Podcasts about osteogenesis

In this episode of the Gladden Longevity Podcast, Kyle Zagrodsky discusses his journey with OsteoStrong, a company dedicated to reversing bone density loss. The conversation explores the importance of fear and courage in personal growth, the science behind OsteoStrong's innovative equipment, and the significant impact of bone health on overall well-being. Kyle shares success stories from users of OsteoStrong, emphasizing the potential for rebuilding bone density and improving quality of life. The episode concludes with Kyle's vision for the future of OsteoStrong and its mission to eliminate osteoporosis globally.    FOR THE AUDIENCE  Empower your life with the ULTIMATE longevity solution → https://www.osteostrong.me/  Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/ !    Takeaways    Fear can be a guiding principle in life.  Courage is essential for living authentically.  Osteoporosis is a significant health concern.  Bone density affects overall health and longevity.  OsteoStrong's equipment is designed for maximum impact and it's safer than walking.  High impact forces are necessary for bone regeneration.  Success stories highlight the effectiveness of OsteoStrong.  Integrating nutrition and hormone optimization enhances results.  OsteoStrong aims to make bone health accessible to all ages.  The future goal is to eliminate osteoporosis worldwide.    Chapters    00:00 Introduction to OsteoStrong and Personal Journey  04:08 Fear as a Compass: Overcoming Challenges  07:26 The Importance of Courage in Life Decisions  10:13 Understanding Bone Health and OsteoStrong  13:08 The Science Behind OsteoStrong's Technology  16:18 The Interplay Between Bone Density and Athletic Performance  19:19 Holistic Approaches to Bone Health  22:29 Results and Success Stories from OsteoStrong  28:20 Understanding Bone Density and DEXA Scans  33:43 The OsteoStrong Experience: How It Works  35:49 Innovative Equipment for Bone Health  41:08 Long-Term Goals: Combating Osteoporosis  43:23 Safety and Contraindications in OsteoStrong Training  47:09 The Broader Impact of OsteoStrong  49:52 Goodbye    To learn more about OsteoStrong:  Website: https://www.osteostrong.me/   Facebook: https://www.facebook.com/osteostrong   Instagram: https://www.instagram.com/iamosteostrong/   X: https://twitter.com/OsteoStrong   YouTube: https://www.youtube.com/user/osteostrong     Reach out to us at:     Website: https://gladdenlongevity.com/      Facebook: https://www.facebook.com/Gladdenlongevity/     Instagram: https://www.instagram.com/gladdenlongevity/?hl=en      LinkedIn: https://www.linkedin.com/company/gladdenlongevity     YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw     

Gaelynn Lea is a professional musician and sought-after public speaker. She has opened for numerous artists including the Decembrists, composed the music for Macbeth on Broadway, starring Daniel Craig, and her perspectives have been shared on outlets such as On Being With Krista Tippett and PBS NewsHour.Having been born with Osteogenesis imperfecta, or brittle bone disease, Gaelynn has had to navigate the world differently. Such life experiences have shaped her perspectives in important in meaningful ways, including becoming an advocate for Disability Rights and Accessibility. In our time together, Gaelynn shares about the beautiful insight that disability can bring, as well as her passion for increased education about disability. She also discusses the transcendence of music, how she is able to hold life's beauty and pain, and how she broke free from lies associated with societal beauty.Gaelynn Lea is an incredibly talented musician, and she is so much more than that. She invites us all to take a deeper look at life, what it's ultimately about, and the kind of beauty that is truly worth pursuing.To watch Gaelynn's TED Talk, go here. Buy Melissa L. Johnson's book, Soul-Deep Beauty: Fighting for Our True Worth in a World Demanding Flawless, here. Learn more about Impossible Beauty and join the community here.

A big part of learning about pediatrics is understanding different musculoskeletal disorders in children. Rather than going through each of these using the full Straight A Nursing LATTE method, I've provided a concise summary of a wide range of conditions: * Soft tissue injuries and fractures * Developmental dysplasia of the hip (DDH) * Skeletal limb deficiencies * Osteogenesis imperfecta * Legg-Calve-Perthes * Slipped capital femoral epiphysis * Spinal curvature disorders * Juvenile idiopathic arthritis * Achondroplasia * Osteochondroma and osteosarcoma * And more! You can read this information and view references in the articles "Pediatric Soft Tissue Injuries and Fractures" and "Musculoskeletal Disorders in Children". Review pediatric topics on the go with Study Sesh! Study for your nursing school exams and NCLEX on the go with over 90 PodQuiz episodes covering a wide range of topics. Sign up for Study Sesh here! __________  The information, including but not limited to, audio, video, text, and graphics contained on this podcast are for educational purposes only. No content on this podcast is intended to guide nursing practice and does not supersede any individual healthcare provider's scope of practice or any nursing school curriculum. Additionally, no content on this podcast is intended to be a substitute for professional medical advice, diagnosis or treatment. Straight a Nursing is a proud member of the Airwave Media Network. Learn more about your ad choices. Visit megaphone.fm/adchoices

(3:00) - 3D printing with bacteria-loaded ink produces bone-like compositesThis episode was brought to you by Mouser, our favorite place to get electronics parts for any project, whether it be a hobby at home or a prototype for work. Click HERE to learn about how additive manufacturing is being leveraged in the medical industry from bone replacement to dental guides!

 Katherine Klimitas is an artist and graphicdesigner who has osteogenesis imperfecta. She has been painting since she wasfive and sells her work, mostly watercolor paintings of animals. She also doesbranding design, business cards, logos, letterhead, websites, and social mediamanagement. She has worked with high-profile people such as Rod Stewart andencourages people to find something they can contribute to society. Her websiteis kakartnola.com, and she can be found on social media as @kakartnola.     Action Items     1. Buy brushes on Black Friday.  2. Complete paintings in two to five days.  3. Create pet portraits, graphic design,public speaking, and jewelry design.  4. Promote the website (kakartnola.com) andsocial media (@kakartnola).  5. Encourage people to find something tocontribute to society and put in the effort.     Bio  Katherine Klimitas is a New Orleans-basedartist and designer who sold her first watercolor at age 10. As the daughter ofveterinarians, Katherine expresses her family's lifelong love of animalsthrough her meticulous life-like paintings. She earned a B.A. from LoyolaUniversity in 2011; at age 33, she runs her multifaceted business, KAK ART& Designs, from home. When clients learn that Katherine has OsteogenesisImperfecta, also known as brittle bone disease, they are captivated by herunique perspective. She and her parents stopped counting her broken bones at500 at age 10. She's 2 feet 7 inches tall, gets around in an electricwheelchair, and creates all her art, jewelry, and commercial graphic design whilelying on her side.     Links   kklimitas@gmail.com  https://www.youtube.com/channel/UCVRhBQ4oHeLhhN5t33JxZOg      https://www.linkedin.com/in/katherineklimitas      https://www.facebook.com/kakartnola      https://www.instagram.com/kakartnola      https://kakartnola.com        

Gary Patti was born with Osteogenesis imperfecta. A life of about 100 fractures with first coming at 2 weeks old. He competed in various wheelchair sports, basketball and track events. Ranked 3rd in the world at the mile event in 1978. 43 years in the fitness industry owning numerous Health and Fitness Clubs. International motivational, inspirational and business speaker Gary stand's tall being a little over 4' 1".

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.09.519810v1?rss=1 Authors: Doherty, L., Wan, M., Peterson, A., Youngstrom, D. W., King, J. S., Kalajzic, I., Hankenson, K. D., Sanjay, A. Abstract: Despite the remarkable regenerative capacity of skeletal tissues, nonunion of bone and failure of fractures to heal properly presents a significant clinical concern. Stem and progenitor cells are present in bone and become activated following injury; thus, elucidating mechanisms that promote adult stem cell-mediated healing is important. Wnt-associated adult stem marker Lgr6 is implicated in the regeneration of tissues with well-defined stem cell niches in stem cell-reliant organs. Here, we demonstrate that Lgr6 is dynamically expressed in osteoprogenitors in response to fracture injury. Using an Lgr6-null mouse model, we find that Lgr6 expression is necessary for maintaining bone volume and efficient postnatal bone regeneration in adult mice. Skeletal progenitors isolated from Lgr6-null mice have reduced colony-forming potential and reduced osteogenic differentiation capacity due to attenuated cWnt signaling. Lgr6-null mice consist of a lower proportion of self-renewing stem cells. In response to fracture injury, Lgr6-null mice have deficient proliferation of periosteal progenitors and reduced ALP activity. Further, analysis of bone regeneration phase and remodeling phase of fracture healing in Lgr6-null mice showed impaired endochondral ossification and reduced mineralization. We propose that in contrast to not being required for successful skeletal development Lgr6-positive cells have a direct role in endochondral bone repair. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

This episode features a discussion of nasalance and speech outcomes between first author and speech therapist, Eshan Schlief, and a multi-disciplinary panel including speech therapist Liza Catallozzi, plastic surgeon Gregory Pearson, oral-maxillofacial fellow Pasha Shakoori, and plastic surgery resident Naikhoba Munabi. Read the article here.

Gary Patti was born with Osteogenesis imperfecta. A life of about 100 fractures with first coming at 2 weeks old. He competed in various wheelchair sports, basketball and track events. Ranked 3rd in the world at the mile event in 1978. 43 years in the fitness industry owning numerous Health and Fitness Clubs. International motivational, inspirational and business speaker.  

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.10.23.513322v1?rss=1 Authors: Chen, X., Rong, K., Han, W., Pang, Y., Chai, G. Abstract: In previous research, miR-148a-3p deficiency was observed in bone malformation in hemifacial microsomia. Herein, in this article, we probed into the role of miR-148a-3p in bone physiology by utilizing miR-148a knock-out (KO) mice. Compared with wild-type (WT) or heterozygotic (HE) littermates, miR-148a knock-out mice manifested lower body weight, bone dysplasia with increased bone mass. Through in-vitro experiments, in terms of miR-148a-3p overexpression (miRNA mimic transfection) and knockout (primary cells from WT and KO littermates), we found that miR-148a-3p can suppress osteogenesis, either in the ALP activity or bone nodules formation. Afterward, by means of proteomics, combined with RNA-sequencing and prediction databases of microRNA targets (miRDB and TargetScan), nine candidate genes targeted by miR-148a-3p were identified. Among them, only Itga11 was regulated by mRNA degradation, while the others were modulated via post-transcriptional inhibition. Based on several online databases (GenePaint, BioGPS, STRING), Integrin Subunit Alpha 11 (Itga11) was suggested to play an essential role in osteogenesis and it was confirmed as one direct target of miR-148a-3p by dual-luciferase reporter assay. Meanwhile, gene set enrichment analysis (GSEA) indicated activation of PI3K-Akt signaling pathway and WNT signaling pathway in miR-148a KO mice. The thereafter western blot confirmed that PI3K/Akt/GSK3/{beta}-catenin signaling pathway was involved. Taken together, we demonstrated that miR-148a-3p can inhibit osteogenesis by targeting Itga11 via PI3K/Akt/GSK3/{beta}-catenin pathway. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

In this episode of the Epigenetics Podcast, we caught up with Susanne Mandrup from the University of Southern Denmark to talk about her work on the role of enhancer communities in adipocyte differentiation. The Laboratory of Susanne Mandrup focuses on the effect of enhancers and enhancer communities on the differentiation of mesenchymal stem cell into adipocytes and osteoblasts. The team has shown that there is significant cross-talk between enhancers and that these form communities of highly interconnected enhancers. Inactive enhancers are then activated by association with these pre-existing enhancer networks to facilitate gene expression in adipocyte differentiation.   References Siersbæk R, Rabiee A, Nielsen R, Sidoli S, Traynor S, Loft A, Poulsen LC, Rogowska-Wrzesinska A, Jensen ON, Mandrup S. Transcription factor cooperativity in early adipogenic hotspots and super-enhancers. Cell Rep. 2014 Jun 12;7(5):1443-1455. doi: 10.1016/j.celrep.2014.04.042. Epub 2014 May 22. PMID: 24857652. Siersbæk R, Baek S, Rabiee A, Nielsen R, Traynor S, Clark N, Sandelin A, Jensen ON, Sung MH, Hager GL, Mandrup S. Molecular architecture of transcription factor hotspots in early adipogenesis. Cell Rep. 2014 Jun 12;7(5):1434-1442. doi: 10.1016/j.celrep.2014.04.043. Epub 2014 May 22. PMID: 24857666; PMCID: PMC6360525. Siersbæk R, Madsen JGS, Javierre BM, Nielsen R, Bagge EK, Cairns J, Wingett SW, Traynor S, Spivakov M, Fraser P, Mandrup S. Dynamic Rewiring of Promoter-Anchored Chromatin Loops during Adipocyte Differentiation. Mol Cell. 2017 May 4;66(3):420-435.e5. doi: 10.1016/j.molcel.2017.04.010. PMID: 28475875. Rauch, A., Haakonsson, A.K., Madsen, J.G.S. et al. Osteogenesis depends on commissioning of a network of stem cell transcription factors that act as repressors of adipogenesis. Nat Genet 51, 716–727 (2019). https://doi.org/10.1038/s41588-019-0359-1 Madsen, J.G.S., Madsen, M.S., Rauch, A. et al. Highly interconnected enhancer communities control lineage-determining genes in human mesenchymal stem cells. Nat Genet 52, 1227–1238 (2020). https://doi.org/10.1038/s41588-020-0709-z   Related Episodes Ultraconserved Enhancers and Enhancer Redundancy (Diane Dickel) Effects of DNA Methylation on Diabetes (Charlotte Ling) Epigenetic Regulation of Stem Cell Self-Renewal and Differentiation (Peggy Goodell)   Contact Active Motif on Twitter Epigenetics Podcast on Twitter Active Motif on LinkedIn Active Motif on Facebook Email: podcast@activemotif.com

Roe v. Wade, Osteogenesis imperfecta, EMDR therapy. Dave returns to chat with Celeste about staying connected with your partner, including shower meetings, holding hands, and good TV. Advocate Kelsey Walker joins Celeste in an emotional conversation sharing her experience with abortion, advocating for reproductive rights at the Supreme Court, and detailing how her non-profit supports people through abortions, miscarriage and pregnancy loss.  From the Green Desk Website Shout Your Abortion Website Celeste Busa IG Dave Hill IG THE SHOW: Please rate and review the show on iTunes. It helps the show grow and be discovered. Follow WEEK BY WEEK on Instagram, @weekbyweekpodcast Check out our playlist on YouTube Browse our blog at weekbyweekpodcast.com You can contact us at WeekByWeekShow@gmail.com © 2022 Gumption Pictures

About this Episode Today on the show Heather is talking with Katherine Klimitas. Katherine is an author, speaker, artist, and graphic designer. She also happens to have Osteogenesis imperfecta also known as brittle bone disease. By the time she was 10 years old she had already broken 500 bones, so she knows a thing or two about adversity, diversity, adaptability, and resilience. Katherine, welcome to the show! Connect with Us: Website: https://diversityonfire.com/ Facebook Group: https://www.facebook.com/groups/diversityonfire Instagram: https://www.instagram.com/diversityonfire/ Twitter: https://twitter.com/diversityonfire Facebook: https://www.facebook.com/Diversityfire Heather: https://www.instagram.com/hponfire/ Guest/Episode Links: https://kakartnola.com/ Podcast: Subscribe: https://anchor.fm/diversityonfire - All Platforms Voicenote: https://anchor.fm/diversityonfire/message --- Send in a voice message: https://anchor.fm/diversityonfire/message

Katherine has Osteogenesis imperfecta, or brittle bone syndrome, which causes her bones to break quite easily and also made it so they did not form fully. x She tells of her days growing up with some funny anecdotes that you would never think about unless you lived them. x Katherine also tells about her art and the way she gets her art done, and it is really amazing! x She is a truly beautiful human, and I am so glad I was able to speak with her! x Connect with Katherine at... https://kakartnola.com/ x Enjoy this conversation. x Peace Signs Up ✌

Sammi Haney RETURNS!***THIS IS PART OF MY RAISING DION SEASON 2 WEEK-LONG PODCASTING EVENT***Take a walk with me down Fascination Street as I get to know even more about return guest Sammi Haney. This is Sammi's second appearance on the show, and she holds the record for being the youngest guest ever to appear on Fascination Street Podcast. Sammi is an actress and inspiration. She plays Esperanza on Netflix's Raising Dion, which just released their second season. In this episode we chat about Sammi, Ja'Siah (Dion), and Gavin (Johnathan) playing on the set, and getting up to shenanigans when they aren't working. We also talk about how much she is looking forward to season two. Sammi tells us how she spent her Covid, about some recent surgeries, and her new pet! We also have some laughs about how much fun it is to work on Raising Dion and to be best friends with the other kids on the show. I mean they all play Minecraft together!Obviously there are no spoilers for season two; but go back and watch season one if you haven't. Special thanks to Sammi's parents Matt and Priscilla for once again making this happen. Follow Sammi on social media:Insta: @SammiHaneyFB: Disability ShirtsCheck out her website: DisabilityShirts.com

Kip Mangira was a Cutco Sales Professional in Vector Marketing's Midwest Region. He was born on September 2nd, 1995, in Akron, Ohio, with Osteogenesis imperfecta (brittle-bone disease), which confined him to a wheelchair for his entire life. Still, he had an indomitable spirit, and was not afraid to take on the challenge of selling Cutco Cutlery, starting in 2013. He won numerous awards for his exemplary work ethic and sales success, including the Silver Cup for finishing #1 in the Nation in sales in his competitive category in 2019. Known for his generosity and compassion, Kip became of the most-loved figures in the Cutco/Vector sales organization. He passed away on November 9th, 2021 in a road accident in Cozumel, Mexico. Kip Mangira was too well-loved to ever be forgotten. Region Manager Jeff Bry hosts this special tribute episode featuring Kip's brother, Stephen, and some of Kip's closest Cutco colleagues. To get access to all episodes and free resources, visit  ChangingLivesPodcast.com.

FROM THIS EPISODEOsteogenesis Imperfecta Osteogenesis imperfecta (OI) is an inherited (genetic) bone disorder that is present at birth. It is also known as brittle bone disease. https://www.hopkinsmedicine.org/health/conditions-and-diseases/osteogenesis-imperfecta Skeletal DisplaysiaSkeletal dysplasia is the medical term for a group of about 400 conditions that affect bone development, neurological function, and cartilage growth, including its most common form, achondroplasia.https://www.hopkinsmedicine.org/health/conditions-and-diseases/skeletal-dysplasia AchondroplasiaAchondroplasia is a form of short-limbed dwarfism. The word achondroplasia literally means "without cartilage formation." https://medlineplus.gov/genetics/condition/achondroplasia/ Little People of Americahttps://www.lpaonline.org The Missing Piece – Animated Shel Silverstein:https://www.youtube.com/watch?v=4gEjCJOzqXc The Cracked Pot Children's Storyhttps://alltimeshortstories.com/life-the-cracked-pot/ Crip Camp: The Filmhttps://www.youtube.com/watch?v=XRrIs22plz0 Crip Camp: The Revolutionhttps://cripcamp.com FINDING JILLIAN Podcast: https://podcasts.apple.com/us/podcast/always-looking-up/id1567615385Instagram:@jill_ilana, @alwayslookingup.podcastWebsite:https://www.jillianilana.comEmail:alwayslookingup227@gmail.com

The Living Full Out Show encourages you to create a legacy. Maybe you want to set an example of responsibility to your family. Perhaps you want to start a successful career or business. Building a legacy can be defined as what you have accomplished or how you treat others. Discovering your purpose and what you want to create, paves the way to achieving your goals and aspirations.Our first caller, Sarah, wants to know how she can stay motivated to complete her therapy exercises. Nancy advises Sarah to think back to the moments when she regretted not doing the physical therapy. Nancy also recommends that Sarah puts together a consequence for herself when she fails to do her exercises. Tune in to hear how you can change your mindset in order to accomplish something.Our inspirational guest, Hannah Elizabeth, has been in a wheelchair since she was two years old. She was born with Osteogenesis imperfecta, a genetic disorder that affects her bones and causes them to break easily. Despite the challenges Hannah faces everyday, she always strives to look on the positive side and focus on her abilities rather than what she is unable to do. Hannah was able to discover her passion for beauty and started her own successful makeup youtube channel. Listen in to hear how Hannah uses her talents and optimism to create a legacy and accomplish her dreams.Our final caller, Eric, wants to know how he can stay positive during the pandemic, without worrying so much about the future. Nancy recommends that Eric embrace the moment and utilize this time to spend with his family. Nancy also reminds Eric to be grateful for the gifts he has at this present time and not to dwell on the “what ifs.” Tune in to hear how you can live for today and worry less.Maybe you strive to be honest and empathetic to everyone you meet. Perhaps you want to become an expertise in a cause you are passionate about. Remember that building a legacy doesn't have to be alone. You can have a support group or team to help you achieve your goals. By creating a legacy that allows you to better serve others, as well as improving yourself, is essential to living full out!

A study by Stanley Yung-Chuan Liu, Christian Guilleminault, Leh-Kiong Huon, Audrey Yoon found that Objective Distraction osteogenesis maxillary expansion (DOME) is a reliable method to expand the nasal floor and hard palatal vault in adults with obstructive sleep apnea (OSA). DOME results in a reduction in the apnea-hypopnea index (AHI) and subjective report of improved nasal breathing.A narrow maxilla with high arched palate characterizes a phenotype of obstructive sleep apnea (OSA) patients that is associated with increased nasal resistance and posterior tongue displacement. Current maxillary expansion techniques for adults are designed to correct dentofacial deformity. We describe distraction osteogenesis maxillary expansion (DOME) tailored to adult patients with OSA with narrow nasal floor and high arched palate without soft tissue redundancy. DOME is performed with placement of maxillary expanders secured by mini-implants along the midpalatal suture. This minimizes the maxillary osteotomies necessary to re-create sutural separation for reliable expansion at the nasal floor and palatal vault. We report the safety and efficacy profile of the first 20 patients at Stanford who underwent DOME.Airway and Sleep group employs the DOME technique for improving airway and combatting the effects of obstructive sleep apnea. Schedule a consultation to develop a strategic plan for airway improvement by calling 571.244.7329.

A study by Stanley Yung-Chuan Liu, Christian Guilleminault, Leh-Kiong Huon, Audrey Yoon found that Objective Distraction osteogenesis maxillary expansion (DOME) is a reliable method to expand the nasal floor and hard palatal vault in adults with obstructive sleep apnea (OSA). DOME results in a reduction in the apnea-hypopnea index (AHI) and subjective report of improved nasal breathing.A narrow maxilla with high arched palate characterizes a phenotype of obstructive sleep apnea (OSA) patients that is associated with increased nasal resistance and posterior tongue displacement. Current maxillary expansion techniques for adults are designed to correct dentofacial deformity. We describe distraction osteogenesis maxillary expansion (DOME) tailored to adult patients with OSA with narrow nasal floor and high arched palate without soft tissue redundancy. DOME is performed with placement of maxillary expanders secured by mini-implants along the midpalatal suture. This minimizes the maxillary osteotomies necessary to re-create sutural separation for reliable expansion at the nasal floor and palatal vault. We report the safety and efficacy profile of the first 20 patients at Stanford who underwent DOME.Airway and Sleep group employs the DOME technique for improving airway and combatting the effects of obstructive sleep apnea. Schedule a consultation to develop a strategic plan for airway improvement by calling 703-646-9950.

One of my favorite people that I have ever worked with and I have worked with thousands of people. Steve Hlushuk (Shooky) is the epitome of a positive minded person and that is really so important in life. We worked together for about 5 years in the early 2000's and he was always happy, sharp and one of the funniest dudes I have ever met. We discuss Bigfoot losers, his cool as shit car, the difference of a positive attitude, his favorite cocktail, his proficiency in JD Edwards, being a good parent in a challenging world, Osteogenesis imperfecta and how it does not slow him down! and how he was WAY ahead of his time with short "Tic-Toc-ish" videos (There is still time to go viral!!) along with several other topics and maybe even a Robert De Niro impersonation...little bit? Thank you very much for being on the Podcast and I hope you all enjoyed the conversation as much as we did!

Doctor Dating Game: Joe Balewski“What you have to look for in a doctor is not somebody who gives you the diagnosis that you want. It’s finding the doctor who listens.” – Joe BalewskiAbout Joe: Eva was joined this week by Joe Balewski. Joe is no stranger to the healthcare system - he has a lifetime of experience with Osteogenesis Imperfecta and, most recently, 13 years with Postural Orthostatic Tachycardia Syndrome. This past year, Joe started a practical chronic illness podcast called THE CHRONIC ILLNESS PLAYBOOK where he interviews Spoonies about the practices that get them through the day.In this episode, Joe and Eva discuss:The doctor-patient “Dating game”The importance of having human interactions with your doctorThe path to getting a diagnosis (With POTS) Timestamps:07:15 The trial and error period of your first diagnosis15:00 What started “The Chronic Illness playbook”26:15 Getting diagnosed with Osteogenesis 54:24 The similarities of the doctor-patient relationship and a romantic relationship1:16:07 The reality of finding a good doctorJoe’s links: Instagram: @chronicillnessplaybook Facebook: @ChronicIllnessResourceGuideBonus questions:What are your top 3 tips for someone who is undiagnosed but they know that something is “off”? Listen to your body; Take notes; Be patient.If you could have a giant billboard, metaphorically speaking, that could get a message out to millions or billions of people, what would it say and why? It could be a few words, a sentence or a few. It can be your quote or, if helpful, someone else’s quote. (i.e. Is there any quote you think of often or live your life by?)“Motivation is fleeting. Fall in love with the process.” CLICK HERE FOR FULL TRANSCRIPT. PLEASE SUPPORT US BY: SHARING WITH LOVED ONES

Nick Chase is a Freshman at Virginia Tech studying political science. He enjoys listening to music, shopping at local thrift stores, and playing video games with friends. During today's episode, Nick shares with us his experience with Osteogenesis Imperfecta, a rare bone disorder resulting from a lack of collagen. He tells us about his perspective as someone with a disability and what that has looked like in his life. Nick had this to say about his experience on the Disability Perspectives Podcast: "Being on The Disability Perspectives Podcast was a fun, relaxed conversation with my roommate! I hope that people can learn more about OI, learn not to judge by appearance, and learn to advocate for themselves from my perspective on things." Links for this episode: https://www.hopkinsmedicine.org/health/conditions-and-diseases/osteogenesis-imperfecta#:~:text=Osteogenesis%20imperfecta%20(OI)%20is%20an,formed%20normally%2C%20and%20other%20problems. --------------------------- Thank you for listening to the Disability Perspectives Podcast! We are working on creating a space to share all of our episode transcripts so that the Disability Perspectives Podcast is accessible to everyone. Until that is available, if you would like access to the transcript for any episode, please send us an email at disability.perspectives@gmail.com and we will be happy to share them with you! If you or anyone you know is interested in being a part of the podcast as a guest, contributor, or team member, please fill out this google form: https://forms.gle/TiitPVCGfanPX9vf8 If you have any questions or would like to reach out to us for any reason or discuss supporting us financially to offset production costs, please email us at disability.perspectives@gmail.com Find us online at anchor.fm/utah-kershner1 Please follow our social media accounts and share us with your friends! Facebook: @disability.perspectives Instagram: @disability.perspectives Twitter: @DP_podcast1 --------------------------- Host: Utah Kershner Audio editing/production: Scotty Larsen Marketing/Social Media/Creativity: Polina Sobol & Morgan Rader Find the Disability Perspectives Podcast wherever you get your podcasts!

We sit down and talk with James, who resides in Acworth, GA and lives with a number of chronic illnesses. James suffers from hyper-mobility spectrum disorder, POTS syndrome, and Osteogenesis imperfecta. Throughout the hour, we dive into the early stages of his diagnosis, what every day life is like with these conditions, his experience with the medical system, and the problem with employer based insurance. Be sure to like us on Facebook, follow us on Twitter, and subscribe to this show wherever you get your podcasts. If you more than liked it and would like to support the ongoing production of content like this, consider becoming a supporter on Anchor.fm. And as always, a thank you to Rachel Palmer for the music featured throughout this episode. Go check out her work at rachelpalmer.bandcamp.com. --- Send in a voice message: https://anchor.fm/leftinthebasement/message Support this podcast: https://anchor.fm/leftinthebasement/support

The Living Full Out Show encourages you to create a legacy. Maybe you want to set an example of responsibility to your family. Perhaps you want to start a successful career or business. Building a legacy can be defined as what you have accomplished or how you treat others. Discovering your purpose and what you want to create, paves the way to achieving your goals and aspirations. Our first caller, Sarah, wants to know how she can stay motivated to complete her therapy exercises. Nancy advises Sarah to think back to the moments when she regretted not doing the physical therapy. Nancy also recommends that Sarah puts together a consequence for herself when she fails to do her exercises. Tune in to hear how you can change your mindset in order to accomplish something.Our inspirational guest, Hannah Elizabeth, has been in a wheelchair since she was two years old. She was born with Osteogenesis imperfecta, a genetic disorder that affects her bones and causes them to break easily. Despite the challenges Hannah faces everyday, she always strives to look on the positive side and focus on her abilities rather than what she is unable to do. Hannah was able to discover her passion for beauty and started her own successful makeup youtube channel. Listen in to hear how Hannah uses her talents and optimism to create a legacy and accomplish her dreams.Our final caller, Eric, wants to know how he can stay positive during the pandemic, without worrying so much about the future. Nancy recommends that Eric embrace the moment and utilize this time to spend with his family. Nancy also reminds Eric to be grateful for the gifts he has at this present time and not to dwell on the “what ifs.” Tune in to hear how you can live for today and worry less. Maybe you strive to be honest and empathetic to everyone you meet. Perhaps you want to become an expertise in a cause you are passionate about. Remember that building a legacy doesn't have to be alone. You can have a support group or team to help you achieve your goals. By creating a legacy that allows you to better serve others, as well as improving yourself, is essential to living full out!

My friend and former coworker Nicole EvaNS joins the pod to talk about navigating Osteogenesis imperfecta, pursuing her goals in acting/life in general, and how to empower disabled employees, whether it's on screen or in the office. Nicole is currently on the VERY FUNNY Superstore on NBC and was previously featured on Freeform's Good Trouble. Support GOOD NATURE by donating to their Tip Jar: https://tips.pinecast.com/jar/good-nature This podcast is powered by Pinecast.

"Es liegt extrem viel im Argen, was die Situation behinderter Menschen in Deutschland angeht!" Raul Krauthausen ist zu Gast im Podcast von MundWerk-Training. Was ist eigentlich Aktivismus und warum sind Sozialunternehmer*innen kritisch zu betrachten und gleichzeitig Schnellboote in der Entwicklung zur Inklusion? Wer ist eigentlich verantwortlich und was können wir alle tun, damit Inklusion gelebte Realtität wird? Raul Krauthausen ist u.a. Aktivist für Inklusion und Innovation. Er lebt in Berlin und setzt sich für soziale Projekte ein. Raul Krauthausen hat Osteogenesis imperfecta, Glasknochen und ist auf einen Rollstuhl angewiesen. Er gründete den Verein Sozialhelden und bekam 2013 das Bundesverdienstkreuz verliehen. 2017 war Raul Krauthausen Mitglied der Bundesversammlung. Tragt Euch auch für den wirklich informativen Newsletter ein unter https://raul.de/newsletter

Here’s an opportunity for occupational therapy discussion. After viewing this video, what are your ideas regarding occupational therapy intervention? Does this person need occupational intervention? Hmmm...… Let’s see. Bladen Pietro, otherwise known as Bastrin, from North Carolina, was born with Osteogenesis imperfecta (OI), a genetic disorder that prevents the body from building strong bones, also called brittle bone disease. 

THE ORIGINS OF THE MAJOR ORGANS-There are two major modes of bone formation or osteogenesis, and both involve the transformation of a preexisting mesenchymal tissue into bone tissue. The direct conversion of mesenchymal tissue into bone is called intramembranous ossification. This process occurs primarily in the bones of the skull. In other cases, the mesenchymal cells differentiate into cartilage, and this cartilage is later replaced by bone. The process by which a cartilage intermediate is formed and replaced by bone cells is called endochondral ossification.

Für Außenstehende können seltene Krankheiten faszinierend sein, für Betroffene führen sie jedoch häufig zu lebenslangen Einschränkungen. In einer neuen Folge VITATALK gibt René Glier im Gespräch mit Antje Radünz einen spannenden Einblick in das Leben mit seiner Osteogenesis imperfecta - der Glasknochenkrankheit. Als Experte stand Priv.-Doz. Dr. J. Oliver Semler von der Klinik für Kinder- und Jugendmedizin in Köln beratend zur Seite.

“I want to change a no into a yes. Because yes girls can code. Yes, girls can do whatever they want,” says 12-year-old wunderkind Anna Miller. A coder, app developer, educator, and accessibility activist, Anna Miller is the definition of modern Renaissance Woman.  The fact that she’s a person with Osteogenesis imperfecta feels like a minor detail when she shares the passion that powers her forward. Find out how she’s building a more accessible world and creating an app that could change the lives of millions.For more information about Microsoft's In Culture podcast, please visit: microsoft.com/inculture/podcast

Simon Dharmakirthi is a special guy in many ways. He loves the Orlando Magic more than anyone I know and his heart is always in the right place. He was born with the rarest bone disease in the world (Osteogenesis imperfecta) but he doesn't let that get him down. I wanted to chat with him to share his amazing story of survival and joy. He shares some amazing advice that ANYONE can learn from. He inspires me with his incredible attitude and some of the knowledge he gives for when you are down will surely lift you up and get you going in the right direction.

https://pbs.twimg.com/profile_images/241340701/muls_400x400.jpg More from Taniya Taniya on Twitter (https://twitter.com/taniyafaulk) Taniya on Instagram (https://www.instagram.com/kreativekayos/?hl=en) Taniya's Website (http://www.taniyafaulk.com) More from Ability Jacob on Twitter (http://twitter.com/TheJacobHolt) Ability on Twitter (http://twitter.com/abilitypodcast) Ability on Facebook (https://www.facebook.com/AbilityPodcast/) Referenced Osteogenesis Imperfecta (https://en.wikipedia.org/wiki/Osteogenesis_imperfecta)

https://pbs.twimg.com/profile_images/901223773331783680/nzPevsOE_400x400.jpg In this episode Jacob remembers the life of Quentin Kenihan. More from Quentin Link to Original Epiosode (https://abilitypodcast.com/qkenihan) Quentin on Twitter (https://twitter.com/qkenihan?lang=en) Quentin on Youtube (https://www.youtube.com/user/qkenihan) Quentin's Podcast The Qcast (https://podcasts.apple.com/us/podcast/the-q-cast-with-quentin-kenihan/id1387094756?mt=2) Not All Superheros Wear Capes (By Quentin Kenihan) (https://www.goodreads.com/book/show/32195052-not-all-superheroes-wear-capes) More from Ability Jacob on Twitter (http://twitter.com/TheJacobHolt) Ability on Twitter (http://twitter.com/abilitypodcast) Ability on Facebook (https://www.facebook.com/AbilityPodcast/) Referenced Osteogenesis Imperfecta (https://en.wikipedia.org/wiki/Osteogenesis_imperfecta) Quentin Archival Footage (YouTube) (https://www.youtube.com/watch?v=2ODUfYjN_WU) Quentin on Saturday Night (YouTube) (https://www.youtube.com/watch?v=Xl8EQcHZWT0) Mike and Quentin Reunited (YouTube (https://www.youtube.com/watch?v=negCEgOKc7Y) Quentin Wikipedia (https://en.wikipedia.org/wiki/Quentin_Kenihan)

Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions:  Bria: I am desperate for help for my sister. Please!! For two years, she’s been unable to eat almost anything except a few foods. One mistaken ingredient, and she’s vomiting for 72 hours with a raging migraine. Even a sip of water causes her to vomit so she can’t keep anything down during this period of time, not medicine, not electrolytes, nothing. She knows she has Cibo, and bought the CBO protocol from your site. One pill sent her over the edge and into severe vomiting for three days. Please help! Western medicine doctors call it acid reflux but we know it’s not tha. How can she get the Cibo out of her system if she can’t even take one pill? The number of days of missed work, the amount of money spent, and the helplessness of her husband and her family is very difficult to watch. She recently saw a functional medicine practitioner in Anaheim California, but hasn’t been able to even start that lingual medicine yet. We need guidance. Thank you. Bria Jeanette: (I felt I couldn’t ask this question on the Facebook page due to privacy for my daughter) I have searched the list of podcast topics and have not located any information on osteogenesis imperfector. My daughter was clinically diagnosed with OI type 1 twenty years ago and has had ten fractures predominantly involving leg bones. Prior to 2011 she had not endure pain other than when she broke. In March 2011 she had to move 4 hours away to attend university and that very weekend she had to be hospitalised for an absus removal. Soon after she started having back pain and has endured 8 years of constant pain while studying a pharmacy degree. Over this time Ok she has taken anti inflammatories of varying strengths since it started in 2011. Plus a paracetamol every day at a full dose. She was on tramadol from May 2011 - October 2018 and now Is taking palexia. She took omeprazole along side the anti inflammatory as well. It seems as a result of the medication she has an ulcer and has regular bouts of diarrhoea. She lost 10kg in 2018 and was hoping with this she would lessen the pain which has only happened a little. When she tries to exercise the pain gets worse. As a mum I hate to see her in pain. In 2012 we took her to an alternative practitioner who had her on water and fruit for six months, but it made no difference and consequently she is very sceptical of all things alternative. As an wellness client I am starting to experience success Please help me with some ideas for my daughter. Kira: Do you have a list of recommended function medicine practitioners in certain areas or do you have a suggestion for finding a good one. I live in Fair Oaks, CA. Thanks. Patrick: Thanks so much for sharing all of your knowledge I can’t even express you how much I appreciate it. Im 45 years young 5/7 and weigh 170 when I started listening to you 6 months ago I was 205 . just making some simple life changes and taking your Daily Nutritional Support shake. I’ve always been very active but now feel the best I ever felt . I’ve been listening to about 3 or 4 of your podcasts a day. since hearing the ones on saunas I now try to use one 3 days a week for 20 minutes I know you say it’s a great way to detox and has a ton of benefits but I’m not sure if you answered if it detoxs heavy metals , if I can’t get to the gym to use the sauna I take a dr teals epson salt bath will that have some of the same benefits and will that detox heavy metals. Thanks again for all you do and keep up the good work . Elizabeth: Hey Dr Cabral, recently I came across Serrapeptase and found it very interesting, particularly concerning circulation and cysts. I decided to take 80,000IU Serra for a cyst located on the inframammary fold of the breast as it appears Serra may be extremely helpful for eliminating cysts. Unfortunately, upon using Serra on two separate occasions, it caused vomiting (the second time I took only one tablet). I contacted the company to ask if this could possibly be a detox/herxheimer reaction or if generally it does not agree with the body, unfortunately they were unhelpful. Having done some further research, Serra can result in nausea and may be best to start off with a lower potency, even though the majority of Serra start at 40,000iu. I did a podcast search and you briefly mention Serrapeptase on podcast 617, the notes link is missing so not sure of the brand suggested but wondered if you had any thoughts? Perhaps it can conflict with some people and I should just discontinue? (May also have underlining candida/thyroid issues). Thank you always for all you do. Elizabeth: Hi Dr Cabral, could you suggest anything for getting bloated on a flight? I tend to not eat/drink anything during a flight (unless I'm flying business it may be a light meal and bottled mineral water). I tend to have peppermint tea (at least two cups) before the flight. Even on a sleeper service flat bed and not eating or drinking anything may cause some bloating. I never touch the water/tea/coffee on a flight due to the hygiene. Even after a flight I can occasionally be left bloated for a couple of days. Does an aggravated/inflamed stomach during a flight specifically indicate something such as candida or is it simply the air pressure can be hard on a sensitive stomach? Is there anything you would recommend that would prevent an uncomfortable stomach during a flight? Thank you very much.   Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community’s questions!  - - - Show Notes & Resources: http://StephenCabral.com/1135 - - - Get Your Question Answered: http://StephenCabral.com/askcabral   - - - Dr. Cabral's New Book, The Rain Barrel Effect https://amzn.to/2H0W7Ge - - - Join the Community & Get Your Questions Answered: http://CabralSupportGroup.com - - -   Dr. Cabral’s Most Popular Supplements: > “The Dr. Cabral Daily Protocol” (This is what Dr. Cabral does every day!) - - - > Dr. Cabral Detox  (The fastest way to get well, lose weight, and feel great!) - - - > Daily Nutritional Support Shake  (#1 “All-in-One recommendation in my practice) - - - > Daily Fruit & Vegetables Blend  (22 organic fruit & vegetables “greens powder”) - - - > CBD Oil  (Full-spectrum, 3rd part-tested & organically grown) - - - > Candida/Bacterial Overgrowth, Leaky Gut, Parasite & Speciality Supplement Packages - - - > See All Supplements: https://equilibriumnutrition.com/collections/supplements  - - -   Dr. Cabral’s Most Popular At-Home Lab Tests: > Hair Tissue Mineral Analysis (Test for mineral imbalances & heavy metal toxicity) - - - > Organic Acids Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Thyroid + Adrenal + Hormone Test  (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Adrenal + Hormone Test (Run your adrenal & hormone levels) - - - > Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Omega-3 Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - > Stool Test (Use this test to uncover any bacterial, h. Pylori, or parasite overgrowth) - - - > Genetic Test (Use the #1 lab test to unlocking your DNA and what it means in terms of wellness, weight loss & anti-aging) - - - > Dr. Cabral’s “Big 5” Lab Tests (This package includes the 5 labs Dr. Cabral recommends all people run in his private practice) - - - > View all Functional Medicine lab tests (View all Functional Medicine lab tests you can do right at home for you and your family!)

In this episode of the Award-winning PRS Journal Club Podcast, 2018 Resident Ambassadors to the PRS Editorial Board – Francesco Egro, Nicole Phillips, and Ira Savetsky - and special guest Justine C. Lee, MD, PhD, discuss the following articles from the December 2018 issue:  “Can Functional Nasal Surgery Treat Chronic Headaches? A Systematic Review” by Farmer, Garg, and Afifi. “Evolving Trends in Textured Implant Use for Cosmetic Augmentation in the United States” by Tandon, DeLong, Ballard, et al. “Distraction Osteogenesis for Unicoronal Craniosynostosis: Rotational Flap Technique and Case Series” by Brandel, Dalle Ore, Reid, et al. Special Guest Justine C. Lee, MD, PhD, Bernard G. Sarnat Endowed Chair for Craniofacial Biology, and Associate Professor at the UCLA Division of Plastic and Reconstructive Surgery. #PRSJournalClub

https://uploads.fireside.fm/images/0/0bd910df-1d4c-44d9-9335-d60dc1b9e7ad/Rv5aM6ke.png In this episode Jacob talks to Samantha Renke. Samantha is an Actress and Television Presenter in the UK. More from Samantha Renke Samantha on Twitter (https://twitter.com/samrenke?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor) Samantha on Instagram (https://www.instagram.com/samantharenke/?hl=en) Samantha on Loose Women (https://www.youtube.com/watch?v=7Ta-enfHlBg&t=82s) Samantha's Writing in Huffpost UK (https://www.huffingtonpost.co.uk/author/samantha-renke/) More from Ability Jacob on Twitter (http://twitter.com/TheJacobHolt) Ability on Twitter (http://twitter.com/abilitypodcast) Ability on Facebook (https://www.facebook.com/AbilityPodcast/) Referenced Osteogenesis Imperfecta (https://en.wikipedia.org/wiki/Osteogenesis_imperfecta) Shewee (https://www.shewee.com)

In this episode of Tales from the PROS, I chat with the amazing Sean Stephenson, who has inspired millions of people around the globe through his YouTube videos, books, and famous Ted Talks. He is a global leader, influencer, one of the most well known motivational speakers, and self-help authors today.  Me and Sean talk about how to find your passion, what creates and maintains happiness, and living a purpose-driven life. We also chat about personal branding, how to engage with an audience, and much more.  Questions Asked: Sean, I have been following you for years now and your content and messages are incredibly inspiring to say the least. I want to kick things off by asking you what does it mean to live a purpose-driven life. How did you find your purpose?  Did you ever think you would where you are today helping millions around the world? What inspired you the most to share your story? We all keep talking about being happy, but in your thoughts, what does that really mean? I am sure you get this a lot, everyone thinks that your always happy and living this amazing life, but what are some of your biggest fears and do you think fear can play a positive in our lives? To get to this point of success in life is about overcoming adversity and living and fulfilling your purpose, so what have been some of your biggest challenges other than anything physical? Do you feel that living a purpose-driven life and being happy are connected, or do you think they serve different purposes? I know that you are a world-renowned speaker, in your experience what does it take to engage with the audience on an emotional level, so you can change their lives? Do you ever get nervous before a talk? In your experience being an entrepreneur, what approach or business strategy did you follow in order to create such a strong personal brand? I always ask the THREE HOW'S: How do you define failure? How do you define entrepreneurship? How do you define success?   Follow Sean Stephenson: Website - https://seanstephenson.com/  Facebook - https://www.facebook.com/theseanstephenson/  Twitter - https://twitter.com/TheSeantourage   YouTube: https://www.youtube.com/user/Seanclinch  Instagram: https://www.instagram.com/3footgiant/ Follow Me: Podcast Website - https://www.talesfromthepros.com  Company Website - https://www.imaginovation.net  Facebook - https://www.facebook.com/TalesfromthePROS/  Twitter - https://twitter.com/MGeorgiou22   Instagram - https://www.instagram.com/the_mgeorgiou/  YouTube: https://www.youtube.com/channel/UCJv9pbImovknEluSLzAPTpg/featured 

More from Quentin Quentin on Twitter (https://twitter.com/qkenihan?ref_src=twsrc%5Eappleosx%7Ctwcamp%5Esafari%7Ctwgr%5Eprofile) Quentin on Youtube (https://www.youtube.com/channel/UCO0w7WeJinZupD_Q1Zw0FRw) Quentin on Instagram (https://www.instagram.com/qkenihan/?hl=en) Quentin's Website (http://quentinkenihan.com.au) The Q Cast (https://itunes.apple.com/us/podcast/interview-with-penne-dennison/id1387094756?mt=2) More from Ability Jacob on Twitter (http://twitter.com/TheJacobHolt) Ability on Twitter (http://twitter.com/abilitypodcast) Ability on Facebook (https://www.facebook.com/AbilityPodcast/) Referenced Osteogenesis Imperfecta (https://en.wikipedia.org/wiki/Osteogenesis_imperfecta) Mad Max Fury Road (https://en.wikipedia.org/wiki/Mad_Max:_Fury_Road) National Disability Insurance Scheme (https://en.wikipedia.org/wiki/National_Disability_Insurance_Scheme) Bisphosphonates (Class of Drug) (https://en.wikipedia.org/wiki/Bisphosphonate)

In this episode Jacob talks to Tarah Schaeffer. Tarah is a former Sesame Street actress and currently studying to be a psychologist. More from Tarah Tarah on Twitter (https://twitter.com/tarahlschaeffer?lang=en) Tarah's Muppet Wiki Page (http://muppet.wikia.com/wiki/Tarah_Schaeffer) More from Ability Ability on Twitter (http://twitter.com/abilitypodcast) Jacob on Twitter (http://twitter.com/TheJacobHolt) Ability on Facebook (https://www.facebook.com/AbilityPodcast/) Referenced Osteogenesis Imperfecta (https://en.wikipedia.org/wiki/Osteogenesis_imperfecta) Sesame Street (https://en.wikipedia.org/wiki/Sesame_Street) The Go Round (Tarah's song from Sesame Street) (https://www.youtube.com/watch?v=zO2MsEEk5q4&t=29s)

Osteogenesis imperfecta (OI) is a rare disorder that causes bones to break easily. Children with OI may sustain broken bones from seemingly minor injuries where children without the disorder may not have a fracture. The motion analysis center located inside Shriners Hospitals for Children, provides motion analysis to children and uses the data collected to help doctors provide the most effective care for each patient, including those with osteogenesis imperfecta (OI).In this inspiring segment, learn about gait analysis for children, OI and the exciting new research being done at Shriners Hospital for Children with the guest, Peter Smith, MD. He is an attending orthopaedic surgeon and director of the OI clinic at Shriners Hospitals for Children. Additionally, Dr. Smith is the medical director of the hospital’s motion analysis center.

In this episode I talk to Angie Wallace-Skaggs. Angie has Osteogenesis Imperfecta. Read about Osteogenesis Imperfecta Read about Shriners Hospital for Children Follow Ability on Twitter Follow Jacob on Twitter Osteogenesis Imperfecta Foundation

In this episode I talk to Author Tony Jacobsen. Read about Osteogenesis Imperfecta Get Tony's Book Follow Ability on Twitter Follow Tony on Twitter Follow Jacob on Twitter

In this episode we talk to Podcaster Jacob Holt. Read about Osteogenesis Imperfecta Special Thanks to Destiny Dyer for Hosting this episode. Follow Ability on Twitter Follow Destiny on Twitter Follow Jacob on Twitter Special Guest: Destiny Dyer.

This episode I speak with Jane Hash who also has Osteogenesis Imperfecta. It's a really fun episode I hope you enjoy it. Learn about Osteogenesis Imperfecta Classy Little Fashions Follow Jane on Twitter Follow Ability on Twitter Follow Jacob on Twitter Special Guest: Jane Hash.

In this episode I talk to Destiny Dyer who has Osteogenesis Imperfecta Type III. Learn about Osteogenesis Imperfecta Follow Destiny on Twitter Follow Ability on Twitter Follow Jacob on Twitter Special Guest: Destiny Dyer.

What excuses are you making that keep you from living your best life? Sean Stephenson is here to tell you today that they're hogwash! Standing at 3 feet tall with his wheelchair to move him through life, Sean knows every obstacle and every excuse that keep people from their dreams. In this episode, he reveals the very simple (stupidly simple) practices he uses each day as the foundation to live his dreams. In this episode, you will learn: -The importance of connecting to role models, surrounding yourself with positive people, and ditching the people who hold you down. -What's in Camille's superfood smoothie (you can get the goods here: http://bit.ly/RNHBqn) -Sean's secrets for massive energy. -How to craft a "when life works" list (and why its totally essential you do). -That all of personal growth boils down to 6 simple words. Can you guess them? -How to become a master of your own life. -Why YOU are the best investment around. -Sean's mission to rid the world of insecurity. -The difference between a mature and an immature person. About Sean (in his words): "When I was born doctors predicted I would not to survive past birth because of a rare bone disorder that stunted my growth and caused my bones to be extremely fragile. Despite these challenges, I’ve taken a stand for a quality of life that has reached millions of people around the world, including Sir Richard Branson, President Clinton, and his Holiness the 14th Dalai Lama. I’ve appeared on everything from The Oprah Show to Youtube videos with millions of views. The Biography Channel did an hour feature on my life called, “Three Foot Giant.” My message has been heard at live events in over 15 countries and 47 states over the past 16 years. My latest book, “Get Off Your But” has swept the US and been released in over a half dozen languages around the world. As a board certified therapist, I use humor and compassion to develop a fun environment where individuals open their hearts and minds for lasting empowerment to occur." Connect with Sean at www.seanstephenson.com Want to learn exactly how Sean makes $10,000 for 1 talk? He's hosting an amazing free webinar to teach you exactly how! REGISTRATION LINK: http://SeanStephensonSpeakingSecrets.com DATE/TIME: Tuesday June 3rd, 2014 at 5pm PT/8pm ET --- Rate, review and subscribe to Paleo, Love & Transformation: http://bit.ly/1ocRlVu Get 7 Days to Unlock Your Inner Beauty: www.schoolofinnerbeauty.com Get started eating paleo with the Paleogasm Starters Guide: www.paleowithcamille.com

Three awesome guests join me on this episode of Hash It Out With Jane, to help celebrate what O.I. Awareness Day means to them and their families.

Fredrick Brennan was recently featured in the New York Times after being the victim of a mugging in NYC. This certainly isn't a rare occasion in the big apple but Brennan's story is different from the norm. Aside of the fact that he is a small statured wheelchair user, his reason for traveling with a significant wad of cash will open your eyes to a shocking reality facing many people with disabilities.

Katherine Klimitas is a painter, jewelry designer, graphic artist and author of a book called, "Looking Up." In this book she colorfully illustrates her perspective on life from her wheelchair.

Biography Channel's "3 Foot Giant" Oprah, CNN ~ Sean Stephens is an awesome example of a game changer. He recently became a newlywed, Congratulations Sean & Mindie! He is also a is a board-certified psychotherapist, and his a great book called, "Get off Your 'BUT': How to end self-sabotage and stand up for yourself." Expected to die at birth, Sean Stephenson has faced an army of reasons to give up and countless opportunities to embrace pity. He suffered more than 200 bone fractures by age eighteen, reached a height of only three feet, and is permanently confined to a wheelchair. Despite his challenges, he took a stand for a quality of life that has inspired millions of people around the world, including Tony Robbins, Richard Branson, and President Clinton. Sean has had more life adventures than most people who are twice his age. He worked on Capitol Hill for a U.S. Congressman and in the White House alongside President Clinton. He has also testified in front of the United States Senate on two separate occasions, traveled the world as a professional speaker in 11 countries and 47 states, He has appeared in dozens of national media outlets including: Oprah, CNN, The Discovery Health Channel, WGN, and CBS News, and in The New York Times. Sean also starred on The Biography Channel with his story called " 3 Foot Giant" Join Me on Facebook @ https://www.facebook.com/BuildingAbundantSuccess

This episode is better than beans on toast! Sam Renke, an up and coming British Actress with a disability and Director Max Barber were so much fun to chat with that I ended up breaking down the interview into two episodes! I just couldn't bare to cut any of our silly yet informative dialogue.

Background: Mutations in the FKBP10 gene were first described in patients with Osteogenesis imperfecta type III. Two follow up reports found FKBP10 mutations to be associated with Bruck syndrome type 1, a rare disorder characterized by congenital contractures and bone fragility. This raised the question if the patients in the first report indeed had isolated Osteogenesis imperfecta or if Bruck syndrome would have been the better diagnosis. Methods: The patients described here are affected by severe autosomal recessive Osteogenesis imperfecta without contractures. Results: Homozygosity mapping identified FKBP10 as a candidate gene, and sequencing revealed a base pair exchange that causes a C-terminal premature stop codon in this gene. Conclusions: Our study demonstrates that FKBP10 mutations not only cause Bruck syndrome or Osteogenesis imperfecta type III but can result in a severe type of isolated Osteogenesis imperfecta type IV with prenatal onset. Furthermore, it adds dentinogenesis imperfecta to the spectrum of clinical symptoms associated with FKBP10 mutations.