, reproduce it in your own hand. Here’s an example of how I did this when studying spaced repetition: As a result, I learned the graph and its concepts quickly and have never forgotten it. Build a Pre-Reading Ritual That Fits You There’s no one-sized-fits-all strategy, so you need to experiment with various options. The key is to reduce cognitive load by giving your mind all kinds of ways of understanding what a book contains. If it helps, you can create yourself a checklist that you slip into the challenging books on your list. That way, you’ll have both a bookmark and a protocol as you develop your own pre-reading style. Active Reading Techniques That Boost Comprehension Active reading involves deliberately applying mental activities while reading. These can include writing in the margins of your books, questioning, preparing summaries and even taking well-time breaks between books. Here’s a list of my favorite active reading strategies with ideas on how you can implement them. Using Mnemonics While Reading On the whole, I take notes while reading and then apply a variety of memory techniques after. But to stretch my skills, especially when reading harder books, I start the encoding process earlier. Instead of just taking notes, I’ll start applying mnemonic images. I start early because difficult terms often require a bit more spaced repetition. To do this yourself, the key is to equip yourself with a variety of mnemonic methods, especially: The Memory Palace technique The Pegword Method The Major System The PAO System And in some cases, you may want to develop a symbol system, such as if you’re studying physics or programming. Once you have these mnemonic systems developed, you can apply them in real time. For example, if you come across names and dates, committing them to memory as you read can help you keep track of a book’s historical arc. This approach can be especially helpful when reading difficult books because authors often dump a lot of names and dates. By memorizing them as you go, you reduce the mental load of having to track it all. For even more strategies you can apply while reading, check out my complete Mnemonics Dictionary. Strategic Questioning Whether you take notes or memorize in real-time, asking questions as you go makes a huge difference. Even if you don’t come up with answers, continually interrogating the book will open up your brain. The main kinds of questions are: Evaluative questions (checking that the author uses valid reasoning and address counterarguments) Analytical questions (assessing exactly how the arguments unfold and questioning basic assumptions) Synthetic questions (accessing your previous knowledge and looking for connections with other books and concepts) Intention questions (interrogating the author’s agenda and revealing any manipulative rhetoric) One medieval tool for questioning you can adopt is the memory wheel. Although it’s definitely old-fashioned, you’ll find that it helps you rotate between multiple questions. Even if they are as simple as who, what, where, when, how and why questions, you’ll have a mental mnemonic device that helps ensure you don’t miss any of them. Re-reading Strategies Although these researchers seem to think that re-reading is not an effective strategy, I could not live without it. There are three key kinds of re-reading I recommend. Verbalize Complexity to Tame It The first is to simply go back and read something difficult to understand out loud. You’d be surprised how often it’s not your fault. The author has just worded something in a clunky manner and speaking the phrasing clarifies everything. Verbatim Memorization for Comprehension The second strategy is to memorize the sentence or even an entire passage verbatim. That might seem like a lot of work, but this tutorial on memorizing entire passages will make it easy for you. Even if verbatim memorization takes more work, it allows you to analyze the meaning within your mind. You’re no longer puzzling over it on paper, continuing to stretch your working memory. No, you’ve effectively expanded at least a part of your working memory by bypassing it altogether. You’ve ushered the information into long-term memory. I’m not too shy to admit that I have to do this sometimes to understand everything from the philosophy in Sanskrit phrases to relatively simple passages from Shakespeare. As I shared in my recent discussion of actor Anthony Hopkins’ memory, I couldn’t work out what “them” referred to in a particular Shakespeare play. But after analyzing the passage in memory, it was suddenly quite obvious. Rhythmical Re-reading The third re-reading strategy is something I shared years ago in my post detailing 11 reasons you should re-read at least one book per month. I find this approach incredibly helpful because no matter how good you get at reading and memory methods, even simple books can be vast ecosystems. By revisiting difficult books at regular intervals, you not only get more out of them. You experience them from different perspectives and with the benefit of new contexts you’ve built in your life over time. In other words, treat your reading as an infinite game and never assume that you’ve comprehended everything. There’s always more to be gleaned. Other Benefits of Re-reading You’ll also improve your pattern recognition by re-treading old territory, leading to more rapid recognition of those patterns in new books. Seeing the structures, tropes and other tactics in difficult books opens them up. But without regularly re-reading books, it can be difficult to perceive what these forms are and how authors use them. To give you a simple example of a structure that appears in both fiction and non-fiction, consider in media res, or starting in the middle. When you spot an author using this strategy, it can immediately help you read more patiently. And it places the text in the larger tradition of other authors who use that particular technique. For even more ideas that will keep your mind engaged while tackling tough books, feel free to go through my fuller article on 7 Active Reading Strategies. Category Coloring & Developing Your Own Naming System For Complex Material I don’t know about you, but I do not like opening a book only to find it covered in highlighter marks. I also don’t like highlighting books myself. However, after practicing mind mapping for a few years, I realized that there is a way to combine some of its coloring principles with the general study principles of using Zettelkasten and flashcards. Rather than passively highlighting passages that seem interesting at random, here’s an alternative approach you can take to your next tour through a complicated book. Category Coloring It’s often helpful to read with a goal. For myself, I decided to tackle a hard book called Gödel Escher Bach through the lens of seven categories. I gave each a color: Red = Concept Green = Process Orange = Fact Blue = Historical Context Yellow = Person Purple = School of Thought or Ideology Brown = Specialized Terminology Example Master Card to the Categorial Color Coding Method To emulate this method, create a “key card” or “master card” with your categories on it alongside the chosen color. Use this as a bookmark as you read. Then, before writing down any information from the book, think about the category to which it belongs. Make your card and then apply the relevant color. Obviously, you should come up with your own categories and preferred colors. The point is that you bring the definitions and then apply them consistently as you read and extract notes. This will help bring structure to your mind because you’re creating your own nomenclature or taxonomy of information. You are also using chunking, a specific mnemonic strategy I’ve written about at length in this post on chunking as a memory tool. Once you’re finished a book, you can extract all the concepts and memorize them independently if you like. And if you emulate the strategy seen on the pictured example above, I’ve included the page number on each card. That way, I can place the cards back in the order of the book. Using this approach across multiple books, you will soon spot cross-textual patterns with greater ease. The catch is that you cannot allow this technique to become activity for activity’s sake. You also don’t want to wind up creating a bunch of informational “noise.” Before capturing any individual idea on a card and assigning it to a category, ask yourself: Why is this information helpful, useful or critical to my goal? Will I really use it again? Where does it belong within the categories? If you cannot answers these questions, either move on to the next point. Or reframe the point with some reflective thinking so that you can contextualize it. This warning aside, it’s important not to let perfectionism creep into your life. Knowing what information matters does take some practice. To speed up your skills with identifying critical information, please read my full guide on how to find the main points in books and articles. Although AI can certainly help these days, you’ll still need to do some work on your own. Do Not Let New Vocabulary & Terminology Go Without Memorization One of the biggest mistakes I used to make, even as a fan of memory techniques, slowed me down much more than necessary. I would come across a new term, look it up, and assume I’d remember it. Of course, the next time I came across it, the meaning was still a mystery. But when I got more deliberate, I not only remembered more words, but the knowledge surrounding the unfamiliar terms also stuck with greater specificity. For example, in reading The Wandering Mind by Jamie Kreiner, memorizing the ancient Greek word for will or volition (Prohairesis) pulled many more details about why she was mentioning it. Lo and behold, I started seeing the word in more places and connecting it to other ancient Greek terms. Memorizing those as well started to create a “moat of meaning,” further protecting a wide range of information I’d been battling. Understanding Why Vocabulary Blocks Comprehension The reason why memorizing words as you read is so helpful is that it helps clear out the cognitive load created by pausing frequently to look up words. Even if you don’t stop to learn a new definition, part of your working memory gets consumed by the lack of familiarity. I don’t always stop to learn new definitions while reading, but using the color category index card method you just discovered, it’s easy to organize unfamiliar words while reading. That way they can be tidily memorized later. I have a full tutorial for you on how to memorize vocabulary, but here’s a quick primer. Step One: Use a System for Capturing New Words & Terms Whether you use category coloring, read words into a recording app or email yourself a reminder, the key is to capture as you go. Once your reading session is done, you can now go back to the vocabulary list and start learning it. Step Two: Memorize the Terms I personally prefer the Memory Palace technique. It’s great for memorizing words and definitions. You can use the Pillar Technique with the word at the top and the definition beneath it. Or you can use the corners for the words and the walls for the definitions. Another idea is to photograph the cards you create and important them into a spaced repetition software like Anki. As you’ll discover in my complete guide to Anki, there are several ways you can combine Anki with a variety of memory techniques. Step Three: Use the Terms If you happened to catch an episode of the Magnetic Memory Method Podcast back when I first learned Prohairesis I mentioned it often. This simple habit helps establish long-term recall, reflection and establishes the ground for future recognition and use. Expand Understanding Using Video & Audio Media When I was in university, I often had to ride my bike across Toronto to borrow recorded lectures on cassette. Given the overwhelming tsunamis of complex ideas, jargon and theoretical frameworks I was facing, it was worth it. Especially since I was also dealing with the personal problems I shared with you in The Victorious Mind. Make no mistake: I do not believe there is any replacement for reading the core books, no matter how difficult they might be. But there’s no reason not to leverage the same ideas in multiple formats to help boost your comprehension and long-term retention. Multimedia approaches are not just about knowledge acquisition either. There have been many debates in the magical arts community that card magicians should read and not rely on video. But evidence-based studies like this one show that video instruction combined with reading written instructions is very helpful. The Science Behind Multi-Modal Learning I didn’t know when I was in university, or when I was first starting out with memdeck card magic that dual coding theory existed. This model was proposed by Allan Paivio, who noticed that information is processed both verbally and non-verbally. Since then, many teachers have focused heavily on how to encourage students to find the right combination of reading, visual and auditory instructional material. Here are some ideas that will help you untangle the complexity in your reading. How to Integrate Multimedia Without Overload Forgive me if this is a bit repetitive, but to develop flow with multiple media, you need to prime the brain. As someone who has created multiple YouTube videos, I have been stubborn about almost always including introductions. Why? Go Through the Intros Like a Hawk Because without including a broad overview of the topic, many learners will miss too many details. And I see this in the comments because people ask questions that are answered throughout the content and flagged in the introductions. So the first step is to be patient and go through the introductory material. And cultivate an understanding that it’s not really the material that is boring. It’s the contemporary issues with dopamine spiking that make you feel impatient. The good news is that you can possibly reset your dopamine levels so you’re better able to sit through these “priming” materials. One hack I use is to sit far away from my mouse and keep my notebook in hand. If I catch myself getting antsy, I perform a breathing exercise to restore focus. Turn on Subtitles When you’re watching videos, you can help increase your engagement by turning on the subtitles. This is especially useful in jargon-heavy video lessons. You can pause and still see the information on the screen for easier capture when taking notes. When taking notes, I recommend jotting down the timestamp. This is useful for review, but also for attributing citations later if you have to hand in an assignment. Mentally Reconstruct After watching a video or listening to a podcast on the topic you’re mastering, take a moment to review the key points. Try to go through them in the order they were presented. This helps your brain practice mental organization by building a temporal scaffold. If you’ve taken notes and written down the timestamps, you can easily check your accuracy. Track Your Progress For Growth & Performance One reason some people never feel like they’re getting anywhere is that they have failed to establish any points of reference. Personally, this is easy for me to do. I can look back to my history of writing books and articles or producing videos and be reminded of how far I’ve come at a glance. Not only as a writer, but also as a reader. For those who do not regularly produce content, you don’t have to start a blog or YouTube channel. Just keep a journal and create a few categories of what skills you want to track. These might include: Comprehension Retention Amount of books read Vocabulary growth Critical thinking outcomes Confidence in taking on harder books Increased tolerance with frustration when reading challenges arise You can use the same journal to track how much time you’ve spent reading and capturing quick summaries. Personally, I wish I’d started writing summaries sooner. I really only got started during grad school when during a directed reading course, a professor required that I had in a summary for every book and article I read. I never stopped doing this and just a few simple paragraph summaries has done wonders over the years for my understanding and retention. Tips for Overcoming Frustration While Reading Difficult Books Ever since the idea of “desirable difficulty” emerged, people have sought ways to help learners overcome emotional responses like frustration, anxiety and even shame while tackling tough topics. As this study shows, researchers and teachers have found the challenge difficult despite the abundance of evidence showing that being challenged is a good thing. Here are some strategies you can try if you continue to struggle. Embrace Cognitive Discomfort As we’ve discussed, that crushing feeling in your brain exists for a reason. Personally, I don’t think it ever goes away. I still regularly pick up books that spike it. The difference is that I don’t start up a useless mantra like, “I’m not smart enough for this.” Instead, I recommend you reframe the experience and use the growth mindset studied by Carol Dweck, amongst others. You can state something more positive like, “This book is a bit above my level, but I can use tactics and techniques to master it.” I did that very recently with my reading of The Xenotext, parts of which I still don’t fully understand. It was very rewarding. Use Interleaving to Build Confidence I rotate through draining books all the time using a proven technique called interleaving. Lots of people are surprised when I tell them that I rarely read complex and challenging books for longer than fifteen minutes at a time. But I do it because interleaving works. Which kinds of books can you interleave? You have choices. You can either switch in something completely different, or switch to a commentary. For example, while recently reading some heavy mathematical theories about whether or not “nothing” can exist, I switched to a novel. But back in university, I would often stick within the category while at the library. I’d read a core text by a difficult philosopher, then pick up a Cambridge Companion and read an essay related to the topic. You can also interleave using multimedia sources like videos and podcasts. Interleaving also provides time for doing some journaling, either about the topic at hand or some other aspect of your progress goals. Keep the Big Picture in Mind Because frustration is cognitively training, it’s easy to let it drown out your goals. That’s why I often keep a mind map or some other reminder on my desk, like a couple of memento mori. It’s also possible to just remember previous mind maps you’ve made. This is something I’m doing often at the moment as I read all kinds of boring information about managing a bookshop for my Memory Palace bookshop project first introduced in this video: https://www.youtube.com/watch?v=utcJfeQZC2c It’s so easy to get discouraged by so many rules and processes involved in ordering and selling books, that I regularly think back to creating this mind map with Tony Buzan years ago. In case my simple drawings on this mind map for business development doesn’t immediately leap out at you with its meanings, the images at the one o’clock-three o’clock areas refer to developing a physical Memory Palace packed with books on memory and learning. Developing and keeping a north star in mind will help you transform the process of reading difficult books into a purposeful adventure of personal development. Even if you have to go through countless books that aren’t thrilling, you’ll still be moving forward. Just think of how much Elon Musk has read that probably wasn’t all that entertaining. Yet, it was still essential to becoming a polymath. Practice Seeing Through The Intellectual Games As you read harder and harder books, you’ll eventually come to realize that the “fluency” some people have is often illusory. For example, some writers and speakers display a truly impressive ability to string together complex terminology, abstract references and fashionable ideas of the day in ways that sound profound. Daniel Dennett frequently used a great term for a lot of this verbal jujitsu that sounds profound but is actually trivial. He called such flourishes “deepities.” https://www.youtube.com/watch?v=ey-UeaSi1rI This kind of empty linguistic dexterity will be easier for you to spot when you read carefully, paraphrase complex ideas in your own words and practice memorizing vocabulary frequently. When you retain multiple concepts and practice active questioning in a large context of grounded examples and case studies, vague claims will not survive for long in your world. This is why memory training is about so much more than learning. Memorization can equip you to think independently and bring clarity to fields that are often filled with gems, despite the fog created by intellectual pretenders more interested in word-jazz than actual truth. Using AI to Help You Take On Difficult Books As a matter of course, I recommend you use AI tools like ChatGPT after doing as much reading on your own as possible. But there’s no mistaking that intentional use of such tools can help you develop greater understanding. The key is to avoid using AI as an answer machine or what Nick Bostrom calls an “oracle” in his seminal book, Superintelligence. Rather, take a cue from Andrew Mayne, a science communicator and central figure at OpenAI and host of their podcast. His approach centers on testing in ways that lead to clarity of understanding and retention as he uses various mnemonic strategies. https://www.youtube.com/watch?v=JlzD_6Olaqw Beyond his suggestions, here are some of my favorite strategies. Ask AI to Help Identify All Possible Categories Connected to a Topic A key reason many people struggle to connect ideas is simply that they haven’t developed a mental ecosystem of categories. I used to work in libraries, so started thinking categorically when I was still a teenager. But these days, I would combine how traditional libraries are structured with a simple prompt like: List all the possible categories my topic fits into or bridges across disciplines, historical frameworks and methodologies. Provide the list without interpretation or explanation so I can reflect. A prompt like this engineers a response that focuses on relationships and lets your brain perform the synthetic thinking. Essentially, you’ll be performing what some scientists call schema activation, leading to better personal development outcomes. Generate Lists of Questions To Model Exceptional Thinkers Because understanding relies on inquiry, it’s important to practice asking the best possible questions. AI chat bots can be uniquely useful in this process provided that you explicitly insist that it helps supply you excellent questions without any answers. You can try a prompt like: Generate a list of questions that the world’s most careful thinkers in this field would ask about this topic. Do not provide any answers. Just the list of questions. Do this after you’ve read the text and go through your notes with fresh eyes. Evaluate the material with questions in hand, ideally by writing out your answers by hand. If you need your answers imported into your computer, apps can now scan your handwriting and give you text file. Another tip: Don’t be satisfied with the first list of questions you get. Ask the AI to dig deeper. You can also ask the AI to map the questions into the categories you previously got help identifying. For a list of questions you can put into your preferred chat bot, feel free to go through my pre-AI era list of philosophical questions. They are already separated by category. Use AI to Provide a Progress Journal Template If you’re new to journaling, it can be difficult to use the technique to help you articulate what you’re reading and why the ideas are valuable. And that’s not to mention working out various metrics to measure your growth over time. Try a prompt like this: Help me design a progress journal for my quest to better understand and remember difficult books. Include sections for me to list my specific goals, vocabulary targets, summaries and various milestones I identify. Make it visual so I can either copy it into my own print notebook or print out multiple copies for use over time. Once you have a template you’re happy to experiment with, keep it visible in your environment so you don’t forget to use it. Find Blind Spots In Your Summaries Many AIs have solid reasoning skills. As a result, you can enter your written summaries and have the AI identify gaps in your knowledge, blind spots and opportunities for further reading. Try a prompt like: Analyze this summary and identify any blind spots, ambiguities in my thinking or incompleteness in my understanding. Suggest supplementary reading to help me fill in any gaps. At the risk of repetition, the point is that you’re not asking for the summaries. You’re asking for assessments that help you diagnose the limits of your understanding. As scientists have shown, metacognition, or thinking about your thinking can help you see errors much faster. By adding an AI into the mix, you’re getting feedback quickly without having to wait for a teacher to read your essay. Of course, AI outputs can be throttled, so I find it useful to also include a phrase like, “do not throttle your answer,” before asking it to dig deeper and find more issues. Used wisely, you will soon see various schools of thought with much greater clarity, anticipate how authors make their moves and monitor your own blind spots as you read and reflect. Another way to think about the power of AI tools is this: They effectively mirror human reasoning at a species wide level. You can use them to help you mirror more reasoning power by regularly accessing and practicing error detection and filling in the gaps in your thinking style. Why You Must Stop Abandoning Difficult Books (At Least Most of the Time) Like many people, I’m a fan of Scott Young’s books like Ultralearning and Get Better at Anything. He’s a disciplined thinker and his writing helps people push past shallow learning in favor of true and lasting depth. However, he often repeats the advice that you should stop reading boring books. In full transparency, I sometimes do this myself. And Young adds a lot of context to make his suggestion. But I limit abandoning books as much as possible because I don’t personally find Young’s argument that enjoyment and productivity go together. On the contrary, most goals that I’ve pursued have required fairly intense periods of delaying gratification. And because things worth accomplishing generally do require sacrifice and a commitment to difficulty, I recommend you avoid the habit of giving up on books just because they’re “boring” or not immediately enjoyable. I’ll bet you’ll enjoy the accomplishment of understanding hard books and conquering their complexity far more in the end. And you’ll benefit more too. Here’s why I think so. The Hidden Cost of Abandoning Books You’ve Started Yes, I agree that life is short and time is fleeting. But if you get into the habit of abandoning books at the first sign of boredom, it can quickly become your default habit due to how procedural memory works. In other words, you’re given your neurons the message that it’s okay to escape from discomfort. That is a very dangerous loop to throw yourself into, especially if you’re working towards becoming autodidactic. What you really need is to develop the ability to stick with complexity, hold ambiguous and contradictory issues in your mind and fight through topic exhaustion. Giving up on books on a routine basis? That’s the opposite of developing expertise and resilience. The AI Risk & Where Meaning is Actually Found We just went through the benefits of AI, so you shouldn’t have issues. But I regularly hear from people and have even been on interviews where people use AI to summarize books I’ve recomended. This is dangerous because the current models flatten nuance due to how they summarize books based on a kind of “averaging” of what its words predictability mean. Although they might give you a reasonable scaffold of a book’s structure, you won’t get the friction created by how authors take you through their thought processes. In other words, you’ll be using AI models that are not themselves modeling the thinking that reading provides when you grind your way through complex books. The Treasure of Meaning is Outside Your Comfort Zone Another reason to train for endurance is that understanding doesn’t necessarily arrive while reading a book or even a few weeks after finishing it. Sometimes the unifying insights land years later. But if you don’t read through books that seem to be filled with scattered ideas, you cannot gain any benefit from them. Their diverse points won’t consolidate in your memory and certainly won’t connect with other ideas later. So I suggest you train your brain to persist as much as possible. By drawing up the support of the techniques we discussed today and a variety of mnemonic support systems, you will develop persistence and mine more gold from everything you read. And being someone who successfully mines for gold and can produce it at will is the mark of the successful reading. Not just someone who consumes information efficiently, but who can repeatedly connect and transform knowledge year after year due to regularly accumulating gems buried in the densest and most difficult books others cannot or will not read. Use Struggle to Stimulate Growth & You Cannot Fail As you’ve seen, challenging books never mean that you’re not smart enough. It’s just a matter of working on your process so that you can tackle new forms of knowledge. And any discomfort you feel is a signal that a great opportunity and personal growth adventure awaits. By learning how to manage cognitive load, fill in the gaps in your background knowledge and persist through frustration, you can quickly become the kind of reader who seeks out complexity instead of flinching every time you see it. Confusion has now become a stage along the path to comprehension. And if you’re serious about mastering increasingly difficult material, understanding and retaining it, then it’s time to upgrade your mental toolbox. Start now by grabbing my Free Memory Improvement Course: Inside, you’ll discover: The Magnetic Memory Method for creating powerful Memory Palaces How to develop your own mnemonic systems for encoding while reading Proven techniques that deepen comprehension, no matter how abstract or complex your reading list is And please, always remember: The harder the book, the greater rewards. And the good news is, you’re now more than ready to claim them all.
Eric (The Analytical Iowan) is back on the program. And none too soon. There's so much going on and we need his insights. Let's get into it.
Eric (The Analytical Iowan) is back on the program. And none too soon. There's so much going on and we need his insights. Let's get into it.
Honson Lau is a respected part-time fishing guide based in South Florida, balancing his time on the water with a professional career in IT at Baptist Health South Florida. Every opportunity outside of work is devoted to the flats, where Honson has built a reputation as a technical, and highly skilled guide. While well-versed in targeting all flats species, Honson's true specialty is hunting big, intelligent bonefish on fly. His success is reflected in competition results—together with angler Jeremy Alderman, Honson has captured two Spring Fly Bonefish Tournament wins and two Fall Fly Bonefish Tournament wins, firmly establishing their team among the very best in competitive bonefishing. Honson began fishing the waters of Miami, Biscayne Bay, and Everglades National Park in the 1990s, where he was mentored and influenced by accomplished anglers & guides Frank Perez and Tim Mahaffey. Those early years laid the foundation for a lifetime of learning, observation, and respect for South Florida's complex fisheries. He officially began his guiding career in 2009, and since then has continuously refined his skills to become a top guide for all species on the flats, including bonefish, permit, tarpon, snook, and redfish. Beyond guiding, Honson is an accomplished fly tyer, photographer, hunter, and cook, pursuits that reflect his deep appreciation for the outdoors and the full experience of life on the water. Analytical by nature and passionate by choice, Honson brings a unique blend of technical expertise, competitive experience, and genuine enthusiasm to every day on the flats.
1/4. Market Adaptations, Fossil Fuels, and Physical Limits of Renewables — Terry Anderson (Editor) — Andersonintroduces Adapt and Be Adept, examining market-driven responses to climate change while applying Pascal's Wageranalytical framework. The book emphasizes the necessity of localized control in climate adaptation strategies, exemplified by Alaskan Native Villages implementing place-based solutions. Anderson details Mark Mills' argument that hydrocarbons remain essential to industrial civilization due to the extreme economic costs and insurmountable physical limitations of renewable energy sources, particularly regarding solar and wind power generation, compounded by critical battery storage capacity constraints. 1968