Podcasts about dengue virus

Understanding Dengue, including virology and Dengue pathophysiology. We also look at the 3 clinical stages of Dengue and how that corresponds with Dengue Haemorrhagic Fever and Dengue Shock Syndrome, as well as diagnosis and Dengue treatment options. Cconsider subscribing on YouTube (if you found any of the info useful!): https://www.youtube.com/channel/UCRks8wB6vgz0E7buP0L_5RQ?sub_confirmation=1Patreon: https://www.patreon.com/rhesusmedicineBuy Us A Coffee!: https://www.buymeacoffee.com/rhesusmedicineTimestamps:0:00 What is Dengue Virus? 0:23 Dengue Virology1:08 Dengue Epidemiology 1:35 Dengue Pathophysiology2:27 Dengue Symptoms4:10 Dengue WHO Classification (Dengue Haemorrhagic Fever / Dengue Shock Syndrome) 5:02 Dengue Diagnosis7:29 Dengue TreatmentReferencesBMJ Best Practice (2025) - “Dengue fever”. Available at https://bestpractice.bmj.com/topics/en-gb/1197/Omar Saeed, Ahmer Asif, Chapter 2 - Dengue virus disease; the origins, Editor(s): Adnan I. Qureshi, Omar Saeed, Dengue Virus Disease, Academic Press, 2020, Pages 9-16, ISBN 9780128182703, https://doi.org/10.1016/B978-0-12-818270-3.00002-3. (https://www.sciencedirect.com/science/article/pii/B9780128182703000023)Please remember this podcast and all content from Rhesus Medicine is meant for educational purposes only and should not be used as a guide to diagnose or to treat. Please consult a healthcare professional for medical advice. #medicalmnemonic #medicalmnemonics #rhesusmedicine #studymedicine #studygram #medstudent #medicalschool

 Spring and summer usher in mosquito season, bringing an increased risk of mosquito-borne diseases. Recently, the CDC Health Alert Network (HAN) issued a warning about Dengue virus in the U.S. The Divas delve into its transmission, symptoms, and ways to prevent exposure. Resources:CDC Health Alert Network (HAN) Ongoing Risk of Dengue Virus Infections  https://www.cdc.gov/han/2025/han00523.htmlCDC - About Dengue  https://www.cdc.gov/dengue/CDC - Travelers' Health  https://wwwnc.cdc.gov/travelAmerican Medical Association (AMA) How to Stay Healthy when Traveling   https://bit.ly/43VwNhi https://www.thecompliancedivas.com

Can you stay healthy when traveling? How many measles outbreaks in 2025? Which countries have measles? What is immune amnesia? What is sleep maxxing? Discussing rising measles cases globally, avian flu in chickens, dengue fever news, immune amnesia, and how to get better sleep with the latest sleep trend in 2025 with AMA's Vice President of Science, Medicine and Public Health, Andrea Garcia, JD, MPH. American Medical Association CXO Todd Unger hosts.

Boueke, Andreas www.deutschlandfunk.de, Tag für Tag

Moin, ich komme gerade aus Frankreich, wo ich extrem von der Tigermücke geplagt wurde. Deshalb bin ich aufgeschreckt, als ich hörte, dass sich die Tigermücke jetzt auch in Norddeutschland ausbreitet. Meine Befürchtungen, die Tigermücke könnte in Hamburg demnächst auch das Dengue-Virus übertragen, hat mir aber Prof. Jonas Schmit-Chanasit vom Bernhard-Nocht-Institut für Tropenmedizin genommen. Viel Spaß beim Hören (und Beruhigtwerden) wünscht Maiken Was war heute in Hamburg los? Maiken Nielsen und Ole Wackermann werfen im wöchentlichen Wechsel zum Tagesende einen Blick auf die News und das aktuelle Stadtgeschehen. Das sind die Nachrichten heute mit Maiken Nielsen, am Montag, 29. Juli 2024: +++ Bahnverkehr in Hamburg ab heute wegen Baustellen eingeschränkt +++ Die Deutsche Bahn und Hamburger Hochbahn nutzen die Sommerferien in der Hansestadt, um Bauarbeiten an der S-Bahn und U-Bahn durchzuführen. Mehr dazu: https://www.ndr.de/sbahn1008.html +++ Dachbrand in Hummelsbüttel: Vier Leichtverletzte +++ Die Hamburger Feuerwehr ist am Montagvormittag zu einem Großeinsatz in den Stadtteil Hummelsbüttel gerufen worden. Dort brennt das Dach eines mehrstöckigen Wohnhauses. Es gibt Verletzte und eine starke Rauchentwicklung.

Infection control consultant Katherine West provides information about Dengue Virus, an ailment EMS providers may encounter this summer.

New York State Department of Health:https://www.health.ny.gov/diseases/communicable/dengue_fever/CDC:https://www.cdc.gov/dengue/Local Health Departmentshttps://www.health.ny.gov/contact/contact_information/

Asia is on the cusp of a summer of life-threatening dengue fever.  Synopsis: Every fourth Friday of the month, The Straits Times' global contributor Nirmal Ghosh shines a light on Asian perspectives of global and Asian issues with expert guests. Dengue fever case numbers have gone up across the global tropics. This includes Singapore, a model in many respects for health surveillance and epidemic control, and mosquito control. In the first quarter of 2024, Singapore recorded more than double the number of cases than in the same period in 2023.  Meanwhile across the world, Latin America and the Caribbean have been warned to prepare for their worst dengue season ever.  The long war against dengue must contend with many factors including climate, weather, and human behaviour. Even without an outbreak or epidemic, dengue may circulate silently among populations.  No single solution is perfect. Dengue vaccines have been developed, but there are four strains of the virus, and the vaccines have different degrees of efficacy.  The key to effective dengue control is health surveillance and a good laboratory system - and in Singapore's case especially, collaboration with neighbouring countries. Vaccinating populations could help complement other dengue and mosquito control measures. Globally, we discuss how countries must build urban infrastructure to be less mosquito-friendly.  Nirmal Ghosh hosts his guests who are also global dengue gurus: Dr. Duane Gubler, Emeritus Professor and founding director of the Emerging Infectious Diseases Signature Research Programme at Duke-NUS Medical School Dr. Ooi Eng Eong is a Professor in the Programme in Emerging Infectious Diseases at Duke-NUS Medical School Highlights (click/tap above):  2:31 Dengue vaccine - the solution for Singapore?  8:06 Important lessons from Sars and Covid-19 16:03 Why a single vaccination cannot prevent dengue entirely  17:52 Contrarian view: Global warming is not the main cause of dengue fever  20:00 Better living standards can help control mosquito-borne diseases 23:19 Should new cities consider mosquito-related issues in building plans? Produced by: Nirmal Ghosh (nirmal@sph.com.sg) and Fa'izah Sani Edited by: Fa'izah Sani Follow Asian Insider with Nirmal Ghosh every fourth Friday of the month here: Channel: https://str.sg/JWa7 Apple Podcasts: https://str.sg/JWa8 Spotify: https://str.sg/JWaX Website: http://str.sg/stpodcasts Feedback to: podcast@sph.com.sg Follow Nirmal Ghosh on X: https://str.sg/JD7r Read Nirmal Ghosh's articles: https://str.sg/JbxG Register for Asian Insider newsletter: https://str.sg/stnewsletters --- Discover more ST podcast channels: All-in-one ST Podcasts channel: https://str.sg/wvz7  The Usual Place: https://str.sg/wEr7u  In Your Opinion: https://str.sg/w7Qt  COE Watch: https://str.sg/iTtE  Asian Insider: https://str.sg/JWa7  Health Check: https://str.sg/JWaN  Green Pulse: https://str.sg/JWaf  Your Money & Career: https://str.sg/wB2m  Hard Tackle: https://str.sg/JWRE  #PopVultures: https://str.sg/JWad  Music Lab: https://str.sg/w9TX  --- ST Podcast website: http://str.sg/stpodcasts  ST Podcasts YouTube: https://str.sg/4Vwsa  --- Special edition series: True Crimes Of Asia (6 eps): https://str.sg/i44T  The Unsolved Mysteries of South-east Asia (5 eps): https://str.sg/wuZ2  Invisible Asia (9 eps): https://str.sg/wuZn  Stop Scams (10 eps): https://str.sg/wuZB  Singapore's War On Covid (5 eps): https://str.sg/wuJa  --- Get The Straits Times' app, which has a dedicated podcast player section: The App Store: https://str.sg/icyB  Google Play: https://str.sg/icyX  #STAsianInsiderSee omnystudio.com/listener for privacy information.

Asia is on the cusp of a summer of life-threatening dengue fever.  Synopsis: Every fourth Friday of the month, The Straits Times' global contributor Nirmal Ghosh shines a light on Asian perspectives of global and Asian issues with expert guests. Dengue fever case numbers have gone up across the global tropics. This includes Singapore, a model in many respects for health surveillance and epidemic control, and mosquito control. In the first quarter of 2024, Singapore recorded more than double the number of cases than in the same period in 2023.  Meanwhile across the world, Latin America and the Caribbean have been warned to prepare for their worst dengue season ever.  The long war against dengue must contend with many factors including climate, weather, and human behaviour. Even without an outbreak or epidemic, dengue may circulate silently among populations.  No single solution is perfect. Dengue vaccines have been developed, but there are four strains of the virus, and the vaccines have different degrees of efficacy.  The key to effective dengue control is health surveillance and a good laboratory system - and in Singapore's case especially, collaboration with neighbouring countries. Vaccinating populations could help complement other dengue and mosquito control measures. Globally, we discuss how countries must build urban infrastructure to be less mosquito-friendly.  Nirmal Ghosh hosts his guests who are also global dengue gurus: Dr. Duane Gubler, Emeritus Professor and founding director of the Emerging Infectious Diseases Signature Research Programme at Duke-NUS Medical School Dr. Ooi Eng Eong is a Professor in the Programme in Emerging Infectious Diseases at Duke-NUS Medical School Highlights (click/tap above):  2:31 Dengue vaccine - the solution for Singapore?  8:06 Important lessons from Sars and Covid-19 16:03 Why a single vaccination cannot prevent dengue entirely  17:52 Contrarian view: Global warming is not the main cause of dengue fever  20:00 Better living standards can help control mosquito-borne diseases 23:19 Should new cities consider mosquito-related issues in building plans? Produced by: Nirmal Ghosh (nirmal@sph.com.sg) and Fa'izah Sani Edited by: Fa'izah Sani Follow Asian Insider with Nirmal Ghosh every fourth Friday of the month here: Channel: https://str.sg/JWa7 Apple Podcasts: https://str.sg/JWa8 Spotify: https://str.sg/JWaX Website: http://str.sg/stpodcasts Feedback to: podcast@sph.com.sg Follow Nirmal Ghosh on X: https://str.sg/JD7r Read Nirmal Ghosh's articles: https://str.sg/JbxG Register for Asian Insider newsletter: https://str.sg/stnewsletters --- Discover more ST podcast channels: All-in-one ST Podcasts channel: https://str.sg/wvz7  The Usual Place: https://str.sg/wEr7u  In Your Opinion: https://str.sg/w7Qt  COE Watch: https://str.sg/iTtE  Asian Insider: https://str.sg/JWa7  Health Check: https://str.sg/JWaN  Green Pulse: https://str.sg/JWaf  Your Money & Career: https://str.sg/wB2m  Hard Tackle: https://str.sg/JWRE  #PopVultures: https://str.sg/JWad  Music Lab: https://str.sg/w9TX  --- ST Podcast website: http://str.sg/stpodcasts  ST Podcasts YouTube: https://str.sg/4Vwsa  --- Special edition series: True Crimes Of Asia (6 eps): https://str.sg/i44T  The Unsolved Mysteries of South-east Asia (5 eps): https://str.sg/wuZ2  Invisible Asia (9 eps): https://str.sg/wuZn  Stop Scams (10 eps): https://str.sg/wuZB  Singapore's War On Covid (5 eps): https://str.sg/wuJa  --- Get The Straits Times' app, which has a dedicated podcast player section: The App Store: https://str.sg/icyB  Google Play: https://str.sg/icyX  #STAsianInsiderSee omnystudio.com/listener for privacy information.

Interview with research scientist Adam Waickman, PhD

Sam Cassidy is part owner and head striking coach at Southside MMA, Phuket – one of the best MMA gyms in Thailand. He was born and raised in Melbourne, Australia. From an early age, Sam showed signs of being a gifted athlete and later pursued a career in professional rugby and golf. A bad injury forced an early stop to his sporting life which eventually led him down a path of drinking and gambling. Luckily a helping hand was close by and Sam was convinced to travel to Thailand for a weight loss camp that led to a fight at the famous BBQ bash at Tiger Muay Thai. Since then he has been making waves across the Thai stadium circuits and even started a clothing brand, Muay Thai Life. The cards have been dealt and we have been rewarded with a royal flush – Sam Cassidy joins us today to talk about his life as a professional athlete and as head coach of Southside MMA. In this episode, we start off on a sick note to discuss a recent deadly illness Sam picked up during the Songkran water festival – Dengue Fever. We discuss his early life as a professional athlete, how partying and gambling changed his life, moving to Thailand and starting a new life in the ring. Join us for another episode of the Fruiting Body Podcast, we enter the ring and exchange some punches with Southside MMA's head striking coach, Sam Cass. Today we discuss the purse structure between professional fighters and their gyms, what it's like training with UFC athletes, how to take the right opportunities for success and of course get to know the ins and out of the now famous Southside MMA & fitness gym in Rawai, Phuket. #denguefever #thailand #podcast 

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.03.24.534108v1?rss=1 Authors: Hoffstadt, J. G., Wotring, J. W., Porter, S., Halligan, B. S., O'Meara, M. J., Tai, A. W., Sexton, J. Z. Abstract: Dengue Virus (DENV) causes dengue fever, a pandemic-potential disease with currently no FDA-approved antivirals. Additionally, the available vaccine for DENV can increase the risk of severe dengue fever for those who have never had a DENV infection due to antibody-dependent enhancements. Thus, there is an urgent need to identify dengue virus antivirals. Antivirals that target NS4B, the replication compartment forming protein of DENV and the flavivirus family, are a promising new drug class that minimize cytotoxic effects to host cells. Drug-repurposing and high-content screening were leveraged to efficiently identify antivirals likely to inhibit NS4B. Using high-content screening, we quantified the morphological patterns of NS4B and envelope (E) protein expression versus time and developed a viral pseudotime model that was able to predict the infection progression to enable drug screening. We then developed a single-cell infection classifier for antiviral efficacy and performed high-throughput drug screening of 960 compounds. We identified four concentration-dependent inhibitors of DENV with nanomolar potencies including: Nexium, Pralatrexate, GW4064, and LY411575. LY411575, a gamma secretase inhibitor, exhibited an IC50 of 72nM and reduced percent infection to levels indistinguishable from the mock infection control. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Interview with Upstate research scientist Adam Waickman, PhD

Wärmere Sommer begünstigen die Ausbreitung exotischer Stechmückenarten auch in Deutschland. Virologe Jonas Schmidt-Chanasit vom Bernhard-Nocht-Institut für Tropenmedizin fordert eine intensivere und professionelle Bekämpfung der Insekten. Er warnt vor Fällen des Dengue-Virus.

On this episode, Dixie and Stephanie talk with Dr. Miguel Pinedo from the College of Education. He focuses on studying the health implications of immigration policies on migrants residing on both sides of the US-Mexico border. Although a research-trained professor, in the classroom, Dr. Pinedo expounds on how he has developed practices to humanize his research to help students viscerally connect the data and findings to real life experiences. Thanks for joining us on The Other Side of Campus! ABOUT THE GUEST https://apps.jsg.utexas.edu/profiles/files/photos/miguel_pinedo_banuelos_3747_thumb.jpg Miguel Pinedo is an Assistant Professor in Department of Kinesiology and Health Education at The University of Texas at Austin. He has an invested interest in better understanding the intersection between migration and health. Though migrant health has become an important facet of health research, migration has rarely been examined as a social determinant of health. Pinedo's work addresses this critical area by focusing on how different migration experiences contribute to health disparities, particularly among Latino populations. Specifically, his work investigates how social- and structural-level factors associated with migration to the US; voluntary and forced migration (e.g., deportation); domestic migration within Mexico; and migration to high-risk environments (e.g., settings with increased availability of alcohol and drugs) relate to the epidemiology of substance abuse, HIV risk, and related harms. A large proportion of his work has focused on Mexican migrants residing on both sides of the US-Mexico border, a high-risk region for alcohol and drug abuse and HIV. Overall, his research underscores the importance of migration-related factors in shaping health behaviors, risk practices, and health outcomes. Prior to joining UT, Pinedo received his PhD in Global Health from the UC San Diego and completed his postdoctoral training at UC Berkeley. He also previously earned his Master in Public Health from UC Berkeley. PRODUCER'S NOTE: This episode was recorded on November 12th, 2021 via Zoom. CREDITS Assistant Producers/Hosts: Stephanie Seidel Holmsten, Dixie Stanforth (Intro theme features the following faculty in order: Jen Moon, Daron Shaw, Rich Reddick, Diane McDaniel Rhodes, Siobhan McCusker, Moriba Jah, and Stephanie Seidel Holmsten) Theme Music: Charlie Harper (www.charlieharpermusic.com) Additional Background music: Charlie Harper, Michelle Daniel Trio, Eaters, Edoy, Maarten Schelkens, Ketsa Producer: Michelle S. Daniel Executive Producer: Mary C. Neuburger Connect with us! Facebook: /texasptf Twitter: @TexasPTF Website: https://texasptf.org DISCLAIMER: The Other Side of Campus is a member of the Texas Podcast Network, brought to you by The University of Texas at Austin. Podcasts are produced by faculty members and staffers at UT Austin who work with University Communications to craft content that adheres to journalistic best practices. The University of Texas at Austin offers these podcasts at no charge. Podcasts appearing on the network and this webpage represent the views of the hosts, not of The University of Texas at Austin. https://files.fireside.fm/file/fireside-uploads/images/1/1ed1b736-a1fa-4ae4-b346-90d58dfbc8a4/4GSxOOOU.png Special Guest: Miguel Pinedo.

Ang kautusan ng Diyos ay hanggan dahil ang Pag-ibig nya sa atin ay walang hanggan din.

Ang kautusan ng Diyos ay hanggan dahil ang Pag-ibig nya sa atin ay walang hanggan din.

Today, in episode 321, our expert Infectious Disease and Community Medicine doctors discuss the latest on COVID-19. We talk about the increase in black fungus in India, as well as the decrease of dengue virus cases due to an experiment involving mosquitoes. As always, join us for all the COVID-19 information you need, explained in clear terms by health experts. --- Send in a voice message: https://anchor.fm/noisefilter/message

During this episode , Dr.Arianne Harvey provides a detailed look at Dengue Fever, an illness endemic to Barbados caused by Dengue Virus. She discusses from symptoms to serotypes, diagnosis to management and certainly a special piece on prevention. Follow us at https://www.facebook.com/cornerstonemedcc/ or instagram @cornerstonemed_246

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.11.11.378646v1?rss=1 Authors: Lee, W. H., Liu, W., Fan, J.-S., Yang, D. Abstract: The viral protease domain (NS3pro) of dengue virus is essential for virus replication and its cofactor NS2B is indispensable for the proteolytic function. Although several NS3pro-NS2B complex structures have been obtained, the dynamic property of the complex remains poorly understood. Using NMR relaxation techniques, here we found that NS3pro-NS2B exists in both closed and open conformations which are in dynamic equilibrium on a sub-millisecond timescale in aqueous solution. Our structural information indicates that the C-terminal region of NS2B is disordered in the open conformation but folded in the closed conformation. Using mutagenesis, we showed that the closed-open conformational equilibrium can be shifted by changing NS2B stability. Moreover, we revealed that the proteolytic activity of NS3pro-NS2B correlates well with the population of the closed conformation. Our results suggest that the closed-open conformational equilibrium can be used by both nature and man to control the replication of dengue virus. Copy rights belong to original authors. Visit the link for more info

Juliet is a PhD student in Pharmaceutical Sciences at the University of Maryland, Baltimore. She is originally from Nigeria, and is a Pharmacist by training. Her passion for research and development led her to move to the United States in 2017 to pursue a Masters in Pharmaceutical Sciences, and now a PhD. Her current research project focuses structural biology, specifically how the Dengue Virus can he targeted to come up with potential therapeutics or vaccines for Dengue fever.

Green Pulse Ep 20: Singapore's battle against dual invasion of coronavirus and dengue virus 11:56 mins Synopsis: Green Pulse is an environmental podcast series at The Straits Times which analyses the beat of the changing environment, from biodiversity conservation to climate change. Tune in to this episode to find out about Singapore's efforts to bring forward an increased fight against dengue in 2020, which has so far already recorded double the number of dengue infections compared to last year, in the midst of the developing Covid-19 crisis. Tackling the spread of the two different viruses requires two different approaches. But they both need individual citizens to play their part, whether in terms of stepping up personal hygiene to combat the spread of Covid-19, to reducing breeding grounds for the Aedes aegypti mosquito. These efforts would all help to ensure that Singapore does not have two crises to fight.  In the fourth of a series of podcast episodes based on The Straits Times' The Big Story video, ST's environment correspondent Audrey Tan chats with a panel of experts to discuss the importance of personal and public hygiene, as Singapore continues its battle against Covid-19. Subjects covered are the drive for cleanliness amid disease, the existing state of hygiene, the need for a greater appreciation of cleaners and life beyond Covid-19. The panel includes: 1. Mr Masagos Zulkifli, Minister for the Environment and Water Resources 2. Professor Wang Linfa, infectious diseases expert at Duke-NUS Medical School 3. Mr Edward D'Silva, chairman, Public Hygiene Council 4. Mr Tai Ji Choong, director of the Department Of Public Cleanliness, The National Environment Agency (NEA) Produced by: Audrey Tan (audreyt@sph.com.sg) & David Fogarty (dfogarty@sph.com.sg) & Ernest Luis Follow Audrey Tan on Twitter Follow David Fogarty on Twitter Edited by: Adam Azlee Discover more Green Pulse podcast episodes on: Channel: https://str.sg/JWaf Apple Podcasts: https://str.sg/JWaY Spotify: https://str.sg/JWag Google Podcasts: https://str.sg/JWaM Website: http://str.sg/stpodcasts Feedback to: podcast@sph.com.sg Thank you for your support! ST and BT Podcasts picked up a silver medal for Best Digital Project to engage younger and/or millennial audiences at 2019 Asian Digital Media Awards by Wan-Ifra: https://str.sg/Jw5T See omnystudio.com/listener for privacy information.

Green Pulse Ep 20: Singapore's battle against dual invasion of coronavirus and dengue virus 11:56 mins Synopsis: Green Pulse is an environmental podcast series at The Straits Times which analyses the beat of the changing environment, from biodiversity conservation to climate change. Tune in to this episode to find out about Singapore's efforts to bring forward an increased fight against dengue in 2020, which has so far already recorded double the number of dengue infections compared to last year, in the midst of the developing Covid-19 crisis. Tackling the spread of the two different viruses requires two different approaches. But they both need individual citizens to play their part, whether in terms of stepping up personal hygiene to combat the spread of Covid-19, to reducing breeding grounds for the Aedes aegypti mosquito. These efforts would all help to ensure that Singapore does not have two crises to fight.  In the fourth of a series of podcast episodes based on The Straits Times' The Big Story video, ST’s environment correspondent Audrey Tan chats with a panel of experts to discuss the importance of personal and public hygiene, as Singapore continues its battle against Covid-19. Subjects covered are the drive for cleanliness amid disease, the existing state of hygiene, the need for a greater appreciation of cleaners and life beyond Covid-19. The panel includes: 1. Mr Masagos Zulkifli, Minister for the Environment and Water Resources 2. Professor Wang Linfa, infectious diseases expert at Duke-NUS Medical School 3. Mr Edward D'Silva, chairman, Public Hygiene Council 4. Mr Tai Ji Choong, director of the Department Of Public Cleanliness, The National Environment Agency (NEA) Produced by: Audrey Tan (audreyt@sph.com.sg) & David Fogarty (dfogarty@sph.com.sg) & Ernest Luis Follow Audrey Tan on Twitter Follow David Fogarty on Twitter Edited by: Adam Azlee Discover more Green Pulse podcast episodes on: Spotify: http://str.sg/oCXj Apple Podcasts: http://str.sg/oyLk Google podcasts: http://str.sg/oyLZ Playlist: https://str.sg/JwRh  Website: http://str.sg/stpodcasts Feedback to: podcast@sph.com.sg  Thank you for your support! ST and BT Podcasts picked up a silver medal for Best Digital Project to engage younger and/or millennial audiences at 2019 Asian Digital Media Awards by Wan-Ifra: https://str.sg/Jw5T

Astrophysiker begeben sich auf die Jagd nach der kosmischen Strahlung. Die Menschheit trinkt Bier lange bevor sie sesshaft wird. Und ein lang ersehnter Dengue-Impfstoff wird zum Debakel. [00:22] Begrüßung + „Die Jagd nach der kosmischen Strahlung“ mit Spektrum-Redakteur Robert Gast [14:36] „Bier wurde schon vor Jahrtausenden getrunken“ mit Spektrum-Redakteur Klaus-Dieter Linsmeier [27:09] „Wie ein Impfstoff gegen das Dengue-Fieber zum Debakel wurde“ mit Spektrum-Redakteurin Verena Tang [42:27] Verabschiedung >> Artikel zum Nachlesen: https://detektor.fm/wissen/spektrum-podcast-gammastrahlen-bier-denguefieber

Astrophysiker begeben sich auf die Jagd nach der kosmischen Strahlung. Die Menschheit trinkt Bier lange bevor sie sesshaft wird. Und ein lang ersehnter Dengue-Impfstoff wird zum Debakel. [00:22] Begrüßung + "Die Jagd nach der kosmischen Strahlung" mit Spektrum-Redakteur Robert Gast [14:36] "Bier wurde schon vor Jahrtausenden getrunken" mit Spektrum-Redakteur Klaus-Dieter Linsmeier [27:09] "Wie ein Impfstoff gegen das Dengue-Fieber zum Debakel wurde" mit Spektrum-Redakteurin Verena Tang [42:27] VerabschiedungDer Artikel zum Nachlesen: https://detektor.fm/wissen/spektrum-podcast-gammastrahlen-bier-denguefieber

Session 15 This week, we're joined by Dr. Karen Shackelford from BoardVitals. If you're looking for more prep with your USMLE Step 1 or COMLEX Level 1 training, visit BoardVitals and check out their QBanks for Step 1 and Level 1. Sign up for either 3 months, 6 months, or even 1 month. Your signup will have a vaccine donated through the #GiveVax program. If you sign up for the 3 months and 6 months, you'll get access to Ask a Clinician, where you can connect with the BoardVitals medical experts to answer your content questions. Use the promo code BOARDROUNDS to save 15% off of your purchase. [02:17] About Dr. Karen Shackelford Karen is a former ER clinician. She did her residency in medical school at the University of Mississippi. She eventually moved to Pennsylvania and began working remotely with BoardVitals as a contributor and editor. [03:20] Question of the Week A 35-year-old female patient returned 10 days ago from a mission trip to Nigeria. He was evaluated in the clinic a week ago, complaining of a high fever. She had a rash on the axilla, face, and extremities. The symptoms she had experienced were similar to some she had two years earlier after returning from the same mission trip. Those symptoms resolved with only symptomatic treatment. Today, her husband took her to the emergency department reporting that her fever had resolved two days ago. But she began to complain about abdominal pain and then she appeared very lethargic. On exam, her skin is cool and blocky. She had circumoral sinuses. Her pulse is weak and rapid. And her blood pressure is 80/60 mm Hg. She has a diffused confluent rash and her liver 2 cm below the costal margin. Laboratory studies are significant for a platelet count of 70,000 cells/mL. White blood cell count is 2,000 cells/mL with predominant lymphocytosis. Her serum aminotransferase is elevated. Which of the following is most likely caused by these severe symptoms? (A) Has bacterial super infection (B) Inoculation with a larger viral load (C) Antigenic drift (D) Different viral serotype change [05:08] Thought Process Behind the Answer Antigenic drift is characterized by small changes in the viral structure. It denotes spontaneous changes in the viral type. This is how viruses avoid getting destroyed by vaccines. Serotype is defined as a serologically different strain of microorganism with slight structural differences. They're classified together and have the same type of immune response. But just with a slight variation in their effect on the immune system. The correct answer here is D. The patient, in this case, is her second infection with Dengue Virus but with a different serotype. There are four serotypes of that virus. It's not atypical for somebody to have a mild case that resolves or even asymptomatic initial infection. At that time, the virus presents to a naive immune system. The second time around, it triggers a more significant immune response instead of immunity because of the antigenic differences that the virus responds to. A lot of these viruses are becoming more common in areas that people routinely travel to. A severe viral infection can resolve in hemorrhagic fever and epistaxis, hepatomegaly, circulatory shock. And it resolves through increased capillary permeability because the immune system is having a fluoric response to this second exposure to a slightly different serotype. [10:05] Third Infection If she had a third infection with Dengue Virus, it could be another viral serotype which can be potentially harmful. Although you might have some measure of immunity against the same one. When somebody comes into the office in the Emergency Department with a history of travel to the tropics and they have fibromyalgia, lethargy, and a rash, there are several things that could be wrong with them. Check on Chikungunya fever or dengue fever. They should be considered. But the one that is potentially fatal is dengue. The person could seem to recover. The fever could resolve. They could also become progressively ill and have circulatory collapse several days later. Hence, they should be monitored closely after an episode. The tests for these two are not readily available in those hospitals. So close monitoring should be done if they're coming with acute high fibromyalgia, lethargy, and rash after a trip to the tropics. [11:50] Potential Questions Both fevers are viral and both transmitted by the Aedes mosquito. There's not a vaccine and not a specific treatment. It's just supported. In most cases, the initial infection is asymptomatic or mild asymptomatic. Increased formation in immune complex so she has a pretty flourid response to dengue fever would be the primary mechanism behind it. Again, no specific treatment. Links: BoardVitals (promo code BOARDROUNDS to save 15% off)

We discuss Clone-A-Willy kits. Plus, a gay Waffle House police brutality victim has surfaced but it’s not being smothered or covered. Send us questions, comments, and business inquiries, to hereforitpod@gmail.com We’re on Patreon! Join the #HereForItHive at www.patreon.com/HereForItPod Social Studies - Chikungunya and Dengue Virus https://www.cdc.gov/niosh/topics/outdoor/mosquito-borne/other.html Sexual Health – Reciprocity in Oral Sex Follow us on social media @HereForItPod and hereforitpod.com www.instagram.com/hereforitpod www.twitter.com/hereforitpod www.facebook.com/hereforitpod Don't forget to leave us a comment or review on Apple Podcasts! Search our name in the Podcasts app, click the Reviews tab, click Write A Review. http://apple.co/2y6zmMi

In Cambodia, the number of reported malaria cases, as well as case fatality rates, continue to decrease since the implementation of large scale malaria programs in the country 10 years ago. However, with the introduction and wide distribution of rapid diagnostic tests (RDTs) for malaria, it also turned out that in many of the clinically suspected malaria cases, no malaria parasites could be detected. As a first step towards developing an algorithm for malaria-RDT negative fever management at peripheral health posts, a cross-sectional, prospective, observational study was designed to investigate the causes of acute malaria-negative febrile illness in rural areas of Cambodia. From January 2008 to December 2010, 1475 study subjects were recruited in three different sites throughout the country. Among the study subjects, 1193 were febrile out-patients and 282 were non-febrile individuals who have been recruited as a control group. A battery of test was run on the samples in the central laboratory in Phnom Penh. In 73.2% of the 1193 febrile outpatient samples, at least one pathogen was identified. In 26.8% of these samples the etiology of the fever remained unknown. Most frequent pathogens detected by molecular diagnostics were P. vivax (26.4%), P. falciparum (20.7%), Leptospira (9.5%), Dengue Virus (5.4%), Influenza Virus A (5.9%), O. tsutsugamushi (3.7%), Influenza Virus B (1.8%), Rickettsia (0.2%) and bacteria from blood culture (Salmonella spp., E. coli, S. pneumoniae, E. cloacae) (0.8%). Conclusions: Malaria is still amongst the principal causes of undifferentiated fever in this setting, even though RDTs did not prove sufficient to diagnose cases of low parasitemia and infections with P. vivax. RDT-negative fever cases should be tested for malaria using microscopy or ideally PCR. If malaria is ruled out, diagnostic tools are needed to distinguish between either viral or bacterial etiology of the fever. Leptospirosis and rickettsial diseases showed to play an important role and are easily treatable with the right antibiotics. However, more research and better diagnstic tools are needed to understand and map the incidence of these diseases in Cambodia.