Podcasts about life outcomes

In dieser Folge spreche ich mit Florent Crépin, Geschäftsführer von Neurolite. Er stellt eine Depressions-Behandlung vor, die ohne Medikamente auskommt.Links :LinkedIn Instagram NeuroliteYoutube Instagram FlowFacebook FlowÜBER DEPRESSIONDepressionen.ch Stiftung Deutsche DepressionshilfeREFERENZENBarker et al. Non-invasive magnetic stimulation of human motor cortex. Lancet. 1985 May. Zur PublikationRush et al. Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry. 2006 Nov. Zur PublikationFregni et al. Evidence-Based Guidelines and Secondary Meta-Analysis for the Use of Transcranial Direct Current Stimulation in Neurological and Psychiatric Disorders. Int J Neuropsychopharmacol. 2021 Apr. Zur PublikationWoodham et al. Home-based transcranial direct current stimulation treatment for major depressive disorder: a fully remote phase 2 randomized sham-controlled trial. Nat Med. 2025 Jan. Zur PublikationCipriani et al. Comparative Efficacy and Acceptability of 21 Antidepressant Drugs for the Acute Treatment of Adults With Major Depressive Disorder: A Systematic Review and Network Meta-Analysis. Focus (Am Psychiatr Publ). 2018 Oct. Zur PublikationSaelens et al. Relative effectiveness of antidepressant treatments in treatment-resistant depression: a systematic review and network meta-analysis of randomized controlled trials. Neuropsychopharmacology. 2024 Dec. Zur PublikationGriffiths et al. Self-Administered “Flow” Transcranial Direct Current Stimulation (tDCS) Depression Treatment in a Crisis Resolution & Home Treatment (CRT) Service: Functioning, and Health-Related Quality of Life Outcomes. Open Journal of Psychiatry. 2024 Nov. Zur PublikationTomonaga et al. The economic burden of depression in Switzerland. Pharmacoeconomics. 2013 Mar. Zur PublikationDeutsche S3-Leitlinie und Nationale VersorgungsLeitlinie (NVL)  Kurzfassung – Lass mir Feedback da :)Hat dir die Folge gefallen? Ich würde mich über eine 5-Sterne-Bewertung sehr freuen! :)Webseite: https://www.psychologieunddenn.ch/Whatsapp-Gruppe (offen für alle): https://chat.whatsapp.com/JBcjpAaIaSeCRxmQMQWGXuMöchtest du Werbung schalten oder mit mir zusammenarbeiten. Dann schau hier vorbei.

We welcome Mary-anne Hodd to the podcast to discuss adverse childhood experiences (also known as ACEs). Mary-anne explains how neglect, abuse and household dysfunction in early childhood can have an impact on later-life outcomes for care-experienced people -- and how we can support young people to start to heal. Mary-anne is a care-experienced trainer and consultant with Trauma Informed Consultancy Services who combines her own lived experience with her background in psychology. Listen to this episode to hear how Mary-anne takes a strengths-based approach to ACEs. Hear a new episode of the Creative Life Story Work podcast on the first Thursday of each month.Find out more about Creative Life Story Work membership here, and sign up to our mailing list here, for regular updates on our training and resources.Want to learn more from Mary-anne Hodd?Check out the training we have coming up, with online Live Classrooms by Natalie and other brilliant trainers>>

Read the full transcript here. How much progress has psychology made on the things that matter most to us? What are some psychological findings we feel pretty confident are true? How much consensus is there about the Big 5 personality traits? What are the points of disagreement about the Big 5? Are traits the best way of thinking about personality? How consistent are the Big 5 traits across cultures? How accurately do people self-report their own personality? When are psychophysical measures more or less useful than self-report measures? How much credence should we lend to the concept of cognitive dissonance? What's the next phase of improvement in the social sciences? Has replicability improved among the social sciences in, say, the last decade? What percent of papers in top journals contain fraud? What percent of papers in top journals are likely unreplicable? Is it possible to set the bar for publishing too high? How can universities maintain a high level of quality in their professors and researchers without pressuring them so hard to publish constantly? What is the simpliest valid analysis for a given study?Simine Vazire's research examines whether and how science self-corrects, focusing on psychology. She studies the research methods and practices used in psychology, as well as structural systems in science, such as peer review. She also examines whether we know ourselves, and where our blind spots are in our self-knowledge. She teaches research methods. She is editor-in-chief of Psychological Science (as of 1 Jan, 2024) and co-founder (with Brian Nosek) of the Society for the Improvement of Psychological Science. Learn more about her and her work at simine.com.Further reading:"How Replicable Are Links Between Personality Traits and Consequential Life Outcomes? The Life Outcomes of Personality Replication Project", by Christopher J. Soto"Machine learning uncovers the most robust self-report predictors of relationship quality across 43 longitudinal couples studies", by Joel, Eastwick, Allison, and WolfNote from Spencer: I misremembered this study as trying to predict breakups when actually the variable they found they couldn't predict is change in relationship-quality over time. The authors said that "relationship-quality change (i.e., increases or decreases in relationship quality over the course of a study) was largely unpredictable from any combination of self-report variables". StaffSpencer Greenberg — Host / DirectorJosh Castle — ProducerRyan Kessler — Audio EngineerUri Bram — FactotumWeAmplify — TranscriptionistsMusicBroke for FreeJosh WoodwardLee RosevereQuiet Music for Tiny Robotswowamusiczapsplat.comAffiliatesClearer ThinkingGuidedTrackMind EasePositlyUpLift[Read more]

This recording features audio versions of August 2024 Journal of Vascular and Interventional Radiology (JVIR) abstracts:Safety and Effectiveness of Endovascular Treatment of Complications Associated with Persistent Sciatic Artery: A Qualitative Systematic Review ReadA Qualitative Systematic Review of Endovascular Management of Renal Artery Aneurysms ReadHemorrhagic Adverse Events of Transthoracic Needle Biopsy of the Lung in Patients with Pulmonary Hypertension: A Systematic Review and Meta-Analysis ReadRecurrence of Pulmonary Arteriovenous Malformation after Embolization in Patients with Pulmonary Hypertension ReadClinical, Functional, and Quality-of-Life Outcomes after Computer Assisted Vacuum Thrombectomy for Pulmonary Embolism: Interim Analysis of the STRIKE-PE Study ReadSafety and Effectiveness of Track Cauterization for Lung Cryoablation ReadComparison of Outcomes of Drug-Coated Balloons versus Plain Balloons in Secondary Interventions on Percutaneous Arteriovenous Fistulae ReadTransperineal Laser Ablation of the Prostate for Symptomatic Benign Prostatic Hyperplasia: Long-Term Follow-Up in 40 Patients ReadJVIR and SIR thank all those who helped record this episode:Host:Manbir Singh Sandhu, University of California Riverside School of MedicineAudio editor:Hannah Curtis, Loma Linda University School of MedicineAbstract readers:Vasan Jagadeesh, University of California San Diego School of MedicineDhanush Reddy, MBBS, Massachusetts General HospitalAshwin Mahendra, Florida Atlantic University Charles E. Schmidt College of MedicineTaji Kommineni, MD, JD, LLM, Emory UniversityAnna Hu, George Washington University School of Medicine and Health SciencesBrian Ng, MD, University of California Los AngelesJack Ficke, Frank H. Netter School of MedicineMark Oliinik,  Loma Linda University School of Medicine©  Society of Interventional RadiologySupport the Show.

Investment has outcomes that impact real people. How do we balance sustainable principles with financial returns?Our Guest: Alan Higgins is the ex Chief Investment Officer and current Managing Director of Coutts Wealth Management. Please subscribe to be first to know about new episodes. Our website www.johcm.com The information contained within this podcast including any expression of opinion is for information purposes only and is given on the understanding that it is not a recommendation. Views are as of date of recording and are subject to change. Hosted on Acast. See acast.com/privacy for more information.

reference: Sri Aurobindo and the Mother, The Hidden Forces of Life, Ch. 1 Life Through the Eyes of the Yogin, pp. 7-8 More information about Sri Aurobindo can be found at http://www.aurobindo.net The US editions and links to e-book editions of Sri Aurobindo's writings can be found at http://www.lotuspress.com 

Illness severity scores are commonly used for mortality prediction and risk stratification in pediatric critical care research. However, as mortality has steadily declined in the pediatric intensive care unit there has been increasing attention given to evaluating non-mortality outcomes in survivors. In this episode we meet Early Career Investigator Elizabeth Killien from Seattle Children's Hospital. In order to evaluate the ability of two commonly used illness severity scores to predict morbidity outcomes, she performed a secondary analysis of the Life After Pediatric Sepsis Evaluation (LAPSE) multicenter longitudinal cohort study of functional and health-related quality of life outcomes among survivors of septic shock.Read the full article here: Predicting functional and quality-of-life outcomes following pediatric sepsis: performance of PRISM-III and PELOD-2 | Pediatric Research (nature.com) Hosted on Acast. See acast.com/privacy for more information.

This episode introduces a Swiss research paper titled "Cross-Sectional Validity and Specificity of Comprehensive Measurement in Lower Extremity Lymphedema and Lipedema: A Comparison of Five Outcome Assessment Tools."This peer-reviewed paper was published in the Health Quality and Life Outcomes journal in July 2020. The study's primary goal was to assess the effectiveness of five different assessment instruments in evaluating the outcomes of lymphedema and lipedema treatments.The authors aimed to determine the instruments' validity in measuring various aspects and health dimensions of these conditions while also assessing their ability to differentiate between lymphedema and lipedema.This research is particularly valuable for healthcare providers treating women with lipedema, as it provides insights into reliable assessment tools they can consider for their practice.

Drs Patel, Wright, and Devoe revisit their involvement in the SWOG S1801 trial to highlight available resources that can expand the reach of cancer care in the community oncology setting. Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/989040). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources Malignant Melanoma https://emedicine.medscape.com/article/280245-overview Neoadjuvant-Adjuvant or Adjuvant-Only Pembrolizumab in Advanced Melanoma https://www.nejm.org/doi/full/10.1056/NEJMoa2211437 Event-Free Survival https://www.cancer.gov/publications/dictionaries/cancer-terms/def/event-free-survival National Cancer Institute Community Oncology Research Program (NCORP) https://prevention.cancer.gov/major-programs/nci-community-oncology-research-program-ncorp SWOG Cancer Research Network https://www.swog.org/ ECOG-ACRIN Cancer Research Group https://ecog-acrin.org/ NRG Oncology https://www.nrgoncology.org/ Children's Oncology Group https://childrensoncologygroup.org/ Effectiveness of Adjuvant Pembrolizumab vs High-Dose Interferon or Ipilimumab for Quality-of-Life Outcomes in Patients With Resected Melanoma: A Secondary Analysis of the SWOG S1404 Randomized Clinical Trial https://jamanetwork.com/journals/jamaoncology/article-abstract/2798988 Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma (MelMarT-II) https://clinicaltrials.gov/study/NCT03860883

It's so easy to play the blame game, isn't it? It's nice living in our own little delusional worlds where EVERYONE ELSE is the problem and we don't have any toxic traits, never mess up, and can't possibly be wrong about anything. I hate to be the one to tell you this bucko, but the blame game is actually what's keeping you stuck. Your inability to take accountability for your mistakes, the way you've hurt others, and the role you play in your own suffering might just be the reason why you're so down bad and in the trenches right now. When I learned to finally own my shit and be honest with myself and others about my imperfections, flaws, and failures, my life changed for the better. Today we're talking about how blame leaves us powerless in our own lives and how taking accountability is your one way ticket to getting that power back, baby!!! If you're ready to get unstuck and level up your life, relationships, and overall mental health, you gotta give this epi a listen. Let's gooooooooo!   Resources mentioned in this episode: Brene Brown's video on blame: https://www.youtube.com/watch?v=RZWf2_2L2v8 Julien Blanc (@julienhimself): https://www.instagram.com/julienhimself/   Follow Wrestling With Life: https://linktr.ee/wrestlingwithlife  

"Whether it was easier or harder, whatever, whether children were fussing with us or happy with us as parents, it was the philosophy and the theology and the desire to be together as a family that really drove us." – Dr. Brian Ray Yvette Hampton engages in a thought-provoking conversation with Dr. Brian Ray, an esteemed authority on homeschooling research. Explore the Bible's teachings on education and the vital role of parents as primary educators. Discover Dr. Ray's groundbreaking study, which provides compelling evidence on the academic success and overall positive outcomes of homeschooling. Challenge prevailing misconceptions and stereotypes about homeschooling as we unpack the advantages of parent-directed home-based education discipleship. Gain valuable insights on how homeschooling fosters a nurturing environment, enhances engagement, and promotes holistic well-being. Don't miss this empowering episode on the Schoolhouse Rocked Podcast! Watch this full conversation on our YouTube channel. Dr. Brian Ray is a leading international expert in research on homeschooling and president of the National Home Education Research Institute (NHERI). He has published numerous articles and books, is interviewed by major media, serves as an expert witness in court cases, and testifies to legislatures regarding education. He is a former university professor and public and private school classroom teacher. He holds a Ph.D. (science education, Oregon State University), a M.S. (zoology, Ohio University), and a B.S. (biology, University of Puget Sound), and is a church leader. Brian and Betsy have been married 44 years, have eight children who were all home educated, run a small farm, and have 19 grandchildren. Dr. Ray really enjoys wandering with Betsy, his wife, and being out in the forests and mountains and on adventures. See research at www.nheri.org. Discussion Questions: How does Dr. Brian Ray's research challenge the perception that homeschooling is inferior to traditional schooling? What are some key factors that contribute to the academic success of homeschooled children, according to Dr. Ray's research? How does Dr. Ray address concerns about child abuse and neglect in homeschooling families, and what data does he present to support his arguments? How does Dr. Ray's personal background and experiences influence his perspective on homeschooling? What are some potential drawbacks or challenges of homeschooling that Dr. Ray acknowledges, and how does he address them? How has the acceptance and perception of homeschooling changed over the years, according to Dr. Ray? How does homeschooling impact the overall well-being and mental health of children, as discussed by Dr. Ray? How does Dr. Ray argue that homeschooling can contribute to the improvement of local communities and nations? What are some practical strategies and suggestions for parents to prioritize their children's well-being in the midst of societal and technological challenges, according to Dr. Ray? In your opinion, based on the information presented by Dr. Ray, what are the major advantages and disadvantages of homeschooling compared to traditional schooling? Recommended Resources:  Podcast Note-Taking Guide The Gen2 Survey, by NHERI (National Home Education Research Institute) - This study examines adults who attended church growing up and seeks to understand the key influences which either encouraged or deterred them from believing and practicing the faith of their parents. Answers for Homeschooling: Top 25 Questions Critics Ask, by Israel Wayne Education: Does God Have an Opinion?, by Israel Wayne Israel Wayne, Christian Education: A Manifesto  Education: The Key to Saving Our Nation – Alex Newman on the Schoolhouse Rocked Podcast Getting Started in Homeschooling - Israel Wayne on the Schoolhouse Rocked Podcast    It's not too late to enjoy the Homegrown Generation Family Expo - now at a new, lower price! Register today for lifetime access to every session - and BONUS access to the 2020 conference. Use the coupon code PODCAST to save 25% when you register today. Register at HomegrownGeneration.com.   Support Schoolhouse Rocked! Has the Schoolhouse Rocked Podcast been a blessing to you? Support from our listeners allows us provide resources, support, and encouragement to homeschooling families around the world. Please consider donating to support Schoolhouse Rocked.   Be the most popular mom in your co-op. Get your Schoolhouse Rocked merch here. SPONSORS: CTCMath - CTCMath specializes in providing online video tutorials that take a multi-sensory approach to learning. Creative graphics and animation, synchronized with the friendly voice of internationally acclaimed teacher, Pat Murray, make learning math easy and effective. Start your free trial today. BJU Press Homeschool provides complete curriculum for preschool through 12th grade with both traditional textbooks and video courses available. Education from a Christian worldview reshapes how children see the world. BJU Press materials teach Christ's power and lordship through the Big Story of creation. The Institute for Excellence in Writing (IEW) equips teachers and teaching parents with methods and materials which will aid them in training their students to become confident and competent communicators and thinkers. Using the Structure and Style™ writing method, IEW will give you the ability to fill young minds with language-building skills, laying the groundwork for a lifetime of excellent writing. Apologia – Apologia is a Christ-centered, award-winning homeschool curriculum provider. Our mission is to help homeschooling students and families learn, live, and defend the Christian faith through our print and digital curriculum and online classes. The Schoolhouse Rocked Podcast is proud to be a member of the Christian Podcast Community.   Connect with us: @schoolhouse_rocked on Instagram Schoolhouse Rocked on Facebook Schoolhouse Rocked on YouTube @SRHomeschool on Twitter Schoolhouse Rocked Website (Blog, Newsletter, Support, Store, Movie, and More!)

"Whether it was easier or harder, whatever, whether children were fussing with us or happy with us as parents, it was the philosophy and the theology and the desire to be together as a family that really drove us." – Dr. Brian Ray Yvette Hampton eng...

Founder and President of the National Birth Equity Collaborative, Dr. Joia Crear-Perry joins us to discuss race, maternal health, healthcare and life outcomes. Dr. Crear-Perry is a physician, policy expert, thought leader, and advocate for transformational justice who identifies and challenges racism as a root cause of health inequities. She is a highly sought-after trainer and speaker who has been featured in national and international publications, including Essence and Ms. magazines. She has twice addressed the Office of the United Nations High Commissioner for Human Rights to urge a human rights framework to improve maternal mortality. Previously, she served as the Executive Director of the Birthing Project USA, Director of Women's and Children's Services at Jefferson Community Health Care Centers, and Director of Clinical Services for the New Orleans Health Department. A proud recipient of the Congressional Black Caucus Healthcare Heroes award, she currently serves on the Board of Trustees for Community Catalyst, the National Medical Association, and the New Orleans African American Museum. Dr. Crear-Perry completed her medical degree at Louisiana State University and her residency in obstetrics and gynecology at the Tulane University School of Medicine. She was also recognized as a Fellow of the American College of Obstetricians and Gynecologists.

Listen in as we explore how the attitudes and life philosophies of those around us can shape our behaviour, attitudes, and outcomes, emphasizing the importance of being intentional with the company we keep. Turn this episode up loud and learn how surrounding yourself with the right people can make all the difference in achieving what you want in your practice.--- 

Thank you for joining us for this episode of OnlyPods number 35. In this wisdom broadcast we had fun and hope you do too, just expect nothing and enjoy the surprises. Listen on live when we record Friday evenings in the following three apps: YouTube Account: https://www.youtube.com/channel/UC-FdGPdpohuIGrk-PGKNi4g Twitch Account: https://www.twitch.tv/pref_n_ref_podcast The Wisdom App on iOS and Android: https://joinwisdom.audio/pref_ref Other ways to stay in touch: Linktr.ee: https://linktr.ee/Pref_Ref_Podcast Listen to us wherever you listen to podcast: https://anchor.fm/prefs-refs-podcast Welcome to our discussion based Podcast, where we talk about a wide range of ever changing topics that match our guests and Co-hosts. We are doing this as a labor of love always remembering to accept a different viewpoint to ours. If you have ideas, topics, comments and or thoughts please reach out to our email Pref.Refpodcast@gmail.com. We have lots of things planned for you all please stay tuned for more. Outro credits to: "Tokyo Music Walker - Way Home" is under a Creative Commons (cc-by) license Music promoted by BreakingCopyright: https://bit.ly/tokyo-walker-way-home T.Nakata

Jacinta and Lachlan speak to Orion Kelly about all things autism as he shares his diagnosis journey and lived experience.    About our guest Orion Kelly is proudly Autistic. He is an Autistic advocate, consultant, keynote speaker, author, actor, host, YouTuber, podcaster and radio broadcaster based in Victoria, Australia. Orion hosts the podcasts My Friend Autism, A Different Brilliant, and Intensely Inquisitive. Plus, he has his own Autistic focused YouTube channel.   Content warning In this episode of Differently Brained we discuss anxiety, depression and suicidality. Please feel free to skip this episode or reach out to medical professionals if it has brought anything up for you.   Resources & representations Orion's YouTube channel My Friend Autism A Different Brilliant Intensely Inquisitive Oodies Theraputty Suits The Services, Support and Life Outcomes for Autistic Australians government report the Amaze website, specifically this article on talking about autism in media.    About the podcast Differently Brained shares the opinions of individuals and does not consider your personal circumstances. Differently Brained exists purely for information purposes and should not be relied on as health or medical advice. Because no brain is the same, please consult your healthcare professional for your personal medical needs. The Differently Brained team acknowledge the traditional custodians of the lands on which we record, edit and stream this podcast. We pay our respects to all First Nations peoples and their Elders part, present and emerging. We extend that respect to all First Nations cultures and their ongoing connection to the lands, waterways and communities.

Editor-in-Chief Dr. Sue Yom hosts Dr. Shankar Siva, Associate Professor and Radiation Oncologist from the Peter MacCallum Cancer Centre, Australia and the supervising author of "Cost-Effectiveness of Single- versus Multi-Fraction SABR for Pulmonary Oligometastases - The SAFRON II Trial"; Dr. David Sher, Professor at the University of Texas Southwestern Medical Center and the Red Journal's Methodology Section Editor who first-authored this month's OncoScan "The Cost-Effectiveness of Consolidative Radiation Therapy in Oligometastatic Disease: High-Value Proposition or Wishful Thinking?"; and Dr. Aisling Barry, Professor and Chair of Radiation Oncology at University College Cork and Cork University Hospital, Ireland, who first-authored "The Impact of Disease Progression on Health-Related Quality of Life Outcomes in Patients with Oligo-Metastatic Disease at 12-Months post Stereotactic Body Radiotherapy."

What picture do you have framed on your desk to help remind you not to make assumptions about patients? Listen as Dr. Ted McRackan talks real-life outcomes of patients with CI, and dives headfirst into the Cochlear Implant Quality of Life Profile (CIQOL) framework. He relays challenges in connecting test results with a patient's perceived real-world function, and shares insight into how providers can use this type of data during discussions of expectations with potential CI users and throughout a CI patient's care. Ted R. McRackan, M.D., is the director of the Skull Base Center in the Department of Otolaryngology – Head and Neck Surgery at MUSC. Stay up to date with us on LinkedIn, Facebook, Twitter and Instagram @MedAudPro. Joining the MedAudPro Provider Community is a great way to support our show, get free access to behind the password content and interact with other providers looking to practice at the top of their game. Subscribe today at bit.ly/JoinMedAudPro This episode is sponsored by Envoy Medical.

The Journal of Rheumatology's Editor-in-Chief Earl Silverman discusses this month's selection of articles that are most relevant to the clinical rheumatologist. Included is an excerpt from this month's Editor's Picks spotlight interview with authors Bente Glintborg, Dorte Vendelbo Jensen, Lene Terslev, Oliver Hendricks, Mikkel Østergaard, Simon Horskjær Rasmussen, Mogens Pfeiffer Jensen, Thomas Adelsten, Ada Colic, Kamilla Danebod, Malene Kildemand, Anne Gitte Loft, Heidi Lausten Munk, Jens Kristian Pedersen, René Drage Østgård, Christian Møller Sørensen, Niels Steen Krogh, Jette Nørgaard Agerbo, Connie Ziegler and Merete Lund Hetland about their article "Long-term Behavioral Changes During the COVID-19 Pandemic and Impact of Vaccination in Patients With Inflammatory Rheumatic Diseases" - doi.org/10.3899/jrheum.211280 This month's selections also include: Canadian Rheumatology Association Living Guidelines for the Pharmacological Management of Rheumatoid Arthritis With Disease-Modifying Antirheumatic Drugs - doi.org/10.3899/jrheum.220209 From Canadian Living Guidelines to Global Living Guidelines: A Post Pandemic Effort - doi.org/10.3899/jrheum.220811 Simplified Ankylosing Spondylitis Disease Activity Score (SASDAS) Versus ASDAS: A Post Hoc Analysis of a Randomized Controlled Trial - doi.org/10.3899/jrheum.211075 Is It Good to Simplify Clinimetry in Chronic Inflammatory Joint Diseases? - doi.org/10.3899/jrheum.220543 A Practical Guide for Assessment of Skin Burden in Patients With Psoriatic Arthritis - doi.org/10.3899/jrheum.210550 Personally Generated Quality of Life Outcomes in Adults With Juvenile Idiopathic Arthritis - doi.org/10.3899/jrheum.211245 Giant Geode at the Humeral Head in the Rheumatoid Shoulder Treated With Allograft Bone Grafting and Shoulder Arthroplasty - doi.org/10.3899/jrheum.211082 To read these, and other full articles visit www.jrheum.org. Music by David Hilowitz

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A research paper links under-performance in reading and maths among 15-year-olds with worse outcomes later in life. The paper shows that those with low literacy and numeracy skills in their teens are likely to have lower earnings and higher rates of hospitalisation than more skilled students. New Zealand Work Research Insitute director Gail Pacheco spoke to Guyon Espiner.

Drs Sumanta Pal and Brian Rini discuss front-line treatment of renal cell carcinoma. Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/968736). The topics and discussions are planned, produced, and reviewed independently of advertiser. This podcast is intended only for US healthcare professionals. Resources Bevacizumab Plus Interferon-alpha Versus Interferon-alpha Monotherapy in Patients With Metastatic Renal Cell Carcinoma: Results of Overall Survival for CALGB 90206 https://ascopubs.org/doi/10.1200/jco.2009.27.18_suppl.lba5019 An updated table of the front-line IO combination RCC studies that have shown an OS advantage https://twitter.com/brian_rini/status/1309609380585844736/photo/1 Targeting PD-1 or PD-L1 in Metastatic Kidney Cancer: Combination Therapy in the First-Line Setting https://aacrjournals.org/clincancerres/article/26/9/2087/83102/Targeting-PD-1-or-PD-L1-in-Metastatic-Kidney Conditional Survival and Long-term Efficacy With Nivolumab Plus Ipilimumab Versus Sunitinib in Patients With Advanced Renal Cell Carcinoma https://acsjournals.onlinelibrary.wiley.com/doi/10.1002/cncr.34180 International Metastatic Renal Cell Carcinoma Database Consortium Criteria https://www.uptodate.com/contents/image?imageKey=ONC%2F116130&topicKey=ONC%2F2984&source=see_link Molecular Correlates Differentiate Response to Atezolizumab (atezo) + Bevacizumab (bev) vs Sunitinib (sun): Results From a Phase III Study (IMmotion151) in Untreated Metastatic Renal Cell Carcinoma (mRCC) https://cslide.ctimeetingtech.com/esmo2018/attendee/confcal/presentation/list?q=LBA31 Nivolumab Versus Everolimus in Patients With Advanced Renal Cell Carcinoma: Updated Results With Long-term Follow-up of the Randomized, Open-Label, Phase 3 CheckMate 025 Trial https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415096/pdf/nihms-1732721.pdf Lenvatinib Plus Pembrolizumab or Everolimus for Advanced Renal Cell Carcinoma https://www.nejm.org/doi/10.1056/NEJMoa2035716 The Uromigos Debate: Treatment of Favorable Risk Renal Cancer https://anchor.fm/the-uromigos/episodes/Episode-67-The-Third-Uromigos-Debate---fPD1VEGF-vs-PD1CTLA4-for-front-line-renal-cancer-emjpji Health-Related Quality-of-Life Outcomes in Patients With Advanced Renal Cell Carcinoma Treated With Lenvatinib Plus Pembrolizumab or Everolimus Versus Sunitinib (CLEAR): A Randomised, Phase 3 Study https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(22)00212-1/fulltext Study of Cabozantinib in Combination With Nivolumab and Ipilimumab in Patients With Previously Untreated Advanced or Metastatic Renal Cell Carcinoma (COSMIC-313) https://clinicaltrials.gov/ct2/show/NCT03937219 A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012) https://clinicaltrials.gov/ct2/show/NCT04736706 Twitter poll questions: What magnitude of benefit is required to adopt triplets? OS https://mobile.twitter.com/brian_rini/status/1508450496104783877 What magnitude of absolute PFS benefit vs doublets is required to adopt triplets? https://mobile.twitter.com/brian_rini/status/1508450910506295305 What would be the most convincing endpoint to adopt triplets? https://mobile.twitter.com/brian_rini/status/1508451622564909057 Molecular Subsets in Renal Cancer Determine Outcome to Checkpoint and Angiogenesis Blockade https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436590/ OPtimal Treatment by Invoking biologic Clusters in Renal Cell Carcinoma (OPTIC RCC) https://www.kcameetings.org/wp-content/uploads/2021/12/IKCSNA21_TIP8_Chen.pdf

Eddie was not in the popular crowd. As far as he knew he was not in the popular universe. Everyone else at this party seemed not only taller than him, they were also drunker than him. About the time things seemed to be getting weirder, he'd decided to leave. Eddie heard a shout from across the room,“Little Eddie! Where are you going?” Eddie turned just in time to see Ken approaching quickly to head him off. Eddie stopped in his tracks. After Ken had made the football team, and Eddie hadn't, Ken had stopped being any kind of friend, and had made fun of Eddie's wrestling just about every time they met. Even after Eddie had won his weight class at State, it was always the same insults about wresting around with a bunch of sweaty guys on a sweaty mat. Eddie RESPONDED, “Just headed home. Got early church tomorrow man.” Ken's slurred speech gave his drunkenness away, “You can pray tomorrow, but you ain't going nowhere tonight.” Eddie RESPONDED, “Sorry to disappoint you. Gotta go.” Just then Ken launched himself at Eddie's midsection in a full tackle. Eddie RESPONDED immediately by dropping into a standing sprawl, controlling any tackle from occurring by keeping Ken's hands and arms at bay. However Ken was bigger and continued to push. Eddie knew he's have to move Ken around and control his ability to push him over. Eddie dropped his head and pushed the hard part of his skull as if he had horns into Ken's eye socket, temple and nose. “Ouch!” Ken said, and released rubbing his bloody nose and blackening eye. Dropping his hands to his knees and breathing hard. Ken spat out.“We'll go then you little…!” Eddie tapped Ken on the shoulder, “Sleep it off my friend. I'll tell Reverend Mike you said, hey.” Ken went home soon after, and did sleep it off. Eddie called to see how he was doing after church the next day, and Ken apologized. From that day they were back to being friends. Eddie thought many times over their lifetime about that night, and how grateful he was for his RESPONSE. Both Ken and Eddie never made college teams, however, their years of friendship were long, and their children's children grew up like family together for holidays, blessings, baptisms and weddings. Eddie's RESPONSE in self-defense changed his life forever. Eddie could have easily taken Ken out, however, he didn't. We all have the ability to create our world in each RESPONSE we have each and every day. Remember it's not what happens to us that makes the difference, it's how we RESPOND that creates our future. Life is full of conflict. In fact everything in life has an element of conflict. How will you RESPOND? Because how you RESPOND is what you will create in your next conflict, and life. RESPOND… Allen Hughes Life Defense Coach #lifedefense #respond #allenhughes --- Send in a voice message: https://anchor.fm/allen-hughes/message

Brenden Kumarasamy is a communications expert and the founder of MasterTalk, how to become a master communicator. Where one may at first consider what he does only applicable to corporate environments and high-dollar situations, all one need do is think about the chaos of our daily lives as individuals trying to thrive in our social settings and we realize that the power of better communication applies to all of us, at all levels. He teaches us how to overcome our fears, and just talk to each other, truly talk to each other, which as so many of us often forget requires that we truly listen to each other. Listen in as we Etch The Edges with Brenden and learn how he came upon this field and became such an expert. How he honed his skill into helping others. And now, why he is taking the time to make sure the gifts he provides can be utilized by anyone, not just big business. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/etchtheedges/support

A 10-year study out of UCSF finds that 95% of people report that having an abortion was the right decision for them. KCSB's Ashley Rusch speaks to Dr. Diana Greene Foster, Professor at UCSF and lead researcher of the Turnaway Study.

In this episode of the Award-winning PRS Journal Club Podcast, 2022 Resident Ambassadors to the PRS Editorial Board – Saïd Azoury, Emily Long, and Ronnie Shammas- and special guest Vu T. Nguyen, MD, discuss the following articles from the April 2022 issue: “Prepectoral and Subpectoral Tissue Expander– Based Breast Reconstruction: A Propensity- Matched Analysis of 90-Day Clinical and Health-Related Quality-of-Life Outcomes” by Nelson, Shamsunder, Vorstenbosch, et al. Read the article for FREE: https://bit.ly/TissueExpanderOutcomes Special guest Vu T. Nguyen, MD is an Associate Professor of Plastic Surgery at the University of Pittsburgh and Program Director of the Pittsburgh Plastic Surgery Residency. Dr. Nguyen completed his residency training at the University of Pittsburgh followed by a Microsurgery Fellowship at the University of Pennsylvania. READ the articles discussed in this podcast as well as free related content from the archives: https://bit.ly/PRSApril22Collection 

In Episode 2 of Series 4 of the DIAL Podcast, we are in discussion with Professor Hans van Kippersluis from the Erasmus University in Rotterdam. Hans, a professor of applied economics, is the Principal Investigator on the DIAL project, Gene Environment Interplay in the Generation of Health and Education Inequalities, which has used innovative methods and data to explore the interplay between nature and nurture in generating health and education inequalities.   Transcript Christine Garrington  0:00   Welcome to DIAL, a podcast where we tune in to evidence on inequality over the life course. In series four, we're looking at what's been learned from some of the DIAL projects about how and when inequality manifests in our lives, and what its longer term consequences might be. For this second episode of the series, we're delighted to be joined by Hans van Kippersluis, Professor of Applied Economics at the Erasmus University in Rotterdam. And Principal Investigator of the DIAL project, Gene Environment Interplay in the Generation of Health and Education Inequalities - put more simply nature versus nurture. So Hans, welcome to the podcast. And I wonder if you can start by talking us through what researchers working on this project have actually been looking into. Hans van Kippersluis  0:42   What we've been doing in this project is essentially incorporating the recent availability of genetic data into social science and most prominently economic analysis. And so most of our work has focused on the interplay between genes and the environment. So in the introduction, you mentioned nature versus nurture, but actually more accurately, what we're doing is nature and nurture jointly into how they shape essentially education and health outcomes. And I think this is also the main innovation of our project, because biologists have studied nature before; social scientists have  of course, extensively studied nurture, but not many have studied the interplay, the interaction between the two. And I think this was sort of the main innovation for why we got the funding some five years ago. And so what we have done is mostly studying this interplay. But along the way, we have also made some methodological contributions to a field which is very new. Then we've also used genetic data to test all their theories, and also, I think, enrich the framework of equality of opportunity. Christine Garrington  1:35   Yeah, fantastic project. And as you've just said, you've made unprecedented use of genomic as well as survey data in the research, tell us a bit more about the information that you've been able to access? And how you've been able to use it? Hans van Kippersluis 1:47   Yeah, sure. So the interesting thing is that more and more social science datasets, so data sets that have been traditionally used by social scientists, and these are mostly extensive surveys,  are now collecting DNA information from their respondents. And this is often from blood or saliva. And what they did is basically, so more than 99% of DNA is the same across human beings. And so what we are using is only this remaining less than 1% of the variation. And these are called snips. And snips are points of your DNA that differ across human beings. And there's roughly 1 million of them. And so what we do, basically also other people have done is sort of aggregating these tiny effect sizes into an index. And this is called the polygenic index. And this is telling us something about your genetic predisposition towards a certain outcome. And this is quite interesting, because this data, this new variable, essentially can be added to existing datasets. And so we have a wealth of information that has been collected in the past on surveys on existing data. And then we simply add one indicator, one new variable. This is telling us something about people's genetic predisposition. And just to be clear, this is not like a deterministic variable. It also exhibits quite a bit of measurement error and noise. But at the group level, and that's what we have been doing is it sort of does tell us something about your genetic predisposition, and it can help us understand how certain life outcomes like education, like health, are shaped by the interplay between your genetic predisposition and your environment. Christine Garrington  3:07   Indeed, let's talk a little bit now then about some of the research findings. And you know, what's come out of this now, one piece of research we've spoken about this actually, in an earlier podcast episode, actually drew links between mothers smoking in pregnancy and their baby's birth weight. I wonder if you can just sort of summarise that for you what actually came out of that what we learned Hans van Kippersluis 3:28   this was work with with my PG students, Rita Dias Pereira and colleague Cornelius Rietveld. And for birthweight we knew that maternal smoking is one of the key environmental risk factors. And we also knew from genetic studies that genes matter in determining your birth weight. And so what we did here was essentially looking at the interaction between the two. So can higher polygenic indices protect against maternal smoking? And the answer, unfortunately, perhaps was no, in the sense that we found very, very little interaction between genes and the environmental exposure of maternal smoking. So it seems that both matter, but there doesn't seem to be any meaningful interaction between the two. So that was, to some extent surprising, but on the other hand, also perhaps logical in the sense that maternal smoking is apparently such a devastating environmental exposure that even higher genetic predisposition cannot protect you from this. Christine Garrington  4:16   Yeah, really interesting. And anybody who's interested in that can listen to Rita actually discussing that in series three, Episode Seven, of our DIAL podcast called Mums Who Smoke and their Baby's Birthweight. So do check that out if you're interested to know a little bit more about what Rita and all of the all of your colleagues did. Now, there have been some interesting findings Hans from the project around the role of genes in a child's education and specifically around parental investments. I wonder if you can explain a bit more about what you were looking to understand there.  Hans van Kippersluis 4:50   Yes, yeah, so this is one of my favourites studies. It's joint work. Also with another PG student   Muslimova and my colleagues Stephanie von Hinke, Cornelius Rietveld and Fleur Maddens. And the starting point there was actually a theory of human capital formation from economics. And it dates back all the way to the work of Nobel laureate Gary Becker. And one of the crucial assumptions in that model is that parental investments are complementary to your genetic endowments. And this assumption is actually very hard to test because often we do not have a good measure of endowments. And if we do, it may already be contaminated by parental investment. So many people, for example, use birth weights. But of course, well as we just learned, maternal smoking may have a large effect on your birth weight, so it's not fully free of your parents' behaviour. And the other thing is that your parental investments often respond to endowments. So if you have a child with specific needs, of course, parents respond to this. So the problem of testing this assumption is that endowments and investments are actually always very closely entangled. And that makes it very hard to test whether they are complementary or not. So what we did here was using one's genetic endowment, and that is actually has a very nice property and that it's fixed at conception, so it cannot be affected by your parental investments. And what we did was using the child's birth order to proxy for parental investments. So what we know from earlier studies is that firstborns tend to get more parental attentions on average than later points. So this is one after all, because they have undivided attention until the arrival of later borns. And this extra parental investment is actually independent of your endowments. It simply derives from the fact that you have more time if you have one child as opposed to multiple children. So what we did in this study is looking within families comparing siblings that were first born to later borns, and then further analysing whether this firstborn advantage was stronger for firstborn siblings who randomly inherited the higher polygenic index for educatio. I think this was a nice, very unique setting to test this theoretical assumption that parental investments are complements to genetic endowment. Christine Garrington  6:45   What did you find here? Then what do we learn about the role of genetics in affording in affording certain children advantages later on in life? Hans van Kippersluis 6:53   So what we found was that indeed, the firstborn effect seems to be stronger for siblings who randomly inherited higher polygenic indices. And I think this is evidence in favour of this theoretical assumption of complementarity between endowments and investments. And it also means that your genetic predisposition cannot just give you a direct advantage. But it also means that this advantage may be kind of amplified by your parental or your teacher investments. And this complementarity, I think also suggests once again, that for disadvantaged children, so the other side of the coin, we need to start very, very early and follow up these early investments also with data investments to make them as productive as possible. Christine Garrington  7:29   So Hans, some fascinating research and findings. I wonder if there's been a standout or surprising finding for you from the project.  Hans van Kippersluis 7:36   I  think methodologically, what we've learned is that there's still a world to explore in terms of using genetic data in social science, because what we have seen is that polygenic indices can be a great tool to improve our understanding of the things we just talked about. But I think the way we use these polygenic indices, are shall I put this sort of a bit naive, in some sense, because what we do is we first construct a score or an index by regressing an outcome on all of these 1 million individual genetic variants. And as you can imagine, if you do these 1 million regressions, then it will be a lot of noise in  these coefficients, and these estimates also come with some uncertainty. And what is surprising to me, what I've learned is that many researchers simply sort of seek to use this polygenic index as if it's some kind of a transferable and deterministic index. And there's hardly any account in the literature on the uncertainty in this index. And I think what we have done in one paper is actually showing how this uncertainty is sort of leading to different conclusions, because what we did is basically looking at the polygenic index for cardiovascular disease. And in cardiovascular disease, more and more people are using these polygenic indices, this genetic data for personalised decisions regarding, for example, the use of statins. And what we did was sort of constructing six different polygenic indices using different discovery sample using different methods of constructing this polygenic index. And what was fascinating and actually maybe astonishing to see is that only 6% of the individuals are in the top quintile of the polygenic indices, if you look across these six different ways of constructing the same polygenic index. And I think this is fascinating, because it shows that even though polygenic indices are now increasingly being used, apparently it matters a great deal about how you construct these things. And this is one thing we have shown, I think this is quite remarkable, and also an important methodological contribution. Christine Garrington  9:19   A really important contribution to how this research might develop in the future. Right, absolutely. And then just finally, Hans, I wonder what this all of this work tells us about the interplay between genes in our environment, or, as we've talked about nature and nurture, not nature versus nurture, in better understanding and in tackling inequality. Hans van Kippersluis 9:41   So it's very hard, I think, to give sort of direct policy leads or implications, but there's a few leads. One thing is that I think we need to start early. We knew already that inequalities arise early in life. And I think this focus on genetics gives us yet another clue that it's very important to start early. And also because of the work I mentioned about complementarities, it's very clear that later investments are more effective if the person has had already more investments early in their life. So that's clearly one more general policy implication, I think. And I think our work is also showing how sort of genes and environment shaping jointly inequalities. And I think this has important implications for the discussions about equality of opportunity. I mean, if you look at politicians across the entire political spectrum, everybody seems to be agreeing that equality of opportunity is a great thing, and that your health and your income should not depend on your parental background. But let me ask two questions about this. One is, what about your genes? There's hardly any discussion about whether inequalities that are deriving from genetic advantages or disadvantages are fair or not. And what we've also shown in this project is that parental background seems to reinforce genetic advantages. So even if you believe that parental background should not be leading to inequalities and your genes may, then how do you treat the interaction between the two? So I think we should have a clear discussion here a societal discussion about what is fair here. And I think that's why our research is very important, because 30 years studies have already shown that people's preferences for redistribution, for example, depends strongly on whether they perceive inequalities as fair or unfair. So I don't think we are political activists here. But I do think that showing how genes and the environment jointly shape outcomes such as health, education, income, but really help people to make up their own mind as to what they regard as fair or unfair inequalities. Christine Garrington  11:23   Hans thank you very much some some big advances here. But still some big questions to answer, I guess is the is the summary but fascinating work and thank you for taking time to share it with us. So finally, thanks to Hans van Kippersluis  for discussing the findings and implications of DIAL dial project Gene Environment Interplay in the Generation of Health and Education Inequalities. You can find out more about this and other dial research on the website at www.dynamicsofinequality.org. We hope you enjoyed this episode, which is produced and presented by me Chris Garrington of Research Podcasts. And don't forget to subscribe wherever you find your podcasts to access earlier and forthcoming episodes.    

This relationship is more important than any other relationship we will ever have. It also impacts all the other relationships in our lives. Our relationship with ourselves determines how bold, courageous, what kind of risks we take and how we treat other humans. This is the MOST important work we can ever do in our lives. Take some time, really evaluate what kind of friend you are to yourself. Are you trustworthy to yourself? Do you do what you say you are going to do for you? Do you honor your wants? Do you honor your needs? Do you show respect toward yourself? We are blinded by our own beliefs and decades' worth of programming. This work requires self-awareness and it can be extremely helpful to have a non-biased person help make your beliefs about you more obvious so you can then decide. If you are wanting to take this work deeper, apply it and make real changes our New Beginnings Program is there to guide you along the way. We hack your brain to get to these root beliefs and naturally support your body to produce balanced neurochemicals to give the brain the needed ingredients to help you feel better, think more clearly, and make your emotions manageable allowing you to take control of your life and create the results you want. Click on the link for more info: https://www.kimberlyjarmancoaching.com

Jennifer O'Donoghue, fellow in the Center for Universal Education and coordinator of the Echidna Global Scholars program at Brookings, talks with the 2021 scholars—the tenth class of Echidna Scholars—about their research on improving learning opportunities and life outcomes for girls and women across the global south. Show notes and transcript:   Follow Brookings podcasts on Apple, Google podcasts, or Spotify. Send feedback email to , and follow us and tweet us at  on Twitter. The Brookings Cafeteria is part of the .

Health, Wealth, Love, Family, Passion and Vision. How do you build a harmonious, integrated life that leverages the strength from one area to the other?

Hello and welcome to this weeks episode of Macabre for mortals. As you can hopefully hear I am feeling so much better this week and I have finally got my voice back and I feel almost back to normal. This week I am going to be concluding my episode on post traumatic stress disorder and I am going to focus of victims who experience the disorder and the research that has been carried out into this. Just a reminder that June is Post Traumatic Disorder's focus month, I know myself I will be making myself more aware of the community and also donating to the causes in order to help the people suffering. I hope this series will have given you the insight into the disorder and might give you some ideas or tools to help yourself or those you love. My sources this week : McFarlane, A. C., & Papay, P. (1992). Multiple diagnoses in posttraumatic stress disorder in the victims of a natural disaster. Journal of Nervous and Mental Disease, 180(8), 498–504. https://doi.org/10.1097/00005053-199208000-00004 Learning and Memory in Rape Victims With Posttraumatic Stress Disorder Melissa A. Jenkins 1998 https://ajp.psychiatryonline.org/doi/full/10.1176/ajp.155.2.278 The predictive value of post-traumatic stress disorder symptoms for quality of life: a longitudinal study of physically injured victims of non-domestic violence Venke A Johansen, Astrid K Wahl, Dag Erik Eilertsen, Lars Weisaeth & Berit R Hanestad Health and Quality of Life Outcomes volume 5, Article number: 26 (2007) https://hqlo.biomedcentral.com/articles/10.1186/1477-7525-5-26 Thank you for listening to another episode of Macabre for Mortals. If you have any feedback or want me to cover something specific, please drop me and email at macabreformortals@gmail.com. Or send me a DM on Instagram @MacabreforMortals. I hope you have a fantastic week Bye

A common view today is that when we are born, we are somehow born on even footing when it comes to the effects of how we are raised and what this means for us developmentally. We believe this despite the emergence of epigenetic theories that tell us otherwise, but the problem becomes how to actually study this given the myriad variables that are at play. This week I had the pleasure of talking to a leader in this field - Dr. Amanda Dettmer - and her work studying rhesus macaques to explore this very issue of not only intergenerational effects, but how our early life experiences impact so many facets of our lives. We also got talking about anti-animal research perspectives if that's something you're interested in. I hope you'll enjoy this conversation as much as I enjoyed having it. Dr. Dettmer: https://medicine.yale.edu/profile/amanda_dettmer/ Dr. Dettmer on Twitter: https://twitter.com/amanda_dettmer Relevant Articles: https://www.nber.org/papers/w27737 https://onlinelibrary.wiley.com/doi/abs/10.1002/ajp.22969 https://onlinelibrary.wiley.com/doi/abs/10.1002/dev.21916 https://www.tandfonline.com/doi/abs/10.1080/17470919.2016.1176952 https://academic.oup.com/ilarjournal/article/55/2/361/645985 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196800/ To learn more about the Evolutionary Parenting Podcast visit https://evolutionaryparenting.com/evolutionary-parenting-podcast-2/

The cross-over episode is an American tradition that is near and dear to my heart. My childhood is filled with special moments that brought some of my very favorite characters together. Alf crossed over with Gilligan's Island. The Fresh Prince of Bel Air crossed over with The Jeffersons. Mork and Mindy crossed with Happy Days and Laverne and Shirley at the same time. To honor this wonderful tradition, GeriPal is crossing over with the Surgical Palliative Care Podcast for this weeks podcast! The Surgical Palliative Care Podcast is hosted by Dr. Melissa "Red" Hoffman. Red is both an acute care surgeon and hospice and palliative medicine physician in North Carolina. She has been podcasting since this beginning of this year and my goodness she has been quite busy in doing so. Her podcast featured some of the founders and the leaders of the surgical palliative care community, including Dr. Balfour Mount (the father of Palliative Care in North America), Robert Milch, Zara Cooper, and Diane Meier. That's an amazing lineup. We also welcome Joe Lin as a co-host for this topic. Joe is a surgery resident and palliative care fellow at UCSF. We talk to both Joe and Red about - How they got interested in the intersection of surgery and palliative care - How the culture of surgery and palliative care differ (and the misconceptions that both fields have of each other) - What the day in the life of a surgical palliative care physician looks like - A recent article in JAMA Surgery titled "Palliative Care and End-of-Life Outcomes following High-Risk Surgery" - What palliative care skills all surgeons should have (primary palliative care) - And lots of other topics! So take a listen and check out Red's Surgical Palliative Care Podcast (https://thesurgicalpalliativecarepodcast.buzzsprout.com/)

You have to see it - and hear it - to believe it! David Goodwin, our special guest and President of the Association of Classical Christian Schools, shares the newly published results of the highly regarded Cardus Educational study. Cardus, a top research firm commissioned by the ACCS, measured the influence of Classical Christian Schools on graduates up to twenty-five years later. Cardus worked with Notre Dame’s Sociology Department to conduct a highly scientific, unbiased, and first of its kind study. Released this month for the first time ever, this 89-page comparative study evaluates a broad spectrum of behaviors, attitudes, beliefs and life outcomes of alumni ages 24-42. Compared with five other types of schools (public, private, Catholic, evangelical Christian, and homeschool), Classical Christian (ACCS) schools produce alumni who stand out as having an influence in the real world. Listen in to hear some of the fascinating results!

In this episode of Rant & Grow, Certified Life Coach Tullio Siragusa's guest Michelle Allaire, a business owner and single mom of three, talks about the desire to focus on her artistry. What role do limiting beliefs play in her journey towards fulfilling her passion for art? Listen and find out how Tullio helps Michelle develop a plan and mantra to help her realize her dreams. Follow Tullio on Twitter and/or Instagram: @tulliosiragusa --- Send in a voice message: https://anchor.fm/tulliosiragusa/message

We can alter how we perceive time. Maybe you feel like time is really scarce, learn about the psychology of how to make time feel more plentiful! [00:00] Intro [01:49] Time and awe [05:34] Time perception [09:29] Buying time [11:50] Making your life seem longer [15:30] What did we learn today?   References: Rudd, M., Vohs, K. D., & Aaker, J. (2012). Awe Expands People’s Perception of Time, Alters Decision Making, and Enhances Well-Being. Psychological Science 23(10) 1130 –1136. https://doi.org/10.1177/0956797612438731 Niiya, Y. (2019). My Time, Your Time, or Our Time ? Time Perception and Its Associations with Interpersonal Goals and Life Outcomes. Journal of Happiness Studies, 20(5), 1439–1455. https://doi.org/10.1007/s10902-018-0007-y Whillans, A. V, Dunn, E. W., Smeets, P., Bekkers, R., & Norton, M. I. (2017). Buying time promotes happiness. PNAS 114(32), 8523–8527. https://doi.org/10.1073/pnas.1706541114 Zhang, J. W., & Howell, R. T. (2011). Do time perspectives predict unique variance in life satisfaction beyond personality traits ? Personality and Individual Differences, 50(8), 1261–1266. https://doi.org/10.1016/j.paid.2011.02.021 Wittmann, M., & Lehnhoff, S. (2005). Age effects in perception of time. Psychological Reports, 97, 921-935. https://doi.org/10.2466/PR0.97.7.921-935

Think Speak Acts SeriesMalaga Campus June 16

In the first segment, Dr. Ted Burns talks with Dr. Irene Katzan about her paper on quality of life outcomes in patients presenting for evaluation of central nervous system tumors. In the second part of the podcast, Dr. Jeff Burns focuses his interview with Dr. Jerold Chun on a 'Landmark study’ showing brain cells revamp their DNA, perhaps sparking Alzheimer’s disease.

1.Quality of Life Outcomes in Patients Presenting for Evaluation of Central Nervous System Tumors 2. [What’s Trending]: 'Landmark study’ shows brain cells revamp their DNA, perhaps sparking Alzheimer’s disease. In the first segment, Dr. Ted Burns talks with Dr. Irene Katzan about her paper on quality of life outcomes in patients presenting for evaluation of central nervous system tumors. In the second part of the podcast, Dr. Jeff Burns focuses his interview with Dr. Jerold Chun on a 'Landmark study’ showing brain cells revamp their DNA, perhaps sparking Alzheimer’s disease.Dr. Ted Burns has served on scientific advisory boards for Argenx, Momenta, received travel funding or speaker honoraria from Argenx, Alexion and received support for consulting activities from UCB Pharma, CSL Behring, Momenta, Argenx. Dr. Irene Katzan has served on editorial boards for Stroke (American Stroke Association), 2014-present Editorial Board - Circulation: Cardiovascular Quality & Outcomes (American Heart Association) 2013 – present. Dr. Irene Katzan has received research from one commercial entity including Novartis Pharmaceuticals and received research support from the following government entity: Ohio Department of Health - Physician Lead for the Ohio Paul Coverdell Stroke Registry, 2007-2020. Dr. Burns has served on the DSMB for NIH-funded trials (non-profit entities); serves on the editorial board for Journal of Alzheimer's Disease; has consulted for Grifols, USA; has served on Eli Lilly Amyvid Speaker's Bureau; and has received research support from Eli Lilly, Avid Radiopharmaceuticals, Toyama Chemical Company, Merck, Biogen, AbbVie, Novartis, vTv Therapeutics, Janssen, and NIH (R01AG058557, R01AG053312, R01AG034614, R01AG03367, R01AG043962, P30AG035982, U10NS077356, UL1TR000001).Dr. Jerold Chun reports no disclosures.

There is no shortage of resources on the power of habits. Many books, podcasts, blogs, etc., are available on the topic, and even though this be true, there is still much to explore. Author, and Habit Guru, James Clear, believes the power of forming good habits is the compounding interest of self improvement. He has written that habits are developed by either default or design. In this episode, we engage our discussion from the perspective, that if we first form our habits, our habits with then form us. Enjoy the show!

Interview with Suzanne V. Arnold, MD, MHA, author of Association of Transcatheter Mitral Valve Repair With Quality of Life Outcomes at 30 Days and 1 Year: Analysis of the Transcatheter Valve Therapy Registry

Interview with Suzanne V. Arnold, MD, MHA, author of Association of Transcatheter Mitral Valve Repair With Quality of Life Outcomes at 30 Days and 1 Year: Analysis of the Transcatheter Valve Therapy Registry

Commentary by Dr. Valentin Fuster

You can learn more at www.inspiredhealthstrategies.com. Dyan is the owner of a patient-focused consultancy, Inspired Health Strategies, LLC (IHS). After spending 20+ years in Big Pharma in traditional sales and marketing roles, in 2007 Dyan began working as a contractor with Sanofi. She was brought in to develop a multi-cultural marketing initiative and Dyan had little hope of making much of an impact until she realized that Sanofi was serious as evidenced by their commitment to a hefty budget and an enterprise-wide effort. She knew that, given her past experience combined with a non-traditional approach to market research, she could help Sanofi develop a groundbreaking program. What was developed was a program that incorporated the patient's ecosystem into a branded and non-branded initiative that resulted in documented behavior change and significant contribution to the bottom-line. The Community Health Partnership (CHP) changed her brain – she now understood the opportunity the industry was missing by not understanding the value of the patient. Since that Sanofi initiative Dyan has been an evangelist for patient engagement. But after years of trying to push the industry in this patient-focused direction she was ready to give up…until she attended the March 19, 2018 FDA meeting regarding the Patient-Focused Drug Development (PFDD) initiative. The FDA was going to actually issue guidance that echoes Dyan's mantra – that patients should be involved in drug development, in a meaningful way, from pre-Investigative New Drug Application (IND) through commercial. This has rejuvenated Dyan's efforts as she watches and helps the industry sort out how to comply with this guidance. Compliance will demand a change in thinking in the industry and will produce great results for patients. Dyan's efforts have been recognized by her being included in the PharmaVoice 100 Innovators in Life Sciences. Dyan has been published in several industry journals including Pharmaceutical Commerce and The Journal of Patient Adherence and is a frequent speaker at industry meetings. You can learn more about PFDD and see case studies on the work of IHS at Dyan's website www.inspiredhealthstrategies.com, follow Dyan @InspiredHealth_ 00:40 Patient Reported Outcomes, PRO. 01:30 Are patient reported outcomes unscientific? 02:20 Learning to accept the validity of PRO data for what it is. 02:55 Patient-Focused Drug Development - PFDD. 04:10 Closing the loop with patients. 04:55 “It's hard enough to get people to participate in a clinical trial without making things tough for them.” 10:20 “We're starting to focus more on real world, in real time.” 13:20 Clinical Outcomes vs Quality of Life Outcomes 18:50 EP157 with Dr Ethan Basch 22:40 “We don't always know everything.” 25:50 Trying to improve patient adherence. 26:55 Why focusing on behavior increases patient engagement. 27:15 “It's about engagement.” 30:35 You can learn more at www.inspiredhealthstrategies.com.

The importance of being mindful of the consequences of all those seemingly small decisions

Outcomes five and twelve years Later — Janet Rosenbaum shares findings from study that compares #edu & criminal justice outcomes for 480 youth suspended from schools with those of 1,193 matched non-suspended youth. Download report: http://bit.ly/2GzyQuV

Prof Ganz talks to ecancertv at SABCS 2015 about secondary end point data from the phase III NSABP B-35 clinical trial that compared 5 years’ treatment with anastrozole or tamoxifen in postmenopausal women with ductal carcinoma in situ (DCIS). The primary end point results of the NSABP B-35 trial were reported at the American Society of Clinical Oncology 2015 annual meeting and showed that anastrozole was at least as effective and safe as tamoxifen. There was a slight advantage of anastrozole perhaps, Dr Ganz notes in the interview. Indeed women where more likely to remain breast-cancer free at 10 years if they had received the aromatase inhibitor. Patient reported outcomes such as quality of life were reported in a sub-study of the trial and Dr Ganz reported data on more than 1000 women who has participated and completed the Short-Form 12. There were no differences, however, between the women treated with anastrozole and those treated with tamoxifen when using the Physical Component Summary (p=0.16) or the Mental Component Summary (p=0.38) of this questionnaire. As expected there were differences in terms of the symptoms, with the typical tamoxifen side effects of hot flashes seen and more musculoskeletal pain and vaginal pain and discomfort during sex in those treated with anastrozole. What these data show is that there are choices, Dr Ganz says. Before tamoxifen was the only approved option in DCIS but the NSABP B-35 and other trial data now show that aromatase inhibitor therapy, specifically anastrozole, is also of benefit.

My guest today is a theoretical neuroscientist, technologist and entrepreneur who was named one of Inc. Magazine's top 10 women to watch in tech in 2013. She co-founded Socos, a cutting-edge startup which applies cognitive modeling to create adaptive, personalized educational technology. She is also a visiting scholar at UC Berkeley's Redwood Center for Theoretical Neuroscience pursuing her research in neuroprosthetics. Previously, she was a junior fellow at Standford's Mind, Brain & Computation Center and earned her Ph.D. from Carnegie Mellon. Her work and research has received a ton of media attention including the New York Times, NPR, Nature, O Magazine, Forbes, and The Atlantic. In this interview, we discuss her INCREDIBLE STORY, how technology will be used to predict our learning and performance, how we can change life outcomes, how prosthetic devices will be used to alter and repair or brains and bodies, and the very realistic possibility of a hyper-intelligent superhuman race… and that's just in the first 30 minutes.

Commentary by Dr. Valentin Fuster

Gender inequality in workplaces and in homes around the globe reflects individual attitudes and abilities, intra-household bargaining and legal and socio-cultural influences. Research that considers factors across the individual, household and cultural levels simultaneously is essentially nonexistent. This paper explores how gender attitudes are shaped by the national context, how these shape intra-household bargaining, and how women’s and men’s lives at work and at home are altered in the process. Speaker: Kathleen McGinn, Cahners-Rabb Professor of Business Administration, Harvard Business School

This podcast covers the JBJS issue for March 2014. Featured are articles covering: A Randomized Clinical Trial Comparing Open and Arthroscopic Stabilization for Recurrent Traumatic Anterior Shoulder Instability - Two-Year Follow-up with Disease-Specific Quality-of-Life Outcomes; recorded commentary by Dr. Dahm; Evaluation of Physical Performance Level as a Fall Risk Factor in Women with a Distal Radial Fracture; recorded commentary by Dr. Benson; The Relationship Between Medical Malpractice Litigation and Parent Reports of Patient Function Following Neonatal Brachial Plexus Palsy; Sensitivity of Frozen Section Histology for Identifying Propionibacterium acnes Infections in Revision Shoulder Arthroplasty

This podcast covers the JBJS issue for March 2014. Featured are articles covering: A Randomized Clinical Trial Comparing Open and Arthroscopic Stabilization for Recurrent Traumatic Anterior Shoulder Instability - Two-Year Follow-up with Disease-Specific Quality-of-Life Outcomes; recorded commentary by Dr. Dahm; Evaluation of Physical Performance Level as a Fall Risk Factor in Women with a Distal Radial Fracture; recorded commentary by Dr. Benson; The Relationship Between Medical Malpractice Litigation and Parent Reports of Patient Function Following Neonatal Brachial Plexus Palsy; Sensitivity of Frozen Section Histology for Identifying Propionibacterium acnes Infections in Revision Shoulder Arthroplasty

LIFE’S DRIVERS: BELIEFS AND VOWS with PENNY COHEN, LCSW. Penny Cohen, is a psychotherapist, life coach, author, counselor and lecturer. She is the author of the book Personal Kabbalah. On this show we will be discussing how beliefs and vows serve as the basis of many of our life’s decisions and outcomes.

This podcast, How Would Early Treatment Affect Disease and Quality-of-Life Outcomes in Spondyloarthritis (SpA)?, features a telephone interview with Professor Joachim Sieper.

Family background plays a crucial role in childrens outcomes in later life. But what is the specific impact of health in childhood on educational success? Romesh Vaitilingam chats to Professor Janet Currie (Columbia University) at the American Economic Association meetings in New Orleans.