Podcasts about Rickettsia

In This Episode: Nicole Bell, CEO of Galaxy Diagnostics, shares her journey from personal experience with Lyme disease in her family to leading innovation in diagnostics. The connection between tick-borne pathogens and chronic diseases like early-onset Alzheimer's. Why traditional Lyme disease tests often fail and the need for direct detection methods. The latest advancements in testing for Borrelia, Bartonella, Babesia, and other stealth pathogens. The impact of Nicole's "State of Lyme Disease Research" report on the Lyme community. What patients and healthcare providers need to know about cutting-edge diagnostic tools. Why This Matters: An increasing number of studies link flea- and tick-borne pathogens to chronic illnesses affecting the joints, heart, and central nervous system. These infections mimic conditions like lupus and fibromyalgia, making them hard to diagnose without advanced testing. Galaxy Diagnostics offers specialized tests to detect Lyme Borrelia, Bartonella, Babesia, Anaplasma, Ehrlichia, and Rickettsia species—providing a much-needed solution for patients seeking accurate diagnoses. Resources & Links:

In episode 71, we treated a galactic cycle of about 220 million years as a unit of time with which to view evolution. Today, we'll be picking up where we left off and seeing the story through all the way to the end- or rather, the beginning... Sources for this episode: Cox, B. and Cohen, A. (2013), Wonders of Life. London: HarperCollins Publishers. Emelyanov, V. V. (2001), Rickettsiaceae, Rickettsia-like Endosymbionts, and the Origin of Mitochondria. Bioscience Reports 21(1): 1-17. Herron, J. C., and Freeman, S. (2015), Evolutionary Analysis. Harlow: Pearson Education Ltd. Knoll, A. H. (2005), Life on a Young Planet: The First Three Billion Years of Evolution on Earth. Princeton: Princeton University Press. Thain, M. and Hickman, M. (2004), The Penguin Dictionary of Biology (11th edition). London: the Penguin Group. Wernegreen, J. J. (2012), Endosymbiosis. Current Biology 22(14): R555-R561.

On episode #65 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/26 – 10/7/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Exploring viral respiratory coinfections: Shedding light on pathogen interactions (PLoS Pathogens) Bacterial ACG Clinical Guideline: Treatment of Helicobacter pylori Infection (American Journal of Gastroenterology) A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection (Science) The evidence base for the optimal antibiotic treatment duration of upper and lower respiratory tract infections: an umbrella review (LANCET: Infectious Diseases) Population Pharmacokinetic Modeling of Cefepime, Meropenem, and Piperacillin-Tazobactam in Patients With Cystic Fibrosis(JID) Establishment of Amblyomma maculatum Ticks and Rickettsia parkeri in the Northeastern United States (Emerging Infectious Diseases) DETICKT (DETICKT) Early Oral Step-Down Versus Continued Intravenous Antibiotic Treatment of Complicated Intra-Abdominal Infection(Surgical Infections) Fungal The Last of US Season 2 (YouTube) Candida auris: A focused review for emergency clinicians (American Journal of Emergency Medicine) Parasitic Ivermectin-based mass drug administration for scabies in northern India: a single-arm community intervention trial (OFID) Miscellaneous Out-BREAK! : An IDWeek 2023 escape room to break out of the educational mold (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

In this episode, Tick Boot Camp welcomes Ryan Cassata, a 30-year-old musician, activist, and Lyme disease warrior based in Los Angeles, CA. Ryan shares his compelling journey from a bustling music career to grappling with chronic illnesses like Babesiosis and Rickettsia. Through his candid discussion, Ryan provides insights into the challenges of living with tick-borne diseases and the importance of perseverance and community support. Highlights: Introduction to Ryan Cassata: Learn about Ryan's background as an award-winning singer-songwriter and activist, his life in Los Angeles, and his early passion for music. Life Before Lyme: Ryan describes his vibrant life filled with music recording, touring, social activities, and running a music blog, which changed drastically after debilitating symptoms appeared in October 2023. Early Health Challenges: Ryan shares his first experiences with severe joint pain and paralysis in his left toe in 2021, which were initially misdiagnosed as fibromyalgia. Diagnosis Journey: Discover Ryan's path to a correct diagnosis of Babesiosis and Rickettsia shortly after his 30th birthday, following consultations with at least six doctors. Treatment Regimen: Ryan details his ongoing treatment since November 2022, including supplements, ozone and UV light therapy, anti-malarial and anti-parasite drugs, herbs, IV glutathione, and CBD, with plans to start infrared sauna therapy. Impact on Life and Career: Ryan discusses the significant impact of his illnesses on his ability to work, tour, record music, and socialize, sharing how he navigates these challenges. Advice for Others: Ryan encourages those battling Lyme disease to hold on, seek second opinions, visualize overcoming the illness, and rely on loved ones for support. Educational and Professional Background: Master of Art in Social Transformation from Pacific School of Religion, graduated May 2023 ASCAP award-winning singer-songwriter Recording Academy Voting Member (GRAMMYs) Certificate of Congressional Recognition Quotes from the Episode: "Picture yourself as a superhero and the mission is to beat the illness. That has been helping me get through." "It's okay to cry. It's a very stressful illness." "Wear the proper clothing and take the extra precautions when hiking or being in areas where ticks are often present." Conclusion: Ryan Cassata's episode is a testament to resilience and the power of community in the face of chronic illness. His story provides hope and practical advice for those dealing with Lyme disease and other tick-borne illnesses. Stay tuned for more inspiring stories and valuable insights from the Tick Boot Camp Podcast. Thank You: A special thanks to Ryan Cassata for sharing his journey and to our co-host, Maria Mooney, for contributing to this enriching conversation. Stay Connected: Subscribe to the Tick Boot Camp Podcast for more episodes featuring stories of perseverance, hope, and valuable information on Lyme disease and tick-borne illnesses.

On episode #57 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/6 – 6/19/24. Host: Daniel Griffin Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Is letermovir or valganciclovir better to prevent CMV in kidney transplant recipients (JID) CMV antiviral therapy (GoodRx) Prevalence of and risk for CMV reactivation during COVID-19 pneumonia (PLoS One) Sofosbuvir off-label yellow fever treatment (OFID) Bacterial Preventing resistant gram negative bacteria through beta-lactam de-escalation in sepsis patients (CID) Competing risk analysis, survival analysis that aims to correctly estimate marginal probability of an event (Columbia University) Continuous or intermittent b-lactam infusion for critical sepsis (JAMA Network) Prolonged vs Intermittent Infusions of β-Lactam Antibiotics in Adults With Sepsis or Septic Shock (JAMA Network) Phoenix sepsis score and risk in children with cancer (JAMA Network) New recognized spotted fever group Rickettsia in Northern California (Emerging Infectious Diseases) Screening for mycobacterium tuberculosis (Transplant Infectious Disease) Fungal Potential sexual transmission of Tinea pubogenitalis from TMWII (JAMA Dermatology) Household transmission of tinea infection (OFID) Drug-resistant oral candidiasis in HIV infected patients (BMC Infectious Disease) Parasitic Handheld digital microscope for rapid and comprehensive screening for urogenital and gastrointestinal schistosomiasis (American Journal of Tropical Medicine and Hygiene) Scorecard approach to eliminate onchocerciasis (Am J Trop Med Hyg) Miscellaneous Association between antibiotic receipt and provider rating (OFID) Infectious diseases and infection control prevention strategies when on ECMO (Perfusion) Music is by Ronald Jenkees

In 1901, the state of Montana organised for scientists and doctors to investigate a mysterious illness from the Bitterroot Valley called ‘Black measles' and ‘Black typhus'. People of all ages were affected but predominantly those who worked in the brush and were exposed to tick bites. The investigators called it ‘tick fever' and this particular strain had a mortality rate over eighty percent. Today this disease is known as Rocky Mountain spotted fever. In Australia, it is sometimes called ‘spotted fever' or ‘Queensland tick typhus'. It is caused by an obligate intracellular bacterial micro-organism (needs a cell to survive). This organism is very difficult to culture and can be even more difficult to diagnose but surprisingly easy to treat. Rickettsial disease is an under-recognised infection and important in the differential diagnosis of any patients presenting with fevers, headaches and rash. This is the story of Rickettsia Our special guest: Our special guest is Professor Stephen Graves who is a medical microbiology and founder of the Australian Rickettsial Reference Laboratory (ARRL). He specialises is infectious diseases transmitted by ectoparasites such as ticks, lice, fleas and mites. This Medical Life podcast is available on all podcasting services and Spotify. See omnystudio.com/listener for privacy information.

Chronic Fatigue Syndrome is now officially known as Myalgic Encephalomyelitis (ME/CFS). The CDC believes this is a vastly under-diagnosed condition. In this episode, you'll learn:--Why Chronic Fatigue Syndrome was a diagnosis that did not get much respect. And why the name change was encouraged by government agencies in 2015.--How the Centers for Disease Control believes that 90-95% of cases are not being diagnosed or treated properly.--That even children can be affected by ME/CFS, though it is more common in women, minorities, and those between the ages of 33 and 50.--Why a person's "phase angle" (or electromagnetic charge around the cells) can indicate the condition.--How one-fourth of those with ME/CFS are bedridden and unable to function. And how the Social Security department wanted to create more awareness of this disease because it costs between $17 and $24 billion annually.--The symptoms of ME/CFS, including: severe fatigue for at least six months, cognitive impairment, muscle or joint pain, headaches, swelling of lymph nodes, sore throat, and complete exhaustion after any kind of mental or physical work.--The underlying viral infections that can cause ME/CFS, including: Epstein-Barr virus, Lyme Disease, Rickettsia, Retroviruses, Bornaviruses, Fungi and Mycoplasma, Flu viruses, Xenotropic murine leukemia virus-related virus (XMRV), and Cytomegalovirus.--Why The Structure-Function approach used by Holistic Integration is "really the only way of getting success" with this disease process. And why there is really no effective Disease Care approach to ME/CFS.--How Homeopathy stimulates the immune system to combat the underlying viruses that cause ME/CFS. And why those with ME/CFS "do not do well" with pharmaceuticals and antibiotics.--The effectiveness of supplementation, herbals, Chiropractic adjustments, Acupuncture, and therapeutic massage for ME/CFS patients. And the importance of blood analysis every three months for these patients.www.TheVoiceOfHealthRadio.com

Tickborne illnesses are often misunderstood and misdiagnosed. Dr. Prather has seen all the most common ones in his office, but finds more Rickettsia infections in Indiana. In this episode, find out:—Why a tick must be on you for several hours to transmit a Tickborne illness.—How to properly remove a tick. And why it is helpful to keep the tick in case you get sick in the future.—The natural, non-toxic spray Dr. Prather recommends to avoid bug bites. —How all ticks do not transmit Lyme Disease. And the kind to look out for that does.—Why using antibiotics as the first treatment after a tick bite is actually discouraged by the CDC. And how Dr. Prather can usually look at a bite and determine whether it will become an infection. —The "latest and greatest" lab tests Dr. Prather uses to properly diagnose a patient's infection. And why the test used for Lyme Disease is described as "so-so". —The Homeopathic treatments that Dr. Prather considers to be his "secret weapon" for success with Tickborne illness. Plus, the nutraceuticals and herbal supplements that make "an incredible difference" in the healing and recovery of the body from Tickborne illness.—How joint pain is a standard indicator of Tickborne illness. And how Chiropractic is important for Tickborne illness because the infection often causes a structural misalignment that "must be fixed to be able to get the body better".—Why Dr. Prather "absolutely requires" Acupuncture for his Tickborne illness patients because it makes an "incredible and immediate difference"". —Plus, hear the details about our upcoming Holistic Integration Open House on Lyme Disease and Tick-borne Diseases on Wednesday, September 27th at 6 p.m. And how you can receive 20% off of tick-borne diagnostics for attending.http://www.TheVoiceOfHealthRadio.com

Join Jessica Stahl, an epidemiology graduate student and former CDC contractor, as she deep dives into the fascinating world of Typhus. Sources: https://www.ncbi.nlm.nih.gov/books/NBK448173/ https://www.montana.edu/historybug/napoleon/typhus-russia.html#:~:text=Just%20one%20month%20into%20the,followed%2C%20claiming%206%2C000%20French%20casualties.  https://wwwnc.cdc.gov/eid/article/29/4/ac-2904_article#:~:text=Major%20typhus%20epidemics%20took%20place,%2C%20including%20typhus%2C%20was%20challenging.  https://www.cambridge.org/core/services/aop-cambridge-core/content/view/0AF993E555D30A9F8DCD864F4DDD4344/S0025727300058725a.pdf/div-class-title-typhus-and-its-control-in-russia-1870-1940-div.pdf  https://www.cdc.gov/typhus/index.html Article about the Typhus vaccine in WWII: https://www.politico.com/magazine/story/2014/07/lice-doctor-lviv-nazi-germany-109255/

El día de hoy en A tu Salud hablaremos sobre "Todo lo que necesitamos saber sobre la picadura de garrapata (rickettsia)" con la Dra. Angélica María Escárcega, Profesora Investigadora UACJ-ICB#UACJ #SOMOSUACJ #uacjradio #salud #garrapatas #Rickettsia #mascotas

Locución: Mayra Carrillo y el Doctor Miguel Ángel Ochoa. Sistema Jalisciense de Radio y Televisión. Visita: www.jaliscoradio.com

Nos últimos dias, a morte de quatro pessoas por febre maculosa no estado de São Paulo chamou atenção para os riscos da doença. A febre maculosa é uma doença transmitida pela picada do carrapato infectado com a bactéria do gênero Rickettsia. A transmissão acontece quando o animal infectado fica aderido ao corpo da pessoa ou também pela penetração das bactérias em lesões de pele, através do esmagamento do carrapato. A febre maculosa é uma doença infecciosa que acomete e pode levar a óbito tanto humanos quanto alguns animais, embora pela literatura científica seja um achado raro. Transmitida pela picada do carrapato-estrela, que pode ser encontrado em animais de grande porte, como capivaras e cavalos, cães, aves domésticas e roedores. Segundo a Diretoria de Vigilância Epidemiológica de Santa Catarina (DIVE/SC) o estado tem registro de quadros leves de febre maculosa. O estado registrou 41 casos de febre maculosa em 2022. Neste ano, até agora, já são 18 casos confirmados. Durante entrevista ao Cruz de Malta Notícias desta segunda-feira (19) o Professor do Curso de Medicina Veterinária do Unibave, Mauro Maciel de Arruda, que inclusive já atuou no Ministério da Saúde na área de zoonoses, trouxe informações sobre a Febre Maculosa. Ouça abaixo a íntegra da entrevista:

Doença infecciosa febril aguda, a febre maculosa é transmitida por carrapatos infectados com a bactéria Rickettsia rickettsii. Ela é endêmica na região Sudeste, onde as taxas de letalidade passam de 50%, de acordo com dados do Ministério da Saúde. Saiba como se prevenir.

Doença infecciosa febril aguda, a febre maculosa é transmitida por carrapatos infectados com a bactéria Rickettsia rickettsii, presente principalmente no carrapato-estrela, de acordo com o Ministério da Saúde. A doença foi confirmada na terça-feira (13) como causa da morte da dentista Mariana Giordano e de seu namorado, o piloto de automobilismo Douglas Costa. Conheça sintomas e como se prevenir.

Buenos días, jueves 25 de mayo. Le presentamos la información para empezar el día. 1.- Luego de que se diera a conocer la muerte de un menor por Rickettsia enfermedad transmitida por la picadura de una garrapata, José Antonio Adame, director de Salud Municipal de Gómez Palacio, anuncio que tanto en colonias de esta ciudad y planteles educativos serán fumigados.  2.- Con el fin de mejorar la seguridad y el tiempo sea menor en la atención para una emergencia, el director de Seguridad Pública Municipal de Torreón, César Perales, informó que se tiene una nueva caseta de vigilancia en la colonia Provitec, así mismo detalló que cubrirá diversos sectores de esta zona. 3.- Ante el próximo periodo de graduaciones que están programadas para mediados del mes de junio, comercios de joyería, boutiques, arreglos florales y de globos, anunciaron estar listos para estos eventos, así mismo esperan que se tengan buenas ventas. 4.- De acuerdo a Raúl Rodríguez García, director de Inspección y Verificación Municipal, dio a conocer que las quejas de vecinos ruidosos han aumentado en la ciudad de Torreón, por lo cual el Ayuntamiento planea dialogar con los ciudadanos para fomentar una mejor convivencia y respeto hacia los demás. 5.- Hoy es el Día Internacional de los Niños Desaparecidos y su objetivo es que las autoridades tomen conciencia para que se agilice la búsqueda de los menores, así también prevenir y reducir estos actos que van en aumento. Acompáñenos con toda la información en punto de las ocho de la noche por Meganoticias.

Buenos días, viernes 19 de mayo. Le presentamos la información para empezar el día. 1.- Ante la primera muerte del año de un niño de cuatro años de edad por complicaciones de la enfermedad Rickettsia, Luis Fernando Olvera Martínez, jefe de la Jurisdicción Sanitaria Número Dos de Gómez Palacio, dio a conocer que se estableció un cerco sanitario a los alrededores del domicilio del pequeño esto con el fin de evitar nuevos casos.  2.- Debido a los constantes apagones y contaminación auditiva vecinos de la colonia Rincón la Rosita en Torreón, solicitan a las autoridades correspondientes acudan a este sector ya que también manifestaron se han visto afectados por el ruido, además de que también algunos de sus aparatos electrónicos han resultado dañados. 3.- Luego de que el Sistema Descentralizado de Agua Potable y Alcantarillado (Sideapa) de Gómez Palacio, ha extraído pañales, tampones, papel higiénico, toallas sanitarias, colillas de cigarros entre otros objetos, exhortan a la ciudadanía a no vaciar estos residuos en los inodoros ya que afectan el funcionamiento de la red de drenaje. 4.- Hoy es el Día Mundial de la Donación de Leche Materna, fecha que rinde homenaje a las madres que participan en esta noble acción de donar a los recién nacidos que no pueden ser amamantados por diversas causas, como enfermedades o intolerancia a las fórmulas de leche artificial. 5.- Temperaturas mínimas de los 17 y máximas de los 34 grados centígrados, cielo nublado a despejado, viento y posibilidad de precipitaciones, pronostica la Comisión Nacional del Agua (Conagua), para hoy y los próximos días en la Comarca Lagunera. Acompáñenos con toda la información en punto de las ocho de la noche por Meganoticias.

Hablemos de Garrapatas y RickettsiaEntrevista a la Mtra. Carolina MontelongoResponsable del Hospital Veterinario Universitario#UACJ #SOMOSUACJ #uacjradio #garrapatas #rickettsia

PODCAST HIGHLIGHTS: Coming Soon https://youtu.be/Rd7WJuvSBk0 Transcript from Webinar: Coming Soon... REFERNCES: Coming Soon... Dr. John Nieters L.Ac, DAOM, is an acupuncturist, Chinese herbalist, functional medicine, writer, teacher, and leader in the community. In this episode, John talks about his experience with the importance of finding your vision and purpose in life, in order to create...... Continue Reading →

Dana Parish interviews Dr. Kenneth Liegner, a Board Certified Internist practicing in Pawling, New York. He has been on the front lines of treating chronic Lyme and related infections since 1988. He has published in peer-reviewed scientific journals and is the author of In the Crucible of Chronic Lyme Disease—Collected Writings & Associated Materials.

La rickettsia es una enfermedad transmitida por garrapatas y que fue diagnosticada en la menor que murió en Nuevo León tras ser mordida por uno de estos ácaros.

Juniper, the only woman I've had a one night stand with, opens up about her chronic illness Rickettsia, a bacterial infection caused by tick bites that can lead to chronic fatigue and other physiological problems. Content warning for chronic illnesses. We talk about the deep depression and complete loss of hope that can come in certain moments. Juniper describes this experience for her as a “spiritual death” that eventually got easier to manage. We talk about isolation as well. It's an intimate conversation, just as you've come to expect from us. --- Send in a voice message: https://anchor.fm/intimate-interactions/message

On episode #16 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 11/9/22 – 11/23/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Recommendations of the advisory committee on immunization practices for measles, mumps, rubella (CDC) Bacteremia with anaerobic bacteria and association with colorectal cancer (CID) Factors impacting the yield of image-guided biopsy in native vertebral osteomyelitis (OFID) Development of a clinical prediction score to inform tuberculosis treatment among children with HIV (OFID)  First detection and molecular identification of Rickettsia massiliae, a human pathogen (PLOS) Short-course vs long-course antibiotic therapy for children with nonsevere community-acquired pneumonia (JAMA) The timing of preoperative urinary tract infection influences the risk of prosthetic joint infection following primary total hip and knee arthroplasty (JOA) Recurrent candidemia: trends and risk factors among persons residing in 4 US States (OFID) Spread of Sporothrix spp through respiratory droplets from infected cats (Medical Mycology) Comparison of mold active triazoles as primary antifungal prophylaxis in patients with newly diagnosed acute myeloid leukemia (CID) Geographic distribution of dimorphic mycoses in the United States (CID) Knowledge, experiences, and practices of women affected by female genital schistosomiasis in rural Madagascar (PLOS NTDs) Dynamic immune profile in French Toxoplasmosis patients  White-Tailed deer are susceptible to the agent of classical sheep scrapie after experimental oronasal exposure (JID) The Lanzhou Brucella Leak: The largest laboratory accident in the history of Infectious Diseases (CID) Music is by Ronald Jenkees

Rocky Mountain Spotted Fever A tick borne disease Rickettsia rickettsii Causes small vessel vasculitis Can cause serious damage to internal organs, can be lethal My be found throughout the Western Hemisphere Clinical Presentation Initial symptoms High Fever Nausea / vomiting Severe headache Muscle pain Later signs and symptoms Maculopapular rash, occurs 2-5 days after fever, […] The post EP 100 Bacterial Infections Part 2 & an app I’m loving appeared first on Physician Assistant Exam Review.

Laura Perry is a 37-year-old myth busting Integrative Health Practitioner from Richmond, Virginia. Despite suffering from unwellness for most of her life, she succeeded in securing a very stable and lucrative job in corporate America. During her lengthy diagnostic journey, she treated with 15 allopathic doctors who misdiagnosed her “over and over again.” In 2019, she abandoned the western medical system and utilized Bioresonance testing. She tested positive for “Borrelia, Babesia, Bartonella and Rickettsia.” Finally securing a diagnosis permitted Laura to treat her “own Lyme by addressing immune system dysregulation.” First, she remediated mold contamination in her home. Next, she had to address parasites and cell danger response. Thereafter she moved “on to treating with things like the parasite zapper and CellCore IS tinctures” for Lyme disease and co-infections. After much trial and error, Ms. Perry developed a “muscle testing method that provides the ability to hone in on what is driving symptoms very quickly.” With the support of her entrepreneurial husband, she left corporate America to share her method by building Revealing Healing. Revealing Healing is a program designed to help “those who want to heal and to do it themselves” with gentle guidance from Ms. Perry for the first few months. If you would like to learn more about how the 12 week Revealing Healing program can provide you with the tools and information required to foster self-healing from Lyme disease, then tune in now!

Erin Scott contracted a rare bacterial disease called Murine typhus, which is a Flea-borne disease caused by a bacteria called Rickettsia typhi. She was admitted to hospital whereupon they placed her into an induced coma due to the organ failure. She then required years of speech therapy as a part of the aftermath of this life changing condition which is most commonly found in California and Texas.

Cat sniffing a cat cake Dr. Don and Professor Ben talk about the risks of eating cake licked by a cat.Dr. Don - risky ☣️ Professor Ben - risky ☣️ Goudy Bold Italic on Twitter: "@benjaminchapman @bugcounter @firstbornspawn Risky or not: cake that a cat has been licking. Not frosted, plain top with occasional crumb topping. (Extra credit: gross or not?) Just happened, is it rude to not want to take home leftover cake after your hosts' cat has licked it?" / Twitter Cats | Healthy Pets, Healthy People | CDC 'I'm not a cat': lawyer gets stuck on Zoom kitten filter during court case - YouTube Anaplasma, Ehrlichia and Rickettsia species infections in cats: European guidelines from the ABCD on prevention and management - Maria Grazia Pennisi, Regina Hofmann-Lehmann, Alan D Radford, Séverine Tasker, Sándor Belák, Diane D Addie, Corine Boucraut-Baralon, Herman Egberink, Tadeusz Frymus, Tim Gruffydd-Jones, Katrin Hartmann, Marian C Horzinek, Margaret J Hosie, Albert Lloret, Hans Lutz, Fulvio Marsilio, Etienne Thiry, Uwe Truyen, Karin Möstl, 2017 Detection of Bartonella henselae in domestic cats' saliva

Dr. Don and Professor Ben talk about the risks of eating cake licked by a cat. Dr. Don - risky ☣️ Professor Ben - risky ☣️ Goudy Bold Italic on Twitter: “@benjaminchapman @bugcounter @firstbornspawn Risky or not: cake that a cat has been licking. Not frosted, plain top with occasional crumb topping. (Extra credit: gross or not?) Just happened, is it rude to not want to take home leftover cake after your hosts' cat has licked it?” / Twitter Cats | Healthy Pets, Healthy People | CDC ‘I'm not a cat': lawyer gets stuck on Zoom kitten filter during court case - YouTube Anaplasma, Ehrlichia and Rickettsia species infections in cats: European guidelines from the ABCD on prevention and management - Maria Grazia Pennisi, Regina Hofmann-Lehmann, Alan D Radford, Séverine Tasker, Sándor Belák, Diane D Addie, Corine Boucraut-Baralon, Herman Egberink, Tadeusz Frymus, Tim Gruffydd-Jones, Katrin Hartmann, Marian C Horzinek, Margaret J Hosie, Albert Lloret, Hans Lutz, Fulvio Marsilio, Etienne Thiry, Uwe Truyen, Karin Möstl, 2017 Detection of Bartonella henselae in domestic cats' saliva

We're back with our first episode of Season 5, and we're starting off with a bang! Epidemic typhus, that friend of war and famine, may have caused more wartime deaths than all battles combined, and though it may seem like a disease relegated to the past, typhus only needs a minor disruption to turn it into a scourge of the present. In this epic season opener, we turn our sights to the louse-transmitted Rickettsia prowazekii, first diving into the strange and terrible biology of this bacterium before exploring the deep history of this tiny but mighty pathogen. The vast story of typhus takes us on a journey on a ‘coffin ship' of the Great Irish Famine, through musings of the origins of human body and head lice, to German-occupied Poland during WWII with tales of vaccine sabotage and lice feeding, and finally to the present day, where we discuss the very real threat that epidemic typhus continues to pose. Check out this episode for all you ever wanted to know about epidemic typhus and more! See omnystudio.com/listener for privacy information.

“Mary has died of Typhoid Fever”. Ah, yes. If you are of a certain generation, you remember being met with these abrupt notifications while playing Oregon Trail. While this game taught generations of young people about Western migration in 19th-century America, it also familiarized them with various diseases…and, how to avoid getting run over by wagon wheels. This month, our hosts are exploring the root of the cause – diving into species and subspecies of Salmonella. More about Salmonella: CDC's summary of Salmonella Salmonella Nomenclature Mary Mallon (1869-1938) and the history of typhoid fever Stay tuned for more episodes, posting on the first Thursday of each month. Subscribe to our show wherever you get your podcasts and find more info at weebeastiespodcast.com     The Wee Beasties podcast is a production of Nephros, Inc., a company committed to improving the human relationship with water through leading, accessible technology.  *** SHOW TRANSCRIPT: Christian:  I am back with Dr. Kimothy Smith. Kimothy, welcome back! Kimothy:  Thanks, Christian. What's new? Christian:  Well, I've been combing through the annals of gastroenterology in search of the origin of “Typhoid Mary” and learned a few things I'd like to share. Kimothy:  By all means. What ya got? Christian:  Alright, so check it out, in case you're not current on your NYC history or your only reference for Typhoid fever was that Oregon Trail game back in the late '80s…and this is literally from the Annals of Gastroenterology…I'll throw a link in the show notes – Typhoid Mary was the name eventually given to a woman named, Mary Mallon who lived in NYC in the early 1900s and became notorious as a healthy carrier of Salmonella thypi – the bacterium that causes Typhoid fever. She was an immigrant, not necessarily well off, and was employed as a cook for wealthy families. Now, this was before a vaccine was available and before antibiotics. An investigation had started because there were many people getting sick with a fever, and the investigator trying to track down the source noticed there were pockets of families employing the same cook. Mary was leaving after the infection had occurred to move on to a new family to cook for them. In the end, there were 122 people infected, 5 dead. And that year over 3,000 people in NYC had become infected in 1907 – she was apparently the source. What's interesting is that there was no tracking mechanism in place, so investigations had to be done just by a small group or single man. There was an assumption that a microorganism was suspected of being responsible, but nobody knew why. The investigation really corroborated that hypothesis which eventually came from a team of veterinary scientists. So, in 1880, this guy Daniel Elmer Salmon ended up naming Salmonella typhi as a consequence of this investigation. Kimothy: Sticking with your history bend for a minute, this is not so long after the cholera plague in London. Germ theory was still a controversial thing, they thought it was neighbors. So, go vets! Real doctors treat more than one species. Kimothy:  So, if you haven't inferred already, we're going to give you a snapshot of Salmonella today. Salmonella enterica, specifically. Christian:  Yeah, so…a query sir.  As I was sifting through literature, I didn't see a lot of mention of enterica early in the investigation of Typhoid fever.  Can you summarize how Salmonella enterica became the catch-all for all the varieties of Salmonella? Kimothy:  Yeah, it's a bit unusual because as you said, Christian, the initial outbreak investigation resulted in named in Salmonella typhi and now we have Salmonella enterica. It's important to remember that science naming conventions are like kaleidoscopes – the contents remain the same, but the picture and how it's described change depending on who's holding the instrument. Such has been the reshuffling with Salmonella. Most of the scientific community now breaks Salmonella into two species Salmonella bongori and Salmonella enterica into 6 subspecies and over 2600 serotypes. But essentially it comes down to two groups – Salmonella that causes gastroenteritis and then those that cause enteric fevers. Christian:  Which patient populations are most at risk for acquiring Salmonella? Kimothy:  The CDC estimated that Salmonella causes 1.2 million illnesses and 450 deaths annually in the US.  Anyone can become infected with the bacteria – fecal-oral and food & water are the most common routes. The populations at greatest risk are typical demographic we've discussed for all our opportunistic pathogens – those under the age of 5 and over the age of 65, and those with weakened immune systems. Christian:  And how does it present? Kimothy:  So, the gastrointestinal infection that results when you ingest the bacteria is Salmonellosis, and it presents exactly how you would expect for a pathogen that survives in your GI tract – fever, abdominal cramps, and diarrhea. Symptoms manifest within about 12-72 hours and typically last about a week. You can take antibiotics, but most people will be able to recover without pharmaceutical intervention. Typhoid fever is, as you might expect, slightly different.  Patients become symptomatic gradually and once a fever presents it is accompanied by extreme fatigue, usually a skin rash or skin discoloration, headaches, abdominal pain, and constipation. Without medical intervention, the fever can be fatal.  But it can easily be treated with antibiotics, such as azithromycin. Christian:  And if you really believe in preventative medicine folks, you can always get the vaccine.  Also, Typhoid fever shouldn't be confused be typhus, right? Two totally different pathologies. Typhus is caused by Rickettsia, a different gram-negative bacterium that spreads itself around to humans hitching a ride on lice and fleas. I digress. Tell me about Cell morphology and other unique descriptions associated with Salmonella. Kimothy: Gram-negative rods, motile with flagella, about 0.4 - 0.7 micron in size. Christian:  Quick question before I let you go: do both varieties of Salmonella transmit the same? Kimothy:  So, good question. No, they do not. The variety that causes Typhoid fever is spread from human to human only and the variety that results in gastroenteritis is transmitted in food or water. Christian:  Copy that, so we're in the clear for acquiring Typhoid fever a la hospital drinking fountains. Kimothy, as always, thanks so much for the chat today. Kimothy:  You bet, Christian.

The TWiP quadfecta solves the case of the Traveler With Watery Diarrhea, and reveals that a heat-shock response regulated by a transcription factor protects human malaria parasites from the high temperatures of fever. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Subscribe (free): iTunes, Google Podcasts, RSS, email Links for this episode PWB on Facebook, Instagram, Twitter Malaria parasite resists fever due to heat shock response (Nat Micro) Malaria beats the heat (Nat Micro) Letters read on TWiP 198 Become a patron of TWiP Case Study for TWiP 198 31 yo woman, previously healthy, traveled to Tanzania, went on 11 day long safari. One week later, at home, developed fever and severe headache, went into hospital. Thick blood smears negative, physical exam normal, small purple lesion near buttocks. Started on treatment for African tick bite fever. Did not get better, lesion grew in size. Biopsy of lesion, nothing remarkable on microscopy. Improved, sent home, 10 days another bout of fever that went down in 2 days. Lesion healed. PCR for plasmodium, Borrelia negative, but seroconverted for Rickettsia. Went home, a week later another 3 day bout of fever.    Send your case diagnosis, questions and comments to twip@microbe.tv Music by Ronald Jenkees

Keneler, balıklar dışında, omurgalıların vücuduna yerleşim göstererek hastalık oluşturabilen ektoparazitlerden biridir.​1​ Nemli ortamları, çalılık ve çayırlık alanları mesken edinmiş keneler, bu arazi koşullarında gerek tarım ve hayvancılık gerekse de avlanma ve dağcılık gibi doğa sporları faaliyetlerinde bulunan kişilere yapışabilir ki zaten olan da bundan sonra olur. Yapılan çalışmalarda, kene maruziyeti ile acil servislere başvuruların genellikle köy ve ilçe merkezlerinin kırsal kesimlerinden olması da bunu destekler niteliktedir.​2​ Ayrıca çiftlik hayvanlarının ve kuşların göç yolları boyunca da taşınarak coğrafi dağılım çeşitliliği oluşturabilirler. Soğuk aylarda toprak altında varlığını sürdüren keneler, ortam ısınınca gün yüzüne çıkmaya başlar. Sıcak mevsimlerde artış gösteren vektöryal hareketlilik, ilkbahar ve özellikle de yaz aylarında kene vakalarını acil servislere taşımaya başlar.​3,4​ Her Kene KKKA Yapmaz, Yaparsa da Sadece KKKA Yapmaz! Kene denince aklımıza ülkemiz adına en çok Kırım Kongo Kanamalı Ateşi (KKKA) gelmektedir. Bununla ilgili Dr. Burak Bekgöz'ün daha önce yayınlamış olan yazısını incelemenizi öneririm. Ancak KKKA'nın yanında tüm dünyada keneler ve kenelerle bulaşan etkenlerin oluşturduğu son derece önemli klinik bulgularla seyredebilen hastalıklar mevcuttur. Keneler bu hastalıkları taşıdıkları çeşitli mikroorganizmaları insan kan dolaşımına entegre etmek suretiyle yapmaktadır. İnsanlara bakteri bulaştırırlar ve Tularemi, Lyme hastalığı, Q ateşi gibi hastalıklar yaparlar. Virüs bulaştırırlar ve bu yolla Kırım Kongo Kanamalı Ateşi, Kene Kaynaklı Ensefalit (TBE) hastalığı, Kolorado Kene Ateşi gibi hastalıklar yaparlar. Rikettsial bulaşla benekli ateş grubu hastalıklar, protozoal bulaşla Babessiosis oluştururlar. Ayrıca sadece kene teması ile değil, hasta insan ve hayvanlara ait vücut sıvılarıyla temas, nazokomiyal ve cinsel yolla da bu hastalıklara sahip olmak mümkündür.​5,6​ Ciltte oluşturdukları lezyonlara sekonder gelişen enfeksiyonlar da cabası! BAKTERİ  Tularemi (Francisella tularensis)Lyme Hastalığı (Borrelia burgdorferi)Q ateşi (Coxiella burnetti)VİRÜSKırım Kongo Kanamalı Ateşi (Nairo virüs)Kene Kaynaklı Ensefalit Hastalığı (flavivirüsler)Kolorado Kene Ateşi (coltivirus)BENEKLİ ATEŞ GRUBU RİKETTSİYOZLAR  Rickettsia rickettsii (kayalık dağlar benekli ateşi)Rickettsia conorii kompleksi (Akdeniz benekli ateşi)Rickettsia sibirica (Kuzey Asya kene tifüsü)Rickettsia australis (Queensland kene tifüsü)PARAZİT (BABESSİOZİS)Babesia microtiBabesia bovisBabesia divergensKene Kaynaklı Bazı Hastalıklar ve Etkeni Olan Mikroorganizmalar Hepsinden ziyade, keneler kan emerken salgıladıkları toksik maddeler sayesinde anaflaksiye gidecek kadar bile alerjik reaksiyonlara neden olabilmektedir. Bu aşamada anaflaksi tanınmalı ve hızlı bir şekilde yönetilmelidir. Böylesine ciddi klinik tablolara yol açabilen bu ektoparazitlerle uzun yıllar mücadele edilmiş ancak hiçbir yöntem kenelerin dünya üzerinden eradikasyonunu mümkün kılamamıştır. Bu nedenle kene ve keneyle bulaşan hastalıklar çoğunlukla ilk başvuru yerleri olan acil servisler için klinik açıdan önem arz etmeye devam etmektedir. Acil Serviste Kene Çıkarılması Kenelerin ısırıkları ağrısızdır ve çoğunlukla insanlar tarafından fark edilmez.​7​ Fark edildiğinde ise mümkün olan en kısa zamanda olası hastalık bulaşını engellemek için uygun bir şekilde (vücuda temas ettiği en yakın yerden, çıplak elle dokunmadan ve herhangi bir kimyasal madde kullanmadan, nazikçe ve sabit bir kuvvet uygulayarak) çıkarılmalıdır. Bu bağlamda kenenin vücuda temas süresini olabildiğince azaltmak adına önerilen şayet yapabilecekse kişinin kendisinin keneyi çıkarmasıdır. Çıkaramayacaklarını düşünen hasta ve hasta yakınlarına önerimiz ise en yakın sağlık kuruluşuna ya da acil servise ivedilikle başvurmalarıdır. Keza yapılmış çalışmalarda, kene çıkarma işlemi genellikle sağlık çalışanlarına kalmakta; belki de bu sebeple işlemdeki başarı yüzdesi sağlık çalışanlarında daha...

Join Yvonne Brandenburg, RVT, VTS SAIM and Jordan Porter RVT, LVT, VTS SAIM as we talk about: The big four!!! Tick borne bacterial diseases; anaplasmosis, ehrlichia, lyme, and rocky mountain spotted fever, OH MY! Ever wonder how ticks transmit these diseases? Well you're about to find out, prepare to get squiggy.    Question of the Week Have you had a personal experience with one of these tick borne illnesses, like human experience.  Leave a comment at https://imfpp.org/episode89   Resources We Mentioned in the Show  Canine Rocky Mountain Spotted Fever. Parasitology Compendium. July 2005 (Vol 27, No 7). Rochelle M. Low , DVM , Jennifer L. Holm , DVM , DACVECC  https://www.vetfolio.com/learn/article/canine-rocky-mountain-spotted-fever Rocky Mountain Spotted Fever in Dogs. (Rickettsia rickettsii Infection). Janet E. Foley , DVM, PhD, University of California, Davis. https://www.merckvetmanual.com/generalized-conditions/rickettsial-diseases/rocky-mountain-spotted-fever-in-dogs    Anaplasmosis. Becky Lundgren, DVM. Date Published: 04/08/2014. https://veterinarypartner.vin.com/default.aspx?pid=19239&id=6191808 Merrill, L. (2012). Small Animal Internal Medicine for Veterinary Technicians and Nurses. Ames: Wiley - Blackwell.   Thanks so much for tuning in. Join us again next week for another episode!  Want to earn some RACE approved CE credits for listening to the podcast? You can earn between 0.5-1.0  hour of RACE approved CE credit for each podcast episode you listen to.    Join the Internal Medicine For Vet Techs Membership to earn and keep track of your continuing education hours as you get your learn on!   Join now! http://internalmedicineforvettechsmembership.com/   Get Access to the Membership Site for your RACE approved CE certificates Sign up at https://internalmedicineforvettechsmembership.com  Get Access to the Technician Treasure Trove  Sign up at https://imfpp.org/treasuretrove    Thanks for listening!  – Yvonne and Jordan 

Experts predict that the summer of 2021 will be a "Tick Bomb".  So this week, Dr. Prather talks about Tick-borne Diseases, such as Lyme Disease and Rickettsia.  In this episode, you'll discover: --Why it is hard to diagnose tick-borne disease, frustrating both patients and doctors as it mimics other diseases.  And why doctors often roll their eyes when they hear the term Lyme Disease and the controversy over testing for it. --How tickborne disease can lead to an autoimmune disease. And how Lupus patients are often misdiagnosed when they really have an infection. --How immune-suppressing drugs are often given that make the problem MUCH worse. --That Rickettsia infection is far more common in Indiana than Lyme Disease and that they have to be treated differently. And how most patients who say that they have Lyme Disease actually have something else. --Why dog owners are at a higher risk for such diseases. And why you should not allow your dog to sleep on your bed. --How Homeopathy can make a huge difference for patients who have exhausted every antibiotic known to man. --How getting the gut working properly is the key to rebuilding a person's immune system. --Why Dr. Prather says no one is better at determining how to battle an infection than the body itself...IF it's given the opportunity to do so. --Why thorough blood tests and a G.I. Effects stool kit are important to effectively battle these kinds of diseases. —Plus, you'll hear the inspiring story of Susan, a patient at Holistic Integration, and why she says that LOVE is what differentiates Holistic Integration from other health care options.   www.TheVoiceOfHealthRadio.com

This episode, in honor of World Ocean Day: Bacteria that may move between high and low pressure areas in the ocean use a particular molecule to protect their cells from being crushed! Download Episode (6.6 MB, 9.5 minutes) Show notes: Microbe of the episode: Rickettsia rickettsii   News item   Takeaways Life in the ocean can have many challenges, depending on the organism and where it lives. Microbes can be found in almost every region, from the warmest to coldest, brightest to darkest, and shallowest to deepest. Sometimes microbes are carried from shallow to deep regions, where the weight of so much water causes immense pressure, which can inhibit cellular structural integrity and function. So life in the deep sea must have ways to deal with this pressure to survive. In this study, bacteria transform a fairly common chemical into a molecule that cushions and protects their cellular structures from the effects of high pressure, allowing them to survive lower down than they would otherwise.   Journal Paper: Qin Q-L, Wang Z-B, Su H-N, Chen X-L, Miao J, Wang X-J, Li C-Y, Zhang X-Y, Li P-Y, Wang M, Fang J, Lidbury I, Zhang W, Zhang X-H, Yang G-P, Chen Y, Zhang Y-Z. 2021. Oxidation of trimethylamine to trimethylamine N -oxide facilitates high hydrostatic pressure tolerance in a generalist bacterial lineage. Sci Adv 7:eabf9941. Other interesting stories: Engineering microbes to produce petroleum product precursor isoprene   Email questions or comments to bacteriofiles at gmail dot com. Thanks for listening! Subscribe: Apple Podcasts, Google Podcasts, Android, or RSS. Support the show at Patreon, or check out the show at Twitter or Facebook.

Kris Newby discusses her Lyme history, her extensive research into tick-borne diseases in the USA and where we find ourselves today in this new pandemic world.

This episode covers the 1928 Nobel Prize in Physiology or Medicine, which was awarded to Charles Jules Henri Nicolle. The Nobel Assembly at the Karolinska Institute chose to give Nicolle the award “for his work on typhus”. Topics include some history of typhus epidemics, the work Nicolle did to show lice transmit typhus, and the unusual biology of Rickettsia prowazekii, the bacterium that causes typhus.

Board Certified in Family Medicine, Dr. Kelley was among the first physicians to become Board Certified in Integrative Medicine. She has studied the causes, effects, and treatments of Lyme Disease extensively, and lectures nationally on this and other topics.  Dr. Kelley graduated from The Ohio State University College of Medicine and completed her residency in Family Medicine at St. Joseph Hospital in Chicago.  She is a ten-year member of the Institute of Functional Medicine (IFM), a Director on the board of The International Lyme and Associated Disease Society (ILADS), and is a Founding Member of the Academy of Integrative Health and Medicine (AIHM).  Dr. Kelley is on the faculty at the Feinberg School of Medicine at Northwestern University.   Prior to founding Case Integrative Health, Dr. Kelley practiced medicine at WholeHealth Chicago, Michigan Avenue Immediate Care, and St. Joseph Hospital. In the United States, some ticks carry pathogens that can cause human disease, including: Anaplasmosis is transmitted to humans by tick bites primarily from the blacklegged tick (Ixodes scapularis) in the northeastern and upper midwestern U.S. and the western blacklegged tick (Ixodes pacificus) along the Pacific coast. Babesiosis is caused by microscopic parasites that infect red blood cells. Most human cases of babesiosis in the U.S. are caused by Babesia microti. Babesia microti is transmitted by the blacklegged tick (Ixodes scapularis) and is found primarily in the northeast and upper midwest. Borrelia mayonii infection has recently been described as a cause of illness in the upper midwestern United States. It has been found in blacklegged ticks (Ixodes scapularis) in Minnesota and Wisconsin. Borrelia mayonii is a new species and is the only species besides B. burgdorferi known to cause Lyme disease in North America. Borrelia miyamotoi infection has recently been described as a cause of illness in the U.S. It is transmitted by the blacklegged tick (Ixodes scapularis) and has a range similar to that of Lyme disease. Bourbon virus infection has been identified in a limited number patients in the Midwest and southern United States. At this time, we do not know if the virus might be found in other areas of the United States. Colorado tick fever is caused by a virus transmitted by the Rocky Mountain wood tick (Dermacentor andersoni). It occurs in the the Rocky Mountain states at elevations of 4,000 to 10,500 feet. Ehrlichiosis is transmitted to humans by the lone star tick (Ambylomma americanum), found primarily in the southcentral and eastern U.S. Heartland virus cases have been identified in the Midwestern and southern United States. Studies suggest that Lone Star ticks can transmit the virus. It is unknown if the virus may be found in other areas of the U.S. Lyme disease is transmitted by the blacklegged tick (Ixodes scapularis) in the northeastern U.S. and upper midwestern U.S. and the western blacklegged tick (Ixodes pacificus) along the Pacific coast. Powassan disease is transmitted by the blacklegged tick (Ixodes scapularis) and the groundhog tick (Ixodes cookei). Cases have been reported primarily from northeastern states and the Great Lakes region. Rickettsia parkeri rickettsiosis is transmitted to humans by the Gulf Coast tick (Amblyomma maculatum). Rocky Mountain spotted fever (RMSF) is transmitted by the American dog tick (Dermacentor variabilis), Rocky Mountain wood tick (Dermacentor andersoni), and the brown dog tick (Rhipicephalus sangunineus) in the U.S. The brown dog tick and other tick species are associated with RMSF in Central and South America. STARI (Southern tick-associated rash illness) is transmitted via bites from the lone star tick (Ambylomma americanum), found in the southeastern and eastern U.S. Tickborne relapsing fever (TBRF) is transmitted to humans through the bite of infected soft ticks. TBRF has been reported in 15 states: Arizona, California, Colorado, Idaho, Kansas, Montana, Nevada, New Mexico, Ohio, Oklahoma, Oregon, Texas, Utah, Washington, and Wyoming and is associated with sleeping in rustic cabins and vacation homes. Tularemia is transmitted to humans by the dog tick (Dermacentor variabilis), the wood tick (Dermacentor andersoni), and the lone star tick (Amblyomma americanum). Tularemia occurs throughout the U.S. 364D rickettsiosis (Rickettsia phillipi, proposed) is transmitted to humans by the Pacific Coast tick (Dermacentor occidentalis ticks). This is a new disease that has been found in California. (credits to the CDC for these links) https://www.caseintegrativehealth.com/

I've received reports of large migrations of whiteflies recently in the landscape, from Dallas, Austin and even east Texas regions. It's not uncommon to see large clouds of whiteflies when cotton is 'defoliated' in preparation for harvest; however, whiteflies often need some time to get used to their new plant host (acclimation). Changes in endosymbionts, bacteria found inside the insect that commonly have a mutualistic positive relationship with the insect, are a potential explanation for host shift acclimation. For fun, we also talk about the diabolical ironclad beetle and it's incredibly resilient properties that make engineers interested enough to study. Some references: Asplen, M. K., N. Bano, C. M. Brady, N. Desneux, K. R. Hopper, C. Malouines, K. M. Oliver, J. A. White, and G. E. Heimpel. 2014. Specialisation of bacterial endosymbionts that protect aphids from parasitoids. Ecol. Entomol. 39: 736–739. Hu, F.-Y., and C.-W. Tsai. 2020. Nutritional relationship between Bemisia tabaci and its primary endosymbiont, Portiera aleyrodidarum, during host plant acclimation. Insects. 11: 1–13. Liu, X. D., and H. F. Guo. 2019. Importance of endosymbionts Wolbachia and Rickettsia in insect resistance development. Curr. Opin. Insect Sci. 33: 84–90. Kanakala, S., and M. Ghanim. 2019. Global genetic diversity and geographical distribution of Bemisia tabaci and its bacterial endosymbionts. PLoS One. 14. Weinert, L. A., E. V. Araujo-Jnr, M. Z. Ahmed, and J. J. Welch. 2015. The incidence of bacterial endosymbionts in terrestrial arthropods. Proc. R. Soc. B Biol. Sci. 282: 3–8. Vorburger, C. 2018. Symbiont-conferred resistance to parasitoids in aphids – Challenges for biological control. Biol. Control. 116: 17–26. 

Rickettsia characteristics include parasitic behaviors but they are not worms or protozoa. Rather, they are bacteria and are therefore prokaryotes. The rickettsia family consists of obligatory intracellular bacteria that are transmitted by arthropod vectors. In other words, they need to be inside living cells to stay alive.  Dr. Walker explains to listeners How rickettsia diseases interact with the immune system in a variety of ways, Why their lack of motility outside of living cells makes rickettsia treatment challenging, and How the typhus group of rickettsia has affected history and how Dr. Walker hopes to develop a vaccine. David H. Walker, MD, is a professor in the Department of Pathology and is the Carmage and Martha Walls Distinguished University Chair in Tropical Diseases and Executive Director of the University of Texas MB Center for Biodefense and Emerging Infectious Disease.  He describes various rickettsia causes and symptoms, from the Orientia tsutsugamushi bacteria transmitted by chiggers to others transmitted by lice and ticks.  He explains the means by which scientists determined their inability to live outside of cells and how they are able to observe their invasion and infection with light microscopy.  Their pathogenic effect is widespread, and Dr. Walker describes their effects on World War II and the Vietnam War through the lice vector and typhus spread. Rickettsia symptoms and attacks on the immune system vary greatly and he describes several examples in the two main groups of typhus and spotted fever rickettsia. For example, Rocky Mountain spotted fever bacteria are secreted from the saliva of the tick when it bites. The bacteria is then taken into the skin through phagocytic cells, spreads to the lymphatic cells, and drains into the blood stream and infects the endothelium cells all over the body.  Dr. Walker has worked with rickettsia for 47 years and his particular focus now is on vaccine research and effective rickettsia treatment. For more, see his web page at the University of Texas Medical Branch, utmb.edu/pathology/faculty-directory/david-h-walker-md, and search his name in research systems for publications. Available on Apple Podcasts: apple.co/2Os0myK

Juan Pablo Alvarez Máynez shares his story of overcoming Lyme Disease and achieving terrific health, well-being, and fulfillment. For complete show notes, visit http://youcuredwhat.com/podcast/juanpablo[1:50] In March 2017, at age 30, Juan suffered a tick bite while mountain biking. [3:35] In the first six weeks, Juan saw six different doctors and got many differing diagnoses. At the time he was suffering from chronic fatigue, muscle pain, and mental confusion. [4:50] Juan talked to people who had Lyme Disease or knew people with Lyme. They recommended that he go to the United States (Juan lives in Mexico) to see an allopathic doctor in California. [6:10] Juan was diagnosed with Lyme and confections (Rickettsia and Babesia). He was told it would take four years to heal, with antibiotics being the key to treatment. [7:35] Juan started out on nine different medications. Two or three weeks into this treatment he was suffering from many side effects from all the medications (vomiting, diarrhea, feeling awful); this was a low point for him and he was victimizing himself. [10:00] Lyme Disease is an autoimmune disease. He describes how autoimmune diseases lead to the body attacking itself. [10:55] Lyme Disease is often confused with one or more other autoimmune diseases. It mimics other diseases, making it difficult to diagnose and treat. [13:50] Juan had a wake-up call in his life. [15:50] Juan started putting together a plan to support the medicine. He thought the medicine wouldn’t heal him 100%; his body would have to become stronger too. [16:50] Juan came across a VICE documentary on Wim Hof which described the Wim Hof Method which has potential for helping with autoimmune conditions. [18:50] Wim Hof had found peace and inner strength through a specific breathing practice and through going out into the cold in nature. [19:35] The Wim Hof Method consists of deep breathing, of cold exposure training, and of mindset and commitment. The mind/body connection is very important to the Wim Hof Method. [20:20] Research at Radboud University showed the power of the Wim Hof Method. Initially it showed Wim’s ability to control his autonomic nervous system; this turned out to be repeatable by everyone who used Wim Hof’s method (deep breathing, cold exposure, mindset and commitment). [23:10] Wim Hof found that humans have the ability to regulate their immune reactions and their autonomic nervous systems. [25:50] Wim Hof’s method involves breathwork, cold exposure, meditation, mindset, and commitment. [27:35] After hearing about Wim Hof, Juan thought it could be helpful for his autoimmune condition. He bought a 10-week course on the Wim Hof Method. [28:20] Juan describes his first ice bath experiment (at the 8-week point of the 10-week course). [29:05] Juan was amazed at how he felt in his first ice bath. [32:00] Juan started adopting the mantra “Lyme can’t stop me” [33:40] In less than ten months (as opposed to the predicted 4 years), Juan tested negative for Rickettsia and Baresia. [35:30] What happened in the first eight weeks of Juan practicing the Wim Hof Method? [36:10] Juan felt better energy-wise and in his joints after his first time doing Wim Hof breathing. [42:50] Juan also practices grounding and eats a no-processed-food Paleo alkaline diet. [43:20] After a year of taking medicines alongside his natural approaches, Juan decided to try a fully natural approach (he was still feeling side effects of the medications). [45:50] Juan decided he was going to go all-out for 15 straight days: grounding himself to the earth, getting sunlight into his eyes, eating a Paleo alkaline diet, and sitting in an ice bath every day. [48:20] Juan’s symptoms (“sensations”) went way down from his 15-day focused healing effort. Also his quickness at recovering from ice baths improved dramatically. [50:55] What are the foods Juan ate as part of his paleo alkaline diet? [53:50] Juan considers that his lifestyle (poor diet, unfulfilling career, less-than-ideal friendships), in the years leading up to the tick bite, weakened his immune system. [55:20] “Nutrition is not only food. It’s air you breathe, it’s water you drink, it’s thoughts you put inside your mind.” [56:20] Juan considers lifestyle and thoughts to be a 50/50 split in importance. [57:50] At Wim Hof Method instructor training, Juan felt a calling (“You’re here to do something else”). [1:01:50] Juan also practices fasting now. [1:02:05] Juan finds that we (humans) have too much comfort now. [1:04:10] Juan advocates for a neo-primitive way of living which is more connected with nature. [1:07:40] Juan breaks down the importance of thoughts. [1:10:05] Juan recommends the documentary Transcendence. [1:13:05] Juan describes doing the pose “The Shelf” (similar to a one-arm plank). Visualization helped him accomplish the pose for the first time, after a great deal of practice. [1:16:50] Juan has taken up mountain climbing, even in the cold. [1:18:05] Juan tells the story of his journey from being a successful management consultant at an e-commerce company to becoming a full time Wim Hof Method instructor to help others heal and attain wellness. “It’s not that I don’t like this job, but it doesn’t fulfill me.” [1:24:20] You can find workshops taught by Juan at wimhofmethod.com. Juan is based in Mexico City; he goes to Phoenix and LA fairly often. Also, you can find Juan on Instagram at http://instagram.com/ElSrDeLosHielos [1:26:55] Does Juan consider himself cured? [1:31:40] Now that Juan has improved his health, what’s one thing Juan enjoys doing that he couldn’t do before? [1:34:10] Juan now eats just once per day.

Gram indeterminate - Rickettsia rickettsii

Gram indeterminate - Rickettsia prowazekii

Gram indeterminate - Rickettsia overview

Today we'll talk about a few bacterial causes of fever and rashes.  High-yield, board-relevant information and two board-style practice questions. --- Send in a voice message: https://anchor.fm/bradleysmicroboardreview/message Support this podcast: https://anchor.fm/bradleysmicroboardreview/support

Transmitida pelo carrapato-estrela infectado pela bactéria Rickettsia rickettsii, a febre maculosa se não tratada adequadamente, pode evoluir para quadros graves e levar a pessoa à morte. No Brasil, a maior parte dos casos de febre maculosa ocorre na região sudeste. A doença é transmitida pelo carrapato-estrela, que geralmente é encontrado em capivaras e cavalos. Não há vacina contra a doença, portanto, quem vai para áreas de pasto e grande vegetação deve usar botas e blusas de manga comprida. Outra dica importante é usar roupas claras, pois elas ajudam a identificar o carrapato mais facilmente. Veja também: Febre maculosa | Entrevista

Vincent, Michele, and Michael travel to San Diego to reminisce with Elio about his career, his work in microbiology, and his love for microbes and mushrooms. VIDEO VERSION AVAILABLE: https://www.youtube.com/watch?v=Menlo1YvPko Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email.Get the entire ASM Podcast Network via our Microbeworld app. Become a patronof TWiM. Links for this episode Elio’s profile Elio’s memoirs Elio’s first paper, 1952 (J Bact) In the Company of Mushrooms Small Things Considered TWiM Listener survey Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv  

The TWiM team presents an extracellular bacterium associated with Paramecium, and induction of antiviral immunity by a bacteriophage that prevents bacterial clearance. Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a Patron of TWiM! Bacteria on the outside of paramecia (ISME) Phage trigger antiviral immunity (Science) Image credit Letters read on TWiM 198 Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv

In this very first episode of Infested, we covered unique aspects of flea biology such as solenophagy, high strength legs and jumping capabilities through resilin protein, the benefits of having a laterally compressed body, as well as speciation through genal and pronotal combs. We covered the flea life cycle starting from the egg through to adult emergence including how pupae can survive dormant for years and will rapidly emerge with new host signs. One of the diseases that we discussed was plague, specifically Bubonic plague. Bubonic plague is caused by the transmission of Yersinia pestis bacteria into a vertebrate host through an infected flea bite. The bacteria are regurgitated into the host as the flea tries to take a blood meal while the bacteria forms a thick blockage in its upper digestive tract. We discussed some of the symptoms of plague as well as the historical implications of plague as it has consistently shaped history. Plague is still around today, including endemic levels in the Southwestern United States in enzootic cycles with small mammals like prairie dogs and squirrels. The second disease we dove into was murine typhus also known as flea-borne typhus. Murine typhus is caused by Rickettsia typhii and has many symptoms to other diseases which can make it easy to misdiagnose. We highlighted the current epidemic of murine typhus in California as well as how specific groups are targeted with blame for the epidemic. We talked about vector-borne disease can perpetuate inequality and societal discrimination: a theme that is central to this podcast!   Below is our source material for further reading and exploration! We’ve broken it up into books, peer-reviewed journal articles, and media sources for easy searching.   Thank you for listening! Want to stay in the loop with us on social media? Instagram: @infestedpodcast Twitter: @infestedpodcast // Lindsay’s Twitter:  @Baxter.Lindsay Email: Infestedpodcast@gmail.com   This podcast is produced and edited by Lindsay Baxter and Bailey Willett. Their views and opinions are theirs and do not reflect the institution for which they are employed.   Books Gottfried, R. S. 1983. The black death. Natural and human disaster in medieval europe. The Free Press, New York, N.Y.   Peer Reviewed Sources   Achtman, M., Zurth, K., Morelli, G., Torrea, G., Guiyoule, A., & Carniel, E. (1999). Yersinia pestis, the cause of plague, is a recently emerged clone of Yersinia pseudotuberculosis. Proceedings of the National Academy of Sciences, 96(24), 14043–14048. https://doi.org/10.1073/pnas.96.24.14043 Azad, A. F. (1990). Epidemiology of Murine Typhus. Annual Review of Entomology, 35(1), 553–570. https://doi.org/10.1146/annurev.en.35.010190.003005 Basra, G., Berman, M. A., & Blanton, L. S. (2012). Murine Typhus: An Important Consideration for the Nonspecific Febrile Illness. Case Reports in Medicine, 2012. https://doi.org/10.1155/2012/134601 Burroughs, A. L. (1947). Sylvatic plague studies. The vector efficiency of nine species of fleas compared with Xenopsylla cheopis. Epidemiology & Infection, 45(3), 371–396. https://doi.org/10.1017/S0022172400014042 Chain, P. S. G., Carniel, E., Larimer, F. W., Lamerdin, J., Stoutland, P. O., Regala, W. M., … Garcia, E. (2004). Insights into the evolution of Yersinia pestis through whole-genome comparison with Yersinia pseudotuberculosis. Proceedings of the National Academy of Sciences, 101(38), 13826–13831. https://doi.org/10.1073/pnas.0404012101 Civen, R., & Ngo, V. (2008). Murine Typhus: An Unrecognized Suburban Vectorborne Disease. Clinical Infectious Diseases, 46(6), 913–918. https://doi.org/10.1086/527443 Galimand, M., Guiyoule, A., Gerbaud, G., Rasoamanana, B., Chanteau, S., Carniel, E., & Courvalin, P. (1997). Multidrug Resistance in Yersinia pestis Mediated by a Transferable Plasmid. New England Journal of Medicine, 337(10), 677–681. https://doi.org/10.1056/NEJM199709043371004 Gage, K. L., & Kosoy, M. Y. (2005). NATURAL HISTORY OF PLAGUE: Perspectives from More than a Century of Research. Annual Review of Entomology, 50(1), 505–528. https://doi.org/10.1146/annurev.ento.50.071803.130337 Hardy, A. (1988). Urban famine or urban crisis? Typhus in the Victorian city. Medical History, 32(04), 401–425. https://doi.org/10.1017/S0025727300048523 Peniche Lara, G., Dzul-Rosado, K. R., Zavala Velázquez, J. E., & Zavala-Castro, J. (n.d.). Murine Typhus. Colombia Médica : CM, 43(2), 175–180. Perry and Fetherston - 1997 - Yersinia pestis--etiologic agent of plague..pdf. (n.d.). Retrieved from https://cmr.asm.org/content/cmr/10/1/35.full.pdf Perry, R. D., & Fetherston, J. D. (1997). Yersinia pestis--etiologic agent of plague. Clinical Microbiology Reviews, 10(1), 35–66. https://doi.org/10.1128/CMR.10.1.35 Randremanana, R., Andrianaivoarimanana, V., Nikolay, B., Ramasindrazana, B., Paireau, J., Bosch, Q. A. ten, … Rajerison, M. (2019). Epidemiological characteristics of an urban plague epidemic in Madagascar, August–November, 2017: an outbreak report. The Lancet Infectious Diseases, 0(0). https://doi.org/10.1016/S1473-3099(18)30730-8 Reeves, W. K., Murray, K. O., Meyer, T. E., Bull, L. M., Pascua, R. F., Holmes, K. C., & Loftis, A. D. (2008). Serological evidence of typhus group rickettsia in a homeless population in Houston, Texas. Journal of Vector Ecology, 33(1), 205–207. https://doi.org/10.3376/1081-1710(2008)33[205:SEOTGR]2.0.CO;2 Ritzmann, I. (1998). [The Black Death as a cause of the massacres of Jews: a myth of medical history?]. Medizin, Gesellschaft, Und Geschichte: Jahrbuch Des Instituts Fur Geschichte Der Medizin Der Robert Bosch Stiftung, 17, 101–130. Schriefer, M. E., Sacci, J. B., Taylor, J. P., Higgins, J. A., & Azad, A. F. (1994). Murine Typhus: Updated Roles of Multiple Urban Components and a Second Typhuslike Rickettsia. Journal of Medical Entomology, 31(5), 681–685. https://doi.org/10.1093/jmedent/31.5.681 Typhus reaches “epidemic levels” in parts of Los Angeles. (n.d.). Retrieved February 21, 2019, from https://www.nbcnews.com/news/us-news/typhus-reaches-epidemic-levels-parts-los-angeles-area-n917271 Walker, D. H., & Fishbein, D. B. (1991). Epidemiology of rickettsial diseases. European Journal of Epidemiology, 7(3), 237–245. https://doi.org/10.1007/BF00145672 Whiteford, S. F., Taylor, J. P., & Dumler, J. S. (2001). Clinical, Laboratory, and Epidemiologic Features of Murine Typhus in 97 Texas Children. Archives of Pediatrics & Adolescent Medicine, 155(3), 396–400. https://doi.org/10.1001/archpedi.155.3.396   Popular Media Sources   CNN, J. H. (n.d.). Flea-borne typhus spreads across LA area. Retrieved March 26, 2019, from CNN website: https://www.cnn.com/2018/10/08/health/typhus-epidemic-los-angeles-bn/index.html Department of Public Health - Acute Communicable Disease Control. (n.d.). Retrieved March 26, 2019, from http://www.publichealth.lacounty.gov/acd/vectortyphus.htm Filip, I. (2014, April 11). Avoiding the Black Plague Today. Retrieved April 3, 2019, from The Atlantic website: https://www.theatlantic.com/health/archive/2014/04/avoiding-black-plague-today/360475/ Plague | Plague | CDC. (2018, November 27). Retrieved April 3, 2019, from https://www.cdc.gov/plague/index.html Outbreak of “medieval” typhus in Los Angeles spreads from homeless communities. (2019, February 4). [MovingImage]. Retrieved February 21, 2019, from http://video.foxnews.com/v/5998442627001/ Jones, J. (2012, February 15). Brush with the Black Death: how artists painted through the plague. The Guardian. Retrieved from https://www.theguardian.com/artanddesign/jonathanjonesblog/2012/feb/15/brush-black-death-artists-plague

What do lice, flying squirrels, and World War I have in common? That weird question is answered by Jake Lininger from the 2019 Hiram College Genetics course as he introduces us to the cause of epidemic typhus - the pathogenic bacterium Rickettsia prowazekii.

Why You Should Listen: In this episode, you will learn about EliSpot testing and the various testing options available through ArminLabs in Germany. About My Guest: My guest for this episode is Dr. Armin Schwarzbach. Armin Schwarzbach, MD, PhD is a medical doctor and a specialist in laboratory medicine from the laboratory ArminLabs in Augsburg, Germany. Dr. Schwarzbach began by studying biochemistry at Hoechst AG in Frankfurt, Germany and pharmacy at the University of Mainz in Germany in 1984. In 1985 he studied medicine for 6 years at the University of Mainz and finished his MD in 1991. Dr. Schwarzbach developed the worldwide first Radioimmunoassay (RIA) for human Gastric Inhibitory Polypeptide from 1986 – 1991, getting his PhD in 1992. He is member of the Swiss Association for tick-borne diseases, the German Association of Clinical Chemistry and Laboratory Medicine, and the German Society for Medical Laboratory Specialists. He is an Advisory Board member of AONM London, England, and Board member of German Borreliosis Society, and Member and former Board Member of the International Lyme and Associated Diseases Society (ILADS) and has served as an expert on advisory committees on Lyme Disease in England, Australia, Canada, Ireland, France, and Germany. Dr. Schwarzbach is the founder and CEO of ArminLabs in Augsburg, Germany and has specialized in diagnostic tests and treatment options for patients with tick-borne diseases for over 20 years. Key Takeaways: - What is an EliSpot? - What organisms can be tested for using EliSpot technology? - How specific is the EliSpot in testing for Borrelia, Bartonella, Babesia, and other organisms? - Does the state of the immune system matter when considering EliSpot results? - Which infections are the most persistent? - Can the EliSpot be used to track progress or success of treatment? - What is Yersinia and where might it be encountered? - Can EliSpot testing be used in newborns and infants? - What role do viruses such as EBV, CMV, Coxsackie, and others play in chronic illness? - Can Mast Cell Activation Syndrome be triggered by viruses? - Why are Mycoplasma and Chlamydia so important to explore? - Why is IgA testing a promising new direction in laboratory medicine? - Is CD57 helpful clinically? - What microbes are more commonly associated with specific medical conditions? - How common are Rickettsial organisms? - What is "Post Lyme Syndrome"? Is it real? Connect With My Guest: http://arminlabs.com Interview Date: February 27, 2019 Additional Information: To learn more, visit http://BetterHealthGuy.com. Disclaimer: The content of this show is for informational purposes only and is not intended to diagnose, treat, or cure any illness or medical condition. Nothing in today's discussion is meant to serve as medical advice or as information to facilitate self-treatment. As always, please discuss any potential health-related decisions with your own personal medical authority.

Chronic Fatigue Syndrome is now officially known as Myalgic Encephalomyelitis (ME/CFS). The CDC believes this is a vastly under-diagnosed condition. In this episode, you'll learn: --Why Chronic Fatigue Syndrome was a diagnosis that did not get much respect. And why the name change was encouraged by government agencies in 2015. --How the Centers for Disease Control believes that 90-95% of cases are not being diagnosed or treated properly. --That even children can be affected by ME/CFS, though it is more common in women, minorities, and those between the ages of 33 and 50. --Why a person's "phase angle" (or electromagnetic charge around the cells) can indicate the condition. --How one-fourth of those with ME/CFS are bedridden and unable to function. And how the Social Security department wanted to create more awareness of this disease because it costs between $17 and $24 billion annually. --The symptoms of ME/CFS, including: severe fatigue for at least six months, cognitive impairment, muscle or joint pain, headaches, swelling of lymph nodes, sore throat, and complete exhaustion after any kind of mental or physical work. --The underlying viral infections that can cause ME/CFS, including: Epstein-Barr virus, Lyme Disease, Rickettsia, Retroviruses, Bornaviruses, Fungi and Mycoplasma, Flu viruses, Xenotropic murine leukemia virus-related virus (XMRV), and Cytomegalovirus. --Why The Structure-Function approach used by The Prather Practice is "really the only way of getting success" with this disease process. And why there is really no effective Disease Care approach to ME/CFS. --How Homeopathy stimulates the immune system to combat the underlying viruses that cause ME/CFS. And why those with ME/CFS "do not do well" with pharmaceuticals and antibiotics. --The effectiveness of supplementation, herbals, Chiropractic adjustments, Acupuncture, and therapeutic massage for ME/CFS patients. And the importance of blood analysis every three months for these patients. www.TheVoiceOfHealthRadio.com

Dr. Didier Raoult considers himself a “microbe fisher”, always “fishing” to discover new microbes. He says that in order to fish successfully, you need to first create the correct fishing pole (tools), and then fish in places where no one else is fishing. Dr. Raoult is the Director of the Mediterranean Infection Foundation at the Aix-Marseille University, France, and he has “caught” a number of unique microbes over the course of his career, including giant viruses. He’s also “caught” a number of bacteria responsible for various diseases, including the causative agent of Whipple’s disease, and he even has two bacteria named after him. Dr. Raoult talks about what is special about giant viruses, how he found the bacterium that causes Whipple’s disease, the challenges of trying to get uncultured bacteria like Rickettsia to grow in the lab, and how he would be sailing if he weren’t a microbiologist. microTalk recorded this discussion with Dr. Raoult at the American Society for Microbiology Microbe 2018 meeting in Atlanta, Georgia, and we're pleased to be joined by ASM’s Meet the Microbiologist host Julie Wolf. The microCase for listeners to solve is about Laguna Beech, a yoga instructor whose young son comes down with a life-threatening illness while she’s at a yoga ashram in India. Participants: Karl Klose, Ph.D. (UTSA) Didier Raoult, M.D., Ph.D. (Aix-Marseille University) Janakiram Seshu, Ph.D. (UTSA) Jesus Romo, Ph.D. (UTSA) Julie Wolf, Ph.D. (ASM) Mylea Echazarreta (UTSA)

In this episode, Dr’s J and Santhosh go all in on Rickettsia and some of its diseases. Along the way they discuss micro machines, disney songs, black measles, the dangers of losing funding, victorian tick tindr, the many faces of rickettsia, its typical features, findings, and presentation, treatment and more. SO sit back and prepare to rock out with your spots out as we continue our ongoing plagues series!SOurces1)https://www.niaid.nih.gov/about/rocky-mountain-history2)http://www.merckmanuals.com/professional/infectious-diseases/rickettsiae-and-related-organisms/overview-of-rickettsial-and-related-infections3)https://www.cdc.gov/mmwr/volumes/65/rr/rr6502a1.htm4)https://wwwnc.cdc.gov/travel/yellowbook/2018/infectious-diseases-related-to-travel/rickettsial-spotted-and-typhus-fevers-and-related-infections-including-anaplasmosis-and-ehrlichiosisContact Us!Twitter: @doctorjcomedy @toshyfro Facebook: facebook.com/travelmedicinepodcastSquarespace: travelmedicinepodcast.squarespace.comPatreon: https://www.patreon.com/travelmedicinepodcastGoogle Voice: (872) 216-1586Find and Review Us on itunes, stitcher, spokeo, google play, or wherever podcasts are availableitunes: https://itunes.apple.com/us/podcast/episodes-travel-medicine-podcast/id914407095stitcher: http://www.stitcher.com/podcast/travel-medicine-podcast?refid=stprGoogle Play: https://play.google.com/music/listen#/ps/Iebqxcseb4s6pu5sjyljwgqsbuyYouTube: https://www.youtube.com/playlist?list=PLr4fcpX27x2vcJT_zJq6qiBy0pK8WiEXe

The TWiP professors solve the case of the Woman With Intracellular Ring Forms, and explore the role of Coxiella and Rickettsia endosymbionts in acquisition of Babesia by ticks. Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin Become a patron of TWiP. Links for this episode: Endosymbionts and Babesia in ticks (Front Microbiol) Q fever with Robert Heintzen (TWiM Special) Hero: Percy Garnham Image credit Letters read on TWiP 157 Case Study for TWiP 157 Back to Thailand. Housewife, complaint has multiple red bumps on body, intense itching, worse at night. On head, legs, upper chest. Also does not feel well, feverish, muscle aches, difficulty breathing. Moved into abandoned residence, symptoms began a few days later. Many coconut husks around. Thatched roof. Husband and children developed similar symptoms. No med/surg history, no allergies. No meds. Unused mattresses, rat nests around. No toxic habits, no travel. No pets. On exam: not febrile, not toxic, increased heart, breathing comfortably. Has multiple red papules, central punctum. Labs unremarkable. Diff: unremarkable 6% eosinophils. Skin scraping from lesion on chest done. Send your case diagnosis, questions and comments to twip@microbe.tv Music by Ronald Jenkees

How you feel is how your immune system feels. Dr. Prather says that 80-90% of patients have a compromised immune system when he reviews their blood analysis. In this episode, you'll learn: --How all of us have cancer cells in our body, but cancer develops when our immune system fails. --The different parts of our immune system, and the two main components of the immune system (that Dr. Prather classifies as "snipers" and "bombers"). --Why a child's immune system is completely different from an adult's immune system. --The autoimmune diseases that wrongly attack our body, such as: Cron's Disease, Ulcerative Colitis, Rheumatoid Arthritis, Lupus, and Multiple Sclerosis. --How the Structure-Function Health Care analysis of blood work is different than the Disease Care analysis. And why patients must choose between a Disease Care approach that further suppresses the immune system or a Structure-Function Health Care approach that rebuilds the immune system. --Why Dr. Prather says Homeopathics are a "magic weapon" for the immune system and that doctors are doing a "disservice" for patients if they are trying to treat the immune system without Homeopathics. Plus, why pharmaceuticals should be used sparingly, while Homeopathics should be used generously. --The "extremely dramatic" results ("better than any pharmaceutical") Dr. Prather has seen with Homeopathics for patients that have longstanding infections such as Epstein-Barr virus, Rickettsia, and Lyme Disease. --The critical role of Vitamin D for the immune system and the connection between cholesterol and Vitamin D. And why those on cholesterol-lowering drugs are more susceptible to a weakened immune system. --How Zinc deficiency (which most people have) is a major problem for the immune system. --Why chicken soup really does help boost the immune system. www.TheVoiceOfHealthRadio.com

Nie dajmy się kleszczom! W ciągu ostatnich 30 lat zachorowalność na choroby odkleszczowe wzrosła! Kleszcze (różne gatunki) są przenosicielami dziesiątków drobnoustrojów, bakterii, wirusów, grzyboów, pasożytów itd. Mogą zakazić swojego żywiciela krętkami boreliozy (borelioza z Lyme = krętkowica kleszczowa), pałeczką tularemii Francissella tularensis, riketsją Coxiella burnetii (gorączka Q), Rickettsia canada (gorączka plamista Gór Skalistych), Rickettsia conori (gorączka śródziemnomorka – guzkowa, południowoafrykańska, dur kleszczowy, gorączka kleszczowa), Rickettsia australis (dur kleszczowy Queensland), Rickettsia akari (ospa riketsjowa) i wirusem kleszczowego zapalenia mózgu. Sezon żerowania kleszy w Polsce wydłużył się średnio o 1,5 miesiąca! Szczyt zachorowań przypada zwykle na miesiące kwiecień - lipiec. Każda samica składa kilkaset larw. Powinniśmy mieć świadomość, że już nawet najmniejsze larwy mogą zaatakować ludzi, jeśli nie ma innego wyjścia. "Natomiast przykre jest to, że nadal nie ma niestety jednolitych standardów leczenia i o nie walczymy" - mówi dr Wojciech Ozimek.

In Cambodia, the number of reported malaria cases, as well as case fatality rates, continue to decrease since the implementation of large scale malaria programs in the country 10 years ago. However, with the introduction and wide distribution of rapid diagnostic tests (RDTs) for malaria, it also turned out that in many of the clinically suspected malaria cases, no malaria parasites could be detected. As a first step towards developing an algorithm for malaria-RDT negative fever management at peripheral health posts, a cross-sectional, prospective, observational study was designed to investigate the causes of acute malaria-negative febrile illness in rural areas of Cambodia. From January 2008 to December 2010, 1475 study subjects were recruited in three different sites throughout the country. Among the study subjects, 1193 were febrile out-patients and 282 were non-febrile individuals who have been recruited as a control group. A battery of test was run on the samples in the central laboratory in Phnom Penh. In 73.2% of the 1193 febrile outpatient samples, at least one pathogen was identified. In 26.8% of these samples the etiology of the fever remained unknown. Most frequent pathogens detected by molecular diagnostics were P. vivax (26.4%), P. falciparum (20.7%), Leptospira (9.5%), Dengue Virus (5.4%), Influenza Virus A (5.9%), O. tsutsugamushi (3.7%), Influenza Virus B (1.8%), Rickettsia (0.2%) and bacteria from blood culture (Salmonella spp., E. coli, S. pneumoniae, E. cloacae) (0.8%). Conclusions: Malaria is still amongst the principal causes of undifferentiated fever in this setting, even though RDTs did not prove sufficient to diagnose cases of low parasitemia and infections with P. vivax. RDT-negative fever cases should be tested for malaria using microscopy or ideally PCR. If malaria is ruled out, diagnostic tools are needed to distinguish between either viral or bacterial etiology of the fever. Leptospirosis and rickettsial diseases showed to play an important role and are easily treatable with the right antibiotics. However, more research and better diagnstic tools are needed to understand and map the incidence of these diseases in Cambodia.

Als ein vom Menschen stark beeinflusstes und freizeitlich genutztes Ökosystem sind städtische Grünflächen in Hinblick auf zeckenübertragene Krankheiten von besonderem wissenschaftlichem Interesse. Zu diesem Zweck wurden Zecken monatlich über zwei Jahre in insgesamt neun verschiedenen Parks in fünf bayerischen Städten mit der Flaggmethode gesammelt und die Zeckendichte(Adulte und Nymphen/100m²) ermittelt. Neun Standorte wurden 2009 mittels spezifischer konventioneller und real-time PCRs auf die Anwesenheit von DNA von Babesia spp., A. phagocytophilum, Rickettsia spp.und Bartonella spp. untersucht sowie fünf ausgewählte Standorte zusätzlich auf Babesia spp. und A. phagocytophilum in 2010. Speziesdifferenzierungen wurden mittels Sequenzanalyse und Abgleich der amplifizierten PCR-Produkte mit der GenBank vorgenommen. Es wurden insgesamt 13.403 I. ricinus sowie jeweils eine I. frontalis und I. hexagonus gefangen. Die Zeckendichte variierte zwischen 15 - 53 Zecken/100m² in 2009 bzw 15 - 35 Zecken/100m² in 2010 abhängig vom untersuchten Standort. Eine Stichprobe von 6.593 Zecken (5.569 für A. phagocytophilum) wurde untersucht mit folgenden Ergebnissen: Babesia spp.(2009: 0,4% mit einem Larvenpool (Lp) à 2 Larven; 2010: 0,5-0,7% mit einem Lp à 5 Larven); A. phagocytophilum (2009: 9,5%; 2010: 6,6%); Rickettsia spp. (2009: 6,4-7,7% mit 76 Larven in 16 Lps). Sequenzanalysen ergaben die Anwesenheit von Babesia sp. EU1 (n= 25), B. divergens (n= 1), B. divergens/capreoli (n= 1), B. gibsoni-like (n= 1), R. helvetica (n= 272), R. monacensis strain IrR/Munich (n= 12) und R. monacensis (n= 1). Die Anwesenheit von Bartonella spp konnte nicht nachgewiesen werden. Coinfektionen wurden in 0,7% aller untersuchten Zecken in 2009 festgestellt. Eine weiterführende Analyse positiver A. phagocytophilum-Proben bezüglich des 16S rRNA-Gens ergab sechs verschiedene Sequenzvarianten, von welchen schon zwei mit Erkrankungsfällen im Menschen assoziiert wurden. Prävalenzschwankungen zwischen Jahren und Standorten sowie ein außergewöhnliches Speziesauftreten von Babesia spp. zeigen, dass das Vorkommen von zeckenübertragenen Pathogenen von einer Vielzahl biotischen und abiotischen Faktoren abhängig sein kann und das Habitat „Stadtpark“ dabei eine besondere Stellung einnimmt.

Background: The aims of this study were to evaluate the host-tick-pathogen interface of Babesia spp. and Anaplasma phagocytophilum in restored areas in both questing and host-attached Ixodes ricinus and Dermacentor reticulatus and their small mammalian hosts. Methods: Questing ticks were collected from 5 sites within the city of Leipzig, Germany, in 2009. Small mammals were trapped at 3 of the 5 sites during 2010 and 2011. DNA extracts of questing and host-attached I. ricinus and D. reticulatus and of several tissue types of small mammals (the majority bank voles and yellow-necked mice), were investigated by PCR followed by sequencing for the occurrence of DNA of Babesia spp. and by real-time PCR for A. phagocytophilum. A selected number of samples positive for A. phagocytophilum were further investigated for variants of the partial 16S rRNA gene. Co-infection with Rickettsia spp. in the questing ticks was additionally investigated. Results: 4.1% of questing I. ricinus ticks, but no D. reticulatus, were positive for Babesia sp. and 8.7% of I. ricinus for A. phagocytophilum. Sequencing revealed B. microti, B. capreoli and Babesia spp. EU1 in Leipzig and sequence analysis of the partial 16S RNA gene of A. phagocytophilum revealed variants either rarely reported in human cases or associated with cervid hosts. The statistical analysis revealed significantly less ticks infected with A. phagocytophilum in a city park in Leipzig as compared to the other sampling sites. A. phagocytophilum-DNA was detected in 2 bank voles, DNA of B. microti in 1 striped field-mouse and of Babesia sp. EU1 in the skin tissue of a mole. Co-infections were detected. Conclusion: Our results show the involvement of small mammals in the natural endemic cycles of tick-borne pathogens. A more thorough understanding of the interactions of ticks, pathogens and hosts is the essential basis for effective preventive control measures.

Sat, 12 Feb 2011 12:00:00 +0100 https://edoc.ub.uni-muenchen.de/12917/ https://edoc.ub.uni-muenchen.de/12917/1/Schex_Susanne_Yvonne.pdf Schex, Susanne Yvonne ddc:590, ddc:500, Tierärztliche Fakult

Background: Only limited information is available about the occurrence of ticks and tick-borne pathogens in public parks, which are areas strongly influenced by human beings. For this reason, Ixodes ricinus were collected in public parks of different Bavarian cities in a 2-year survey (2009 and 2010) and screened for DNA of Babesia spp., Rickettsia spp. and Bartonella spp. by PCR. Species identification was performed by sequence analysis and alignment with existing sequences in GenBank. Additionally, coinfections with Anaplasma phagocytophilum were investigated. Results: The following prevalences were detected: Babesia spp.: 0.4% (n = 17, including one pool of two larvae) in 2009 and 0.5 to 0.7% (n = 11, including one pool of five larvae) in 2010; Rickettsia spp.: 6.4 to 7.7% (n = 285, including 16 pools of 76 larvae) in 2009. DNA of Bartonella spp. in I. ricinus in Bavarian public parks could not be identified. Sequence analysis revealed the following species: Babesia sp. EU1 (n = 25), B. divergens (n = 1), B. divergens/capreoli (n = 1), B. gibsoni-like (n = 1), R. helvetica (n = 272), R. monacensis IrR/Munich (n = 12) and unspecified R. monacensis (n = 1). The majority of coinfections were R. helvetica with A. phagocytophilum (n = 27), but coinfections between Babesia spp. and A. phagocytophilum, or Babesia spp. and R. helvetica were also detected. Conclusions: I. ricinus ticks in urban areas of Germany harbor several tick-borne pathogens and coinfections were also observed. Public parks are of particularly great interest regarding the epidemiology of tick-borne pathogens, because of differences in both the prevalence of pathogens in ticks as well as a varying species arrangement when compared to woodland areas. The record of DNA of a Babesia gibsoni-like pathogen detected in I. ricinus suggests that I. ricinus may harbor and transmit more Babesia spp. than previously known. Because of their high recreational value for human beings, urban green areas are likely to remain in the research focus on public health issues.

In recent years, Anaplasma phagocytophilum and Rickettsia spp. have been detected in Ixodes ricinus in Germany and a focal distribution has been suggested for A. phagocytophilum. In the present study the prevalence of A. phagocytophilum and spotted fever group (SFG) rickettsiae was investigated in I. ricinus. DNA-extracts were taken from 2,862 unfed I. ricinus ticks (adults and nymphs) from eight sites in Munich, sampled over a five-month period. Single samples from three comparative sites outside of Munich were also included. A real-time PCR targeting the msp2 gene of A. phagocytophilum was used for screening and a nested PCR targeting the 16S rRNA gene for sequencing of 30% of positives. Screening for Rickettsia spp. was performed with a PCR targeting the citrate synthase gene (gltA), followed by PCRs detecting the ompA gene for all gltA positives, and the ompB and 16S rRNA genes for clarifying results of some samples. The overall prevalence was 2.90% (95% CI 2.27 to 3.48%) for A. phagocytophilum and 5.28% (95% CI 4.31 to 6.17%) for SFG rickettsiae. Only 0.31% of the ticks investigated were coinfected. Statistical analysis revealed that prevalence of A. phagocytophilum in ticks from city parks in Munich was significantly higher than in ticks from natural forest, whereas the prevalence of Rickettsia spp. was the opposite. For both, the prevalence in adults was significantly higher than in nymphs. Although wide ranges of prevalence were observed monthly, the variations were not significant along the observational period. Sequence analysis of 16S rRNA PCR products (n=31) revealed 100% homology to Ehrlichia sp. “Frankonia 2”, only one differed in one nucleotide position. All differed in one nucleotide position from the HGA agent detected in human patients. All rickettsial PCR products were also sequenced. All gltA sequences of R. helvetica (n=138) were 100% identical to each other and differed in one nucleotide position from the prototype sequence. Two different R. monacensis strains (n=13) were detected, which differed in up to 4 nucleotide positions in gltA, ompA and ompB. Further rickettsial strains (n=3) most probably belonging to rickettsial endosymbionts were also found. These results show, by molecular methods, a wide distribution of A. phagocytophilum and SFG rickettsiae in I. ricinus ticks in Southern Germany. SFG rickettsiae which are thought to be involved in human disease (R. helvetica and R. monacensis) had a significantly higher prevalence in natural forest areas. Prevalence of A. phagocytophilum was significantly higher in city parks; the genetic strain has not yet been associated with human infection.