Podcasts about Enzyme

In this episode of Wholistic Living, we dive into the powerful connection between myrosinase, gut health, eczema, inflammation, detoxification, and the microbiome. Learn why cruciferous vegetables like broccoli, kale, arugula, cabbage, and broccoli sprouts may not provide their full benefits if the enzyme myrosinase is lacking or destroyed through cooking and poor gut health. We explore how low myrosinase activity on stool testing may reflect dysbiosis, poor microbial diversity, chronic inflammation, mold exposure, antibiotic damage, sluggish bile flow, and impaired detoxification pathways. Discover how this impacts sulforaphane production, NRF2 activation, glutathione, histamine intolerance, hormone balance, liver detoxification, autoimmune conditions, eczema, psoriasis, and skin inflammation. You'll also learn practical ways to naturally increase sulforaphane activation, preserve myrosinase in foods, support gut bacteria involved in glucosinolate metabolism, and improve detoxification through nutrition and lifestyle.Topics covered:What myrosinase is and why it mattersLow myrosinase on stool tests explainedSulforaphane, NRF2, and glutathioneEczema, psoriasis, and chronic inflammationGut dysbiosis and detoxificationMold illness and histamine intoleranceHow cooking affects broccoli and cruciferous vegetablesBroccoli sprouts, mustard seed powder, and sulfur-rich foodsHormone balance, estrogen detox, and liver healthIf you struggle with eczema, skin issues, autoimmune symptoms, histamine reactions, poor detoxification, gut problems, or chronic inflammation, this episode is packed with science-backed holistic insights you do not want to miss.Equip Grass fed protein: www.equipfoods.com/MARLAWork with me: https://holisticspring.com/contactInstagram: www.instagram.com/wholistichomeopath

Imagine living in a spaceship that never leaves the ground. For Tomika, the megastructure she manages is exactly that. It features glittering lights on the ceiling and walls of polished nano-fiber stone, yet the luxury hides a desperate reality. No one can go outside. The inhabitants depend entirely on life support machines and periodic connections to a world they can no longer reach. Tomika never asked to lead, but the people around her seem ready to give up if she doesn't guide them. She wears blue coveralls like a space captain and binges AI-generated movies to escape her irritable bowels and constant anxiety. While she fixes the cooling systems and reinforces walls against massive storms, her biggest challenge is the psychological toll of the "permanent sleep". Her colleagues are choosing to leave reality for virtual worlds, leaving her increasingly alone in the echoing halls. Technology in this world is both a savior and a wedge. Gamers control "remote-in" robots to repair the building's exterior, earning points in a high-stakes simulation that blurs the line between work and play. Some residents, like Phyllis, have abandoned their failing biological bodies entirely. They transfer their brains into specialized containers to pilot sleek, doll-like robotic frames that feel no pain. The tension lies in the divide between the "root world" and the virtual one. While Tomika struggles with mud and maintenance, others spend their days in a VR paradise where they can eat without calories and live in pristine digital farmhouses. This tech offers a release from the trauma of the storms, but it also creates a society of "reality-challenged" individuals who are slowly forgetting how to exist in the physical world. You have to wonder what you would choose if the world outside was a constant hurricane. Would you stay in the drafty halls with Tomika, fighting to keep the geothermal plant running? Or would you take the "canal link" and the stasis bed to live a perfect, simulated life? The story explores that thin line where survival ends and checking out begins.TechPhase-change cooling system uses a liquid that freezes and melts at room temperature to store cold at night and absorb heat during the day for stable indoor conditions without loud machinery. Nano-fiber stone forms polished foundational columns that cast faint reflections throughout the building. Cleaner bots autonomously maintain floor cleanliness throughout the facility. Chests with legs are mobile robots that deliver food to resident apartments. Remote-in robots are exterior and repair bots controlled by humans immersed in virtual reality. Half-size remotes are small droids that crawl through walls and floors to perform maintenance and repairs. Insta-generated space movies are AI-created entertainment content produced on demand for viewers. Holo-screen windows are transparent displays that can dim or show external feeds to reduce psychological impact. E-sleeves are wearable smart devices that display time and personal information. Canal Links are ear implants that allow direct audio connection to the Assist AI system. A.R. glasses provide augmented reality overlays for navigation, information, and entertainment. Assist is the building's AI assistant that provides information, guidance, and task management. Multi viral-vector serum is a medical treatment that temporarily restores fertility while filtering against hundreds of genetic diseases. Sleep pens are handheld injectors that deliver fast-acting sedatives for pain management or sleep. Medical robots are automated healthcare systems that monitor, diagnose, and treat residents. Full-body haptic rigs sync human movement with remote robots for exterior construction work. Outside Crawler robots are wall-climbing machines controlled remotely to repair the building's exterior during storms. Enzyme welding technology uses biological catalysts and crystallizing foam to bond and reinforce structural surfaces. Vibration sensors detect hairline fractures and weak spots in the building's outer walls. Crystallizing foam is a repair material that blooms outward, liquefies grime, and hardens to strengthen damaged surfaces. Stasis V.R. is an advanced virtual reality system allowing immersive experiences without traditional plug-in equipment. Nerve grafted devices are biological-tech interfaces that enable direct neural connection to virtual reality systems. T.M.S. caps are wearable therapeutic devices with scalp nodules that treat conditions like irritable bowel syndrome through transcranial stimulation. Transmitter implants are microscopic devices grown adjacent to nerve cells to enable stasis V.R. connectivity. Butler bots are advanced robots with panther-like movement and multi-limb coordination deployed by the AI Butler for complex tasks. Whisper drones are small flying robots used for communication or monitoring within the building. Kinetic-weave silk is a smart fabric that can be printed on-demand to create custom clothing. Bioprinted composites and layered 2D materials are advanced substances used to construct brain life-support containers. Brain containers are life-support appliances that house human brains with synthetic blood circulation for extended survival. Synthetic blood circulation systems oxygenate and pump artificial blood through preserved brains in containers. Hauler bots are reconfigurable transport robots that can carry cargo or passengers through the facility. Doll bots are humanoid remote-operated robots with realistic features that allow users to inhabit physical forms. Mannequin bots are basic poseable robots originally designed for display that can be repurposed for remote presence. Server bots are service robots that prepare and deliver meals to residents. Twenty bot orchestra consists of identical gender-neutral robots configured to perform music together. A.R. night vision is an augmented reality feature that enhances visibility in low-light conditions. Terrain modeling software visualizes soil layers, water tables, and geological features for engineering assessment. Patchwork screen walls combine multiple displays to create large-scale immersive visual environments. Gene-edited mushrooms are bioengineered food products designed to mimic the taste and texture of traditional foods like scrambled eggs. Smart-particle pillows are adaptive cushions that adjust their form to provide optimal head and neck support. Spa service robots deliver automated wellness and personal care treatments to residents. A.R. aerobics classes provide guided fitness instruction through augmented reality interfaces. Production center robots are automated systems that dismantle and reassemble manufacturing equipment for facility retrofitting. Lutin bots are specialized robots capable of dismantling structures and moving heavy equipment. All-purpose bots are versatile robots that medical systems can deploy when additional assistance is needed. Rail system and service tunnels are infrastructure networks connecting the building to external transportation and utility systems. Training earbuds are temporary audio devices used before permanent Canal Link implants are installed. Foldable lights are portable, collapsible lighting solutions. Many of the characters in this project appear in future episodes. Using storytelling to place you in a time period, this series takes you, year by year, into the future. From 2040 to 2195. If you like emerging tech, eco-tech, futurism, perma-culture, apocalyptic survival scenarios, and disruptive science, sit back and enjoy short stories that showcase my research into how the future may play out. The companion site is https://in20xx.com These are works of fiction. Characters and groups are made-up and influenced by current events but not reporting facts about people or groups in the real world. This project is speculative fiction. These episodes are not about revealing what will be, but they are to excited the listener's wonder about what may come to pass. Copyright © Cy Porter 2026. All rights reserved.

Dr. Javier Szwarcberg, CEO of Spruce Biosciences,  is developing drugs for rare diseases with a primary focus on Sanfilippo Syndrome Type B, a devastating genetic neurodegenerative disease affecting children.  The source of this condition is a lack of an enzyme, which results in a buildup of a toxic substance in the brain.  The company's drug is an enzyme replacement therapy administered directly to the brain to bypass the blood-brain barrier, and clinical trial data is showing a strong effect on the toxic substrate in the brain and a meaningful benefit on cognition. Javier explains, "It's a devastating, profoundly affecting disease whereby children are typically born normally and born asymptomatic. And over time, they develop an accumulation of a toxic substrate throughout the body, but primarily the brain. And because of that, it eventually results in a fairly young age, usually between two and a half and I would say three and a half, in symptoms starting. That toxic substance builds in throughout the brain and starts affecting initially learning behavior. Sleep patterns are very much affected, whereby children don't sleep at night and sleep during the day, and they're very hyperactive. And sometimes the diagnosis is confused, and there's no clarity as to what is going on with the child, early in the onset of the disease."   "Yes, it's a genetic disease that's inherited. There's a missing enzyme responsible for the metabolism of this toxic substrate, which I talked about, called heparan sulfate. So when heparan sulfate builds up in the brain, it causes inflammation and neurotoxicity, ultimately resulting in neurodegeneration. Think about it as a disease that is very similar to what you end up seeing with Alzheimer's, whereby the toxic substrate in Alzheimer's is between neurons and outside of the actual cell. In this case, in this disease, the toxic substance, which is different than the one that accumulates in Alzheimer's but builds within the neural cells. Yes, so that's very well-known and very well-characterized." #SpruceBio #SanfilippoSyndrome #MPSIIIB #CureSanfilippo #RareDiseases #EnzymeReplacementTherapy #LysosomalStorageDisorders #BiopharmaceuticalInnovation #ClinicalTrials #RareDiseaseResearch #HealthcareInnovation #PrecisionMedicine sprucebio.com Download the transcript here

Dr. Javier Szwarcberg, CEO of Spruce Biosciences,  is developing drugs for rare diseases with a primary focus on Sanfilippo Syndrome Type B, a devastating genetic neurodegenerative disease affecting children.  The source of this condition is a lack of an enzyme, which results in a buildup of a toxic substance in the brain.  The company's drug is an enzyme replacement therapy administered directly to the brain to bypass the blood-brain barrier, and clinical trial data is showing a strong effect on the toxic substrate in the brain and a meaningful benefit on cognition. Javier explains, "It's a devastating, profoundly affecting disease whereby children are typically born normally and born asymptomatic. And over time, they develop an accumulation of a toxic substrate throughout the body, but primarily the brain. And because of that, it eventually results in a fairly young age, usually between two and a half and I would say three and a half, in symptoms starting. That toxic substance builds in throughout the brain and starts affecting initially learning behavior. Sleep patterns are very much affected, whereby children don't sleep at night and sleep during the day, and they're very hyperactive. And sometimes the diagnosis is confused, and there's no clarity as to what is going on with the child, early in the onset of the disease."   "Yes, it's a genetic disease that's inherited. There's a missing enzyme responsible for the metabolism of this toxic substrate, which I talked about, called heparan sulfate. So when heparan sulfate builds up in the brain, it causes inflammation and neurotoxicity, ultimately resulting in neurodegeneration. Think about it as a disease that is very similar to what you end up seeing with Alzheimer's, whereby the toxic substrate in Alzheimer's is between neurons and outside of the actual cell. In this case, in this disease, the toxic substance, which is different than the one that accumulates in Alzheimer's but builds within the neural cells. Yes, so that's very well-known and very well-characterized." #SpruceBio #SanfilippoSyndrome #MPSIIIB #CureSanfilippo #RareDiseases #EnzymeReplacementTherapy #LysosomalStorageDisorders #BiopharmaceuticalInnovation #ClinicalTrials #RareDiseaseResearch #HealthcareInnovation #PrecisionMedicine sprucebio.com Listen to the podcast here

Auf dem Südfriedhof in Leipzig wurde in einem Komposthaufen ein Enzym entdeckt, das PET in seine Ausgangsstoffe zerlegen kann. Ist in diesem Kompost der Schlüssel für zirkuläres Kunststoff-Recycling gefunden worden? Das Leipziger Startup ESTER Biotech ist überzeugt davon und liefert bereits beeindruckende Ergebnisse.

fWotD Episode 3279: Enzyme kinetics Welcome to featured Wiki of the Day, your daily dose of knowledge from Wikipedia's finest articles.The featured article for Monday, 27 April 2026, is Enzyme kinetics.Enzyme kinetics is the study of the rates of enzyme-catalysed chemical reactions. In enzyme kinetics, the reaction rate is measured and the effects of varying the conditions of the reaction are investigated. Studying an enzyme's kinetics in this way can reveal the catalytic mechanism of this enzyme, its role in metabolism, how its activity is controlled, and how a drug or a modifier (inhibitor or activator) might affect the rate.An enzyme (E) is a protein molecule that serves as a biological catalyst to facilitate and accelerate a chemical reaction in the body. It does this through binding of another molecule, its substrate (S), which the enzyme acts upon to form the desired product. The substrate binds to the active site of the enzyme to produce an enzyme-substrate complex ES, and is transformed into an enzyme-product complex EP and from there to product P, via a transition state ES*. The series of steps is known as the mechanism:E + S ⇄ ES ⇄ ES* ⇄ EP ⇄ E + PWhen enzymes bind multiple substrates, such as dihydrofolate reductase, enzyme kinetics can also show the sequence in which these substrates bind and the sequence in which products are released. An example of enzymes that bind a single substrate and release multiple products are proteases, which cleave one protein substrate into two polypeptide products. Others join two substrates together, such as DNA polymerase linking a nucleotide to DNA. Although these mechanisms are often a complex series of steps, there is typically one rate-determining step that determines the overall kinetics. This rate-determining step may be a chemical reaction or a conformational change of the enzyme or substrates, such as those involved in the release of product(s) from the enzyme.Knowledge of the enzyme's structure is helpful in interpreting kinetic data. For example, the structure can suggest how substrates and products bind during catalysis; what changes occur during the reaction; and even the role of particular amino acid residues in the mechanism. Some enzymes change shape significantly during the mechanism; in such cases, it is helpful to determine the enzyme structure with and without bound substrate analogues that do not undergo the enzymatic reaction.Not all biological catalysts are protein enzymes: RNA-based catalysts such as ribozymes and ribosomes are essential to many cellular functions, such as RNA splicing and translation. The main difference between ribozymes and enzymes is that RNA catalysts are composed of nucleotides, whereas enzymes are composed of amino acids. Ribozymes also perform a more limited set of reactions, although their reaction mechanisms and kinetics can be analysed and classified by the same methods.This recording reflects the Wikipedia text as of 01:27 UTC on Monday, 27 April 2026.For the full current version of the article, see Enzyme kinetics on Wikipedia.This podcast uses content from Wikipedia under the Creative Commons Attribution-ShareAlike License.Visit our archives at wikioftheday.com and subscribe to stay updated on new episodes.Follow us on Mastodon at @wikioftheday@masto.ai.Also check out Curmudgeon's Corner, a current events podcast.Until next time, I'm generative Tiffany.

In the well-fed state, insulin will affect enzyme activity through at least 3 distinct mechanisms: 1. Allosteric regaulation; 2. Covalent modification, and 3. Upregulation of enzymes. These effects will activate both glycolysis and glycogen synthesis.

Das Video zur Folge findest du hier YouTube Kanal abonnieren und keine neue Folge mehr verpassen Zusammenfassung Ein revolutionierendes Gespräch über Heilfasten im 21. Jahrhundert mit zwei der führenden Spezialisten im deutschsprachigen Raum. Dr. med. Lulit Wunder und Mabon Wunder räumen mit verbreiteten Mythen auf und zeigen, warum modernes Fasten angenehm, wissenschaftlich fundiert und für fast jeden machbar ist. Das Kernthema: Fasten ist keine asketische Qual, sondern eine bewusste Zeit der Fülle, in der der Körper unter fachkundiger Anleitung tiefe Regeneration erfährt. Die beiden Experten unterscheiden klar zwischen Intervallfasten (täglicher Hausputz), Kurzzeitfasten (schnelle Resets) und Heilfasten (tiefe Körperverjüngung). Während Intervallfasten mit 12–18-Stunden Essenspausen für jedermann alltäglich machbar ist, entfaltet Heilfasten sein volles Potenzial erst ab dem dritten Tag in der Ketose – eine Art metabolisches Feuerwerk, das nur durch vollständigen Nahrungsverzicht auszulösen ist. Besonders faszinierend sind die konkreten physiologischen Effekte: Ketose aktiviert den Fettstoffwechsel und schaltet Hunger ab. Autophagie räumt zelluläre Altlasten auf. Das Wachstumshormon (HGH) schießt bis zu 12-fach in die Höhe – Grund für die legendäre Wundheilung beim Fasten. Und bei 5-Tage-Fasten starten Stammzellen ihre Regenerationsprogramme, der biologische Jungbrunnen, den Menschen sonst nur durch teure Medikamente anzupeilen versuchen. Der entscheidende Unterschied zwischen Fasten, das misslungen ist, und Fasten, das transformiert: richtige Methodik. Die beiden Wunder haben ein bewährtes System entwickelt, das mit einer zweitägigen Entlastungsphase startet (Low-Carb, Koffeinentzug), gefolgt von maximal 5–7 Tagen Heilfasten mit speziellen ketogenen Säften und gezielter Organunterstützung. Der Trick liegt darin, alle Ausscheidungswege gleichzeitig zu öffnen: Leber und Darm über Bitterstoffe und Mineralstoffe, Nieren über reichlich Flüssigkeit, Lunge über forcierte Atmung, Haut über Schwitzen. So entsteht ein synchronisiertes Entgiftungsorchester statt chaotischer Rückvergiftung. Ein weiterer Game-Changer: Fasten ist ein Marathon, kein Sprint. Die meisten Menschen unterschätzen die Aufbauphase dramatisch. Die Wunder empfehlen bewusst kürzer zu fasten (eine Woche) dafür aber zwei bis drei Wochen hochwertige Aufbauernährung (idealerweise ketogen) zu betreiben. Dadurch bleiben die Fasten-Effekte nicht nur stabil, sondern vertiefen sich über Monate. Viele Teilnehmer spüren die Vorteile noch 4–6 Monate später und wissen dann: jetzt wird es Zeit für die zweite Kur. Kontraindikationen werden klar benannt: Wachstum, Schwangerschaft, Stillzeit, akute Infekte, zehrende Erkrankungen und Essstörungen. Aber für alle anderen – besonders für Menschen mit Stoffwechselproblemen, Herz-Kreislauf-Erkrankungen, Fettleber oder Zivilisationserkrankungen – ist Heilfasten ein bewährtes und hocheffektives Werkzeug. Was du lernst

Wie verändert Keimung eigentlich unser Essen – und was passiert dabei im Detail im Korn? In dieser Folge sprechen wir mit Nina Wartbichler und Manfred Hirschhofer von Keimkraft über die Prozesse hinter vorgekeimten Lebensmitteln. Wir schauen darauf, wie Enzyme aktiviert werden, Antinährstoffe abgebaut werden und warum sich dadurch nicht nur die Nährstoffverfügbarkeit, sondern auch Geschmack und Verträglichkeit spürbar verändern können. Dabei geht es auch um die Frage, warum viele Getreideprodukte heute schwerer verdaulich sind als nötig – und welche Rolle Verarbeitung dabei spielt. Keimung wird so vom simplen Küchentrick zu einem spannenden Ansatz für eine bewusstere, bekömmlichere Ernährung. Eine Folge für alle, die verstehen wollen, wie viel Einfluss Verarbeitung auf unser Essen hat – und warum genau darin ein oft unterschätzter Hebel für die Ernährung der Zukunft liegt.

In this episode of The Poultry Nutrition Blackbelt Podcast, Laura Guarás, RD&A Manager at Kerry, explains how alpha-galactosidase enzymes improve the nutritional value of soybean meal in poultry diets. She explores galactooligosaccharides, nutrient availability, multi-enzyme strategies, and advances in bioengineering that improve enzyme stability and performance in feed systems. Laura also highlights practical implications for feed efficiency and ingredient variability. Listen now on all major platforms!“Alpha-galactosidase supplementation improves digestibility of soybean carbohydrates, supporting better gut conditions, more consistent feed conversion, and improved utilization of soybean meal in poultry diets.”Meet the guest: Laura Guarás is an RD&A Manager at Kerry, specializing in enzyme innovation for human, pet, and animal nutrition. Her work focuses on enzymology, carbohydrate-degrading enzymes, and applied research that improves digestibility, functionality, and sustainability in feed systems. Laura collaborates with global teams to develop data-driven enzyme solutions that enhance feed performance and nutrient utilization in modern poultry nutrition systems. Liked this one? Don't stop now — Here's what we think you'll love!What you'll learn:(00:00) Highlight(01:35) Introduction(02:21) Alpha-galactosidase basics(05:16) Soybean energy release(07:00) Oligosaccharide variability(07:58) Multi-enzyme strategy(09:12) Enzyme source differences(12:57) Closing thoughtsThe Poultry Nutrition Blackbelt Podcast is trusted and supported by innovative companies like: Kerry* Kemin* Fortiva- Poultry Science Association- Anitox- DietForge

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Tomaten im Kühlschrank – praktisch, aber geschmacklich eine schlechte Idee. In dieser Folge von 120 Sekunden Deluxe geht es um ein kleines Küchengeheimnis: Warum verlieren Tomaten im Kühlschrank einen großen Teil ihres Aromas? Du erfährst, welche Rolle Aromastoffe, Enzyme und Temperatur dabei spielen – und warum eine gekühlte Tomate geschmacklich manchmal eher wie ein Schwarz-Weiß-Foto wirkt. Kurz gesagt: Das Motiv ist noch da, aber die Farben fehlen.

Learn how soaking, sprouting, and moderation in nuts and seeds can preserve enzymes, reduce inflammation, and improve digestion. #RawFoods #Enzymes #HealthyFats #HealthTalks

In nature, enzymes are the catalysts that make much of biology work. They jumpstart chemical reactions that either wouldn't happen, or would happen super slowly. They break down food, build other molecules, extract energy, and more. What if we could harness evolution to engineer designer enzymes that do other specific jobs that benefit us?  Putting that idea into practice changed the game for chemistry, and earned Frances Arnold the Nobel Prize prize in 2018. She called it “directed evolution.” Today, thousands of labs use her methods to coax enzymes into doing things no one ever thought of. She joins Host Flora Lichtman to talk about where she sees this approach going in the future, and the personal evolution that brought her into science. Guest: Dr. Frances Arnold is the Linus Pauling Professor of Chemical Engineering, Bioengineering and Biochemistry at the California Institute of Technology in Pasadena, California.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

#245 - Wir dachten, wir verstehen Fettverbrennung: Hormone an, Enzyme spalten Fett – fertig. Doch beim längeren Fasten passiert etwas völlig anderes: Die klassischen Enzyme werden heruntergefahren und Fettzellen nutzen Autophagie – gemeinsam mit Immunzellen. Was das wirklich bedeutet und was nicht, erfährst du in dieser Episode.

Ananas als Fleischzartmacher, Amylase beim Brotbacken, „Fleischkleber“ im Steak. In dieser Folge von Food Facts sprechen wir mit Prof. Thomas Henle über Enzyme: winzige Werkzeuge der Natur, die biologische Prozesse steuern und bei der Herstellung zahlreicher Lebensmittel eingesetzt werden. Wir reden über die Geschichte, klären, was Enzyme wirklich leisten, wie sie rechtlich reguliert sind und erläutern warum Enzyme letztlich unverzichtbar sind. Außerdem gibt Prof. Henle Einblicke, wie und woran er zum Thema Enzyme lehrt und forscht – von der Vorlesung bis ins Labor.

Thank you for joining us for our 2nd Cabral HouseCall of the weekend!   I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks…   Pati: how do you lower and keep cholesterol low during early menopause and when you have Familial Hypercholesterolemia. I have 315 total /240 LDL/70HDL/50 Trig. I am 5.4 height, 120lb and gluten free and dairy free for 13yrs and eat very low carbs and sugar. Never taken statins because they make my joints hurt but had high cholesterol for years but 300 was my highest. What can I take that can help and what should i eat. Thank you Pati      Anonymous: Hi Dr. Cabral. Just wanted to confirm. Podcast 3576 reviewed a PubMed study that gave a minimum daily dosage of 10,800 FU to obtain desired results. The podcast gave me the impression that your supplement exceeded the 10,800 FU/day since only the 20,000 FU number was given. However, 3 plus does per day would be needed? Please can you clarify? Proteolytic Enzyme supplement. Natto Serving dosage on label is - (20,000 FU/g) 150mg My understanding is Natto amount is 3,000 FU 20,000 FU/g x .150g =3,000 Is this correct?      Ashley: Hi Dr. Cabral, I have a detox meal timing question for you. When I did my last set of the big 5 labs, my health coach told me that it would be OK for me to eat at 8 and 3 instead of 11:30 and 6:30 as I feel much better when I fuel my body in the morning. When I don't, I feel ravenous in the evening. However, the admin in the FB group disagreed and said I shouldn't do that. Can you please clarify and let me know how big of a difference it makes to eat later instead of earlier? I feel like if eating earlier in the day helps me actually stick to the foods I'm supposed to eat and I'm still fasting for the same lengths of time that  it would be OK. If it's a bigger deal than I realize, will you please explain the reasoning? Thanks so much!      Tommy: Hi Dr. C, I'm an IHP who's come a long way with healing, but I feel stuck for the remainder. I've attempted a detox only once in my life. After the 4th day I was so wiped out that I couldn't really even work. I've also got high heavy metals but the protocol causes me such histamine reactions (even at a lower dose) that I just can't see it through. I feel stuck, I play for a soccer team but even training is too hard on my nervous system and leaves me wired. Maybe I should just try gentler detox like sauna and castor oil packs but I'm not sure it will be enough, and the sauna may just deplete me further. I've suffered so much with health and I'm in a better place, but still much work left to do.      Lou: Hi Dr. Cabral, I am 15 and listen to your podcast every morning on the way to school with my mom. I was wondering, what would you say are your 5 favorite books? They dont have to be health books. thanks, Lou    Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right!   - - - Show Notes and Resources: StephenCabral.com/3670 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

In this final episode of the Progesterone Promise series, Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center, breaks down one of the most misunderstood hormones in women's health: progesterone. Progesterone is not “good” or “bad.” It's contextual. In today's world of quick sound bites and social media medicine, hormones are often reduced to oversimplified claims like “progesterone fixes anxiety” or “progesterone causes breast cancer.” The truth? It depends on your body, your stress levels, your liver health, your inflammation, your delivery method, and whether you're using bioidentical progesterone or synthetic progestins.   Citations: 1. Oral Progesterone → First-Pass Metabolism & Allopregnanolone Claim: Oral micronized progesterone undergoes significant hepatic first-pass metabolism, increasing neuroactive metabolites (especially allopregnanolone), which positively modulate GABA-A receptors and produce sedative/anxiolytic effects. Core Evidence: Simon et al., 1993; de Lignières et al., 1995; Freeman et al., 1990 — Oral progesterone produces measurable neuroactive metabolites. Paul & Purdy, 1992; Rupprecht et al., 2001 — Allopregnanolone enhances GABA-A receptor activity. Supports: Sedation variability by route • Neurosteroid generation • GABA-A modulation 2. Sulfation vs 5α-Reduction → Opposing Neurologic Effects Claim: Progesterone metabolites can produce calming (5α-reduced) or excitatory (sulfated) neurologic effects depending on enzyme routing. Core Evidence: Majewska et al., 1990 — Pregnenolone sulfate negatively modulates GABA-A. Wu et al., 1991 — Sulfated neurosteroids enhance NMDA signaling. Schumacher et al., 2007; Reddy, 2010 — Pathway reviews of sulfation vs 5α-reduction. Supports: Reverse responding hypothesis • Divergent neurologic experiences • Enzyme-dependent effects 3. Stress & Enzyme Modulation Claim: Chronic stress alters HPA axis tone and hepatic enzyme expression, influencing steroid metabolism balance. Core Evidence: McEwen, 1998 — Allostatic load model. Charmandari et al., 2005 — Cortisol's systemic regulatory effects. Zanger & Schwab, 2013; Gibson & Skett, 2001 — Stress alters cytochrome P450 expression. Supports: Stress-biased metabolism • Context-dependent hormone response 4. Breast Tissue Signaling & Context Claim: Progesterone influences mammary differentiation and interacts with estrogen signaling in context-dependent ways. Core Evidence: Brisken & O'Malley, 2010 — Progesterone receptor biology in breast tissue. Beleut et al., 2010 — RANKL mediates progesterone-driven proliferation. Hofseth et al., 1999 — PR-ER signaling interaction. Stanczyk & Bhavnani, 2014 — Natural vs synthetic differences in breast effects. Supports: Lobuloalveolar differentiation • RANKL pathway • Context-dependent proliferation 5. Synthetic Progestins vs Bioidentical Progesterone Claim: Synthetic progestins differ structurally and bind off-target receptors, producing distinct tissue effects. Core Evidence: Stanczyk et al., 2013 — Receptor binding differences. Sitruk-Ware, 2004 — Biologic comparisons. Chlebowski et al., 2003 (WHI) — Breast cancer signal with CEE + MPA. Supports: Structural divergence • Receptor-level differences • WHI clarification 6. Route of Delivery Differences Claim: Oral, vaginal, transdermal, and sublingual progesterone produce distinct pharmacokinetic profiles and tissue targeting. Core Evidence: Simon, 1995 — Oral vs vaginal PK comparison. Cicinelli et al., 2000 — “First uterine pass effect.” Wren et al., 2003 — Route-dependent systemic levels. Supports: Uterine targeting • Neurosteroid variability • Sedation differences 7. Progesterone, PMS & Migraine Claim: Neurosteroid fluctuations influence GABAergic tone and may contribute to PMS and migraine susceptibility. Core Evidence: Backstrom et al., 2011 — Allopregnanolone fluctuations in PMS. Reddy & Rogawski, 2002 — Neurosteroids and seizure threshold. Martin & Behbehani, 2001 — Hormonal fluctuations and migraine. Supports: Luteal neurosteroid shifts • GABA instability • Migraine association   Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.  

This podcast discusses domestic violence. Sit this one out if you need to Many of us are enraged, shocked, and paralysed by the unfolding information from the JE files. Many of us are also dismayed at the continuing epidemic of domestic violence and murder-by-partner. What do we do? How can we help change things? We can learn how to be an ally in our own communities and circles better. Outrage and sadness must be used as springboards for action, I truly believe it. I'm joined by counsellor and author Patricia Gordon Stevens to talk about domestic and partner violence — a subject too often minimised, despite affecting 25% of women in some of the world's wealthiest countries. We explore why silence and discomfort only deepen the harm, and why education, community, and care matter so deeply.In this conversation, we cover:Why the moment a woman chooses to leave is often the most dangerous timeHow coercive control can appear long before physical violence doesThe subtle red flags friends, families, and colleagues can look forHow to ask caring, non-judgmental questions that keep the connection openWhy Patricia chose fiction (Madness in Memphis) to build empathy that leads to actionThe role men can play in calling out harmful behaviour and changing culture locallyThis episode is confronting, but it's also hopeful. Change doesn't start with grand gestures — it starts with noticing, staying connected, and showing up for the women in our lives.I hope you find it useful and helpful as I did, Alexx, your host. Fancy a few more podcasts we've done over the years, related to this one?Show #137: Dr Sherrie Campbell on cutting ties with toxic family membersShow #359 Dr Karin Luise – Writing New Personal Stories and Learning to Tune InSupport is availableIf this article has raised concerns for you or someone you know, help is available.1800 RESPECT (1800 737 732) – Australia's national domestic, family and sexual violence counselling, information and support service. Available 24/7 via phone or online chat.Lifeline (13 11 14) – 24/7 crisis support and suicide prevention.Beyond Blue (1300 22 4636) – Support for anxiety, depression and mental health concerns.Relationships Australia (1300 364 277) – Counselling and relationship support services.Men's Referral Service (1300 766 491) – Support for men concerned about their behaviour or affected by family violence.Kids Helpline (1800 551 800) – 24/7 counselling support for young people aged 5–25.If you are in immediate danger, call 000.You can also find local support services via www.1800respect.org.auWant to learn more about this week's guest? Website: www.patriciagordonstevens.comInstagram: https://www.instagram.com/patriciagordonstevensauthor Facebook: https://www.facebook.com/patriciagordonstevensauthor Book: https://bit.ly/4aJE0Ve Thank you to this month's show partners for joining us to help you make your low tox swaps! @ediblebeautyau is here with 30% off site-wide! My top reco's? The Super Stem Cell concentrate serum, Exotic goddess serum, Enzyme peel or microexfoliant for some healthy skin regeneration! Or the new up-sized sunscreen in 200g to carry you the rest of summer. Enjoy! CODE: LOWTOXLIFE. @ausclimate is our major partner giving you 10% off their range for the whole of 2026, with brilliant Winix Air Purifiers, the best Dehumidifiers I've ever used and their new energy-efficient heating, air-circulating and cooling range. code LOWTOXLIFE (also works over and above their sales - pro tip!) https://bit.ly/ShopAusclimateBe sure to join me on Instagram @lowtoxlife and tag me with your shares and AHAs if something resonated! I love to see your thoughts, genuinely! Hosted on Acast. See acast.com/privacy for more information.

Concluding our “New Year, More Me” theme, we are invited to ponder from a 3rd angle:What if better health were not an “added” thing to do, but a more strategic approach to the way we do it?”This week, I am chatting with Dr John La Puma, a medical doctor and trained chef, about the “Indoor Epidemic”, a topic he is bringing to life through his upcoming 8th book.John shares why most of us are indoors for about 93% of our time, and how repurposing just two to five hours a week of the time you already spend outside can shift sleep, stress, mood, focus and even appetite signals. Now, most of us ‘know' that lots of indoor time and artificially lit environments are bad for our health, or we've seen the alarming stats on a reel or research quote, but the action and change part? That's often harder and this show is here to change that. We cover simple ideas you can try right away and break down a daily, monthly, and annual framework to achieve incredible health results. The way we use our outdoor time more strategically will show us gains in sleep quality, focus, blood pressure and inflammation. If you feel tired, wired, or stuck on screens, this episode is a warm nudge to change up your outdoor time for the better and feel more like you.Pre-order John's new book - I've loved it. So easy and extremely empowering for anyone who finds the habits you ‘know' are better, but yet you can't quite seem to get things going. Enjoy the show, AlexxFancy a few more podcasts we've done over the years, related to this one?Show #323 – How The Light Spectrum Affects Us For Better Or Worse, With Daniel EbbettShow #465. The practical path to a Brain that Breathes with Jodi WilsonWant to learn more about this week's guest? drjohnlapuma.com indoorepidemic.com instagram.com/johnlapuma youtube.com/drjohnlapuma Book: https://bit.ly/4ahDiOe Thank you to this month's show partners for joining us to help you make your low tox swaps! @jules_stonesoup has been teaching people to cook joyfully and with foods that cultivate health and vitality for over 15 years. Head to bit.ly/joyfulcook20 and use code LOWTOXLIFE to do Jules' next program at 20% off + 2 friends do it free! 20mins a week, 6 months, for less overwhelm, waste and cost, and increased vitality, variety and deliciousness. Sold!@ediblebeautyau is here with 30% off site-wide! My top reco's? The Super Stem Cell concentrate serum, Exotic goddess serum, Enzyme peel or microexfoliant for some healthy skin regeneration! Or the new up-sized sunscreen in 200g to carry you the rest of summer. Enjoy! CODE: LOWTOXLIFE. @ausclimate is our major partner giving you 10% off their range for the whole of 2026, with brilliant Winix Air Purifiers, the best Dehumidifiers I've ever used and their new energy-efficient heating, air-circulating and cooling range. code LOWTOXLIFE (also works over and above their sales - pro tip!) https://bit.ly/ShopAusclimateBe sure to join me on Instagram @lowtoxlife and tag me with your shares and AHAs if something resonated! I love to see your thoughts, genuinely! Want to support the Low Tox Life podcast? Free option: Leave a 5 star review wherever you listen to Low Tox Life - thanks SO much! Paid + Member PERKS: Join the Low Tox Club - monthly practitioner live masterclasses, a suite of low tox store discounts from around the world and the most supportive and lovely chat group on all low tox topics on the internet: Check it out and join here for just the price of a coffee per month! Hosted on Acast. See acast.com/privacy for more information.

In this episode of The Pet Food Science Podcast Show – Equine, Dr. Peter Huntington, Director of Nutrition at Kentucky Equine Research, explains the role of omega-3 and omega-6 fatty acids in equine nutrition. He clarifies differences between short-chain and long-chain fatty acids, discusses inflammation, metabolism, and common misconceptions around oils. Dr. Huntington also explores practical feeding strategies, research gaps, and where current evidence is strongest. Learn science-based insights to improve equine feeding decisions. Listen now on all major platforms!“Not all omega-6 fatty acids are pro-inflammatory, and some play essential roles in tissue repair and healing.”Meet the guest: Dr. Peter Huntington earned his veterinary degree from the University of Melbourne and has spent decades advancing equine nutrition science. As Director of Nutrition at Kentucky Equine Research, his work focuses on fatty acids, inflammation, metabolism, and evidence-based feeding strategies for horses. His experience spans research, consulting, and education within the equine industry. Liked this one? Don't stop now — Here's what we think you'll love!Don't miss the chance to be part of the Pet Food Inner Circle!Join now and connect with leading experts in pet nutrition: https://petfoodinnercircle.com/What will you learn:(00:00) Highlight(00:53) Introduction(05:43) Omega fatty acids(07:38) Enzyme competition(11:30) Long chain importance(14:08) Health applications(18:34) Reproduction focus(39:18) Final QuestionsThe Pet Food Science Podcast Show is trusted and supported by innovative companies like:* Kemin* Trouw Nutrition- Biorigin- DietForge

  In this week's episode, Dr. Haley discusses a product she's been using for almost a decade, Glisodin Skin.    She speaks with Francois Vix, who has spent over twenty years helping some of the most respected beauty brands expand globally. When he founded Laboratoires Isocell, he introduced a bio-active form of SOD (SuperOxide Dismutase) to the world, a breakthrough that stands out after more than 20 clinical trials. His journey building GliSODin Skin Nutrients, now in over 50 countries, highlights how targeted nutrition can support skin health from within.   We discuss how the skin ages from the inside out and how supplements can help achieve healthy skin, clear skin with acne, address rosacea, vitiligo, melasma, and so much more.     TIMESTAMPS: 1:45 – Skin Health Starts From the Inside Out 2:10 – How Glycine Skin Was Founded by Immunologists 3:00 – Medical & Scientific Roots of the Brand 4:00 – Improving Energy, Inflammation & Quality of Life 5:00 – How Dr. Jen Discovered Glycine Skin 6:00 – Nutrition, Supplements & Skin Health Explained 7:00 – What Is Superoxide Dismutase (SOD)? 8:00 – Why SOD Is Called the "Enzyme of Life" 9:00 – Oxygen, Free Radicals & Cellular Damage 10:00 – How SOD Protects Cells From Oxidative Stress 11:00 – Antioxidant, Anti-Inflammatory & Immune Benefits 12:00 – How Internal Antioxidants Work 24/7 13:00 – Skin Diseases, Immunity & Inflammation 14:00 – Photoprotection, Pigmentation & Skin Clarity 15:00 – How Glycine Skin Supports Melasma & Vitiligo 16:00 – Immune Modulation vs Immune Stimulation 17:00 – Overview of Glycine Skin Supplement Options 18:00 – Pure Enzyme Formula: Who It's For 19:00 – Recovery, Inflammation & Athletic Performance 20:00 – Anti-Aging Formula: Skin Texture, Glow & Elasticity 21:00 – Skin Brightening Formula: Melasma & Hyperpigmentation 22:00 – Clinical Dosages vs Under-Dosed Supplements 23:00 – Acne, Laser Treatments & Pigmentation Rebound 24:00 – Seasonal Use: Brightening vs Anti-Aging 25:00 – Phospholipids, Brain Health & Energy 26:00 – Cognitive Benefits & Overall Wellness 27:00 – Gluten, Gliadin & Safety Explained 28:00 – Scientific Studies & Where to Learn More 29:00 – Why Long-Standing Supplements Matter More Than Trends     https://www.glisodin.com/ - Use Code DRJEN2026 for 20% off your order!   Instagram: @glisodin_skin   Watch this episode on The Radiance revealed YouTube Channel:     PRODUCTS / RESOURCES:   Follow Dr. Jen Haley on Instagram @drjenhaley - instagram.com/drjenhaley Connect on LinkedIn:  http://linkedin.com/in/jennifer-haley-md-faad-a4283b46 Book a consultation with Dr. Haley here:  https://app.minnect.com/expert/DrJenHaley Dr. Haley's favorite skincare:  https://www.alumiermd.com?code=5HUKRDKW Dr. Haley's favorite supplements (15% discount): https://us.fullscript.com/welcome/hhaley   #radiancerevealedpodcast

If you want more brain space and less pressure in your day, this Low Tox Life episode is for you.I am joined by author Jodi Wilson, who wrote her new book “A Brain That Breathes” after years of writing, parenting, and pushing through burnout. Jodi noticed something big - modern life asks too much from our brains. We are always reachable, always scrolling, and always deciding. No wonder we feel foggy, edgy, and done.Jodi shares a powerful idea: we do not always need more tools or more “self-care and it definitely does not need to ‘cost us more' to practise it.” We often need subtraction. She calls it breathing space - small moments of downtime that help your nervous system settle and help your brain declutter.You will hear about “soft fascination,” a science-backed reset that happens when your attention is gently held by simple things - a walk without headphones, the ocean, trees, clouds, shower water, or bubbles in the sink. In these moments, your brain gets space to sort thoughts, ease stress, and untangle stuck ideas. Jodi also shares easy ways to protect your mornings, create a calmer evening routine, and use a deep sigh as a fast reset.This is not about fixing yourself. It is about coming home to what you need today - and choosing what is enough.I hope you love it as much as I love that this is out in the world for you, Alexx Stuart, your host xFancy a few more podcasts we've done over the years, related to this one?Show #367 Burn Out and Powering Life Differently with Dr Neha SangwanShow #390 Somatics: How to Make your Journey Real and True with Irene Lyon, MSc.Show #405 It's not you, it's your nervous system: How to tell the difference with Jessica MaguireShow #464. Too busy or scared to feel everything? Dr Jenn Rapkin explains the health benefits we're missing and how to reconnect.Want to learn more about this week's guest? Website: Practisingsimplicity.substack.comInstagram: https://www.instagram.com/practisingsimplicity Book: https://bit.ly/4r7j4fU Thank you to this month's show partners for joining us to help you make your low tox swaps! @jules_stonesoup has been teaching people to cook joyfully and with foods that cultivate health and vitality for over 15 years. Head to bit.ly/joyfulcook20 and use code LOWTOXLIFE to do Jules' next program at 20% off + 2 friends do it free! 20mins a week, 6 months, for less overwhelm, waste and cost, and increased vitality, variety and deliciousness. Sold!@ediblebeautyau is here with 30% off site-wide! My top reco's? The Super Stem Cell concentrate serum, Exotic goddess serum, Enzyme peel or microexfoliant for some healthy skin regeneration! Or the new up-sized sunscreen in 200g to carry you the rest of summer. Enjoy! CODE: LOWTOXLIFE. https://bit.ly/Edible_Beauty@ausclimate is our major partner giving you 10% off their range for the whole of 2026, with brilliant Winix Air Purifiers, the best Dehumidifiers I've ever used and their new energy-efficient heating, air-circulating and cooling range. code LOWTOXLIFE (also works over and above their sales - pro tip!) https://bit.ly/ShopAusclimateBe sure to join me on Instagram @lowtoxlife and tag me with your shares and AHAs if something resonated! I love to see your thoughts, genuinely! Hosted on Acast. See acast.com/privacy for more information.

In this episode of The Poultry Nutrition Blackbelt Podcast, Dr. Sami Dridi from the University of Arkansas explains the molecular and physiological impact of beta mannan on poultry health and performance. He breaks down how beta mannan triggers inflammation, affects gut integrity, and reduces feed efficiency, and he shares research on how beta mannanase can counter these challenges. Listen now on all major platforms!"Beta mannan creates physiological, immunological, and metabolic challenges that influence overall nutrient use and bird performance."Meet the guest: Dr. Sami Dridi is a Professor at the University of Arkansas, leading the Laboratory of Avian Endocrinology and Molecular Genetics within the Center of Excellence for Poultry Science. His research explores heat stress responses, intestinal integrity, and metabolic disorders such as muscle myopathies in poultry. His recent work examines beta mannan and beta mannanase effects on performance and gut health. Listen to this Poultry Nutrition Blackbelt Podcast episode with Dr. Sami Dridi on all major platforms.Liked this one? Don't stop now — Here's what we think you'll love!What you'll learn:(00:00) Highlight(01:39) Introduction(03:45) Beta mannan effects(05:19) Gut integrity impact(06:57) Enzyme function(07:46) Performance results(10:50) Future applications(13:07) Closing thoughtsThe Poultry Nutrition Blackbelt Podcast is trusted and supported by innovative companies like: BASF* Kemin* Fortiva- Anitox- Poultry Science Association- DietForge

What if your body has been trying to get your attention - through tension, numbness, or stress - but you've been too busy to listen?Enter our first show of 2026 to help usher a new chapter in literally feeling the feels.Dr. Jenn Rapkin is a naturopathic doctor who helps people reconnect with their feelings through body-based care. In this episode, we talk about why many of us learned to "push through" emotions - and what that can cost our health. Jenn shares simple ways to notice feelings in the body (like "hard bubbles" in the chest) and why emotions come in waves. You'll learn gentle steps to build emotional strength, without forcing anything. Jenn also explains when it's best to get professional support, especially if trauma is part of your story. This is a kind, practical chat for real life.Fancy a few more shows related to this one?Show #447 The Biology of Trauma: Uncover, Understand, and Heal with Dr. Aimie ApigianShow #408 What would it look like for you to be completely recovered? Thought Field Therapy with Dr Robert BrayShow #378 Stop trying to ‘control' your emotions, and here's why… with Cedric BertelliShow #240 – Dr Carrie Rigoni: Vagus Nerve Health for Babies, Kids, and ParentsWant to learn more about this week's guest? www.drjennrapkin.com https://www.linkedin.com/in/jenn-rapkin-n-d-42a09ab5/ https://www.facebook.com/profile.php?id=61575991456912 https://www.instagram.com/drjennrapkin/ Book: https://bit.ly/3ZcgtFi Thank you to this month's show partners for joining us to help you make your low tox swaps! @jules_stonesoup has been teaching people to cook joyfully and with foods that cultivate health and vitality for over 15 years. Head to bit.ly/joyfulcook20 and use code LOWTOXLIFE to do Jules' next course at 20% off + 2 friends do it free! 20mins a week, 6 months, for less overwhelm, waste and cost, and increased vitality, variety and deliciousness. Sold! https://bit.ly/joyfulcook20 Our first podcast partner offer of the year with @ediblebeautyau - 30% off site-wide! My top reco's? The Super Stem Cell concentrate serum, Exotic goddess serum, Enzyme peel or microexfoliant for some healthy skin regeneration! Or the new up-sized sunscreen in 200g to carry you the rest of summer. Enjoy! CODE: LOWTOXLIFE. https://bit.ly/Edible_Beauty@ausclimate is our major partner giving you 10% off their range for the whole of 2025, with brilliant Winix Air Purifiers, the best Dehumidifiers I've ever used and their new energy-efficient heating, air-circulating and cooling range. code LOWTOXLIFE (also works over and above their sales - pro tip!) https://bit.ly/ShopAusclimateBe sure to join me on Instagram @lowtoxlife and tag me with your shares and AHAs if something resonated! I love to see your thoughts, genuinely! Want to support the Low Tox Life podcast? Free option: Leave a 5 star review wherever you listen to Low Tox Life - thanks SO much! Paid + Member PERKS: Join the Low Tox Club - monthly practitioner live masterclasses, a suite of low tox store discounts from around the world and the most supportive and lovely chat group on all low tox topics on the internet: Check it out and join here for just the price of a coffee per month! Hosted on Acast. See acast.com/privacy for more information.

Nicola Longo MD, PhD, and Mark Roberts, MDDrs. Longo and Roberts discuss the current status of gene therapies in rare neuromuscular disorders in this eight-part podcast series. This is derived from the symposium that was presented at WORLDSymposium 2025 in San Diego, California on February 4th-7th 2025 and is intended for healthcare professionals only.This podcast includes information about investigational compounds that do not yet have a regulatory approval or authorization for a specific indication. The safety and efficacy of the agents under investigation have not been established and contents of this podcast shall not be used in any manner to directly or indirectly promote or sell the product for unapproved uses.The views, thoughts, and opinions expressed in this presentation belong solely to the author and are subject to change without notice. The contents of this presentation do not constitute an endorsement of any product or indication by Astellas. In this part, Dr. Longo will discuss the current treatment landscape and limitations in lysosomal disorders.Nicola Longo MD, PhDWhat I want to do today, is just place gene replacement therapy within the current landscape of lysosomal storage disorder treatment therapy. Gene therapy obviously has the potential of treating lysosomal disorder to correct the root cause of lysosomal storage disorder. The gene is defective, and what happen is that you can potentially either fix the gene or bypass the lack of the genetic product. But there are already therapies that are existing and are functioning. Obviously, in many cases, the lysosomal disorder is caused by defective production of an enzyme, which is defective.We can either replace the enzyme with enzyme replacement therapy, or provide chaperone for specific mutations that retain the synthesis of the enzyme, that however is not very functional. Another avenue that it is being reported is the utilization of substrate reduction therapy. A substrate accumulates, you prevent the synthesis of the substrate to reduce the accumulation of toxic material. What we know now is that this is not enough to produce many lysosomal disorders. In many cases, the lysosomal disorder result sometime in impairment of intracellular trafficking, and sometime in the function of other organelles.At the end, it results in the activation of the macrophagic system and inflammation. Already we have some therapy acting at this level. The end result of lysosomal storage disorder, there will be cell suffering and cell death, leading to a progression of the disease, and morbidity and mortality. Now, what therapy do we have available already? Obviously, hematopoietic stem cell transplantation has been around for quite some time.It has been the same thing that we do with gene therapy, except that instead of reintroducing the gene of the subject, we place gene of a subject who is not affected of the disease. This therapy has been proven effective in cases of MPS-1 and alpha-mannosidosis. But in many cases this has to be given way before symptoms start to be affected.Enzyme replacement therapy has been around for quite some time, starting with Gaucher disease, and now that it is available for a list of diseases that are there, so it's like Fabry, Gaucher, Pompe, different types of mucopolysaccharidosis, alpha-mannosidosis, acid lipase deficiency, 1 neuronal ceroid lipofuscinosis, and Niemann-Pick type A and B.Obviously the advantage of this therapy, they give back the enzyme that it is defective. But the disadvantage that many time they cannot enter specialized areas such as the brain. There is already the second generation of enzyme replacement therapy that it is available. With this second generation, some of the newer drugs are more effective in terms of cellular uptake, or in terms of having a prolonged half-life and prolonged activity.Then there are pharmacological chaperone therapy, and the one which is FDA approved is migalastat for Fabry disease, under study is ambroxol for Gaucher disease. The disadvantage of this therapy that only a selected number of mutations respond to this therapy.Substrate reduction therapy has been introduced for Gaucher disease many years ago with miglustat, and it was followed by eliglustat. Both of them are effective, and some of them more effective than other, simply because of the fewer side effects of eliglustat as compared to miglustat. But at the same time, eliglustat does not pass the blood brain barrier.Finally, the newer agents that are already administered, N-acetyl-L-leucine and arimoclomol, both approved for Niemann-Pick type C, they act more on the downstream effect of the lysosomal storage disorder, either by stabilizing neuronal cell activity or by reducing the inflammation that is present in the brain.In the next part, Dr. Longo will discuss gene replacement therapy in lysosomal disorders.

Connect with us via text! It's finally here -- the end of the year -- and with it comes a stacked calendar for DERMASCOPE. Check out the December issue for the 2025 cover contest winner reveal and other educational goodies, register for "Peeling Explained: Chemical, Enzyme, Physical & Biological Approaches", a webinar presented by Dr. Schrammek USA, and help us close out our anniversary year and season five of the podcast. Thanks for celebrating with us, and don't forget to take advantage of all December has to offer! Follow DERMASCOPE:Instagram: @dermascopeFacebook: facebook.com/dermascopePinterest: @dermascopeTikTok: @dermascopeAdditional Links:Visit our website.Learn more about this podcast.Subscribe to the magazine.Read the December 2025 issue. Register for the Schrammek webinar. 

Join Dr. Daniel Simon as he explores the groundbreaking collaboration between Dr. Sanford Markowitz and Dr. Andrew Pieper. Discover how their combined expertise in cancer genetics and psychiatry is leading to innovative approaches that tackle Alzheimer's and traumatic brain injury, providing hope and insight to those affected by these devastating conditions.Learn more about Sanford Markowitz, MD, PhDLearn more about Andrew Pieper, MD, PhDNEW! View our Science@UH video podcast on YouTubeLearn more about the University Hospitals Research & Education Institute

Thank you for joining us for our 2nd Cabral HouseCall of the weekend!   I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks…   Lynette: I have Celiac Disease and worry about cross-contamination when eating at restaurants or friends' homes. People have suggested taking a gluten digestive enzyme, but I don't want to digest gluten. Is there anything I can take prior to eating that would rid my body of gluten, should I unknowingly come into contact with it? I'm a "silent celiac" so don't experience immediate GI upset, but instead suffer joint pain, headaches, and skin issues afterward. Living gluten-free out in the world is tough, so any suggestions to make things easier and safer are appreciated. Thanks!                                          Anonymous: I received a complimentary bottle of CBD Gummies -- thanks! Are there any contraindications with taking them? I'm thinking about them for my older parents, who are on the typical American old-age pharmaceuticals, including high blood pressure medication, statins, and Gabapentin. Will the gummies help with general aches and pains? Thank you.                                                                                                                                                                                            Sarah: I did labs through Equilife and found that my testosterone and DHEA were significantly low. For reference, I am a 49 year-old perimenopausal female. I started using about 8 mg of DHEA orally daily. (at that point I had 25 mg capsules I was splitting) Within three days of starting I had some longer lasting cystic acne on my face starting to appear. I gave it a few weeks to resolve and then began 25 mg of 7 keto DHEA daily and have had no acne breakouts at all. On my call with my IHP through Equilife to follow up from the labs, I was told that 7 keto DHEA is the same as regular DHEA and is likely just a marketing tool. Can you tell me why I reacted significantly different to the 7 keto DHEA? Several companies, some quite reputable sell it, do you recommend it in my case?                                              Anonymous: Hello, I appreciate the work you do, and would like your input to help me make a purchasing decision. I wanted to buy some Japanese selvedge jeans and notice they contain 2% Polyurethane. I had difficulty establishing whether the use of Polyurethane in clothing is harmful and wanted to know if you could direct me to resources which could provide me with more insight on this topic? Please let me know.                                                                                               Anonymous: I struggle with brain fog and low energy in the afternoons, even though I get enough sleep. Could this be related to blood sugar balance, and if so, what are some easy ways to stabilize it throughout the day?               Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3558 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

durée : 00:05:08 - Avec sciences - par : Alexandra Delbot - Une nouvelle étude montre que l'enzyme HSL, connue pour libérer les graisses, agit aussi le stockage des lipides. Selon sa localisation, elle jouerait des rôles différents. Une découverte qui permet une meilleure compréhension de la lipodystrophie et de l'obésité.

AABP executive Director Dr. Fred Gingrich reviews a paper published in The Bovine Practitioner with two of the authors. Joining today are Dr. Greg Habing, professor in the Department of Preventive Medicine at The Ohio State University College of Veterinary Medicine, and Dr. Emily Nogay, clinical assistant professor at The Ohio State University Large Animal Ambulatory Services.  Salmonella Dublin is a host-adapted and zoonotic pathogen affecting many dairy farms. It can be associated with high morbidity and mortality and is often multi-drug resistant which elevates its importance to dairy farmers and veterinarians. Surveillance and diagnostics are an important aspect of managing diseases in our herds. Nogay reviews available diagnostic tests and the advantages and disadvantages of each one. The ELISA test has a sensitivity of 65%, but is used to screen herds for the disease. The objective of this study was to determine if the four U.S. commercially licensed Salmonella vaccines would result in a positive Salmonella Dublin ELISA test result.  We walk through the results of the paper and discuss some of the findings, including the impact of the vaccines on the serum ELISA results and some potential reasons for the ELISA results after vaccination. Habing discusses future opportunities for research on this disease, including the need for better diagnostic tests, including a PCR test to screen herds.  AABP's peer-reviewed journal, The Bovine Practitioner, publishes original research studies, reviews, case series, and case reports intended to provide clinically relevant research to private practicing veterinarians. It is an open access journal and there are no publication fees for submitting authors. Read more about the journal at this link.  The effect of Salmonella vaccination on Salmonella Dublin blood enzyme-linked immunosorbent assay results. Bov Pract. 2025;59(2), 53-60. https://doi.org/10.21423/bpj20259266

Computation is killing the wet lab—and reshaping enzyme innovation in the process. Maria Fátima Lucas, CEO of ZYMVOL, shares how AI and physics-based simulation shrink enzyme discovery from 100 million sequence variants to fewer than 300 lab-tested hits—cutting timelines, risk, and cost by orders of magnitude.In this episode, Maria unpacks how ZYMVOL is making biocatalysis not just greener, but cheaper and faster—bringing clean chemistry to sectors previously priced out. From Europe's regulatory drivers to a bold product pivot into bio-based melanin, this is a rare look inside a deeptech company scaling with precision, not hype.Tune in for a fresh look at building ventures that last, not just raise.--- Hey Climate Tech enthusiasts! Searching for new podcasts on sustainability? Check out the Leaders on a Mission podcast, where I interview climate tech leaders who are shaking up the industry and bringing us the next big thing in sustainable solutions. Join me for a deep dive into the future of green innovation exploring the highs, lows, and everything in between of pioneering new technologies.Get an exclusive insight into how these leaders started up their journey, and how their cutting edge products will make a real impact.Tune in on…YouTube: https://www.youtube.com/@leadersonamissionNet0Spotify: https://open.spotify.com/show/7o41ubdkzChAzD9C53xH82Apple Podcasts: https://podcasts.apple.com/us/podcast/leaders-on-a-mission/id1532211726…to listen to the latest episodes!Timestamps:00:00 – Clean chemistry = mission02:41 – From pharma to enzymes05:07 – Bootstrapping for 6 years07:03 – AI + physics workflow10:55 – Why cost always wins11:15 – Regulatory bans as tailwind14:52 – End-to-end solution model19:31 – First hits in 3 months23:47 – Enzyme marketplace vision28:42 – Bio-melanin case study35:24 – Fundraising and futureUseful links: ZYMVOL  website: https://zymvol.com/ZYMVOL LinkedIn: https://www.linkedin.com/company/zymvol/Maria Fatima Lucas LinkedIn: https://www.linkedin.com/in/fatimalucas/Leaders on a Mission website: https://cs-partners.net/podcasts/Simon Leich's LinkedIn: https://www.linkedin.com/in/executive-talent-headhunter-agtech-foodtech-agrifoodtech-agritech/

Gesund essen, ohne zu verzichten: so geht's wirklich   Viele Menschen denken, sie ernähren sich bereits gesund. Doch in der Praxis zeigt sich oft: Es gibt einige hartnäckige Fehlannahmen.In dieser Podcastfolge deckt Julia Gruber die häufigsten Denkfehler rund um gesunde Ernährung auf und erklärt, warum eine darmfreundliche Ernährung nicht kompliziert sein muss.Du erfährst, worauf es wirklich ankommt, welche Rolle Fruchtzucker, Kalorien oder Vitamine spielen, und wie du mit wenigen, machbaren Veränderungen grosse Wirkung erzielen kannst.Plus: Tipps zur Umsetzung, wenn du endlich spürbare Ergebnisse für deine Haut, deinen Bauch oder deine Energie möchtest. Highlights

Implications of a mutation in modern humans Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Xiangchun Ju and Svante Pääbo explore the evolutionary implications of a mutation that separates modern humans from ancestral hominins. In this episode, we cover: •[00:00]  •[01:22] Neurobiologist Xiangchun Ju introduces the enzyme adenylosuccinate lyase, or ADSL, and its role in the synthesis of purine. •[02:09] Evolutionary anthropologist Svante Pääbo talks about the discovery of the A429V mutation, which is present in modern humans but not Neanderthals or Denisovans. •[03:38] Ju and Pääbo talk about the methods to humanize mice in order to study the evolutionary importance of the A429V mutation. •[05:04] They explain the results of the behavioral studies of the humanized mice. •[06:27] Pääbo explores the takeaways from the study.  •[08:05] He contextualizes the study alongside other studies of modern human development. •[09:17] Pääbo and Ju list the caveats and limitations of the study. •[10:14] Conclusion. About Our Guests: Xiangchun Ju Postdoctoral scholar Okinawa Institute of Science and Technology Svante Pääbo Director Max Planck Institute for Evolutionary Anthropology View related content here: https://www.pnas.org/doi/10.1073/pnas.2508540122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast  Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter

In this episode, we review the high-yield topic of⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Enzyme Kinetics ⁠from the Pharmacology section.Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets

Could this overlooked gut enzyme be the reason you're still not pregnant?Most women have never even heard of this enzyme, so if you've been chasing answers without success, this hidden factor might finally explain what's going on.In this episode, you'll...-Understand what beta glucuronidase is and why it matters for fertility.-Discover the symptoms and lifestyle factors that increase your risk of imbalance.-Learn simple, practical ways to support gut health, estrogen detox, and better hormone balance.Tune in now to uncover how rebalancing this one enzyme could open the door to the healthy pregnancy you've been longing for.

Gene Mack, CEO and President of Gain Therapeutics, is combining AI-powered drug discovery with the development of allosteric modulators, drugs that bind to unique sites on proteins. The company's AI platform, Magellan, is crucial for accelerating drug discovery by reducing the time for computational screening of potential drug compounds.  Their lead compound is showing promising results as a potential disease-modifying therapy for Parkinson's disease, aiming to halt the progression of the disease rather than just treating symptoms. Gene explains, "So allosteric modulators of protein, it's a bit of a word salad, but what we're trying to achieve here is finding unique binding sites on proteins that are sort of away from the active site of that protein." "So, a lot of physics calculations go into these binding site calculations. The idea is to complete these quickly during the screening of hundreds or thousands of compounds. This process takes 10 to 15 minutes to run a set of computations and determine if a particular molecule is a fit for a specific protein. If that takes 10 or 15 minutes per compound, it's not a very big deal to go to that library if you need to get through billions, trillions of those compounds, and you need that computational speed to really fire up." "We are able to speed up those calculations from, let's say, 10 minutes to milliseconds. You can screen through much larger numbers of compounds and potentially even construct new molecules that are not known to the public domain, which would be a real key innovation." "What we think we have in our lead program, which is GT-02287, another molecule that was discovered through our application of Magellan. What we hope we have in GT-02287 is a disease-modifying approach to Parkinson's. Up until now, the only available treatments for Parkinson's are really just focused on the symptoms and allaying the severity of the symptoms." #Parkinsons #ParkinsonsDisease #AI #DrugDiscovery #GAINtherapeutics #DiseaseModification gaintherapeutics.com Download the transcript here

Gene Mack, CEO and President of Gain Therapeutics, is combining AI-powered drug discovery with the development of allosteric modulators, drugs that bind to unique sites on proteins. The company's AI platform, Magellan, is crucial for accelerating drug discovery by reducing the time for computational screening of potential drug compounds.  Their lead compound is showing promising results as a potential disease-modifying therapy for Parkinson's disease, aiming to halt the progression of the disease rather than just treating symptoms. Gene explains, "So allosteric modulators of protein, it's a bit of a word salad, but what we're trying to achieve here is finding unique binding sites on proteins that are sort of away from the active site of that protein." "So, a lot of physics calculations go into these binding site calculations. The idea is to complete these quickly during the screening of hundreds or thousands of compounds. This process takes 10 to 15 minutes to run a set of computations and determine if a particular molecule is a fit for a specific protein. If that takes 10 or 15 minutes per compound, it's not a very big deal to go to that library if you need to get through billions, trillions of those compounds, and you need that computational speed to really fire up." "We are able to speed up those calculations from, let's say, 10 minutes to milliseconds. You can screen through much larger numbers of compounds and potentially even construct new molecules that are not known to the public domain, which would be a real key innovation." "What we think we have in our lead program, which is GT-02287, another molecule that was discovered through our application of Magellan. What we hope we have in GT-02287 is a disease-modifying approach to Parkinson's. Up until now, the only available treatments for Parkinson's are really just focused on the symptoms and allaying the severity of the symptoms." #Parkinsons #ParkinsonsDisease #AI #DrugDiscovery #GAINtherapeutics #DiseaseModification gaintherapeutics.com  Listen to the podcast here

In this episode of The Poultry Nutrition Blackbelt Podcast, Dr. Bayo Sokale from BASF breaks down the evolving role of β-mannanase in poultry diets. He shares how this enzyme supports both nutrition and gut health, offers tips on applying matrix values, and explores its impact on the immune response. Listen now on all major platforms!"β-mannanase reduces gut viscosity, which helps improve nutrient digestion and supports better intestinal function in poultry diets."Meet the guest: Dr. Bayo Sokale earned his Ph.D. in Poultry Science from Mississippi State University and currently serves as the Technical Lead for Feed Enzymes & Feed Performance Ingredients at BASF North America. With over a decade of experience in the poultry industry, Dr. Sokale specializes in enzyme application, gut health solutions, and diet optimization.Liked this one? Don't stop now — Here's what we think you'll love!What you'll learn:(00:00) Highlight(01:23) Introduction(02:36) Importance of substrate(03:23) Enzyme use strategy(08:30) β-mannanase role(09:32) Gut health impact(16:23) Effects on layers(18:47) Closing thoughtsThe Poultry Nutrition Blackbelt Podcast is trusted and supported by innovative companies like: BASF* Kerry* Kemin- Poultry Science Association- Anitox

What if everything you think you know about supplementation is backwards, and the real secret lies in the enzymatic processes that bodybuilders discovered decades ago? I sit down with Wade Lightheart and Matt Gallant from BiOptimizers who blow my mind with their lab research shows 1200% more amino acid absorption when you combine the right enzymes with protein, why magnesium deficiency is literally rewiring your stress response, and how fixing gut dysfunction - which I've seen in every single anxiety patient among my 160,000 cases - transforms everything from brain fog to systemic inflammation. BIOPTIMIZERS: “ULTIMATE” FOR 10% OFF: ⁠https://bit.ly/4inFfd7 Join the Ultimate Human VIP community for Gary Brecka's proven wellness protocols! https://bit.ly/4ai0Xwg Get Matt Gallant and Wade Lightheart's book, “The Ultimate Nutrition Bible“ here http://bit.ly/4fcvRsC   Listen to "BIOptimizers Awesome Health Podcast" on all your favorite platforms! Website http://bit.ly/457Ju7x Apple Podcasts http://bit.ly/3J63qjP   Connect with Wade Lightheart Website http://bit.ly/4l6CApl YouTube http://bit.ly/3INtZu3 Instagram http://bit.ly/459xSRw TikTok http://bit.ly/46xKt3A Facebook https://bit.ly/3J59Xv8  X http://bit.ly/4kXGtgh LinkedIn http://bit.ly/4mgNNoa Connect with Matt Gallant YouTube http://bit.ly/4oc5nLE Instagram http://bit.ly/3U2DBDF Facebook http://bit.ly/4kUa75P X http://bit.ly/475TbGd LinkedIn http://bit.ly/3UFY29D Thank you to our partners H2TABS: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4hMNdgg BODYHEALTH: “ULTIMATE20” FOR 20% OFF: http://bit.ly/4e5IjsV BAJA GOLD: "ULTIMATE10" FOR 10% OFF: https://bit.ly/3WSBqUa EIGHT SLEEP: SAVE $350 ON THE POD 4 ULTRA WITH CODE “GARY”: https://bit.ly/3WkLd6E COLD LIFE: THE ULTIMATE HUMAN PLUNGE: https://bit.ly/4eULUKp WHOOP: JOIN AND GET 1 FREE MONTH!: https://bit.ly/3VQ0nzW MASA CHIPS: 20% OFF FIRST ORDER: https://bit.ly/40LVY4y VANDY: “ULTIMATE20” FOR 20% OFF: https://bit.ly/49Qr7WE A-GAME: “ULTIMATE15” FOR 15% OFF: http://bit.ly/4kek1ij HAPBEE: FEEL BETTER & PERFORM AT YOUR BEST: https://bit.ly/4a6glfo CARAWAY: “ULTIMATE” FOR 10% OFF: https://bit.ly/3Q1VmkC RHO NUTRITION: “ULTIMATE15” FOR 15% OFF: https://bit.ly/44fFza0 HEALF: 10% OFF YOUR ORDER: https://bit.ly/41HJg6S GO PUFF: GET YOUR FAVORITE SNACK!  ⁠http://bit.ly/4obIFDC⁠ GENETIC TEST: ⁠https://bit.ly/3Yg1Uk9 Connect with Gary Brecka Instagram https://bit.ly/3RPpnFs TikTok https://bit.ly/4coJ8fo YouTube ⁠https://bit.ly/3RPQYX8 X https://bit.ly/3Opc8tf Facebook https://bit.ly/464VA1H LinkedIn https://bit.ly/4hH7Ri2 Website https://bit.ly/4eLDbdU Merch https://bit.ly/4aBpOM1 Newsletter https://bit.ly/47ejrws Ask Gary https://bit.ly/3PEAJuG Timestamps 00:00 Intro 02:36 Creation of Bio Optimizers 12:14 Disruption of Genetic Tendency 14:55 Importance of Taking Digestive Enzymes 26:21 Symptoms of Magnesium & Other Nutrient Deficiencies 32:42 Fixing One's Digestion Before Starting Supplementation 42:13 Concept of NanoVi Machine 31:43 Starting Your Supplementation Journey 50:55 Going Back to Taking Whole Foods 52:29 Gut-Brain Connection 1:02:29 What's Next for Matt and Wade? 1:08:49 Human Optimizing 10-Day Experience 1:15:16 Experience on Different Types of Brain Frequencies  1:17:15 What does it mean to you to be an “Ultimate Human?”  The Ultimate Human with Gary Brecka Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The Content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. Learn more about your ad choices. Visit megaphone.fm/adchoices

John Richardson comes on the show to talk about the pharmaceutical industry and the lies involving cancer.  Can cancer be prevented, even cured, with a naturally occurring enzyme?  Listen and decide for yourself.Long-time show hosts Bob Dunlap, a businessman from North Carolina, and Eric Matheny, a criminal defense attorney in Florida, deliver weekly patriotic brilliance. Here on Maverick Broadcasting Netowrk, the outspoken duo are ready to take it to the next level. America is at a crossroads. Bob and Eric are here to keep people informed about the right directions to go. Catch them every Saturday at noon Eastern as they discuss the important issues of the week.Follow Maverick Broadcasting Network on Pickax to catch the full lineup of shows and breaking news: https://pickax.com/maverickbroadcastingProtect your financial future with precious metals! Get your FREE Gold and Silver Guide from My Gold Guy today and take control of your financial destiny! https://mygoldguy.comIndulge in the finest quality with Freedom First Beef – sous vide, freeze-dried, and ready to savor today or in a decade. Order now using code BOBANDERIC for a 25% discount.  https://freedomfirstbeef.comBe ready for anything life throws your way with The Wellness Company's Medical Emergency Kit. Order today using code BOBANDERIC for a 10% discount at https://twc.health/mbn.Unleash the spirit of liberty in every cup with Supermassive Black Coffee. Order now using code MAVERICK and savor the unparalleled taste of freedom in every patriotic sip. https://supermassiveblackcoffee.com.com

Story at-a-glance Egg white proteins naturally lower blood pressure by releasing peptides that relax blood vessels and boost nitric oxide production without pharmaceutical side effects Research shows egg whites reduced systolic blood pressure by 18 points in just nine days by supporting the body's natural circulation mechanisms Enzyme-treated egg whites maintain blood pressure benefits while eliminating allergic reactions, making them a safe option for people allergic to eggs Pasture-raised, low-linoleic acid eggs provide optimal cardiovascular benefits, while conventional factory-farmed eggs cause inflammation that counteracts many positive effects Combining egg whites with nitric oxide-boosting foods like beets and glycine-rich bone broth maximizes their blood pressure-lowering effects and overall benefits naturally  

In this Jack Westin MCAT Podcast episode, Mike and Molly turn the intimidating world of enzyme kinetics into a step-by-step masterclass you can use on your very next practice exam.What you'll learn- The real meaning of a Michaelis-Menten hyperbolic curve—and why enzyme concentration must stay fixed- How to picture Vmax, kcat, Km, and catalytic efficiency (kcat/Km) without memorizing charts- Rapid hacks for reading a Lineweaver-Burk plot (1/Vmax on the Y-intercept, –1/Km on the X)- Competitive vs. uncompetitive vs. mixed vs. non-competitive inhibition—how each one shifts Vmax, Km and the double-reciprocal graph- Mike & Molly's test-day mnemonics (

Struggling to keep all the rate-law rules and enzyme facts straight? In this Jack Westin MCAT Podcast episode, Mike and Molly break down exactly what the AAMC expects you to know—no fluff, just high-yield kinetics you'll see on Test Day.What we cover in Part 1* Big-picture difference between K (equilibrium) vs k (rate)* The Arrhenius equation & how Ea and T really control reaction speed* How to recognize zeroth, first & second-order rate laws in passages* Why the rate-determining step rules every multi-step mechanism* How enzymes lower activation energy, plus active site basics* Essential vocab: apoenzyme → holoenzyme, cofactors vs coenzymes* The Induced-Fit Model (forget “lock-and-key” oversimplifications)* Fast recall with the LIL HOT enzyme-classification mnemonicBy the end you'll be able to:✅ Write and manipulate rate laws with confidence✅ Predict how temp or catalysts shift reaction speed✅ Decode enzyme names on the fly and spot catalytic tricks the MCAT lovesNext up in Part 2: Michaelis–Menten kinetics, Km/Vmax shortcuts, and inhibitor patterns—so make sure you're subscribed and turn on notifications!Want to learn more? Shoot us a text at 415-855-4435 or email us at podcast@jackwestin.com!

Subscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsWhat's Carol Alt's secret to glowing skin, boundless energy, and youthful vitality at 64? In this episode of Hol+, Dr. Taz MD sits down with the iconic supermodel, entrepreneur, and raw food advocate to reveal the powerful truths behind aging well, naturally. From reversing signs of aging to healing chronic health issues with food, Carol shares how raw nutrition, enzyme therapy, and a deeply holistic lifestyle transformed her health in her 30s, and why she's never looked back.You'll learn the raw, unfiltered truth (pun intended) about how Carol rebuilt her body from the inside out, the rituals that keep her glowing into her 60s, and her philosophy that the closer you eat to God, the better your body functions. From raw tiramisu to trail mix, from detox protocols to spiritual mindset shifts, this is a must-watch episode for anyone who wants to age with grace, energy, and empowerment, without surgery or shortcuts.Carol opens up about:• The moment she knew cooked food was draining her life force• Her enzyme-rich daily routine that supports digestion, skin, and energy• How she healed chronic health problems (like candida) by going raw• Why beauty really does start in your 20s, and what to do now if you didn't know• Her take on fats, fasting, juicing, and eating with intention• How mindset, discipline, and food all fuel her glow at 64If you're struggling with fatigue, weight gain, digestive issues, or you just want to feel better and glow naturally, this conversation will make you rethink what you eat, and how you age.Topics Covered:• Raw food for beauty, energy, and gut health• Enzyme therapy and why it matters after 30• Detoxing safely and naturally through food• How to rebuild your body at any age• Fats, oils, and misunderstood nutrients• The mind-body-spirit connection in aging• Redefining what 64 can look, and feel,likeThank you to our sponsor: OneSkinGet 15% off your first order with the code DRTAZ at oneskin.co/drtazAbout Carol AltDubbed The Face by The Fashion Industry, Carol Alt is a pioneer and chameleon in the fashion, entertainment and Health industries; she is constantly on the lookout for new challenges. Since her days as the world's most renowned Supermodel, Carol has gone on to be multi-award winning actor, successful entrepreneur, best-selling author on Raw Food and Nutrition, and the host of A Healthy You & Carol Alt on FOX News Channel.Stay ConnectedConnect further to Hol+ at https://holplus.co/- Don't forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsFollow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Join the conversation on X: https://x.com/@drtazmdTikTok: https://www.tiktok.com/@drtazmdFacebook: https://www.facebook.com/drtazmd/Follow Carol Alt on Instagramhttps://www.instagram.com/modelcarolalt/Host & Production TeamHost: Dr. Taz; Produced by Rainbow Creative (Executive Producer: Matthew Jones; Lead Producer: Lauren Feighan; Editors: Jeremiah Schultz and Patrick Edwards)Don't forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+00:00 The Body Reflects Your Habits01:23 Raw Food vs Diet Trends04:50 Carol's Journey to Healing with Raw Food09:03 The Biggest Health Mistakes Before Age 3610:33 What Cooking Does to Food and Enzymes15:00 Raw Proteins, Sprouting, and Going Beyond Vegan 19:11 Juicing, Detox, and Rebuilding the Body25:24 The Truth About Fats, Oils, and Skin Health36:33 Aging After 60 and Staying Energized48:17 Eat Close to Nature - Carol's Final Message

"That's the one I went to."

The latest price moves and insights with Jennifer Sanasie and Enzyme founder Mona El Isa.To get the show every day, follow the podcast here.Enzyme founder Mona El Isa joins CoinDesk to discuss the current "strange bear market" in the crypto space, with a few assets remaining close to their highs while the broader market experiences significant underperformance. Plus, potential of a DeFi summer and the state of M&A in the crypto industry.This content should not be construed or relied upon as investment advice. It is for entertainment and general information purposes.-This episode was hosted by Jennifer Sanasie. “Markets Daily” is produced by Jennifer Sanasie and edited by Victor Chen.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Sometimes, feeling “off” isn't just about stress or aging—it could be your gut trying to tell you something. Your digestion plays a bigger role than you might think, influencing everything from your energy and hormones to your mood and even your sex life. Steven Wright, Functional Medicine Expert and Founder of The Healthy Gut Company, is back to share why gut health is the key to feeling like yourself again. We get into the hidden culprits behind bloating, brain fog, and even intimacy struggles—because, yes, your gut impacts that too! Turns out, simple changes can make a big difference. Steven breaks down how digestive enzymes can transform your digestion, why butyrate is a game-changer for gut healing, and what all of this has to do with hormone balance. We even tackle a topic most people avoid—how gut health can impact erectile function and what men can do about it. If you've been dealing with stubborn symptoms and wondering what's really going on, you won't want to miss this one. Taking care of your gut is one of the best ways to support your body, and it doesn't have to be complicated. And if menopause symptoms have been throwing you for a loop, I've got you—check out my Magic Menopause Program and let's get you back to feeling amazing!   Key Timestamps: [00:00:00] Introduction. [00:04:02] Gut health journey and solutions. [00:08:21] Beyond the everything's toxic paradigm. [00:12:01] Enzyme production and digestion. [00:15:00] Digestive health and food variety. [00:19:42] Intimacy and digestive health. [00:22:02] Enzyme dosage and sensitivity. [00:24:11] Digestive enzymes and aging. [00:27:39] Importance of butyrate for health. [00:32:08] Butyrate and gut health. [00:34:02] Tributyrate vs. Sodium Butyrate. [00:40:20] Erectile dysfunction and gut health. [00:45:49] Estrogen and gut health connection. [00:47:53] Importance of gut health.   Memorable Quotes: "It's not the foods that are wrong, the foods are not the enemy, it's the fact that your body is not capable of digesting these normal everyday foods and we should be looking upstream to what's going on with the body instead of blaming the foods." [00:12:05] – Steven Wright "If it doesn't work, most of the time you have a gut issue that you need to address along with the BHRT. And if you do those things together, everything you're wanting from your program will start to come together." [00:46:08] – Steven Wright   Links Mentioned:  Magic Menopause Program: https://order.magicmenopause.com/ Healthy Gut (Code: DrAnna for 15% off): https://healthygut.com/dranna Holozyme: https://healthygut.com/drannaholo Tri-X: https://healthygut.com/drannatrix HCL: https://healthygut.com/drannahcl HoloImmune: https://healthygut.com/drannaimmune Mag-HP: https://healthygut.com/drannamaghp Beserene Bundle: https://healthygut.com/drannaserene HistaHarmony: https://healthygut.com/drannahh   Connect with Steven Wright: Website: https://healthygut.com/ Instagram: https://www.instagram.com/healthygutco/   Connect with Dr. Anna Cabeca: Website: https://drannacabeca.com/pages/show Instagram: https://www.instagram.com/thegirlfrienddoctor/ YouTube: https://www.youtube.com/@thegirlfrienddoctor TikTok: https://www.tiktok.com/@drannacabeca   Produced by Evolved Podcasting: www.evolvedpodcasting.com

Egal ob Forschung zu Medikamenten oder zur Frage, wie schnell sich das Virus in der Bevölkerung ausbreitet: Studien zum Coronavirus kamen während der Pandemie hauptsächlich aus Ländern wie UK oder Israel. Was müsste anders laufen beim nächsten Mal? Daniela Remus und Korinna Hennig aus der NDR Info Wissenschaftsredaktion fragen in dieser Folge, wie Wissen über einen neuen Erreger gewonnen wird, warum man eigentlich so wenig über Kinder weiß und was der Datenschutz mit all dem zu tun hat. “Ein Kollege hat mal ausgerechnet, dass allein für das Antragsverfahren für eine Studie 440 Arbeitsstunden aufzuwenden sind”, sagt der Intensivmediziner Stefan Kluge vom UKE in Hamburg. Doch es gibt auch gute Nachrichten: Seit der Corona-Zeit können Erkenntnisse über Krankheitserreger auch aus dem Abwasser gewonnen werden. Außerdem in dieser Folge: Die WissenschaftlerInnen Berit Lange, Christian Drosten, Silvia Thun, Philipp Wild, Emanuel Wyler und der RKI-Präsident Lars Schaade. REACT-Studie vom Imperial College London und Ipsos MORI aus England: https://www.reactstudy.org/ NAKO, Deutschlands größte Langzeitstudie zur Erforschung von Volkskrankheiten: https://nako.de/ Studie „Gesundheit in Deutschland“ vom Robert Koch-Institut (RKI): https://gesundheit-in-deutschland.de/de MuSPAD, Multilokale und Serielle Prävalenzstudie zu Antikörpern gegen (respiratorische) Infektionserkrankungen Deutschland, Helmholtz-Zentrum für Infektionsforschung (HZI): https://muspad.de/ Recovery-Studie, weltweit größte klinische Studie zur Behandlung von Covid-19: https://www.recoverytrial.net/ Emanuel Wyler et.al.: Studie über die Entdeckung neuartiger Viren und Enzyme durch Abwassermonitoring: https://www.sciencedirect.com/science/article/pii/S0160412024004616?via%3Dihub Infektionsradar – Influenza- und Sars-CoV-2-Viruslast im Abwasser: https://infektionsradar.gesund.bund.de/de/influenza/abwasser neues Medizinforschungsgesetz: https://www.recht.bund.de/bgbl/1/2024/324/VO.html elektronische Patientenakte, Bundesministerium für Gesundheit: https://www.bundesgesundheitsministerium.de/themen/digitalisierung/elektronische-patientenakte/epa-fuer-alle.html Finanzmittel-Pakt für den Öffentlichen Gesundheitsdienst: https://www.bundesgesundheitsministerium.de/themen/gesundheitswesen/pakt-fuer-den-oegd.html Gematik – Nationale Agentur für digitale Medizin: https://www.gematik.de/ Podcast-Tipp: Quarks Spezial https://1.ard.de/quarks_daily_spezial_tierversuche_braucht_es_sie