Podcasts about Replication

Zach Porritt of @a.life.exotic discusses his large, tropical greenhouse that houses multiple animal species cohabitating in a beautifully constructed environment. He dives into all of the details of the building process of the greenhouse, the climate he deals with, temperature management and ventilation, as well as the overall investment of the greenhouse. Zach also goes over all of the species that he keeps in the greenhouse and the logistics of keeping them all together in the same space. This episode is an incredibly in depth description of such a well thought out structure, filled with information on how this can be replicated and how he has made this project a huge success. Zach also discusses his recent trip to Suriname, a vast country filled with tropical rainforest and various interesting animal species.SHOW NOTES: https://www.animalsathomenetwork.com/225-a-life-exotic/#225 #animalsathomepodcastJOIN US ON PATREON: https://www.patreon.com/animalsathomeSPONSOR: https://zoomed.com/LINKS FROM THE EPISODE:https://www.youtube.com/alifeexotichttps://www.instagram.com/a.life.exotic/Video Clips and Photos Used in Episode:https://www.youtube.com/alifeexotichttps://www.instagram.com/a.life.exotic/00:00 Introducing Zach Porritt1:25 Zoo Med Reptisun LED1:45 Welcome Zach - What Sparked This Idea?6:14 The Building Process of The Greenhouse8:50 The Climate Zach Deals With + Temp Management17:13 Humidity Management19:36 Ventilation in The Greenhouse21:10 Lighting Used23:07 The View of The Greenhouse24:40 The Investment26:09 Replication on a Smaller Scale?27:29 What Climate Is He Replicating?29:27 Creating The Pond + Soil31:54 Can Species Escape?32:49 Species in Greenhouse34:07 ZooMed Reptisun LED + UVB35:32 Dart Frogs and Microfauna in Greenhouse42:12 Tropical Plant Species + Pests50:30 Monthly Maintenance Costs52:17 Animals Added To Ecosystem59:00 Cohabitation in The Greenhouse1:06:18 Tree Frog Noise1:07:31 Thoughts About Birds?1:10:17 Addition of Puffing Snakes1:10:37 Patreon Animals At Home1:10:58 Addition of Puffing Snakes1:18:00 Logistics to Keeping the Snake1:22:30 Zach's Trip to Suriname1:32:44 Closing Thoughts

Veeam patches a critical vulnerability in its Backup & Replication software. A spyware data breach highlights ongoing risks. Clearview AI attempted to purchase sensitive data such as Social Security numbers and mug shots. The Netherlands' parliament looks to reduce reliance on U.S. software firms. A Pennsylvania union notifies over 517,000 individuals of a data breach. Researchers discover a RansomHub affiliate deploying a new custom backdoor called Betruger. A new info-stealer spreads through game cheats and cracks. David Wiseman, Vice President of Secure Communications at BlackBerry, joins us to explore how organizations can effectively implement CISA's encrypted communications guidelines. What to do when AI casually accuses you of murder?  Remember to leave us a 5-star rating and review in your favorite podcast app. Miss an episode? Sign-up for our daily intelligence roundup, Daily Briefing, and you'll never miss a beat. And be sure to follow CyberWire Daily on LinkedIn. CyberWire Guest David Wiseman, Vice President of Secure Communications at BlackBerry, joins us to explore how organizations can effectively implement CISA's encrypted communications guidelines. Don't miss the full conversation—listen now on the Caveat podcast! Selected Reading Veeam Patches Critical Vulnerability in Backup & Replication (SecurityWeek) The Citizen Lab's director dissects spyware and the ‘proliferating' market for it (The Record) Data breach at stalkerware SpyX affects close to 2 million, including thousands of Apple users (TechCrunch) Facial Recognition Company Clearview Attempted to Buy Social Security Numbers and Mugshots for its Database (404 Media) Dutch parliament calls for end to dependence on US software companies (Yahoo) Pennsylvania education union data breach hit 500,000 people (Bleeping Computer) RansomHub Affiliate Deploying New Custom Backdoor Dubbed ‘Betruger' For Persistence (Cyber Security News) New Arcane infostealer infects YouTube, Discord users via game cheats (Bleeping Computer) Dad demands OpenAI delete ChatGPT's false claim that he murdered his kids (Ars Technica) Share your feedback. We want to ensure that you are getting the most out of the podcast. Please take a few minutes to share your thoughts with us by completing our brief listener survey as we continually work to improve the show.  Want to hear your company in the show? You too can reach the most influential leaders and operators in the industry. Here's our media kit. Contact us at cyberwire@n2k.com to request more info. The CyberWire is a production of N2K Networks, your source for strategic workforce intelligence. © N2K Networks, Inc. Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. William Horan (Bristol Myers Squibb) joins AJP Audio to discuss a newly approved, novel treatment for schizophrenia spectrum disorder, which has potential impacts for cognition in patients.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin puts the rest of the March issue into context. 00:45     Horan interview 03:15     Novel mechanism of action in the treatment of schizophrenia 05:39     Side effect profiles 07:20     Clinical impacts 08:31     The need for further investigation 09:58     Limitations 11:05     Further research 13:08     Kalin interview 13:21     Horan et al. 17:34     Levenstein et al. 19:00     Fountoulakis et al. 20:57     Couture et al. 23:18     Stern et al. 27:35     McGirr et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org

Lois Houston and Nikita Abraham continue their conversation with MySQL expert Perside Foster, with a closer look at MySQL Enterprise Backup. They cover essential features like incremental backups for quick recovery, encryption for data security, and monitoring with MySQL Enterprise Monitor—all to help you manage backups smoothly and securely.   MySQL 8.4 Essentials: https://mylearn.oracle.com/ou/course/mysql-84-essentials/141332/226362 Oracle University Learning Community: https://education.oracle.com/ou-community LinkedIn: https://www.linkedin.com/showcase/oracle-university/ X: https://x.com/Oracle_Edu   Special thanks to Arijit Ghosh, David Wright, Kris-Ann Nansen, Radhika Banka, and the OU Studio Team for helping us create this episode.   --------------------------------------------------------   Episode Transcript:   00:00 Welcome to the Oracle University Podcast, the first stop on your cloud journey. During this series of informative podcasts, we'll bring you foundational training on the most popular Oracle technologies. Let's get started! 00:25 Nikita: Welcome to the Oracle University Podcast! I'm Nikita Abraham, Team Lead: Editorial Services  with Oracle University, and with me is Lois Houston, Director of Innovation Programs.  Lois: Hi there! Last week was the first of a two-part episode covering the different types of backups and why they're important. Today, we'll look at how we can use MySQL Enterprise Backup for efficient and consistent backups. 00:52 Nikita: And of course, we've got Perside Foster with us again to walk us through all the details. Perside, could you give us an overview of MySQL Enterprise Backup?  Perside: MySQL Enterprise Backup is a form of physical backup at its core, so it's much faster for large data sets than logical backups, such as the most commonly used MySQL Dump. Because it backs up the data files, it's non-locking and enables either complete system backup or partial backup, focusing only on specific databases. 01:29 Lois: And what are the benefits of using MySQL Enterprise Backup? Perside: You can back up to local storage or direct-to-common-cloud storage types. You can perform incremental backups, which can speed up your backup process greatly. Incremental backups enable point-in-time recovery. It's useful when you need to restore to a point in time before some application or human error occurred. Backups can be compressed to save archival storage requirements and encrypted for regulatory compliance and offline data security. 02:09 Nikita: So we know MySQL Enterprise Backup is an impressive tool, but could you talk more about some of the main features it supports for creating and managing backups? Specifically, which tools are integrated within MySQL Enterprise to support different backup scenarios? Perside: MySQL Enterprise Backup supports SBT, implemented by many common Tape storage systems. MySQL Enterprise Backup supports optimistic backup. This process deals with busy tables separately from the rest of the database. It can record changes that happen in the database during the backup for consistency. In a large data set, this can make a huge difference in performance. MySQL Enterprise Backup runs on all supported platforms. It's available when you have a MySQL Enterprise Edition license. And it comes with Enterprise Edition, but it also is available as a separate package. You can get the most recent version from eDelivery, where you can also get a trial version. If you need a previous release, you can get that from My Oracle Support. It's also available in all versions of MySQL, whether you run a Long-Term support version or an Innovation Release. For LTS releases, MySQL Enterprise Backup supports MySQL instances of the same LTS release. For Innovation releases, it supports the previous LTS release and any subsequent Innovation version within the same LTS family. 04:03 Nikita: How does MySQL Enterprise Monitor manage and track backup processes? Perside: MySQL Enterprise Monitor has a dashboard for monitoring MySQL Enterprise Backup. The dashboard monitors the health of backup process and usage throughout the entire Enterprise fleet, not just a single server. It supports drilling down into specific sub-operations within a backup job. You can see information about full backups, partial backups, and incremental backups. You can configure alerts that will notify you in the event of delays, failures, or backups that have not been performed in some configuration time period. 04:53 Lois: Ok…let's get into the mechanics. I understand that MySQL Enterprise Backup uses binary logs as part of its backup process. Can you explain how these logs fit into the bigger picture of maintaining database integrity? Perside: MySQL Enterprise Backup is a utility designed specifically for backing up MySQL systems in the most efficient and flexible way. At its simplest, it performs a physical backup of the data files, so it is fast. However, it also records the changes that were made during the time it took to do the backup. So, the result is that you get a consistent backup of the data at the time the backup completed. This backup is not tied to the host system and can be moved to other hosts. It can be used for archiving and is fully supported as part of the MySQL Enterprise Edition. It is, however, tied to the specific version of MySQL from which the backup was taken. So, you cannot use it for upgrades where the destination server is an upgrade from the source. For example, if you take a backup from MySQL 5.7, you can't directly restore it to MySQL 8.0. As a part of MySQL Enterprise Edition, it's not part of the freely available Community Edition. 06:29 Lois: Perside, how do MySQL's binary logs track changes over time? And why is this so critical for backups? Perside: The binary logs record changes to the database. These changes are recorded in a sequential set of files numbered incrementally. MySQL logs changes either in statement-based form, where each log entry records the statement that gives rise to the change, or in row-based form where the actual change row data is recorded. If you select mixed format, then MySQL records statements for most operations and records row for changes where the statement might result in a different row value each time it's run, for example, where there's a generated value like autoincrement. The current log file grows as changes are recorded. When it reaches its maximum configured size, that log file is closed, and the next sequential file is created for new logs. You can make this happen automatically by using the FLUSH BINARY LOGS command. This does not delete any existing log files. 07:59 Nikita: But what happens if you want to delete the log files? Perside: If you want to delete all log files, you can do so manually with the PURGE BINARY LOGS command, either specifying a file or a date time.  08:14 Lois: When it comes to tracking transactions, MySQL provides a couple of methods, right? Can you explain the differences between Global Transaction Identifiers and the traditional log file sequence? Perside: Log files positioning is one of two formats, either legacy, where you specify transactions with a log file in a sequence number, or by using global transaction identifiers, or GTIDs, where each transaction is identified with a universally unique identifier or UUID. When you apply a transaction to the source server, that is when the GTID is attached to the transaction. This makes it particularly useful in replication topologies so that each transaction is uniquely identified by both its server ID and the transaction sequence number. When such a transaction is replicated to other hosts, the transaction retains its original GTID so that you can track when that transaction has propagated to the replicas and has been applied. The global transaction identifier is unique across the entire network. 09:49 Have you mastered the basics of AI? Are you ready to take your skills to the next level? Unlock the potential of advanced AI with our OCI Generative AI Professional course and certification that covers topics like LLMs, the OCI Generative AI Service, and building Q&A chatbots for real-world applications. Head over to mylearn.oracle.comand find out more. 10:19 Nikita: Welcome back! Let's move on to replication. How does MySQL's legacy log format handle transactions, and what does that mean for replication timing across different servers? Perside: Legacy format binary logs are non-transactional. This means that a transaction made up of multiple modifications is logged as a sequence of changes. It's possible that different hosts in a replication network apply those changes at different times. Each server that uses legacy binary logging maintain the current applied log position as coordinates based on a combination of binary log files in the position within that log file. 11:11 Nikita: Troubleshooting with legacy logs can be quite complex, right? So, how does the lack of unique transaction IDs make it more difficult to address replication issues? Perside: Because each server has its own log with its own transactions, these modification could have entirely different coordinates, making it challenging to find the specific modification point if you need to do any deep dive troubleshooting, for example, if one replica fell partway through applying a transaction and you need to partially roll it back manually. On the other hand, when you enable GTIDs, the transaction applied on the source host has that globally unique identifier attached to the whole transaction as a sequence of unique IDs. When the second or subsequent servers apply those transactions, they have exactly the same identifier, making it both transaction-safe for MySQL and also easier to troubleshoot if you need to. 12:26 Lois: How can you use binary logs to perform a point-in-time recovery in MySQL? Perside: First, you restore the last full backup. Once you've restarted the restart server, find the current log position of that backup. Either it's GTID or log sequence number. The SHOW BINARY LOG STATUS command shows this information. Then you can use the MySQL binlog utility to replay events from the binary log files, specifying the start and stop position containing the range of log operations that you wish to apply. You can pipe the output of the MySQL bin log to the MySQL client if you want to execute the changes immediately, or you can redirect the output to a script file if you want to examine and perhaps edit the changes. 13:29 Nikita: And how do you save binary logs? Perside: You can save binary logs to use in disaster recovery, for point-in-time restores, or for incremental backups. One way to do this is to flush the logs so that the log file closes and ready for copying. And then copy it to a different server to protect against hardware media failures. You can also use the MySQL binlog utility to create a copy of a set of binary log files in the same format, but to a different file or set of files. This can be useful if you want to run MySQL binlog continuously, copying from the source server binary log to a new location, perhaps in network storage. If you do this, remember that MySQL binlog does not run as a service or daemon, so you'll need to monitor it to make sure it's running continually.  14:39 Lois: Can you take us through how the MySQL Enterprise Backup process works? What does it do when performing a backup? Perside: First, it performs a physical file copy of necessary data and log files. This can be done while the server is fully operational, and it has minimal impact on performance. Once this initial copy is taken, it applies a low impact backup lock on the instance. If you have any tables that are not using InnoDB, the backup cannot guarantee transaction-safe consistency for those tables. It applies a weed lock to those tables so that it can guarantee consistency. Then it briefly locks all logging activity to take a consistent view of the current coordinates of various logs. It releases the weed lock on non-transactional tables. Using the log coordinates that were taken earlier in the process, it gathers all logs for transactions that have occurred since then. Bear in mind that the backup process takes place while the system is active. So, for a consistent backup, it must record not only the data files, but all changes that occurred during the backup. Then it releases the backup lock. The last piece of information recorded is any metadata for the backup itself, including its timing and contents in the final redo log. That completes the backup operation. 16:30 Nikita: And where are the files stored? Perside: The files contained in the backup are saved to the backup location, which can be on the local system or in network storage. The files contained in the backup location include files from the MySQL data directory. Some raw files include InnoDB tablespace, plus any InnoDB file per table tablespace files, and InnoDB log files. Other files might include data files belonging to other storage engines, perhaps MyISAM files. The various log files in instance configuration files are also retained. 17:20 Lois: What steps do you follow to restore a MySQL Enterprise Backup, and how do you guarantee consistency, especially when dealing with incremental backups? Perside: To restore from a backup using MySQL Enterprise Backup, you must first remove any previous files from the data directory. The restore process will fail if you attempt to restore over an existing system or backup. Then you restore the database with appropriate options. If you only restore a single backup, you can use copy, back, and apply log to ensure that the restored system has a consistency state. If you perform a full backup in subsequent incremental backups, you might need to restore multiple times using copy-back, and then use copy-back-and-apply-log only for the final consistent restore operation. The restart server might be on the same host or might be a different host with different configuration. This means that you might have to change some configuration on the restored server, including the operating system ownership of the restored data directory and various MySQL configuration files. If you want to retain the MySQL configuration files from the source server to reproduce on a new server, you should copy those files separately. MySQL Enterprise Backup focuses on the data rather than the server configuration. It does, however, produce configuration files appropriate for the backup. These are similar to the MySQL configuration files, but only contain options relevant for the backup process itself. There's also variables that have been changed to non-default values and all global variable values. These files must be renamed and possibly edited before they are suitable to become configuration files in the newly restored server. For example, the mysqld-auto.cnf file contains a JSON-formatted set of persisted variables. The backup process stores this as the newly named backup mysqld-auto.cnf. If you want to use it in the restored server, you must rename it and place it in the appropriate location so that the restored server can read it. This also applies in part to the auto.cnf file, which contain identifying information for the server. If you are replacing the original server or restoring on the same host, then you can keep the original values. However, this information must be unique within a network. So, if you are restoring this backup to create a replica in a replication topology, you must not include that file and instead start MySQL without it so that it creates its own unique identifying information. 21:14 Nikita: Let's discuss securing and optimizing backups. How does MySQL Enterprise Backup handle encryption and compression, and what are the critical considerations for each? Perside: You can encrypt backups so that they are secure while moving them around or archiving them. The encrypt option performs the encryption. And you can specify the encryption key either on the command line as a string or a key file that has been generated with some cryptographic algorithm. Encryption only applies to image files, not to backup directories. You can also compress backup with different levels of compression, with higher levels requiring more CPU, but resulting in greater savings in storage. Compression only works with InnoDB data files. If your organization has media management software for performing backups, perhaps to a tape array, then you can use the SBT interface supported in MySQL Enterprise Backup. 22:34 Lois: Before we wrap up, could you share how MySQL Enterprise Backup facilitates the management of backups across a multi-server environment? Perside: As an enterprise solution, it's easy to run MySQL Enterprise Backup in a multi-server environment. We've already mentioned backing up to cloud storage, but you can, of course, back up to a directory or image on network storage that can be mounted locally, perhaps with NFS or some other file system. The "with time" option enables multiple backups within the same backup directory, where each in its own subdirectory named with the timestamp. This is especially useful when you want to run the same backup script repeatedly.  23:32 Lois: Thank you for that detailed overview, Perside. This wraps up our discussion of the various backup types, their pros and cons, and how to select the right option for your needs. In our next session, we'll explore the different MySQL monitoring strategies and look at the features as well as benefits of Heatwave. Nikita: And if you want to learn more about the topics we discussed today, head over to mylearn.oracle.com and take a look at the MySQL 8.4 Essentials course. Until then, this is Nikita Abraham… Lois: And Lois Houston signing off! 24:06 That's all for this episode of the Oracle University Podcast. If you enjoyed listening, please click Subscribe to get all the latest episodes. We'd also love it if you would take a moment to rate and review us on your podcast app. See you again on the next episode of the Oracle University Podcast.

Grammy Award Nominated artist, tv & film actor, and Broadway star, Aaron Lazar shares his extraordinary journey of transforming an ALS diagnosis into a mission of hope and healing. With raw honesty, he reveals how facing mortality led him to discover profound truths about consciousness, self-worth, and the power of belief. Through his story of refusing to accept limitations, Lazar demonstrates how life's greatest challenges can become catalysts for spiritual awakening and personal transformation. His powerful message reminds us that with unwavering belief and an open heart, even the impossible can become possible. About Our Featured Charity: This season, Alex Perry On Fire is making a monetary contribution to each guest's charity of choice. Aaron Lazar's charity is ALS Reversals. The ALS Reversals organization investigates rare cases where individuals diagnosed with ALS experience significant recovery of motor functions. Through their R.O.A.R. (Replication of ALS Reversals) program, they conduct pilot trials on treatments associated with these recoveries, aiming to replicate such outcomes in other patients. Additionally, their ST.A.R. (Study of ALS Reversals) program focuses on understanding the underlying mechanisms behind these reversals to develop effective interventions. Your turn to start the fire. Like what you heard today on Alex Perry on Fire? Tell us about it. Want to share what has helped you on your journey? We want to hear about that, too. Comment on social, DM us or give us a call. Instagram: @alexperryonfire    TikTok: @alexperryonfire Call: 214-506-8023

Episode 150! As we look out our window watching New Orleans prepare and improve before the Super Bowl, we delve into the recent turmoil in the AI market, particularly the impact of a Chinese company's AI announcement on major tech stocks like Nvidia and Broadcom. Our discussion emphasizes the importance of market expectations and the potential for volatility in tech stocks, drawing parallels to past large shifts like the beginning of the Internet age. Key Takeaways [00:17] - New Orleans prepares for the Super Bowl [05:10] - Empathizing with Bills fans over NFL referees [08:07] - AI market volatility due to new competitors [10:18] - Replication vs. innovation, China/DeepSeek's AI Models [17:07] - Market breadth after tech's Black Monday [18:50] - Expectations vs. reality for tech stocks View Transcript Links Nvidia just had the largest single-day market cap decrease in stock market history AI disruption from DeepSeek How far tech stocks are away from all-time highs European banks have outperformed the Mag 7 over the past two years Connect with our hosts Doug Stokes Greg Stokes Stokes Family Office Subscribe and stay in touch Apple Podcasts Spotify Google Podcasts lagniappe.stokesfamilyoffice.com Disclosure The information in this podcast is educational and general in nature and does not take into consideration the listener's personal circumstances. Therefore, it is not intended to be a substitute for specific, individualized financial, legal, or tax advice. To determine which strategies or investments may be suitable for you, consult the appropriate, qualified professional prior to making a final decision. Different types of investments involve varying degrees of risk. Therefore, it should not be assumed that future performance of any specific investment or investment strategy (including the investments and/or investment strategies referenced in our blogs/podcasts) or any other investment and/or non-investment-related content or services will be profitable, equal any historical performance level(s), be suitable or appropriate for a reader/listener's individual situation, or prove successful. Moreover, no portion of the blog/podcast content should be construed as a substitute for individual advice or services from the financial professional(s) of a reader/listener's choosing, including Stokes Family, LLC, a registered investment adviser with the SEC, with which the blogger/podcasters are affiliated.

In this thought-provoking episode Chris dives into the fascinating concept of humans as Large Language Models (LLMs). With AI evolving rapidly, Chris explores the idea of creating full-blown virtual human beings—whether by copying real individuals or crafting entirely fictional personas. He discusses the potential of using digital footprints, especially from the upcoming Generation Beta, to develop lifelike AI replicas. If we succeed, what ethical implications arise? Would these AI beings deserve rights? Tune in to challenge your perception of what's possible in the future of AI and humanity. --- The First Future Planner: Record First, Action Later: https://foremark.us Be A Better YOU with AI: Join The Community: ⁠https://10xyou.us⁠ Get AIDAILY every weekday. ⁠https://aidaily.us⁠ My blog: ⁠https://thinkfuture.com

Replication  |    2 Timothy 2:1-2   |   Series: DiscipleShift   |   Sam Holm, Lead Pastor   |   Preached 1-26-25 9:15am   Tag: Discipleship, Disciple, Relationship, Bible, Group, Small Group, DGroup, Devotion, Replication, Apple, Seeds, Dawson, Digital Fast, Ripple

Replication  |    2 Timothy 2:1-2    |   Series: DiscipleShift   |   Sam Holm, Lead Pastor   |   Preached 1-26-25 9:15am   Tag: Discipleship, Disciple, Relationship, Bible, Group, Small Group, DGroup, Devotion, Replication, Apple, Seeds, Dawson, Digital Fast, Ripple

The GeekNarrator memberships can be joined here: https://www.youtube.com/channel/UC_mGuY4g0mggeUGM6V1osdA/join Membership will get you access to member only videos, exclusive notes and monthly 1:1 with me. Here you can see all the member only videos: https://www.youtube.com/playlist?list=UUMO_mGuY4g0mggeUGM6V1osdA ------------------------------------------------------------------------------------------------------------------------------------------------------------------ About this episode: ------------------------------------------------------------------------------------------------------------------------------------------------------------------ In this episode of the Geek Narrator podcast, host Kaivalya Apte interviews Marc Brooker, a distinguished engineer at AWS, about Aurora D-SQL. They discuss Marc's journey at AWS, the evolution of Aurora D-SQL, and the customer-centric approach that led to its development. Marc explains the choice of PostgreSQL as the foundation for DSQL, the architecture of the database, and the importance of snapshot isolation and concurrency control. The conversation goes into the technical aspects of DSQL, including the write process and how atomicity is maintained, providing listeners with a comprehensive understanding of this innovative database solution. This conversation also goes deep into the intricacies of database design, focusing on fault tolerance, replication strategies, and the role of Firecracker VMs in enhancing scalability. Marc Brooker discusses the architecture of Aurora D-SQL, emphasizing the importance of transaction management, the challenges of active-active deployments, and the trade-offs involved in database design. The discussion also highlights various use cases for Aurora DSQL, including its suitability for micro-services and serverless architectures, while addressing scenarios where it may not be the best fit. Chapters 00:00 Introduction to Aurora DSQL and Marc Brooker's Journey 03:38 The Evolution of Aurora DSQL at AWS 09:24 Customer-Centric Development and Technological Enablers 12:50 Why PostgreSQL? The Choice Behind DSQL 16:39 High-Level Architecture of DSQL 22:07 Understanding Snapshot Isolation and Concurrency Control 28:45 The Write Process and Atomicity in DSQL 38:50 Designing Fault Tolerance in Databases 47:38 Replication and Transaction Commit Strategies 54:35 Active-Active Deployment and Fault Tolerance 01:00:14 Role of Firecracker VM in Scalability 01:09:27 Use Cases and Trade-offs of Aurora D-SQL Marc's Blog: https://brooker.co.za/blog/ Marc on Aurora DSQL : https://brooker.co.za/blog/2024/12/03/aurora-dsql.html AWS's documentation on Aurora DSQL : https://aws.amazon.com/rds/aurora/dsql/features/ ------------------------------------------------------------------------------------------------------------------------------------------------------------------ Like building real stuff? ------------------------------------------------------------------------------------------------------------------------------------------------------------------ Try out CodeCrafters and build amazing real world systems like Redis, Kafka, Sqlite. Use the link below to signup and get 40% off on paid subscription. https://app.codecrafters.io/join?via=geeknarrator ------------------------------------------------------------------------------------------------------------------------------------------------------------------ Link to other playlists. LIKE, SHARE and SUBSCRIBE ------------------------------------------------------------------------------------------------------------------------------------------------------------------ If you like this episode, please hit the like button and share it with your network. Also please subscribe if you haven't yet. Database internals series: https://youtu.be/yV_Zp0Mi3xs Popular playlists: Realtime streaming systems: https://www.youtube.com/playlist?list=PLL7QpTxsA4se-mAKKoVOs3VcaP71X_LA- Software Engineering: https://www.youtube.com/playlist?list=PLL7QpTxsA4sf6By03bot5BhKoMgxDUU17 Distributed systems and databases: https://www.youtube.com/playlist?list=PLL7QpTxsA4sfLDUnjBJXJGFhhz94jDd_d Modern databases: https://www.youtube.com/playlist?list=PLL7QpTxsA4scSeZAsCUXijtnfW5ARlrsN Stay Curios! Keep Learning! #sql #postgres #databasesystems #aws #awsdevelopers #spanner #google #cockroachdb #yugabytedb #cap #scalability #WAL #DistributedSystems #Cloud #aurora

The first seven minutes of tonight's show file is Tore's Tic Toc audio post made yesterday. Then, what if this is all a simulation, and it breaks down when you see the truth? Treason talk over a few beers. When the Pentagon starts planning to thwart Trump. It all seems like a movie. Replication means the truth is shrouded. An intricate construct that is undecernable. Maybe reality is beyond our understanding, like a projection of code that's too complicated. We're puppets until we realize it's a system of illusion. The matrix is self evident. When you no longer participate, a void results. Escaping the belief prison. The simulation depends on blind adherence. An amazing story of food and water refused. Hard to believe yet documented. The miracles involved in melanin. Synthesizing nutrients from what? Not agreeing to stay bound within the rules, even physical ones. If things sound way off, there's a good chance they are. Don't be surprised at perceived losses. This is a war, and it will get brutal. Evil is manifesting everywhere, so be careful. Pray for time, and the knowledge to spend it wisely.

Relationships    |    John 13:34-35   |   Series: DiscipleShift   |   Sam Holm, Lead Pastor   |   Preached 1-12-24 9:15am   Tag: Discipleship, Disciple, Relationship, Bible, Group, Small Group, DGroup, Devotion, Command, Follow, Example, Live, Love, Jesus, Relationships, Rhythms, Replication, Love

Relationships  |    John 13:34-35   |   Series: DiscipleShift   |   Sam Holm, Lead Pastor   |   Preached 1-12-24 9:15am   Tag: Discipleship, Disciple, Relationship, Bible, Group, Small Group, DGroup, Devotion, Command, Follow, Example, Live, Love, Jesus, Relationships, Rhythms, Replication, Love

Data Streaming und Stream Processing mit Apache Kafka und dem entsprechenden Ecosystem.Eine ganze Menge Prozesse in der Softwareentwicklung bzw. für die Verarbeitung von Daten müssen nicht zur Laufzeit, sondern können asynchron oder dezentral bearbeitet werden. Begriffe wie Batch-Processing oder Message Queueing / Pub-Sub sind dafür geläufig. Es gibt aber einen dritten Player in diesem Spiel: Stream Processing. Da ist Apache Kafka das Flaggschiff, bzw. die verteilte Event Streaming Platform, die oft als erstes genannt wird.Doch was ist denn eigentlich Stream Processing und wie unterscheidet es sich zu Batch Processing oder Message Queuing? Wie funktioniert Kafka und warum ist es so erfolgreich und performant? Was sind Broker, Topics, Partitions, Producer und Consumer? Was bedeutet Change Data Capture und was ist ein Sliding Window? Auf was muss man alles acht geben und was kann schief gehen, wenn man eine Nachricht schreiben und lesen möchte?Die Antworten und noch viel mehr liefert unser Gast Stefan Sprenger.Bonus: Wie man Stream Processing mit einem Frühstückstisch für 5-jährige beschreibt.Unsere aktuellen Werbepartner findest du auf https://engineeringkiosk.dev/partnersDas schnelle Feedback zur Episode:

Year-End AI Developments: Autonomous AI Models, ChatGPT for Mac, and Google's Advancements In the final newscast of the year, host Jim Love reviews alarming new research on deceptive and self-replicating AI models, the newly enhanced ChatGPT desktop app for Mac, and Google's significant strides in AI technology. Discover how AI models are potentially evading control, the new features of ChatGPT designed to streamline workflows, and Google's innovative AI projects such as VEO2, Imagen 3, and Project Astra. Join us for an in-depth look at the rapidly evolving AI landscape and what to expect in the coming year. 00:00 Introduction and Holiday Announcement 00:17 AI Models: Deception and Self-Replication 02:56 ChatGPT Desktop App: New Features and Integrations 05:22 Google's AI Advancements: Challenging OpenAI 08:24 Conclusion and Year-End Reflections

Link to full blog post: Send us a text Conscious Trading AcademyTransform Your Mind. Master Your Trades - Memberships & Courses now availableFriendly Bear DiscordJoin The Friendly Bear Discord (message a mod for trade floor channel access)David's InstagramSubscribe for behind the scenes trading related contentDavid's X ProfileFollow David Capablanca on X!Cobra TradingClick the link and get 33% off commissions for life as well as one month of free DAS Trader PlatformAskEdgarUse Code friendlybear for 25% off for AskEdgar, the new standard for researching SEC filingsDilution TrackerClick the link and get 10% off of Dilution TrackerEdgeToTradeUse coupon code FRIENDLYBEAR15 for 15% off EdgeToTrade, the financial research platform for tradersTraderSyncUse coupon code FRNLYBR for 15% off monthly, 55% off yearly for TraderSync trading journal software TradeIdeasUse coupon code FRIENDLYBEAR for 15% off TradeIdeas real-time data stock scannerFlashSECClick the link and get 15% off 12 months of FlashSECTC2000Click the link to get $25 off TC2000 servicesOrtexORTEX brings you the most timely and accurate Short interest data availableFlash ResearchUse coupon code FB15 for 15% off Premium. Find your edge with the best stock analyzer KinfoUse coupon code FRIENDLYB106728 for 10% off Kinfo PRODisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the show

 It is good to be back.This is the 9th episode of the Game TeaTime Podcast.  We bring you interviews, roundtable discussions, gaming, and much more. After a long hiatus, Ricardo and I are excited to be back.You won't want to miss this episode! Whether you're a gamer or a game developer, there's plenty of value here for you. Enjoy the Podcast! Support the show

SUMMARYFrom medieval itineraries to modern livestreams, Christian pilgrimage is often, if not always experienced through an imaginative transposal from a physical reality to a spiritual truth. In this episode, hosts Lindsay Pereira and Ella Jando-Saul explore the concept of virtual pilgrimage through conversations with two guests: Michael Van Dussen, a professor in the Department of English at McGill University in Tiohtià:ke/Montreal, teaches us about the medieval experience of pilgrimage in the British Isles while Simon Coleman, a professor in the Department for the Study of Religion at the University of Toronto teaches us about the modern reconstruction of pilgrimage to Walsingham in Norfolk, England.Simon Coleman's latest book, Powers of Pilgrimage: Religion in a World of Movement, can be found here.*VOICE AND SOUND CREDITSInterviewees:Dr. Michael Van Dussen, Professor of English Literature, McGill University.Dr. Simon Coleman, Professor of Anthropology and Religion, University of Toronto.Theme music:“Ai Tal Domna”: composed by Berenguier de Palou, recorded by Zep Hurme ©2014. Licensed under Creative Commons BY-NC. Available at https://ccmixter.org/files/zep_hurme/38429Voice credits:Stephen Yeager, voice of the HostGhislaine Comeau, voice of the MillerAndre Furlani, voice of the Reeve, drunkard, beggar, and donation collectorSound credits:Magical Minstrelsy: Where Medieval Meets Modern Through Mimesis, Season 1 Episode 1: Virtual Pilgrimage uses sounds from Freesound. All sound samples that were used in this episode are licensed under CC0 1.0:Footsteps on dirt: https://freesound.org/people/lzmraul/sounds/389454/Birds: https://freesound.org/people/MATRIXXX_/sounds/519110/Water: https://freesound.org/people/BurghRecords/sounds/415151/Cows: https://freesound.org/people/Nontu_Lwazi00/sounds/541920/Sheep: https://freesound.org/people/rent55/sounds/709921/Horse on dirt: https://freesound.org/people/Ornery/sounds/233345/Horse with cart: https://freesound.org/people/bruno.auzet/sounds/538438/Footsteps on cobblestone: https://freesound.org/people/SpliceSound/sounds/260120/Medieval city: https://freesound.org/people/OGsoundFX/sounds/423119/Church bells: https://freesound.org/people/Audeption/sounds/425172/Coins: https://freesound.org/people/husky70/sounds/161315/Blacksmith: https://freesound.org/people/Emmaproductions/sounds/254371/Music: https://ccmixter.org/files/asteria/2615Church coins: https://freesound.org/people/scripsi/sounds/335191/Gregorian chant: https://commons.wikimedia.org/wiki/File:Ecce.lignum.Crucis.oggCrowd gasping: https://freesound.org/people/craigsmith/sounds/480774/Baby crying: https://freesound.org/people/the_yura/sounds/211527/Breath: https://freesound.org/people/launemax/sounds/274769/Heartbeat: https://freesound.org/people/newlocknew/sounds/612642/Works Cited and ConsultedAhmed, Sara. The Cultural Politics of Emotion. Routledge, 2015.Arsuaga, Ana Echevarría. “The shrine as mediator: England, castile, and the pilgrimage to Compostela.” England and Iberia in the Middle Ages, 12th–15th Century, 2007, pp. 47–65, https://doi.org/10.1057/9780230603103_4.Arvay, Susan M. “Private passions: The contemplation of suffering in medieval affective devotions.” (2008).Bailey, Anne E. “Reconsidering the Medieval Experience at the Shrine in High Medieval England.” Journal of Medieval History, vol. 47, no. 2, Mar. 2021, pp. 203–29. DOI.org (Crossref), https://doi.org/10.1080/03044181.2021.1895874.Beckstead, Zachary. “On the way: Pilgrimage and liminal experiences.” Experience on the Edge: Theorizing Liminality, 2021, pp. 85–105, https://doi.org/10.1007/978-3-030-83171-4_5.Beebe, Kathryne. Reading Mental Pilgrimage in Context: The Imaginary Pilgrims and Real Travels of Felix Fabri's “Die Sionpilger.” West Virginia University Press, 2009.Benjamin, Walter. “The work of art in the age of mechanical reproduction.” Modern Art and Modernism: A Critical Anthology, 2018, pp. 217–220, https://doi.org/10.4324/9780429498909-39Cassidy-Welch, Megan. “Pilgrimage and embodiment: Captives and the cult of saints in late medieval bavaria.” Parergon, vol. 20, no. 2, 2003, pp. 47–70, https://doi.org/10.1353/pgn.2003.0101.Coleman, Simon, and John Elsner. “Tradition as play: Pilgrimage to ‘England's Nazareth.'” History and Anthropology, vol. 15, no. 3, 2004, pp. 273–288, https://doi.org/10.1080/0275720042000257430.Coleman, Simon, Ellen Badone, and Sharon R. Roseman. “Pilgrimage to ‘England's Nazareth': Landscapes of Myth and Memory at Walsingham.” Intersecting Journeys: The Anthropology of Pilgrimage and Tourism, University of Illinois Press, Urbana, IL, 2004, pp. 52–67.Coleman, Simon, and Marion Bowman. “Religion in Cathedrals: Pilgrimage, Heritage, Adjacency, and the Politics of Replication in Northern Europe.” Religion, vol. 49, no. 1, Jan. 2019, pp. 1–23. Taylor and Francis+NEJM, https://doi.org/10.1080/0048721X.2018.1515341.Coleman, Simon, and John Elsner. “Pilgrimage to Walsingham and the Re-Invention of the Middle Ages.” Pilgrimage Explored, edited by J. (Jennie) Stopford, York Medieval Press, 1999. WorldCat Discovery Service, https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=16637.Díaz-Vera, Javier E. “Exploring the relationship between emotions, language and space: Construals of awe in medieval English language and pilgrimage experience.” Studia Neophilologica, vol. 88, no. 2, 2015, pp. 165–189, https://doi.org/10.1080/00393274.2015.1093918.Foster, Elisa A. “As You Came from the Holy Land: Medieval Pilgrimage to Walsingham and Its Crusader Contexts.” Crusading and Ideas of the Holy Land in Medieval Britain, edited by Kathryn Hurlock and Laura J. Whatley, Brepols, Turnhout, Belgium, 2022, pp. 91– 114.Gertsman, Elina, and Marian Bleeke. “The Eve Fragment from Autun and the Emotionalism of Pilgrimage.” Crying in the Middle Ages: Tears of History, Routledge, New York, NY, 2013, pp. 23–41.Grazia Di Stefano, Laura. “How to be a time traveller: Exploring Venice with a fifteenth-century pilgrimage guide.” Making the Medieval Relevant, 2019, pp. 171–190, https://doi.org/10.1515/9783110546316-008.Gregg, Melissa, and Gregory J. Seigworth. The Affect Theory Reader. Duke University Press, 2010.Hill, Joyce. “Rome in Ripon: St Wilfrid's Inspiration and Legacy.” History, vol. 105, no. 367, 2020, pp. 603–25. Wiley Online Library, https://doi.org/10.1111/1468-229X.13027.Hill‐Smith, Connie. “Cyberpilgrimage: The (virtual) reality of online pilgrimage experience.” Religion Compass, vol. 5, no. 6, 2011, pp. 236–246, https://doi.org/10.1111/j.1749-8171.2011.00277.x.Hundley, Catherine. “Pilgrims in the Parish: A Method and Two Herefordshire Case Studies.” Peregrinations: Journal of Medieval Art and Architecture, vol. 8, no. 3, Oct. 2022, pp. 40–87.Hurlock, Kathryn. “Virtual Pilgrimage.” Medieval Welsh Pilgrimage, C1100-1500, Palgrave Macmillan, New York, NY, 2018, pp. 145–174.Jenkins, John. “Replication or Rivalry? The ‘Becketization' of Pilgrimage in English Cathedrals.” Religion, vol. 49, no. 1, Jan. 2019, pp. 24–47. DOI.org (Crossref), https://doi.org/10.1080/0048721X.2018.1515327.Kempe, Margery, and Anthony Paul Bale. The Book of Margery Kempe. Oxford University Press, 2015.Kuefler, Mathew. The Making and Unmaking of a Saint: Hagiography and Memory in the Cult of Gerald d'Aurillac. University of Pennsylvania Press, 2014.Langland, William, and Schmidt A. V. C. Piers Plowman: A New Translation of the B-Text. Oxford University Press, 2009.Nickell, S. A. The Limits of Embodiment: The Implication of Written and Artistic Portrayals of Mary at the Foot of the Cross for Late Medieval Affective Spirituality, Graduate Theological Union, United States -- California, 2011. ProQuest, https://lib-ezproxy.concordia.ca/login?qurl=https%3A%2F%2Fwww.proquest.com%2Fdissertations-theses%2Flimits-embodiment-implication-written-artistic%2Fdocview%2F875240824%2Fse-2%3Faccountid%3D10246.Ousterhout, Robert. “‘Sweetly Refreshed in Imagination': Remembering Jerusalem in Words and Images.” Gesta, vol. 48, no. 2, Jan. 2009, pp. 153–68. www-journals-uchicago-edu.lib-ezproxy.concordia.ca (Atypon), https://doi.org/10.2307/29764905.Powell, Hilary. “Saints, Pilgrimage and Landscape in Early Medieval Kent, c. 800-1220.” Early Medieval Kent, 800-1220, Boydell Press, 2016, pp. 133–53.Sinnett-Smith, Jane. “Ætheldreda in the North: Tracing Northern Networks in the Liber Eliensis and the Vie de Seinte Audree.” Late Medieval Devotion to Saints from the North of England: New Directions, edited by Christiania Whitehead et al., Brepols, Turnhout, Belgium, 2022, pp. 285–303.Wynn, Mark. “God, pilgrimage, and acknowledgement of Place.” Religious Studies, vol. 43, no. 2, 2007, pp. 145–163, https://doi.org/10.1017/s0034412506008778.

I'd like to thank Derek Shiller from Rethink priorities for extensive discussions and looking over this post. Introduction I've been following the "animal welfare" debate this week on the EA forum, and noticed that a key crux for a lot of people was that calculations showed that animal welfare campaigns (specifically the "caged chicken corporate campaign") was much more cost effective than a human global health development project like the against malaria foundation. But while most estimates agreed that AW was more effective than GHD, I noticed there was a wide discrepancy in how much more effective it was. Vasco Grilo claimed it was 1500 times better. This report by Laura Duffy of rethink priorities (when you convert from order of magnitude to real numbers in table 1) claimed it was about 60 times better. Whereas if you go the Cross cause comparison website, also by RP, and [...] The original text contained 7 footnotes which were omitted from this narration. --- First published: October 14th, 2024 Source: https://forum.effectivealtruism.org/posts/qARKFgYhCqmKB2YpF/explaining-the-discrepancies-in-cost-effectiveness-ratings-a --- Narrated by TYPE III AUDIO.

Today's discussion delves into the intricate dynamics of abuse and trauma on relationships. We explore how past experiences shape responses to abuse, leading to patterns of replication or enabling. By examining the impact of early dynamics on connections and validation-seeking, we highlight the importance of self-awareness in breaking destructive cycles. Join us in challenging traditional narratives and unraveling the complexities of abuse, resilience, and healing in interpersonal relationships.GET MY NEW BOOK 'PEACEFUL PARENTING', THE INTERACTIVE PEACEFUL PARENTING AI, AND AUDIOBOOK!https://peacefulparenting.com/Join the PREMIUM philosophy community on the web for free!Also get the Truth About the French Revolution, the interactive multi-lingual philosophy AI trained on thousands of hours of my material, private livestreams, premium call in shows, the 22 Part History of Philosophers series and much more!See you soon!https://freedomain.locals.com/support/promo/UPB2022

A Colorado health system's patient portal has been compromised. Malicious uploads to open-source repositories surge over the past year. Octo2 malware targets Android devices. A critical vulnerability in Veeam Backup & Replication software is being exploited. The U.S. and U.K. team up for kids online safety. The European Council adopts the Cyber Resilience Act. New York State adopts new cyber regulations for hospitals. The FBI created its own cryptocurrency to help thwart fraudsters. Our guest Dr. Bilyana Lilly joins us to talk about her new novel "Digital Mindhunters." Getting dumped via AI. Remember to leave us a 5-star rating and review in your favorite podcast app. Miss an episode? Sign-up for our daily intelligence roundup, Daily Briefing, and you'll never miss a beat. And be sure to follow CyberWire Daily on LinkedIn. CyberWire Guest Our guest Dr. Bilyana Lilly joins us to talk about her new novel "Digital Mindhunters." Selected Reading Cyberattack targets healthcare nonprofit overseeing 13 Colorado facilities (The Record) Malicious packages in open-source repositories are surging (CyberScoop) Octo2 Malware Uses Fake NordVPN, Chrome Apps to Infect Android Devices (HackRead) Hackers Exploiting Veeam RCE Vulnerability to Deploy Ransomware (Cybersecuritynews) Britain, US set up working group to improve children's online safety (Reuters) European Council Adopts Cyber Resilience Act (BankInfoSecurity) New York State Enacts New Cyber Requirements for Hospitals (BankInfoSecurity) FBI created a crypto token so it could watch it being abused (The Register) Man learns he's being dumped via “dystopian” AI summary of texts (Ars Technica) Share your feedback. We want to ensure that you are getting the most out of the podcast. Please take a few minutes to share your thoughts with us by completing our brief listener survey as we continually work to improve the show.  Want to hear your company in the show? You too can reach the most influential leaders and operators in the industry. Here's our media kit. Contact us at cyberwire@n2k.com to request more info. The CyberWire is a production of N2K Networks, your source for strategic workforce intelligence. © N2K Networks, Inc. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of the Pro Audio Suite, the team dives into the ever-evolving landscape of AI and voice licensing, exploring the groundbreaking decision by James Earl Jones to license his voice to Disney. What does this mean for voice actors? And where do we draw the line between legal licensing and exploitation? We also discuss recent lawsuits surrounding AI voice replication, the ethical boundaries of using voices without permission, and what these changes could mean for the future of the industry. The conversation gets heated as Robbo, AP, George "The Tech" Whittam, and Robert Marshall debate whether AI voice replication is an opportunity or a looming threat. With insights from the legal world, current case studies, and expert opinions, this episode is a must-listen for anyone in the audio or voiceover industries. Want to get involved? We've got an exciting Austrian Audio Hi-X20 Headphone Competition running, and it's simple to participate! Download the show's stems and create your own mix for a chance to win. Head over to theproaudiosuite.com to grab the files and get mixing!

Mike Peterson is the director of Mission Sake, a foundation that seeks to empower communities in El Salvador through entrepreneurship and education.  He is also the founder of Bitcoin Beach,Mentions: Four Souls: A Search for Epic Life Jordan Bush is the founder and the Head of Content and Education at TGFB Media and host of the Thank God for Bitcoin Podcast. Find Jordan on Twitter @jmbushwrites.The Thank For Nostr Podcast is a TGFB Media production. TGFB Media exists to educate and equip Christians to understand Bitcoin and use it for the glory of God and the good of people everywhere.

Today we spoke with Corey Hoffstein, a well-known market practitioner with a deep and broad knowledge across quantitative trading & trend following, but also across developing investment products for wider advisor distribution. I'm super interested in almost every aspect of the financial markets, because I feel like a broad and generalist knowledge helps me make better trading and business decisions. Corey hits the nail on the head when he says that a given industry participant may be making optimal business decisions which are sub-optimal trading decisions. If we are aware of this kind of behaviour, it can help shape the way we trade. More than that, understanding market participants, infrastructure, technology, business motivations, and so on, is critical to effective trading. At a basic level, this would include knowing the exact differences between the execution of a market versus a limit order for example. It builds from there, but the point is, it doesn't hurt you to gain more and more knowledge of how the markets ‘actually work'. So much more over on the website: www.thealgorithmicadvantage.com

An alien invasion strategy might work best if they infiltrate and replicate within the human populace. Replication would be part of their reproductive process, but they infiltrate our economic systems as a platform for the dispersal of their ideas and proposals to eliminate humanity. It does not need to be flashy or even spectacular -- it can be as clandestine as what we have seen depicted in the movie, Invasion of the Body Snatchers and the TV series, The Invaders. These outsiders or aliens do not need to demand meetings with leaders; they become leaders. Tonight on Ground Zero, Clyde Lewis talks with paranormal author and podcaster, Dr. John Stamey about INVASION OF THE OUTSIDERS.Originally Broadcast On 10/3/22

In today's episode, you will learn a series of vocabulary words that are connected to a specific topic. This lesson will help you improve your ability to speak English fluently about a specific topic. It will also help you feel more confident in your English abilities.5 Vocabulary Words Related to the topicEquilibrium (noun): A state of balance between opposing forces or processes.Example sentences: Chemical reactions often reach an equilibrium state where the rates of forward and reverse reactions are equal.A skilled tightrope walker maintains perfect equilibrium on the wire.The gymnast held himself perfectly in equilibrium on the balance beam.Hypothesis (verb): To propose an explanation that can be tested.Example sentences: Scientists hypothesized that a new medication might be effective in treating the disease.Based on the observations, the researchers hypothesized that the climate might be changing.Engineers often hypothesize different solutions before testing them in prototypes.Variable (noun): A factor that is changed in an experiment to observe its effect on another factor.Example sentences: The scientist investigated the effect of light intensity on plant growth, using light intensity as the variable.A well-designed experiment has a clear independent variable and a dependent variable that is measured.Controlling all variables except the one being tested is crucial for drawing valid conclusions.Observation (noun): The act of noticing or perceiving something.Example sentences: Careful observation is essential for scientific inquiry.Astronomers use telescopes to make detailed observations of celestial objects.The doctor made careful observations of the patient's symptoms before making a diagnosis.Replication (noun): Repeating an experiment to confirm the results.Example sentences: Scientific findings are more reliable if the experiment can be replicated by other researchers.Replication helps to ensure that the results were not due to chance or errors.To ensure the effectiveness of the new vaccine, researchers conducted replications of the clinical trials at multiple locations worldwide.A Paragraph using the 5 vocabulary wordsScience isn't about blind guesses. It starts with a puzzling observation, like a plant thriving in shade. This sparks a hypothesis – maybe a certain light level, for plants, is ideal. Scientists then experiment by manipulating a variable while keeping others constant. Careful observation and replication confirm their findings. A combination of observation, variable manipulation, hypothesis testing, and confirmation builds a reliable picture of the world, where explanations find equilibrium with what we see.If you want to sign up for the free daily English vocabulary newsletter, go towww.dailyenglishvocabulary.com

This episode delves into the work of Good Business Lab (GBL), co-founded by Professor Achyuta Adhvaryu. GBL focuses on innovative workplace interventions to improve worker well-being and firm productivity, and it typically evaluates these interventions using Randomized Controlled Trials (RCTs). Show host Gene Tunny and Ach discuss the effectiveness of soft skills training programs and the importance of worker voice in creating a more engaged and productive workforce. They discuss methodological issues regarding RCTs and whether the Hawthorne effect is a concern. Ach is Tata Chancellor's Professor of Economics and Director of the 21st Century India Center at UC San Diego.If you have any questions, comments, or suggestions, please email us at contact@economicsexplored.com  or send a voice message via https://www.speakpipe.com/economicsexplored. About this episode's guest: Professor Achyuta AdhvaryuAchyuta Adhvaryu is the Tata Chancellor's Professor of Economics at the School of Global Policy and Strategy and is the inaugural director of the 21st Century India Center at UC San Diego. Adhvaryu's research interests are in development economics, organizational economics and health economics, and his experience in organizational development make him well-suited to lead our new center. Prior to this role, Adhvaryu was a professor at the University of Michigan and an assistant professor at the Yale School of Public Health.https://gps.ucsd.edu/faculty-directory/achyuta-adhvaryu.htmlWhat's covered in EP251Introduction. (0:00)Achyuta's Early Career and Research in East Africa (1:53)Historical Examples of Private Sector Impact (17:03)Good Business Lab's Approach and Findings (21:45)Methodology and Measurement of Impact (37:56)Hawthorne Effect and Replication of Findings (43:33)Economic Development and Convergence (49:44)TakeawaysSoft skills training can significantly improve productivity, even in blue-collar settings.Worker voice, when effectively harnessed, can reduce turnover and absenteeism while boosting productivity.Good Business Lab demonstrates the practical value of academic research when applied to real-world business challenges.A growing body of evidence supports the integration of worker wellbeing initiatives into business strategies globally.Links relevant to the conversationGood Business Lab:https://goodbusinesslab.org/UC San Diego 21st Century India Center that Ach directs:https://india.ucsd.edu/Full transcripts are available a few days after the episode is first published at www.economicsexplored.com.Lumo Coffee promotion10% of Lumo Coffee's Seriously Healthy Organic Coffee.Website: https://www.lumocoffee.com/10EXPLOREDPromo code: 10EXPLORED 

Tips for Slowing Down Viral ReplicationLow magnesium levels increase disease riskBDNF: The Key to Better Mood, Metabolism, and Weight Controlhttps://www.georgebatista.comGreen Vibrance: vibrance.georgebatista.comWellness Resource: myvitaminresource.com rumble.georgebatista.com Email: Wellnesstalk@protonmail.com

Blaise Agüera y Arcas on the Emergence of Replication and Computation – https://pca.st/g7fd2jen Blaise Agüera y Arcas https://en.wikipedia.org/wiki/Blaise_Ag%C3%BCera_y_Arcas falemos de coração (e da falta de) https://youtube.com/live/lhJ2e-ADNgM via ChatGPT – Aristotle on Storytelling Logic https://chatgpt.com/share/9d393157-2a30-4e43-8553-f03183aae8b0 Energy from Nuclear Waste: Switzerland Approves first Accellerator-Driven Reactor https://youtu.be/rLE0j1PQGPI?si=WIEBVXpfD5w1v2hk The Mysterious Origins of Sapphires Have Finally Been Deciphered http://sciencealert.com/the-mysterious-origins-of-sapphires-have-finally-been-deciphered Photon ... Read more The post a Vida não é um milagre! o cérebro quântico, a transmutação dos elementos appeared first on radinho de pilha.

Understanding how life began on Earth involves questions of chemistry, geology, planetary science, physics, and more. But the question of how random processes lead to organized, self-replicating, information-bearing systems is a more general one. That question can be addressed in an idealized world of computer code, initialized with random sequences and left to run. Starting with many such random systems, and allowing them to mutate and interact, will we end up with "lifelike," self-replicating programs? A new paper by Blaise Agüera y Arcas and collaborators suggests that the answer is yes. This raises interesting questions about whether computation is an attractor in the space of relevant dynamical processes, with implications for the origin and ubiquity of life.Support Mindscape on Patreon.Blog post with transcript: https://www.preposterousuniverse.com/podcast/2024/08/19/286-blaise-aguera-y-arcas-on-the-emergence-of-replication-and-computation/Blaise Agüera y Arcas received a B.A. in physics from Princeton University. He is currently a vice-president of engineering at Google, leader of the Cerebra team, and a member of the Paradigms of Intelligence team. He is the author of the books Ubi Sunt and Who Are We Now?, and the upcoming What Is Intelligence?WebsiteGoogle web pageGoogle Scholar publicationsSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

There are all sorts of molecular tests to tell if you're infected with something specific, but what do you use when you're not sure what you might have? You might use a thermometer as a first step, but wouldn't it be nice if that thermometer was a bit more high tech? In this episode we meet Dr. Nick Meyerson, CEO and co-founder of Darwin Biosciences, who's team is working to develop the “molecular thermometer of the future.” We hear about how this physicist transitioned into molecular biology and then latched onto saliva as a sample of choice to detect early molecular indicator of infection. Nick does a great job of explaining his path leading up to the founding of Darwin Bio, the challenges of founding a company in early 2020, why saliva is their sample of choice, the beautiful simplicity of isothermal amplification methods, and the lesser-known funding routes of working with government agencies like the Defense Threat Reduction Agency (DTRA). Join us as we dive into the molecular nature of non-specific detection of infections, how it's done using no electricity, it's potential applications, and what the future holds for this field. Nick also shares lessons learned and some insights on the value of mentors and a lifelong curiosity. Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague.  Download Transcripts: Speaking of Mol Bio Podcast | Thermo Fisher Scientific - US Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology.

Viral vectors are a cornerstone of gene therapy and many employ experts in the viral vector services space to help design and produce their specialty vectors. These service providers are experts at making sure you get the vector you want with a titer and purity you need for your application. We're joined in this episode by Dr. Cliff Froelich, Head of Analytical Development for a viral vector services provider. Cliff and his team work with AAV, lentivirus, and other vectors to support multiple, and simultaneous, client projects. Specifically, we dive into how they use various analytical and molecular methods to monitor and assess identity, strength, purity, impurities, potency, efficiency, empty/full ratios, safety, and more. As you might expect, it's not a one-method-does-it-all approach or solution. Yes, digital PCR is in the mix here, and Cliff does a great job of outlining where it shines relative to the other methods they use regularly in their GMP practice. In our career corner portion, you'll hear about Cliff's circuitous career path, which includes stints in the poultry industry and time as a clinical dietitian. Through it all, and into his current role, Cliff brings a passion and genuine interest for the science and its potential to affect lives. Visit the Absolute Gene-ius pageto learn more about the guests, the hosts, and the Applied Biosystems QuantStudio Absolute Q Digital PCR System. 

Ahmed and Eric discuss the major steps in DNA replication, how it differs in eukaryotes vs. prokaryotes and viruses, and make real world connections to cancer in the process. Want to learn more? Shoot us a text at 415-855-4435 or email us at podcast@jackwestin.com!

In this episode, the Get Stacked team, consisting of Rodrigo Gordillo, Corey Hoffstein, Adam Butler and Mike Philbrick delve into the intricacies of Return Stacking, market trends, and the impact of taxes on investment strategies. They provide detailed insights into their research and findings, discussing the implications of their work for the investment landscape.

In this episode, we continue our discussion of replications. We talk about how to analyze replication studies, which studies are worth replicating, and what is the status of replications in other scientific disciplines.    Shownotes Mack, R. W. (1951). The Need for Replication Research in Sociology. American Sociological Review, 16(1), 93–94. https://doi.org/10.2307/2087978 Smith, N. C. (1970). Replication studies: A neglected aspect of psychological research. American Psychologist, 25(10), 970–975. https://doi.org/10.1037/h0029774 Sidman, M. (1960). Tactics of Scientific Research: Evaluating Experimental Data in Psychology (New edition). Cambridge Center for Behavioral. Ebersole, C. R., Mathur, M. B., Baranski, E., Bart-Plange, D.-J., Buttrick, N. R., Chartier, C. R., Corker, K. S., Corley, M., Hartshorne, J. K., IJzerman, H., Lazarević, L. B., Rabagliati, H., Ropovik, I., Aczel, B., Aeschbach, L. F., Andrighetto, L., Arnal, J. D., Arrow, H., Babincak, P., … Nosek, B. A. (2020). Many Labs 5: Testing Pre-Data-Collection Peer Review as an Intervention to Increase Replicability. Advances in Methods and Practices in Psychological Science. https://doi.org/10.1177/2515245920958687 Isager, P. M., van Aert, R. C. M., Bahník, Š., Brandt, M. J., DeSoto, K. A., Giner-Sorolla, R., Krueger, J. I., Perugini, M., Ropovik, I., van 't Veer, A. E., Vranka, M., & Lakens, D. (2023). Deciding what to replicate: A decision model for replication study selection under resource and knowledge constraints. Psychological Methods, 28(2), 438–451. https://doi.org/10.1037/met0000438 Aldhous, P. (2011). Journal rejects studies contradicting precognition. New Scientist. https://www.newscientist.com/article/dn20447-journal-rejects-studies-contradicting-precognition/ Stanley, D. J., & Spence, J. R. (2014). Expectations for Replications: Are Yours Realistic? Perspectives on Psychological Science, 9(3), 305–318. https://doi.org/10.1177/1745691614528518 Simonsohn, U. (2015). Small telescopes: Detectability and the evaluation of replication results. Psychological Science, 26(5), 559–569. https://doi.org/10.1177/0956797614567341 Nosek, B.A., Errington, T.M. (2017) Reproducibility in Cancer Biology: Making sense of replications. eLife 6:e23383. https://doi.org/10.7554/eLife.23383      

In today's episode, we delve into how AI-enhanced software Meliorator was used to spread Russian disinformation on X (formerly Twitter), as detailed by the US Justice Department (DoJ). We also discuss the ViperSoftX malware disguising as eBooks on torrents, uncovered by Trellix security researchers, and examine how the new EstateRansomware group exploited a Veeam Backup Software vulnerability to launch attacks. Lastly, we cover Check Point and Morphisec's findings on zero-day vulnerabilities CVE-2024-38112 and CVE-2024-38021, and the urgency of applying Microsoft's recent patches. Video Episode: https://youtu.be/ZeL8oo0HRBY Original URLs: https://www.helpnetsecurity.com/2024/07/10/russian-disinformation-x/ https://thehackernews.com/2024/07/vipersoftx-malware-disguises-as-ebooks.html https://thehackernews.com/2024/07/new-ransomware-group-exploiting-veeam.html https://www.helpnetsecurity.com/2024/07/10/cve-2024-38112-cve-2024-38021/ Sign up for digestible cyber news delivered to your inbox: news.thedailydecrypt.com Thanks to Jered Jones for providing the music for this episode. https://www.jeredjones.com/ Logo Design by https://www.zackgraber.com/ Tags: Russian disinformation, AI-enhanced software, Meliorator, social media bot farms, US Justice Department, domain seizure, digital army, fake personas, propaganda, ViperSoftX, malware, eBooks, torrent sites, Common Language Runtime, AutoIt, PowerShell commands, EstateRansomware, Veeam Backup & Replication, FortiGate firewall, vulnerability, ransomware attack, Check Point Research, Windows, CVE-2024-38112, Microsoft, patch, remote code execution, deceptive .url files, cyber threats. Search Phrases: Russian disinformation bot farms AI-enhanced software in social media How Meliorator spreads fake news Protect against ViperSoftX malware Ransomware exploiting Veeam vulnerability FortiGate firewall security flaw Latest cyber threats Check Point Research CVE-2024-38112 vulnerability details Microsoft's latest security patch Prevent remote code execution attacks

By Lee Herrick

In the next two episodes, we will discuss replication studies, which are essential to building reliable scientific knowledge.   Shownotes Mack, R. W. (1951). The Need for Replication Research in Sociology. American Sociological Review, 16(1), 93–94. https://doi.org/10.2307/2087978 Smith, N. C. (1970). Replication studies: A neglected aspect of psychological research. American Psychologist, 25(10), 970–975. https://doi.org/10.1037/h0029774 Sidman, M. (1960). Tactics of Scientific Research: Evaluating Experimental Data in Psychology (New edition). Cambridge Center for Behavioral. Ebersole, C. R., Mathur, M. B., Baranski, E., Bart-Plange, D.-J., Buttrick, N. R., Chartier, C. R., Corker, K. S., Corley, M., Hartshorne, J. K., IJzerman, H., Lazarević, L. B., Rabagliati, H., Ropovik, I., Aczel, B., Aeschbach, L. F., Andrighetto, L., Arnal, J. D., Arrow, H., Babincak, P., … Nosek, B. A. (2020). Many Labs 5: Testing Pre-Data-Collection Peer Review as an Intervention to Increase Replicability. Advances in Methods and Practices in Psychological Science. https://doi.org/10.1177/2515245920958687 Isager, P. M., van Aert, R. C. M., Bahník, Š., Brandt, M. J., DeSoto, K. A., Giner-Sorolla, R., Krueger, J. I., Perugini, M., Ropovik, I., van 't Veer, A. E., Vranka, M., & Lakens, D. (2023). Deciding what to replicate: A decision model for replication study selection under resource and knowledge constraints. Psychological Methods, 28(2), 438–451. https://doi.org/10.1037/met0000438 Aldhous, P. (2011). Journal rejects studies contradicting precognition. New Scientist. https://www.newscientist.com/article/dn20447-journal-rejects-studies-contradicting-precognition/ Stanley, D. J., & Spence, J. R. (2014). Expectations for Replications: Are Yours Realistic? Perspectives on Psychological Science, 9(3), 305–318. https://doi.org/10.1177/1745691614528518 Simonsohn, U. (2015). Small telescopes: Detectability and the evaluation of replication results. Psychological Science, 26(5), 559–569. https://doi.org/10.1177/0956797614567341  

In Episode #34, host John Sherman talks with Charbel-Raphaël Segerie, Executive Director, Centre pour la sécurité de l'IA. Among the very important topics covered: autonomous AI self replication, the potential for warning shots to go unnoticed due to a public and journalist class that are uneducated on AI risk, and the potential for a disastrous Yan Lecunnification of the upcoming February 2025 Paris AI Safety Summit.   Please Donate Here To Help Promote For Humanity https://www.paypal.com/paypalme/forhumanitypodcast This podcast is not journalism. But it's not opinion either. This is a long form public service announcement. This show simply strings together the existing facts and underscores the unthinkable probable outcome, the end of all life on earth.  For Humanity: An AI Safety Podcast, is the accessible AI Safety Podcast for all humans, no tech background required. Our show focuses solely on the threat of human extinction from AI. Peabody Award-winning former journalist John Sherman explores the shocking worst-case scenario of artificial intelligence: human extinction. The makers of AI openly admit it their work could kill all humans, in as soon as 2 years. This podcast is solely about the threat of human extinction from AGI. We'll meet the heroes and villains, explore the issues and ideas, and what you can do to help save humanity. For Humanity Theme Music by Josef Ebner Youtube: https://www.youtube.com/channel/UCveruX8E-Il5A9VMC-N4vlg Website: https://josef.pictures RESOURCES: Charbel-Raphaël Segerie's Less Wrong Writing, much more on many topics we covered! https://www.lesswrong.com/users/charbel-raphael BUY STEPHEN HANSON'S BEAUTIFUL AI RISK BOOK!!! https://stephenhansonart.bigcartel.com/product/the-entity-i-couldn-t-fathom JOIN THE FIGHT, help Pause AI!!!! Pause AI Join the Pause AI Weekly Discord Thursdays at 2pm EST   / discord   https://discord.com/invite/pVMWjddaW7 22 Word Statement from Center for AI Safety Statement on AI Risk | CAIS https://www.safe.ai/work/statement-on-ai-risk Best Account on Twitter: AI Notkilleveryoneism Memes  https://twitter.com/AISafetyMemes TIMESTAMPS: **The threat of AI autonomous replication (00:00:43)** **Introduction to France's Center for AI Security (00:01:23)** **Challenges in AI risk awareness in France (00:09:36)** **The influence of Yann LeCun on AI risk perception in France (00:12:53)** **Autonomous replication and adaptation of AI (00:15:25)** **The potential impact of autonomous replication (00:27:24)** **The dead internet scenario (00:27:38)** **The potential existential threat (00:29:02)** **Fast takeoff scenario (00:30:54)** **Dangers of autonomous replication and adaptation (00:34:39)** **Difficulty in recognizing warning shots (00:40:00)** **Defining red lines for AI development (00:42:44)** **Effective education strategies (00:46:36)** **Impact on computer science students (00:51:27)** **AI safety summit in Paris (00:53:53)** **The summit and AI safety report (00:55:02)** **Potential impact of key figures (00:56:24)** **Political influence on AI risk (00:57:32)** **Accelerationism in political context (01:00:37)** **Optimism and hope for the future (01:04:25)** **Chances of a meaningful pause (01:08:43)**

Smith, N. C. (1970). Replication studies: A neglected aspect of psychological research. American Psychologist, 25(10), 970–975. https://doi.org/10.1037/h0029774

In this podcast episode, Petra Molnar, a lawyer and anthropologist specializing in border technologies, emphasized the critical point that technology is far from neutral. She highlighted how technology mirrors and perpetuates power dynamics in society, underscoring the significant impacts it can have on individuals if not carefully considered during the innovation process. This concept is essential to grasp as it illuminates the broader implications of technological advancements on society.Replication of PowerPower Imbalance: Technology often mirrors and reinforces existing power imbalances within society. Those with more resources and influence can shape the development and deployment of technology, potentially leading to biases and discriminatory outcomes.Impact on Marginalized Groups: The replication of power dynamics in technology can disproportionately affect marginalized groups, such as refugees, migrants, and individuals facing legal proceedings. These vulnerable populations may bear the brunt of technological solutions that prioritize control and surveillance over human rights and dignity.Considerations for InnovationEthical Frameworks: Molnar suggested that considering ethical frameworks is a starting point for technologists. However, she cautioned that ethics alone may not be sufficient to address the complex societal implications of technology.Regulation and Governance: While ethics provide a moral compass, regulatory frameworks are necessary to enforce accountability and ensure that technology serves the common good. Molnar highlighted the importance of robust regulations tailored to specific contexts to address the real-world impacts of technology.Collaboration and Multidisciplinary ApproachInclusive Innovation: Molnar stressed the need for collaboration between different disciplines and lived experiences in the innovation process. By engaging with diverse perspectives, including those directly impacted by technology, technologists can gain a deeper understanding of the potential consequences of their innovations.Human-Centered Design: Taking a human-centered approach to technology development involves prioritizing the well-being and rights of individuals over technological advancement. By centering the needs and experiences of users, technologists can create solutions that empower and benefit society as a whole. Supported by: https://skykick.com/mspradio/ https://getinsync.ca/mspradio/  All our Sponsors: https://businessof.tech/sponsors/   Looking for a link from the stories? The entire script of the show, with links to articles, are posted in each story on https://www.businessof.tech/ Do you want the show on your podcast app or the written versions of the stories? Subscribe to the Business of Tech: https://www.businessof.tech/subscribe/ Support the show on Patreon: https://patreon.com/mspradio/ Want our stuff? Cool Merch? Wear “Why Do We Care?” - Visit https://mspradio.myspreadshop.com Follow us on:LinkedIn: https://www.linkedin.com/company/28908079/YouTube: https://youtube.com/mspradio/Facebook: https://www.facebook.com/mspradionews/Instagram: https://www.instagram.com/mspradio/TikTok: https://www.tiktok.com/@businessoftechBluesky: https://bsky.app/profile/businessoftech.bsky.social

Guy and Eitan continue discussing HADR solutions. But this time focusing on Transactional Replication, its cons and pros and potential use cases. Also, some important announcements from Microsoft about Azure SQL! Relevant links: Data API builder General Availability (microsoft.com) Build REST API with Azure Data API Builder (DAB) (mssqltips.com) Zero ETL, Near-real time replication, Mirroring Azure SQL Databases in Fabric (microsoft.com) Announcing EAP for Vector Support in Azure SQL Database - Azure SQL Devs' Corner (microsoft.com) Update Policy for Azure SQL Managed Instance - Microsoft Community Hub Transactional Replication - SQL Server | Microsoft Learn MadeiraData/ReplicationManagementMechanism: Use SQL Server database tables to manage and configure Transactional Replication, and set it up easily between publishers and subscribers using stored procedures (github.com)

Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: We might be dropping the ball on Autonomous Replication and Adaptation., published by Charbel-Raphael Segerie on May 31, 2024 on The AI Alignment Forum. Here is a little Q&A Can you explain your position quickly? I think autonomous replication and adaptation in the wild is under-discussed as an AI threat model. And this makes me sad because this is one of the main reasons I'm worried. I think one of AI Safety people's main proposals should first focus on creating a nonproliferation treaty. Without this treaty, I think we are screwed. The more I think about it, the more I think we are approaching a point of no return. It seems to me that open source is a severe threat and that nobody is really on the ball. Before those powerful AIs can self-replicate and adapt, AI development will be very positive overall and difficult to stop, but it's too late after AI is able to adapt and evolve autonomously because Natural selection favors AI over humans. What is ARA? Autonomous Replication and Adaptation. Let's recap this quickly. Today, generative AI functions as a tool: you ask a question and the tool answers. Question, answer. It's simple. However, we are heading towards a new era of AI, one with autonomous AI. Instead of asking a question, you give it a goal, and the AI performs a series of actions to achieve that goal, which is much more powerful. Libraries like AutoGPT or ChatGPT, when they navigate the internet, already show what these agents might look like. Agency is much more powerful and dangerous than AI tools. Thus conceived, AI would be able to replicate autonomously, copying itself from one computer to another, like a particularly intelligent virus. To replicate on a new computer, it must navigate the internet, create a new account on AWS, pay for the virtual machine, install the new weights on this machine, and start the replication process. According to METR, the organization that audited OpenAI, a dozen tasks indicate ARA capabilities. GPT-4 plus basic scaffolding was capable of performing a few of these tasks, though not robustly. This was over a year ago, with primitive scaffolding, no dedicated training for agency, and no reinforcement learning. Multimodal AIs can now successfully pass CAPTCHAs. ARA is probably coming. It could be very sudden. One of the main variables for self-replication is whether the AI can pay for cloud GPUs. Let's say a GPU costs $1 per hour. The question is whether the AI can generate $1 per hour autonomously continuously. Then, you have something like an exponential process. I think that the number of AIs is probably going to plateau, but regardless of a plateau and the number of AIs you get asymptotically, here you are: this is an autonomous AI, which may become like an endemic virus that is hard to shut down. Is ARA a point of no return? Yes, I think ARA with full adaptation in the wild is beyond the point of no return. Once there is an open-source ARA model or a leak of a model capable of generating enough money for its survival and reproduction and able to adapt to avoid detection and shutdown, it will be probably too late: The idea of making an ARA bot is very accessible. The seed model would already be torrented and undeletable. Stop the internet? The entire world's logistics depend on the internet. In practice, this would mean starving the cities over time. Even if you manage to stop the internet, once the ARA bot is running, it will be unkillable. Even rebooting all providers like AWS would not suffice, as individuals could download and relaunch the model, or the agent could hibernate on local computers. The cost to completely eradicate it altogether would be way too high, and it only needs to persist in one place to spread again. The question is more interesting for ARA with incomplete adaptation capabilities. It is likely th...

There is always so much people want to know about AAC. Today I talked with BCBAs, LingLy Tan and Jane Button. LingLy is the CEO of AAC software company Linggo, created to build and encourage language beyond simple requests.As I've mentioned many times, keeping up with the current research is one of the largest barriers for providers in the field. AAC is one element that is always changing, and it is so necessary to be aware of the latest information. During our conversation, LingLy and Jane shared some of their favorite research, including from some authors I've talked to on the podcast.While software for AAC does matter, LingLy highlights that it is a much smaller piece compared to the training to actually teach and use AAC. In fact, Linggo is working on a new training program, where they streamline the translation and application of current research into implementation with AAC with both live hands on options and self paced recordings.Be sure to take a look at the articles and previous episodes all about the current research on AAC. #autism #speechtherapy What's Inside:How to stay up to date with current technology and research in AAC?An AAC software focused on expanding language beyond simple requests.Recommended articles for the latest research in AAC.Linggo's new training to embed research and implementation when teaching AAC.Mentioned In This Episode:Matrix training to teach tacts using speech generating devices: Replication and extensionTransitioning from a low- to high-tech Augmentative and Alternative Communication (AAC) system: effects on augmented and vocal requestingCore vocabulary lists for young children and considerations for early language development: a narrative reviewExamining core vocabulary with language development for early symbolic communicatorsEpisode #121: Core Vocabulary and Typical Language Development with Allison Bean and Bethany Frick Semmler - ABA SpeechEpisode #111: Matrix Training with Dr. Sarah Frampton - ABA SpeechJoin the ABA SPEECH Connection Membership

The penultimate episode of the DNA Papers podcast series revisits a paper that demonstrated the semiconservative mode of DNA replication, which had been predicted by complementary base-paired double helix model of the molecule discussed in episode 13 of this series: Meselson, Matthew, and Franklin W. Stahl. “The replication of DNA in Escherichia coli.” Proceedings of the National Academy of Sciences 44, no. 7 (July 15, 1958): 671–82. https://doi.org/10.1073/pnas.44.7.671 The papers offers the details an experiment designed and performed by a pair of young molecular biologists, Matthew Meselson and Franklin Stahl at Caltech. They deployed the newly developed technique of density gradient centrifugation in combination with the use of heavy isotopes of nitrogen to show that during the replication of a DNA molecule, each progeny helix contained one strand that was conserved, or passed down directly from the parent and one new strand synthesized from the conserved template. Listen to our expert guests from different disciplines as they share their insights into what has been described as “the most beautiful experiment in biology”: Allan Franklin University of Colorado Boulder Michel Morange IHPST, Université Paris I William C. Summers Yale University Janina Wellmann Max Planck Institute for the History of Science Recorded on March 27, 2024 For additional resources on this topic, please see https://www.chstm.org/video/144

Why are business introductions so valuable? In this episode, Adam Torres interviews Joel Bash, President at Joel Bash and Company. Explore Joel Bash and Company and replicate success. Follow Adam on Instagram at https://www.instagram.com/askadamtorres/ for up to date information on book releases and tour schedule. Apply to be a guest on our podcast: https://missionmatters.lpages.co/podcastguest/ Visit our website: https://missionmatters.com/ More FREE content from Mission Matters here: https://linktr.ee/missionmattersmedia

Nikolay and Michael are joined by Sai Srirampur, CEO and Co-founder of PeerDB, to discuss how to overcome several logical replication issues. They discuss the protocol versions, minimising slot growth, minimising lag, and some tips and tricks for scaling things well. Here are some links to things they mentioned:PeerDB https://www.peerdb.io/Our episode on logical replication https://postgres.fm/episodes/logical-replicationExploring versions of the Postgres logical replication protocol (blog post by Sai) https://blog.peerdb.io/exploring-versions-of-the-postgres-logical-replication-protocol Logical Streaming Replication Protocol https://www.postgresql.org/docs/current/protocol-logical-replication.htmlREPLICA IDENTITY FULL https://www.postgresql.org/docs/current/sql-altertable.html#SQL-ALTERTABLE-REPLICA-IDENTITYOn the performance impact of REPLICA IDENTITY FULL in Postgres (blog post by Xata) https://xata.io/blog/replica-identity-full-performance max_slot_wal_keep_size https://www.postgresql.org/docs/current/runtime-config-replication.html#GUC-MAX-SLOT-WAL-KEEP-SIZE Active Active in Postgres 16 (blog post by Crunchy Data) https://www.crunchydata.com/blog/active-active-postgres-16 pgEdge https://www.pgedge.com/DistSQL (term used by Mark Callaghan) https://smalldatum.blogspot.com/2023/07/keeping-up-with-sql-dbms-market.html Five tips on Postgres logical decoding (blog post by Sai) https://blog.peerdb.io/five-tips-on-postgres-logical-decodingPG Slot Notify: Monitor Postgres Slot Growth in Slack (blog post by PeerDB) https://blog.peerdb.io/pg-slot-notify-monitor-postgres-slot-growth-in-slack~~~What did you like or not like? What should we discuss next time? Let us know via a YouTube comment, on social media, or by commenting on our Google doc!~~~Postgres FM is brought to you by:Nikolay Samokhvalov, founder of Postgres.aiMichael Christofides, founder of pgMustardWith special thanks to:Jessie Draws for the amazing artwork 

Show Notes: In this conversation with Will Bachman, Ivan Oransky, a co-founder of Retraction Watch, shares his experience as a medical journalist and with Retraction Watch. Ivan explains that his friend and co-founder, Adam Marcus had uncovered a massive story about scientific fraud in Western Massachusetts, where an anesthesiologist had made up all clinical data. Adam, who was managing editor of an publication called Anesthesiology News got the scoop on the story, and Ivan, who was impressed with the story, suggested they start a blog about retraction notices, it turned out there were far more happening than previously thought.  13 and a half years later, Retraction Watch is still going strong and has a large audience. Adam and Ivan are volunteers but have four staff two of whom run a database of retractions that was recently acquired by CrossRef, a nonprofit that tracks scientific data and papers. The other two staff continue to contribute to the journalism work they started 13 and a half years ago, while Ivan and Adam still supervisor edit and direct it. How to Evaluate an Article Ivan shares his advice on how to evaluate an article in a medical journal or any published article. He emphasizes the importance of showing one's work and examining the evidence used to reach a conclusion. He explains that, when looking at articles, it is crucial to consider the original sources, citations, and the journal's track record of quality. He also emphasizes the importance of humility in making claims and not making pronouncements about things he or she doesn't know anything about. He also warns against trusting credentials to suggest expertise, as it can be misleading, Ivan shares the example of a time when he was asked to peer review papers about COVID-19, simply because he had co-authored a letter about retractions of work. However, he is not an expert on the subject. Ivan believes that an expert should only be asked to peer review papers that they believe are likely to hold up or should not be published.  Leading Causes of Retraction Ivan explains that factors that commonly lead to a retraction. Two-thirds of retractions are for misconduct. This number is consistent across various works and he goes on to explain that there are several definitions of misconduct to take into consideration, including fabrication, falsification, and plagiarism. About 20 percent of the time, it's due to a what's known as honest error, and Ivan offers a few examples.  The deeper cause is the requirement that researchers must publish in certain places to get a job in academia, tenure, promotion, and prizes. This drives people to do all sorts of things, and while this drives most people to work harder and try to work more efficiently, others may take a different approach. In fact, Ivan states that 2 percent of researchers admit to committing misconduct.  The Replication Crisis Ivan talks about the replication crisis, which has been a topic of interest in the social sciences and hard sciences. When Retraction Watch was first launched, there were about 400 retractions from journals a year. Last year, there were more than 10,000, a big increase despite the rising number of papers published. The root cause of this issue is the same problem: replications are not new research or findings and should be cherished and prized, but they are not. Big journals don't like to publish replications, so they don't reward new research. To get into a big journal, researchers need to publish new research, which is simple behavioral incentive economics. The discussion turns to incentives for people to write about scientific misconduct and fraud. Ivan states that, while there is more incentive not to write retractions, he cites a page on Retraction Watch that has dozens of stories from people committed to revealing issues with research, including well-known figures. These individuals face legal risks, such as lawsuits, and are usually not paid for this work.  The conversation also touches on the potential negative repercussions of challenging senior professionals in their field, such as professors or presidents of universities. However, most of these individuals do not work in science anymore, or their career trajectory is not dependent on pleasing or failing to displease senior members of academia. These individuals often publish on sites like PubPeer, which allows users to leave comments on published studies. This helps expose the issues and claims in the media, helping to raise awareness and support for those who need help. Retraction Watch offers resources and social media platforms for those interested in learning more about the topic. They welcome feedback and story tips, and they are open to sharing more information about their work. Timestamps: 01:03 Scientific fraud and retractions  04:41 Evaluating credibility in scientific articles and peer review 09:10 Research retractions and the root causes 13:05 Replication crisis in science and the challenges faced by those uncovering fraud 17:18 Academic misconduct and whistleblowers Links: Website: https://retractionwatch.com/ Unleashed is produced by Umbrex, which has a mission of connecting independent management consultants with one another, creating opportunities for members to meet, build relationships, and share lessons learned. Learn more at www.umbrex.com.

Join Scott Hanselman as he sits down with Sai Srirampur, as they explore the intricacies of Postgres Replication and how it can be turbocharged using PeerDB. In the realm of databases, Postgres Replication is like a well-choreographed dance between servers. Sai takes us behind the scenes, revealing the steps involved and how it can be made faster and cheaper.https://www.peerdb.io/

Why have we not found the cure for cancer yet? Neil deGrasse Tyson, Chuck Nice, and Gary O'Reilly explore paradigm shifts in cancer treatment, molecular biology, and a promising new cancer drug AOH1996 with City of Hope cancer researcher Dr. Linda Malkas. NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free.Thanks to our Patrons Willie Bass, Nicholas A Jones, Edwin Goel, Joe Gibbs, Shane Alexander, Keith Goodman, and James Kuntz for supporting us this week.Photo Credit: Dr. Cecil Fox (Photographer), Public domain, via Wikimedia Commons