Podcasts about uhn

A Toronto hospital network has a plan to recruit the best and brightest medical scientists from the U.S. and around the world, as funding cuts and layoffs put a chill on research south of the border. Matt Galloway discusses what Canada stands to gain with Kevin Smith, president and CEO of University Health Network; and Brad Wouters, UHN's executive vice-president of science and research.

Health is driven by more than what happens in a clinic or the operating room, it is driven by long-standing system decisions. One of the ways Dr. Andrew Boozary and the UHN are impacting health equity is through the inception of Dunn House, Canada's first hospital-led supportive housing initiative. This unique model couples health and social care by improving health outcomes for unhoused Torontonians, embedding concreate solutions to UHN's most vulnerable patients. “This brings a wholistic approach to healthcare, that it's not just about access to physicians and nurses, that there's really a more integrated way to think about health, and Dunn House is real action on that kind of thinking and philosophy.” In this exciting episode of Healthcare Change Makers, learn more about UHN's social medicine program, the impact of Dunn house, and the value of partnership with community organizations. And stay tuned until the end to hear Dr. Boozary's take on medical TV dramas and which musician helps give him an energy boost.   Quotables: “How do we recenter humanity in healthcare for those of us who work in the system, for families, for caregivers, and most ultimately for patients.” “Health and so much protection in society are system choices or policy choices, and it's not about individual failures but how resources, protection, power, and privilege, really play roles in worse health outcomes.” “The idea that some lives matter more than others is the fundamental issue or injustice that we face in the world.” “Whatever it is that grips you, that you lose sleep over, that makes your blood boil, whatever it is that you feel this sense of injustice, to not lose that feeling and energy, and pursue it however you can.” “If the University Health Network is really serious (which they are) about advancing health and not being the university healthcare network, but truly about heath, we need to be able to take different approaches in how we reach people… who need it most.” “Housing and health are inextricably linked.” “This is what I think is really the secret sauce, is the partnership and the willingness to think differently about the solution – that the band-aid fixes are not going to work. That there is a moral distress that becomes imposed on health workers seeing the same revolving door… and how can we start embedding, building concrete solutions for people.” “I think it's really important to shout out the incredible work of community health centres that have been leading social medicine work for 50 years or more.” “Preventing some of these feelings of despair or burnout is understanding this is part of the work, and how do you hold and create space for some of it, because trying to deny it or push it out or discount it has its own downsides as well.” “We don't need a magic wand, we need real investment in people, and that we can see magical outcomes if we actually dedicate that focus.” Mentioned in this Episode: ·       HIROC's 2025 Conference, Save the Date ·       University Health Network (UHN) ·       Dr. Kevin Smith ·       UHN's Gattuso Centre for Social Medicine ·       UHN's Dunn House ·       Dr. Jeff Turnbull ·       Wendy Muckle ·       Dr. Paul Farmer ·       Emmanuelle Gattuso ·       City of Toronto ·       Fred Victor ·       The United Way ·       Angela Robertson, Parkdale Queen West Community Health Centre ·       Camden Coalition ·       Kendrick Lamar ·       The Knick (tv drama) ·       The Pitt (tv drama) Access More Interviews with Healthcare Leaders at HIROC.com/podcast Follow us on LinkedIn and Instagram, and listen on Apple Podcasts, Spotify, or wherever you get your favourite podcasts. Email us at Communications@HIROC.com.

00:00: Outline 00:53: P1, P2, P3 03:14: Feasibility study 04:35: DJ Seo comments 06:20: Academic work 07:18: Bad reporting- Rachel Levy 10:15: Canada trial- international expansion 12:02: Elon talk at CNS 13:46: Please follow and subscribe! Jan 8, 2025: CES by Mark Penn, CEO of Stagwell: https://x.com/ElonClipsX/status/1877222791713337623 Jan 7, 2025: Elon Announces More International Expansion: https://x.com/NeuraPod/status/1876708688242589775 Nov 25, 2024: Neuralink's CONVOY Study Announcement: https://x.com/neuralink/status/1861107594645119006 Nov 22, 2024: Romina's Offer: https://x.com/RominaNejad/status/1859996818601652667 Nov 20, 2024: Neuralink's Canadian Trial Announcement: https://x.com/neuralink/status/1859321866944401727 Nov 20, 2024: University Health Network Announcement: https://x.com/UHN/status/1859324169072353488 Sep 29, 2024: Elon Talks at Congress of Neurosurgeons Meeting: https://youtu.be/huxf36QKbI0?si=oQeksONwxG24Iv9G&t=1710 April 2022: Neura Pod Episode: https://www.youtube.com/watch?v=3qUhEXwrL74&t=1003s&ab_channel=NeuraPod%E2%80%93Neuralink Apply for Neuralink's Patient Registry: https://neuralink.com/patient-registry/

On a nice October day - during the week Miroki was due to be wed - André forced her to drop all her plans to attend the grand cru culinary wine festival in support of UHN programs hosted by Halpern. 2024 was the 20th incarnation of this festival and raised 38 million in support of the new surgical tower at Toronto Western Hospital. That being said - Grand Cru is also a great place to taste some wines that may be out of reach for some...We had the chance to taste and chat with David Butterfield of his eponymous wineryTaste through the line up of Caduceus Cellars wines Discover whether or not California can rival the wines of Burgundy by tasting the wines of Racines next to the wines for Domaine de MontilleHave a very laid back conversation with Alexandre Leger of the iconic Domaine PonsotWe fought the mob to taste the Champagne of Pol Roger - but instead discovered the bubbles of Pierre PaillardThank you to Mika from Halpern for allowing us early access to the event to get some interview.You can follow Miroki on Instagram @9ouncespleaseYou can follow André on Instagram @andrewinereview Hosted on Acast. See acast.com/privacy for more information.

In this bonus episode, we delve into the life-changing journey of Carmen Chu, a cancer survivor and mother who was diagnosed with sleep apnea. Carmen shares her struggles with interrupted sleep, fatigue, and the impact on her daily life. She discusses her experience with sleep tests and the transformative benefits of using a CPAP machine.Additional ResourcesUHN's Centre for Sleep Health and ResearchDr. Frances Chung named UHN Inventor of the YearDr. Douglas Bradley featured in KITE Research spotlight: Use of non-invasive breathing device to alleviate obstructive and central sleep apnea improves quality of life The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

In this bonus episode, we share Adriana Salazar's powerful and emotional journey. Adriana, a 40-year-old mother and wife, first experienced the pain on her honeymoon in Portugal. The pain disappeared but returned during her pregnancy, escalating to a point where she couldn't smile or eat. Despite seeing multiple specialists, she received her diagnosis only after her daughter's birth.After undergoing microvascular decompression surgery, Adriana finally found relief. Her journey from debilitating pain and struggles with misdiagnoses to reclaiming her life highlights the resilience and strength of those battling trigeminal neuralgia.Additional ResourcesDr. Hodaie was interviewed on Season 1 of Your Complex Brain – "The most painful brain disease you've never heard of"Toronto neurosurgeon marks 1,000th operation treating 'excruciating' facial pain syndrome (CBC story)Dr. Hodaie recounts her journey from new immigrant to neurosurgeon (video)Brain Aging in Fast Forward (UHN Research article)Dr. Hodaie was a featured speaker at KBI's first-ever 'International Day of Women and Girls in Science' event (video)The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Today, we're diving into the deeply personal journey of Julianne Hazelwood, a journalist and new mother, who has lived with epilepsy since her early teenage years. Julianne shares her transformational experience of motherhood, the challenges of managing epilepsy, and how The Lullaby Project—a group that brings together expectant mothers with songwriters to create a song for their baby—became a therapeutic outlet during her pregnancy.Additional ResourcesThe Lullaby ProjectThe Lullaby Project PlaylistJulianne Hazlewood's CBC radio documentary on White Coat Black ArtDr. Esther Bui was interviewed in Season 2 of Your Complex Brain podcast - A New Era in Women's Brain Health: Closing the Gap on Delayed DiagnosisAdvancing Women's Neurology through Education, Research and Advocacy (U of T story featuring Dr. Esther Bui & Dr. Aleksandra Pikula)Dr. Esther Bui was featured in UHN Foundation 'Know Your Heroes' seriesThe Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Rodrigo Reis, General Manager of UCB Pharma Canada, gives insights into fostering innovation in pharma, collaborating with UHN to expedite diagnoses, and entering the rare disease space with new innovative therapeutics. Get full access to NPC Healthbiz Weekly at healthbiz.substack.com/subscribe

In this powerful and inspiring bonus episode, we delve into the remarkable journey of Shruti Kothari, a 34-year-old actress and stroke survivor. On March 7, 2020, just before the pandemic shook the world, Shruti experienced a stroke while hosting friends at her apartment. Her left side went numb, and thanks to a quick-thinking friend trained in recognizing stroke symptoms, paramedics were called immediately. Shruti's story is not just one of survival but thriving against all odds. She talks about her rehabilitation process, an innovative program that helped her regain movement in her arm, and her determination to continue her acting career. Despite the challenges, Shruti's optimism and drive to give back to the community shine through. Additional ResourcesUHN's Stroke Prevention ClinicDr. Pikula was interviewed in the Your Complex Brain episode "The Rise of Stroke in Young Adults"UHN Foundation video "Shruti's journey back to the stage, with some help from Team UHN"Heart and Stroke Foundation of Canada – Women's Digital HubWorld Stroke Academy podcast featuring Dr. LindsayThe Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

In this bonus episode, we dive deeper into the lived experience of Matthew Cote, a teacher and advocate for those living with learning disabilities, including reading disabilities. Matthew shares his personal journey, detailing how his reading disability impacted his early years, from struggling to decode words and feeling isolated to the turning point when he received assistive technology that transformed his learning experience. He also talks about the crucial role of support from his family, particularly his mother, and his teacher who helped him believe in himself.Additional ResourcesDr. Cathy Barr's UHN Research websiteUHN Foundation story featuring Dr. Cathy Barr – "Reading the Genome"Sick Kids Empower Reading & Learning GroupLearning Disabilities Association of OntarioThe Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Experienced Licensed Clinical Psychologist with a demonstrated history of working in the health wellness and specializes working with mood, anxiety and trauma populations. Skilled in corporate wellness, family/couples counselling, negotiation, Psychological Assessments, Crisis Intervention, Self-esteem building, cognitive behavioural therapy and mindfulness meditation practices. Strong healthcare services, professional graduated from Certified Coaches Federation, UofT and worked in correctional facilities, as well as at reputable hospitals including Lakeridge mental health, CAMH and UHN. Learn more drmonicavermani.com

Neurofibromatosis, also known as NF, is one of the most common genetic disorders affecting about 1 in 3000 people globally. However, little is known about the condition causing it to often be misdiagnosed or go undiagnosed. Neurofibromatosis causes different types of tumors to form in various parts of the body.In this bonus episode, Dr. Ryan Thomas, a family physician and Clinical Associate at UHN's Elisabeth Raab Neurofibromatosis Clinic—the only adult NF clinic in Canada—shares his personal journey with NF. Diagnosed in his late twenties, Dr. Thomas underwent a life-changing surgery to remove a large tumor in his chest, just two months before his wedding. His experience provides a unique perspective on the condition, allowing him to connect deeply with his patients.Additional ResourcesCanadian First : UHN Opens Multidisciplinary Clinic on Genetic DisorderElisabeth Raab Accelerator of Science to End NeurofibromatosisNeurofibromatosis OntarioDr. Gelareh Zadeh's lab – link to more info about the Elisabeth Raab Neurofibromatosis ClinicChildren's Tumour FoundationThe Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

This episode is brought to you by Birch Living, LMNT, and Thesis. One in five people is impacted by chronic pain. Many believe that chronic pain is simply a byproduct of aging, with little that can be done beyond managing it. Today's guest offers a unique approach to chronic pain, sharing her mind-body practice for effectively addressing and alleviating it. Today on The Dhru Purohit Show, Dhru sits down with Dr. Andrea Furlan to explore chronic pain, its top drivers, and common myths about treatment. Dr. Furlan discusses the dangers of a sedentary lifestyle in exacerbating chronic pain and reveals her unique approach to treating it. She also covers how diet, sleep, and alcohol can impact chronic pain and shares the most successful interventions for addressing it. Dr. Andrea Furlan is a scientist at the Institute for Work & Health (IWH) and physician and senior scientist at the KITE Research Institute, Toronto Rehab, University Health Network(UHN). She is a Physical Medicine & Rehabilitation professor at the University of Toronto. She is chair of ECHO Ontario Chronic Pain and Opioid Stewardship at UHN and co-chair of ECHO Occupational and Environmental Medicine and ECHO for Return to Work of Public Safety Personnel at IWH. She is a physician in the pain clinic at Toronto Rehab and the author of the book 8 STEPS to Conquer Chronic Pain. A Doctor's Guide to Lifelong Relief.   In this episode, Dhru and Dr. Furlan dive into (audio version / Apple Subscriber version): Chronic vs. Acute Pain (00:00:30 / 00:00:30) Top Drivers of Chronic Pain (04:07 / 04:07) Myths About Treating Chronic Pain (08:22 / 11:35) The Dangers of a Sedentary Lifestyle (11:20 / 14:30) How to Address Chronic Lower Back Pain (21:00 / 26:17) 8 Food Rules (27:40 / 32:57) Alcohol Use and Environmental Factors (39:18 / 44:35) Supplements to Support Chronic Pain (43:30 / 48:47) Fear of Chronic Pain (53:11 / 58:28) The Most Successful Interventions (57:15 / 1:02:32) Avoiding a Sedentary Life by Activating Joy (1:00:45 / 1:06:02) Mindset Matters (1:04:30 / 1:09:47) Also mentioned in this episode: 8 Steps to Conquer Chronic Pain: A Doctor's Guide to Lifelong Relief  To learn more about Dr. Furlan, follow her on Instagram, YouTube, Facebook, X/Twitter, or her website.  This episode is brought to you by Birch Living, LMNT, and Thesis. To get 25% off your Birch Living mattress plus two free eco-rest pillows, head over to birchliving.com/dhru today. Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to DrinkLMNT.com/dhru today. Right now, Thesis is offering my community $60 off your first subscription. Just head to takethesis.com/dhru and use the code DHRU to enhance your cognitive health today.  Learn more about your ad choices. Visit megaphone.fm/adchoices

THE MEDICAL RECORD: WHAT COMES AFTER CANCER TREATMENT? Libby Znaimer is joined by Dr. Fahad Razak, a Canada Research Chair in Healthcare Data and Analytics at the University of Toronto and General Internist at Unity Health Toronto, Dr. Alisa Naiman, a family doctor practicing comprehensive primary care in Toronto, and Dr. Keith Stewart, Vice President, Cancer and Director of Princess Margaret Cancer Program at the UHN. Today: a discussion about what comes next for cancer patients who complete treatment, a new guideline in the U.S. pertaining to mammogram results and, closer to home, Ontario Health is changing its guidelines on how iron deficiency is measured. THE PAINFUL REALITY OF ONLINE TRANSACTIONS Libby Znaimer is joined by Carmi Levy, Technology Analyst and Journalist based in London, Ontario. Why is making a transaction online such a hassle whether we purchase tickets for a concert or sports match or purchase something from a retailer? There's always a tedious process to follow including registration and providing personal details and even credit card info. Why are companies doing this, and what can we do as consumers to make the process less of an inconvenience?   REACTION TO THE TRUMP-HARRIS DEBATE Libby Znaimer is now joined by Brad Polumbo, a Conservative commentator and editor-in-chief  & Co-Founder of BASEDPolitics, Dr. Chris Cooper, Political Science Professor at Western Carolina University, and Lee Strickland, Toronto Chair of Democrats Abroad. Americans and the world got to watch the first ever debate between former U.S. President Donald Trump and Vice President Kamala Harris and it ventured into the absurd at times. Our panel of Americans weighs in on what was said and whether VP Harris or former President Trump won the debate.

September 8 2024-On the Road with The Beatles & It's Arthritis Awareness Month It's been 60 years since Beatlemania gripped the world. And one man..then a reporter with the London Daily Express..spent six weeks of unrestricted access to the fab four during their iconic 1964 North American tour. In his book ‘The Beatles And Me On Tour- 60th Anniversary Edition' Ivor Davis recalls his life on the road, serving up the stories behind the stories. We reached author Ivor Davis at his home in Southern California. And Cutting-edge research is helping the over 6 million Canadians who suffer from arthritis, find some life changing relief. But, arthritis remains the leading cause of workplace disability in Canada, impacting sleep, mental health, physical activity, and more. We speak with Dr. Megan Himmel, Rheumatologist with UHN's Schroeder Arthritis Institute.

Parkinson's disease is the fastest-growing neurological condition in the world, affecting over 100,000 Canadians and 12,000 new cases diagnosed every year. In this bonus episode of Your Complex Brain, we explore the transformative power of exercise in managing Parkinson's symptoms and possibly slowing the disease's progression.Join us as we hear from Steven Iseman, who was diagnosed with Young Onset Parkinson's Disease at 48. Now 58, Steven shares his remarkably journey from hiding his diagnosis to becoming a passionate advocate for Parkinson's awareness and the benefits of exercise. Learn how he co-founded the Rigid Riders cycling club and the Spinning Wheels Tour, cycling 8,000 km across Canada to connect with and support others living with Parkinson's. Steven's story is one of resilience, community and the relentless pursuit of a better life despite his diagnosis. Discover how exercise has not only helped Steven manage his symptoms but also given him a renewed sense of purpose and direction. Additional ResourcesUHN Movement Disorders Clinic websiteKalia Labs websiteVideo: Dr. Lorraine Kalia on why she studies Parkinson'sVideo: Dr. Lorraine Kalia Discusses the Latest in Parkinson's Research on TVO's The AgendaVideo: The Rigid Riders StorySpinning Wheels Cycling TourThe Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

In this bonus episode of Your Complex Brain, we hear from John Ruffolo, Founder and Managing Partner of Maverix Private Equity, who shares his personal journey of surviving a life-threatening cycling accident in 2020 that left him with a severe spinal cord injury. John recounts the harrowing moments following the accident, his extensive surgeries, and his remarkable recovery journey. Despite being diagnosed with the most severe grading of spinal cord injury, John's relentless spirit and dedication to physical therapy have led to astonishing improvements in his mobility.Featuring: John Ruffolo is the Founder and Managing Partner of Maverix Private Equity, a private equity firm focused on technology-enabled growth and disruption investment strategies. Maverix invests in health and wellness, financial services, transportation and logistics, live, work, play and learn and retail. As an active board member in the profit and not-for-profit sectors, John works with many leading innovative organizations and has been recognized as Canada's #1 of 100 Most Powerful Business People by Canadian Business Magazine and was selected as one of Toronto's 50 Most Influential People by Toronto Life. He is currently living with a spinal cord injury.Additional ResourcesUHN's Spinal Cord Injury ClinicDr. Fehlings' Laboratory for Neural Repair and Regeneration websiteDr. Fehling's interview on Season 1 of Your Complex Brain, 'Revolutionary Advances in Spinal Cord Injury'PSI Foundation feature story on Dr. Laureen HachemToronto's Top Grad Dreams Big – Toronto.com feature story on Dr. Laureen Hachem as a high school studentThe Globe and Mail feature story on John RuffoloThe Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

In this bonus episode of Your Complex Brain, we delve into the world of dementia care with Maria Martinez, a dedicated social worker at UHN's Memory Clinic, part of the Krembil Brain Institute. With nearly 25 years of experience, Maria shares her journey from studying anthropology and sociology to becoming a vital support for patients living with dementia and their families.Maria highlights the unique challenges faced by those dealing with rare dementias and early-onset cases, emphasizing the importance of personalized support and the significant financial burdens these families often encounter.Despite the challenges, Maria finds hope and fulfillment in her work, learning continuously from the resilient families she supports. This episode offers a heartfelt glimpse into the daily efforts of a social worker dedicated to making a difference in the lives of those affected by dementia.Featuring: Maria Martinez has been a social worker for nearly 25 years. Most recently, she has worked with the team at UHN's Memory Clinic, helping patients living with Alzheimer's and dementia, and their families, navigate their diagnosis and community support.Additional resources:Dr. Carmela Tartaglia's interview on EP 1 of Your Complex Brain – ‘The Quest to Solve the Concussion Problem' Risk Factors for Alzheimer's and Dementia (video) UHN Memory Clinic Schlegel-UW Research Institute for Aging (RIA) Dr. Laura Middleton's research project - DREAM (Dementia Resources for Eating, Activity, and Meaningful Inclusion Dr. Laura Middleton's research project - DICE (Dementia Inclusive Choices for Exercise)The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Loud, disruptive snoring could be (but isn't always) a sign of sleep apnea, a common condition in which breathing may stop and start many times throughout the night. You may be aware that sleep apnea can disrupt your sleep and cause fatigue, but did you know that it can also impact your heart, your brain – even your sex drive?In today's episode, we discuss the health risks of undiagnosed sleep apnea and why, if you're having trouble sleeping or staying awake during the day, if you're experiencing morning headaches, mood changes or difficulty focusing, you should consider getting a sleep test.Featuring: Dr. Douglas Bradley - Director of UHN's Centre for Sleep Health and Research, at Toronto General Hospital.Dr. Frances Chung - Anesthesiologist and Clinician Investigator with UHN's Krembil Brain Institute; Inventor of the STOP-Bang Questionnaire, a new screening tool for sleep apnea that's being used around the world.  Carmen Chu – Fundraising professional and cancer survivor, who was recently diagnosed with sleep apnea. Additional resources: UHN's Centre for Sleep Health and ResearchDr. Frances Chung named UHN Inventor of the YearDr. Douglas Bradley featured in KITE Research spotlight: Use of non-invasive breathing device to alleviate obstructive and central sleep apnea improves quality of life The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Alley Wilson, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

At UHN's Krembil Brain Institute, we have cared for many patients living with an extreme and heartbreaking facial pain disorder called trigeminal neuralgia. Patients often describe the pain as a lightning bolt to the face, or an electric shock. Some talk about the impact the disease has had on their family & relationships, including not being able to hug their loved ones, or kiss their children goodnight. In today's episode, we discuss how AI is helping researchers look for patterns and clues to treat patients living with trigeminal neuralgia and other chronic pain disorders.Featuring: Dr. Mojgan Hodaie – Neurosurgeon and senior scientist with UHN's Krembil Brain Institute and the Greg Wilkins-Barrick Chair in International Surgery at UHN. Dr. Hodaie is also a Professor and the Postgraduate Medical Education Director for the Department of Surgery, at the University of Toronto's Temerty Faculty of Medicine. Her surgical practice and research laboratory are dedicated to unraveling the underpinnings of the severe pain condition of trigeminal neuralgia, using advanced brain imaging technology. Her interest and dedication to education spans local, national and international activities.Adriana Salazar - Graduated from The University of Western Ontario with a Bachelor of Management and Organizational Studies (BMOS) and has worked in the Finance Department at a law firm for the past 9 years. She is happily married and has a lovely daughter who just finished her first year of school.  In her off time, she enjoys traveling back home to Colombia to see her family, painting in watercolours, and reading James Patterson novels in her hammock.Additional resources: Dr. Hodaie was interviewed on Season 1 of Your Complex Brain – “The most painful brain disease you've never heard of”Toronto neurosurgeon marks 1,000th operation treating 'excruciating' facial pain syndromeDr. Hodaie recounts her journey from new immigrant to neurosurgeon (video)Brain Aging in Fast Forward (UHN Research article)Dr. Hodaie was a featured speaker at KBI's first-ever ‘International Day of Women and Girls in Science' event (video)The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

The Lullaby Project brings together expectant mothers with professional songwriters to write, record, and perform an original lullaby for their baby. In 2017, Massey Hall and Roy Thomson Hall brought this heartwarming initiative to Toronto, and invited partners to participate, including Dr. Esther Bui, a neurologist who specializes in treating women with epilepsy. Today, we're exploring whether participating in a project like The Lullaby Project can improve overall mental health for pregnant women who are living with epilepsy. Featuring: Dr. Esther Bui - Neurologist and epilepsy specialist focusing on women's neurological health; Assistant professor and clinician educator within the Division of Neurology, Department of Medicine at the University of Toronto. Dr. Bui founded Canada's first and only accredited Women's Neurology Fellowship at the University of Toronto. She is currently the co-Director of the Women's Neurology Fellowship Program and the Director of the Epilepsy Fellowship program. Sharon Ng - Graduate student in neuroepidemiology at the Harvard Chan School of Public Health. She was previously a research assistant for Dr. Esther Bui at UHN, and worked with Dr. Bui to conceptualize the Lullaby Project Study. Sharon is now a collaborator on this study.Julianne Hazlewood – CBC journalist for more than a dozen years, at newsrooms across Canada. Her true love is longform audio storytelling. Becoming a mother is the latest and most joyous chapter in her life.  Additional resources: The Lullaby Project The Lullaby Project PlaylistJulianne Hazlewood's CBC radio documentary on White Coat Black ArtDr. Esther Bui interviewed in Season 2 of Your Complex Brain podcast - A New Era in Women's Brain Health: Closing the Gap on Delayed DiagnosisAdvancing Women's Neurology through Education, Research and Advocacy (U of T story featuring Dr. Esther Bui & Dr. Aleksandra Pikula)Dr. Esther Bui featured in UHN Foundation ‘Know Your Heroes' seriesThe Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

A stroke happens when there is a sudden blockage of blood flow to the brain or bleeding in the brain, which can result in symptoms such as numbness or weakness, trouble speaking, confusion, or dizziness. The type of symptoms one might experience depends largely on the type of stroke, and the area of the brain affected. But one thing is clear – despite the many advances in stroke care over the past 30 years, it's women who often suffer the most.  In today's episode, we discuss why women are more susceptible to stroke, what the unique risk factors are, and what women need more of to help them recover, not only from the medical condition, but the impacts to their careers, their mental health and their families. Featuring: Dr. Aleksandra Pikula, MD, PhD, is a neurologist and clinician-investigator at UHN's Krembil Brain Institute and the newly appointed Jay and Sari Sonshine Chair in Stroke Prevention and Cerebrovascular Brain Health at UHN. Dr. Pikula advocates for a holistic approach to brain care, specifically targeting stroke and dementia prevention during midlife through evidence-based lifestyle medicine pillars.Patrice Lindsay, PhD, is currently the Lead for the People With Lived Experience (PWLE) Engagement and Stroke Strategy at the Heart and Stroke Foundation of Canada. Dr. Lindsay leads strategic directions for health systems design and change for people with stroke and heart conditions across Canada and internationally. Shruti Kothari is an actress born, raised, and residing in Toronto. Her career was focused largely on Shakespeare and Musical Theatre until her life took an unexpected turn when she suffered a life-altering brain hemorrhage and stroke at the age of 30. Over the past four years, Shruti has focused on reshaping her life and raising awareness about brain injuries in younger people. Additional resources: UHN's Stroke Prevention ClinicDr. Pikula interviewed in the Your Complex Brain episode “The Rise of Stroke in Young Adults”UHN Foundation video “Shruti's journey back to the stage, with some help from Team UHN”Heart and Stroke Foundation of Canada – Women's Digital HubWorld Stroke Academy pThe Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Do you know a child who has difficulty spelling or sounding out words? Maybe they feel stressed or anxious when it comes to reading, or they try to avoid it altogether?These symptoms could be a sign of a reading disorder, which is the most common form of a learning disability.In this episode, we discuss the prevalence and impact of reading disorders, what scientists are learning about the genetic links, and what that could mean for new approaches and treatments in the future.Featuring: Dr. Cathy Barr – Senior Scientist with UHN's Krembil Brain Institute and the Hospital for Sick Children. Her research focuses on genetic links to neurodevelopmental disorders, such as childhood depression, Tourette's syndrome, ADHD and reading disabilities. Dr. Barr's team has identified genes that may contribute to these disorders. They're now focusing on understanding how those changes in DNA could influence genes, and contribute to risk.Dr. Maureen Lovett – Senior Scientist Emeritus in Neurosciences and Mental Health at The Hospital for Sick Children, where she founded and directed the hospital's Learning Disabilities Research Program for more than 35 years. Since 2020, Dr. Lovett has served as Associate Director of the Haskins Global Literacy Hub at Yale University and the University of Connecticut.Matthew Cote – Teacher and advocate for those living with learning disabilities, including reading disabilities. Matthew has lived experience with learning disabilities.Additional resources: Dr. Cathy Barr's UHN Research websiteUHN Foundation story featuring Dr. Cathy Barr – “Reading the Genome”Sick Kids Empower Reading & Learning GroupLearning Disabilities Association of OntarioThe Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Have you ever heard of a genetic condition called neurofibromatosis, also known as NF?It's one of the most common genetic disorders, affecting about 1 in 3000 people globally. NF causes different types of tumours to form in various parts of the body. Because so little is known about the condition, it's often misdiagnosed, or not diagnosed at all. UHN is home to the Elisabeth Raab Neurofibromatosis Clinic, the only adult NF clinic in Canada. We discuss the clinic and the exciting research happening in the field of NF. But, for many people living with the condition, the stigma is often as challenging as the illness. Featuring: Dr. Suganth Suppiah – Surgeon-scientist at UHN's Krembil Brain Institute and Assistant Professor at the University of Toronto. Dr. Suppiah also leads the nerve surgery program at the Elisabeth Raab Neurofibromatosis Clinic, Canada's only adult NF clinic, based at UHN.Dr. Ryan Thomas – Family physician and Clinical Associate who works with patients at the Elisabeth Raab Neurofibromatosis Clinic. Dr. Thomas lives with neurofibromatosis himself.Additional resources: Canadian first: UHN Opens Multidisciplinary Clinic on Genetic DisorderElisabeth Raab Accelerator of Science to End NeurofibromatosisNeurofibromatosis Ontario Dr. Gelareh Zadeh's lab – link to more info about the Elisabeth Raab Neurofibromatosis ClinicChildren's Tumour FoundationThe Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Parkinson's disease is the fast-growing neurological condition in the world. In Canada, more than 100,000 people are currently living with Parkinson's and 12,000 new cases are diagnosed every year. In this episode of Your Complex Brain, we discuss the latest science surrounding the benefits of exercise for Parkinson's, including whether exercise can alleviate some of the symptoms of Parkinson's or slow the progression of the disease.Featuring: Dr. Lorraine Kalia is a Neurologist & Senior Scientist at UHN's Krembil Brain Institute and the Wolfond-Krembil Chair in Parkinson's Disease Research at UHN. She is also an Associate Professor at the University of Toronto.Steve Iseman is currently living with Parkinson's. He is co-founder of the ‘Rigid Riders,' a Toronto-based cycling group for people living with Parkinson's, and an avid cyclist & skier.Additional resources: UHN Movement Disorders Clinic websiteKalia Labs websiteDr. Lorraine Kalia on why she studies Parkinson's (video) The Rigid Riders Story (video)Spinning Wheels Cycling Tour The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

This episode features Darlene Dasent, Executive Vice President & Chief Financial Officer at University Health Network. Here, she shares key insights into UHN, accomplishments UHN has achieved that she is proud of, her focus on the impact of rapidly evolving technology, and more.

In 1995, actor Christopher Reeve was injured in a horseback riding accident, leaving him quadriplegic - paralyzed from the shoulders down. He became a tireless advocate and a passionate supporter of research. Christopher's dream was for those living with spinal cord injuries to have a better quality of life, and one day to walk again. More than 25 years later, thanks to advances in surgical approaches, neuroprotective drugs, and gene therapy using stem cells, that dream is becoming closer to reality.Featuring: Dr. Laureen Hachem is a Senior Neurosurgery Resident and PhD Candidate at UHN's Krembil Brain Institute and the University of Toronto. Dr. Michael Fehlings is a Neurosurgeon and Senior Scientist at UHN's Krembil Brain Institute and a Professor of Neurosurgery at the University of Toronto. Dr. Fehlings also holds the Campeau-Tator Chair in Brain and Spinal Cord Research at UHN.John Ruffolo is the Founder and Managing Partner of Maverix Private Equity, a private equity firm focused on technology-enabled growth and disruption investment strategies. He is currently living with a spinal cord injury.Additional resources: UHN's Spinal Cord Injury ClinicDr. Fehlings' Laboratory for Neural Repair and Regeneration websiteDr. Fehlings interview on Season 1 of Your Complex Brain, ‘Revolutionary Advances in Spinal Cord InjuryPSI Foundation feature story on Dr. Laureen HachemToronto's Top Grad Dreams Big – Toronto.com feature story on Dr. Laureen Hachem as a high school studentThe Globe and Mail feature story on John RuffoloThe Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

In the time that it takes to say this sentence – three seconds – someone in the world will develop dementia, a group of symptoms impacting memory, thinking, mood, behaviour and the ability to complete everyday tasks. Alzheimer's is the most common form of dementia.With people living longer, even into their 90s and beyond, dementia is becoming the biggest and most consequential global health threat of our time. But, according to a landmark study in The Lancet medical journal, there are 12 modifiable risk factors that can reduce your chances of getting dementia at any age – by up to 40%. In this episode of Your Complex Brain, we discuss which of those risk factors are most impactful to lower – or even reverse – your risk of dementia, with a focus on the latest science looking at the benefits of exercise.Featuring: Maria Martinez has been a social worker nearly 25 years. Most recently, she has worked with the team at UHN's Memory Clinic, helping patients living with Alzheimer's and dementia, and their families, navigate their diagnosis and community supports.Dr. Carmela Tartaglia is a Neurologist and a Clinician Scientist with UHN's Krembil Brain Institute, as well as co-Director of UHN's Memory Clinic and an Associate Professor at the University of Toronto.Dr. Laura Middleton is an associate professor and the Schlegel Research Chair in Dementia and Active Living, at the University of Waterloo. She is also an Affiliate Scientist at KITE, the research arm of UHN's Toronto Rehabilitation Institute. Additional resources: Dr. Carmela Tartaglia's interview on EP 1 of Your Complex Brain – ‘The Quest to Solve the Concussion Problem'Risk Factors for Alzheimer's and Dementia (video)UHN Memory ClinicSchlegel-UW Research Institute for Aging (RIA)Dr. Laura Middleton's research project - DREAM (Dementia Resources for Eating, Activity, and Meaningful InclusionDr. Laura Middleton's research project - DICE (Dementia Inclusive Choices for Exercise)The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

In a sweeping 2023 report, the US Surgeon General, Vivek Murthy, declared loneliness an epidemic and a public health emergency. According to the report, loneliness and isolation can lead to a significant increase in mental health disorders, such as anxiety and depression, as well as a nearly 30% increased risk of heart disease, stroke and among older adults, a 50% risk of dementia.Around the world, there are efforts to help people cope with loneliness. In the Netherlands, one grocery store chain has introduced ‘chat check outs' where customers can take their time and socialize – part of a government initiative to address the growing issue of isolation.There are also a number of apps to help introduce you to your neighbours anywhere you live in the world.And a recent story in The Globe and Mail profiled a woman who rents her time out to those needing a dinner companion, a study buddy, or a listening ear. She's seen more than 60 clients so far. Today's episode focuses on the health impact of loneliness on the brain, why social media seems to be making us lonelier even as it's meant to connect us, and how each of us can learn to exercise our social muscle, and improve our overall health.Featuring: Dr. Jaideep Bains – Director of the Krembil Research Institute at UHN and co-Director and Senior Scientist with UHN's Krembil Brain Institute. Dr. Hayley Hamilton – Associate Director and Senior Scientist with the Institute for Mental Health Policy Research at the Centre for Addiction and Mental Health (CAMH).Additional resources: UHN's Krembil Brain InstituteDr. Jaideep Bains' public talk – ‘Is My Stress Your Stress?' The Centre for Addiction and Mental Health (CAMH)The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

We are once again bringing you inside UHN's Krembil Brain Institute, one of North America's largest and most innovative neurological centres, to meet the scientists & physicians advancing discovery, the patients who inspire us, and the care teams who support them. This season, we're exploring some big new research in brain health, including: What young women need to know about preventing a stroke, Can loneliness re-wire your brain? And how YOU can reduce YOUR chances of Alzheimer's. We'll also take you to the forefront of AI powered brain science, dive into the link between genetics and reading disabilities  and find out why getting a good night's sleep is crucial for brain health.There are a million amazing things to know about your complex brain – and we couldn't be more excited to explore them with you. Season 3 launches March 19, with episodes every other Tuesday. Subscribe to Your Complex Brain so you don't miss a thing.The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhn.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Breathing exercises are simple techniques can help improve your overall well-being by promoting relaxation, reducing stress, and increasing mindfulness. Listen to this original 5-minute 'Breathing Space' practice created by Dr. Kathryn Curtis for listeners of Your Complex Brain.Dr. Kathryn Curtis is a clinical psychologist at the Comprehensive Integrated Pain Program at UHN, where she provides psychological services to individuals living with chronic pain. Dr. Curtis' research evaluates mind-body interventions, such as yoga and mindfulness, for populations experiencing chronic pain and mobility restrictions. She is a long-term student of eastern philosophy, meditation, and Vedic studies at Vidya Institute and integrating these eastern teachings into her clinical and research work is a passion of hers. In her spare time, Dr. Curtis enjoys spending time in nature with her family.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Harry Forestell is a journalist with CBC Television. In 2013, he noticed a tremor in his right hand and was unsure what it was. It was later determined to be Parkinson's disease. He was referred to Dr. Tony Lang and the team at Toronto Western Hospital, a movement disorder clinic. They confirmed the diagnosis and began treatment. The symptoms of the disease began to worsen, and he was frustrated by the amount of focus and attention it took to walk normally. His doctor suggested deep brain stimulation (DBS) as a potential treatment option. He was hesitant at first, but as the symptoms worsened, he decided to explore the option further. He spent a weekend in November going through a series of tasks to see if he would be a good candidate for DBS. He was delighted to pass and was excited about the prospect of another treatment option. He spent a month in Toronto having the procedure done and was impressed by how quickly and with little fuss the surgery was completed. He was back at work and was able to return to his regular social life and work obligations. The impact of the DBS was immediate and very pleasing. His tremors and shakes abated, and he didn't have to experience dyskinesia anymore. He was able to return to work and even appear on camera, which was a huge bonus for him.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Fran Ryder is the president of the Ontario Women's Hockey Association and has been involved in women's hockey for many years. She has played and volunteered in various capacities in the sport. She has also been involved in research and initiatives related to spinal injuries and concussions in hockey, working closely with Dr. Charles Tator, a world-renowned neurosurgeon and researcher, on these initiatives. Dr. Tator has been a mentor and inspiration to her. She has also been a champion of the importance of brain donations for research and has donated her brain to Dr. Tator's research. She is passionate about the sport and the importance of safety and prevention of injuries in addition to advocating for the recognition and treatment of concussions and other brain injuries in sports.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Natalie Ladly is the president and fundraising chair for CDKL5 Canada. She lives in Heathcoate, a town outside of Collingwood, Ontario, with her husband Eric and their three children: Brynn, Reece, and Cullen. Brynn has CDD, a rare disease that prevents the brain from developing normally. She was diagnosed with the disease at nine months old, and since then, Natalie has been dedicated to raising awareness and funds for research. Natalie is also a member of the CDKL5 Canada board, which gives her a sense of purpose and the ability to make a difference. Natalie is grateful for the support of Dr. Eubanks, a scientist who is dedicated to researching CDD and making a real impact in the lives of those affected by the disease. She believes that collaboration between the scientific community and patient advocacy groups is crucial for rare diseases, as it allows for a more holistic approach to treatment and care. Overall, Brynn's journey with CDD has taught Natalie to take things one day at a time and to cherish the silver linings in life.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Dr. Amin Madani is the director of the Surgical AI Research Academy (SARA) at the University Health Network (UHN). He is an endocrine and acute care surgeon at UHN and assistant professor of surgery at the University of Toronto. Dr. Madani talked to us and showed us some of the work he is doing on AI in surgery and in particular on computer vision. He really breaks down for us the terms AI, machine learning, and data science, and highlighted some of the promise and challenges for AI in surgery. Email Dr. Madani: amin.madani@uhn.ca Watch full unedited interview on YouTube: https://youtu.be/aawdQy90v2Q Links: 1. https://temertysimcentre.com/surgical-artificial-intelligence-research-academy-sara/ 2. Video of Go No Go: https://www.youtube.com/watch?v=MmcW8JK1Qv4 3. Surgical Data Science: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135051/ 4. Artificial Intelligence for Intraoperative Guidance: Using Semantic Segmentation to Identify Surgical Anatomy During Laparoscopic Cholecystectomy. https://pubmed.ncbi.nlm.nih.gov/33196488/

Jack Conway, a 19-year-old from Toronto, Canada, is a huge fan of video games and roller coasters. His family includes his mom, Kim, his dad, Steve, and his older brother, Brian. Jack plays a variety of video games, from Call of Duty to Minecraft, and he loves roller coasters. He also has a vision impairment due to a brain tumor he had when he was a baby. He was one of the first children in the world to receive a certain treatment for the tumor, and he spent a lot of time at SickKids hospital. School can be challenging for him because of his vision, but he tries not to let it get the better of him.He has done a vision study using virtual reality goggles, and it has improved his vision and quality of life. He is excited about the potential for technology to restore vision and is happy to have been accepted into all six college programs he applied for.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Lindsay's mother Barbara had Alzheimer's disease. Lindsay, her brothers, and her father noticed changes in her mid-sixties. They started noticing her repeating herself and she stopped coming to the pool with them when they went to visit her and their dad in Florida. She also forgot where she parked her car and had to ask for help. Her memory was not what it used to be and she started to withdraw from social events.Lindsay and her brothers decided they needed to talk to her doctor about these memory issues. They decided as a family that it was time to look into homes for her. They did not want to wait until it was an emergency and they had to put her into a home. They found a home that was dedicated to people with dementia and they were able to get her a room there. It was a very hard decision for Lindsay and her family. They had to depend on each other to take care of her. Lindsay visited her every day and she felt like she was doing this for herself as well. It was very hard for Lindsay to see her mother like this. She missed being able to call her and tell her about her life. She wished her mother could see her kids grow up and experience life without her.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Lara Pingue shares her story about living with chronic back pain and the challenges of getting a diagnosis and finding effective treatment. She describes the initial onset of her pain and the various treatments she tried, including physical therapy, chiropractic care, and prescription medications. She also discusses the impact of the pain on her daily life and the frustration of not being able to find a lasting solution. Eventually, she decided to pursue surgery and was able to get a referral from her doctor. The surgery was not without complications, but it did provide some relief from her pain. Since then, she has focused on managing her pain through a combination of movement and over-the-counter pain medication. She emphasizes the importance of believing people with chronic pain and destigmatizing treatment for it.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

As a child, Nikki experienced seizures that she did not realize were seizures. She would feel "other" and disconnected from the world. Her earliest seizure memory is from when she was six years old, triggered by looking out the window of her parent's house. She would sometimes go to the window to see if she would have a seizure.Today, her seizures are still the same as when she was a child. They last about a minute and are triggered by being outside. They start with a warming sensation in her lower abdomen and a feeling of over-familiarity. Then, she gets a radiating heat and nausea, which makes her cough. She then feels like she is being taken up a roller coaster and dropped. She can calculate how many seconds she has left in the seizure based on where the heat is in her body. After the seizure, she is fatigued but not confused. She accepts the differences in her body and does not let them affect her daily life. She is grateful to not have to deal with the struggles that other people with epilepsy face. Having focal aware seizures has allowed her to learn more about herself and her brain.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Farrah Schwartz is the manager of Patient Education and Engagement at UHN. Her work entails assisting patients in actively participating in their care and improving organizational processes. The Patient Education and Engagement program provides resources, training, and coaching to help Team UHN engage patients in their care. They are also working on patient engagement within organizational improvement and partnering with equity-seeking groups to ensure that health information is inclusive and non-stigmatizing.Farrah has experienced stress throughout her life, including during the pandemic. She had a laser focus on her work and was able to channel her stress into something productive. Stress comes in many forms, and it is important to recognize and manage it. Farrah recommends tuning into your mood, practicing self-compassion, and finding gratitude in small things. She has learned that it is not possible to do everything and that it is important to set realistic expectations.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

In the second season of Your Complex Brain, join us on a thrilling journey as we delve into the boundless realm of neuroscience, brain health, and ground-breaking research and its impact on our lives. Through thought-provoking discussions, expert interviews, and captivating patient stories, we unravel the mysteries of our brain.The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

From new Alzheimer's drugs, to novel treatments for brain cancer, to chronic pain, many of us feel overwhelmed by the sheer volume of health news in the media and confused about what to believe - and how it applies to our own health.In this special episode of Your Complex Brain - our last of the season - we bring back five of our featured UHN brain experts to weigh in on the top, science-based, evidence-backed tips for keeping your brain fit and healthy as you age (and some of their answers may surprise you!)Host Heather Sherman also introduces the Your Complex Brain production team and asks what they each do to keep their brains happy and healthy.Featuring: Drs. Andrea Furlan, Jaideep Bains, Mary Pat McAndrews, Donald Weaver and Aleksandra Pikula.  Additional resources (5-6): Dr. Andrea Furlan's YouTube Channel Dr. Jaideep Bains' public talk – ‘Is My Stress Your Stress?' Dr. Mary Pat McAndrews' discussing her science journey & why she studies memory Dr. Donald Weaver's Your Complex Brain Season 1 podcast episode – ‘What's it Going to Take to Solve Alzheimer's?' Dr. Aleksandra Pikula's Your Complex Brain Season 1 podcast episode – ‘The Rise of Stroke in Young Adults' The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

More than eight million Canadians are currently living with the effects of debilitating chronic pain.In this episode, we discuss the connection between chronic pain and the brain, including the latest & most effective treatments, the stigma - how do you study and treat something that you often can't see? And, is there a way to build ‘pain resilience'?We'll speak with Dr. Andrea Furlan, a senior scientist & physiatrist with the KITE Research Institute and Dr. Anuj Bhatia, an anesthesiologist and clinician investigator with the Krembil Brain Institute.We'll also hear from Lara Pingue, about her personal experience living with chronic pain.Featuring: Dr. Anuj Bhatia - Anesthesiologist and pain medicine physician who is the Director of the Comprehensive Integrated Pain Program at UHN, a clinician investigator with the Krembil Brain Institute, and a Professor at the University of Toronto.Dr. Andrea Furlan - Senior Scientist at The KITE Research Institute and a physiatrist with the Toronto Rehabilitation Institute, at UHN. Lara Pingue - Editor for the Globe and Mail. She lives with her husband and children in Toronto.Additional resources:Comprehensive Integrated Pain Program at UHN‘The Krembil Brain Institute's chronic pain experts are using novel treatment approaches – and returning people to meaningful lives' – Article in 2021 KBI Magazine, featuring Drs. Anuj Bhatia & Hance ClarkeDr. Andrea Furlan's KITE Research Institute pageDr. Andrea Furlan's Youtube ChannelDr. Andrea Furlan interviewed on UHN's ‘Behind the Breakthrough' podcastThe Krembil Brain Institute's ‘Your Complex Brain' podcast episode about Trigeminal Neuralgia – ‘The Most Painful Brain Disease You've Never Heard Of' featuring Dr. Mojgan HodaieThe Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

When Brynn Ladley was born, she was a smiling, happy and healthy baby, hitting all of her developmental milestones. Then, at six weeks old, she began having seizures and eventually was diagnosed with CDKL5, a rare and debilitating genetic disorder that has no cure. Upon Brynn's diagnosis, her mother Natalie became an advocate and connected with Dr. James Eubanks, a Senior Scientist at the Krembil Brain Institute, who has made it his life's mission to pioneer advanced research looking at how brain function is altered in specific rare, neurodevelopmental conditions, such as CDKL5 and Rett SyndromeHe is also developing new therapeutic strategies to better treat, or one day even cure, these diseases. We'll also hear from Brynn's mother Natalie and from Richard Logan, Dr. Eubanks' long-time lab manager, who are optimistic about advances in this research, in the years to come.Featuring: Dr. James Eubanks – Senior Scientist and Research Division Head at the Krembil Brain Institute, part of UHN.Natalie Ladly – President of CDKL5 Canada and mother to seven year-old Brynn Ladly, who is living with CDKL5.Richard Logan - Lab manager and senior technologist for Dr. Eubanks' lab at the Krembil Brain Institute.Additional resources: CDKL5 CanadaOntario Rett Syndrome AssociationKrembil Brain Institute magazine article featuring Dr. EubanksUHN Foundation's ‘Know Your Heroes' article featuring Dr. EubanksCollingwood Today article about Bryn Ladley & her familyCanadian Organization for Rare Disorders The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Every year, 40 million people worldwide sustain a concussion – a type of traumatic brain injury caused by a hit or jolt to the head.We often hear about concussions in the context of sports, but most occur as a result of everyday life, from running or biking, accidental falls and motor vehicle accidents.While the vast majority of those who suffer a concussion recover in time, there are many who experience lasting symptoms. Researchers and clinicians want to know why - including Dr. Charles Tator, who's made it his life's mission to educate the public and the healthcare community about the impact of concussion, and to advocate for change in youth and professional sports.In this episode, we speak with Dr. Tator, a neurosurgeon and researcher at the Krembil Brain Institute, and Fran Rider, an athlete and a leader in women's hockey. Featuring: Dr. Charles Tator - Neurosurgeon and researcher with the Krembil Brain Institute, as well Director of the Canadian Concussion Centre, at UHN. Fran Rider – Co-founder, President and CEO of the Ontario Women's Hockey Association. Additional resources: Canadian Concussion Centre (CCC)The Hull-Ellis Concussion and Research Clinic at UHNCCC Concussion Safety Webinar Series‘The Quest to Solve the Concussion Problem' – Your Complex Brain podcast featuring Dr. Carmela TartagliaToronto Star article – “Four high-profile Canadians to donate their brains for research into concussion effects in women”The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

When you think about your favourite memories, what comes to mind?Is it the championship win at your high school football game? Your child's first words? Or the lyrics to a song you loved? In this episode, our experts tackle the big & thought-provoking questions, such as: How does our brain log & store memories? Where do memories go as we age? And why do we remember some things, and not others? Most importantly, are there any proven methods or tactics to help improve memory? The episode features neuropsychologists Dr. Mary Pat McAndrews and Dr. David Gold, as well as Dr. Samantha Audrain, a Postdoctoral fellow & trainee graduate from Dr. McAndrews' lab.Featuring: Dr. Mary Pat McAndrews - Clinical neuropsychologist and senior scientist at the Krembil Brain Institute. She is also Division Head of Clinical and Computational Neuroscience at UHN. Dr. McAndrews' work focuses on investigating memory and language in patients with memory disorders, including epilepsy and Alzheimer's disease. Dr. David Gold - Neuropsychologist and clinician investigator with the Krembil Brain Institute. Dr. Gold primarily works with patients living with epilepsy and also regularly consults with UHN's Memory and Neurosurgery clinics, as well as the Canadian Concussion Centre. Dr. Samantha Audrain - Postdoctoral fellow at the National Institute of Mental Health, and a former graduate student of the University of Toronto and UHN. Her research focuses on understanding how long-term memories are formed and stored in the brain and how that process is disrupted in patients experiencing memory dysfunction.Additional resources: UHN Neuropsychology ClinicUHN Memory ClinicUHN News story – ‘How to make a memory'How being curious led Dr. Mary Pat McAndrews to a career in scienceInt'l Day of Women and Girls in Science event - Dr. Mary Pat McAndrews presents about her research into memory (@23:40)ECHOEpilepsy series – Dr. David GoldThe Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

What happens when a vision researcher has a chance meeting with a pediatric oncologist and that collaboration leads to unexpected and promising results?In Episode 5 of Your Complex Brain, we're talking about a homegrown vision rehabilitation program helping young brain cancer survivors, whose sight has been impacted by their tumours, improve their vision.The program, developed at University Health Network in Toronto, uses virtual reality to effectively retrain parts of the brain, allowing them to better perceive objects and obstacles.Joining us on the podcast today is neurobiologist, Dr. Michael Reber, and pediatric oncologist, Dr. Eric Bouffet. We'll also hear from 18 year-old Jack Conway, one of the research participants in the study.Featuring: Dr. Michael Reber - Senior Scientist at the Donald K. Johnson Eye Institute, part of the Krembil Research Institute, at University Health Network, and Associate Professor in the Department of Ophthalmology and Vision Sciences at the University of Toronto.Dr. Eric Bouffet - Past director of the Pediatric Neuro-Oncology program at the Hospital for Sick Children in Toronto, and the first Garron Family Chair in Childhood Cancer Research.Jack Conway - High school student who is passionate about video games, theme parks, and politics. Jack was diagnosed with an optic pathway glioma brain tumour as an infant, and recently was a research participant in the Vision Rehab Study.Additional resources: Donald K. Johnson Eye Institute at UHNDr. Reber's lab websiteThe Hospital for Sick ChildrenUHN Foundation story on this Vision Rehab StudyDr. Reber interviewed on UHN's ‘Behind the Breakthrough' podcastDr. Bouffet addresses United NationsThe Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Whether as a patient, a caregiver, a neighbour or a friend, chances are, one day, we will all be touched by Alzheimer's or dementia. This disease steals our memories and cruelly robs us of our loved ones, often when we need them the most. But, there is hope and momentum in the world of Alzheimer's research. In fact, a new theory suggests that Alzheimer's could even be an autoimmune disease. In this episode of Your Complex Brain, we speak with Dr. Donald Weaver and Dr. Saskia Sivananthan. We'll also hear from Lindsay Bongard-Batori, who lost her mother Barbara to Alzheimer's. Featuring: Dr. Donald Weaver – Neurologist, medicinal chemist & Senior Scientist with the Krembil Brain Institute at UHN. Dr. Weaver is an internationally recognized research leader in university-based drug design and discovery for neurological disorders. Dr. Saskia Sivananthan – Neuroscientist & Chief Science and Knowledge Translation Officer at the Alzheimer Society of Canada, overseeing the Alzheimer Society Research Program, a dementia research priority setting leader. Lindsay Bongard-Batori - Lost her beloved mother Barbara to Alzheimer's in 2020, and hopes her story will help others caring for their loved ones.Additional resources: Dr. Donald Weaver's lab websiteUHN – Dementia & Neurodegenerative DisordersAlzheimer Society of Canada (for information on latest research awards, patient stories, help for caregivers, provincial chapters)Alzheimer Society of Canada HotlineLandmark Study: Navigating the Path Forward for Dementia in Canada(VIDEO) A New Theory of Alzheimer's (featuring Dr. Weaver)(VIDEO) Living with Dementia: A Caregiver's Perspective(VIDEO) Risk Factors for Alzheimer's and Dementia(PODCAST) What is it Going to Take to Cure Alzheimer's (featuring Dr. Weaver + Patty Kim)The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Deep brain stimulation (DBS) is complex brain surgery in which electrodes are placed at strategic, predetermined targets within a patient's brain. The electrodes are then connected to a battery pack which is surgically inserted under the skin of the chest, like a pacemaker.When DBS was first introduced as a treatment option for people living with Parkinson's disease more than 20 years ago, it was a game changer.In this episode of Your Complex Brain, we'll speak with Krembil Brain Institute neurosurgeon, Dr. Suneil Kalia, and neurologist, Dr. Alfonso Fasano, about the future of DBS – and how it could be used to help many more patients improve their quality of life, including those living with other neurological diseases.We'll also hear from CBC journalist Harry Forestell about his DBS journey.Featuring: Dr. Suneil Kalia – Neurosurgeon & Senior Scientist at the Krembil Brain Institute & Associate Professor in the Division of Neurosurgery, Department of Surgery, University of Toronto. As a stereotactic and functional neurosurgeon, Dr. Kalia focuses on the surgical management of movement disorders, epilepsy and pain. He holds the R.R. Tasker Chair in Stereotactic and Functional Neurosurgery.Dr. Alfonso Fasano – Neurologist & Clinician Investigator with the Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, at the Krembil Brain Institute (Toronto Western Hospital). Dr. Fasano is a Professor of Medicine, Department of Neurology, at the University of Toronto. He holds the Chair in Neuromodulation at UHN. Harry Forestell – Long-time CBC journalist who has reported on some of the biggest stories of our time, and is the current host of CBC News New Brunswick at 6. At the age of 53, Harry was diagnosed with Parkinson's disease and subsequently had DBS surgery. Harry is first and foremost a family man; he is married to Jennifer and they have two beautiful daughters.Additional resources: Krembil Brain Institute's Movement Disorders Clinic (Toronto Western Hospital)Krembil Brain Institute's DBS Surgery Information PageCBC story about Harry Forestell's DBS experience & surgeryVIDEO – Harry Forestell story ‘See the instantaneous effects of DBS for Parkinson's'CBC story about DBS featuring Drs. Kalia & FasanoThe Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!

Women make up nearly half of the world's population and have higher rates of neurological disorders, yet there is still a gap when it comes to better understanding and treating women living with brain-related illnesses. Many women also face systemic barriers and biases when they seek help, often leading to a delay in diagnosis and treatment.Featuring: Dr. Esther Bui - Neurologist and clinician educator at UHN's Krembil Brain Institute and assistant professor at the University of Toronto. Her research includes the creation of Canada's first accredited Women's Neurology Clinic and training program.  Find her on Twitter: @womensneurologyDr. Mary Angela O'Neal - Director of the Women's Neurology program at the Brigham and Women's Hospital in Boston, and an assistant professor of neurology at Harvard University. Dr. O'Neal also directs a Harvard Medical School course in Women's Neurology and Psychiatry.Nikki Ashworth – Experiencing seizures since she was a child, Nikki was only diagnosed with temporal lobe epilepsy in her 30s. Her seizures may come without warning, but she's been turning her experience into an art form with her dark and honest unintentional comedy. Find Nikki on IG: @strange_missRoshan Malhan - A second-year medical student at the University of Toronto's Temerty Faculty of Medicine, where he acts as a co-director for the Anesthesia Interest Group and Emergency Medicine Interest Group. He is currently exploring his interests in a number of medical specialties and looking forward to gaining additional insights during clerkship. Additional resources: UHN Epilepsy ClinicUHN Foundation ‘Know Your Heroes' Q&A with Dr. BuiCanadian Leader in Neurology: Dr. BuiBrigham and Women's Hospital Women's Neurology ProgramWomen's Health in Neurology – Dr. O'Neal (video)The Lullaby Project (Massey Hall & Roy Thomson Hall)“My epileptic seizures can hurt my pregnancy. I wrote a lullaby to soothe my baby and my fears” Julianne Hazlewood – CBC (podcast)The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembilTo get in touch, email us at krembil@uhnresearch.ca or message us on social media:Instagram - @krembilresearchTwitter - @KBI_UHNFacebook - https://www.facebook.com/KrembilBrainInstituteThanks for listening!