Podcasts about The Proms

On this week of the MalloryBros Podcast, the Bros start a little different by diving head first into topics starting with the SINNERS 2 Tom Cruise Buzz going around, They talk about their favorite FILMS with TWIST ENDINGS. Terrell poses a ONE GOTTA GO: Pizza, Wings, Burgers or Fries. They talk about PROM getting crazy pricey and clout searching and that conversation leads to the viral REDDIT question about prioritizing Kids Events over your partner. The Bros get into a small debate about this. Finally the Bros, dive into the viral "Accountability and Programming" clip from Deante Kyle of the Grits & Eggs Podcast and talk about the difference between accountability, pandering, and how Podcasting or public speaking specifically can blur messages and unintentionally cause chaos.   FOLLOW @MALLORYBROS9 on Twitter for all MalloryBros. Updates! TAP IN WITH THE REALEST 9 ON PATREON TODAY AND CATCH UP WITH OUR LATEST CONTENT! www.patreon.com/mallorybros

It’s that time of year. Graduation! Commencement! These events mark the end of a student’s academic journey, and hopefully the start of something new. These rites of passage serve as important celebrations in a young person's life. Today, we talk to those responsible for making sure these ceremonies go off without a hitch! Social media, AI and other technologies have transformed how these milestones are captured and organized. Attitudes around all this pomp and circumstance are changing too. We’ll also hear about Connecticut’s Queer Prom. GUESTS: Kristen Record: Physics teacher at Bunnell High School in Stratford, Connecticut and Senior Class Advisor Patrick Dilger: Director of Integrated Communications and Marketing Southern Connecticut State University Brayden Ransom: Community Impact Manager, The Health Collective Support the show: http://wnpr.org/donateSee omnystudio.com/listener for privacy information.

In this week's Regional Roundup, we speak to Durango's new mayor, who has made history as the first Indigenous person to hold the position. We also hear about Aspen's queer prom that offers a safe and celebratory space for LGBTQ youth. Next is a story about a choir that uses choral music to spark important community conversations. Then, we tag along on a field trip with some elementary students as they explore the Valley Floor near Telluride. And finally, we hear from the author of "Her Place on the Map: 18 Women and the Colorado Wonders Named for Them."

My first impression of Critical Role's Daggerheart RPG is that it's definitely made for the DnD 5e crowd... there is ZERO question about that. Weirdly, Wizards of the Coast even congratulated this Dungeons & Dragons competitor publicly. Watch this podcast episode on YouTube and all major podcast hosts including Spotify. CLOWNFISH TV is an independent, opinionated news and commentary podcast that covers Entertainment and Tech from a consumer's point of view. We talk about Gaming, Comics, Anime, TV, Movies, Animation and more. Hosted by Kneon and Geeky Sparkles. D/REZZED News covers Pixels, Pop Culture, and the Paranormal! We're an independent, opinionated entertainment news blog covering Video Games, Tech, Comics, Movies, Anime, High Strangeness, and more. As part of Clownfish TV, we strive to be balanced, based, and apolitical. Get more news, views and reviews on Clownfish TV News - https://news.clownfishtv.com/ On YouTube - https://www.youtube.com/c/ClownfishTV On Spotify - https://open.spotify.com/show/4Tu83D1NcCmh7K1zHIedvg On Apple Podcasts - https://podcasts.apple.com/us/podcast/clownfish-tv-audio-edition/id1726838629

Sound the klaxon - it's a national treasure alert!This week we are honoured to be joined by internationally celebrated Mezzo-soprano Dame Sarah Connolly.Dame Sarah has had an incredible career to date with standout performances including Giulio Cesare at Glyndebourne , multiple roles at the Met, the Royal Opera House, La Scala, Paris Opera and, of course Admiral Nelson in full naval regalia at the Last Night of the Proms.Dame Sarah's 24/25 season includes playing Auntie in WNO's new production of Peter Grimes and Dido in Dido and Aeneas at Amsterdam's Concertgebouw.We are hugely grateful to Dan Hartland at the Cheltenham Festival for setting up this chat - Sarah will be performing Brahms' Alto Rhapsody at the festival on 5 July (ticket link below)With such a stellar career and a vast list of honours to her name, Dame Sarah remains incredibly warm and down-to-earth. We chat about controlling performance anxiety, how to avoid being pigeon holed, dealing with colds, auditioning, the power of positive thinking and how to wear a fatsuit…Enjoy! To buy tickets for Dame Sarah's performance at the Cheltenham festival on Saturday 5 July click here; https://www.cheltenhamfestivals.org/events/berlioz-te-deumYou can find us on the socials here;Instagram @threeinabarpodTiktok @threeinabarpodThree In A Bar on YoutubeAnything you'd like to share with us? Any guests you'd love to hear or anything you'd like us to do better? Drop us a line at hello@threeinabar.com Hosted on Acast. See acast.com/privacy for more information.

Labhair muid le Martha Campbell, ball den ceolfhoireann, agus iad le páirt a ghlacadh sa mhór-fhéile don chéad uair.

Cellist Sheku Kanneh-Mason was born in Nottingham in 1999 into a big musical family. He and his six siblings all grew up learning classical instruments, and appeared on Britain's Got Talent in 2015. Sheku first made his mark as a solo performer the following year when he won the BBC Young Musician Of The Year competition. In 2018 a global audience of over a billion watched him perform live at the wedding of the Duke and Duchess of Sussex. Since then he has received two classical Brit awards, An MBE for services to music, and performed at the Proms every year since 2017. His book The Power Of Music charts his creative journey, whilst his new album - his fifth release - includes recording of works by Shostakovich and Britten. Sheku talks to John Wilson about the early influence of his paternal grandfather, a classical music lover who encouraged an appreciation of chamber music, including Schubert's Trout Quintet. Sheku also discusses his cellist heroes Jacqueline du Pré and Mstislav Rostropovich and explains how the music of reggae superstar Bob Marley has been an inspiration throughout his life.Producer: Edwina Pitman

Prof. Comi stellt die Arbeit der Europäischen Charcot-Stiftung vor, die dazu beiträgt, das Leben von Menschen mit MS weltweit zu verbessern. Auf meinem Blog kannst Du den Beitrag nachlesen: https://ms-perspektive.de/303-ecf Diese Podcast-Folge ist dem Andenken an Prof. Giancarlo Comi gewidmet – einen herausragenden Neurologen, engagierten Forscher und langjährigen Präsidenten der European Charcot Foundation. Er hat mit seinem Wirken die Versorgung und das Verständnis für Menschen mit Multipler Sklerose entscheidend geprägt und hinterlässt ein beeindruckendes wissenschaftliches und menschliches Vermächtnis. Ich hatte die große Ehre, dieses Interview mit ihm auf Englisch zu führen – nur wenige Monate vor seinem Tod. Ohne die Unterstützung der Gemeinnützigen Hertie-Stiftung wäre dieses Gespräch nicht möglich gewesen. Dafür danke ich von Herzen. Das Gespräch ist ursprünglich auf Englisch erschienen und kann weiterhin in der Originalfassung gehört werden. In dieser überarbeiteten und übersetzten Version möchte ich Dir Prof. Comis Arbeit zugänglich machen und seine Gedanken und Visionen weitertragen. Inhaltsverzeichnis Einführung – Wer ist Prof. Giancarlo Comi? Die European Charcot Foundation Der Charcot Multiple Sclerosis Master Weitere Aktivitäten der European Charcot Foundation Schnellfragerunde Verabschiedung Einführung – Wer ist Prof. Giancarlo Comi? Prof. Giancarlo Comi: Ich bin Professor Giancarlo Comi, Neurologe. Zurzeit bin ich Ehrenprofessor an der Vita-Salute-Universität in Mailand, Präsident der European Charcot Foundation und Vorsitzender des Wissenschaftlichen Komitees der Human Brains Initiative der Prada Foundation. Außerdem leite ich das MS-Zentrum an der Casa di Cura Igea in Mailand. Nele von Horsten: Das klingt nach einem sehr engagierten und erfüllten Berufsalltag! Welche ermutigende Botschaft möchten Sie Menschen mit MS mitgeben? Prof. Giancarlo Comi: Für neu diagnostizierte Patient:innen: Seien Sie zuversichtlich. Dank moderner Therapien ist ein Leben ohne schwerwiegende Einschränkungen heute in vielen Fällen möglich. Für Menschen mit längerer Erkrankungsdauer oder bestehenden Einschränkungen: Es gibt vielversprechende Entwicklungen – auch im Bereich der modernen, interdisziplinären Rehabilitation. Und für alle gilt: Eine engagierte Zusammenarbeit zwischen Patient:innen, Ärzt:innen und Organisationen ist der Schlüssel zum Fortschritt. Nele von Horsten: Prof. Comi, vielen herzlichen Dank für das spannende Gespräch, Ihr Engagement und Ihre Zeit. Herzliche Grüße nach Mailand! Prof. Giancarlo Comi: Es war mir ein Vergnügen. Alles Gute – auf Wiedersehen! --- Bis bald und mach das Beste aus Deinem Leben, Nele Mehr Informationen und positive Gedanken erhältst Du in meinem kostenlosen Newsletter. Hier findest Du eine Übersicht zu allen bisherigen Podcastfolgen.

How did characters develop in the 2024 season? Promises of novelty, universe expansions and contractions, character conflict, audience relationships, storytelling worlds, & much more is discussed in this look at the second year of Russell T Davies' return. (00:00:00) Overall feelings on S1 (00:05:12) Expectations & reality of RTD's return (00:11:20) Promises of newness vs. the outcome (00:15:21) Considering 2024 S1 against other seasons (00:19:56) Tracking S1's narratives (00:21:01) Church: Ruby & 15's worlds (00:28:34) Church: character conflict (00:32:48) Space: story & arcs (00:40:03) Space: character conflict (00:42:30) Chord: Ruby & 15's development (00:46:45) Boom: Moffat's take on Ruby & 15 (00:52:42) Boom: character conflict (00:54:48) Yards: Ruby's acceptance (00:59:03) Bubble: Ruby's acceptance (01:03:43) Rogue: heart-to-heart moments (01:07:27) Legend: arc focus & Susan (01:12:57) Empire: story, arcs, character (01:26:06) Strengths of 15's character (01:32:46) Fourth wall + editing (01:39:23) Comic-Con: canon, friendship, Star Trek (01:42:51) Comic-Con: RTD reflections (01:56:08) Comic-Con: Whoniverse, announcements, IP, acting, leaks (02:20:06) Mel, family, VHS (02:23:32) Doctor Who at the Proms (2024) (02:57:44) Bubble's premise, 15's characterisation, Yards' ambiguity, S1's shape (03:13:37) The spinoff (03:30:19) Season 3 + reflecting on the revived series (03:35:20) Wobbly empire + audience relationship + streaming bubble (04:09:31) Individual seasons as individual ‘worlds' (04:22:12) Looking forward … Continue reading →

We're looking through Series 6 again because the script book could tell us some new things about it. We'll be trying to pick up on things we missed first time round, and sharing new revelations (and ridiculous theories) brought to light by the books. We might need your help.  If you haven't heard our reaction episode to Last Night of The Proms, we recommend starting there. Maybe not the immediate live reaction one...try this one: https://aquietnightinsideno9.libsyn.com/63-last-night-of-the-proms-inside-series-six-episode-six  Please get in touch with any of your reflections. Email us: aquietnightinsideno9@gmail.com, or find us on Bluesky: https://bsky.app/profile/aqnin9.bsky.social  Fancy supporting the show? Drop us a donation here: https://www.paypal.com/paypalme/aqnin9

Hi there! Happy Tax Day (sort of). Here's a look at our top local stories for Tuesday, April 15. Find the complete articles and much more in today's paper and online at https://www.iolaregister.com/.

In Episode 33 of The Classical Circuit, host Ella Lee talks to Jane Mitchell, Creative Director of the Aurora Orchestra (and also their Principal Flautist), about the ensemble's fresh approach to performance. Jane talks about the evolution of the Aurora ‘orchestral theatre' format, which involves the orchestra playing from memory, and their upcoming project 'Carnival', part of their 20th anniversary celebrations this year. She also reflects on their groundbreaking Beethoven 9 at the 2024 Proms, discusses the intention of 'revealing' all the music has to offer, and offers her insights into bringing musicians and management closer together. -------------------Aurora Orchestra:WebsiteFacebookInstagramTikTok-------------------Follow The Classical Circuit on InstagramDid you enjoy this episode? If so, ratings and follows help a lot with visibility, if you have a spare moment... *bats eyelashes*No offence taken if not.--------------------Music: François Couperin - Le Tic-Toc-Choc ou Les MaillotinsPerformed by Daniel Lebhardt--------------------The Classical Circuit is made by Ella Lee (producer by trade, pianist at heart). Hosted on Acast. See acast.com/privacy for more information.

The Cork Proms are taking place over five nights in the Cork Opera House this month. Mairead has been chatting to Trevor Ryan who is involved in the Musical Theatre Concert at the Proms. Hosted on Acast. See acast.com/privacy for more information.

In this episode, Dan & Julia talk to Katie Derham, BBC Radio 3 broadcaster, Queen of the Proms, and Strictly Come Dancing finalist, about how she combines her love of gardening and music. Julia grows tomatoes from shop-bought fruit, and Dan shares alternative Easter gift ideas. Your hosts round off with a list of jobs to do in your garden over the Easter holidays.Katie's Instagram account - https://www.instagram.com/thekatiederhamMusic in Bloom on BBC Radio 3 - https://www.bbc.co.uk/programmes/m001yr8jDan's alternative Easter gift ideas - https://www.dancoopergarden.com/collections/easterWebsite links:Dan Cooper GardenParker's PatchKew WakehurstExpertly produced by Scott Kennett at Red Lighthouse Local Hosted on Acast. See acast.com/privacy for more information.

Now that spring is here, we think back to what makes it so special in the South. It's prom season, spring break, and pollen is everywhere. We wax nostalgic on what this time of year was like for us growing up. Website: http://bamageeks.com Become a Bama Geeks supporter: http://www.bamageeks.com/join Available on Apple Podcasts (iTunes), Amazon, Spotify, and YouTube. Come sit a spell on the Bama Geeks Front Porch: https://www.facebook.com/groups/bamageeksfrontporch Check out and follow our socials! Facebook: https://www.facebook.com/bamageeks Instagram: https://www.instagram.com/bamageeks Twitter: https://twitter.com/bamageeks YouTube: http://www.youtube.com/@BamaGeeks TikTok: https://www.tiktok.com/@bamageeks

Pippa speaks to organiser Graham Todd about his event, Last Night of the Proms, the music involved and the event.See omnystudio.com/listener for privacy information.

MS can limit your ability to get around and do the things you like to do. And when that happens, the right mobility device can be a game-changer when it comes to staying safe, staying active, and improving your quality of life. This week, Dr. Evan Cohen joins me to discuss how to know when it's time to consider a mobility device, and how to choose the right mobility device for you. We're also presenting findings from two separate studies that shed significant light on how the gut microbiome interacts with the brain and how its composition varies among individuals with MS. We'll tell you what happened when a research team gave a multiple-choice "test" measuring MS expertise to neurologists and neurology residents and then gave the same test to the leading artificial intelligence platforms. And we'll share an opportunity for you to participate in MS research by taking the PROMS Initiative's eHealth survey. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Choosing the right mobility device  :22 Differences in the gut microbiome of people with MS  1:28 Evidence shows the vagus nerve is the connection between the gut and the brain  3:53 Who won the "MS expertise" showdown between neurologists and AI?  6:18 Your opportunity to participate in MS research by taking the PROMS initiative survey  8:31 Dr. Evan Cohen shares everything you need to know about choosing a mobility device  10:27 Share this episode  30:57 Have you downloaded the free RealTalk MS app?  31:15 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/391 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS STUDY: Alterations in Gut Microbiome-Host Relationships After Immune Perturbation in Patients with Multiple Sclerosis  https://neurology.org/doi/10.1212/NXI.0000000000200355 STUDY: Select Microbial Metabolites In the Small Intestinal Lumen Regulates Vagal Activity Via Receptor-Mediated Signaling https://cell.com/iscience/fulltext/S2589-0042(24)02926-2 STUDY: Artificial Intelligence Versus Neurologists: A Comparative Study on Multiple Sclerosis Expertise https://sciencedirect.com/science/article/abs/pii/S030384672500068X RESEARCH PARTICIPATION OPPORTUNITY: The Global PROMS Initiative eHealth Survey https://proms-initiative.org Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 391 Guest: Dr. Evan Cohen Privacy Policy

Wie gut weißt du wirklich, wie es deinen Patient:innen geht?Wie wir darin besser werden können, das erzählt Georg Supp in dieser ausgesprochen spannenden und lehrreichen Folge. PROMs haben (auch am Valentinstag) nichts mit Abschlussball zu tun, sondern es handelt sich um eben diese Weiterführung der Frage "Wie geht es Ihnen?".Wie wir besser verstehen können, wie es Patient:innen geht, wie wir dadurch erfolgreicher behandeln und zufriedener in unserer Arbeit werden können - Ist Georg seiner Zeit damit voraus?Wir glauben nicht! Hör dir jetzt diese spannende und besonders praxisnahe Folge an!Hier findest du alle spannenden Links zum Thema:mophys:https://mophys.de/de/ Webinar am 19.2.2025 um 19.00: https://mophys.de/de/webinarIn dem Live-Webinar erhältst Du einen praxisnahen Einblick in mophys. Profitiere von den wertvollen Erfahrungen unserer Expert*innen und entdecke, wie mophys den Alltag in der Physiotherapie verändern kann. Stelle Deine Fragen direkt und erfahre, wie mophys in Deiner eigenen Praxis zum Einsatz kommen kann. Zum Thema PROMIS:https://www.healthmeasures.net/explore-measurement-systems/promis Bertelsmann-Stiftung zum Thema PROMs:https://www.bertelsmann-stiftung.de/de/unsere-projekte/gesundheitsversorgung-qualitaetsorientiert-steuernInterview mit Prof. Matthias Rose von der Charité:https://open.spotify.com/episode/2oWML8UC7b3RyODHfaED68?si=57bc84b647ea4e00&nd=1&dlsi=a8d5cd0889124e08Jede einzelne Folge von "Autsch - der Schmerztalk" als Podcast findet ihr auf den gängigen Plattformen wie Spotify, Apple Podcasts etc.Reserviere dir direkt einen Platz in einem unserer Kurse:www.best-therapie.com/kurseOder lass dich unverbindlich auf die Warteliste setzen, um nichts mehr zu verpassen:www.bestliste.de#BEST #basiseffektiverschmerztherapie #schmerz #autsch #schmerzen #schmerztherapie #physiotherapie #ergotherapie

American conductor Marin Alsop was the first woman to lead major orchestras in the UK, South America and in the United States, becoming principal conductor of the Baltimore Symphony Orchestra in 2007. Nominated for Grammy Awards five times, in 2013 she became the first ever woman to lead the Last Night Of The Proms, and is now regarded as one of the greatest conductors in the world. She talks to John Wilson about her professional musician parents who nurtured her love of music and supported her career choice from the age of 9 when she first revealed she wanted to be a conductor. Marin also talks about Leonard Bernstein, the great American composer and conductor, who inspired her ambitions and later became a mentor to her. She also chooses Carl Jung's work The Archetypes and the Collective Unconscious, and explains how his theories have helped her in leading orchestras around the world.Producer: Edwina PitmanMusic and archive used: Serenade in C major for String Orchestra, Op. 48; Valse, Pyotr Ilyich Tchaikovsky, New York City Ballet Orchestra, 1986 Irish Spring commercial: "Clean as a Whistle" 1980 Leonard Bernstein, Young People's Concerts: "What is Classical Music?", CBS Television, 24 January 1959 Omnibus: Leonard Bernstein's West Side Story, BBC2, 10 May 1985 Archive of Leonard Bernstein and Marin Alsop at the Schleswig-Holstein Musik Festival, 1987 Leonard Bernstein, Young People's Concerts: "What Does Music Mean?", CBS Television, 18 January 1958 Archive of OrchKids concert, Baltimore Symphony Orchestra Woman's Hour, BBC Radio 4, 26 July, 2005 Rhapsody in Blue, George Gershwin, Jean-Yves Thibaudet, Baltimore Symphony Orchestra, Marin Alsop Last Night of the Proms, BBC1, 7 September 2013 Symphony No. 2 in C Minor, "Resurrection", Gustav Mahler, Polish National Radio Symphony Orchestra, Marin Alsop

Philip and Dwayne give their reviews of the Doctor Who related releases from Big Finish released in December 2024. They also share their thoughts on the recently released Doctor Who at the Proms, The War Games in Colour and Joy to the World. Theme music by Joe Kraemer. Website - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.sirensofaudio.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow us on Instagram - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://instagram.com/audiosirens⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow us on Facebook - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/audiosirens⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow us on X - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://x.com/audiosirens⁠⁠⁠⁠⁠ Follow us on Bluesky - ⁠⁠⁠⁠⁠https://bsky.app/profile/audiosirens.bsky.social

In this episode, we explore the importance of patient involvement in shaping rare condition research initiatives. Our guests discuss why it's crucial to involve individuals with lived experiences, including patients and caregivers, in setting research agendas. In doing so, this approach ensures research can be more inclusive, efficient, and impactful, addressing the issues that matter most to those affected. Mel Dixon, Founder Cure DHDDS and member of Genomics England Participant Panel is joined by Jo Balfour, Founder of CamRARE and Dr Rona Smith, Senior Research Associate at the University of Cambridge and Honorary Consultant in Nephrology and Vasculitis. Find out more about the Cambridge Rare Disease Research Network, discussed in the episode, which aims to support the rare condition community in building an online network of partnerships and resources to facilitate new patient-centred research opportunities. "We're really turning research on its head, moving away from it being a researcher-led activity where they decide on the idea and the research concept and bring patients in at different points along that research journey and instead starting with the patient's idea in the first place.  It can only be a better system for all because it improves efficiency, it improves potentially the long term outputs and, most importantly, outcomes for patients." You can download the transcript or read it below. Mel: Welcome to Behind the Genes. Rona: I think it really means that we measure what matters to patients and individuals that are affected.  Often, it's really difficult to capture kind of the real impact of disease and there's a tendency for researchers to measure things that are easy to measure and are reproducible, which of course is important but what's most important is actually being able to truly capture the impact of an intervention on an individual's condition.  So, I think that's another key aspect of having people with lived experience involved right from the start. Mel: My name is Mel Dixon and I'm a member of the Participant Panel at Genomics England and founder of Cure DHDDS, a charity set up to raise awareness, support families and help drive research into the ultra-rare DHDDS gene variant.  On today's episode I'm joined by Jo Balfour, Managing Director of CamRARE, which is the Cambridge Rare Disease Network.  This network unites patients, advocates, experts and leaders to address the challenges faced by people affected by rare conditions.  I'm also joined by Rona Smith, Associate Professor at the University of Cambridge and honorary consultant in nephrology and vasculitis.  Today we'll be discussing the role of patients in setting research agendas and how their involvement can lead to more impactful and patient-centred research.  If you enjoy today's episode we'd love your support.  Please like, share and rate us on wherever you listen to your podcasts. Before we begin the interview I'd like to share a little bit of my story.  In November 2022, following whole genome sequencing, we received the news that two of our three children carried a neurodevelopmental and neurodegenerative DHDDS genetic variant.  At the time of our children's diagnosis there was very little information on our gene, minimal research happening into it and no treatment pathway.  Through our charity, Cure DHDDS, we have worked tirelessly to instigate research and create a collaborative scientific research community.  I am a huge advocate for patient-led research and have witnessed first-hand the positive impact it can have on patient lives.  Thanks to the work of the many scientists that we have had the honour of collaborating with, within two years of our children's diagnosis we have a disease-modifying therapy in our sight and an ASO (Antisense oligonucleotides) therapy in development.  We are incredibly grateful for the opportunities genetic testing has given us but I also appreciate how overwhelming a genetic diagnosis can be and how challenging it can be for families to initiate research projects with little to no resources, and that's why initiatives such as CamRARE that we'll be discussing today are so important.   On that note, let's get back to our podcast guests.  I wonder before we dive into today's topic if you could both give a brief introduction, and, Rona, if you could also give the less scientifically-minded of us an explanation about what nephrology is. Rona: Thank you for inviting me today.  So I'm Rona Smith, I work in Cambridge and I'm a nephrologist and that means somebody that looks after individuals who have diseases that affect their kidneys.  My specialist interest is in something called vasculitis which is a rare autoimmune disease that affects all organs in the body but kidneys as well.  Mel: Thank you.  And Jo?  Jo: Hi Mel.  I'm Jo Balfour, the Managing Director and one of the founding members of Cambridge Rare Disease Network, or CamRARE for short.  I think we're often described as the ‘Chief Everything Officers'.  I manage the charity and all of our operations and our wonderful team.    Mel: Lovely.  Thank you very much.  Rona, I wonder also if you could explain to our listeners what is a research agenda?  Rona: So in brief a research agenda is really a strategy that outlines key questions or topics that a research community, and that might be investigators, clinicians, scientists, patients, industry,  and they are the priorities that they want to explore and address over a period of time.  So it's really a direction of travel and identification of areas of importance and where there are gaps in knowledge so that it then leads to the opportunity to form specific research questions that you can then go on and address.  Mel: Why do you both think it's important to involve patients in setting these research agendas?  Jo: Well I think critically one of the things that I've learnt over my time working, not just in the rare disease sector but also earlier in social care and education, is that we should as professionals never assume anything; you know, we have not lived in their shoes and we don't know what the daily life of people living with rare conditions is like.  So gathering that day to day lived experience is really crucial.  And I have a unique opportunity to see into that daily life with our local community of rare disease families who have a range of different rare conditions.  I'm party to their conversations, to their daily trials and tribulations, the things that are difficult, the things that they find joy in but I still will always go back to them and ask their opinion.  I see myself as a spokesperson for them as we're an umbrella organisation but I certainly never really know what it's like to live with their conditions.  I think they bring with them diverse experiences which we really need and value in setting research priorities, they have unique knowledge of their own conditions.  They ethically have a right to be involved from the start and to set that priority and agenda but, equally, it's valuable for us as researchers because if we can involve people early we have definitely more chance of good engagement and later success, better outcomes for everyone.  Mel: Couldn't agree more.  And, Rona, is there anything you'd like to add to that? Rona: I think it really means that we measure what matters to patients and individuals that are affected.  Often it's really difficult to capture kind of the real impact of disease and there's a tendency for researchers to measure things that are easy to measure and are reproducible, which of course is important but what's most important is actually being able to truly capture the impact of an intervention on an individual's condition.  So I think that's another key aspect of having people with lived experience involved right from the start.  Jo: Another thing that's actually quite interesting that I'm going to mention here is that I think when you live day in, day out with a condition your perception of things like pain is different from your average person's so you become almost accepting of your daily norm, and I think that's really critical to understand as well.  And it's only by getting to really know patients and understand. When we say, “What's your pain like on a scale of 1 to 10?” you know, something that I feel as pain because I get it rarely I probably am going to put it at a higher score than somebody who has that every day.  So I think there's subtleties and nuances like that as well which are really critical to get across by conversation with patients.  Mel: That makes absolute sense.  And I see that from the patient perspective myself.  I was out with my friends the other day and they said, “Oh my goodness, you're constantly taking your children to sports activities.”  Because of their physical needs we're constantly,  they go to Pilates, they go to swimming, they go to gym class – we try to keep them fit and healthy – and we, even though they're older, have to take them there and back and that's become our norm but when you're speaking to families whose children don't have those difficulties they have no idea how much time that actually takes up.  And I had no idea how much like time it takes up compared to what other people are doing because that is our norm, that's what we've accepted as the norm.  Patients and patient groups are incredibly driven and invested in their rare disease as well so they make really good rare disease research partners.     And, moving on, what do you see as the challenges and barriers to patient involvement and how do we overcome these? Rona: I think probably the biggest barrier is time.  So, the most important thing is investing time to build relationships, to really understand in-depth perspectives both from the patient's side but also the researcher's side. And, inevitably, we always want to do things faster and actually this is one really, really critical aspect is investing time.  Funding is also a challenge.  Often you have to do a lot of upstream work before you have got funding for a project and that takes time from individuals and that's another challenge.  And I think the third thing for me is individuals that are patient partners in research, they're not just patients, they're people - they have lives, they have work, they have families, they have everything else that goes on in life - and so actually fitting this all in is really challenging.  Mel: Jo, is there anything you'd like to add there?  Jo: Yeah, I think just a word about diversity really and, you know, how do we uncover those hidden families and patients who currently don't really have a voice.  I think we'd all acknowledge that there are key voices within the rare disease community who will share the views of their community and they've become well-oiled machines almost at being great advocates but, as I mentioned earlier, even though I'm perhaps one of those people, you know, I speak for a community, I would never assume anything.  So, I still need to uncover the thoughts and the feelings and the emotions and the needs and the what matters from those people, and, as Rona mentioned, that takes time and it takes building relationships and trust with people.  So, we have a wonderful community in the Eastern region of England which is made up of families affected by all different rare diseases, and undiagnosed.  And some are babies and have been lucky enough to get a very early diagnosis and others are young adults but what we're finding through that is that experience is diverse and experience changes over time as families go through transition periods or they meet a roadblock and they're having to navigate things differently.  So, it's about building those relationships.  That takes times, it takes resources, it takes sometimes a reset in the way that we think things need to be done.  So instead of asking questions all the time and putting surveys out and trying to get response that way it takes a bit of thinking about how do we listen better and how do we give those people who don't have a voice, who are non-verbal or perhaps have a learning disability, how do we ensure that we're capturing their views as well.    And we did a really lovely project actually last year, it was something funded by the NHS called My Story, My Way, where we actually spent three months with our young adults working out what it was they wanted from our community next, how did they want us to follow them into adulthood.  And we knew that there were a number of young people in that group who were non-verbal and had some learning differences and we knew that we couldn't just do it in the normal format, we couldn't just do a focus group and ask their opinion, so we actually did it through photography.  So each of the familiess well, the young person themself was given a simple camera.  They basically had thirty-six shots.  You got thirty-six clicks to capture the things, the people, the places that you love and then to share them with us as a community.  And then we all discuss, you know, how these things might be something we can build into our future plans for them.  And it was such a wonderful activity.  We gave them plenty of time, plenty of opportunities to ask questions.  If the young person themself couldn't physically click the camera their sibling got to help them.  And their sibling or their parent was given another camera in black and white so we had distinctive pictures, pictures that the kid themself had taken, pictures that the family had taken, but all together, you know, it gave this lovely kind of medley, this beautiful visual representations of what mattered to them.  And I think it's about taking the time to be creative with people like that and really get to the bottom of “How do we find out what matters to you?” Mel: Although it takes time to think about those ideas.  That could be translatable across the board really, couldn't it, throughout various conditions.  I think that's fantastic.  Rona, I wonder if you can tell us how has the work that's already been done through the patient-led research hub facilitated addressing research priorities.  Rona: So just a tiny bit about the patient-led research hub.  So, this has been now running for nearly ten years through Cambridge.  It's a partnership between the Cambridge Biomedical Research Campus and we're based within the university and the Trust.  And in essence it kind of was set up because of really a mismatch between what many patients wanted from research and what investigators' views were.  And so really the premise is that we welcome patients to come to us with an idea, a problem, an unmet need in their disease area – and we do focus on rare disease – and we work with them to see “Well actually what do we already know about that?” and then if there is a gap in knowledge we then move to kind of trying to work and develop a question that we can then address.  And that might be a question that's addressed through generating more information through surveys or it may actually be a question of an intervention that we can test.  So, we've had lots of projects come through and we, just an example of a project was from a group of patients with a rare kidney condition called autosomal dominant polycystic kidney disease, and that is a condition where over time you accumulate cysts in your kidneys and the kidneys become large, they become very painful and eventually they can fail.  And a question that the patient group had was about whether drinking more water could impact the rate of growth of these cysts, and there's a strong hypothesis behind that that drinking lots of water reduces down the level of a particular hormone.  And we actually worked with the charity behind this group, the Polycystic Kidney Disease Charity, and designed a study to test a very high water intake to a normal water intake to see whether it was possible over a period of eight weeks for patients to actually stick to this.  It's quite difficult to do.  And they recorded how much water they'd drunk, they tested their own urine and actually it showed that this was feasible to do this kind of work.  So, I think the patient-led research hub is kind of taking the research priorities that are important to patients but working in a patient-led way to come right through to a project.  Mel: That sounds great.  And if the patients are engaged from the start of the project and it's led by them they're obviously going to be much more driven to take part in the actual research and see the research through themselves.    So, Jo, I'm very excited to hear about the launch of the Rare Disease Research Network.  Can you please tell me what the research network is and what you hope to achieve with it?  Jo: So the Rare Disease Research Network is first of all a bit of a mouthful so we're going to try and encourage people to call it the RDRN.  It's a co-created project which really the patient-led research hub in Cambridge approached us about in 2022, I think, we started talking about this, approached CamRARE as a partner to apply for an NIHR partnership grant, and we were successful with that to really take the model that the patient-led research hub had already developed and found was successful, and perhaps too successful for its own good – they were receiving more applications and more ideas than they could manage – and to develop that into an online platform.  So taking the same model, making it more accessible to a wider group of people, potentially worldwide, and providing the hand-holding that the patient-led research hub has always done, helping patients really consider their question, formulate that into a research idea, then do the literature search to find out “Is this question already answered, and if it is, great, can we provide that information to our community?  If it's not, how do we then build a team?  Who needs to be in my research team?  How do we then get funding together to take this idea forward?”  So, it's really taking the model, taking the good practice that already existed and creating an online platform to really attempt to replicate that as best we can. So the platform will launch on 23rd November (2024) at CamRARE's Rarefest which is a lovely in-person activity that's going on in Cambridge, and that platform will be open to anyone who has an interest in rare disease research.  But I think, critically, what's different about this is that, you know, we've talked about setting research agendas and we've talked about patients contributing to that, contributing to setting the priorities, what's different here is that the patients decide on the questions; it's what matters to the patients coming from them and their community.  And it's an opportunity for them to showcase those questions and those idea on a platform and almost to have a call to action, “Is there anyone else on this platform who has similar research interests to me?”  The platform will matchmake them together through a series of choosing tags, choosing tags about particular disease areas -  It's linked to the Orphanet database - choosing tags about the type of research that you're interested in.  That matchmaking process will happen, which at the moment is a very serendipitous process but we hope to take it a little bit further on from that.  It's still going to be a little bit of potluck who's on the platform at the time who's got similar interests as you but hopefully it will improve that serendipitous system.  And it will allow them to access resources on the platform, which is the kind of hand-holding bit, and also, critically, some mentoring.  So, there's a real sort of opportunity here for professionals – researchers, industry partners, healthcare professionals – who have particular skills in research to be able to say, “Well I can help.  I might not be able to be part of your team at this point but if you need half an hour on a Zoom call with me to think about your research question I can offer to mentor you on that.”  But, likewise, I think there's going to be lovely opportunities here for patient groups to support each other too because what we've always realised is that patient groups are at different points of their research journey.  You know, we see some organisations that are really well-funded now who are in partnership with industry, you know, they have a group of pharma companies that are supporting the development of treatments and they've kind of reached that point where they're very highly skilled and very well experienced.  And then there's others who are mum and dad who've just had a recent diagnosis for their child, they've gone searching on the internet, they can't find information, they don't have a patient organisation to rely on so they're going to make one themselves.  This happens all the time in the rare disease field.  There are 11,000 different rare conditions and there's not a group for all of them so mum and dad will often start something themselves and then in lots of cases want to do some research, they want to answer some of these questions.  So, you know, they're really starting from a very different beginning stage here where they've going to need some help, and sometimes the best help comes from their peers, it comes from other patient groups.  So that's in a nutshell what it's about; it's about providing opportunity for patient groups to showcase their great ideas, build partnerships and take research forward.   Rona: The only thing just to add there is I think, although rare diseases are individually rare, collectively, as Jo said, they're quite common, there's 11,000 rare diseases, and often, although they all have distinct features, there are common threads through rare diseases in terms of maybe symptoms that patients experience or challenges that their rare disease brings.  So, for example, you may have symptoms of pain or seizures that are common across many conditions, there may be educational needs that are threads going through.   And groups could work together maybe to answer a question that's relevant to a number of conditions and so bringing people together for that.  Or there may be another group that's already tried to answer that question in their condition and you can learn what worked, what didn't work.  I think that's the other thing, is there will be common threads that come through, and I think that would be a real strength of the network to draw those people together. Jo: I think as well, Mel, if we take this back to what we said right at the outset about optimising success for patients by bringing them into the conversation early, I think this platform provides the perfect opportunity to do that.  So we're moving away from, we're really turning research on its head, moving away from it being a researcher-led activity where they decide on the idea and the research concept and bring patients in at different points along that research journey and instead starting with the patient's idea in the first place.  It can only be a better system for all because it improves efficiency, it improves potentially the long-term outputs and, most importantly, outcomes for patients.  Mel: We were that family, that mum and dad setting up the charity a year and a half ago for the ultra-rare disease that our children had.  I think, you know, the match-making opportunities that are here are fantastic because finding yourself in that position is incredibly isolating.  And not only the matchmaking opportunities with the researchers but, as you were saying, Rona, as well with similar diseases; there's so much to learn from other diseases that may have, I don't know, a similar phenotype in the cells or similar symptoms.  That's what we found from connecting with these other rare conditions.  So, for us it's lysosomal storage diseases, we've now got the opportunity potentially to piggyback on drugs better used for their diseases for our own ultra rare condition, you know, where for us to run a full-on clinical trial by ourselves with a new drug, I mean, we just wouldn't have,  there's no funding, there's not enough interest.  So, I think the opportunities that lie in this network are really, really exciting.  Jo, can you tell me a bit more about who can join the research network?  Jo: So anyone with a rare disease research interest. That's everybody from individuals affected themselves, their family members, their caregivers, the patient organisations, that support them, and then, you know, all sorts of rare disease professional researchers.  So, we're looking for PhD students who are looking for their first exciting project to undertake, have they taken a look at the Rare Disease Research Network to see if there's any ideas that might pique their interest.  We're looking for established researchers, medical professionals who are undertaking clinical research but also I think, importantly, companies.   You know, we hear more and more about concepts like drug repurposing for rare diseases where we're looking at the opportunities for taking drugs that already exist and have been proven safe to be redeployed to other rare diseases. It's quicker, it's more efficient, it's cheaper, so does it open up opportunities for companies that are using that technique to get involved.  And also pharma companies.  This platform is not all going to be about finding cures and treatments but it certainly will be a priority for some groups.  So we really are welcoming everyone with an interest in rare disease research to get involved, be part of the network, collaborate, help where you can. Rona: And also, as we've said before, once you've got that level of engagement and the patients leading these initiatives we've found, certainly with our group, the patients are much more willing to, say, find the MRI scans for the scientists, to have a blood sample done, to have skin fibroblasts taken.  If they know and they understand and they're driven and, as you said, the research idea has come from them as a patient group it certainly increases the chance of them being fully involved in the project from the start to the finish.  And all these things are imperative to understanding rare conditions because without researchers having the opportunity to look at these various samples you're not going to stand much of a chance of finding a treatment.  Jo: And we want the opportunity to upskill patients as well.  I think there are many people out there with great ideas who haven't yet found the confidence to promote those ideas because they're not quite sure of what the research journey looks like or what it might entail or whether they've got the right skills.  But I think by joining the platform and almost kind of watching how other people are managing these things and utilising the resources and the mentoring I do really hope that will build that confidence and those skills sets in people so that they can engage.  Rona: Yeah, just to add to that, I don't think it's just upskilling patients and patient groups, I think it's upskilling everybody involved in rare disease research.  This is quite a different way of approaching research, it's something that maybe academics may feel a little bit uncomfortable with, it's not how it's normally done, so I think there's a whole learning process.  And the aim is that this RDR network will evolve and will develop and the direction it goes will be driven by the community that are engaging with it.  So I think it's a really exciting time just as we're coming up to launch to see where this goes.  Jo: Mel, you've been involved in this project, it would be really interesting actually to hear from you. I was just thinking, as part of the co-creation community we had 25 individuals from the rare disease community who built this platform from scratch with us; Rona and I might have set out all the vision for how we wanted the platform to be or what we thought might be a good idea but ultimately it was the community who decided and they literally have fact-checked and cross-referenced every word that's gone on the platform. What has that experience been like for you as a patient representative?  Mel: I think it's been really welcome to see a network that is truly putting patients at the centre of everything.  So, from the very beginning foundations you have the rare disease community involved which is exactly what you're trying to create through your network.  So, I think it's been very welcome to be involved in the project and I also think that hopefully it will sort of be self-perpetuating that this will start to press a reset button on how we think about rare conditions and how it needs to be a more equitable field with patients.  Because I think, as you've both alluded to, while some clinicians and researchers are very onboard with this, for others it's a new concept that they still need to potentially adjust to or get their head round because it is a different way of thinking.  But in rare disease, well, in any condition really but particularly rare disease because there's so few experiences to draw on, I think that patients are vital to moving forward and to making that change so that diseases and conditions that have previously had no treatment, like, hopefully this way of thinking can expedite those treatments because, well, as a rare disease representative myself for our community that's one of our biggest drivers.  We're dealing with a condition that's progressive that affects most of our community's children; that is what we want, we want treatment, we want something that can stabilise the conditions.  You know, you can have researchers doing random projects that would make no difference to the final outcome of patients but if researchers know it's a priority of this particular group, hopefully that can channel in their focus and get the outcomes that the patients want in a more timely collaborative way.  So, I am a huge advocate for what you're doing, I think it's an incredible initiative.  Is there anything either of you would like to add to that? Rona: Rare disease disproportionately affects children and young people.  So, 7 out of 10 rare diseases develop in childhood and at the moment the Rare Disease Research Network hasn't really got a forum for including children and young people, and really that's partly because, and Jo can speak much more eloquently to this with her experience.  Actually, we didn't do that at the start because we feel that this is actually a discreet piece of work that really needs to be done in collaboration with children and young people to make sure that it's done well so that they can engage in the platform. So, Jo, I don't know if you want to talk about how we're hoping to take this forward.  Jo: Yeah, so we're busy developing a project plan at the moment which we're hoping to get funding for to work over eighteen months with a team of young adults with rare conditions, probably from our Unique Feet community and keep it local because we already have a good relationship with them and they have our trust.  But the idea would be to work with lots of other young people's forums.  So there's already ones established in and around our area, such as Pedal, which works with really small children, and there's also groups that are set up for young people with cancer.  So we've already had lots of great conversations with them about how we can work with them, how they can help us sense-check our project, and then in return we can help them better understand research and their ability to be involved in that.  But ultimately by the end we want to run focus groups, we want to develop some peer mentors within our community, so young adults who've, you know, perhaps come out the other end of a period of transition into adulthood who can support other young people with rare diseases to also become researchers, to come up with their own ideas and their own questions, and to sense-check projects that come through the platform.  So it's a really exciting opportunity to truly involve the people who are affected most by rare conditions but we know through our My Story, My Way project that this has to be done gently, carefully, given time and done really thoughtfully.  So that's our next step and we hope to be able to share those learnings with people so that it can be done elsewhere.  Mel: And do you see the network also working with children with learning differences? Jo: Absolutely.  We'll invest a lot of time and energy in ensuring that materials are accessible, inclusive and suitable for the community that we're working with.  Mel: So looking to the future, how do you think, Rona, can patient-led research help to shape the future landscape?  Rona: So I think, Jo used the term earlier, kind of this is really turning research on its head, so it's really putting patients right at the centre of research, so it just makes sure that it's absolutely driven by what matters to them to get the outcomes that matter.  And, again, it's just got all that benefit of efficiency and really answering those questions that matter.  Mel: And, Jo, do you think this could lead to more collaborative partnership, for example, between industry and academia, potentially leading to quicker clinical advancement? Jo: I would absolutely like to think so.  You know, as CamRARE we run a companies forum which is a roundtable meeting for pharma and biotech companies and other organisations like Genomics England who are involved in the rare disease therapeutic space and diagnostics, and I think one thing that I find really heart-warming about those meetings is that, you know, different companies are able to sit around a table as competitors but with a very open mind to addressing the barriers and the bottlenecks that prevent them from getting drugs to patients.  Because of course it's not just the research journey that's a challenge, it's the regulatory side of things at the end of that journey; just because you've created a great drug it doesn't matter in the end if it doesn't get to the patient.  So, you know, access is critical and involving patients at the earliest possible moment to ensure that that treatment gets through to the regulators and gets access to patients is the only way forward.  We had a recent companies forum meeting where we were exploring health-related patient reported outcome measures, or PROMs, and we had a speaker from NICE who's the regulatory body, we had a speaker from Sheffield University who was talking as an academic about developing PROMs for industry and for patient groups and we had Emily Reuben, the CEO of Duchenne UK, and we had an amazing discussion about the importance of involving the patient community from the outset.  And the academic explained that developing a PROM for Duchenne UK had taken them two years and it had taken them that length of time because they'd followed this careful thoughtful pathway of making sure that they didn't assume anything about what matters to patients.  But that of course, as we said earlier, involves time, it involves financial commitment, it involves resources and the right attitude, but I do think that a platform like the Rare Disease Research Network can really try to harness all of those things by bringing the right people together – industry, academia and patients – to work together equitably. Mel: And with the network do you think you'll be getting the regulators in at that initial stage as well so that, like you said, the patients can gain access while we're dealing with their priorities, the regulators are informed at the very earliest stages so that we know the process that's being followed will ultimately lead to patients gaining access to the relevant therapies?  Jo: Yes, I think this is really important, and there's actually, we've got a section on the new platform which really talks to each of the different stakeholders.  ‘What's in this for me?'  ‘Why is it important for you to be here and to join?'  And one part of that is funders and that includes the regulatory bodies.  And at the next companies forum meeting we're actually going to be bringing the Rare Disease Research Network Platform and its potential to the companies forum meeting and we'll have regulators involved in that.  So, you know, we are constantly talking to people about why it's important for them all to be involved and all to see what matters. I think I'd like to advocate for an extra letter at the end of PPIEP - if we could squeeze a D in there at the end too.  So over time that terminology has expanded to be Public Patient Involvement Engagement and Participation, which was added I think this year, but it would be lovely to have the D on the end and to include ‘Driven' because I think what's really important about this platform is that it's not just engagement and involvement, it's not just participation, it's initiated by and driven by patients. Mel: So I think we'll wrap here.  Thank you to our guests, Jo Balfour and Dr Rona Smith, for joining me today as we discuss the role of patients in setting research agendas.  If you'd like to hear more like this, please subscribe to Behind the Genes on your favourite podcast app.  Thank you for listening.  I've been your host, Mel Dixon, and this podcast was edited by Bill Griffin at Ventoux Digital and produced by Naimah Callachand. 

The Banff Patellofemoral Instability Instrument 2.0 (BPII 2.0) is a disease-specific, quality of life patient-reported outcome measure (PROM) that is valid and reliable in patients with recurrent lateral patellofemoral instability (LPI). Quality of life encompasses the physical, emotional, and psychological aspects of patient functioning and recovery.   In conclusion, a statistically significant correlation was evident between the BPII 2.0 and the other PROMs. The BPII 2.0 does not explicitly measure kinesiophobia or pain catastrophizing; however, the significant statistical relationship of the TSK-11 and PCS to the BPII 2.0 suggests that this information is being captured and reflected.   Click here to read the article.

Steven is a special correspondent from Chicago TARDIS this week while Chris and Warren hold down their respective home forts in Edmonton and Vancouver to bring you news of Disney+ promoting Joy to the World(s), an onslaught of BBC Doctor Who programming around Xmas including the aforementioned special, The War Games In Colour, and the Doctor Who Proms! We've also got Big Finish news, an auction by Who director Rachel Talalay of one of her amazing gum bichromate prints of a TARDIS set photo, and from Lombard (Chicago's Abbotsford) Steven's interview with Sacha Dhawan and Jo Martin! Links: Support Radio Free Skaro on Patreon Disney+ Doctor Who promo Disney+ Doctor Who promo not a typo? BBC Christmas 2024 TV and iPlayer line-up, includes Joy to the World synopsis UK TV License fee to increase with inflation Special ‘Joy to the World' Sonic Screwdriver available now Doctor Who at the Proms to run 109 minutes Space Babies script features a musical scene was cut Doctor Who Magazine 611 cover has callbacks to The Eleventh Hour Next Big Finish War Master box sets “His Greatest Trick” (due Oct/25), “Deeds Without Names” (due Oct/26) Big Finish Sirens in Time, the first release, gets special edition Doctor Who auction to support Children in Need happening Feb 2025 Rachel Talalay-signed Doctor Who 60th Anniversary Gum Bichromate Print at auction, supporting ACLU of SoCal Toby Hadoke's Absent Friends goes out Dec 29 @ 4:45pm Dec 29 Interview: Chicago TARDIS Sacha Dhawan Jo Martin

Toby Spence is an award-winning tenor, who has played the lead roles across the world in every major opera theatre from The Royal Opera House in Covent Garden to The Met in New York to La Scala in Milan. A frequent performer at The Proms and on acclaimed recordings, he has also brought classical music to popular audiences through shows like The Rob and Romesh Show. In this episode, Toby shares his journey to becoming one of the most sought-after tenors of his generation, his battle with thyroid cancer and the remarkable process of relearning to sing after surgery. Humble, witty and candid, this is a rich, touching and inspiring conversation. Related Links Toby the Tenor Toby's performance of Britten's ‘Serenade for Tenor, Horn and Strings' Prince Albert Gruss an der Bruder Toby Spence as Captain Vere in Billy Budd

This week we look at the United Kingdom - the farmers revolt;  Steve Reed and Tim Farron;  billions wasted on facemasks; Rachel Reeves; the UK at COP 29; Censorship and the NewsAgents; Alison Pearson; Mary Harrington; Euthanasia; Dancing Donald; Biden and World War; and Tony Campolowith music from the Waterboys, the Sex Pistols, the Wurzels, Last Night of the Proms; ELO; the Beatles; Racist Geology; Jaguar; the Village People; and Stuart Townend. 

Donald Macleod and Leah Broad survey the life and work of British composer Dorothy HowellThis week Donald Macleod is joined by the award-winning author Leah Broad to explore the story of the British composer Dorothy Howell, who shot to fame aged 21 after the triumphant premiere of her orchestral work ‘Lamia' at the Proms. By the mid-1920s she was regarded as one of the leading women composers of the day, performing in prestigious venues across the UK and regularly appearing on radio programmes in the earliest days of broadcasting. But she faced challenges from the 1930s onwards that left her disillusioned, and by the end of her life she wanted to destroy all but a handful of her works. Luckily family intervened, but even so Howell's music almost disappeared from view - until recently.Music Featured: Spindrift Humoresque for Orchestra Sonata for violin and piano (1st mvt) Two Frogs Five Studies for piano Boat Song for piano Lamia Five Studies Rosalind The Little Round House, The Bears Koong Shee Phantasy for violin and piano The Tortoiseshell Cat Pot Pourri My White Lady The Moorings If you will come to Corte Piano Concerto in D minor Mazurka Two Pieces for Muted Strings Puppydog's Tales Prelude 1 in F minor Prelude 2 in C Prelude 3 in A flat Recuerdos Preciosos No 1 and 2 The Rock Overture Sonata for violin and piano (2nd & 3rd mvts) To Sine in Winter Sonata for piano Three Divertissements Presented by Donald Macleod Produced by Megan Jones for BBC Audio Wales & WestFor full track listings, including artist and recording details, and to listen to the pieces featured in full (for 30 days after broadcast) head to the series page for Dorothy Howell (1898-1982) https://www.bbc.co.uk/programmes/m0023f35 And you can delve into the A-Z of all the composers we've featured on Composer of the Week here: http://www.bbc.co.uk/programmes/articles/3cjHdZlXwL7W41XGB77X3S0/composers-a-to-z

Music is undeniably a huge part of what makes video games special, both individually and on an industry-wide level. Not only is no gaming award show complete without a gong for the year's best soundtrack, but even the Proms have started acknowledging that video game scores have come a long way since the 8-bit days (without throwing any shade on chiptune, a legitimate genre in and of itself with some stone-cold classics). That's probably why, from huge AAAs to smaller indies, music can account for a significant chunk of any game's budget — and it's definitely worth the investment. For this episode, the Indieventure trio have pooled our vinyl collection to talk about some of our personal favourite indie game music highlights. I know you guys say you love long show notes but there's seriously no way I'm going to be able to list every track we talk about here — which is why we've put together [a YouTube playlist] that should cover everything instead! A quick overview, though, sees us talking about the music from games including Balatro, Bombrush Cyberfunk, Braid, Celeste, Crypt of the Necrodancer, Dear Esther, Death's Door, Dicey Dungeons, Disco Elysium, Everybody's Gone to the Rapture, Fields of Mistria, Firewatch, Hades, Hades II, Hellblade: Senua's Sacrifice, Hollow Knight, Hotline Miami, Hypnospace Outlaw, Journey, Kentucky Route Zero, Monster Prom 2: Monster Camp, Minecraft, No Straight Roads, Paradise Killer, Pizza Tower, Pyre, Return of the Obra Dinn, Stardew Valley, A Tower Full of Cats, Trombone Champ, Undertale, Unravel, and We Happy Few. If you'd like to hear every track we discuss in this episode in its entirety, we've added them all to a convenient YouTube playlist that you can find here. During the course of this chat we also promise you a couple of specific links, so go here for Bombrush Cyberfunk soundtrack memes, and here for one of the Ace Attorney x Danganronpa musical mashup channels on YouTube that Rebecca (and now Rachel too) is so very fond of.   Finally, as ever, are our current hyperfixations! Rebecca has discovered an accidentally awesome double-bill of horror novels with a timely social message in Chuck Tingle's Bury Your Gays and Grady Hendrix's The Final Girl Support Group; Liam's been having a whimsical time in recently-released indie platformer The Plucky Squire; and Rachel is having a moment with girly pop in general, and Chappell Roan and Sabrina Carpenter in particular, thanks to the recent VMAs award show.   Our music, meanwhile, was written and performed by Ollie Newbury! Find him on Instagram at @newbsmusic. Meanwhile, you can find us at indieventurepodcast.co.uk or wherever you listen to podcasts.  

Summary: Adam J Purcell, Andy Simpkins, Fake Keith and the Real Keith Dunn review the 1988 film Beetlejuice, the 2024 Doctor Who Prom and the recent Whooverville Doctor Who convention, find some general news and a variety of other stuff, specifically: 00:00 – Intro and theme tune. 01:19 — Welcome! 02:50 – News: 02:54 — […]

Hoppen, Franziska www.deutschlandfunkkultur.de, Studio 9

Connor, Harry & Luca Johnson discuss the Munich Muslim terror attack, the TENET Media Russian disinformation controversy, and the colonisation of the Proms.

The Doctor Who Proms FINALLY returned after 11 years away, and Troy went to the afternoon showing, and met Russell T Davies in the process! Join us as he walks you through the event - from the venue & music to the monsters & special guests, this episode's got it all...

Samira Ahmed talks to Pat Barker about the final part of her Troy trilogy, The Voyage Home. Alain Delon has died at the age of 88 - President Macron called him a French monument. Film critic Ginette Vincendeau assesses his impact on French film. At the Proms two orchestras are set to play works by Beethoven and Mozart from memory - conductor Nicholas Collon from the Aurora Orchestra explains how musicians manage without a score. And Orlando Weeks - formerly the frontman of Mercury Prize-nominated band The Maccabees - plays live in the studio and talks about the art he now creates, alongside music. Presenter: Samira Ahmed Producer: Paula McGrath

It's senior year at Enjoy Stuff! As our 4th season continues, the guys look back at everything involved in Enjoying senior year. Proms, yearbooks, graduations and more! Jay and Shua hope you have the time of your life on Enjoy Stuff!   We've seen your year, and it's gonna be awesome! After years of hard work, students around the world celebrate their final year of school by embracing their head honcho status. What can you enjoy senior year? Find out this week.    News Now you can stay at a Star Wars themed Air BnB Star Wars: Skeleton Crew premiere date has been revealed (and check out the teaser trailer) Did you watch Jim Henson Idea Man to Make making its broadcast debut on ABC? Warriors, come out to play-ee-ay! The classic movie is being reimagined as an album Only Murders in the Building is getting a board game The Orville Season 4 may actually begin production in early 2025 The Monster Cereals lineup will now include marshmallow pets Check out our TeePublic store for some enjoyable swag and all the latest fashion trends What we're Enjoying Shua is Enjoying a new late night show starring young comedienne Taylor Tomlinson called After Midnight. It's a pretend game show where comedians and celebrities answer goofy questions about the internet and modern day goings-on. Clips of the CBS show can be found on YouTube. Jay is watching the new Time Bandits homage created by Taika Waititi. It's only a few episodes in, so we are reserving judgment. It doesn't feel exactly like Terry Gilliam's original, but it is a cute story in it's own right. You can find Time Bandits on Apple TV+.   Sci-Fi Saturdays This week on Sci-Fi Saturdays Jay feels like he may have watched the movie before. 2006 Deja Vu is a time travel movie with a bit of a different point of view. Denzel Washington investigates a terrorist attack by looking back into the past. Check out all of Jay's articles on Sci-Fi Saturdays, only on RetroZap.com. And make sure to play around with the interactive map on MCULocationScout.com. There are some new locations from Agents of SHIELD season 3. Plus, you can tune in to SHIELD: Case Files where Jay and Shua talk about great stuff in the MCU.     Enjoy Senior Year!  It's the 4th season of Enjoy Stuff: A TechnoRetro Podcast! And that means that it's our Senior Year! So this week, in the wake of the beginning of school for many students, we look back at our High School Senior Year and a bunch of things we looked forward to in our final experience with public school. From senior pictures, proms, and graduations we hope that everyone's senior year was a celebration of a lot of years of hard work.    How was your senior year? What college should Jay and Shua apply to? First person that emails me with the subject line, “HAGS” will get a special mention on the show.  Let us know. Come talk to us in the Discord channel or send us an email to EnjoyStuff@RetroZap.com

It's senior year at Enjoy Stuff! As our 4th season continues, the guys look back at everything involved in Enjoying senior year. Proms, yearbooks, graduations and more! Jay and Shua hope you have the time of your life on Enjoy Stuff!

Tom Sutcliffe is joined by Rhianna Dhillon and Viv Groskop to review novel Echoes by Evie Wyld, which focuses on Max, a ghost who, stuck in the flat they had shared, watches his girlfriend grieving and discovers secrets about her. Pianist Benjamin Grosvenor talks about his upcoming performance of the longest concerto ever written, the Piano Concerto by Ferruccio Busoni, whose centenary is celebrated at this year's Proms. We'll also review the film Didi, a coming of age film set in 2008, focussing on a 13-year-old Taiwanese-American boy learning how to navigate life, love and family relations.Presenter: Tom Sutcliffe Producer: Corinna Jones

Tom talks to the creators of the hit Australian musical Fangirls, Yve Blake and Paige Rattray, as it opens in London. Countertenor Jakub Jozef Orlinski makes his Proms debut tomorrow night, and talks about combining his career as a top international soloist with breakdancing and modelling. Actor Samuel West discusses a new report from Campaign for the Arts, which reveals new findings about the state of the arts in the UK. Children's literature expert and broadcaster Bex Lindsay recommends summer books for younger children. Race to Imagination island: Mel Taylor Bessent The Nine night mystery: Sharna Jackson Super sunny murder club (collection) Mysteries at Sea: the royal jewel plot by AN Howell Ramzee: The cheat book Starminster: Megan Hopkins Fantastically great women, Sports stars and their stories: Pete PankhurstPresenter: Tom Sutcliffe Producer: Rebecca Stratford

Nancy Pelosi has become the latest leading democrat to back Kamala Harris after Joe Biden dropped out of the presidential race. We ask how she could fare with voters against Donald Trump.As the US considers electing its first Black woman as president, we get an insight into what Kamala Harris could bring to the job from the former Mayor of San Francisco who dated her when she was a young prosecutor 30 years ago. Also on the programme:The Conservatives have revealed their plans for electing the party's next leader - who won't be in post until November. We have the latest from Westminster.And, fresh from opening the Proms, the acclaimed pianist Isata Kanneh-Mason on her call for the government to back music in schools.

Is it Cherio, Joe? With speculation in the United States that the president could pull out of the presidential campaign as soon as this weekend, we ask a former aide to Kamala Harris, the vice president, about what a ticket led by her could be like.Also on the programme:As the world grapples with the effects of what's been called the worst IT outage ever - just how fragile is the fabric of our digital world? A government advisor on why he's waging war on "ugly" phone boxes blighting Britain's streets.And we speak to the 27-year-old musician who wrote the video game-inspired composition which premiered at this evening's First Night of the Proms.

Hattie Butterworth meets soprano Sophie Bevan ahead of her appearance at the First Night of the Proms. Moving through Sophie's early life and career, they speak about her experience navigating a diagnosis of bowel cancer, the importance of her faith and family, and what she wishes audiences knew about the life of a singer.  Music included in the epsiode: 'Take the Heart' from Jephtha Act I, Scene 3: George Friderich Handel · The Sixteen · Harry Christophers on CORO (2014) 'Perché, se tanti siete' from Scena di Berenic on Perfido!  · Sophie Bevan · Franz Joseph Haydn · Ian Page · Classical Opera / The Mozartists on Signum Classics (2017) 'Ferma l'ali' from Pt. 1 Scene 2 from Handel's La Resurrezione · The English Concert · Harry Bicket · Sophie Bevan on Linn Records (2023) 'Beati Quorum Via' by Charles Villiers Stanford from Vidi Speciosam: Sacred Choral Music · Graham Ross · The Bevan Family Consort  on Signum Records (2023)    

Joe went to an Ibiza Proms concert on Brighton beach at the weekend and David wants to know everything about it. Unsurprisingly, Joe wasn't in his comfort zone for most of the event - and even popped home to watch some football for a few hours. So David digs in for more information and enjoys every minute of Joe's squirming. Plus, there's some chat about DJing, a tale about meeting a millionaire and an update on the long awaited stag-do that David's just returned from. FOR ALL THINGS CHATABIX'Y FOLLOW/SUBSCRIBE/CONTACT: You Tube: https://www.youtube.com/@chatabixpodcast Twitter: https://twitter.com/chatabix1 Insta: https://www.instagram.com/chatabixpodcast/ Patreon: https://www.patreon.com/chatabix Merch: https://chatabixshop.com/ Contact us: chatabix@yahoo.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

As Disco makes its debut at the Proms, conductor Daniel Bartholomew-Poyser, who will be leading the BBC Concert Orchestra at Saturday's Everybody Dance! The Sound of Disco Prom, talks about the link between the music which dominated the 1970s pop charts and the orchestral world.Today the Welsh First Minister, Vaughan Gething and four of his cabinet ministers including the Culture Secretary resigned. Jane Henderson, President of The Federation of Museums and Art Galleries of Wales, and Emma Schofield, Editor of Wales Arts Review, discuss the current arts funding crisis in Wales and the impact of the political upheaval.Sweet Dreams is a new immersive installation at Aviva Studios in Manchester which explores our relationship with fast food. It's been created by cutting edge arts collective Marshmallow Laser Feast, and the group's co-founder and director, Robin McNicholas, talks to Nick about fusing theatre, gaming, and video art to tell new stories.Pioneering artist Bill Viola, who was known for his distinctive slow motion videos which reflected on life's biggest questions, is remembered by Marshmallow Laser Feast director, Robin McNicholas. We also delve into the Front Row archives to hear Viola himself talk about how a "miracle" inspired his installation in St Paul's Cathedral. Presenter: Nick Ahad Producer: Ekene Akalawu

On today's show, prom season is upon us and we're going back in our memory vault for prom memories. Were promposals a thing when you were in school? Did your prom live up to your expectations?? For the whole podcast, as well as a ton of other exclusive perks, sign up to be a Fancy Idiot at FreeBeerAndHotWings.com! Hosted on Acast. See acast.com/privacy for more information.

On today's show, prom season is upon us and we're going back in our memory vault for prom memories. Were promposals a thing when you were in school? Did your prom live up to your expectations?? For the whole podcast, as well as a ton of other exclusive perks, sign up to be a Fancy Idiot at FreeBeerAndHotWings.com! Hosted on Acast. See acast.com/privacy for more information.

1. PROMs after surgical evacuation of spinal epidural hematoma 2. ERAS in cervical spinal deformity surgery

Episode 299 of The Pour Horsemen Podcast! We Pod Solo!TopicsTerrence Howard Brilliant or FraudECF and WCF NBA FInalsBBL DrizzyProms are Out of Control And More Hurt At Work? Contact our partners at https://crockett.law for all of your legal needs. @bankonbriantx is ready to help. Join our Patreon for more exclusive content: https://www.patreon.com/thepourhorsemen By supporting us, you're not just a listener but a valued part of our community. Use our Code POUR at Bluechew.com for your discount. Follow The Pour Horsemen on Instagram @thepourhorsemen and email at thepourhorsemen@gmail.com. Subscribe to Apple Podcast, Spotify Podcast, Google Play, YouTube, iHeartradio, or PocketCast.

SynopsisToday's date in 1879 marks the birthdate of composer and pianist Régine Wieniawski, born in Brussels, the daughter of the Polish violinist and composer Henryk Wieniawski. Although a Franco-Belgian composer in style, she published her music under the Slavic-sounding pen name Poldowski. She was admired by many of the most famous musicians of her day. Henry Wood programmed her works on Proms concerts, and in 1912, she gave a concert at London's Aeolian Hall, that, quite unusual for the time, consisted solely of her own works with the her at the piano. That concert introduced 24 of her songs, many to texts of French poet Paul Verlaine. The review in the Daily Telegraph noted, “nearly every song was a distinguished example of the art of word setting; and the sense of harmonic color is decidedly strong.” The performance of her Violin Sonata, also on the program, was not as well received; the London Times sniffed, “the method which was successful in the songs was less effective in the Violin Sonata.”Oh well, Poldowski's Verlaine settings are still very much admired and performed, and her instrumental music, neglected for decades, is also getting renewed attention.Music Played in Today's ProgramRégine Wieniawski (aka Poldowski) (1879-1932): Scherzo from Violin Sonata; Clare Howick, violin; Miroslaw Feldgebel, piano; Dux 1840

0:00 Intro4:30 Inbreeding9:00 Calendar19:00 Upcoming Elections23:00 Rudolph Steiner50:00 King Charles IV52:00 Judiciary Abuse1:04:00 Privateer1:13:00 Greek ConvertSupport the Show.

This week, we kick off with some app-exclusive deals in the Jungle Jim's app. It's now available on iOS and Android! Don't forget about our Eclipse Event on April 8th. Then we meet store manager Frank's daughter Yolanda and her husband Lamar to talk about their band Live Your Dream, as well as talk about her upcoming performances for the Cincinnati Reds! Maybe she'll even sing for us! Then, Zachariah from Urban Artifact comes over to talk about Urban's new beer, Capy Snacks, a delicious fruit punch sour, as well as their upcoming Faerie Ball/Fruit Prom, hosted by me! What a great week!

3 - 5-24 WHO WENT TO THE MOST PROMS by Maine's Coast 93.1

Sheku Kanneh-Mason is a cellist who came to international attention when he performed at the wedding of Prince Harry and Meghan Markle in 2018. Still only 24, he has performed at a series of high profile locations including the Hollywood Bowl and Downing Street. Last year he was a soloist at the Last Night of the Proms. Sheku was brought up in Nottingham along with his six siblings who are also extremely talented musicians. At six-years-old he went to a concert by the Nottingham Youth Orchestra where he was transfixed by the cello section. He started having lessons not long afterwards and by the age of nine he'd completed all of his music grades – receiving the highest marks in the country. At 17 he won the BBC Young Musician of the Year competition.He went on to study at the Royal Academy of Music and made his debut at the BBC Proms as a soloist with the Chineke! Orchestra in 2017.In 2020 he was appointed an MBE for services to music and two years later became the Royal Academy of Music's first Menuhin Visiting Professor of Performance Mentoring.DISC ONE: Cello Concerto in E minor, Op.85 - 1st movement: Adagio – Moderato. Composed by Edward Elgar and performed by Jacqueline du Pré, with the London Symphony Orchestra, conducted by Sir John Barbirolli DISC TWO: Rivers of Babylon -The Melodians DISC THREE: Dat - Pluto Shervington DISC FOUR: String Quartet in C major, Op 20 No. 2, Capriccio: Adagio. Composed by Joseph Haydn and performed by The London Haydn Quartet DISC FIVE: Chances Are - Bob Marley DISC SIX: Requiem in D minor, K. 626 , Introitus 1 – Requiem. Composed by Wolfgang Amadeus Mozart and performed by the Monteverdi Choir DISC SEVEN: Symphony No.11 'The Year 1905' - II. The 9th January; Adagio. Composed by Dmitri Shostakovich and performed by The Moscow Philharmonic, conducted by Kirill Kondrashin DISC EIGHT: Largo from Organ Sonata No.5 in C major, BWV 529. Composed by Johan Sebastian Bach and performed by Samuel FeinbergBook: The Feynman Lectures on Physics by Richard Feynman Luxury: A cello and strings CASTAWAY'S FAVOURITE: Requiem in D minor, K. 626 , Introitus 1 – Requiem. Composed by Wolfgang Amadeus Mozart and performed by the Monteverdi ChoirPresenter Lauren Laverne Producer Paula McGinley