POPULARITY
8 episodes with hemolytic
3 episodes with hemolytic
3 episodes with hemolytic
7 episodes with hemolytic
2 episodes with hemolytic
2 episodes with hemolytic
2 episodes with hemolytic
2 episodes with hemolytic
2 episodes with hemolytic
*Content warning: birth trauma, medical trauma, medical neglect, racism, death of an infant, infant loss, death, homicide, maternal loss, mature and stressful themes, sexual assault, disordered eating. *Free + Confidential Resources + Safety Tips: somethingwaswrong.com/resources Sources: American College of Nurse Midwiveshttps://midwife.org/ American College of Obstetricians and Gynecologists (ACOG)https://www.acog.org/ Authorities explain lack of charges in Fort Mill birthing center deathhttps://www.charlotteobserver.com/news/local/crime/article23277849.html Births in the United States, 2022https://www.cdc.gov/nchs/products/databriefs/db477.htm A brain-dead woman's pregnancy raises questions about Georgia's abortion lawhttps://www.npr.org/2025/05/21/nx-s1-5405542/a-brain-dead-womans-pregnancy-raises-questions-about-georgias-abortion-law A Brief History of Midwifery in Americahttps://www.ohsu.edu/womens-health/brief-history-midwifery-america Constructing the Modern American Midwife: White Supremacy and White Feminism Collidehttps://nursingclio.org/2020/10/22/constructing-the-modern-american-midwife-white-supremacy-and-white-feminism-collide/ The Controversial Birth of American Gynecologyhttps://researchblog.duke.edu/2023/10/27/the-controversial-birth-of-american-gynecology/ Direct Entry Midwives Across the Nationhttps://www.networkforphl.org/wp-content/uploads/2023/05/Direct-Entry-Midwives-50-State-Survey.pdf FDA raids Miami birth center; Placentas, medical records confiscatedhttps://mommyblawg.blogspot.com/2009/01/fda-raids-miami-birth-center-placentas.html Fort Mill birthing center closes following third child deathhttps://www.wbtv.com/story/28083972/fort-mill-birthing-center-closes-following-third-child-death/ Exhibit Recognizes African American Midwiveshttps://infocus.nlm.nih.gov/2010/02/05/exhibit_recognizes_african_ame/ Health E-Stat 100: Maternal Mortality Rates in the United States, 2023https://www.cdc.gov/nchs/data/hestat/maternal-mortality/2023/maternal-mortality-rates-2023.htm#:~:text=In2023%2C669womendied,rateof22.3in2022 Hemolytic disease of the newbornhttps://medlineplus.gov/ency/article/001298.htm The Historical Significance of Doulas and Midwiveshttps://nmaahc.si.edu/explore/stories/historical-significance-doulas-and-midwives Home Births in the U.S. Increase to Highest Level in 30 Yearshttps://www.cdc.gov/nchs/pressroom/nchs_press_releases/2022/20221117.htm Honest Midwife Bloghttps://honestmidwife.com/ International School Of Midwiferyhttps://www.mapquest.com/us/florida/international-school-of-midwifery-531273160 March of Dimeshttps://www.marchofdimes.org/peristats/about-us March of Dimes, Delivery Method https://www.marchofdimes.org/peristats/data?dv=ms&lev=1&obj=9®=99&slev=1&stop=86&top=8& March of Dimes, Maternity Care Deserthttps://www.marchofdimes.org/peristats/data?top=23 Maternal Mortality in the United States After Abortion Banshttps://thegepi.org/maternal-mortality-abortion-bans/#:~:text=InthefirstfullyearofTexas%27sstateabortionban,15 Maternal Mortality: How the U.S. Compares to Other Rich Countrieshttps://www.usnews.com/news/best-countries/articles/2024-06-04/how-the-u-s-compares-to-other-rich-countries-in-maternal-mortality Medical Exploitation of Black Womenhttps://eji.org/news/history-racial-injustice-medical-exploitation-of-black-women/ National Midwifery Institutehttps://www.nationalmidwiferyinstitute.com/midwifery Necrotizing Fasciitishttps://my.clevelandclinic.org/health/diseases/23103-necrotizing-fasciitisNew Pregnancy Justice Report Shows High Number of Pregnancy-Related Prosecutions in the Year After Dobbshttps://www.pregnancyjusticeus.org/press/new-pregnancy-justice-report-shows-high-number-of-pregnancy-related-prosecutions-in-the-year-after-dobbs/#:~:text=Thereportdocumentsthati,%2Cpregnancyloss%2Corbirth. North American Registry of Midwives (NARM)https://narm.org/ Physician Suicidehttps://www.acep.org/life-as-a-physician/wellness/wellness/wellness-week-articles/physician-suicide Preeclampsiahttps://my.clevelandclinic.org/health/diseases/17952-preeclampsia Preeclampsia: Signs & Symptomshttps://www.preeclampsia.org/signs-and-symptomsRace Maternal Mortality in the U.S.: A History of Midwiferyhttps://wmberks.pages.wm.edu/2023/04/30/race-maternal-mortality-in-the-u-s-a-history-of-midwifery/ The Racist History of Abortion and Midwifery Banshttps://www.aclu.org/news/racial-justice/the-racist-history-of-abortion-and-midwifery-bans Reasons Obstetricians Are At High Risk For Claims Of Medical Malpracticehttps://www.gilmanbedigian.com/reasons-obstetricians-are-at-high-risk-for-claims-of-medical-malpractice/#:~:text=Overall%2Cabout85%25ofOB,about95%25ofthetime. The Regulation of Professional Midwifery in the United Stateshttps://midwife.org/wp-content/uploads/2024/09/Jefferson-2021-Regulation-Professional-Midwifery.pdf She said she had a miscarriage — then got arrested under an abortion lawhttps://www.washingtonpost.com/investigations/interactive/2024/abortion-law-nevada-arrest-miscarriage/ She was accused of murder after losing her pregnancy. SC woman now tells her storyhttps://www.cnn.com/2024/09/23/health/south-carolina-abortion-kff-health-news-partner South Carolina Department of Public Health, Midwifery Licensinghttps://dph.sc.gov/professionals/healthcare-quality/licensed-facilities-professionals/midwifery-licensing#:~:text=DPHlicensesmidwivesinaccordancewithRegulation,inadditiontootherprescribedrequirementson State investigating Dallas birth center and midwives, following multiple complaints from patientshttps://www.wfaa.com/article/news/local/investigates/state-investigating-dallas-birth-center-midwives-following-multiple-complaints-from-patients/287-ea77eb18-c637-44d4-aaa2-fe8fd7a2fcef The State of Reproductive Health in the United Stateshttps://thegepi.org/state-of-reproductive-health-united-states/ Texas Department of Licensing and Regulation (TDLR)https://www.tdlr.texas.gov/ Texas Maternal Mortality and Morbidity Review Committee and Department of State Health Services Joint Biennial Report 2024https://www.dshs.texas.gov/sites/default/files/legislative/2024-Reports/MMMRC-DSHS-Joint-Biennial-Report-2024.pdf Uses of Misoprostol in Obstetrics and Gynecologyhttps://pmc.ncbi.nlm.nih.gov/articles/PMC2760893/ Vicarious trauma: signs and strategies for copinghttps://www.bma.org.uk/advice-and-support/your-wellbeing/vicarious-trauma/vicarious-trauma-signs-and-strategies-for-coping Vital Signs: Maternity Care Experiences — United States, April 2023https://www.cdc.gov/mmwr/volumes/72/wr/mm7235e1.htm#:~:text=Discussion,%2CHispanic%2Candmultiracialmothers. 2022 Direct Entry Midwives Fact Sheethttps://www.dshs.texas.gov/sites/default/files/chs/hprc/publications/2022/DirectEntryMidwife2022FactSheetA.pdf *SWW S23 Theme Song & Artwork: Thank you so much to Emily Wolfe for covering Glad Rag's original song, U Think U for us this season!Hear more from Emily Wolfe:https://www.emilywolfemusic.com/instagram.com/emilywolfemusicGlad Rags: https://www.gladragsmusic.com/ The S23 cover art is by the Amazing Sara StewartFollow Something Was Wrong:Website: somethingwaswrong.com IG: instagram.com/somethingwaswrongpodcastTikTok: tiktok.com/@somethingwaswrongpodcast Follow Tiffany Reese:Website: tiffanyreese.me IG: instagram.com/lookiebooSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode, we review the high-yield topic Hemolytic Uremic Syndrome (HUS) from the Heme section at Medbullets.com Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets Linkedin: https://www.linkedin.com/company/medbullets
In this week's episode we'll learn about C3-targeted therapy in autoimmune hemolytic anemias. Based on results of an open-label, phase 2 study, pegcetacoplan was well-tolerated, with encouraging efficacy, particularly in patients with cold agglutinin disease. After that: Venetoclax sensitivity testing to predict AML response. In a significant step toward precision medicine, researchers have validated an assay capable of predicting response to the venetoclax-azacitidine regimen. Finally, an improved basic understanding of human coagulation factor XIII. Investigators present the cryo-electron microscopy structure of Factor XIII complex, providing new insights into etiology and the deleterious effects of certain specific mutations.Featured Articles:Safety and efficacy of pegcetacoplan treatment for cold agglutinin disease and warm antibody autoimmune hemolytic anemiaEx vivo venetoclax sensitivity predicts clinical response in acute myeloid leukemia in the prospective VenEx trialCryo-EM structure of the human native plasma coagulation factor XIII complex
On this episode of Thal Pals, NinaMaria concludes our two-part series on nutrition with guest Tamara Schryver, a nutrition scientist and president of the Thrive with Pyruvate Kinase Deficiency Organization. They dive into the roles of antioxidants for those with hemolytic anemias, the controversial debate over vitamin A and E supplements, and the significance of a balanced diet. They also discuss the importance of physical activity for individuals with Thal and PKD, and how dietitians and healthcare providers can collaborate to create effective health plans. SHOW DESCRIPTION Thal Pals: The Alpha Beta Revolution Podcast is intended for patients, caregivers, providers, and the greater community of people who are impacted by thalassemia. Each episode strives to provide listeners with critical education, the latest scientific updates, and voices from the thalassemia community. Learn more about thalassemia by visiting RethinkThalassemia.com. Join an inclusive community and build connections with other hemolytic anemia allies by following @AllyVoicesRising on Instagram. Thal Pals is sponsored by Agios Pharmaceuticals Inc. Visit Agios.com to learn more. This podcast is intended for informational and educational purposes only and is not intended as medical advice. Please speak with your healthcare professional before making any treatment decisions. TRANSPARENCY STATEMENT Thal Pals: The Alpha Beta Revolution Podcast is made possible by Agios Pharmaceuticals Inc. Visit Agios.com to learn more. The following Agios-supported programs are intended for informational and educational purposes only and are not intended as medical advice. Please speak with your healthcare professional before making any treatment decisions. Host and guest featured in this episode have been compensated for their time.
Resilience is part of the DNA in agriculture, but there's a massive difference when the adversity being faced is away from the farm and involves a loved one.Grower James Rickert and his wife Casey faced such adversity when their young daughter Emersyn contracted Hemolytic-uremic syndrome caused by E.coli.Earlier this year, Emersyn battled through a multi system shutdown, kidney failure, coma, seizures, neurological complications, a collapsed lung and multiple infections.After 10 weeks in the hospital, Emersyn is home and vastly improved. She started her first day in kindergarten and even had a visit with Santa and Mrs. Claus. The Rickert family hopes Emersyn's courage will inspire others facing huge life challenges.“She's my hero, and I don't know how she does what she does every day,” Casey said. “She's still processing the trauma in her own way. Nothing phases this kid. She is defying the odds after what she went through.”“I look at life differently,” James said. “I realize that every day with my family is special. I have never appreciated it as much as I do today.”Emersyn continues her recovery and recently made a Gingerbread house with a horse on top. She also put her Christmas request in to Santa Claus for a tiny dog.
Contributor: Alec Coston MD Educational Pearls: Causes of seizures in a fairly well-appearing child with diarrhea: Electrolyte abnormalities: hypocalcemia, hyponatremia Also hyperkalemia which causes arrhythmias and syncope - can appear like seizures Hypoglycemia If the child has diarrhea and appears very sick, differential diagnosis may include: Hemolytic uremic syndrome (HUS): simultaneous occurrence of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury Typically caused by Shiga-like toxin producing Escherichia coli (also known as EHEC, or enterohemorragic E. coli) One of the main causes of acute kidney injury in children Toxic ingestions such as salicylates, lead, or iron In this case, the child had a seizure but appeared well and was afebrile: Consult with neurology led to a diagnosis of benign convulsions with mild gastroenteritis (CwG) First identified in 1982 in Japan Viral gastroenteritis with diarrhea and convulsions but does not include fever, severe dehydration, or electrolyte abnormalities Uncommon illness caused by rotavirus and norovirus pathogens Criteria for discharge is similar to a febrile seizure - the patient had one seizure that lasted less than 15 minutes and he quickly returned to his baseline, so he was able to be safely discharged home This diagnosis does not predispose him to epilepsy later in life References Lee YS, Lee GH, Kwon YS. Update on benign convulsions with mild gastroenteritis. Clin Exp Pediatr. 2022 Oct;65(10):469-475. doi: 10.3345/cep.2021.00997. Epub 2021 Dec 27. PMID: 34961297; PMCID: PMC9561189. Mauritz M, Hirsch LJ, Camfield P, et al. Acute symptomatic seizures: an educational, evidence-based review. Epileptic Disorders. 2200;1(1). doi:https://doi.org/10.1684/epd.2021.1376 Noris, Marina*; Remuzzi, Giuseppe*, †. Hemolytic Uremic Syndrome. Journal of the American Society of Nephrology 16(4):p 1035-1050, April 2005. | DOI: 10.1681/ASN.2004100861 Summarized by Meg Joyce, MS1 | Edited by Meg Joyce & Jorge Chalit, OMS3 Donate: https://emergencymedicalminute.org/donate/
On this episode of Thal Pals, NinaMaria hosts Tamara Schryver, president of the Thrive with Pyruvate Kinase Deficiency Organization. They discuss the importance of nutrition for patients with hemolytic anemias such as thalassemia and PKD. Tamara offers practical dietary tips and emphasizes the significance of nutrient-dense foods and vitamins. Stay tuned for the next episode, where they delve deeper into these topics. SHOW DESCRIPTION Thal Pals: The Alpha Beta Revolution Podcast is intended for patients, caregivers, providers, and the greater community of people who are impacted by Thalassemia. Each episode, Thal Pals strives to provide listeners with critical education, the latest scientific updates, and voices from the Thalassemia community. TRANSPARENCY STATEMENT Thal Pals: The Alpha Beta Revolution Podcast is made possible by Agios Pharmaceuticals Inc. Visit Agios.com to learn more. The following Agios-supported programs are intended for informational and educational purposes only and are not intended as medical advice. Please speak with your healthcare professional before making any treatment decisions. Hosts featured in this episode have been compensated for their time.
CME credits: 0.25 Valid until: 18-09-2025 Claim your CME credit at https://reachmd.com/programs/cme/warm-autoimmune-hemolytic-anemia-how-antibody-based-therapies-are-revolutionizing-its-management/26371/ Warm autoimmune hemolytic anemia (wAIHA) is a rare condition characterized by the premature destruction of red blood cells mainly by pathogenic IgG optimally active at 37oC. Innovative targeted therapies to address wAIHA are emerging, and many are likely to greatly improve patient outcomes when they reach the clinic. Join Drs. Caroline Piatek and Irina Murakhovskaya as they discuss in detail current and emerging non-antibody and monoclonal antibody therapies for wAIHA and how each has the potential to dramatically improve the treatment landscape for wAIHA.=
CME credits: 0.25 Valid until: 08-08-2025 Claim your CME credit at https://reachmd.com/programs/cme/innovations-in-the-management-of-hemolytic-disease-of-the-fetus-and-newborn-the-role-of-the-neonatal-fc-receptor-fcrn-pathway/16045/ Hemolytic disease of the fetus and newborn (HDFN) is an alloimmune disorder between the mother and fetus, one with significant risk for dire health consequences for both. Fortunately, a better understanding of the neonatal Fc receptor (FcRn) pathway along with the emergence of an inhibitor of this pathway has brought with it an opportunity to greatly reduce the potential harm associated with HDFN. Join us as Drs. Kenneth Moise and Kara Markham discuss the pathophysiology of HDFN and present key clinical data that may change the landscape of medical intervention for HDFN.=
In this episode, pediatric nephrologist Dr. Myda Khalid (Indiana) teaches us about hemolytic uremic syndrome. Join us as we learn about the clinical manifestations of HUS, different methods for stool testing, and the role of interventions including fluids, transfusions, and renal replacement therapy.
Beyond the Pearls: Cases for Med School, Residency and Beyond (An InsideTheBoards Podcast)
Today's Episode Charlee reviews chapter 10 from the Pediatric Morning Report book. The obstetric service is monitoring a 33-year-old G9P2071 pregnant female with a history of a prior pregnancy ending in intrauterine fetal demise at 8 months of gestation. A prenatal ultrasound performed at 29 weeks of gestation shows worsening anemia, as evidenced by an elevated peak systolic velocity (PSV) through the middle cerebral arteries. Today's Host Charlee Quarless is a 3rd year medical student at Ross University. About Dr. Raj Dr Raj is a quadruple board certified physician and associate professor at the University of Southern California. He was a co-host on the TNT series Chasing the Cure with Ann Curry, a regular on the TV Show The Doctors for the past 7 seasons and has a weekly medical segment on ABC news Los Angeles. More from Dr. Raj www.BeyondThePearls.net The Dr. Raj Podcast Dr. Raj on Twitter Dr. Raj on Instagram Want more board review content? USMLE Step 1 Ad-Free Bundle Crush Step 1 Step 2 Secrets Beyond the Pearls The Dr. Raj Podcast Beyond the Pearls Premium USMLE Step 3 Review MedPrepTGo Step 1 Questions Learn more about your ad choices. Visit megaphone.fm/adchoices
CardioNerds cofounder, Amit Goyal joins Dr. Belal Suleiman, Dr. Nkiru Osude, and Dr. David Elliott from Duke University. They discuss a case of severe mitral paravalvular regurgitation complicated by hemolytic anemia. Expert commentary is provided by Dr. Andrew Wang. Audio editing by CardioNerds Academy Intern, student doctor Adriana Mares. US Cardiology Review is now the official journal of CardioNerds! Submit your manuscript here. CardioNerds Case Reports PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Case Media - Severe Mitral Paravalvular Regurgitation Complicated by Hemolytic Anemia - Duke University
Recorded LIVE! At Johns Hopkins Internal Medicine Grand Rounds Step up your anemia game as we explore the causes and diagnostic approach for macrocytic anemia, what to do with a reticulocyte count, the differential diagnosis for hemolytic anemia, the significance of the direct antiglobulin test, and diagnosis and management pearls for autoimmune hemolytic anemia (AIHA) and myelodysplastic syndrome (MDS). Plus, common questions and concerns regarding folate supplementation and the use of bone marrow biopsies. We're joined by hematologist and pun enthusiast Dr. Rakhi Naik MD, MHS, @redcell_doc @hopkinsheme. Claim CME for this episode at curbsiders.vcuhealth.org! Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME Show Segments 00:00 Intro and Guest intro 05:53 Case 1: Elise - Macrocytic Anemia 14:59 Case 2: Jane - Hemolytic Anemia 23:24 Testing for Underlying Causes of Autoimmune Hemolytic Anemia 24:40 Association of Autoimmune Hemolytic Anemia with Lymphomas 25:10 Autoimmune Hemolytic Anemia: Diagnosis and Treatment 26:06 Management Approach for Autoimmune Hemolytic Anemia 27:30 Considerations for Outpatient Treatment of Autoimmune Hemolytic Anemia 28:18 Clotting Risk in Autoimmune Hemolytic Anemia 29:20 Treatment Options for Autoimmune Hemolytic Anemia 30:42 Long-Term Prognosis and Recurrence of Autoimmune Hemolytic Anemia 33:32 Diagnostic Challenges in Myelodysplastic Syndrome 35:00 Considerations for Folate Supplementation 36:24 Factors to Consider in the Management of Myelodysplastic Syndrome 39:30 When to Perform a Bone Marrow Biopsy in Myelodysplastic Syndrome 41:25 Shared Decision-Making in the Treatment of Myelodysplastic Syndrome Credits Writer and Producer: Matthew Watto MD, FACP Show Notes: Matthew Watto MD, FACP Cover Art and Infographic: Matthew Watto MD, FACP Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP Reviewer: Fatima Syed MD, MSc Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Guest: Rakhi P. Naik MD, MHS Sponsor: Beginly Health Visit beginlyhealth.com/curbsiders job matching platform for every Physician and Advanced Practice Clinician, from training to practice. Sponsor: Freed You can try Freed for free right now by going to freed.ai. And listeners of Curbsiders can use code CURB50 for $50 off their first month. Sponsor: Babbel Get up to 60% off your Babbel subscription, for a limited time, at Babbel.com/CURB.
Alexandre Nguyen and Manuel Schiff share the story of two siblings with severe haemolytic anaemia developing in previously well controlled methionine synthase reductase deficiency. Late-onset refractory hemolytic anemia in siblings treated for methionine synthase reductase deficiency: A rare complication possibly prevented by hydroxocobalamin dose escalation? Alexandre Nguyen, et al https://doi.org/10.1002/jmd2.12422
In this part 2 episode, we dive into the pathology and symptoms of Babesiosis, exploring how the Babesia parasite infects red blood cells and evades the immune system. We discuss various labs and biomarkers to look out for. We then address various treatment protocols featuring anti-malarials including herbal supplements such as artemisinin and cryptolepis, and proteolytic enzymes like lumbrokinase and nattokinase. Additionally, we cover the use of methylene blue and its impact on Babesia parasites. Topics: 1. Introduction - Brief overview of Babesiosis and previous discussion - Overview of Babesia infection and its impact on red blood cells (RBCs) 2. Pathology of Babesiosis - Infection and multiplication within RBCs - Mechanisms of immune evasion - Expression of specific proteins on RBC surface - Adherence to capillary endothelial cells - Avoidance of spleen clearance - Antigenic variation and immune system evasion 3. Symptoms of Babesiosis - Air hunger - High fever - Severe fatigue - Muscle and joint pain - Persistent headaches - Jaundice - Dark urine - Organ failure (in severe cases) 4. Labs and Markers for Babesiosis - Hematological markers - Hemolytic anemia - Thrombocytopenia - Leukopenia - Hemoglobinuria - Hyperbilirubinemia - Elevated LDH levels - Reticulocytosis - Other markers - High C4a levels - Low CD57 count 5. Protocols - Importance of medical supervision and potential Herxheimer reaction - Overview of treatment approaches 6. Anti-Malarial Protocols for Babesiosis - Prescription Medications - Mepron (Atovaquone), Mechanism of action: inhibition of mitochondrial electron transport chain. - Azithromycin, Mechanism of action: blocking protein synthesis. - Herbal Approaches for Babesiosis - Artemisinin: Derived from sweet wormwood plant. Mechanism of action: production of reactive oxygen species (ROS). - Cryptolepis: Bioactive compound is Cryptolepine, Mechanism of action: disruption of DNA synthesis. 7. Proteolytic Enzymes - Lumbrokinase - Nattokinase 8. Methylene Blue - Synthetic dye - Mechanism of action: disrupting mitochondrial function and generating ROS within Babesia - Administration methods and effects 9. Conclusion - Recap of supplements and treatments discussed - Emphasis on individualized treatment plans, bioindividuality, and working with a medical physician Thank you to our episode sponsor: Liver Medic Use code Chloe20 to save 20% on "Leaky Gut Repair" Brendan's YouTube Channel https://x.com/livermedic Thanks for tuning in! Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" If you liked this episode, please leave a rating and review or share it to your stories over on Instagram. If you tag @synthesisofwellness, Chloe would love to personally thank you for listening! Follow Chloe on Instagram @synthesisofwellness Follow Chloe on TikTok @chloe_c_porter Visit synthesisofwellness.com to purchase products, subscribe to our mailing list, and more! Or visit linktr.ee/synthesisofwellness to see all of Chloe's links, schedule a BioPhotonic Scanner consult with Chloe, or support the show! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support
In the 1930's (and before), there was a mysterious cause of infant mortality. An astonishing number of newborns were victim to a mismatch between their blood type, and that of their mothers. Doctors at the time were not sure why this was happening. This is the story of the discovery of the cure for that condition and a man who went above and beyond for six decades to help prevent it in his part of the world.Sources:-https://en.wikipedia.org/wiki/James_Harrison_(blood_donor)-https://www.cnn.com/2018/05/11/health/james-harrison-blood-donor-retires-trnd/index.html-https://www.washingtonpost.com/news/to-your-health/wp/2018/05/12/for-six-decades-the-man-with-the-golden-arm-donated-blood-and-saved-2-4-million-babies/-https://www.npr.org/2015/06/14/414397424/man-with-the-golden-arm-donates-blood-thats-saved-2-million-babies-https://en.wikipedia.org/wiki/Rh_disease ----- Patreon Page (support the show) -----Submit a Question for Non-Medical Advice Segment (website form with instructions)-----Podcast Linktree (social media links / reviews / ratings)-----DrMqx (follow Dr. Max on Twitch)
HOST: Andy Herber, P.A.-C. GUEST: Ronald S. Go, M.D. Join our host, Andy J. Herber, P.A.-C., as he discusses the complete blood count (CBC), which is one of the most ordered laboratory tests in the primary care setting. Providers are frequently tasked with evaluating all aspects of the CBC. A keen understanding of this laboratory test is essential to providing quality care for patients. Joining the first episode of this series is renown Mayo Clinic Hematologist, Ronald S. Go, M.D., who will be discussing evaluating abnormalities, hemoglobin and differing types of anemia. Learn more about our Lab Medicine Edition here Connect with the Mayo Clinic's School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
I read from erythrism to escadrille. Erythropoiesis is the process of making red blood cells and until you're about 5 years old, "The bone marrow of essentially all the bones produces red blood cells." https://en.wikipedia.org/wiki/Erythropoiesis WARNING: This link about "erythroblastosis fetalis" has a tough-to-look-at picture. https://en.wikipedia.org/wiki/Hemolytic_disease_of_the_newborn ESB seems like it has a lot of uses, but I don't love that it's used on animals. But I get it. Scientists aren't going to jump to humans right away. https://en.wikipedia.org/wiki/Electrical_brain_stimulation The word of the episode is "erythrocyte". Theme music from Tom Maslowski https://zestysol.com/ Merchandising! https://www.teepublic.com/user/spejampar "The Dictionary - Letter A" on YouTube "The Dictionary - Letter B" on YouTube "The Dictionary - Letter C" on YouTube "The Dictionary - Letter D" on YouTube "The Dictionary - Letter E" on YouTube Featured in a Top 10 Dictionary Podcasts list! https://blog.feedspot.com/dictionary_podcasts/ Backwards Talking on YouTube: https://www.youtube.com/playlist?list=PLmIujMwEDbgZUexyR90jaTEEVmAYcCzuq https://linktr.ee/spejampar dictionarypod@gmail.com https://www.facebook.com/thedictionarypod/ https://www.threads.net/@dictionarypod https://twitter.com/dictionarypod https://www.instagram.com/dictionarypod/ https://www.patreon.com/spejampar https://www.tiktok.com/@spejampar 917-727-5757
Next in our heme consult series is all about the workup and management of warm autoimmune hemolytic anemia (wAIHA), a very scary situation! These patients can often be very sick and there can be a lot of underlying issues that may be causing this to occur. Rest assured- after this episode, you'll be a pro at identifying this disorder and know how to manage it should you ever come across this. If you have not done so already, we recommend you check out our initial episode about hemolytic anemias (Episode 091)Content: - How do we work up warm autoimmune hemolytic anemia (wAIHA)?- Is it safe to transfuse patients with wAIHA? What about DVT prophylaxis? - What is the approach to initial treatment of wAIHA? How do manage patients once their hemolysis stabilizes? - How do we approach more refractory or relapsed cases? ** Want to review the show notes for this episode and others? Check out our website: https://www.thefellowoncall.com/our-episodesLove what you hear? Tell a friend and leave a review on our podcast streaming platforms!Twitter: @TheFellowOnCallInstagram: @TheFellowOnCallListen in on: Apple Podcast, Spotify, and Google Podcast
In the next part of this heme consult series, we discuss several congenital causes of hemolytic anemias. These diseases are relatively rare, but in patients presenting with concerns for hemolysis on history and on labs, but with a negative DAT, it is important to have these in your differential diagnosis! We take you through how to think about these disorders, their diagnosis, and management. If you have not done so already, be sure to check out Episode 091 where we discuss our initial approach to the diagnosis of hemolytic anemias. We also discuss the most common inherited cause of hemolytic anemia, G6PD deficiency, in that episode!Content: - When should we suspect inherited causes of hemolytic anemia?- What are important examples of membranopathies that can cause hemolytic anemia?- What are important enzyme deficiencies that can cause hemolytic anemia? ** Want to review the show notes for this episode and others? Check out our website: https://www.thefellowoncall.com/our-episodesLove what you hear? Tell a friend and leave a review on our podcast streaming platforms!Twitter: @TheFellowOnCallInstagram: @TheFellowOnCallListen in on: Apple Podcast, Spotify, and Google Podcast
It's time for another heme consult series, this time focusing on hemolytic anemias. In this multi-part series, we will go through our approach to thinking about concerns for hemolytic anemias. This is super high yield for anyone who cares for patients, especially those in hematology/oncology. It's not uncommon to get a consult on the heme consult service for assistance with diagnosis and management of suspected hemolytic anemias! Content: - What is "hemolytic anemia"?- When should we suspect hemolytic anemias?- What is the workup for acquired hemolytic anemias? - What is G6PD deficiency? When should we suspect this? ** Want to review the show notes for this episode and others? Check out our website: https://www.thefellowoncall.com/our-episodesLove what you hear? Tell a friend and leave a review on our podcast streaming platforms!Twitter: @TheFellowOnCallInstagram: @TheFellowOnCallListen in on: Apple Podcast, Spotify, and Google Podcast
Hemolytic disease of the fetus and newborn is a rare autoantibody condition for which there is no approved therapy. It causes the mother's immune system to attack and breakdown the red blood cells in her fetus or newborn. It is one of more than 10 immunological and neurological indications for which Johnson & Johnson is developing its experimental monoclonal antibody nipocalimab. We spoke to Katie Abouzahr, vice president of the autoantibody portfolio and maternal fetal disease area leader for Johnson and Johnson, about hemolytic disease of the fetus and newborn, the challenges of developing a therapy for a rare condition in pregnant women, and why nipocalimab has the potential to be a pipeline in a product.
I hope you enjoy this podcast. If you are interested in the Stem Enhance supplement I mention in the podcast then today is the start of Black Friday and you can buy one and get one tub free!https://onlinecoach.cerule.com/www/shop00:01 Blood glucose management with low carb and carnivore diets- Bart Kay and Coach Stephen discuss the importance of blood glucose management for people on low carb and carnivore diets.- Despite having well-managed blood glucose levels, some individuals may still have high HbA1c levels.02:18 Red blood cell lifespan affects HbA1c accuracy.- The finger prick test can help identify faulty glucose monitors.- Hemolytic anemia can result in artificially low HbA1c levels.06:50 High A1C levels may not be problematic if there are no spikes in blood glucose levels.- The assumption that abnormal blood glucose levels require intervention is questionable without evidence of risk of disease.09:02 Blood glucose levels show spikes and troughs, even on a low carb diet.13:22 Discussion the dismissal of real-life experiences and biases in scientific studies.- The relevance of personal experiences and the bias in funded studies are discussed.15:40 Access to life-changing health information on YouTube is being restricted.19:53 Taking stem enhance makes a significant difference in overall well-being- Stephen experimented by not taking stem enhance for six months and noticed a decline in various areas such as vision and skin vitality- After going back on stem enhance, Stephen experienced improvements in these areas, reinforcing the belief in their effectiveness21:57 Adult stem cells release exosomes containing important messages for cell function.- Exosomes contain DNA, proteins, and chemical messengers that can detect and respond to tissue conditions.- Adult stem cells play a crucial role inThank you so much for listening to my podcast. I hope you enjoyed it. Your support means the absolute world to me. And if you're enjoying the show, I've got a small favor to ask you. I'd be incredibly grateful if you would consider becoming a supporter and make a small monthly donation. Your contribution will really help to improve the show. It's a small monthly contribution. You can cancel at any time, and the link is in the show notes. Support the showAll my links in 1 easy list, including booking and personal training workout plans at LINKTREE You can now download the carnivore experience appApple direct link for apple devices Google play store direct link to app for Android Coach Stephen's Instagram Book me for coaching My growing UK carnivore YouTube channel I have set up a community that is all about eating low-carb and specifically carnivore. CLICK HERE Support my podcast from just £3 per monthBECOME A SUPPORTER Success stories Optimal Health 5 Star reviews All my facebook and other reviews are here Thanks to www.audionautix.com for any music included. Ple...
Lab Values Podcast (Nursing Podcast, normal lab values for nurses for NCLEX®) by NRSNG
Normal 5.6-7.5 % of total Hgb Indications Assess control of blood sugars over a several month time frame Diagnose Diabetes Mellitus (DM) Description Glycosylated Hemoglobin (HbA1c) is the combination of glucose and hemoglobin. When glucose is elevated in the blood the amount of glycosylated hemoglobin increases proportionally. A red blood cells lifespan is about 4 months, so you can get an idea of blood sugar control over the last several months. What would cause increased levels? Poorly controlled Diabetes Mellitus(DM) Non-Diabetic Hyperglycemia: Stress Cushing Syndrome Pheochromocytoma Corticosteroid Therapy What would cause decreased levels? Renal failure Blood loss Hemolytic anemia Sickle cell anemia
Lab Values Podcast (Nursing Podcast, normal lab values for nurses for NCLEX®) by NRSNG
Normal 2 - 20 ng/mL Indications Diagnose megaloblastic anemia Monitor effects of long-term Total Parenteral Nutrition (TPN) Identify Folate Deficiency Description Folic acid is an essential water soluble B vitamin. It is stored in the liver and is an important part of Red Blood Cell (RBC) and White Blood Cell (WBC) function, DNA replication, and cell division. What would cause increased levels? Excess folate intake What would cause decreased levels? Vitamin B12 deficiency Pernicious anemia Hemolytic anemia Celiac Disease or Crohn Disease Inflammatory Bowel Disease (IBS) Alcoholism Malnutrition
This week's episode will be focusing on hemolytic anemia. We will primarily focus on acquired forms of hemolytic anemia which include warm autoimmune hemolytic anemia (WAIHA), cold agglutinin disease (CAD), paroxysmal cold hemoglobinuria (PCH), and briefly cover a few other key differentials.
Lab Values Podcast (Nursing Podcast, normal lab values for nurses for NCLEX®) by NRSNG
Objective: Determine the significance and clinical use of iron levels in clinical practice Lab Test Name: Iron – Fe Description: Measures the amount of Fe in the bloodstream. Evaluates: Sufficient Fe level oxygen transport proper hemoglobin & RBC production Iron (Fe) is an element that is an important component of hemoglobin in red blood cells. Iron aids hemoglobin's transport of oxygen from the lungs to all the cells of the body. The storage form of iron is ferritin. Iron is transported in the blood by a protein called transferrin. Indications: Identify: Blood loss Hemochromatosis Malabsorption of iron Iron overload Type of anemia: Thalassemia Sideroblastic anemia Iron deficient anemia Normal Therapeutic Values: Normal – 50-175 μg/dL Collection: plasma separator tube What would cause increased levels: What would cause Increased Levels of Iron? Hemochromatosis Lead toxicity Iron poisoning Acute liver disease Multiple blood transfusions Hemolytic anemia Sideroblastic anemia What would cause decreased levels: What would cause Decreased Levels of Iron? Blood Loss: Gastrointestinal (GI) bleeding Heavy menstruation Chronic hematuria Hypothyroidism Iron-deficiency anemia Inadequate absorption of iron
Warm autoimmune hemolytic anemia (wAIHA) is the most common type (60-70%) of autoimmune hemolytic anemia (AIHA). In most cases, wAIHA is due an immunoglobulin G (IgG) autoantibody that binds to red blood cells (RBC), leading to hemolysis. Current recommendations for managing people with wAIHA are largely based on case series and retrospective studies involving off-label medications. Also, while there are currently no medications specifically approved to treat wAIHA, data are emerging on new therapies under investigation which may impact treatment in the future. This 60-minute CME program, hosted by Irina Murakhovskaya, MD, of the Montefiore Medical Center, Albert Einstein College of Medicine, in New York, NY and Bruno Fattizzo, MD, of the University of Milan and Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, in Milan, Italy, describes current best practices to manage patients with wAIHA.Supported by an educational grant from Janssen Biotech. For complete activity information and to obtain CME credit, please, go to www.checkrare.com
Dr. Marty Greer on Autoimmune Hemolytic Anemia Dr. Marty Greer, DVM, this year's Westminster Kennel Club and Trupanion Vet of the Year, joins host Laura Reeves to discuss Autoimmune Hemolytic Anemia in dogs. “Autoimmune hemolytic anemia is, as it sounds, an immune mediated disease,” Greer said. “But what it doesn't exactly describe is that in this particular disease, the target cells for the immune response are the circulating red blood cells. So in a patient that has autoimmune hemolytic anemia… people have it, dogs have it. Not as often in cats…. basically the body attacks its own red blood cells. “The dog goes from being pretty clinically normal, to being really profoundly sick, weak, out of breath, really, really sick. Sometimes with a fever, sometimes not, within a matter of hours to days. And when this happens, it requires an immediate diagnosis and immediate initiation of treatment. Sometimes requiring blood transfusions, 24 hour stays in the hospital, all kinds of stuff. So, it is a bad disease. “As soon as you flip the lip and you see that really pale mucus membrane color, like their gums are white or close to white. Sometimes jaundiced, just depends on how rapidly the red blood cells are being broken down and how those are being managed. The dog will look something like a dog with a splenic rupture. Or hemangiosarcoma of the spleen where they're bleeding into the abdomen. It's that same really profound anemia. Now, this tends to be most common, like I said, in middle age, to older female dogs, especially spaniels. “That being said. I've seen it probably in every breed. So, I don't think you can say, well you know, I have a corgi so it couldn't be that. I don't really think that's the case. “The other part of this is to try and determine if there's an underlying cause. It can happen spontaneously in the middle-aged and older female. It can happen after a number of vaccinations are administered at the same time, but we see a lot of it related to tick borne diseases. “(These) are thought to be triggers for this because something makes your body, say that red blood cell that's in your circulation, no, that's not my cell, that's not my protein. My immune system is going to attack it just like it would have bacteria, a virus or other foreign tissue.” Listen in to the entire episode for Dr. Greer's diagnostic and treatment recommendations. And click over to the Veterinary Voice ALBUM for a compilation of every one of Laura's in depth and practical conversations with Dr. Greer.
Alloimmune hemolytic disease of the fetus and newborn (HDFN) may occur when a pregnant woman has an antibody against an antigen on the fetal red cells inherited from the father. Many antibodies to red blood cell antigens can cause HDFN, including those from the ABO, Rh, and other blood group systems. Women can develop antibodies either through previous pregnancy or transfusion. Fatal consequences from this disorder have become rare with the appropriate use of immunoprophylaxis. However, to avoid the fatal consequences of this disorder, prompt recognition and treatment are vital. The risk for HDFN can be identified by testing the mother with an ABO group/Rh and antibody screen during the pregnancy. RhD HDFN can be prevented through passive anti-D administration to suppress the mother's immune response against the fetal RhD antigen. Some women may exhibit weak or discrepant results on RhD typing, or current results may differ from historical results. A common type of RhD variant is the weak D phenotype. Women with this phenotype have a weak expression of the RhD antigen and may present with variable RhD typing depending on the antisera or testing method used in the laboratory. Another type of RhD variant is the partial D phenotype where the RhD antigen is altered, potentially allowing an individual to form alloantibodies to the epitopes on RhD-positive red blood cells that are different than their own. In this podcast episode, we will discuss the types of HDFN, the role that partial D groups, and the presence of anti-D as it relates to its prevalence, prognosis, and management. About our Speaker: Dr. Genghis Lopez is a Senior Scientist at the Australian Red Cross Lifeblood in Brisbane, Australia. Genghis received his Ph.D. degree from Griffith University, Australia. At Lifeblood, he worked at the Platelet and Granulocyte Reference Laboratory and Red Cell Reference Laboratory and is now part of the Transfusion Science research team that investigates complex red cell blood group variants. He has published several papers in Vox Sanguinis and Transfusion journals reporting novel red cell antigens, novel blood types, and red cell antibodies including several associated with hemolytic transfusion reactions or hemolytic disease of the fetus and the newborn.
Get a free nursing lab values cheat sheet at NURSING.com/63labs What is the Lab Name for Platelets (PLT) Lab Values? Platelets What is the Lab Abbreviation for Platelets? (PLT) What is Platelets in terms of Nursing Labs? Platelets (PLT) play a role in coagulation, hemostasis, and thrombus formation. Platelets are the smallest blood cell, damaged vessels send out signals that result in platelets traveling to the area and becoming “active”. What is the Normal Range for Platelets? 100,000 – 450,000 cells/mcL What are the Indications for Platelets? Determine clotting vs bleeding disorders What would cause Increased Levels of Platelets? Malignancy Polycythemia Vera Postsplenectomy syndrome Rheumatoid Arthritis (RA) Iron-deficiency anemia Hemolytic anemia Tuberculosis Birth control What would cause Decreased Levels of Platelets? Idiopathic Thrombocytopenia (ITP) Inherited thrombocytopenia disorders: Wiskott-Aldrich Syndrome Bernard-Soulier Syndrome Zieve Syndrome Infection: Hepatitis Human Immunodeficiency Virus (HIV) Measles Sepsis Hypersplenism Hemorrhage Leukemia Lymphoma Drug Therapy: Aspirin Ibuprofen Sulfa antibiotics Hydralazine Thiazide diuretics Systemic Lupus Erythematosus (SLE) Hemolytic anemia's
Want to experience the greatest in board studying? Check out our interactive question bank podcast- the FIRST of its kind here: emrapidbombs.supercast.com. Anyone craving a hamburger? Let's talk HUS- presentation, diagnosis, and pearls and pitfalls of this classic condition. Cite this podcast as: Briggs, Blake. Episode 165: HUS: it's what's for dinner. February 13th, 2023. https://www.emboardbombs.com/podcasts/165-hus-its-whats-for-dinner. Accessed [date]
In this episode, we review the high-yield topic of Hemolytic Uremic Syndrome from the Hematology section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://anchor.fm/medbulletsstep1/message
Get a free nursing lab values cheat sheet at NURSING.com/63labs Objective: Determine the significance and clinical use of iron levels in clinical practice Lab Test Name: Iron – Fe Description: Measures the amount of Fe in the bloodstream. Evaluates: Sufficient Fe level oxygen transport proper hemoglobin & RBC production Iron (Fe) is an element that is an important component of hemoglobin in red blood cells. Iron aids hemoglobin's transport of oxygen from the lungs to all the cells of the body. The storage form of iron is ferritin. Iron is transported in the blood by a protein called transferrin. Indications: Identify: Blood loss Hemochromatosis Malabsorption of iron Iron overload Type of anemia: Thalassemia Sideroblastic anemia Iron deficient anemia Normal Therapeutic Values: Normal – 50-175 μg/dL Collection: plasma separator tube What would cause increased levels: What would cause Increased Levels of Iron? Hemochromatosis Lead toxicity Iron poisoning Acute liver disease Multiple blood transfusions Hemolytic anemia Sideroblastic anemia What would cause decreased levels: What would cause Decreased Levels of Iron? Blood Loss: Gastrointestinal (GI) bleeding Heavy menstruation Chronic hematuria Hypothyroidism Iron-deficiency anemia Inadequate absorption of iron
CME credits: 0.25 Valid until: 06-12-2023 Claim your CME credit at https://reachmd.com/programs/cme/hemolytic-disease-of-the-fetus-and-newborn-hdfn-what-pediatric-providers-need-to-know-when-managing-hemolytic-disease-in-newborns-hdn/13799/ What are the essential steps in managing hemolytic disease of the fetus and newborn (HDFN)? How soon after “the cord has been cut” does newborn care transfer from the maternal-fetal medicine specialist and ob-gyn to the pediatric team? At a recent satellite symposium of the American Academy of Pediatrics, Dr. James Bussel, Dr. Kara Markham, and Bethany Weathersby presented the latest data regarding current and emerging practice patterns and highlighted the critical need for improved understanding and multidisciplinary collaboration in the area of HDFN. Tune in to hear Dr. Markham summarize how diagnosis, care, and treatment have evolved—plus insights on how these might change the way you practice.
Lab Values Podcast (Nursing Podcast, normal lab values for nurses for NCLEX®) by NRSNG
Get a free nursing lab values cheat sheet at NURSING.com/63labs What is the Lab Name for Glycosylated Hemoglobin (HbA1c) Lab Values? Glycosylated Hemoglobin What is the Lab Abbreviation for Glycosylated Hemoglobin? HbA1c What is Glycosylated Hemoglobin in terms of Nursing Labs? Glycosylated Hemoglobin (HbA1c) is the combination of glucose and hemoglobin. When glucose is elevated in the blood the amount of glycosylated hemoglobin increases proportionally. A red blood cells lifespan is about 4 months, so you can get an idea of blood sugar control over the last several months. What is the Normal Range for Glycosylated Hemoglobin? 5.6-7.5 % of total Hgb What are the Indications for Glycosylated Hemoglobin? Assess control of blood sugars over a several month time frame Diagnose Diabetes Mellitus (DM) What would cause Increased Levels of Glycosylated Hemoglobin? Poorly controlled Diabetes Mellitus(DM) Non-Diabetic Hyperglycemia: Stress Cushing Syndrome Pheochromocytoma Corticosteroid Therapy What would cause Decreased Levels of Glycosylated Hemoglobin? Renal failure Blood loss Hemolytic anemia Sickle cell anemia
Go online to PeerView.com/MVG860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert discusses strategies that target the classical complement pathway and individualizing treatment plans for patients living with CAD. Upon completion of this activity, participants should be better able to: Describe the consequences of inhibiting complement C1s as long-term therapy for CAD, particularly on symptoms influenced predominantly by activation of the classical complement pathway (eg, chronic hemolysis, anemia, and fatigue); and Integrate classical complement pathway–targeted therapies into individualized treatment plans for CAD based on consideration of efficacy and safety data, patient-specific characteristics, and other potential prescribing considerations.
Go online to PeerView.com/MVG860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert discusses strategies that target the classical complement pathway and individualizing treatment plans for patients living with CAD. Upon completion of this activity, participants should be better able to: Describe the consequences of inhibiting complement C1s as long-term therapy for CAD, particularly on symptoms influenced predominantly by activation of the classical complement pathway (eg, chronic hemolysis, anemia, and fatigue); and Integrate classical complement pathway–targeted therapies into individualized treatment plans for CAD based on consideration of efficacy and safety data, patient-specific characteristics, and other potential prescribing considerations.
Go online to PeerView.com/MVG860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert discusses strategies that target the classical complement pathway and individualizing treatment plans for patients living with CAD. Upon completion of this activity, participants should be better able to: Describe the consequences of inhibiting complement C1s as long-term therapy for CAD, particularly on symptoms influenced predominantly by activation of the classical complement pathway (eg, chronic hemolysis, anemia, and fatigue); and Integrate classical complement pathway–targeted therapies into individualized treatment plans for CAD based on consideration of efficacy and safety data, patient-specific characteristics, and other potential prescribing considerations.
Go online to PeerView.com/MVG860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert discusses strategies that target the classical complement pathway and individualizing treatment plans for patients living with CAD. Upon completion of this activity, participants should be better able to: Describe the consequences of inhibiting complement C1s as long-term therapy for CAD, particularly on symptoms influenced predominantly by activation of the classical complement pathway (eg, chronic hemolysis, anemia, and fatigue); and Integrate classical complement pathway–targeted therapies into individualized treatment plans for CAD based on consideration of efficacy and safety data, patient-specific characteristics, and other potential prescribing considerations.
Go online to PeerView.com/MVG860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert discusses strategies that target the classical complement pathway and individualizing treatment plans for patients living with CAD. Upon completion of this activity, participants should be better able to: Describe the consequences of inhibiting complement C1s as long-term therapy for CAD, particularly on symptoms influenced predominantly by activation of the classical complement pathway (eg, chronic hemolysis, anemia, and fatigue); and Integrate classical complement pathway–targeted therapies into individualized treatment plans for CAD based on consideration of efficacy and safety data, patient-specific characteristics, and other potential prescribing considerations.
Go online to PeerView.com/MVG860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert discusses strategies that target the classical complement pathway and individualizing treatment plans for patients living with CAD. Upon completion of this activity, participants should be better able to: Describe the consequences of inhibiting complement C1s as long-term therapy for CAD, particularly on symptoms influenced predominantly by activation of the classical complement pathway (eg, chronic hemolysis, anemia, and fatigue); and Integrate classical complement pathway–targeted therapies into individualized treatment plans for CAD based on consideration of efficacy and safety data, patient-specific characteristics, and other potential prescribing considerations.
Go online to PeerView.com/MVG860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert discusses strategies that target the classical complement pathway and individualizing treatment plans for patients living with CAD. Upon completion of this activity, participants should be better able to: Describe the consequences of inhibiting complement C1s as long-term therapy for CAD, particularly on symptoms influenced predominantly by activation of the classical complement pathway (eg, chronic hemolysis, anemia, and fatigue); and Integrate classical complement pathway–targeted therapies into individualized treatment plans for CAD based on consideration of efficacy and safety data, patient-specific characteristics, and other potential prescribing considerations.
Go online to PeerView.com/MVG860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert discusses strategies that target the classical complement pathway and individualizing treatment plans for patients living with CAD. Upon completion of this activity, participants should be better able to: Describe the consequences of inhibiting complement C1s as long-term therapy for CAD, particularly on symptoms influenced predominantly by activation of the classical complement pathway (eg, chronic hemolysis, anemia, and fatigue); and Integrate classical complement pathway–targeted therapies into individualized treatment plans for CAD based on consideration of efficacy and safety data, patient-specific characteristics, and other potential prescribing considerations.
Get a free nursing lab values cheat sheet at NURSING.com/63labs What is the Lab Name for Folic Acid Lab Values? Folic Acid What is Folic Acid in terms of Nursing Labs? Folic acid is an essential water soluble B vitamin. It is stored in the liver and is an important part of Red Blood Cell (RBC) and White Blood Cell (WBC) function, DNA replication, and cell division. What is the Normal Range for Folic Acid? 2 – 20 ng/mL What are the Indications for Folic Acid? Diagnose megaloblastic anemia Monitor effects of long-term Total Parenteral Nutrition (TPN) Identify Folate Deficiency What would cause Increased Levels of Folic Acid? Excess folate intake What would cause Decreased Levels of Folic Acid? Vitamin B12 deficiency Pernicious anemia Hemolytic anemia Celiac Disease or Crohn Disease Inflammatory Bowel Disease (IBS) Alcoholism Malnutrition
In this episode, we review the high-yield topic of Autoimmune Hemolytic Anemia from the Hematology section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbulletsIn --- Send in a voice message: https://anchor.fm/medbulletsstep1/message
In this episode, we review the high-yield topic of Rh Hemolytic Disease of the Newborn from the Hematology section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbulletsIn --- Send in a voice message: https://anchor.fm/medbulletsstep1/message
One show note: The statement "Nutritional marasmus was the default code for unspecified severe nutritional marasmus SHOULD be .... was the default code for unspecified severe malnutrition". Most of you probably knew what i meant. :) Support the show
In this episode, we review the high-yield topic of Acute Hemolytic Reaction from the Heme section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets
Get a free nursing lab values cheat sheet at NURSING.com/63labs Objective: Determine the significance and clinical use of measuring Direct or Conjugated Bilirubin in clinical practice Lab Test Name: Direct or Conjugated Bilirubin Description: Bilirubin is a substance made when your body breaks down old red blood cells. This is a normal process. Bilirubin is also part of bile, which your liver makes to help digest the food you eat. A small amount of bilirubin in your blood is normal. Some bilirubin is bound to albumin in the blood. This type of bilirubin is called unconjugated, or indirect, bilirubin. In the liver, bilirubin is changed into a form that your body can get rid of. This is called conjugated bilirubin or direct bilirubin. This bilirubin travels from the liver into the small intestine. A very small amount passes into your kidneys and is excreted in your urine. This bilirubin also gives urine its distinctive yellow color and contributes to the brown color of stool. Indications: Newborns – immature liver has trouble clearing bilirubin and manifests as jaundice Investigate jaundice in adults Blockage of bile ducts- (liver or gallbladder) Detection of liver disease- particularly hepatitis Monitor progression of hepatitis Detect issues with RBC breakdown→hemolytic anemia Suspected drug toxicity- many medications are metabolized and cleared in the liver Normal Therapeutic Values: Normal – 0.0-0.2 mg/dL Collection: Plasma separator tube What would cause increased levels? Increased levels linked to: Poor liver function or hepatitis Certain medications Hemolytic anemia Pregnancy Sepsis- poor perfusion Exercise TPN ETOH What would cause decreased levels? Studies are inconclusive regarding risk or association with disease process in the presence of a decreased bilirubin level.
Guest: Kenneth J. Moise Jr., MD Host: Charles Turck, PharmD, BCPS, BCCCP Hemolytic disease of the fetus/newborn (HDFN) may be rare, but it is important to recognize and diagnose the disease and ensure appropriate patient management since the consequences in cases that go undiagnosed or are poorly managed can be devastating. To help us gain a better understanding of maternal alloimmunization and the risk for HDFN in pregnancy, Dr. Charles Turck speaks with Dr. Kenneth Moise, Director of the Comprehensive Fetal Care Center in Texas. © Janssen Pharmaceuticals, Inc. 2022 12/21 cp-272563v1
In this episode, we review the high-yield topic of Hemolytic Uremic Syndrome (HUS) from the Heme section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets
Welcome to PICU Doc On Call, A Podcast Dedicated to Current and Aspiring Intensivists. I'm Pradip Kamatand I'm Rahul Damania. We are coming to you from Children's Healthcare of Atlanta - Emory University School of Medicine. Welcome to our Episode of a 19 month old female with bloody stool, petechiae and no urine output Here's the case presented by Rahul: A 19 month old previously healthy female was brought to the pediatric emergency department for blood in her stool. Patient was at daycare the previous day where she developed a low grade fever, congestion and URI symptoms along with non-bloody-non-bilious vomiting and diarrhea. Patient had a rapid COVID test which was negative and was sent home with instructions for oral hydration. That evening, patient began having vomiting/diarrhea which worsened. She was unable to retain anything by mouth and her parents also noted blood in her stool. Due to this, she was rushed to the Emergency Department. In the ED here, she was hypertensive for age BP of 124/103 mm Hg, febrile, and ill. Specks of blood were noted on the diarrheal stool in the diaper. On her physical exam she was noted to be pale with petechiae on neck and chest. Her abdomen was soft, ND, with some hyperactive bowel sounds, and no hepatosplenomegaly. The rest of her physical examination was normal. In the ED, initial labs were significant for WBC 19, Hgb 8.8, and Platelets 34. CMP was significant for BUN of 74mg/dL and Cr of 3.5mg/dL, Na 131 mmol/L, and K of 5.5mmol/L, Ca 8.3mg/dL (corrected for albumin of 2.2g/dL), Phosphorous 8.5 AST 413, and ALT of 227, LDH > 4000. BNP was 142 and troponin negative. She was given 1 dose of CTX 50mg/kg and a 20cc/kg NS bolus. Stool PCR was sent. She was given labetalol for her hypertension, started on maintenance IV fluids and transferred to the PICU for further management. Rahul to summarize key elements from this case, this patient has: We have a 19-month old child with Diarrhea and emesis X 2 days No urine output for over 24 hours Bloody stool Petechiae on the neck and chest Anemia and thrombocytopenia All of which bring up a concern for hemolytic uremic syndrome the topic of our discussion today Let's transition into some history and physical exam components of this case. What are the key historical features in this child who presents with above? Bloody stool which alludes to an invasive diarrhea No urine output and an ill appearing state which points to a systemic inflammatory condition and end organ dysfunction. Are there some red-flag symptoms or physical exam components which you could highlight? Presence of petechiae which are physical exam features of thrombocytopenia Her pallor which is a physical exam sign of anemia Hypertension which is related to her renal dysfunction To continue with our case, the patient's labs were consistent with: Anemia Thrombocytopenia Elevated BUN and creatinine Elevated serum LDH The patient did not have hyperkalemia, or acidosis on initial presentation OK to summarize, we have a 19 month old girl with: Anemia, thrombocytopenia, and renal failure. This brings up the concern for Hemolytic uremic syndrome → Rahul Let's start with a short multiple choice question: A 2-year old boy is admitted to the PICU with acute respiratory failure secondary to pneumococcal pneumonia. On day # 3 of admission, the nurse reports the patient appears pale and has petechiae on his chest. The patient also has not had urine output for > 12 hours and appears to be fluid overloaded. Of the following the lab findings would be most consistent with the above clinical findings in the patient? A) Elevation of serum haptoglobin B) Low serum lactate dehydrogenase (LDH) C) Negative Direct Coombs test D) Peripheral smear showing schistocytes The correct answer is D-Peripheral smear showing schistocytes. Patient in the above case most likely has streptococcus pneumoniae associated hemolytic uremic syndrome commonly called as...
In this episode, Simone & Emma review the schemas of Altered Mental Status and Microangiopathic Hemolytic Anemia as they work through a case presented by Moses. Schema 1 Schema 2 Schema 3 Download CPSolvers App here Patreon website
Er du også træt af ikke at kunne bruge din fetish til at udvikle en karriere?Tænder du på smerte men ved ikke hvordan du skal lave din opstemthed om til penge?Bare rolig, din søgen er slut! For i dag skal vi tale om biologen Justin Orvel Schmidt, der har ladet sig stikke af alle stikkende insekter han nogensinde har kunne finde med et eneste mål for øjet: at finde ud af, hvilket stik der gør mest nas!Hør med når Mark fortæller om en vaskeægte smerte-conniseur og hvordan han valgte at udarbejde sin egen "objektive" smerteskala, hvor han beskriver smerte så alle kan sammenligne det med sig selv.Hvem har for eksempel ikke oplevet at blive stukket af en hveps og tænke: "Det føles lidt ligesom når min elsker nipper blidt i min øreflip"? For det har Justin Schmidt.Hvis du vil være med til at optage live med os på Discord kan du støtte os på 10er og blive en af vores kernelyttere https://bit.ly/VU10er - hvis pengene er knappe kan du også bare tjekke vores Facebookgruppe ud, vi hygger max!Du kan også tjekke vores webshop: bit.ly/vushop. Vi har T-shirts, kaffekopper og tasker! Og meget mere! Der er også en hønsetrøje!Send os water hilarious science eller stil et spørgsmål på facebook, Instagram eller vudfordret@gmail.comTak til Christian Eiming for disclaimer.Tak til Barometer-Bjarke for Gak-O-meteretHusk at være dumme
CME credits: 0.25 Valid until: 28-07-2022 Claim your CME credit at https://reachmd.com/programs/cme/hdfnnew-understandings-risk-diagnosis-and-therapeutic-approaches/12710/ Hemolytic disease of the fetus and newborn (HDFN) is a rare disease that occurs due to the incompatibility between fetal and maternal red cell antigens. HDFN can lead to both short- and long-term consequences, including potentially fatal outcomes. In order to better prevent these associated issues, the timely evaluation, recognition, and treatment of HDFN are critical. Listen in as three leading experts, Drs. Lee Shulman, Kenneth Moise, and Christopher Robinson, join together to discuss new epidemiologic evidence, the underlying pathophysiology of HDFN, health equity, and evolving management strategies you can implement to improve your clinical practice.
CME credits: 0.25 Valid until: 28-07-2022 Claim your CME credit at https://reachmd.com/programs/cme/hdfnnew-understandings-risk-diagnosis-and-therapeutic-approaches/12710/ Hemolytic disease of the fetus and newborn (HDFN) is a rare disease that occurs due to the incompatibility between fetal and maternal red cell antigens. HDFN can lead to both short- and long-term consequences, including potentially fatal outcomes. In order to better prevent these associated issues, the timely evaluation, recognition, and treatment of HDFN are critical. Listen in as three leading experts, Drs. Lee Shulman, Kenneth Moise, and Christopher Robinson, join together to discuss new epidemiologic evidence, the underlying pathophysiology of HDFN, health equity, and evolving management strategies you can implement to improve your clinical practice.
Closely related to TTP is the microangiopathic hemolytic anemia known as hemolytic uremic syndrome. While most common in children
Beyond the Pearls: Cases for Med School, Residency and Beyond (An InsideTheBoards Podcast)
About this episode Today Dr. Raj breaks down questions about periodic limb movement and the differences between normal periodic limb movement and periodic limb movement disorder as well as restless leg syndrome. The second half of the episode talks about Microangiopathic Hemolytic Anemia, ITP, TTP, DIC, and the differentiators. About Dr. Raj Dr Raj is a quadruple board certified physician and associate professor at the University of Southern California. He was a co-host on the TNT series Chasing the Cure with Ann Curry, a regular on the TV Show The Doctors for the past 7 seasons and has a weekly medical segment on ABC news Los Angeles. More from Dr. Raj www.BeyondThePearls.net The Dr. Raj Podcast Dr. Raj on Twitter Dr. Raj on Instagram Want more board review content? Crush Step 1 Step 2 Secrets Physiology by Physeo Step 1 Success Stories The InsideTheBoards Study Smarter Podcast The InsideTheBoards Podcast Study on the go for free! Download the Audio QBank by InsideTheBoards for free on iOS or Android. If you want to upgrade, you can save money on a premium subscription by customizing your plan until your test date on our website! Legal stuff and credits InsideTheBoards is not affiliated with the NBME, USMLE, COMLEX, or any professional licensing body. InsideTheBoards and its partners fully adhere to the policies on irregular conduct outlined by the aforementioned credentialing bodies. The information presented in this podcast is intended for educational purposes only and should not be construed as professional advice. This podcast is executive produced by Christopher Breitigan and Dr. Patrick Beeman. Learn more about your ad choices. Visit megaphone.fm/adchoices
A1C is an easy way to diagnose and monitor diabetes, use and limitations of A1C are discussed with Dr Rodriguez. Vaginal metformin is mentioned as an anecdote which has not been proven to work we remembered Memorial Day. Introduction: Vaginal Metformin. By Hasaney Sin, MD, and Hector Arreaza, MD.Today is May 31, 2021. There’s a saying that I came across on social media that has always spoken to me which I find relevant to our vocation. “The more I learn, the more I find out I don’t know”. So comes the joys (and challenges) of our chosen career. Case in point, have you ever heard of vaginal metformin? Neither have I, until today. There was a randomized clinical trial plan in 2013 at Assuit University in Egypt studying the effectiveness of vaginal metformin for the treatment of polycystic ovarian syndrome (PCOS). As primary care providers, we are very aware of the gastrointestinal side effects of metformin when taken PO. This sometimes prevents compliance with metformin. The study at Assuit University was to study the effectiveness of metformin when given vaginally in the effectiveness of treating PCOS, while also decreasing the undesirable side effects of metformin when given PO in hopes of also ultimately improving adherence. Unfortunately, the study was planned to be finished in 2014, but no results have been published thus far[1]. Stay tuned in case there is any update.Arreaza: I had to do a search because I was very curious too. There is at least one occurrence when vaginal metformin was mentioned, at least in English. It was in an online forum where a doctor recommended vaginal metformin for PCOS to a patient. This has not been evaluated or approved by any organization, so I would not recommend it. You know what would be great? Metformin patches! There you have a business idea guys: The Metfo-patch®. This is Rio Bravo qWeek, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California. Our program is affiliated with UCLA, and it’s sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. Introduction: Memorial Day. Written by Valerie Civelli, MD, read by Steven Saito, MD, and Hector Arreaza, MDWhat is Memorial Day? Memorial Day is an American holiday at the end of May to honor the men and women who died while serving in the US military. It has great historical meaning to Americans. It originated from the Civil War which claimed more lives than any other conflict in US history. Civil war ended in 1865. A fun fact to know, is that Memorial Day, was originally called “Decoration Day”. It was 3-years after the Civil war ended, May 5, 1868, that “Decoration Day” was declared as a time for the nation to decorate the graves of those lost in war. Graves were adorned with flowers and their lives celebrated. Maj. Gen. John A. Logan then declared that “Decoration Day” should be observed on May 30th. It is believed that this date was chosen because flowers would be in full bloom across the country. The “birthplace” of “Memorial Day” was recognized as coming from Waterloo, New York, because Waterloo was the first to use this term to expand honor and recognition of all US fallen soldiers of war from the Civil War and from World War I. In 1971, “Memorial Day” was officially declared a national federal holiday: The National Moment of Remembrance encourages all Americans to pause wherever they are at 3:00 p.m. local time on Memorial Day for a minute of silence, to remember and honor those who have died in service to the nation. If you value your freedom wherever you are, this Memorial Day at 3:00 p.m., pause for a minute to recognize all of our military men and women, both past and present who served and continue to serve our country. We honor every soldier who lost his or her life in any war against America. You are the reason for our freedoms. You gave the ultimate sacrifice, and we do not take this for granted. To all military members who have died at war, we appreciate the privileges we have today because of you. We honor the costly price at which it came. We remember you. We honor you. We sincerely thank you. Happy Memorial Day everyone! ___________________________A1C.By Hector Arreaza, MD, and Yodaisy Rodriguez, MD. Definition. Glycated hemoglobin (glycohemoglobin, hemoglobin A1c, or just A1c) is a form of hemoglobin that is chemically linked to a sugar. Glucose spontaneously bind with hemoglobin, when present in the bloodstream of humans.A1C refers to the percentage of glycosylation of the hemoglobin A1C chain and correlates with the average blood glucose levels over the previous 2-3 months from the slow turnover of red blood cells in the body. A RBC lives 120 days.History of A1C. Huisman and Meyering separated glycohemglobin for the first time in 1958. A1c for monitoring the degree of control of glucose metabolism in diabetic patients was proposed in 1976 by Anthony Cerami, Ronald Koenig and coworkers.A1C was first included in the ADA guidelines as a diagnostic test for diabetes in 2010. Prior to that random glucose or fasting plasma glucose were used for diagnosis.For diagnosis of diabetes, A1C testing should be done by a technique certified by the National Glycohemoglobin Standardization Program and consistent with the Diabetes Control and Complications Trial reference assay.A1C levels. A1C 6.5% is diabetes.Of note, other criteria for diagnosing diabetes: Fasting plasma glucose >126 mg/dL, 2-hour plasma glucose > 200, random glucose >200 plus classic symptoms.In patients with prediabetes, A1C should be tested yearly.The American Diabetes Association (ADA) has recommended glycated hemoglobin testing (HbA1c) twice a year for patients with stable glycemia, and quarterly for patients with poor glucose control. Use ADA guidelines to assess targets.Point-of-care A1C (POC A1C): POC is not recommended for screening or diagnosis but it is good for monitoring.A1C limitations.There are some limitations to A1C testing, and an incomplete correlation between A1C level and average glucose level in certain individuals.Nonglycemic Factors That May Interfere with A1C MeasurementFalsely lower A1C: Acute blood loss, Chronic liver disease, Hemolytic anemias, Patients receiving antiretroviral treatment for human immunodeficiency virus, Pregnancy, Vitamins E and C. Patients being treated for iron, B12 or folate deficiency, EPO, chronic hemolysis (thalassemia). Lower or elevate A1C: Hemoglobinopathies or hemoglobin variants, Malnutrition Falsely elevate A1C: Aplastic anemias, Hyperbilirubinemia, Hypertriglyceridemia, Iron deficiency anemias, Renal failure, Splenectomy.For example, when RBCs have a short life, like in acute bleeding, the A1C is falsely low. On the other hand, when RBCs live longer (history of splenectomy and aplastic anemias) the A1C is falsely elevated. It’s a good idea to do CBC with A1C.Ethnic groups: Hemoglobinopathies or hemoglobin variants can change A1C levels and may be more prevalent among certain racial and ethnic groups. A1C tends to be higher in some races/ethnic groups: AA, Hispanic-Americans, Asian-Americans.Other A1C limitations: It gives you an average, patient may be experiencing hypoglycemia alternated with hyperglycemia and result in normal A1C. Screening for diabetes.ADA: Screen for diabetes or prediabetes all asymptomatic adults, according to the ADA, who have overweight or obesity with one or more risk factor (first degree relative with diabetes, high risk race or ethnic group, history of CVD, hypertension, dyslipidemia, PCOS, physical inactivity, severe obesity, acanthosis nigricans), patients with prediabetes (every year), women with GDM (every 3 years), all other patients after 45 years of age. If results are normal, test every 3 years, patients with HIV.USPSTF: Adults aged 40 to 70 years who are overweight or obese. The USPSTF recommends screening for abnormal blood glucose as part of cardiovascular risk assessment in adults aged 40 to 70 years who are overweight or obese. (Draft: Asymptomatic adults ages 35 to 70 years who are overweight or obese) This is a Grade B recommendation. Clinicians should offer or refer patients with abnormal blood glucose to intensive behavioral counseling interventions to promote a healthful diet and physical activity. The USPSTF recommends screening for gestational diabetes mellitus (GDM) in asymptomatic pregnant women after 24 weeks of gestation. This is a Grade B recommendation.Grade I recommendation (insufficient evidence): Asymptomatic pregnant women, Before 24 Weeks of Gestation. The USPSTF concludes that the current evidence is insufficient to screen for GDM in asymptomatic pregnant women before 24 weeks of gestation.A1C Targets.A1C goals can range from 6.5% to 8%. Target is individualized based on life expectancy, disease duration, presence of complications, CVD risk factors, comorbid conditions and risks for severe hypoglycemia. Sometimes your goal can be independent of A1C, for example, your goal can be to avoid complications. As a fun fact, A1C is not used in veterinary medicine.Conclusion.By Hector Arreaza, MD. Now we conclude our episode number 54 “A1C”, three characters that may not mean much for most people but for patients with diabetes, it is a very important number to remember. Remember to check the A1C in all your patients with poor control of diabetes every 3 months, or every 6 months in patients with good control. A1C has its limitations but it certainly is the best way to assess your patients’ glycemic control. We started this episode by giving you a random report about vaginal metformin, the study was unfinished, and we also reminded you of the importance of remembering our heroes during Memorial Day. Even without trying, every night you go to bed being a little wiser.Thanks for listening to Rio Bravo qWeek. If you have any feedback about this podcast, contact us by email RBresidency@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. This podcast was created with educational purposes only. Visit your primary care physician for additional medical advice. This week we thank Hector Arreaza, Hasaney Sin, Valerie Civelli, Yodaisy Rodriguez, and Steven Saito. Audio edition: Suraj Amrutia. See you next week!References:Vaginal Administration of Metformin in PCOS Patients, U.S. National Library of Medicine, Clinical Trials.Gov, https://clinicaltrials.gov/ct2/show/study/NCT02026869. Office of Public and Intergovernmental Affairs, U.S. Department of Veteran Affairs, https://www.va.gov/opa/speceven/memday/history.asp, accessed on May 26, 2021. Pippitt K, Li M, Gurgle HE. Diabetes Mellitus: Screening and Diagnosis. Am Fam Physician. 2016 Jan 15;93(2):103-9. Erratum in: Am Fam Physician. 2016 Oct 1;94(7):533. PMID: 26926406. https://www.aafp.org/afp/2016/0115/p103.html. Standards of Medical Care in Diabetes – 2021, Diabetes Care, January 1, 2021, vol 44 issue supplement 1, https://care.diabetesjournals.org/content/diacare/suppl/2020/12/09/44.Supplement_1.DC1/DC_44_S1_final_copyright_stamped.pdf.
Sickle Cell Anemia Genetic Pattern Autosomal recessive Homozygote inheritance of Hemoglobin S (HbS) Predominantly seen in the African American population Oxygenated HbS does not dissolve well and forms a gel that distorts the shape of the RBC into a sickle. This makes the cells “sticky” and less flexible leading to clogging of small blood vessels. […] The post PAER S2 077 Hemolytic Anemias appeared first on Physician Assistant Exam Review.
This podcast presents an approach to hemolytic anemia in children. In it, the listener will learn to define hemolytic anemia, explain the pathophysiology, describe the clinical manifestations, list relevant investigations and outline the management of a child with hemolytic anemia. This podcast was created by Prachi Shah, a medical student at the University of Alberta, in collaboration with Dr. Aisha Bruce, a pediatric hematologist at the Stollery Children’s Hospital in Edmonton.
Diagnosis and treatment of acquired hemolytic anemia can be challenging. In this How I Treat series, edited by Mario Cazzola, clinical experts discuss their approaches to the treatment of patients with 4 different classes of acquired hemolytic anemia.
Noreen Walsh discovered art therapy, 30 years after experiencing a stroke due to complications from Hemolytic–uremic syndrome (HUS) at 18 months old. The post 120. Art Therapy For Stroke Recovery – Noreen Walsh appeared first on Recovery After Stroke.
Noreen Walsh discovered art therapy, 30 years after experiencing a stroke due to complications from Hemolytic–uremic syndrome (HUS) at 18 months old. The post 120. Art Therapy For Stroke Recovery – Noreen Walsh appeared first on Recovery After Stroke.
CME credits: 0.25 Valid until: 30-10-2021 Claim your CME credit at https://reachmd.com/programs/cme/hemolytic-disease-fetus-and-newborn-cutting-edge-strategies-diagnosis-and-management/11954/ Hemolytic disease of the fetus and newborn (HDFN) is a rare condition with an estimated 3-80 cases per 100,000 pregnancies in the US every year. HDFN occurs when maternal red blood cells or blood group antibodies cross the placenta during pregnancy and cause fetal red cell destruction. The physiologic consequences of severe anemia in the fetus can lead to edema, ascites, hydrops, heart failure, and even death. This activity provides strategies for the diagnosis and management of HDFN, including available algorithms for diagnosis and follow-up therapy.
CME credits: 0.25 Valid until: 30-10-2021 Claim your CME credit at https://reachmd.com/programs/cme/hemolytic-disease-fetus-and-newborn-cutting-edge-strategies-diagnosis-and-management/11954/ Hemolytic disease of the fetus and newborn (HDFN) is a rare condition with an estimated 3-80 cases per 100,000 pregnancies in the US every year. HDFN occurs when maternal red blood cells or blood group antibodies cross the placenta during pregnancy and cause fetal red cell destruction. The physiologic consequences of severe anemia in the fetus can lead to edema, ascites, hydrops, heart failure, and even death. This activity provides strategies for the diagnosis and management of HDFN, including available algorithms for diagnosis and follow-up therapy.
This short but sweet episode takes you through the approach to understanding warm and cold hemolytic anemia, as well as what to ask on history, and appropriate investigations. Written by: Dr. Adam Suleman (Internal Medicine ResidentReviewed by: Dr. Eric Tseng (Hematology) & Dr. Yuna Lee (Internal Medicine)
Join Yvonne Brandenburg, RVT, VTS SAIM and Jordan Porter RVT, LVT, VTS SAIM as we talk about: Part 2 of our IMHA and IMTP episodes. This week we are diving into diagnostics, treatment, and our favorite; CLIENT COMMUNICATION! We discuss what to look for when managing these patients, and how to prepare clients for managing these pets at home. For our 1 year episode. Must be in by October 11th! We’d love to hear from you! Leave us a message at 925-579-1216 and we’ll play you on the show! Sunday Oct 11th at 8:30a PST: Platelet Count Webinar Monday October 12th 10a PST/ 12p CST Royal Canin Webinar 1 hour RACE approved webinar Upping Your Tech Game: Being A Rock Star Tech register at: http://imfpp.org/rcregistration For a list of current webinars go to http://imfpp.org/webinar Vet Tech Appreciation Week Poster: got to https://www.internalmedicineforvettechs.com/vet-tech-appreciation-week.html and download a copy to share! Question of the Week What is your experience with IMHA/IMTP or Evans? Leave a comment at https://imfpp.org/episode52 Resources We Mentioned in the Show Bistner, S. I., Ford, R. B., & Raffe, M. R. (2000). Kirk and Bistner's Handbook of Veterinary Procedures and Emergency Treatment (7th ed.). Philadelphia, Pennsylvania: W. B. Saunders Company. Brandenburg, Y. (2017). Evans Syndrome: A Technician's Role. ACVIM. National Harbor: American College of Veterinary Internal Medicine. For a copy go to https://imfpp.org/ACVIM2017 Brooks, M. B., & Catalfamo, J. L. (2010). Chapter 189 Immune-Mediated Thrombocytopenia, von Willebrand Disease, and Platelet Disorders. In S. J. Ettinger, Textbook of Veterinary Internal Medicine Disease of the Dog and the Cat (7th ed., Vol. 1, pp. 772-783). St. Louis, Missouri: Sounders Elsevier. e-Clin Path. Hematology » Anemia » Mechanisms. (2020, September 27). Retrieved from https://eclinpath.com/hematology/anemia/mechanisms-of-anemia/ Garcia, J., & South-Bodiford, R. (2012). Chapter 7 Hematology. In L. Merrill, Small Animal Internal Medicine for Veterinary Technicians and Nurses (pp. 161-192). Danvers, Massachusetts: Blackwell Publishing. Immune Mediated Hemolytic Anemia in Dogs IMHA. (2017). Retrieved February 10, 2020, from Facebook: https://www.facebook.com/groups/6228146980/ Immune Mediated Hemolytic Anemia in Dogs (IMHA). (2017, 12 6). Retrieved from Facebook: https://www.facebook.com/groups/6228146980 Immune-Mediated Thrombocytopenia (IMT)~Canine Immune Disorders~Blood Clots. (2017, 12 6). Retrieved from Facebook: https://www.facebook.com/groups/ImmMediatedThrombocytopeniaCanineImmuneDisorders/ Internal Medicine For Vet Techs. (2020, February 10). Retrieved from Technician Treasure Trove: https://imfpp.org/treasuretrove Johnson, V., & Dow, S. (2014). Chapter 60 Management of Immune-Mediated Hemolytic Anemia in Dogs. In J. D. Bongura, & D. C. Twedt, Kirk's Current Veterinary Therapy (XV ed., pp. 275-279). St. Louis, Missouri: Elsevier. Mackin, A. (2016). Immunosuppressive Therapy in Dogs and Cats: Recent Drug Development. 2016 ACVIM Forum (pp. 1113-1117). Denver: American College of Veterinary Internal Medicine. Mitchell, K., & Kruth, S. (2010). Chapter 188 Immune-Mediated Hemolytic Anemia and Other Regenerative Anemias. In S. J. Ettinger, Textbook of Veterinary Internal Medicine Diseases of the Dog and the Ca (7th ed., Vol. 1, pp. 761-772). St. Louis, Missouri: Saunders Elsevier. Mitchell, K., & Kruth, S. (2010). Chapter 188 Immune-Mediated Hemolytic Anemia and Other Regenerative Anemias. In S. J. Ettinger, Textbook of Veterinary Internal Medicine Diseases of the Dog and the Ca (7th ed., Vol. 1, pp. 761-772). St. Louis, Missouri: Saunders Elsevier. Nakamura, R. K., Tompkins, E., & Bianco, D. (2012, January 25). Therapeutic Options For Immune-Mediated Thrombocytopenia. Journal of Veterinary Emergency and Critical Care, 22(1), 59-72. doi:10.1111/j.1476-4431.2011.00705.x Neel, J. A., Birkenheuer, A. J., & Grindem, C. B. (2014). Chapter 61 Thrombocytopenia. In J. D. Bonagura, & D. C. Twedt, Kirk's Current Veterinary Therapy (Vol. XV, pp. 280-286). St. Louis, Missouri: Elsevier. Norton, A., & Roberts, I. (2005). Management of Evans Syndrome. British Journal of Haematology, 125-137. doi:10.1111/j.1365-2141.2005.05809.x Pharmacology Laboratory. (2014). Retrieved from Mississippi State University College of Veterinary Medicine: http://www.cvm.msstate.edu/animal-health-center/pharmacodynamic-laboratory Plumb, D. (2011). Plumb's Veterinary Drug Handbook (7th ed.). Stockholm, Wisconsin: Wiley-Blackwell. Thomason, J. D., & Calvert, C. A. (2012). Chapter 5 Thrombotic Disorders in Small Animal Medicine. In L. Merrill, Small Animal Internal Medicine for Veterinary Technicians and Nurses (pp. 127-135). Danvers, Massachusetts: Blackwell Publishing. West, L. D., & Hart, J. R. (2014). Treatment of Idiopathic Immune-Mediated Hemolytic Anemia with Mycophenolate Mofetil in Five Dogs. Journal of Veterinary Emergency and Critical Care, 24(2), 226-231. doi:10.1111/vec.12121 Listen to episodes 50 Immune System: When the Body Attacks 21 Hematology Kickoff: Back to Basics 22 RBC’s Anemia to Polycythemia 23 Coag’s Balancing Hemostasis Website references: https://www.internalmedicineforpetparents.com/imha.html https://www.internalmedicineforpetparents.com/imtp.html Thanks so much for tuning in. Join us again next week for another episode! Want to earn some RACE approved CE credits for listening to the podcast? You can earn between 0.5-1.0 hour of RACE approved CE credit for each podcast episode you listen to. Join the Internal Medicine For Vet Techs Membership to earn and keep track of your continuing education hours as you get your learn on! Join now! http://internalmedicineforvettechsmembership.com/ Get Access to the Membership Site for your RACE approved CE certificates Sign up at https://internalmedicineforvettechsmembership.com Get Access to the Technician Treasure Trove Sign up at https://imfpp.org/treasuretrove Thanks for listening! – Yvonne and Jordan
Join Yvonne Brandenburg, RVT, VTS SAIM and Jordan Porter RVT, LVT, VTS SAIM as we talk about: We are scraping the surface when discussing immune mediated hemolytic anemia and immune mediated thrombocytopenia. We are discussing common symptoms we see when these patients present. For our 1 year episode. Must be in by October 11th! We’d love to hear from you! Leave us a message at 925-579-1216 and we’ll play you on the show! Sunday Oct 11th at 8:30a PST: Platelet Count Webinar Monday October 12th 10a PST/ 12p CST Royal Canin Webinar 1 hour RACE approved webinar Upping Your Tech Game: Being A Rock Star Tech register at: http://imfpp.org/rcregistration For a list of current webinars go to http://imfpp.org/webinar Vet Tech Appreciation Week Poster: got to https://www.internalmedicineforvettechs.com/vet-tech-appreciation-week.html and download a copy to share! Question of the Week What do you like or dislike about IMHA or IMTP, or have you never had the pleasure of managing one of these cases? Leave a comment at https://imfpp.org/episode51 Resources We Mentioned in the Show Bistner, S. I., Ford, R. B., & Raffe, M. R. (2000). Kirk and Bistner's Handbook of Veterinary Procedures and Emergency Treatment (7th ed.). Philadelphia, Pennsylvania: W. B. Saunders Company. Brandenburg, Y. (2017). Evans Syndrome: A Technician's Role. ACVIM. National Harbor: American College of Veterinary Internal Medicine. For a copy go to https://imfpp.org/ACVIM2017 Brooks, M. B., & Catalfamo, J. L. (2010). Chapter 189 Immune-Mediated Thrombocytopenia, von Willebrand Disease, and Platelet Disorders. In S. J. Ettinger, Textbook of Veterinary Internal Medicine Disease of the Dog and the Cat (7th ed., Vol. 1, pp. 772-783). St. Louis, Missouri: Sounders Elsevier. e-Clin Path. Hematology » Anemia » Mechanisms. (2020, September 27). Retrieved from https://eclinpath.com/hematology/anemia/mechanisms-of-anemia/ Garcia, J., & South-Bodiford, R. (2012). Chapter 7 Hematology. In L. Merrill, Small Animal Internal Medicine for Veterinary Technicians and Nurses (pp. 161-192). Danvers, Massachusetts: Blackwell Publishing. Immune Mediated Hemolytic Anemia in Dogs IMHA. (2017). Retrieved February 10, 2020, from Facebook: https://www.facebook.com/groups/6228146980/ Immune Mediated Hemolytic Anemia in Dogs (IMHA). (2017, 12 6). Retrieved from Facebook: https://www.facebook.com/groups/6228146980 Immune-Mediated Thrombocytopenia (IMT)~Canine Immune Disorders~Blood Clots. (2017, 12 6). Retrieved from Facebook: https://www.facebook.com/groups/ImmMediatedThrombocytopeniaCanineImmuneDisorders/ Internal Medicine For Vet Techs. (2020, February 10). Retrieved from Technician Treasure Trove: https://imfpp.org/treasuretrove Johnson, V., & Dow, S. (2014). Chapter 60 Management of Immune-Mediated Hemolytic Anemia in Dogs. In J. D. Bongura, & D. C. Twedt, Kirk's Current Veterinary Therapy (XV ed., pp. 275-279). St. Louis, Missouri: Elsevier. Mackin, A. (2016). Immunosuppressive Therapy in Dogs and Cats: Recent Drug Development. 2016 ACVIM Forum (pp. 1113-1117). Denver: American College of Veterinary Internal Medicine. Mitchell, K., & Kruth, S. (2010). Chapter 188 Immune-Mediated Hemolytic Anemia and Other Regenerative Anemias. In S. J. Ettinger, Textbook of Veterinary Internal Medicine Diseases of the Dog and the Ca (7th ed., Vol. 1, pp. 761-772). St. Louis, Missouri: Saunders Elsevier. Mitchell, K., & Kruth, S. (2010). Chapter 188 Immune-Mediated Hemolytic Anemia and Other Regenerative Anemias. In S. J. Ettinger, Textbook of Veterinary Internal Medicine Diseases of the Dog and the Ca (7th ed., Vol. 1, pp. 761-772). St. Louis, Missouri: Saunders Elsevier. Nakamura, R. K., Tompkins, E., & Bianco, D. (2012, January 25). Therapeutic Options For Immune-Mediated Thrombocytopenia. Journal of Veterinary Emergency and Critical Care, 22(1), 59-72. doi:10.1111/j.1476-4431.2011.00705.x Neel, J. A., Birkenheuer, A. J., & Grindem, C. B. (2014). Chapter 61 Thrombocytopenia. In J. D. Bonagura, & D. C. Twedt, Kirk's Current Veterinary Therapy (Vol. XV, pp. 280-286). St. Louis, Missouri: Elsevier. Norton, A., & Roberts, I. (2005). Management of Evans Syndrome. British Journal of Haematology, 125-137. doi:10.1111/j.1365-2141.2005.05809.x Pharmacology Laboratory. (2014). Retrieved from Mississippi State University College of Veterinary Medicine: http://www.cvm.msstate.edu/animal-health-center/pharmacodynamic-laboratory Plumb, D. (2011). Plumb's Veterinary Drug Handbook (7th ed.). Stockholm, Wisconsin: Wiley-Blackwell. Thomason, J. D., & Calvert, C. A. (2012). Chapter 5 Thrombotic Disorders in Small Animal Medicine. In L. Merrill, Small Animal Internal Medicine for Veterinary Technicians and Nurses (pp. 127-135). Danvers, Massachusetts: Blackwell Publishing. West, L. D., & Hart, J. R. (2014). Treatment of Idiopathic Immune-Mediated Hemolytic Anemia with Mycophenolate Mofetil in Five Dogs. Journal of Veterinary Emergency and Critical Care, 24(2), 226-231. doi:10.1111/vec.12121 Listen to episodes 50 Immune System: When the Body Attacks 21 Hematology Kickoff: Back to Basics 22 RBC’s Anemia to Polycythemia 23 Coag’s Balancing Hemostasis Website references: https://www.internalmedicineforpetparents.com/imha.html https://www.internalmedicineforpetparents.com/imtp.html Thanks so much for tuning in. Join us again next week for another episode! Want to earn some RACE approved CE credits for listening to the podcast? You can earn between 0.5-1.0 hour of RACE approved CE credit for each podcast episode you listen to. Join the Internal Medicine For Vet Techs Membership to earn and keep track of your continuing education hours as you get your learn on! Join now! http://internalmedicineforvettechsmembership.com/ Get Access to the Membership Site for your RACE approved CE certificates Sign up at https://internalmedicineforvettechsmembership.com Get Access to the Technician Treasure Trove Sign up at https://imfpp.org/treasuretrove Thanks for listening! – Yvonne and Jordan
Hemolytic anemias are a group of disorders where red blood cell survival is reduced either continuously or episodically. Because a patient's bone marrow has the ability to increase erythroid production up to eighteen times in response to reduced red blood cell survival, a patient will only present with anemia when the patient's bone marrow production is outstripped. This will occur when red blood cell survival is extremely short or when the bone marrow's ability to compensate is impaired. Hemolytic disorders are generally classified based on whether the defect is intrinsic to the red blood cell or due to some external factor. Certain laboratory features are common to all hemolytic anemias. To take just a few examples, Haptoglobin, a normal plasma protein that binds and clears free hemoglobin released into plasma, may be depressed in hemolytic disorders. Haptoglobin levels, though, are influenced by many factors and may not be a reliable indicator of hemolysis – particularly in end-stage liver disease. When intravascular hemolysis occurs, transient hemoglobinemia ensues. Here, hemoglobin is filtered through the renal glomerulus and is usually reabsorbed by tubular cells. Hemoglobinuria will be present only when the patient's capacity for reabsorption of hemoglobin by renal tubular cells is exceeded, In the absence of hemoglobinuria, evidence for prior intravascular hemolysis is the presence of hemosiderin in shed tubular cells. With severe intravascular hemolysis, hemoglobinemia and methemsalbuminemia may be present. Hemolysis increases indirect bilirubin levels and the total bilirubin may rise to 4mg/dL or more. Bilirubin levels higher than this may indicate some degree of hepatic dysfunction. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app
? Eculizumab, complement inhibitor in severe COVID19 | Dr RR Baliga's 'Got Knowledge Doc?' Podkasts for Physicians | Will Complement Inhibition be the New Target in Treating COVID-19 Related Systemic Thrombosis? | Circulation https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.120.047419#.XqjUc7YNhYU.twitter Not Medical Advice or Opinion
Pathologystudent.com - Are hemolytic-uremic syndrome & thrombotic thrombocytopenic purpura related?
Hello listeners! Welcome to our 30th episode featuring our very close friend Taylor Sanders! This week we decided to start our episode off with a recap of our summer. We then we share some of our favorite Halloween memories to get ready for spooky season. And to finish off the episode, Taylor was kind enough to share her story about her becoming diagnosed with HUS (Hemolytic Uremic Syndrome), to help bring awareness to everyone about his rare condition.Thanks for listening!If you enjoy our content and want to show your support, click the link! paypal.me/nu2upodcastPlease follow our social media pages!Twitter: @Nu2u_PodcastInstagram: @Nu2u_PodcastFacebook: @Nu2u.Podcast
This podcast was developed by Dr. Magdalena Riedl, a second year resident at The Hospital for Sick Children and the University of Toronto, and Dr. Chia Wei Teoh, staff nephrologist at The Hospital for Sick Children. This podcast will address the etiology, pathophysiology, presentation, diagnosis and management of hemolytic uremic syndrome (HUS).
Session 17 Dr. Karen Shackelford from BoardVitals is joining me once again for another round of discussion. This week, we tackle a certain kind of pediatric illness. [01:11] Question of the Week: A 10-year-old male patient is evaluated for abdominal pain he has had for two days. He has a rash on his buttocks and thighs. It appeared about three days ago. He's also complaining of some pain in his ankles and knees. His past medical history is unremarkable. But he was seen in the clinic two weeks ago with symptoms of an upper respiratory infection. On physical exam, his abdomen has standard palpation. 01:42 He has multiple palpable purpuras on his buttocks and upper thighs. 01:50 His ankle is swollen and tender on the right. There's no warrant for eczema. His knee is tender. But otherwise, his exam was unremarkable. His laboratory study is showing a normal CBC. On urine 02:09, he has microhematuria. What is the most likely diagnosis? (A) IgA vasculitis (formerly Purpura) (B) Hemolytic uremic syndrome (C) Kawasaki disease (D) Acute post-streptococcal glomerulonephritis [03:40] Thought Process The correct answer here is IgA vasculitis. The palpable purpura on the buttocks and lower extremities is one of the criteria you have to have for purpura, without thrombocytopenia. The other symptoms this patient has, where you could have one or all of these other symptoms, including polyarthralgia, usually in the hip, ankle, and/or knee joints. GI symptoms include abdominal pain, nausea, vomiting, 05:26 or intussusception. Thi has renal involvement, without thrombocytopenia or coagulopathy. These are the two big things. As mentioned, the CBC was normal and he did have the proliferative glomerulonephritis, which occurs with the IgA deposition in the glomeruli. Leukocytoclastic vasculitis is characterized by leukocytes. Neutrophils or monocytes are around the small vessels – the arterioles and venules. There's IgA deposition. There can be IgG or IgM. There is complement C through a deposition. This is what you would see in a biopsy. The lesions are generally in the GI tract or in the skin (which are typically the ones that are biopsied). But if the patient does develop the glomerulonephritis, renal biopsy will show that. That doesn't develop in every case. The disorder is self-limited so treatment-supportive. It's an immune complex seen usually after an upper respiratory infection. In one case series, it has been associated with the MMR vaccine, although this might not have been held up in the later studies. This is also common between the ages of 3 and 11. One of the diagnostic criteria is that the patient has to be under 20. [07:35] Going Through Other Answer Choices In hemolytic uremic syndrome, you can have 07:41 purpura, although they're non-palpable and they're palpable in an 07:49 purpura. That occurs in hemolytic uremic syndrome due to thrombocytopenia. And this patient has a normal CBC. Hemolytic uremic syndrome is usually associated with E.coli infection in the previous case of diarrhea. But there's no history of that in the patient. There is abdominal pain but the rash is not limited to the lower extremities and buttocks. That is characteristic of HSP IgA vasculitis. Kawasaki disease usually occurs in children under the age of 4. The case will usually present a child of Asian descent. It's more prevalent in Japanese children who are at a high risk of IVIG resistance. They will generally have conjunctivitis and fever for more than 5 days. They have that strawberry tongue. The skin manifestations are non-palpable purpura, but there are periungual desquamation and hand-and-foot erythema. Acute post-streptococcal glomerulonephritis can present with hematuria. It can occur after a skin infection or a pharyngeal infection. That was meant to be with a rash. Maybe someone will consider this because there's a rash involved. As group-A beta-hemolytic strep, this patient had a previous upper respiratory infection which could potentially have been caused by strep. But arthralgia isn't common. Abdominal pain isn't common. And the purpura also not associated with acute post-streptococcal glomerulonephritis. [11:10] BoardVitals If you're looking for a QBank in preparing for your board, check out BoardVitals. They have over 1700 questions for Step 1 and over 1500 questions for Level 1 with detailed explanations behind every question and every answer. Use the promo code BOARDROUNDS to save 15% off. Links: BoardVitals (promo code BOARDROUNDS to save 15% off)
Podcast summary of articles from the April 2019 edition of the Journal of Emergency Medicine from the American Academy of Emergency Medicine. Topics include optic nerve sheath diameter for increased ICP, neck trauma management, naloxone prescriptions, atypical hemolytic uremic syndrome, babesiosis and extended board review on endovascular treatment for stroke. Guest speaker is Dr. Salim Rezaie.
Join Dan (@drusyniak) &Howard (@heshiegreshie) as they speak with Dr. Rick Vetter about all things brown recluse, why you should always inspect your packages very, very carefully, and why Howard will never move to Kansas. Delicious Links The USPS should be known as “The Fearless” . . . Arachnids submitted as suspected brown recluse spiders. . . And brown recluse spiders live where they do. How to Identify and Misidentify a Brown Recluse Spider. Step #1 - Check the Map. . . Step #999999 - if you can count the eyes, YOU ARE TOO CLOSE. A reason for this family to play the lottery . . . An infestation of 2,055 brown recluse spiders and no envenomations in a Kansas home. . . The Myth of the Brown Recluse - Fact, Fear, and Loathing by Dr. Vetter Don't forget that systemic symptoms can occur as well. Hemolytic anemia following a presumptive brown recluse spider bite. NOT RECLUSE - a mnemonic device to avoid false diagnoses of brown recluse spider bites. Dan is happy to remind NYC of mistakes we've made . . . Cutaneous Anthrax Infection initially diagnosed as a brown recluse spider bite. Maratus volans, or the peacock spider, is a species in the jumping spider family with a very interesting mating dance. . . To be an Explorer. A special meal with tempura tarantula in ponzu sauce. “Eight legs. Two fangs. And an attitude.” Special Thanks Thank you for your continued support. As always, we are looking for feedback - comments, questions, suggestions, recipes, etc. Let us know. Reach us at @toxandhound. We want to hear from you! Thank you to our house band Pretty Simple Duo (@prettysimpleduo), our announcer Josh Shelov (@shelovj), and Reverend Matt Winston of Witness Protection Products. Ad at 26:15 . . . Peacock Spider Maratus volans by Jurgen Otto. Special thanks to Ice T, Dick Wolf and the cast and crew of Law & Order: SVU for the years of amazing television. Made with love and respect. Interested in #FOAMtox? Like this podcast? Take a gander at The Tox and The Hound. It's like a podcast, but for your eyes. Listen on iTunes or Spotify! Earholes happy? Rate and review! Show the love!
In this episode you'll hear about the what exactly is hemolytic anemia, signs, symptoms and treatment for those of us with lupus. So you know what to do. --- Send in a voice message: https://anchor.fm/susan-hendrix/message
Sharmin, Arsalan, Rabih and Reza share an approach to hemolytic anemia.
Thank you for joining us for our 2nd Cabral HouseCall of the weekend! I’m looking forward to sharing with you some of our community’s questions that have come in over the past few weeks… Let’s get started! Eliana: Hello, I would first like to say that I absolutely love your Podcasts and everything you have taught me thus far! I am a 21 year old personal trainer who is extremely interested in natural health and this podcast has changed my world! I have been struggling with a hiatal hernia for years. It feels like something is pressed up against my diaphragm or sometimes my left rib cage (it switches between those 2 places so sometimes I wonder if my diaphragm is out rather than it being a hiatal hernia). I have received chiropractic treatment for this and while the manual adjustment of pushing it back into place does help, it does not last. My mom, grandma, and twin sister also struggle with this. I had lymes disease 3-4 years ago (so did mom and sister) and was treated with a combination of homeopathy, Chinese herbs and glandulars by a lymes specialist in Maine. Also had H pylori and Epstein bar and was treated for those coinfections as well. Since then I feel great, had a feeling of relapse a year ago and cut out all food sensitivities. I feel great again but my hiatal hernia comes and goes in long phases. It is back now and I have not noticed any pattern to when it comes and goes. It causes me extreme stress and anxiety, especially at night. Also causes bloat. I have eaten extremely healthy (organic Whole Foods) since I was born thanks to my parents, and I pay attention to deficiencies, eat 3 meals a day, have a smoothie in the morning, fast for 12-13 hours, etc. I also exercise 5 days a week (lifting, cardio, mobility work, etc) and avoid crunching movements due to the hernia. I take zinc, B12, D3, and am a pescatarian/gluten, dairy, corn free, no processed foods, no antibiotics, don’t eat late at night, don’t overeat, eat tons of veggies and fruit. Please let me know what you know and suggest regarding hiatal hernias. Thank you so much! Christie: Good morning. Sorry for the long post but I’m hoping you can help. My mom started with diverticulosis in 2007 and in 2012 it became “moderate” diverticulitis. It got continually worse and then in 2017 she had a bowel resection done. They removed a foot of her colon. Ever since then she has dealt with horrible gas and constipation. She just had endoscopy done a few weeks ago because she felt like things weren’t passing through and the doctor said her stomach was red and inflamed but she does not have h. pylori. She also has Gastroparesis. The doctor then put her on Zantac two times a day for 4 weeks and Miralax at night. She also takes the Beachbody digestive boost. Her doctor has also mentioned putting her on Linzess. She can’t afford testing because my parents are retired and on a limited income so I’m wondering if you think doing a certain protocol would help her without testing first. Can you recommend anything? I would appreciate any suggestions. I’m not happy with how things are going for her and really want to see her healthy again. Laura: Hi I have a couple of questions. I have only been listening for around a month so I may have just missed this. I haven’t heard dr Cabral talk much about beans and legumes, is the a reason why hey aren’t recommended or not at the top of the list! I’m primarily veggie and eat a lot of veg, however I do like to add lentils, beans or chickpeas to my food to add in protein and other nutrients! I was just interested to find out what your take is on this. Also, I’m going to start a naturopath nutritional therapy course in the UK next month so maybe I will find all this out for myself. However I have taken nutritional supplements before and I use to really be bought into juicing detoxing. However I have read various things that suggests that a supplements can actually shorten your life and aren’t as good as they seem. Also taking butrioanl shakes with condensed nutrients can actually be difficult for your body to digest all at once. For example you would eat a whole meal in a few minutes, therefore how is it ok for your body to process nutritional supplement shakes in such a short amount of time! Thanks Laura Katherine: Hi there, I'm from Windsor, Ontario, Canada and I'm wondering if there is a ND over here that you would recommend? I have benefits through my work that would cover my appointments so that's why I was wondering if Dr. Cabral would recommend someone over here? Thank you so much for your time, Katherine Meg: Hi Stephen, Being located in Australia, I don’t have easy access to wild salmon as all Australian salmon is farmed. Therefore I wanted your advice in regards to the best salmon choices. Would you recommend consuming wild tinned salmon over fresh farmed salmon? Is tinned salmon equally as nutritious? Renae: Hello Dr Cabral, My Mum was diagnosed with hemolytic anaemia a couple of years ago and has been taking pharmaceutical medication daily to manage this. We both believe that there must be a way of finding the root cause and getting to the bottom of it so that she can feel well and be medication free again. Other symptoms she experiences separate from the anaemia are under active thyroid, osteo arthritis, IBS, foggy brain and really bad memory loss. She is only 62. She has tried to improve on things like diet to help herself and has seen a naturopath briefly but has not seen a change in her blood levels or other symptoms. I gratefully discovered your work a few months ago and I am very hopeful that with your advice on what labs she should run and where to start that she can finally find her path to wellness again. In the meantime I have given her a copy of your book. I did write in to your team who recommended the HTMA and OAT (thank you team :)), however given this is not a common auto immune condition I just wanted to be sure if there were any other recommendations you would make. Huge gratitude for your work. Warmest regards, Renae. Julie: Do you have any protocols to address nighttime bed wetting in children? I have read that there may be imbalances or constipation that could cause this, but my pediatrician says it’s normal for boys and he will likely outgrow the issue (6 yr old boy) I have 3 children, 2 no longer had night time issues once potty trained and did not have to be “taught” to make it through the night. Thank you for your insight. I have learned so much from your podcasts already! Julie Brittany: What are gse Citracidal drops? (Referenced from cold sore notes on podcast, mix them with apple cider vinegar and cyanne pepper) Thank you for tuning into this weekend’s Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Specific Show Notes & Resources: http://StephenCabral.com/1003 - - - Dr. Cabral's New Book, The Rain Barrel Effect https://amzn.to/2H0W7Ge - - - Join the Community & Get Your Questions Answered: http://CabralSupportGroup.com - - - Dr. Cabral’s Most Popular Supplements: > “The Dr. Cabral Daily Protocol” (This is what Dr. Cabral does every day!) - - - > Dr. Cabral Detox (The fastest way to get well, lose weight, and feel great!) - - - > Daily Nutritional Support Shake (#1 “All-in-One recommendation in my practice) - - - > Daily Fruit & Vegetables Blend (22 organic fruit & vegetables “greens powder”) - - - > CBD Oil (Full-spectrum, 3rd part-tested & organically grown) - - - > Candida/Bacterial Overgrowth, Leaky Gut, Parasite & Speciality Supplement Packages - - - > See All Supplements: https://equilibriumnutrition.com/collections/supplements - - - Dr. Cabral’s Most Popular At-Home Lab Tests: > Hair Tissue Mineral Analysis (Test for mineral imbalances & heavy metal toxicity) - - - > Organic Acids Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Thyroid + Adrenal + Hormone Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Adrenal + Hormone Test (Run your adrenal & hormone levels) - - - > Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Omega-3 Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - > Stool Test (Use this test to uncover any bacterial, h. 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Podcast summary of articles from the August 2017 edition of Journal of Emergency Medicine from the American Academy of Emergency Medicine. Topics include difficult airway assessment, all terrain vehicle accidents, air artifact in ultrasound, hemolytic anemia, cerebral edema in diabetic ketoacidosis, and board review on adult asthma. Guest speakers include Dr. Jennifer Robertson from the Emory University and Dr. Balaji Nithianandam of the Metrohealth EM Residency Program
Jonathan from the podcast Arthro-Pod joins the TWiPerati to solve the case of the Peruvian Woman With Inguinal Insect Bite, and discuss warm autoimmune hemolytic anemic that develops after babesiosis. Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin Guest: Jonathan Larson Become a patron of TWiP. Links for this episode: Jonathan Larson (Twitter, Google Plus) Arthro-Pod podcast Warm hemolytic anemia after babesiosis (NEJM) Tickborne diseases of the US (CDC) Image credit Letters read on TWiP 131 This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free with your first purchase - WITH FREE SHIPPING - by going to blueapron.com/twip. Case Study for TWiP 131 Thailand. 39 yo man reports 7 months of coughing up bright red blood, several times with mucus. Otherwise feels well. Big fan of salted crab som tum. Fisherman, lives with family. Healthy, no past med/surg problems. No meds. On seeing him: afebrile, chest xray abnormal: area of increased opacification. Not a smoker. No toxic habits. Send your case diagnosis, questions and comments to twip@microbe.tv Music by Ronald Jenkees
How do you classify hemolytic anemias? What are common signs and findings in these cases? Can you explain hereditary spherocytosis, G6PD deficiency or pyruvate kinase deficiency? Join us on the Common Rounds as we talk through intra and extravascular hemolysis!
In this podcast we bring you an interview with Dr. Darren Wood of the Ontario Veterinary College at the University of Guelph. Dr. Wood is an Associate Professor of Pathobiology and a Diplomate of the American College of Veterinary Pathologists. In this podcast Dr. Wood discusses his CHF-funded research which focuses on immune-mediated hemolytic anemia (IMHA). This podcast was made possible thanks to the generous support of the Kenneth A. Scott Charitable Trust, a KeyBank Trust.
Click here for audio of lecture.
Vincent, Michael, and Cliff review the outbreak of bloody diarrhea and hemolytic uremic syndrome in Germany caused by Shiga toxin-producing Escherichia coli O104:H4.
Hemolytic Anemia 1 (01.27.10)
Hemolytic Anemia 2 (01.28.10)
Background: Intravascular lymphoma (IVL) is an uncommon disease characterized by atypical lymphoid cells growing inside the lumina of small vessels. The diversity of clinical presentation due to possible involvement of multiple organs often complicates its diagnosis. Case Report: Here, we report on a case of IVL with rapidly progressive dementia and Coombs-negative hemolytic anemia. Interestingly, the erythrocytes exhibited a decreased osmotic resistance. Bone marrow histopathology revealed increased erythropoiesis and, finally, a small monoclonal B lymphocyte population. Cerebral magnetic resonance imaging (MRI) demonstrated few micro-bleedings. Computed tomography (CT) showed bilateral ground-glass opacity of the lungs. Within a few days, the patient developed respiratory failure and died. On post-mortem examination, intravascular large B-cell lymphoma with almost complete infiltration of the brain and lungs was diagnosed. Conclusion: IVL should be considered early in situations of unexplained neuropsychiatric disease along with markedly elevated levels of lactic dehydrogenase, anemia, and hemolysis.
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